LOCUS       DBEJZV010000001       105656 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.01, whole genome shotgun sequence.
ACCESSION   DBEJZV010000001 DBEJZV010000000
VERSION     DBEJZV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 105656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105656
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.01"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            441..1802
                     /gene="trpE"
                     /locus_tag="ACL3S0_000001"
     CDS             441..1802
                     /gene="trpE"
                     /locus_tag="ACL3S0_000001"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGR1311008.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFYILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            1799..2365
                     /locus_tag="ACL3S0_000002"
     CDS             1799..2365
                     /locus_tag="ACL3S0_000002"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGR1311009.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            2376..3380
                     /gene="trpD"
                     /locus_tag="ACL3S0_000003"
     CDS             2376..3380
                     /gene="trpD"
                     /locus_tag="ACL3S0_000003"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGR1311010.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            3377..4144
                     /gene="trpC"
                     /locus_tag="ACL3S0_000004"
     CDS             3377..4144
                     /gene="trpC"
                     /locus_tag="ACL3S0_000004"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGR1311011.1"
                     /translation="MSQEFLARILEQKVREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            4131..4730
                     /locus_tag="ACL3S0_000005"
     CDS             4131..4730
                     /locus_tag="ACL3S0_000005"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGR1311012.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEVAE
                     LAKLIPADVKKVGVFVSPSRAELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            4708..5931
                     /gene="trpB"
                     /locus_tag="ACL3S0_000006"
     CDS             4708..5931
                     /gene="trpB"
                     /locus_tag="ACL3S0_000006"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGR1311013.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGSPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            5924..6700
                     /gene="trpA"
                     /locus_tag="ACL3S0_000007"
     CDS             5924..6700
                     /gene="trpA"
                     /locus_tag="ACL3S0_000007"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGR1311014.1"
                     /translation="MPKTLTEKLNAIKVTGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(6672..6773)
                     /locus_tag="ACL3S0_000008"
                     /pseudo
     CDS             complement(6672..6773)
                     /locus_tag="ACL3S0_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            7002..7733
                     /locus_tag="ACL3S0_000009"
     CDS             7002..7733
                     /locus_tag="ACL3S0_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311015.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDENSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            7748..8899
                     /locus_tag="ACL3S0_000010"
     CDS             7748..8899
                     /locus_tag="ACL3S0_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1311016.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(8951..9610)
                     /locus_tag="ACL3S0_000011"
     CDS             complement(8951..9610)
                     /locus_tag="ACL3S0_000011"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGR1311017.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEKSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            9680..10126
                     /locus_tag="ACL3S0_000012"
     CDS             9680..10126
                     /locus_tag="ACL3S0_000012"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311018.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            complement(10354..11532)
                     /locus_tag="ACL3S0_000013"
     CDS             complement(10354..11532)
                     /locus_tag="ACL3S0_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR1311019.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            11812..13080
                     /locus_tag="ACL3S0_000014"
     CDS             11812..13080
                     /locus_tag="ACL3S0_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR1311020.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLEDCE"
     gene            13077..13973
                     /locus_tag="ACL3S0_000015"
     CDS             13077..13973
                     /locus_tag="ACL3S0_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGR1311021.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            13988..14305
                     /locus_tag="ACL3S0_000016"
     CDS             13988..14305
                     /locus_tag="ACL3S0_000016"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1311022.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            14322..14639
                     /locus_tag="ACL3S0_000017"
     CDS             14322..14639
                     /locus_tag="ACL3S0_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR1311023.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            14649..16004
                     /locus_tag="ACL3S0_000018"
     CDS             14649..16004
                     /locus_tag="ACL3S0_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR1311024.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            16327..17802
                     /locus_tag="ACL3S0_000019"
     CDS             16327..17802
                     /locus_tag="ACL3S0_000019"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGR1311025.1"
                     /translation="MVQTKQPNIILIVVDQMRADVLSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NSPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            17799..18647
                     /locus_tag="ACL3S0_000020"
     CDS             17799..18647
                     /locus_tag="ACL3S0_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGR1311026.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGTPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            18662..19432
                     /locus_tag="ACL3S0_000021"
     CDS             18662..19432
                     /locus_tag="ACL3S0_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGR1311027.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(19710..19955)
                     /locus_tag="ACL3S0_000022"
     CDS             complement(19710..19955)
                     /locus_tag="ACL3S0_000022"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR1311028.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            20339..20578
                     /locus_tag="ACL3S0_000023"
     CDS             20339..20578
                     /locus_tag="ACL3S0_000023"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR1311029.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            complement(20689..20892)
                     /locus_tag="ACL3S0_000024"
     CDS             complement(20689..20892)
                     /locus_tag="ACL3S0_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR1311030.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(20923..21531)
                     /locus_tag="ACL3S0_000025"
     CDS             complement(20923..21531)
                     /locus_tag="ACL3S0_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR1311031.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(21570..21740)
                     /locus_tag="ACL3S0_000026"
     CDS             complement(21570..21740)
                     /locus_tag="ACL3S0_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGR1311032.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(21752..22318)
                     /gene="amaP"
                     /locus_tag="ACL3S0_000027"
     CDS             complement(21752..22318)
                     /gene="amaP"
                     /locus_tag="ACL3S0_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGR1311033.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(22402..22566)
                     /locus_tag="ACL3S0_000028"
     CDS             complement(22402..22566)
                     /locus_tag="ACL3S0_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR1311034.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            22969..24450
                     /gene="mgaSpn"
                     /locus_tag="ACL3S0_000029"
                     /gene_synonym="mgrA"
     CDS             22969..24450
                     /gene="mgaSpn"
                     /locus_tag="ACL3S0_000029"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGR1311035.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            24812..25813
                     /locus_tag="ACL3S0_000030"
     CDS             24812..25813
                     /locus_tag="ACL3S0_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1311036.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            25963..26880
                     /locus_tag="ACL3S0_000031"
     CDS             25963..26880
                     /locus_tag="ACL3S0_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311037.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            26891..27781
                     /locus_tag="ACL3S0_000032"
     CDS             26891..27781
                     /locus_tag="ACL3S0_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1311038.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            27810..29426
                     /locus_tag="ACL3S0_000033"
     CDS             27810..29426
                     /locus_tag="ACL3S0_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1311039.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGIGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            29436..30755
                     /locus_tag="ACL3S0_000034"
     CDS             29436..30755
                     /locus_tag="ACL3S0_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR1311040.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVVTGTDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHMDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(30963..31035)
                     /locus_tag="ACL3S0_000035"
     tRNA            complement(30963..31035)
                     /locus_tag="ACL3S0_000035"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31000..31002),aa:Lys,seq:ctt)
     gene            complement(31300..32571)
                     /locus_tag="ACL3S0_000036"
     CDS             complement(31300..32571)
                     /locus_tag="ACL3S0_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGR1311041.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            32841..33080
                     /locus_tag="ACL3S0_000037"
     CDS             32841..33080
                     /locus_tag="ACL3S0_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311042.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVYSNNGLKKYEK"
     gene            33245..33424
                     /locus_tag="ACL3S0_000038"
     CDS             33245..33424
                     /locus_tag="ACL3S0_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311043.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            33561..33740
                     /locus_tag="ACL3S0_000039"
     CDS             33561..33740
                     /locus_tag="ACL3S0_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGR1311044.1"
                     /translation="MPMTQKEMVKLFTAHGWIKTRGGKGSHIKIEKQGERPITILHGK
                     LNKYTERGIGKQAGL"
     gene            33777..34229
                     /locus_tag="ACL3S0_000040"
     CDS             33777..34229
                     /locus_tag="ACL3S0_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGR1311045.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFGYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            34520..34990
                     /locus_tag="ACL3S0_000041"
     CDS             34520..34990
                     /locus_tag="ACL3S0_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGR1311046.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            35009..36097
                     /locus_tag="ACL3S0_000042"
     CDS             35009..36097
                     /locus_tag="ACL3S0_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HGR1311047.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLVPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            36078..36506
                     /locus_tag="ACL3S0_000043"
     CDS             36078..36506
                     /locus_tag="ACL3S0_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR1311048.1"
                     /translation="MELEISDFLGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKIYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            36644..37594
                     /gene="prmA"
                     /locus_tag="ACL3S0_000044"
     CDS             36644..37594
                     /gene="prmA"
                     /locus_tag="ACL3S0_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGR1311049.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            37596..38339
                     /locus_tag="ACL3S0_000045"
     CDS             37596..38339
                     /locus_tag="ACL3S0_000045"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGR1311050.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            38350..40146
                     /gene="pepF"
                     /locus_tag="ACL3S0_000046"
     CDS             38350..40146
                     /gene="pepF"
                     /locus_tag="ACL3S0_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR1311051.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQINLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(40206..40883)
                     /locus_tag="ACL3S0_000047"
     CDS             complement(40206..40883)
                     /locus_tag="ACL3S0_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGR1311052.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            41130..41900
                     /locus_tag="ACL3S0_000048"
     CDS             41130..41900
                     /locus_tag="ACL3S0_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311053.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGDGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFWGLTGTEKEDLHV"
     gene            41893..42657
                     /locus_tag="ACL3S0_000049"
     CDS             41893..42657
                     /locus_tag="ACL3S0_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311054.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            43081..43872
                     /locus_tag="ACL3S0_000050"
                     /pseudo
     CDS             43081..43872
                     /locus_tag="ACL3S0_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
     gene            43983..44651
                     /locus_tag="ACL3S0_000051"
     CDS             43983..44651
                     /locus_tag="ACL3S0_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR1311055.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEK"
     gene            complement(44676..44945)
                     /locus_tag="ACL3S0_000052"
     CDS             complement(44676..44945)
                     /locus_tag="ACL3S0_000052"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311056.1"
                     /translation="MLKAVFEVIDKTDEVSSKHCFEVADRTDEVSLKHCFEVVDRTDE
                     VSLKHCFEVADRTDVVSNHTYGKVKLTWFEEIFEEYHTKKPCSSR"
     gene            complement(44995..45528)
                     /gene="queF"
                     /locus_tag="ACL3S0_000053"
     CDS             complement(44995..45528)
                     /gene="queF"
                     /locus_tag="ACL3S0_000053"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGR1311057.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEDLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(45833..46147)
                     /gene="trxA"
                     /locus_tag="ACL3S0_000054"
     CDS             complement(45833..46147)
                     /gene="trxA"
                     /locus_tag="ACL3S0_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR1311058.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(46164..46385)
                     /locus_tag="ACL3S0_000055"
     CDS             complement(46164..46385)
                     /locus_tag="ACL3S0_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR1311059.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(46485..46865)
                     /locus_tag="ACL3S0_000056"
     CDS             complement(46485..46865)
                     /locus_tag="ACL3S0_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR1311060.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(47008..47961)
                     /locus_tag="ACL3S0_000057"
     CDS             complement(47008..47961)
                     /locus_tag="ACL3S0_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR1311061.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(48029..49236)
                     /gene="sstT"
                     /locus_tag="ACL3S0_000058"
                     /pseudo
     CDS             complement(48029..49236)
                     /gene="sstT"
                     /locus_tag="ACL3S0_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            49375..49935
                     /locus_tag="ACL3S0_000059"
     CDS             49375..49935
                     /locus_tag="ACL3S0_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGR1311062.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            49992..50900
                     /locus_tag="ACL3S0_000060"
     CDS             49992..50900
                     /locus_tag="ACL3S0_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR1311063.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            50915..51442
                     /locus_tag="ACL3S0_000061"
     CDS             50915..51442
                     /locus_tag="ACL3S0_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGR1311064.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            51445..52551
                     /gene="yqeH"
                     /locus_tag="ACL3S0_000062"
     CDS             51445..52551
                     /gene="yqeH"
                     /locus_tag="ACL3S0_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGR1311065.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSNALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            52765..53076
                     /gene="yhbY"
                     /locus_tag="ACL3S0_000063"
     CDS             52765..53076
                     /gene="yhbY"
                     /locus_tag="ACL3S0_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGR1311066.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            53128..53757
                     /locus_tag="ACL3S0_000064"
     CDS             53128..53757
                     /locus_tag="ACL3S0_000064"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGR1311067.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            53757..54350
                     /gene="yqeK"
                     /locus_tag="ACL3S0_000065"
     CDS             53757..54350
                     /gene="yqeK"
                     /locus_tag="ACL3S0_000065"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGR1311068.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRSFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            54351..54851
                     /locus_tag="ACL3S0_000066"
     CDS             54351..54851
                     /locus_tag="ACL3S0_000066"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR1311069.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            54864..55217
                     /gene="rsfS"
                     /locus_tag="ACL3S0_000067"
     CDS             54864..55217
                     /gene="rsfS"
                     /locus_tag="ACL3S0_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGR1311070.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            55537..56277
                     /locus_tag="ACL3S0_000068"
     CDS             55537..56277
                     /locus_tag="ACL3S0_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR1311071.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDETPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            56318..58129
                     /locus_tag="ACL3S0_000069"
     CDS             56318..58129
                     /locus_tag="ACL3S0_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NACHT domain-containing NTPase"
                     /protein_id="HGR1311072.1"
                     /translation="MNIPIPFGDILEKEVITNIPKIYQKLKQIYNDLQFKTEEELGVV
                     YQEYLQFTYKKYSTVKTLLYKNEGKFLYDFYEHVYLDDNNSDLIETSNTELIFEKTSN
                     VILTGTGGIGKSMLVKHIFINQVQQATSIPIFIELKSLNESDFSENELVDFIYQEVQN
                     HHLNLEKKYFKATLEAGRYTIIFDGLDEVNPSKRSWLDKEIKEFVTLYNSNRYVLSSR
                     PSEEFIGWNQFAEYEIKKLNREQALSLIDKLNYDEKVKRRFYRELKDHLYDTHESFAS
                     IPLLLTIMLMTYEAGASIPNNLTDFYNQAFYTLYQRHDASKSGYKRELKAKLTPEEFR
                     NILAYIGLKTFFEGKVDFDRTTLDEIITKYCFKNNLELKTNDIVYDATHSACMMLQEG
                     VSLKFSHRSFQEYFAAVGVNQLDDKLQKQILIKWSEADRNNIVAHKTFMNALFKIQKE
                     RTYKNLCIPIIERMDEKYSRMGDITEKIVTCFNYFICRKDSRENKLELHFLLTKEVHF
                     YFSLQFLIFANLGIDILSISDYENIEKLESDIVSNWKINERKYYNMLNDDEKTLINKW
                     INGWYFSRHNYLKEWSIKFIEETTTQKRSLQNIIDSI"
     gene            58153..59250
                     /locus_tag="ACL3S0_000070"
     CDS             58153..59250
                     /locus_tag="ACL3S0_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR1311073.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILARLGIDSLAFGTEEVLD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVEAVATKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETS"
     gene            59488..59742
                     /locus_tag="ACL3S0_000071"
     CDS             59488..59742
                     /locus_tag="ACL3S0_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGR1311074.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            59746..60000
                     /locus_tag="ACL3S0_000072"
     CDS             59746..60000
                     /locus_tag="ACL3S0_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGR1311075.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            60191..61804
                     /locus_tag="ACL3S0_000073"
     CDS             60191..61804
                     /locus_tag="ACL3S0_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGR1311076.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            61934..62560
                     /gene="gmk"
                     /locus_tag="ACL3S0_000074"
     CDS             61934..62560
                     /gene="gmk"
                     /locus_tag="ACL3S0_000074"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGR1311077.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            62585..62899
                     /gene="rpoZ"
                     /locus_tag="ACL3S0_000075"
     CDS             62585..62899
                     /gene="rpoZ"
                     /locus_tag="ACL3S0_000075"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGR1311078.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            62965..65361
                     /locus_tag="ACL3S0_000076"
     CDS             62965..65361
                     /locus_tag="ACL3S0_000076"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGR1311079.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            65374..66309
                     /gene="fmt"
                     /locus_tag="ACL3S0_000077"
     CDS             65374..66309
                     /gene="fmt"
                     /locus_tag="ACL3S0_000077"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGR1311080.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            66302..67615
                     /gene="rsmB"
                     /locus_tag="ACL3S0_000078"
     CDS             66302..67615
                     /gene="rsmB"
                     /locus_tag="ACL3S0_000078"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGR1311081.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            67630..68370
                     /locus_tag="ACL3S0_000079"
     CDS             67630..68370
                     /locus_tag="ACL3S0_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGR1311082.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            68367..70346
                     /gene="stkP"
                     /locus_tag="ACL3S0_000080"
     CDS             68367..70346
                     /gene="stkP"
                     /locus_tag="ACL3S0_000080"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGR1311083.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            70461..71219
                     /locus_tag="ACL3S0_000081"
     CDS             70461..71219
                     /locus_tag="ACL3S0_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR1311084.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSIMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            71221..71670
                     /locus_tag="ACL3S0_000082"
     CDS             71221..71670
                     /locus_tag="ACL3S0_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR1311085.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            71732..72337
                     /locus_tag="ACL3S0_000083"
                     /pseudo
     CDS             71732..72337
                     /locus_tag="ACL3S0_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            72405..72653
                     /locus_tag="ACL3S0_000084"
     CDS             72405..72653
                     /locus_tag="ACL3S0_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311086.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            72784..73956
                     /locus_tag="ACL3S0_000085"
     CDS             72784..73956
                     /locus_tag="ACL3S0_000085"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGR1311087.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            73956..75230
                     /locus_tag="ACL3S0_000086"
     CDS             73956..75230
                     /locus_tag="ACL3S0_000086"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGR1311088.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANILNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(75266..76231)
                     /locus_tag="ACL3S0_000087"
     CDS             complement(75266..76231)
                     /locus_tag="ACL3S0_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1311089.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKK
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(76212..77666)
                     /locus_tag="ACL3S0_000088"
     CDS             complement(76212..77666)
                     /locus_tag="ACL3S0_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR1311090.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGIYYELDYGRKTN"
     gene            78043..79926
                     /locus_tag="ACL3S0_000089"
     CDS             78043..79926
                     /locus_tag="ACL3S0_000089"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGR1311091.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPSVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGPG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            80075..80962
                     /gene="scrK"
                     /locus_tag="ACL3S0_000090"
     CDS             80075..80962
                     /gene="scrK"
                     /locus_tag="ACL3S0_000090"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGR1311092.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(81005..81622)
                     /locus_tag="ACL3S0_000091"
     CDS             complement(81005..81622)
                     /locus_tag="ACL3S0_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGR1311093.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIDCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(82037..82250)
                     /locus_tag="ACL3S0_000092"
                     /pseudo
     CDS             complement(82037..82250)
                     /locus_tag="ACL3S0_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(82618..82809)
                     /locus_tag="ACL3S0_000093"
     CDS             complement(82618..82809)
                     /locus_tag="ACL3S0_000093"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311094.1"
                     /translation="MKSKEQTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            82931..83824
                     /locus_tag="ACL3S0_000094"
     CDS             82931..83824
                     /locus_tag="ACL3S0_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311095.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            83821..85020
                     /locus_tag="ACL3S0_000095"
     CDS             83821..85020
                     /locus_tag="ACL3S0_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311096.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(85373..86140)
                     /locus_tag="ACL3S0_000096"
     CDS             complement(85373..86140)
                     /locus_tag="ACL3S0_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311097.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(86157..86852)
                     /locus_tag="ACL3S0_000097"
     CDS             complement(86157..86852)
                     /locus_tag="ACL3S0_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311098.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(86857..87222)
                     /locus_tag="ACL3S0_000098"
     CDS             complement(86857..87222)
                     /locus_tag="ACL3S0_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR1311099.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            87362..87835
                     /gene="nrdR"
                     /locus_tag="ACL3S0_000099"
     CDS             87362..87835
                     /gene="nrdR"
                     /locus_tag="ACL3S0_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGR1311100.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            87836..89005
                     /locus_tag="ACL3S0_000100"
     CDS             87836..89005
                     /locus_tag="ACL3S0_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR1311101.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            89006..89902
                     /gene="dnaI"
                     /locus_tag="ACL3S0_000101"
     CDS             89006..89902
                     /gene="dnaI"
                     /locus_tag="ACL3S0_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGR1311102.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            89899..90628
                     /locus_tag="ACL3S0_000102"
                     /pseudo
     CDS             89899..90628
                     /locus_tag="ACL3S0_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
     gene            90642..91952
                     /gene="der"
                     /locus_tag="ACL3S0_000103"
     CDS             90642..91952
                     /gene="der"
                     /locus_tag="ACL3S0_000103"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGR1311103.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            92043..92378
                     /locus_tag="ACL3S0_000104"
     CDS             92043..92378
                     /locus_tag="ACL3S0_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311104.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWIYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            92518..92853
                     /locus_tag="ACL3S0_000105"
     CDS             92518..92853
                     /locus_tag="ACL3S0_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311105.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYIPLY
                     ALFSLSWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            93038..93829
                     /locus_tag="ACL3S0_000106"
     CDS             93038..93829
                     /locus_tag="ACL3S0_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311106.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIVTYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLEKYEDNV"
     gene            93822..94463
                     /locus_tag="ACL3S0_000107"
     CDS             93822..94463
                     /locus_tag="ACL3S0_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311107.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMILYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKV"
     gene            94467..95099
                     /locus_tag="ACL3S0_000108"
     CDS             94467..95099
                     /locus_tag="ACL3S0_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1311108.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKFDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            95127..95414
                     /locus_tag="ACL3S0_000109"
     CDS             95127..95414
                     /locus_tag="ACL3S0_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311109.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            95560..98073
                     /gene="secA"
                     /locus_tag="ACL3S0_000110"
     CDS             95560..98073
                     /gene="secA"
                     /locus_tag="ACL3S0_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGR1311110.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDIITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            98154..99185
                     /locus_tag="ACL3S0_000111"
     CDS             98154..99185
                     /locus_tag="ACL3S0_000111"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR1311111.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            99187..100218
                     /locus_tag="ACL3S0_000112"
     CDS             99187..100218
                     /locus_tag="ACL3S0_000112"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR1311112.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            100263..100625
                     /gene="acpS"
                     /locus_tag="ACL3S0_000113"
     CDS             100263..100625
                     /gene="acpS"
                     /locus_tag="ACL3S0_000113"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGR1311113.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            100615..101718
                     /gene="alr"
                     /locus_tag="ACL3S0_000114"
     CDS             100615..101718
                     /gene="alr"
                     /locus_tag="ACL3S0_000114"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGR1311114.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            101737..103752
                     /gene="recG"
                     /locus_tag="ACL3S0_000115"
     CDS             101737..103752
                     /gene="recG"
                     /locus_tag="ACL3S0_000115"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGR1311115.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLQTIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKSIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFACKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            103780..103983
                     /locus_tag="ACL3S0_000116"
     CDS             103780..103983
                     /locus_tag="ACL3S0_000116"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311116.1"
                     /translation="MKIKEQTRKLTAGCSKHCFEVVDETDEVSSKHCFEVADRTDEVS
                     SKHCFEVADRTDEVSNIYTVRRR"
     gene            104310..105290
                     /locus_tag="ACL3S0_000117"
     CDS             104310..105290
                     /locus_tag="ACL3S0_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGR1311117.1"
                     /translation="MKNSALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT        31874 a        19140 c        23348 g        31294 t
ORIGIN      
        1 acctacgata aggcgacgtt gacgcggttt gaagagattt tcgaagagta taaaggtgta
       61 ccgagatgaa catctcttca tcaatgtctc tggtcgtgga ggcaaggacc tagctgcgat
      121 tgcagattac tagaagctaa aaaataatag atggaaaaat tacagttctt tctctcacag
      181 agagcttgtg gttgctgaaa acaagcagag aaagctgtaa agttgggttc atctgaaacg
      241 agagaagaaa acatcattct caagggagtg ccctttatcg cacagcctgt tacaggagat
      301 atctgagaca ggaatgagag ataggagaaa tcctataatt gaggtggcac cgcgaatttc
      361 gtcctcacgc aagttatttt gcgtggggat ttttcataca gtcaccacgg actagaagta
      421 gaactgaaag ggaaattaca atggaacgaa tcattcatgg agatgtctta tcaccaatct
      481 tggcttatat gcgcttaaag gggcaacata aggttatttt agagagtatt ccgagagaca
      541 aggaaacagc tcgtttttat atcctagcct ataatccagt ttttgagatt aagtttgaaa
      601 atggggttct ctatcaaaat ggtcaagtga ttgatcggga tcccttggat ttcctttatg
      661 aagtgattca taagagtcag caccactcag agctaccttt tggtggtgga gccattggtt
      721 ttgtgggtta cgatatgatt tcgctttatg aagaaattgg tcaaatccct gaggatacaa
      781 ttgggacgcc agacatgcat ttctttgtct atgagagcta tatggtcttt gaccacaaga
      841 aggagaagat acatgtcata gaggatgcac tttatagtga gcgcagtcaa gaggccttgg
      901 aaaaatcctt gaaccaagtg cttgaggaat tacgcattcc tgctccaaat gaatttgaag
      961 atttggatct atctccgtta gacttcaaac cgcatatcgc tccacataag tttgagggaa
     1021 tggtagaaac agctcgtgac ttgattcgta acggagatat gttccaatgt gtactcagcc
     1081 agcgtttttc agcagaagtt actggaaatc catttgactt ctacagaaat ctccgcgtga
     1141 ctaatccttc taattacctt tatttctatg attttgggga ttatcaaatc atcggagcta
     1201 gtccagaaag tttagtttct gtcaaaaatg gcatcgtgac aaccaatccg attgcaggga
     1261 cgcgaccaag aggggctacg gatgaagaag acaagacctt ggcgactgac ctcctctctg
     1321 atgagaagga aacagcagaa catcgaatgt tggtagactt ggggcgtaac gatattggcc
     1381 gcatctctga aacggccagt gtccaagtta ctaagtatat gaaggtggag ctcttccgct
     1441 acgtcatgca tttgaccagc gtggtcaagg ggcgtttgct tccagaactc acggccatgg
     1501 atgccttgaa agctacactt cctgctggaa ccgtttctgg agcaccaaag attcgggcga
     1561 tgagacgcat ctatgaactg gaaacggaaa aacggggcgt atatgcagga gcaatcggct
     1621 acttgtctgc gacgggtgat atggatttgg ccattgccat ccgaaccatg attctcaaaa
     1681 atcaaagagc ctatgtgcag gctggggcag ggattgtcta cgactctatc gcccaaaacg
     1741 aataccaaga aaccattaac aaagcaaaat ctatgactag aattggagaa ctaagaccat
     1801 gattttattg attgacaact atgattcttt tacctataac ttggcccaat acattgggaa
     1861 ttttgcagaa gttcaggttc tgagaaatga tgattccaag ctgtatgaag aagctgaaaa
     1921 agcagatggt ctggtttttt ctcctggtcc tggttggcca gttgatgctg gaaagatgga
     1981 agacatgatt cgtgattttg caggcaagaa gccgattctt gggatttgtt tgggccacca
     2041 agccattgca gaagtctttg gtggtaagct aggtttggct ccaaaagtca tgcatgggaa
     2101 acagagcaat atcaactttg aagcgccatc tgttttgtat caaggtattg aggaaggacg
     2161 tgcggtcatg cgttatcaca gtattttgat tgaggaaatg ccagaagact ttgaagtgac
     2221 agctcgttcg actgatgacc aagccatcat ggggattcaa cataaaaacc taccgattta
     2281 tggcttccag taccatccag agagcattgg aacgccagac ggcttgtctt ctattcggaa
     2341 ttttatcgag aaggttgtaa agtgaggaaa ctaggatgaa agagattatt gaaaaactag
     2401 caaaatttga aaatttatca ggtgtggaaa tgacggatgt cattgagcgt atcgtaactg
     2461 ggcgtgtaac tgaagcgcag attgcttctc tcctcttagc tcttaagatg aagggggaaa
     2521 cacctgaaga acgcacagcc attgcccaag tcatgagagg acatgcccag catattccaa
     2581 ctgagattca tgatgccatg gacaactgtg gtacaggtgg ggacaagtct ttcagtttta
     2641 atatttccac aactgcagcc tttgtcttgg ctggtggcgg tattcacatg gccaagcatg
     2701 gtaaccgctc gatttcttct aaatctggtt ccgcagatgt cctcgaagcc ttgggaatca
     2761 atcttgacct caaaccagct gaactaggta aggtctttga taaaactgga atcgtctttc
     2821 tcttcgctaa aaatatgcac ccagctatga aatacatcat gccagctcgt ttggaattgg
     2881 gaattccaac gattatgaac ttgactggtc cactgattca tccaatggct ttagaaacac
     2941 agcttcttgg aattagtcgt ccagaactcc tagaaagtac agctcaggtt ttgaaaaata
     3001 tgggtcgcaa acgtgccatc gtggttgctg gaccagaagg gttggatgaa gctggcttga
     3061 acggaacaac caagattgca cttcttgaaa atggcgaaat cagcttgtca agctttactc
     3121 cagaggattt gggaatggaa ggctatgcta tggaagatat tcgtggtggg aatgctcagg
     3181 aaaatgcaga aattttgctt agcgttctga aaaacgaagc aagtccattc ttggaaacga
     3241 cagtcttgaa tgctggtctt ggtttctatg ctaatggtaa gattgatagc atcaaggaag
     3301 gagttgcctt ggcccgtcaa gtgattgcta gaggcaaggc ccttgaaaaa ctcagactgt
     3361 tacaggagta ccaaaaatga gtcaggaatt tttagcacga atcttagagc agaaggtgcg
     3421 tgaggtggag cagatgaagc tggagcaaat ccagcctctg cgccagacct atcgcttggc
     3481 agagtttttg aagaatcatc aggaccgctt gcaggtaatc gctgaggtca agaaagctag
     3541 ccctagtttg ggagatatca atctcgatgt ggatattgtg caacaggccc agacttatga
     3601 agaaaacgga gcagtgatga tttcggtgtt gacagatgag gttttcttta aagggcattt
     3661 ggattatcta cgggaaattt ccagtcaggt agagattccg acgctcaaca aagactttat
     3721 catcgatgaa aagcaaatca tccgcgctcg caatgcaggt gcgacagtta tcttgctcat
     3781 tgtggcagcc ttgtccgaag aacgcctcaa ggaactgtat gactacgcga cagagcttgg
     3841 tctggaagtc ttagtggaga ctcacaatct agctgaacta gaggtagccc acagacttgg
     3901 tgctgagatt atcggggtca acaaccgcaa cttgactacc tttgaggtcg acttgcagac
     3961 cagtgtagat ttagcccctt actttgagga aggtcgctat tacatttctg aatctgccat
     4021 tttcacaggg caggatgcgg aacgactagc cccatacttt aacggaattt tggtagggac
     4081 agctcttatg caggcagaaa atgtggccca gagaatcaag gagttgcaga ttgacaaagg
     4141 ttaaaatttg tggactatcg accaaagaag cggtggaaac agccgtttca gcaggagccg
     4201 actatatcgg ttttgtcttt gcacctagta aaagacaggt aactttagaa gaagtagctg
     4261 agttggcaaa gcttattcct gcagatgtca aaaaggttgg tgtatttgtt tcaccaagtc
     4321 gggcagaact gctggaagcg attgacaaag ttggcttgga cttggttcaa gttcacggtc
     4381 aggtggcaga tgatttattt gagaatttgc cttgtgctag cattcaggct gtgcaggtag
     4441 atggagaggg tcatgtgccc aattctcagg cagactatct actctttgat gcccctgtgg
     4501 ctgggagtgg ccagcccttt gattggggtc aactggatac gactggacta gcacagccct
     4561 tctttatcgc aggtggcctt aatgaagata atgtagtaaa agcaattcaa cactttactc
     4621 cctatgcagt agatgtatca agcggagtgg agacagatgg acaaaaagat catgaaaaga
     4681 ttagaagatt tatagagagg gtaaagaatg gcatatcaag aaccaaataa agatggattt
     4741 tacggaaaat ttggcggacg ttttgtccca gaaacattga tgacagcagt tttggagttg
     4801 gagaaggcct accgtgaaag tcaggcagac ccaagtttcc aagaggaatt aaaccagctt
     4861 ttgcgccagt atgtgggacg tgaaactccc ctttactacg caaaaaactt gacccagcat
     4921 atcggcggag ccaagattta tctcaaacgg gaagacctta accatacagg agcccacaag
     4981 attaacaatg ccttaggaca agtttggctt gccaaacgca tgggtaaaaa gaaaattatc
     5041 gcagaaacgg gtgctggtca gcacggtgtg gcaactgcaa ctgctgcggc cctctttaac
     5101 atggaatgta ccatctacat gggtgaggaa gatgtcaaac gccaagccct caatgtcttc
     5161 cgtatggagc ttttgggagc taaggtcgag gccgtgacag atggttcgcg cgtgctcaag
     5221 gatgcggtca atgcagccct tcgttcatgg gtggctaata tcgacgatac ccactatatc
     5281 cttggttctg ccttggggcc tcatccattt ccagaaatcg ttcgtgactt ccaaagtgtc
     5341 atcggtcgag aggctaaaca acagtaccgt gacttgacag gtcgagatct gccagatgcc
     5401 ctagtagcct gtgttggtgg tgggtcgaat gctatcgggc tcttccatcc ctttgtagaa
     5461 gatgagtcag tagctatgta tggaactgaa gcagcagggc ttggtgtgga tacagagcac
     5521 cacgctgcta ccttgaccaa gggtagtccg ggtgttcttc acggttctct catggatgtg
     5581 ctccaagatg cccatggtca aattcttgaa gccttctcta tctcagcagg tttggactat
     5641 cctggtatcg gtccagagca ttctcactac cacgatatca aacgtgccag ctatgtccct
     5701 gtgacagacg aagaagcttt ggaaggattt caactcttgt ctcgtgtgga agggattatc
     5761 ccagccttgg aatctagcca tgctatcgct tttgcggtga aattggccaa agaacttgga
     5821 ccagaaaagt ctatgattgt ctgcctatca ggtcgtgggg acaaggatgt ggttcaagtc
     5881 aaagaccgct tggaagcaga tgcagcaaag aagggagaag ctcatgccta agacactaac
     5941 agaaaaattg aatgctataa aagtaactgg aaaaggaatt ttcgttcctt atatcatggc
     6001 tggtgaccac gaaaaaggtt tggacggtct tgctgaaaca attcactttt tagaagattt
     6061 gggtgtctct gctattgaag tggggattcc cttttcagac cctgttgcag atggacctgt
     6121 tatcgaagaa gctggcttgc gcagtttagc ccacgggacc tctacccagg ctttagttga
     6181 aaccttgaaa accattgaaa cagagattcc actggtcatc atgacctact tcaaccccct
     6241 ctttcagtac ggtgtggaga actttgtcaa agatctggct gatacagctg tgaagggctt
     6301 gattatccca gacctgcctc atgaacatgc caactttgta gaaccatttt tggcagatac
     6361 agatatcgcc ttgattcctt tagtaagctt gaccacagga attgagcgcc agaaagagtt
     6421 gattgaaggg gcggagggat tcgtctatgc cgttgccatc aatggggtga cagggaaatc
     6481 aggcaattac cgtgcagatt tggacaagca cttggcgcaa cttcatcaag tggccgacat
     6541 cccagtcttg acaggttttg gtgtatctag tcaagccgat ctggaacgct tcaatgcggt
     6601 gtcagatggt gttatcgtcg gttcaaaaat agtaaaagct ctccaccaag gagagccgat
     6661 tcaggatttt atcagacaag cagtagctta ccaaaaataa tcaaacaagt agcaagtaag
     6721 aggaaaggca cgaaaggaag tctttccttt ttcttttgca ggagaaaggt cagttttata
     6781 gtgaattgaa tctggaatat tacactacgg ttcctaaaat attttcagaa agcgatttga
     6841 atttcccaat aaatttgttc agtttttaat tgattttact atagaagata taattttcta
     6901 aattactctg acacagaact ttaagaaaaa gctaattatt gtagtaattt ctttaagaaa
     6961 atgatataat tcattaaaaa gtatttggag gaggaagaat tatgttgaat caggatctct
     7021 ttgattcgct tgaggcacaa aaaattgtag atactttgat gaaagggcaa aaagattatg
     7081 tagatgaacg tctagaaaaa agagagacaa tgatagtgtc gaatggttat gcatggacgc
     7141 gacctaatca tattgatact gcatttgcat cagcagattt gtttgagtat aaattacaat
     7201 tagcaggaca gacttgggga tatttagaat ttgaaacaaa tacagaaaaa tatgggaaag
     7261 tattgttaat tataaagggt aagaagcgac ttacgaacca atttcctttg gtacaaaaaa
     7321 ataagagtgg ctacttattt gaatatgctc agatgaatac actttatctt aatcaacatt
     7381 cttcctacaa aaatgatgaa aatagtcatt cctttccaat tcagatggag ttagtttctg
     7441 atgaaatgat tcaagaaatt gaacaagcta ctaaaaattc gaatatcgaa aaatttatga
     7501 ttttaactta tgaggcggac tcagaaaaca atattatatc tgtagatgtt gttatgcctg
     7561 atgcacgaac tggtcagtta cacttgattc aagatttgtc tgagtatatt caatcaagtt
     7621 cgtaccattt cgaagaagct aaatatcaag atattcctaa tttttcagaa ttatcggaaa
     7681 cagaagattt tgaaattatt ccaagaatag aaaaacaaga aggtcaaaag tagtaaggag
     7741 tatgtaaatg tttaatggtc gggtattgaa agaattacgg ctgttaaatg gtttaagtag
     7801 agcagaatta gctcagagaa ttaatttaac ggaacaagcc atttggcagt ttgagtccaa
     7861 cgaaacgaaa cctaaattat caaccaaaat gcatttggcc aaccaatttc atgttgattt
     7921 aacttatttt gaacaggaag aagagagcat tcgatttgat tcttctgtaa ttgcctttag
     7981 aaatgcagac ctagcaacac ggaaaacaat agatattcaa actatgtatt tacataaggt
     8041 agatagtttg attgattatt ttgaaagttt tgtaattata cctaatatta taattcatga
     8101 cctaagtaat gtagtgagtg aatcttatca taagggagaa tccattgagg aattggctct
     8161 ttatgccagg gaaaaattag gtatttcaaa agataatcat gatttgcttt ataaattaga
     8221 acgttcaggc atctatatcg tggaacgatt aattaatggc caagctgatg cttatagcgc
     8281 atggtcaaaa ttgggaagac cttatattgt gttgggaacg aataaatcat ctgtacgtcg
     8341 aaattttgac ttagctcatg agctaggaca tattctttta cataaatata aagatatgaa
     8401 tgaagatggc gatcgtttgg agcaagaagc aaattatttt gcatcatgtt ttttattgcc
     8461 aaaagaagag tttttagtca aatttgaaga gagggttggc aagcgtgtca gcaatcctga
     8521 tagttatatt ttattgaagt cggatttgaa tgtttcgata caggctttag agtatcgagc
     8581 ttttaagtta ggattattga ctccaaagca acattcttac ttttatcgtc aaattgcgca
     8641 aaaaggttac aaaatgattg aacctttgga tgatcaaatt tttgttaaaa aaccaagcaa
     8701 agtaaagagt attctggacg tcgttttgag taatcatcta gtcagtctag cgactataat
     8761 gtctaaacaa agtattcgtt tacagtttat aagcgaaata ttttcagtcg aaatgaaatt
     8821 ttttgatcag tatcaagaag atagaagaac agatcgattt gataacatca tccctttgta
     8881 caaaagaaat aatttataat ttaactgtga aataatttca tgaaggacat atggcagaaa
     8941 ttggatttta tcagacaagc agtagcttac caaaaataat caaacaagta gcaagtaaga
     9001 ggaaaggcac gaaaggaagt ctttcctttt tcttttgcag gataaaggcc aggatacccg
     9061 tcgcagaagc aaactgaatc aagatcagta actccgttac gctaaagacg agagcacaag
     9121 aagctaaaaa gaggaaatct cctgcgccca tgcggatatc gataaaatga gccaaaattc
     9181 caagagcaag gaaggagacc atgaccagat tccagccaga ggaagctatt aggattaggt
     9241 ggaaagtcat ccagaccagt aagggatatt cctgatggtg aaagtcgtag atacccaagg
     9301 tcaaaccagc ggtgattagg acgacttgcc ccaaggaaag caattcccaa gagtaaagca
     9361 gaaagaggag tcctaagact aattcaaaga gggcatacca gacaggatag cgaactttgc
     9421 agtagcgaca gcgaaagcga ttgaagacct gtgagagaat cggaatcaaa tctaagggac
     9481 gcaagcgagt ctgacaggaa tcgcagtgac tggctgaact gataatggat ttctctggaa
     9541 aacggtcaat gaccaaacca agaaaggaag cgagaatgct cccgacgaga aaaaaataaa
     9601 aatcaatcat acttatctat tcgtaaaaaa tgggagaaat agtataatgg agaaacatag
     9661 ataagatggt gaggaaaaga tgacaattcg ttttgaagaa aaggtgagta tagaaaacgc
     9721 tcaatttgta tgccagtggt ccaactccct aggcaaatcc tttcaagaac aatggatggg
     9781 accaaggatt ccttttctac tgacccttca agccttggaa ggagtctttt caatctttga
     9841 tgaacaagag tttgtgggac ttatccagaa aatcaggcta gaagacagca atcttcatat
     9901 cgggagattt tttatcaacc cccagaaaca ggagcaagac ttaggtagcc aggctttaag
     9961 gaaatttgtt agtttggcct ttgaaaatga agatatagat agtatttctc taaatgtctt
    10021 cgaggcaaat caaagagctc agaatcttta ccaaaaagaa ggatttgaaa tcgttcaaat
    10081 ggttgaagca cctgtacgaa aatatagtag attgaaacta gaatagtaca cctctacttc
    10141 taaaacattg ttagaaatcg atttgactgt cccgatcgat tcgtcctgtt attatttcat
    10201 tttattatac attatgaaaa aggggagata ggagtataat tccaaatata aagaaagcga
    10261 acaaaacaga attctgattt tcagaaaaca ggtttattcg ctttttatga tatactccct
    10321 ctttttagcc tatttattaa atgtaataga aaattaagaa tgtagaattg tatgatacaa
    10381 acaaagtgca atagctgagt gtgcggctgt aaaatcattg taaggttcaa taatgacttc
    10441 aggtaggcga ttatagagca gtttgggttt gtagttcatt tcactatata gtttttggat
    10501 gatgtgttga tttgttagta aaggactatg taggtagatt ttttgagagt caatcatcat
    10561 actgatattt aaaatggttt gactaagata gagtaaggct tgatggataa gtgtgattat
    10621 tccagtgtca cctaattgat aagcggttaa aataacttgg atatcaatat catcggcatt
    10681 tttgactaaa ctaggaagta gagaataggg agattgatga tatagaattt ttgatttttt
    10741 gattaaccaa gattctccag caaaagtttg taagcatccc ttgcgcccgc agctacattc
    10801 ttctccctca gatgaaacaa ctgtatgccc tatttctcca atcattagat ttcctttccc
    10861 ataaatgttt ccgtcgtaga tataagaaca gtgcatacct ctagcaaaat gaaaataagc
    10921 aaaattaggg tcattctgtt ggcgactaaa taggcgttta cctatagcca tacagttaac
    10981 attgttagag aaaaacaaag gcttatcaaa gtgggattga atcatttcta agtcgatatg
    11041 ttgccataaa ggattgtttg ttgttatttt ataattatct aaatagcgac caggtagcgc
    11101 gattccaatt gcttctattt cataatcaga gcagttattt aagaattgct ttagtgtctg
    11161 gttaatgagt tgatttccct tttcttggat taactgttta gtaacaattt ctttctcttc
    11221 ctttaagata tttcctagat tatctcctaa agcaaaagtg aaatgttttt cagatagttc
    11281 acaaccaatg tagtaaaatc gtttagcttg aatgtctagc aggatttttt ttctccctac
    11341 gcttgtatcg tgttcgtctt caccaagttc taagagaata ttttctttaa tcagatcatt
    11401 tgtgatactg ctagttgttg caggtgttat tcctgtttta gtagcgattt caattcgtga
    11461 aatgggacct aatgtgtaaa ctgtttccag tattttagct cttagttgta attgtttctt
    11521 agataaggtc atattagttt tcttcctagt tgtcagattc ttaaaatcct atgatttttt
    11581 gctatggata aatgtagatg ttaatctttt taagcttttc attacttact ggtctctttt
    11641 tattatatat tgataataaa aaataatcaa atgtttacac aaatccttga caaggctttc
    11701 ttatagttgt aaaatataaa taacaaaaga taatcaaata acaacttgac gtcaaaaaat
    11761 aaagataatt gataactttt gataataaaa tatatttaag aggaaaaggt tatggaaaaa
    11821 ttattacaag aaaagttact tccagtagcg gctagattgg gtaataataa agcgttggtt
    11881 tctattcgag acggtattac tctaactata cctttattgt tgataggttc attactaatg
    11941 gttattgcaa gttttcctat tccaggatgg gaaaaatatc tgggtgatat tggtgttgct
    12001 gactatttat ggaagggtgt tgatagtagt tttggattac ttggtcttgt agctagtttt
    12061 ggtatcgctt actttatggc tagacaatac aaagttgatg gtattcctgc tggtattgtg
    12121 tcattatcat cttttattac agttacgcct ttcattagag gagaggctgg agcaggaatg
    12181 cctaccgctt tcatggcatc aaaaggttta tttgttgcta tgattttagg attgattaat
    12241 ggctatatct accaatggtt tataaatcat aatatacaga taaaaatgcc ggatggtgtt
    12301 ccaccagcag tatctaaaag ctttagtgcc attattcctg gtgcagtgac tattgttggt
    12361 tggttgattg tttatgcaac tttagataaa ttaagtttac ctaatcttca tgaaattgct
    12421 caagtagctt tgggaggtcc acttggactt ttaggaaata atgttattgg ccttcttatc
    12481 ttaattttcc ttaatagtag tttttggttt gtaggattac acggaggaaa tgttgttaat
    12541 gcagttatga aaccgttatg gttagctaat ctagatgcaa ataaagtagc ttatcaaact
    12601 ggagaaactc ttccaaatat ttttactagc gtatttatgg ataattttgt attcataggt
    12661 ggcggtggtg caaccatagg tttagttctt gcgttaggat atttagcaca taagaagaaa
    12721 gctagtaaac aactaaaaac tttggcacct ataactgtta tacctggatt atttaatata
    12781 aatgaaccag caatgtttgg cgttcctatt gttttgaaca ttttgttact agttccattt
    12841 atcttagctc caatgtttaa cttactagta gcgtggggag caatggcatc aggtttggtt
    12901 ccgctaactt atacagatcc aggttggact atgccacctg ttataagtgg tttacttgct
    12961 acaggaagta tttctggttc attattacaa attgtattga ttgttttgga tgtcttactt
    13021 tatttaccat ttgtaatagc tattgaaaaa cggtttaagt tattggagga ttgcgaatga
    13081 aacgtttaat tagtgcaaat ccatctgaga tattacagat gaatgctgaa gaattaaaac
    13141 aaagtatttt agcaagtgaa ggtagagttg ttctatctga aaatgtagtt actcgtgaga
    13201 catttgttgg ggatataact aattctgaaa ttgctagagc ttttggagct gatatgattt
    13261 tattgaattg tgttgatgtt tttgagccta aaatttatgc tttggatagt tcaggtgatg
    13321 atgttattca tcgcttacac cagcttgttg cttgtccaat tggtgtaaat ttggaaccga
    13381 ttgacccatc tgcaaagatg ctagaggaaa cacaggaaat tgttgcaggt cgtgttgcta
    13441 gtgttgaaac attgaagcga atagaggagt taggttttga ctttgtctgt ttgactggaa
    13501 atcctggaac aggagttagc aatcgagaaa tcattaaggc tgttcaaact gctaaggaaa
    13561 acttttctgg tttgattatt gcaggtaaga tgcacggggc aggagtgaat gagcctgtgg
    13621 cagagctttc tgtcgcagag caattgttgg aagcaggtgc ggatgtgata cttgttccag
    13681 cagttggaac cgttccagcc tttcatgacc aagagttgcg tgaagtcgtt gatctcgttc
    13741 atagtaaggg tggtcttgta ttgagtgcta ttggtactag ccaagaaaca tctgatacag
    13801 atactattaa ggaaattgca cttagaaata aaatttgtgg agttgatatt caacatatag
    13861 gtgacgcagg atatggggga ctggcaacag tcgataatat ttatgcattg agcaaggcaa
    13921 ttagaggagt gagacataca gtatctcgct tggctaggtc agtaaatagg tgataaagga
    13981 gtaagctatg gctaaagtaa caattatgtt agcatgtgca gcaggtatga gtacaagtct
    14041 gctagtgaca aagatgcaaa aggcagcaga agataagggg ttggatgcag aaatttttgc
    14101 agttccagct cctgaagcag aagaaattgt agcaacaaaa gaagtaaatg tgttgctttt
    14161 aggccctcaa gttcgctatt tactagggga ctttcaagaa aaactaaaag atagacagat
    14221 tcctgtggcg gttattccga tgacagatta tggaatgatg aatggttcta aagtcttaga
    14281 tttagctgaa agtttattag actaagattg aggagaatgc tatgaatgaa agtaatttag
    14341 aatctgcaat ggggctaatt atgtatggtg gggaagccaa aagtaatgct atggaggcta
    14401 ttcaggcagc aaaaaaaggg gatttctcta aagccaatcg aagattagct gatgcgaatg
    14461 ctgccttatt acaggcgcat aaggctcaaa cagaaatgtt gacaaaagag gcacaggggg
    14521 aagaaacatc aattagcctc ttgatggtac acgcgcaaga tcatttaatg acgagtctga
    14581 cctttgttga cttggcgaaa gaagtggtag aagtatacga acgatttgaa aaaaattagg
    14641 aatttgctat gaatacaatg ttggataaaa tgcaagaaaa actttctcca attgcaatga
    14701 aagttgggaa tcagaagttt ttagttgctt tacgtgattc atttgtgggg actatgcctg
    14761 ttattatgac aggttccatt gctttgttat taaatgcttt tctagtggat ttaccacaac
    14821 aatttcacct agaaagtatt acgaaaacct ttcagtggct tgttgacatc aataatttgg
    14881 tattcaaggg aagtatacca attgtttcct tattgttcat ctattgcttg ggagtgaata
    14941 tcgctaagat ttataaggtt gatacagttt ctgctggttt ggtatcgctt gcttcgtttg
    15001 tcatttcgat tggaagtaca gttacaaaga gtttcccttt ggcaaatgta ggagatgtga
    15061 aattagatca aatcttacaa ggaattgata atctagcatt tgatggtaaa aatctgatgg
    15121 taactattgg gaatgtgatt ccaggaaacc atattaatgc cagaggctac tttacagcca
    15181 tgatgattgg atttttagcc tctattattt tctgtaaagt aatgaaaaag aactgggtaa
    15241 tcaagttacc agattcagtt ccccctgcga ttgctaagcc gttcacttct atcattccag
    15301 gatttatggc gatgtatata gtagccatct tgacttatgt tttccattta cttagcaatg
    15361 acttattgat tgattgggtt tacaaggtgt tacaaacgcc attactaggt ttgtctcaaa
    15421 gtttctttgc agttattctg atgatctttt tgaataagtt attctggttt tttggtctcc
    15481 atggaggaaa tgtattggct cccatcatgg aagggctgtt tggagttgct atgttagcga
    15541 atctggatgc tttccaaaaa ggtgaaccga ttccttatat atggacaagt gggtcttttg
    15601 gggcgtttgt ctggtttgga ggattaggat tagtacttgc tattttaatt ttttcaagaa
    15661 acagtcatta tcgaaaagtt gctaaacttg gtctagcacc agttctgttt aatattggtg
    15721 agccggtcaa ttatggttta ccagttgtct tgaatccttt gctatttata ccatttgtac
    15781 ttagcccggt tttcatggca acggtagctt actgggcaac aagctggggt cttgtttcac
    15841 ctgttacaca aaacgttact tgggtaatgc ctccaatttt atatggtttc ttctctacag
    15901 catttgattg gcgtgccatc atcttatcag ttgtttgttt gattattagt gtcttgactt
    15961 atttcccatt tgtgaaaatg gcagataaaa ctgaattgag ttaatggtct tacttgcgtt
    16021 ttttgtgata aaatagaaat agattacgtg taagatgagt taggtgtagg atttcttatc
    16081 tccaataaaa ttgttattag acaaaggttt ataatttatt gaagttggaa tagtacactg
    16141 taacttctaa aacagtacta gaaaatgatt tgaatttcct aatcgattta gtcatatttt
    16201 agttcatttt tctataaaac ataacaagaa tgttattgtt ttatatagag agattgatat
    16261 agaaaggggt gcagtaaagg tagatatctt cttgtgcctc ttttgccata ttagaaagga
    16321 gattttatgg ttcagacaaa acagccaaat attattttga ttgttgtaga tcaaatgaga
    16381 gcagacgtct tatccttgaa tagtaaggat aagctagtta gcactccaac attagatatg
    16441 atggctagtg taggttataa ttttgaaaat gcctattctc cagttccttc ttgtgttcct
    16501 gctagggcag ctttattgac tggcttagac caagataaaa gtggacgagt tggttatcaa
    16561 gatgaggtgc cttggaattt tactaatact cttccaaaag tctttaaaga tatgggttat
    16621 caaacagagt gtattggtaa gatgcatgtt tttccttcca gacagagact tgggtttgat
    16681 catgtcttac ttcacgatgg gtatctacat gttgatagaa agtatgataa ggcttatgga
    16741 agtcaatttg attatgctag tgactatcta gcctttttaa agggtaaagt tggttatgat
    16801 gttgatttga ttgatgacgg aatggattgt aattcttggg aagctagacc ttgggataaa
    16861 gatgagaagt tacatccaac aaactgggtt gtgagtgagt ccatttcatt tttacaaaga
    16921 agagatccaa cggttccttt ttttctcaaa atgtcttttg aaaaaccaca tgctccatta
    16981 aattccccaa aatactattt tgatatgtat atggaacgct tgcctcaatt tctcgatttg
    17041 catatcggga attgggaagt attagaaaag caaattccgt ctatttatgc tttaagaggg
    17101 aaattaaagg aagatgatca aagaagaatg gttgctgctt attttggatt gattactcat
    17161 atagaccatc aaattagtcg ctttttgact gccctaaaag aatttcgtca tgataaagat
    17221 acgattatct ggtttgtttc ggatcatgga gatcagcttg gtgaacatta tctgtttaga
    17281 aagggatatc cttatcaggg aagtatccac attccttcgt ttatttacga tccggctgga
    17341 ttgatagctg gtaatagggg aacaatcaag caattagtga aaattcaaga tatttttcct
    17401 tcactcgtgg atttggcagg aggaactact acagatgaac tagatggacg gagtgttaag
    17461 aatttattat ttggacagta cgaggggtgg cgaacagaat ttcatggtga acatgcttta
    17521 ggaaaagatt ctagtcaata tatcttgaca gaccagtgga aatttatctg gtttcctgtt
    17581 ttaaatcatt atcagttatt tgatatgaaa aaagatccgc atgaaatgaa tgatttgtat
    17641 ccaagtgaaa aataccaacc tattgttcgt cagatgaaga aaaaattagt agactttctt
    17701 agatatagag aagaaggttt tgttgtggat gaagagttag ttcctgttga actttctaaa
    17761 ataacgccaa ctctaacgaa aacgggggat agtcaatcat gaaaatgaaa aaaatcaagg
    17821 gtgggacatt tatgatggga acaaattctg aagagggctt tttagatgat tttgaaggtc
    17881 ctcaagtcgc tgttagtgta aaggattttt ccattgcgga tactccagtt acgaatcaag
    17941 aatttgctca atttgtgaaa gaaacaggct ataaaacact agctgagcga caagagtggt
    18001 cttttgtttt tatattgttc gttccagagg cagaaaggga gggatatcct catcctgctg
    18061 ggactccgtg gtggttacaa gttccgaacg cttgctggaa acatccctac ggtgagaata
    18121 gtaatctagt gggtttagaa gaccatccag tagttcatgt tgctttagaa gatgcattgg
    18181 ctttctgtaa ttggagcgga atgtctttac cgactgaagc acagtgggaa tatgctgcta
    18241 gaggaggaag acaatctgaa tatccttggg gagatactct tttagaaggt ggatattatc
    18301 atgccaatac ttggcaagga agatttcctt atgaaaatac tgccttagat ggatttatag
    18361 gaacggctcc tgtctatgaa tttttaccta atgattttgg tctatatcaa atgattggga
    18421 atgtttggga atggtgtcgc aatccgagat ataccttatt agctagtttt aatgaagatg
    18481 actatgagtt accaaaatat gggatacaag atgaggagta tgctatcaga ggaggttcct
    18541 ttttatgtca ttgttcttat tgtaatcgat accgagtagc tgctagaaat ggatgtattt
    18601 ctacttccac tagtagccat ctaggtttta gatgtttgaa agaataggat ggacttaaaa
    18661 agtggttgag attatttatt ttctaatcat tataatagct agtggattgg gttctatatc
    18721 aggcatgggt ggtggaatta taattaagcc acttatggat agttttggat accattcggt
    18781 cagtgatatt gctttttatt ctagtttctc tgtttttata atggcgatta tttcaacaat
    18841 caaaagattt tcacaaagta aagagataaa atggagattg atttttacgg tatccttttc
    18901 ttctgtttta ggaggatttc taggtcatct tatttttcaa gttttgttat ctcagttatc
    18961 agtacggcta gtatccattg ttcaaatgat tttactattt gtgatgctac ttgtatcatt
    19021 tgttttaaca gattttaaaa aaacttatca atttgataag ataggattct atatgatttg
    19081 tggtcttcta ttgggcttga tttctagttt tttagggatt ggtggtggtc cgctcaatgt
    19141 atctttattg atggtgtttt tttctatttc gataaaagaa gcaacgatgt attctcttgc
    19201 aattattttc ttttcccagt tgtctcattt ggctacaatt gttgtggtta caggtttaaa
    19261 tcagtatcat ttagcacctg ttccagttat ttttcttgct tctatatgcg gaggggtatt
    19321 ggggacggtt gtatcaaaag tcttacctga aaattgggta agatactgtt ttaaagggat
    19381 gttattcttt gtcatgggaa tgactttata taatttattt catattttgt aaggtcagtg
    19441 tgaaaatatt taaatagact tcctgtaaaa actggattta acgccctcca tttgtcaaat
    19501 taagctagac agtcttacca actcagaaaa tacctgatga ggtatttggt atccaaagga
    19561 tttaggtggg atgtgatttc ttgaggctgg gaaaaagtct ttaaaattaa aaaatgtata
    19621 atatcaggtg ttggaaaaac tttgatacta tgcgttttat tgtgggaata tttatttcat
    19681 tttctcctga aattgagttt ttacccagcc taaaattctt gactgacttc gttgaaatct
    19741 gtctgctttg gcaagtcatg acaccttaaa agtctatttg aatgttcgtt gagacaccgc
    19801 tgtcttggac atcctagatt cgcaaaaaag ctctcactat cgtgatgatt ggaaatatct
    19861 ttccattttg aaaactcttt tccacagtca aacgtaatag atttaaagag gttcactaga
    19921 aattgtgcca gccacccttg gatggattct gccatatcct ttgccttacg actcttggtc
    19981 ttcaaactga caatcaattg actatacctg ttcgctcaca aataggagag aactttttac
    20041 gaaaatctaa tgaatatgcc acaagaacat tataccgcaa cgtgtactat ttttggttca
    20101 ttttactata gaaactattg aagcacctgt acgaaaatat agtagattga aactagaata
    20161 gtacacctct acttctaaaa cattgttaga aatcgatttg actgtcccga tcgattcgtc
    20221 ctgttattat ttcattttac tatacattat gaaaaagggg agatagaaag caaacagcct
    20281 tgaaatcaat gttgactgcg attatgaacc tgaatcagcc cctcaaaagg gactgtatat
    20341 gaatgaacgt taccagtgtt taaaaactaa agaatatcag gcacttttat cttccaaggg
    20401 tagacaaatt ttcgctaaac gtaagattga tatgaaatct gtctttgggc agataaaggt
    20461 ttgtttgggt tataagagat gtcatctgag aggtaagcgt caagtgagaa ttgacatggg
    20521 attcatactc atggccaaca acctgctgaa atataataag agaaagaggc aaaattaaaa
    20581 agctagagtt ccgcaattgg gaatctctag ctttttgttt tctgagaatc atcttgactc
    20641 agactctttt gactaatgtt accaaaaaag ataaagtaac ttttaacctt atttatcgtc
    20701 gccactcaac atgtttttaa caccttctac agcaccttct acagcgtctt tagcgtcttc
    20761 ggcaacttct tttactttag aaacaacttt ttcagctgct ccttcttttt ccattttttc
    20821 atcaccgatg gctttcccaa caccttcttt aatagaacct ttagcttgat ttaatttttc
    20881 ttctactgac atgataattt ctcctgttat atttatttta tcttagttta cacgagtgtt
    20941 ttcgtgagat actacaccat ttgctgcacc tttaacagct tctacacctt cgctaacttt
    21001 ttcttgaaca gttgagaaac cagatccaag accagattta gctttttcga attgttctga
    21061 agtgaattct cctgttgatt cagcaacgtc agatacgcga tcttgaaggc ttactgagtc
    21121 tgcttcatgc tgttctttag ttttgatgtc gacaacgttt acgttgattt caacaatttc
    21181 caagtcagtc attttagcaa cttctgaaga tacgatttct ctgatttctg aatataaagc
    21241 tggaacattt ttttggtact caacaataac gtttaagtca actgcaactt gtgttttacc
    21301 aacttctacg ttaacaccac ttgttacgtc atcgctgtta acgatttttt ctttaagatt
    21361 tgagaagaaa ccaccatcga ttcccaaaag acctgaaacg ttttctagtg aaagaccaat
    21421 gattttttgg ataactttat cttcgtaagt aagttcccct ttgatttcgt gagctacaac
    21481 agtagcatct ttcttttcta cgttagtgtt tgtgtttttt tcgtttgaca tatgaaactc
    21541 ctttaattaa attagtaatt tttatttttt tatttatcta tatagttttt ttcgatatat
    21601 aatccagctg caactcccag tgctcctaaa atcaatacaa atattgtttt gaagaagcca
    21661 aaggagacaa tcaaacaagc cagaaatacg cctatgagac cagcgataat tggatatcga
    21721 tattgtttaa gccattccat tttttacttc cttacttcac acgactaaca gtctttttgt
    21781 tttgaggttt tggttggtaa ttttttactg caacttcaag ttttacttga cgctcaatac
    21841 caaaaaactg cttcaatcca ttagttattt cattttgaat tatttggcat ctgtcagcga
    21901 tgttgtctga aggaagaatt ttaccttcta catgaacgaa acatttattt tttcgtaaat
    21961 ttacatgaac agttgggttc ttgatcaatc tatgatcact caccaaactt ctaacaaaac
    22021 cttcgattgc cgaattcttt aattttaatg tatcgttttt agtttcaagt tggatttcca
    22081 agtaacgttt aggataaaac atcacaacta aaatggataa taaaactaaa gttgatagaa
    22141 ccactgtccc ccaaaagaca tatctagcaa gatagaattc aactacggag ttctgtctcc
    22201 agctaagtag atgaatacct agatcactaa cttgatgata atctatcaaa acaggaagga
    22261 aaattgtcaa gattaaaata cagaaaataa tgaaacatat tttctttgct tttgacatat
    22321 acaatccttt cgatttaaca tttaaactat ttttcccgtc attgatttaa aaatagtttg
    22381 ctaactttac tggcgaaaag tttactttct acctgtaaag aatgacacta cagtaatcac
    22441 aatcgctgca cctacaatag atgggagcaa agccattcca gcgattgatg gaccccaact
    22501 acctaaaaga gattgtcctg catatgcccc gactaaacca gcgaatacat ttgcgatgat
    22561 tcccatagaa ctactttttt agtgatttta cctgccaaga gaccaataag acctccagca
    22621 ataattgatc acaacactgc ctaccctcct tttttatttt aatatcaaaa aatcaatttc
    22681 tttgattaat actattatat aactttaata tagaaaagtc aattatttcg attgttatta
    22741 ttatataatt tttaaaatta aaaatataat ctttagactt gaatttgatt ctgtattcac
    22801 gccctcaata gacggtaaaa taagaaaatt gtttatatat tgtctccgta gtgttattat
    22861 acgaaataaa agattttagg aaaagtcgtt atatcatgct atacctattc tttgtggtat
    22921 aattgcaaga ggtttaatcc gataatttat aaagagagaa agatattcat gagagattta
    22981 ttatctaaaa aaagtcatag gcaattagaa ttattagaat tattatttga acataaacgt
    23041 tggtttcatc gttctgaact agcagagtta ttaaattgta cagaacgtgc agtcaaagat
    23101 gatctatccc atgttaaatc tgcttttcct gacttgattt ttcattcttc tactaatggt
    23161 atacgcatta ttaataccga tgatagtgat attgaaatgg tttaccatca tttctttaaa
    23221 cattcaactc atttttcgat tttagaattc atcttcttta atgaaggttg tcaagctgag
    23281 agtatttgta aagaatttta tatcagttca tcttcgctct atcgtattat tagccaaatc
    23341 aataaagtga ttaaaaggca atttcaattt gaagtcagtc tgacccctgt tcaaatcatt
    23401 ggaaatgaga gagacattcg ttactttttt gcacaatatt tttcagaaaa atattatttc
    23461 ctagaatggc catttgaaaa tttttcatca gagccactat ctcaattgtt agaattggtt
    23521 tataaggaaa caagctttcc aatgaatttg tcaacgcata gaatgctaaa gttgctccta
    23581 gttacgaacc tatatagaat aaagtttggt cattttatgg aagtagataa agattctttt
    23641 aacgaccaaa gtttggattt tttaatgcag gcagaaggaa tagaaggtgt tgctcagagt
    23701 tttgaatcag aatacaatat ctctttagat gaagaagttg tttgccaatt atttgtgtct
    23761 tactttcaaa aaatgttttt catagatgaa agtctcttta tgaaatgcgt aaaaaaggat
    23821 agttatgttg aaaaatctta ccatctattg agtgatttta ttgatcagat ttcagtcaag
    23881 tatcagattg aaatggagaa taaggataat ctgatttggc atctgcataa taccgcacat
    23941 ctgtatcgtc aagagttgtt tactgagttt attttatttg atcaaaaagg gaatacaatc
    24001 aggaactttc aaaatatttt tccaaaattt gtttcagata taaaaaaaga gctttctcac
    24061 tatttagaga ctcttgaggt ttgttctagt tcaatgatgg taaatcatct atcttatacc
    24121 ttcatcactc ataccaaaca tttggtgatt aatttgctac aaaatcagcc taaactaaag
    24181 gttttagtta tgagtaattt tgatcagtat catgcaaaat tcgttgcaga gacactttct
    24241 tattactgta gcaataattt tgaactggaa gtttggactg aattagaatt atcaaaggaa
    24301 tctttagaag attcacctta tgatatcatt atttctaatt ttattattcc tcctattgaa
    24361 aataagagac tcatctattc aaataatata aacacggtct cactcatata cttgttaaat
    24421 gccatgatgt ttattcgatt agatgagtaa gcaaaaataa caaaaaaacg ctatttcgcg
    24481 tttgaactgt acctcaaaag ttagacagaa aaaatctaat ttttggggtg tttttgttaa
    24541 gaaaagacct tcaatcattt aagcaaaatg tacatctaga tttatagccc tctaaaactc
    24601 ttgctttttt tgtagaagat acgaaaaaag ccataaaacc aaggcttttc ctgttttatg
    24661 tagatgttta cacatgaaaa ttgaagtatt ttcaaaagct aattggagtg attttattca
    24721 tgatgggata aatgatctgg ccaaaaatga ttgagaaata gttgcttaaa aagcatttgc
    24781 atgatactat atattgaaag gaggtgataa tatggtagaa caaagaaaat caattaccat
    24841 gaaagatgtt gctttagaag caggagttag tgttggaact gtttcacgtg taattaataa
    24901 agaaaaaggc attaaagaag taactttgaa aaaagtggaa caagcgatta aaactttgaa
    24961 ttacattcca gattactacg ctagaggaat gaaaaaaaat cgaacagaaa cgattgcaat
    25021 cattgtacca agtatctggc atcccttctt ttcagaattt gctatgcatg tggaaaatga
    25081 agtctataag agaaataaca aattactctt atgttctatc aatggtacaa atagagagca
    25141 agactatctg gagatgttgc gtcataataa agttgatgga gtggttgcca ttacctatag
    25201 tccaattgaa cattacttga cgtcaggaat tccctttgtt agtattgacc gcacatactc
    25261 agatattgcc attccttgtg tttcatcaga taatgatgca ggtggaagag aagcagctaa
    25321 acaattaatt agtaaaggat gtcagcattt agcctttgtg ggcggacata atacaaccat
    25381 taatgaaacc aaacgtcgta gaatttcatt tgaaaagtat gtccaagagc ataaaatacc
    25441 tcttagtatt tttgatttgg atgagacagt tactgactat tatggaaagc tagagagttt
    25501 cttggaagaa aattcttcta tagatggaat ttttacaatc aacgatttta cagctttgga
    25561 tgtgattgaa atactaaaaa aaaatggcaa acgtattcct catgatgtcc aaattattgg
    25621 atacgatgga attaaaatgg ctggagatag agattatcta ctttcaacta ttgaacaacc
    25681 attggaagaa atggcaaaag aagcggttcg tattttgttt gatataattg atggaaagac
    25741 tgttaatttg cagacaatcc taccagtaaa atttgttgaa ggaaaaacaa caaaaaatga
    25801 aaataagtct tgacagaaag cgctatcaat gatagaatga attcagataa aaagatttat
    25861 ttttaaaaca aaaatgaaac gtttcaaaaa agaaataaaa agacagcgcc aagcgctatc
    25921 ttttctagaa aaaaatgaaa cgtttcaaaa aaggaggttg ctatgaatag caaagcgaag
    25981 caagtttctc tttgggaaag aatcaagaaa caaaaactct tgttattgat gactgtcccc
    26041 ggtttagttt taacctttat ctttaaatac atccctatgt atggggtttt aatcgcattt
    26101 aaagattaca atcctttaaa aggaatttta gggagtgatt ggattggttt ttctgagttt
    26161 acaaaattca tatcctctcc caactttggt atcttgttag ccaacacatt aaaattaagt
    26221 atctatggtt tattgcttgg ctttttacca ccaatcattc ttgcgattat gctcaatcaa
    26281 ctcttgagtg aaaaagtcaa aaaacgaatt cagctcattt tatacgcacc aaactttatc
    26341 tcagtcgttg ttattgtcgg tatgattttc ctcttctttt cagtgggagg accaatcaac
    26401 aattttcttt ctatgtttgg aatgaaggct gacttcttga caaatccaga cttctttaga
    26461 cccttataca tctttagtgg tatctggcaa ggaatgggct gggcttcaac gctctacacg
    26521 gcaacattgg taaatgtaga tccagcctta gtagaagcag ctcgactgga tggagccaat
    26581 atcttccaac gaatctggca cattgatatt ccagctctta agcctattat ggttatccaa
    26641 tttgttttag ctgcaggtgg aattatgaat gtcggatatg aaaaagcatt cttgatgcag
    26701 acatcgttaa atttgccaac ttctgaaatt atctcgacat atgtctataa agttggtctt
    26761 gtatcaggag actattctta ctcaacagcg gttggtttgt ttaatgcagt gattaacgta
    26821 gtattgcttg ttgcagttaa ccaaatcgtt aaacgcatga ataatggtga aggaatttaa
    26881 ggaggaaagt atgaaaaatt cgattatgga tacaaaattt gatagacgta tcttactctt
    26941 aaataaaatc attattgtct ttatcgtttt gatgactttg cttcctttac tttatatcgt
    27001 cgtagcatcc tttatggatc ctaaggttct ggttagtaga gggattagct ttaatccagc
    27061 cgattggact gtagaaggtt accagcgtgt attcagtgac caatctattc taagaggttt
    27121 tatcaattct ctactatact cttttggatt tgcagcttta acagtcttgc tatctgtgtt
    27181 tacagcttat cctctttcca aaaaagattt ggtagggcgc cgttggatta actacttctt
    27241 gattgtgact atgttctttg gtggtggttt agtcccaact tacttgctcg taaaagaatt
    27301 gggaatgctc aatactccat gggctatcat tgttccaggt gctgtcaacg tttggaatat
    27361 tattcttgct agggcctatt tccaaggatt gcctgaagaa ttagttgaag ctgctgtcat
    27421 tgatggtgca aatgatttac agattttctt caaaatcatg cttcctcttg caaaaccaat
    27481 tatgtttgtt ctcttccttt atgcttttgt aggacagtgg aactcatact ttgatgcaat
    27541 gatttatatc aaggatccaa acttggaacc attgcaactt gtacttcgta aaattctcat
    27601 tcagagccaa ccaggtcaag acatgattgg agcacaagcg gctatgaatg aaatgaaacg
    27661 tttagctgaa ttgattaaat acgcaactat tgtcatttcc agcttgccat tgattgttat
    27721 gtatccattc ttccaaaaat actttgataa aggaattatg gctggttcac ttaaaggata
    27781 aaaaaagaaa aaataaaagg agttttctca tgaaattcaa aacattctca aaatcagcag
    27841 ttttgttgac agctagttta gcagtacttg cagcctgtgg ctcaaaaaat acagcttcaa
    27901 gtccagatta taagttggaa ggtgtaacat tcccgcttca agaaaagaaa acattgaagt
    27961 ttatgacagc cagttcaccg ttatctccta aagacccaaa tgaaaagtta attttgcaac
    28021 gtttggagaa ggaaactggc gttcatattg actggaccaa ctaccaatcc gactttgcag
    28081 aaaaacgtaa cttggatatt tctagtggtg atttaccaga tgctatccac aacgacggag
    28141 cttcagatgt ggacttgatg aactgggcta aaaaaggtgt tattattcca gttgaagatt
    28201 tgattgataa atacatgcca aatcttaaga aaattttgga tgagaaacca gagtacaagg
    28261 ccttgatgac agcacctgat gggcacattt actcattccc atggattgaa gagcttggag
    28321 atggtaaaga gtctattcac agcgtcaacg atatggcttg gattaacaaa gattggctta
    28381 agaaacttgg tcttgaaatg ccaaaaacta ctgatgattt gattaaagtc ctagaagctt
    28441 tcaaaaacgg ggatccaaat ggaaatggag aggctgatga aattccattt tcatttatta
    28501 gtggtaacgg aaacgaagat tttaaattcc tatttgctgc atttggtata ggggataacg
    28561 atgatcattt agtagtagga aatgatggca aagttgactt cacagcagat aacgataact
    28621 ataaagaagg tgtcaaattt atccgtcaat tgcaagaaaa aggcttgatt gataaagaag
    28681 ctttcgaaca tgattggaat agttacattg ctaaaggtca tgatcagaaa tttggtgttt
    28741 actttacatg ggataagaat aatgttactg gaagtaacga aagttatgat gttttaccag
    28801 tacttgctgg accaagtggt caaaaacacg tagctcgtac aaacggtata ggatttgcac
    28861 gtgacaagat ggttattacc agtgtaaaca aaaacctaga attgacagct aaatggattg
    28921 atgcacaata cgctccactc caatctgtgc aaaataactg gggaacttac ggagatgaca
    28981 aacaacaaaa catctttgaa ttggatcaag cgtcaaatag tctaaaacac ttaccactaa
    29041 acggaactgc accagcagaa cttcgtcaaa agactgaagt aggaggacca ctagctatcc
    29101 tagattcata ctatggtaaa gtaacaacca tgcctgatga tgccaaatgg cgtttggatc
    29161 ttatcaaaga atattatgtt ccttacatga gcaatgacaa taactatcca agagtcttta
    29221 tgacacagga agatttggac aaaattgccc atatcgaagc agatatgaat gactatatct
    29281 accgtaaacg tgctgaatgg attgtaaatg gcaatattga tactgagtgg gatgattaca
    29341 agaaagaact tgaaaaatac ggactttctg attacctcgc tattaaacaa aaatactacg
    29401 accaatacca agcaaacaaa aactagaggt tgattatggg agataagaaa tacacagtag
    29461 aaaaagccaa tcgttttata gcagaaaata aacatctcgt taatactcaa tataagcctg
    29521 aagaacattt ttcagctgag attggttgga tcaatgatcc aaatggattt gtttattttc
    29581 gtggagaata ccatctcttt tatcaattct atccatatga tagtgtttgg ggacctatgc
    29641 actggggaca tgctaaaagt aaggacttgg tgacttggga gcacttgcca gtggcacttg
    29701 ctcctgacca agattatgac cgaaatggtt gtttctcagg ctctgccatt gtcaaggatg
    29761 atcgcctctg gctcatgtac actgggcata tcgaagaaaa aaccggtgtc cgccaagtgc
    29821 aaaatatggc attttcagat gacgggattc actttgaaaa gatttcccaa aatccagttg
    29881 taactggaac agacttgcca gatgagttga ttgctgctga tttccgtgat ccaaaactct
    29941 ttgaaaaaga tggacgctat tactccgtag tagctgccaa acacatggat aatgtgggct
    30001 gtatcgttct actagggtcc gataacctag tagaatggca gttcgaatcc atctttttaa
    30061 aagggggaga acaccaaggc tttatgtggg aatgcccaga ttacttcgag ttagatggga
    30121 aagattgcct tattatgtca cccatgcgtt atcagcgtga gggagactca tatcataaca
    30181 tcaactcatc gcttttgttc acgggtaagg tagattggag agaaaaacgt tttatcccag
    30241 aatcagttca agaaattgat catggccaag acttctatgc gcctcaaaca ttgttggacg
    30301 atcaaaatcg tcgtatcctg attgcttgga tgcagacatg ggggcgtacc cttccaaccc
    30361 atgaccaaga acacaaatgg gcatgtgcca tgactttacc tagaattcta agattggaag
    30421 atggcaaact aagacaattc cctgttaaaa aaggccaata tcaaatccaa atagataaag
    30481 attgtcatta ccacttagga aatgatacag attatcttga atttggttat gacagtaatg
    30541 cgcagcaagt ttacattgat cgtagccatc ttattcaaaa aattctaggt gaagaagaac
    30601 aggacactag tcgacggtat gtagatattg aagctaaaga attggaagtt gttctagata
    30661 aaaattccat cgagattttt gtcaatcaag gtgaagcaag cttgactgca acttattact
    30721 taacggtgcc agctgagcta tcacgaattg attaaaaatt aagttatttc tcctaaagaa
    30781 aaagttctct ttctaaaata gtggaaagag gactttttgt gttttgggta tataagctta
    30841 gtttatggta tttgtaaaat tggtgttgga ttatgattta aactagtttt ctaaagaatt
    30901 tgaaaaaaat tttatttaag caaaaaaacc ttggttccaa ggcttttcct gttgtattta
    30961 gatgccccct acagggatcg aacctgtgac ccacggatta agagtccgct gctctgccag
    31021 ctgagctaag gaggcaaaga aaaaagctgt attggtgccg aaacttcacg gtttgtattg
    31081 aacccgcgca attaagcagg tgggcaactc gctctaactg aagctgtttc cgtgtgagac
    31141 ggcctacatg ctgttagaag acttttgttt ccctaataat acaaaaaata gtcggtcaac
    31201 acttaagtgt gaagtcgtac accacagcgt ttctatactt atatgatacc actttttcaa
    31261 aaaaaatcaa gaggaaagtg caattttttg aaaaggattt cagatttttc gcaaacgatc
    31321 gatagcttcc tttctttgag ccaaagcccg ttcatattta ccagtatctt ctgcttggaa
    31381 atagtgatga ttacgaattt tttctggcag atagtcttgc ttgatccaat ttccaggata
    31441 gttgtgtgga tagagatagt cttgggcatt ccccagttcc ttgcttccac tgtagtgccc
    31501 atcacgcagg tgtcgcggaa taggcaagtg ccctgatgtt ttgaggtcag caagtgcctt
    31561 atccatagct acataggctg agttggattt tggagaaagg gccaaatcaa tcacgacatt
    31621 ggcaatgaga atgcgggctt cggggaaacc aatcctttgt gcagcatcca gagcagtcac
    31681 ggtatgaatc tgggcctcag gattggctaa gccaatatct tcataggcga taacagtcaa
    31741 gcgacgagcg agactaggca gatccccagc ctcaatcaag cgggcagcat agtggagact
    31801 ggcatccaca tctgagccac ggatagactt ttgcagggca gatagaacat catagtgacc
    31861 gtctccatcc ttgtccatag tgatgtagct tctctgaaga ctattttcca tgatgtctaa
    31921 ggtgatgtgg cgaatgccct cgtcattctc aggggtagag agaacagcca agtccagtga
    31981 gttaaaggca gagcgaaggt ctccgtttgt agaggttgcg atgaaatcca gcgcatcctc
    32041 atctagttct attggaaaat caaaaccacg ttcagggtta cttagagcta tctgcagggc
    32101 ctctttgacg tcttggttag acagaggttc caactcgaaa atttgaacac ggctacgaat
    32161 ggcaggagtg acagagaaga aaggattttc agtcgttgct ccaatcatga tgaccagtcc
    32221 actttccaag agaggcaaga ggaagtcttg cttggtctta tctagtcgat gaatttcgtc
    32281 tagcaatagg acgagaccac cagaaaattt agcttcttcc gagatttctt gcagtcgctt
    32341 tttactatca actgtcgcat tgaaagttcg aaaggcatac ttggtcgttc cagcgatggc
    32401 agaggcaata ctggttttgc cgattccagg agggccatat agaatcatgg aggacaggcg
    32461 gttggcttcc accatgcggc ggatgatttt tccaggtccg accagatgct cctgaccgat
    32521 gacctggtcg atggttttag ggcgcatgcg aagcgcgaga ttgtctggca tagcagtcct
    32581 ttctaacgtg gatttgagta gaatgactca tctactatat cttactatgt ccattctagc
    32641 ctattagttg tgatatttca atggttttgt aataatcagg gagtgagata gaatcttttt
    32701 tactatttaa tttaaagagg agaggtatca gcatgagaga tttgattttc cttaaagctc
    32761 aaaataggat agttgagcct aaagaagtgg aagtgctgac ttgagaaata atattgctaa
    32821 atgtcattgt atgaactata atgaaaagag aggtgataag caatggaaat gatggaccaa
    32881 gtcaggaaat tttgattttt acaaaacaaa ttcgtcattg gattcttagt gatcaagtta
    32941 tttcagggaa aagaaaactt ttcttccggg aagatactcc aaaagagatt ttagatttgt
    33001 acgaaaacat taaatctaaa cttgattttg cttaccaaga agtttattct aataatggat
    33061 tgaaaaaata tgaaaaatag aataattgat gtttttgaag tagtaaatcg cctccttgta
    33121 ataactgttg aaaatcctga tttcgaagac ttgagagtta atcatactca atgaaaatca
    33181 aagagcaaac taggaaacta gccgcaggct gtacttgagt acggtaaggc gacgttgacg
    33241 tggtttgaat ttgattttcg aagagtatca gtttgtaaaa attggagata aaaaatatag
    33301 agtacgcagt ggtcctatga ttcattcaac tccgcctcaa tctgtcttag atcgagatac
    33361 ttttacaatt gactatacag atgatgaatt gctcgataaa gaagcagttt ttactactca
    33421 ttagaaaaat aggtctgaat aaattggttt cccttagaac cacatctagg ggcttttatg
    33481 tataatagaa taataagtat cactccttta caatacgtgt aacacgtgtt ataatggtgt
    33541 tgtcaggagg taaaagcgct atgcctatga cacaaaaaga gatggttaaa ctctttacgg
    33601 cccatggttg gataaagact agaggcggta aaggctccca tattaaaatc gagaagcaag
    33661 gggaaagacc tatcacaatc cttcatggta agctgaataa gtacactgaa agagggatag
    33721 gaaagcaagc tgggttgtaa aattcagtcc ctgctttttg atatggaggt agtgaaatgt
    33781 tagttacgta tccagcttta ttttattatg acgacacaga cggaacagaa gcgacttatt
    33841 ttgtccattt cccagatttt ggatactcag ctacacaagg agaggggatt tctgaggctt
    33901 tggctatggg gtcggagtgg ctagggataa ctgttgcaga tttgatagag agtgatggag
    33961 agttacctca gccatcagat atcaatagct tgtctttaat tgataatgat ccttttaaag
    34021 atgatgaaga tttcgtgtca acctatgacc ttgataaatc ttttatttct atggtatctg
    34081 ttgatgtatc agaataccta ggaagtcagg aacccattaa aaagactttg accataccaa
    34141 aatgggcaga taagttggga cgagaaatgg gacttaactt ttctcagact ttgacagacg
    34201 ctattgcaga taagaaagtt caagcctaag attaagcgtg gtatcgtggt aatagtcaat
    34261 aaaaaagcac gtccacttgt gctagttact cgcctattga ttttatagat ttattagccc
    34321 tttcgagggc tttttatatt gatttttatg agaaatgaag aaatcagact tttaagaaaa
    34381 tcactgatac caagggttta aatgaggtaa tatggtataa ttaggacata aaataatttt
    34441 gtggtaagat ggtagtatct attttagcat atttccgagc aatcggggcg attaaagagt
    34501 cgcatagaaa gaggacaaaa tggcaacata cggattttta gatattttag aggaagagtt
    34561 ggacaagaac tttccctttg actttgagat tagctgggat aaacgcaacc atgcggtaga
    34621 agtgagtttt ctattggaag cgcaaaatgc tgcaggtgtg gagatggtgg atgaagacgg
    34681 agaggtttca tcagatgaca ttctttttga ggaagcggtc cttttctaca atcctgccaa
    34741 gtcaacagtc aatgaggaag actatttgac tgttattcct tacctgccta aaaaaggatt
    34801 ttcccgtgaa tttttagctt attttgcgct tttccttaaa gatactgctg aggttgggct
    34861 agatgtcctc atggactttt tggaagaccc agaagcagag gaatttgtca tggaatggaa
    34921 ccaagaagtc tttgaagaag gaaaagttgg cttggaagag ggagaatttt acccttatcc
    34981 aagatactag gagttggttg gaggtgttat gaagaaaatt gggacttatt tggtttatgt
    35041 gctagctgtt gtctttatta tgctagcttt tgcttgtgga acaatcgcat ttgcagagtt
    35101 ggggtattcc gcagttttag cctttacttt tggttatgcc ttcgctcttc taagcatgta
    35161 tttaatcttt attcttcatg agctgggtca tgctttttgt ggctacttga caggctatcg
    35221 gctggtggct tttggattag gacattttat tttgaccaaa aagtcaggca ggtttcatct
    35281 tagtagaaca gccattctga aaaatgttgg tgctcaatac attggtttaa aagaggatga
    35341 aagcgatcaa agaatcatcc tgatgctttc aggaggcttg atggttcatc tcggcttgat
    35401 attattggcg atagtgtttg gatttttgac aagaagctgg tattttgcag ggacttggat
    35461 ttttcttaat ttatctttct tcctaaataa cattttgcca gtcgacatca ccgatggagc
    35521 aaaaatttgg gaattactac aacaccctga aaataccaaa tacgcctacc tggtattgag
    35581 acattctgct caaactttgc tggttcctca agaatatgat ttgaaagact ttgttcaagc
    35641 agttcctgag gatgcacgag ggagttttgc ggatggtgta ttaggtatgc aaggtgaagt
    35701 ttccattttg gaagggaagg aagaagtagc taaacagcag tttcaagcat tacttgagag
    35761 gacaactact ccgatgatgc agacagttgc ccaactatcc ctgcttcata tcgccttgtt
    35821 ggaaggagat tttgagcaag cggagcaata tgctagtatt cgacaggtca aatcgtttct
    35881 gtctctcaaa ctgtccaatc ttcaagtgat acaagcctgg tatcaattaa aggtgaagaa
    35941 agatgtagat cgaactcgta aggctctcaa gattgctaga cagaaaatgg atagtagtcg
    36001 aatgttgagg gacgagaaac gctattatga aaacttgtta gcagagctgg aaaaggaaat
    36061 gttagaagga actgaagatg gaactagaaa tttctgattt cctaggctgt aagattgctt
    36121 tgttttgtgg ggataagctt ttgactatct tacgcgatga taaggcaagc attccctggg
    36181 ccaatatgtg ggaactgcca ggtggtggac gtgaaggtga tgaaagtcct tttgagtgtg
    36241 tagcgcgtga agtttatgaa gaactgggca ttcatctgac tgaagattgt ctgctttgga
    36301 gtaagattta cccaagtatg ctttttgcag acaaacagtc cgtttttcta gttggtcagt
    36361 tgacacagaa ccagtttgac agtatcgtat ttggagatga aggacagggc tatcagctga
    36421 tgaatgttga ggaatttctt agttccagtc aagttgtgcc tcagttgcaa gagagattaa
    36481 aagattattt aaaagtaagt gattagaaag gatggttcgg ttaaatttct aaactgaacc
    36541 cgccctaaac acggtgccaa aaagataaac ttctcttaga cacaaacgtc ttcagagaat
    36601 ttcctatttt ggttttgtgt tttacgggct tggtatctta ataatggaaa catggcaaga
    36661 gttaaaagtt acagtgaagc gtgagggaga ggagttggtt tccaatctct tgattgagct
    36721 aggagcgcaa ggagtcgcaa tcgaagacag tatggactat atgggaaatg tggatcgttt
    36781 tggcgagatt ttcccagagg tggagcagca agaagaaatc gtagtgacag cctactaccc
    36841 tgacacggtg gatgtgacag tggttgaggc ggacttgcag gctcgcttag cagaattgac
    36901 ggattttatg gatttgggag agttaaaaat aggtacgact gccttggctg aggaagactg
    36961 ggcagacaac tggaagaaat actatgagcc agctcgtatc actcatgatt tgaccatcgt
    37021 tccctcttgg acagactatg aggcgactgc gggggaaatg attatcaagc tggatcctgg
    37081 tatggctttt ggtactggaa cccacccaac taccaagatg agcctttttg ccttggaaca
    37141 ggttcttcgt ggtggcgaaa cggtgctaga tgtggggact ggttcagggg ttctctctat
    37201 tgccagctcg cttctggggg ctaaagaaat tttcgcctat gacctggatg atgtggcggt
    37261 tcgtgtggct caggaaaata ttgagctcaa ccctggcatg gaaaatatcc atgtagcggc
    37321 tggagatttg cttaagggtg tggaaattga ggcagatgtg attgtggcta atatcttggc
    37381 ggatatcctc attcatctaa tagacgatgc ttatcgcttg gtaaaggatg aaggctacct
    37441 gatcatgagt ggcattatca aggacaagtg ggacatggtg cgccagtcgg ctgagtcagc
    37501 tggatttttc ctcgaaactc acatggttca aggggaatgg aatacctgtg tctttaagaa
    37561 aaccaaggat atctctggtg tgattggagg ctagcatgca gcagtatttt gtaaaaggca
    37621 gtgctatctc tcctgtcact atcgaggaca aggaaaccag taagcatatg tttcaggtta
    37681 tgcgcttgaa agaagaggat gaggttacct tagtctttga tgatggcatc aagcgcttgg
    37741 cgcgcgtgct ggatatggaa aatcgtcagt ttgagttggt ccaagaatta aatgacaatg
    37801 tggaactacc agtccaagtg accatcgcat ctggatttcc caagggagac aagctggagt
    37861 tcatcgctca aaaagtaacc gaactggggg ctagccaaat ctgggccttt cctgcagact
    37921 ggtcagttgc caagtgggat ggcaagaaat tgggtaaaaa agttgaaaaa ctagaaaaaa
    37981 ttgcccttgg agcagccgag caaagcaagc gtaatattgt accaagtatt aaacttttcg
    38041 agaaaaaagc agattttcta actcagctgg accagtttga ctctatcata gtagcctatg
    38101 aagaatcagc taaagaagga gaagccgctg cgcttctgca agcagtcact ggtcttgaaa
    38161 caggagccaa actgctcttt atctttggtc cagaaggcgg tctctcacct gcagaaatcg
    38221 aaagttttga agctaaggga gccgttttgg taggcctagg tcctcgtatt ttgcgagcag
    38281 aaacagcacc gctttacgcc ttatcagccc ttagtgtttt agtagaatta gagaaataag
    38341 aggaagaaaa tggaacaaaa acaccgttca gaatttccag agaaggaact ttgggattta
    38401 acagctctat accaagaccg tgaggatttc ttgcgtgcaa tcgagaaagc tcgcgaagac
    38461 atcaaccagt ttagccgtga ttacaagggc aatcttcaca cttttgagga tttcgagaag
    38521 gcctttgcgg aattggaaca gatctacatt cagatgagcc atattggcaa ctatgctttt
    38581 atgcctcaga cgacggacta tagcaatgac gaatttgcaa atattgctca agctgggatg
    38641 gaatttgaaa cagatgccag cgtagccttg accttctttg acgatgcctt ggtggtagca
    38701 gacgaggaag tcttggaccg tttgggtgaa ttgcctcact tgacggcagc tattcgtcag
    38761 gccaaaatca aaaaagccca ctatctaggg gctgatgtgg agaaggcctt gactaatctc
    38821 ggtgaagttt tctatagtcc gcaggacatt tatactaaga tgcgagctgg ggattttgaa
    38881 atggctgact ttgaagccca tggcaagacc tataaaaaca gctttgtcac ctatgagaat
    38941 ttctaccaaa atcacgagga tgctgaggtt cgtgagaaat ccttccgttc cttctcagag
    39001 ggacttcgta agcaccaaaa tacggctgca gcagcctatc tggctcaggt caagtctgaa
    39061 aaactcttgg ctgatatgaa gggatacgac tctgtctttg attatcttct agctgaacaa
    39121 gaagtggacc gtgtcatgtt tgaccgccag attaacctca tcatgaagga ctttgcacca
    39181 gtcgctcaga gatacctcaa gcatgttgcc aaggtaaatg gtcttgaaaa gatgaccttt
    39241 gcagactgga aattggactt ggacagcgcc ctcaatcctg aagtgactat tgacgatgcc
    39301 tatgatttgg tcatgaagtc ggtagaacct ttggggcaag aatattgtca ggaagttgct
    39361 cgttaccaag aagagcgctg ggtggacttt gctgctaaca gtggcaagga ttccggtggt
    39421 tatgcggcgg acccatatcg cgtacaccct tatgtactca tgagctggac aggccgtttg
    39481 agcgatgtct ataccttgat tcatgaaatc gggcattctg gtcaattcat cttttcagac
    39541 aatcaccaaa gctatttcaa cgcccacatg tcgacctatt atgttgaagc accgtcgacc
    39601 ttcaatgaat tgctactcag tgattactta gagaaccagt ctaatgaccc acgtcaaaaa
    39661 cgcttcgctc tggctcatcg cttgacagac acctacttcc ataatttcat cacccacctc
    39721 ttggaagccg ccttccagcg taaggtgtat acattgattg aagaaggaga aaccttcgga
    39781 gcaagcaaac tcaacagcat tatgaaggaa gttttgacag atttttgggg cgatgccatt
    39841 gaaatcgacg acgatgcagc tttgacttgg atgcgccaag ctcactacta tatgggcttg
    39901 tatagttaca cttactctgc tggtcttgtc atctcgacag ctggttacct tcatcttaaa
    39961 aactcagaaa ctggagctga agactggctc aatctcctca aatcaggtgg tagcaagaca
    40021 ccacttgagt cagccatgat tatcggtgct gatatttcaa cagacaaacc actccgtgat
    40081 accatccaat tcttgtctga cacagttgac cagattatcg cctacagtgc tgagttgggg
    40141 gagtaagggg atagagaggt tgttatagaa tgggtatgga cagttatttg cttaaaagtc
    40201 catgtttaaa tcccccattc cttttcgagg aattctttgc ccttctctgt aatggtaagt
    40261 gaacgtggcg tttgtgcagg gatgaccaat tgtttttcac tgaaaaattc taaaagagca
    40321 ttgccgagag ctccgccgac atgattttta cgttcgctcc aatccaaaca tttagggcaa
    40381 aatttccgtt ttttcttttt caattcatcc gtatcaatgt gtaattttct ttggaaataa
    40441 gacttcccag cttcagtgag ttggaagtct ttttctgatt cgctgaggag attttcttgc
    40501 aagagataat tggtaatgga aatgccaagc tcaccagcaa tatggtcata gcaggtgcga
    40561 gcgaccttta attccttttt gtgaatgtgt tgtttataac ttttgacatc acgctgagga
    40621 gagtagaagc tgagaaattc cagcatttct gcaatggcag cactttttaa agaataataa
    40681 tgaaaacgtc cataggtttg tagagtggtt acctgcgctt cggtaagtaa tttgaggtga
    40741 tagctgacag tatgttgctt gattttggta aagctggcaa tttcgttaac cgtgtgagct
    40801 tttccatcca ttagaatatc taaaatgtgc atccgagaag ggtctgataa gagttttgtg
    40861 atgatgaaaa tatctggttc cataaaaatt ttctccaaat ttcatatatc gatgattttc
    40921 tatcttttat tatactataa ttaaagcaca agaaaaatag attttaaaaa tgttttacta
    40981 gagaatattt taaattttat tgtctgagtt taaatggagg taaaattaca aaagtaattg
    41041 cagcagtatc cacagttgaa ggacgttaat cttaagatta cattctcaac attttttcaa
    41101 aagtgagatg aattaacaaa gtatccaaca tgctctattt gtgggggaaa gaaagagtga
    41161 agaagttaag tgttaaaaat ctaaaaaagc aatatggttc ttatgaagct gtcaagggaa
    41221 ttagctttga attgggagac ggagagtgtt tgggtatctt gggaatcaac ggtgctggca
    41281 aaacatccac tttaaagatg atttactcac tgacctcaat ttcctcagga gagattgata
    41341 tcttggggca aaatattgaa accaatcgtc gtaagagtaa atcttgtctg ggtattgtag
    41401 ggcaggagga tatgctggac atgaccttga atgtttatga taatcttttt gctcacggtc
    41461 tatgttatgg tatctcatct gtcgaactta ggaagagaat cgattctctc ttggattttg
    41521 ttcaactgag caaacatgcg caaaagatgg tgaatcagct gtcgggtggg atgcgacgac
    41581 gtcttgtctt ggcaagagct ctcatcaatc ggcctgatat tatcatttta gatgaaccga
    41641 cagttggttt agacattcaa tcccgcaata ttatttggga taaacttttg gaattgaagg
    41701 aattaggtgt ttctatcatt attacttccc actatatgaa tgagattgaa tatttgacag
    41761 atagggtgct gatgctccac caagggacta tcaaagaaga aggaactgta gaagacttgc
    41821 tcatcaagta tgatgctgac aaccttgaga cgcttttttg ggggttgact gggacagaga
    41881 aggaggactt gcatgtttaa gttatcattt cactccatcg gacacgttgt ggtacgcaac
    41941 tacatgagtt ttagaaattt atttaaaatt tcaattgtcc ccaaccttat cgaccccctc
    42001 ttttatcttt tagcaatggg atttggagtt ggtgcttatt tgacgcatgt taacggtatg
    42061 ctctaccgtg attttgtcat tacaggttta attgctgcga ctgccatgtc tgcggccacc
    42121 gcagaaacaa cggtcaatgc ctttatccag tataagattg aaaagactta tgatgctatg
    42181 ttgatgacgc caatcaatac gaatgatatt gtggtaggtc aggctatctg ggcaggtatt
    42241 cgtgcagtga ttttcggtgg gattttttgg ctgatttcca tgcttatcac agcgcatttt
    42301 catgtcttga tgttattgat tcctctgatt ttatttatag tgggttattt gtttggtgtt
    42361 ttgggactaa tctttaccta cttggcgccg tctagggaat ttctgaatta ctacaatgtt
    42421 ttggtaatcc gtcctcttta tatgttttca gataccttct ttcccattac ttccttgccc
    42481 ccaatacttg gtgatttgac ttggttttct cccttgtatc acgctacccg catgattcgt
    42541 attatatggg gaggtgaggt gacaggtttg tatcttcatc ttatctggtt gatagccttg
    42601 gcgctcttga taacggtgct tcctatgtat atgttacatc gtagatatta tagatagtct
    42661 aattatttgt gatgttgtag tcatattcta atttatacta aacgttattc gaatttggac
    42721 aggtatggga actgtgccta tcaatattgt aatttatgga agttgaaata gtacggttca
    42781 gtttttaaat attgttagaa attgttttaa attccctaat caatttgtat agtttttatt
    42841 tcactttatt ataactagtt tttcgcaatt tttgagacag gaatgtgatt tttgtgataa
    42901 ggttctatca ttacaagttt atttgttgta atatggaata aatcatttat atatcttttc
    42961 agaaatatgc tgtttctctg aatataaatg tctttttctt tttaacttaa ttttacaaat
    43021 tggtaaggtc atttaagact gcctttttga acagttgcta gaaatgtaga ggtattgacc
    43081 atgtatcaag atttactaag aaaaatagca gaagaaaaac caaattataa ccaggaggaa
    43141 atccagtggt tgcttgatca tttgggagat ccttctccag aaattcgtga tgaccttgtt
    43201 tttacaagct ttgctagagg gattcaggaa gagctattta cacaggaaca atttcatttc
    43261 attgctgaag gggtttcatc tgatggaggg ttagataaag agattgataa gataggcctg
    43321 ccaacacttg aacgttcttt tagggcgctt atttatgcaa ctctcttgtc tgacgatgcc
    43381 aaccagcaat cggtttttta tcaggaatta aatgcaggat ttcgtaatga cctttcaaat
    43441 caaggcttgc actatctttc aaaagaaaag gatacaacag gtttctcaag tcagtatggt
    43501 tgggttcacg cttttgcaca tggagccgat ttactgacag aggtggtttg tcatccagac
    43561 tttcctaaaa acagagttca tgaagtattt gatatacttg gccaactatt taaaaggatg
    43621 tcgattcgct ttacagatga tgaggattgg cgtttagcaa gagtgatcta tgaacctatt
    43681 ttataaggga agttggagca agaacaagta gcttcttgga taaaaactgt tgattttccg
    43741 atagaagaaa gggaggattt ttacaaattt tccaacttta gatcctgtct ggtggaagtc
    43801 tatgtccaac ttgaccagag aaatagttta caagatgagt tgaaagaagc tatccagtct
    43861 tttcaatact agagattagc taatagttct atgattttca aaaaatttcc aatcaatttt
    43921 cttgaaaccc tttcctactt ttgatagact agtatctagt ttttgaaaaa aggagaaaga
    43981 aaatgaaaaa atttgttgct gagttaatcg gtacgttcat gcttgtgttc gttgggacag
    44041 gagctgttgt ttttggaaat ggtcttgatg gccttggtca ccttggaatc gcctttgcct
    44101 ttggtttggc aatcgtggtg gcagcctact caatcggaac tgtttcaggt gctcacttga
    44161 acccggctgt ttcgattgct atgtttgtaa acaaacgttt gtcatcttca gaacttgtaa
    44221 actacatcct tggtcaggtt gttggagctt tcatcgcttc tggcgcagtc ttcttcctct
    44281 tggctaattc aggtatgtca actgctagtc ttggtgaaaa tgccttggca aacggtgtca
    44341 ctgtctttgg tggtttcttg tttgaagtca ttgcaacttt cttgtttgtc ttagttatta
    44401 tgactgtgac ttcagaaagt aagggcaatg gcgcgattgc tggtttggta atcggtttgt
    44461 cattgatggc gatgattctt gtcggattga agattactgg actttcagta aacccagctc
    44521 gtagcttggc accagctgtc ttggtaggcg gcgcagccct tcaacaagtt tggattttca
    44581 tccttgcacc aatcgctggt ggagttcttg cagcccttgt tgcaaaaaat ttccttggaa
    44641 cagaaaaata attgaaactc aaaaagcctt gctcctcatc ttgaggaaca gggctttttc
    44701 gtatgatact cttcgaaaat ctcttcaaac cacgtcagct ttaccttgcc gtaggtatgg
    44761 ttactgacta cgtcagttct atctgcaacc tcaaaacagt gttttaagct gacttcgtca
    44821 gttctatcta caacctcaaa acagtgtttt aagctgactt cgtcagttct atctgcaacc
    44881 tcaaaacagt gttttgagct gacttcgtca gtcttatcta taacctcaaa cactgctttg
    44941 agcaacctgc ggctaacttc ctagtttgct ctttgatttt cattgagtat gactttagcg
    45001 gttgtcaatt ttctctggat aaaggtcgtg ttggaagagg cgttgttctg ccaagtcctc
    45061 atacttagtt ccttgcttac cgtagttgta gtaggggtcg attgaaatgc caccgcgcgg
    45121 agtgaatttt ccccagactt ctaaatagcg agggtctagc aagttgacca agtctttccc
    45181 gatggtgttg atacagtttt cgtggaaatc tccgtgattt cggtagctaa atagatatag
    45241 tttgagggat tttgactcga cacagagctt gtcaggaatg taggaaatat gaatcgtcgc
    45301 aaagtctggc tgagcagtga tttgtcccag cagagacata tcgaggatat ggtgacgaat
    45361 gccctgttcc ttagcgattt ctctagcaat ttgaatttcg aggtgatgac gttggccgta
    45421 ggcaaaggtg acagcttcga ctgtttcata gtgttgcata acccagaaaa ggcaggttgt
    45481 tgaatcttga ccaccactaa agacgaccaa ggctgattga cgtttcatag tactccttcc
    45541 aaaatgggaa atgttcagag catgcaaaaa gctcctatta gggagctaaa aaataccaaa
    45601 tcgagttttt ttagcgatgg catatcccaa acatcgtaat attctactta tatagtaaaa
    45661 tgaaataaga acaggacaaa tcgatcagga cagttaaatc gatttctaac aatgttttag
    45721 aagtagaggt gtactattct agtttcaatc tactatagtc tagcatattt tttgaaaaat
    45781 ggcaaagggc aagaaaaaag agaccaaaga aagtacttgg tctctcgttt gattagctca
    45841 attcagcaat gatggccttg atttgttctg ctgtgtgaac acctgcaact tgtttgacaa
    45901 cttggccgtc ttttttgaag agaagagttg gaatagacat gattccaaaa gcacgagctg
    45961 tgtttggatt ttcatcaacg tccattttaa cgattttcaa gacatcttct gaaagttctt
    46021 cagacaattt gtccaagatt ggaccttgca tacgacatgg accacaccaa gttgcccaga
    46081 agtctactaa gaccaaacca tcttttgttt cttgttcgaa tgttgcatct gtaattgctt
    46141 ttgccattgt atttctcctt tttttagtta tattggctta aatcttgttt catgagatag
    46201 aagaagatat ctccataagt cccatggtag tccaaattat gacccttgta agttaatttt
    46261 tggacagggt agtagtctgc gacgccgata aggcaagctt gttgcgaacg ttcaaagtct
    46321 tcataagact cgaaagtcac agttctttcg ttcttgctgg catctatata ggtaatttca
    46381 atcatattta aaactccttt gtttaatgct aactttattt tactccttat aaaagagaat
    46441 gtcaagaaaa atgattgcgc acgcaacttt ttttaaaaat catcttaaat caagaaatcc
    46501 aaacctgctt ccaagctttc ttcgacagtc ttttgtagcg aggccagtgt cttttgccca
    46561 tcatttgtca ggcagataaa actagagcgt ctatcttgat ggcaacacat gcgactgagt
    46621 agaccgcaat ttttagcttc caagcgagcc accatcctag aaactgcgct cgggctcaga
    46681 tgaagtttat ctggcaggtc aatctggcgt agagattttt cttcagccaa gtccagatag
    46741 tagagcaggt agaactcttt caaggtcaga ctttgctcgc tctgttgggc aatggtctct
    46801 tccaagagac tttcaatttc tttctgacgc cgattgaagt caaaccattt ttccaaatag
    46861 gtcatagtgt ctcctttctt tttagagtca taaatagaag aaagtccatt aacgggcagt
    46921 ctctgcgtca caagatgatt gcgcatgcaa taattatact acttttcaag aatgctggca
    46981 agctctgttt tttagtggtt ttatttttta ctgtctatat ttttggtaaa aatcaacttt
    47041 tacttggatg aaggttttgg cttcacgtag gagttgaaga agggtggcgc gggtttcaaa
    47101 ttcttctctt gtcttgggca gactgcggtt ccggaagact tccagataac gttcaatttc
    47161 atctagcaaa tcagaagcag gattggtctg gctcagttga cctgcaattt ttgaaaagag
    47221 ttgcgctaag atcaggcttt cactggcggc aaggtgacaa gtgttaatct gttgggccat
    47281 gtttctcagg atacgacttt gtcgttgtct catctcaaag tagtggatat ggtagtcggt
    47341 ctggtgaaag aggtggtcag agtgatccaa atagaccagt ctgagggctt ctttcaaaag
    47401 cgtgtctaat tctgctacca gctgtgctcg gttgcgtccg tctcctctgg ataaatagta
    47461 tttgaagcgc tggaggatat cttttaactt ttcttccacc agcgtgtggt agtgctggat
    47521 ttcctcttct cgtgaaggca tatagagatt aacaagcaag gcaaatcctg taccaatagc
    47581 aaagagaagg aattcattga ctagaaggtc tggagaggtt gactcttgaa ccaagagatg
    47641 gctaaccaaa acagtgcttg gtgtgatgcc aatttcccag cccatcttgt aggctaaagg
    47701 aacgtagaag gccagataga ggccgagact ccagatatga aatccgctca agtgaaaagc
    47761 tagaacaccg atagccagag ctagaagcat agaaaaaaga cgattgcgag ccagttttaa
    47821 agtacttcta cgcgtatcag ataggctcaa gagagcgata attccagccg aaactgctga
    47881 tgaaagattg agaaaataag caagcaggca ggcaagacag gtagctaaga tgagcttggt
    47941 cgtacgttgg ctaatagaca taagaatttc ctaataagtt agaataaaag cgtaaaagac
    48001 aagacatgag caggcttgcc ttgatgagtt attttttacg ggttgctgcg tattcggcaa
    48061 cggcggtaaa gaggacatct gtagaagagt taagggctgt ttcacatgag tcttggatga
    48121 caccaatcac aaaaccaacc ccaacaactt gtatggcaat atcgttagaa ataccgaaaa
    48181 ggctacaagc aactgggata agaaggaggg aacctccggc aatacctgaa gcaccacagg
    48241 ctgagatagc tgctaccaca ctgaggacaa aggctgtggc aaagtcaaca ggaattccaa
    48301 gagtgttaac tgcagcaagg gtcaaaacgt taatggtaat cgctactcca gccatattga
    48361 tagtagaacc gagtgggata gaaacagaat aggtatctgg gttgagtcca aggtcatggc
    48421 agagtttcat gttgacagga atgttagccg cagaactacg agtgaaaaag gctgtcacac
    48481 cgctgacacg gaggcagttc caaactagag ggtaaggatt gcgtctcata aagaagaagg
    48541 caatcaaagg gtgaccacaa gggcaacaaa aagcatagtc gttactaata gaaccaataa
    48601 aataccgtag ttggtaaggc ttccgactcc cttgtcagaa atggttttaa aaacaagacc
    48661 aaggcttcca aatggagcca gattgatgat ccattcgaca attttagaag tcacgtcagc
    48721 gatagttttt agcaattctt tactattttt actggcttct ctcatagcga ttccaaaaat
    48781 gactgcccaa gataagattc taatatagtt agcagtaaac agggcgttga ctgggctgtc
    48841 aaccagtttg agcaagaggt tgctgagaac ctgcccaacc ccatctggtg gtgcaatttc
    48901 agtattggca ctatttaggg taatttcaat agggacgatg aaacttgcta gtacagctac
    48961 aagagcagcg gcgaaagtcc ctatcatagg atatacaaga aaacaacagt tttcatattg
    49021 ctatcttgtc ccttttgatg ttggaaaggg cattggcaac gagggcaaag actaggatag
    49081 gagcaacagc ttttagacct ccaacgaata aatccccgag tagcccaatc cctgagagat
    49141 taggaagggt cagtcctagg attccccaca aagcatacca atcaagatac gcttgacaag
    49201 gcttgcctta ttccaagcat gaatgattct tttcataata atctcctttt tgtgtagtga
    49261 ttatgattat agtataaatg atagacaaaa tcaagaattt tctgtctatt ttttgaatat
    49321 ttatggagaa tgagactgat gaaaatatgg tataatgaaa taaaggagtt ttatatgcaa
    49381 aaatttattc aggcttatat tgaaaagcta gatgtgacaa ccattatcga gaatattcta
    49441 accaaggtca tttctctttt actgcttttg attgtatttt atattgctaa aaaaatgctt
    49501 cataccatgg tgcagagaat tgtcaaacct tctctaaaaa tgtctcgtca tgatgtcgga
    49561 cgccaaaaaa ccatctcacg tttactagaa aatgtgttta attatacgct atatttcttt
    49621 ttactctact gcattttgtc gattttaggt ttgccagttt ctagtttgct ggctggagct
    49681 ggtattgctg gggtagcgat tggtatggga gcccaaggct ttctgtctga tgtcatcaat
    49741 ggctttttca tcctctttga acgtcaactg gatgtgggag atgaggtcgt tctgacaaat
    49801 ggaccgatta ctgtatcggg taaggttgtc agtgtgggaa ttcgtacgac acagcttcgt
    49861 agcgaggagc aagcccttca ctttgtccct aaccgaaata tcacagttgt tagcaatttc
    49921 tcacgcacag actagacctg ttattttaag taatttgtgg tacaatagag ggagtttaat
    49981 aaggagaaaa gatggtttta gaaaagcagt tgggcaatgg ttgtacctgg atagacctag
    50041 acctaggaaa gttgaataaa ctagaagacc tttctgaaat ttacggtttg gacaaggaaa
    50101 ccattgaata cgcactggat agaaacgagc gcgcccacat ggactaccac cgtgaaagtg
    50161 ggacggttac ctttatctat aatgtcctag acgtaaaaaa ggacaaggcc tactatgaga
    50221 cttttcccat gacctttatt gtcgagcatc gtcgcctgat taccattagt aataccaaga
    50281 acgcctatgt cattgaacag atgactcgtt atctggagag ccatgacacg ctttcgattt
    50341 ataagtttct ctttgccagt ctggaaatca tcagcaatgc ctactatcct gtcattgagc
    50401 agatggacaa gagtagggat gaggtcaatg acctcttgcg ccagcgaact accaagaaaa
    50461 acctctttgc cctgtctgat ttggagactg gtatggttta tctaacggca gctgccaaac
    50521 aaaatcggat tttgttagag catattcaag gtcatgcctt gtatcgtagt tttgatgaga
    50581 ttgagagaga acagtttgat gatgccatga ttgaggctca tcagctggta tccatgacag
    50641 acctaatctc tcagatttta cagcagcttt cagcctctta caacaatatt ctaaacaata
    50701 atctgaatga caatttgaca accttgacta tcatttcagt cttgctagct gttttggcag
    50761 tcgtgacagg ctttttcgga atgaatgttc ccttgccttt aacagatgag ccccatgctt
    50821 ggctctatat cagtttggct agtgcaggtt tgtggattgt tttatccttg ttactaagga
    50881 aaattgcgaa aaaaagttaa gaaaaggagc cagaatggcg attgaaaatt atataccaga
    50941 ttttgctgtg gaagcagtct atgatctgac agtcccaagc ctgcaggcgc agggaatcaa
    51001 ggctgttttg gtcgatttgg ataataccct cattgcttgg aacaaccctg atggaacgcc
    51061 agagatgaag caatggctac atgaccttcg ggacgcgggt attggcatta tcgtagtgtc
    51121 aaataacacc aaaaaacgcg ttcaacgagc agttgagaaa tttgggattg attacgttta
    51181 ctgggccttg aagcccttca catttggtat tgaccgtgct atgaaggaat tccactatga
    51241 caaaaaggaa gtggtcatgg ttggtgacca gctcatgaca gatatacgag cagcccaccg
    51301 tgcagggatt cggtcaattt tagtcaaacc cttggtccaa catgactcaa tcaaaacgca
    51361 gattaaccga actcgtgagc gtcgtgttat gagaaaaatc actgaaaagt acggaccgat
    51421 tacatataaa aaaggaattt aactatggaa gaaattctct gtattggttg tggagcaacc
    51481 attcagacga cagataaagc tggtcttggt tttacccccc agtcggcact tgaaaaaggt
    51541 ttggagactg gcgaagtcta ttgccaacgc tgtttccgtc tccgccacta caatgaaatc
    51601 acagatgtcc agttgacgaa cgatgatttc ctcaagctct tgcacgaggt gggagacagt
    51661 aatgccttag tggtcaatgt cattgatatc tttgatttta atggatctgt catcccaggt
    51721 ttaccacgtt tcgtctcggg caatgatgtc ctcttggtag gaaataaaaa agatatcctt
    51781 cctaagtcag ttaagtctgg taagattagc cagtggctca tgaaacgtgc ccatgaagaa
    51841 ggtcttcgtc cagtcgatgt ggtcctaact tcagcacaaa ataaacatgc cattaaggaa
    51901 gtcattgaca agattgaaca ctaccgtaag ggccgcgatg tctatgtggt cggtgtgacc
    51961 aacgttggaa aatcaactct aatcaatgct attatccaag aaatcacggg tgatcagaat
    52021 gtcatcacta cttcacgctt cccagggaca accttggaca aaatagagat tccgcttgac
    52081 gacggatctt atatttacga tacgccggga attatccacc gccaccagat ggctcactac
    52141 ttgacggcca aaaacctcaa gtatgtcagt cctaaaaagg aaatcaagcc taagacctat
    52201 cagcttaatc ctgagcaaac cctattttta ggtggtttgg gacgctttga ctttatagca
    52261 ggagaaaagc aaggatttac tgctttcttt gataatgaac tcaaactcca tcgtagcaag
    52321 cttgaaggag ctagtgcttt ctacgataag cacctgggaa ctcttctgac accaccaaat
    52381 agcaaggaaa aagaagattt cccaaggcta gtccagcatg tctttaccat taaagataag
    52441 acagacctag tcatctcagg cctaggctgg attcgtgtaa caggcatagc aaaagtcgcc
    52501 gtctgggcac cagaaggcgt cgccgtcgtc acacgaaaag caattattta aaacaaaatc
    52561 gctgagcgaa caaagtgagc tcatatagcg atagttattg ccgtggtgtg attgccaatc
    52621 tgtagattgg caaggggcac aattgagacc aaggctcaat tgtgaggtca ggaaatccat
    52681 ttttcaaaga tgaaatcttt ggaaaattag ttccgaccgt ccctcaccac ctaaaataac
    52741 tatccaaaaa caaggaagaa aattatgtca ttaacatcaa aacaacgtgc cttcctcaac
    52801 agccaggcac acaccctcaa acctatcatc caaatcggga aaaatggact caacgaccaa
    52861 atcaaaacca gcgtccgtca agctcttgat gcgcgtgaat taatcaaggt tactctctta
    52921 caaaacacag atgaaaacat ccacgaagta gctgaaattt tggaagaaga aatcggtgtg
    52981 gatacagtcc aaaaaatagg acgcatcttg attttgttta aacaatctag caagaaagaa
    53041 aatcgcaaga tttctaagaa agtcaaagaa atctaagacc gaaactccaa ataactgttt
    53101 ttatagagaa ataaagggga ctagcctatg acaatcgaac tattgactcc ctttaccaag
    53161 gtagagttgg agccagaaat caaggagaaa aaacgcaaac aagttgggat tttagggggg
    53221 aattttaacc ctgttcacaa tgcccatctc attgttgcgg atcaagtacg gcaacagttg
    53281 ggactggatc aagttcttct catgcctgaa taccaacctc ctcacgttga taaaaaggaa
    53341 accatccctg aacaccatcg tctcaagatg cttgagttgg caattgaggg gattgacggc
    53401 ctagtcattg aaaccattga gttggagcgc aagggtattt cctacaccta cgacaccatg
    53461 aaaatcttga cagagcaaca tccagatacg gattattact ttatcatcgg tgccgacatg
    53521 gttgactatc tgcctaagtg gtaccgaatt gatgaactgg ttgacatggt tcagtttgtg
    53581 ggggttcagc gtccacgcta caaggcagga acttcctatc cagttatctg ggtggacgta
    53641 ccgctcatgg atatctcgtc cagcatggtg cgggacttca ttgcccaagg tcggaaaccc
    53701 aactttctcc tacctcagcc agtgctagac tacatcgaga aggaggggct ctactgatgt
    53761 cctatcaaga ctatatcaac tgctcccgtg aggccttgtt ggaaaaaatg gcagagcttc
    53821 tacctgagaa acgtctaacc cattgtctag gtgtggagcg tgccgctatg gagttagctc
    53881 agcgctttgg tgtagatgtt gagaaagcaa gtctagcagg tcttcttcat gactatgcta
    53941 aaaagttgtc aaatcaggaa tttctagcct tgattgaccg ttaccagcta gaccctgacc
    54001 tcaaaaactg gggcaataat gtctggcatg gtatggtcgg aatttacaaa attcaggaag
    54061 atttggattt gcatgattct gaaattctgc gagccattga aattcataca gtcggagctg
    54121 gtcaaatgac agacctagat aaggtcatct acgtcgcaga ctatatcgag cacaatcgat
    54181 cctttcctgg agtagatgtg gcgcgtgaga ttgcaagtct atcgctcaat aaggcggtgg
    54241 cctacgaaac agctcgtacc gtggagtatc tagctcatca gggattcccc atctatcccc
    54301 aaacccttga aacctataac gcctttgtgc actatttgaa agaggactaa atgaagacgg
    54361 cttttataat cattgatgtt cagaatgttt tagtagaaac tgggttccag acaaaaagtc
    54421 tattggaaaa aatttcttat ttacaaaacc aggctagaag caagaatatt gaaattatct
    54481 atgttcaaca tattgagaac tctgaagctc aaacatcaga agattggcag ttatctgcgc
    54541 ttttaaatcg aaaacctgct gaaaaggtct ttcagaagaa gtataacagt attttcaaag
    54601 aaactggctt aaaagaatac ttggataaac aggggattga aaaattagtt ttatgtggta
    54661 tgcagacaga atattgtgtg gatacctctg tcaaggttgc ctttgaatat ggctatcagc
    54721 ttattgttcc agaaggtgct gtcacaacct ttgatgggga tgacattcca gcagaaacga
    54781 ttaatgaatt ttatgaggac atttgggagg agcgctttgc agatgtccta gattacaaac
    54841 atattttcta aaaagaggat taaatgaacg aaaaagaatt actagaacta gtcgtgaaag
    54901 cggctgatga gaaacgtgcg gaggatatcc ttgcacttga tgtacaagat ttgactagtg
    54961 tgacggacta ctttgtcatc actagctcaa tgaatagccg tcagttggac gctatcgcag
    55021 ctaatatccg tgaaaaagta gctcaagcgg gctttaaagg tagccatgtc gaaggcgatg
    55081 cagctggagg ctgggtctta ctggacctcg gtgctgttgt cgtgcatatc ttttcagagg
    55141 aaatgcgtgc ccattataat ctagagaagc tatggcatga ggcgaattca gtagatattt
    55201 cagaagctct tgcttagaag atgaactcag ttgtagtcaa ctgggtttct ttgcttattt
    55261 tagaaaaatt gatagaaagg taaagggcct cgtgtttgtt tcatttcgaa actgaacacg
    55321 agctaaaagc tgagataaaa agtaactttc tttgtatctg acgataggga agaaagtttc
    55381 ctatgtactc tttgctttta aggctctttg tatcttagaa aggatttgaa cccgtcctgt
    55441 aattatcgga aaatagatag ccttccttgg agctcggctc catcgtaagg ctcctaattt
    55501 tctatcgaat tacgggcgga cttggtatca tgttttatgg cgacttatga aacctttgcg
    55561 gctgtctatg atgcggtcat ggacgatagt ttatacgaca aatggacgaa tttttctctg
    55621 cgtcatttgc ctaagaccaa ggagagaaag aaactcttgg aactggcttg tgggacagga
    55681 attcaatcag tgcgcttctc tcaggctggt tttgatgtga ctggacttga cttgagtgcg
    55741 gatatgttga agattgcgga gaagagagca acttcagcca agcaaaagat tgcttttata
    55801 gaaggtaata tgctgaattt gtccaaggca gggaaatacg attttgtcac gtgttattcg
    55861 gactctatct gctatatgca ggatgaggtg gaagtagggg acgtctttaa ggacgtgtac
    55921 aatgcgctga atgaagaggg agttttcatc tttgacgtgc actcgaccta ccagacagat
    55981 gaagtattcc ctggctattc ctaccatgaa aatgcggaag attttgccat gctttgggat
    56041 acatatgagg acgaaactcc tcactccatc gtgcatgagc tgactttctt tatcaaggag
    56101 gctgacggtt cctttagtcg ccacgatgaa gtacatgagg agaggaccta tgagatcttg
    56161 acctatgata tcttgctgga acaggctgga tttaagtcct tcaaactcta tgcagacttt
    56221 gaggataagg agccaacaga aactagcacc cgttggtttt ttgtggcgca gaagtaaatc
    56281 aaatattgtt aatcttatgc ttaggaggta agggaaaatg aatataccaa taccatttgg
    56341 tgatattctt gaaaaagaag taattaccaa tatacctaaa atttatcaaa agttaaagca
    56401 aatttataac gacttacagt ttaaaacaga agaagagtta ggtgttgttt atcaagaata
    56461 tttacaattt acttataaaa aatattccac tgtaaaaaca ttgttgtata aaaatgaagg
    56521 gaaattttta tatgatttct atgagcatgt ttatttagat gataataatt cagatttaat
    56581 agaaacctct aacacagaat tgatttttga aaaaacatct aacgttattt tgacaggaac
    56641 gggtgggatt ggtaaatcaa tgcttgtaaa gcatattttt atcaatcaag tacaacaagc
    56701 tacatcaatt ccaattttta ttgaattaaa atcacttaat gaatctgatt tctcagaaaa
    56761 tgaattagtt gattttattt accaagaggt tcaaaatcat catttaaatt tagaaaagaa
    56821 atattttaaa gcgacattag aggctggaag atatacaata atttttgatg gtttagatga
    56881 ggttaatcct tcaaaacgtt cttggttgga caaagaaatt aaagaatttg taacgttata
    56941 caatagcaat agatatgttt tgtcgtcaag accgtctgag gaatttattg gttggaatca
    57001 gtttgctgag tatgagataa aaaaattaaa tagagagcaa gcgttatcct taattgataa
    57061 gttgaattat gatgagaaag taaaaaggcg tttctacaga gaattaaagg atcatttata
    57121 tgatactcat gaatcttttg cttctatccc actcctatta acaattatgt taatgactta
    57181 cgaagctggt gcttctattc caaataattt aactgatttt tataatcagg ccttttatac
    57241 attgtaccaa agacatgatg catctaaatc aggatacaaa agagaactaa aagcaaaatt
    57301 aactcctgaa gaatttcgaa atatattagc ctacattggt ttaaaaacat tctttgaagg
    57361 aaaagtagat ttcgatagaa ctacacttga tgaaataatt actaaatatt gttttaaaaa
    57421 taaccttgaa ttaaagacga atgatatagt ttatgatgcg actcatagtg cttgtatgat
    57481 gcttcaagaa ggcgttagtt taaaattctc tcaccgttca ttccaagaat actttgctgc
    57541 agtaggtgtt aatcagctag atgataaact ccaaaaacag atactaatta agtggtctga
    57601 agcagatagg aataatattg tagcacataa aacttttatg aatgcacttt ttaaaataca
    57661 gaaagaaagg acttacaaaa atttatgtat tccaatcata gaaagaatgg atgaaaagta
    57721 tagcagaatg ggggatatca cagagaaaat tgttacgtgt ttcaattact ttatctgtag
    57781 aaaagatagt agagaaaaca aattagaatt gcacttttta ctaacaaagg aagttcactt
    57841 ttattttagc ttgcaatttt taatatttgc taatctaggt attgatatat tatcaataag
    57901 tgattatgaa aatatagaaa aattagagtc tgatatagta tcaaattgga agataaatga
    57961 aagaaaatat tataacatgt tgaacgatga tgaaaaaact ttaataaata agtggataaa
    58021 tggctggtat tttagtagac acaattactt aaaagaatgg tcaattaaat tcattgagga
    58081 aacaactact caaaaacgga gcctacagaa tataattgac tcaatttgat actaaagaag
    58141 taggagatta ctatgaccat cacgggtatt atcgcggagt tcaatccttt tcataatgga
    58201 cacaaatacc tgctggatca agcggagggg ctgaaaatcg tggctatgtc agggaatttc
    58261 atgcagcgtg gagaacctgc tatcgtggat aagtggacac gagcccagat ggcgctggaa
    58321 aatggagcgg atctggtagt ggaattgccc tttttagtca gcgttcaggc ggcagatttt
    58381 ttcggtcaag gggccgtgga tatcttagct cggttgggca tagatagcct cgcttttggg
    58441 acagaagaag ttctagatta tcaaaaaatc gctgacttat acacagagaa aggtgctgag
    58501 atggagaaat ttgtggaaaa tctgcctgat tccctttcct atccccagaa aacccaagct
    58561 atgtggaagg aatttgctgg tcttgatttt tcaggtaata cccccaatca tgttcttgct
    58621 ctggcctatg ccaaggcagt tgcaggacga aatatcaagc tgcatccgat tcagcgtcag
    58681 ggggcaggtt accattctgt gaataaagat gtggactttg cctcggcgac agccctccgt
    58741 caacatcaga aggaccaaga tttcttagaa cgctttatgc cttctgttgc cctatttgag
    58801 caggccagta aggtgatctg ggaagactat tttcccttgc tccgctatca aatcttgtca
    58861 aatcccgacc taaccaccat ctatcaggtc aatcaagaaa tggctgtgcg cattaaagaa
    58921 gctattaaaa cagcccagtc tgtagaagag ttggtcgagg cggttgcgac caaacgttac
    58981 accaaggcgc gtgtcagacg cctattgacc tatattttgg tgcaggctag agaaaatgtc
    59041 ttgccagaag ccattcatgt ccttggattt actgaaaaag gcaggcaaca tctcaagtct
    59101 ctgaaaggac aggtcaatct agtcagccga attggcaaag aaccttggga tgctatgacc
    59161 caaaaagcag accagattta ccaactagga aagccaagta tagcagagca aaattttgga
    59221 agagtgccga ttagaataga aacaagctaa gtctaccgaa aggtaggctt tttgagattt
    59281 tttacgaata atactcttcg aaaatcaaat tcaaatcgcg tcaacgtcgc cttgccgtac
    59341 tcaagtacag cctgcggcta gtttcctagt ttgctctttg attttcattg agtataaata
    59401 gatagaaaag aaaatcttgt acaagttcct gacaatttct ttcttttcgt gtataatagt
    59461 ggaaaagagc taaaacgagg tatggttatg gaagcagtcc tttactcaac attccgaaat
    59521 catttaaagg actacatgaa gaaggtaaat gatgaatttg agcctttgac ggtggtcaat
    59581 aaaaatccag atgaggacat tgtagttctt tcaaagagcg aatgggacag tattcaggaa
    59641 accctgagaa tcgcccaaaa taaggagtta tcagacaagg ttttgcgagg aatggctcaa
    59701 gtccgtgctg gaagcactca ggtccatgtg attgaggagt gatgaatgct actcaagttt
    59761 acagaagatg cgtgggcaga ttattgctac tggcaaaacc aagataaaaa aacactaaaa
    59821 agaatcaata aattaatcaa ggatattcaa cgcgatccat ttacaggaat aggaaaacca
    59881 gagccactca aatatgatta ccaaggagcc tggtcacggc gtattgatgc agaaaatcgc
    59941 ttgatttata tgatggatgg agatagcgtg gctttcttgt cctttaaaga tcattactaa
    60001 gtctattgaa aggtaggctt tttctcaagt ctctactaaa ctactatttc taaacaacaa
    60061 gtttattttg gtaaatgtgt tccaaattcc ccaaaacata ttctatttta ggtttgtgaa
    60121 aatcactttt ttatggtaga atgtaaaaga atgtatgtca ttcggaataa caataaaatg
    60181 aggtaaaaac atggaaatca tgtcgcttgc gattgctgtt tttgccgtca tcattggttt
    60241 agtcattgga tatgtcagca tctcagctaa gatgaaatca tctcaggaag ctgcagagtt
    60301 gatgctttta aatgctgaac aagaagcaac taatttacgt ggacaagctg agcgtgaagc
    60361 ggatttactt gttaatgaag ccaaacgtga aagcaagtct cttaaaaaag aagcactatt
    60421 ggaggccaaa gaagaagcca gaaaataccg tgaagaagtg gacgctgaat ttaaatcaga
    60481 acgtcaagaa ctcaaacaaa tcgaaagtcg tttgacagag agagctacta gccttgaccg
    60541 taaggacgac aatttgacga gtaaagaaca aacacttgaa caaaaagaac aaagtatttc
    60601 tgatagagcg aaaaaccttg atgcgcgtga agagcaatta gaggaagtcg aaagacaaaa
    60661 agaagcagaa ctagagcgta ttggtgctct gtctcaggca gaagcacgag atattatctt
    60721 ggctcagaca gaggaaaact tgaccaggga gattgccagt cgcattcgcg aagctgagca
    60781 agaggtcaag gaacgttctg acaaaatggc caaggacatc ttggttcaag ctatgcaacg
    60841 tatcgctggt gaatatgtag cggagtcaac aaactcaaca gttcatctgc cagacgatac
    60901 tatgaaggga cgcattattg gtcgtgaagg tcgtaacatt cgtacctttg aaagtttgac
    60961 aggggtcgat gtgattatcg acgatacacc agaagtggtg accttgtcag gatttgatcc
    61021 gattcgtcgt gagattgccc gtatgactat ggaaatgttg ctcaaagatg gtcgtataca
    61081 tccagctcgt atcgaagagt tggttgagaa aaaccgtcaa gagattgaca ataagattcg
    61141 tgaatacggt gaggctgctg cctatgaaat tggtgcgcca aaccttcatc cagacttgat
    61201 gaagattatg ggacgtttgc agttccgtac ttcatatgga caaaatgttt tgcgccattc
    61261 gattgaggtt gctaagttgg ctggtatcat ggcgagcgaa cttggtgaaa atgcggctct
    61321 tgcccgtcgt gctggattcc ttcacgatat cgggaaagcc attgaccatg aggttgaagg
    61381 tagccacgtt gaaatcggta tggaattggc ccgtaagtac aaggaacccc cagttgtggt
    61441 gaatacgatt gctagtcacc acggagatgt tgaagctgag agcgtgatag cagttatcgt
    61501 cgctgcagca gatgccttga gcgcagcccg tccaggtgct cgtagtgagt ctcttgaaag
    61561 ctacatcaag cgtctccatg atttggaaga aattgctaac ggctttgaag gagtgcaaac
    61621 tagctttgcc cttcaagcag gacgtgaaat tcgtatcatg gtcaatccag gaaaaatcaa
    61681 ggacgacaaa gtcacaatct tggctcacaa agttcgtaag aaaattgaaa acaatctcga
    61741 ttatccagga aatatcaagg taaccgtgat tcgcgagctt cgtgcagtag attatgctaa
    61801 ataaataaga aagagcagtt gaaaaattac tgcttttttg ttacactaga tagaaagact
    61861 gtaaaggata atctggcttt ttgccattat tctagagaaa tgttatttca cagattgact
    61921 aaaaggagac acaatggcag accgaggctt actaatcgtt ttttctggtc cttcaggggt
    61981 tggaaaagga acggttagaa gagagatttt tgagagttct gaaaaccaat ttcaatactc
    62041 tgtatcgatg acgacacgcg cacaacgtcc tggagaagtg gacggtgttg actatttctt
    62101 ccgtactcgt gaagaatttg aagagctgat tcgtcaagga cagatgttgg aatacgcaga
    62161 atatgtcggc aactactatg gaactcctct gacctatgtc aatgaaacct tggacaaggg
    62221 aatcgatgtt ttccttgaaa ttgaagttca gggtgctctt caggtcaaga aaaaggttcc
    62281 agatgctgtc tttatcttcc tgacaccacc agatttggat gaattgcaag atcgcttggt
    62341 aggtcgtgga acagatagtg cagaagtgat tgcccaacga atcgaaaagg ccaaggaaga
    62401 aattgccctc atgcgtgagt atgattatgc gattgtcaac gatcaggtgc ccctagctgc
    62461 tgaacgtgtc aaatgtgtga ttgaagcaga acacttctgt gtggatcgtg tcattggtca
    62521 ctatcaggag atgttaccaa aatctccaac tacccgataa aatttagaaa ataggtacaa
    62581 gcaaatgatg ttaaaaccct ctattgatac cttgctcgac aaggttcctt caaaatattc
    62641 actcgtaatc ttggaagcaa aacgtgccca cgaattggaa gcaggtgccc cagcaactca
    62701 aggtttcaag tctgaaaaat caactcttcg cgctttagaa gaaatcgaat caggaaacgt
    62761 tacaattcac ccagatccag aaggaaaacg tgaagcagtg cgtcgccgta tcgaagaaga
    62821 aaaacgccgc aaagaagaag aagaaaagaa aatcaaagag caaattgcta aagaaaaaga
    62881 agatggtgaa aaaatttaag gttgggggga ctcaatctta ttttttctat tgcaagaatg
    62941 tactgacaag gaggaggtga gaagatggcc ctagctaaga ttatcgtaga tgtgcccttg
    63001 atgcagacgg accagcccta tagttacagg attccggagg aatttgaggg aatgctggaa
    63061 gttgggatgc gggttcatgt gccttttggt aaggggaatc gcctgattca agggattgtt
    63121 cttggtttga agtcccaatc agatggagaa gagatggagc aagatttaaa agatattgca
    63181 gaggtgctgg atttttctcc tgttctcacg ccagaacaac tctggctggc tgaggagtta
    63241 cgcaaatctg tcttctccta caaaatctct atcctcaagg ccatgcttcc agggtttctg
    63301 aattctagct atgacaagat tctctatcct ctggaaggct tgagtcagga agaacgagta
    63361 cgcctgtttg gttcagaaga ttcgctagcc ttttcttcac tagaccttgc caagcaagct
    63421 gaaatgatgc gtttgactag aaaaggcctg cttggtctgg aatatcaggc agtcgatcaa
    63481 aagaaggtca agacccagtc ttggtatgag gttgaccatg cccaattaga aggtgttgag
    63541 atttctacac gtgccaagaa aaagttggaa ctgagagatt atctgctgtc tcatccagag
    63601 agcgcttcct tggctagctt gttagagtcc tactcgcgag agcaagtcaa cttctttgtg
    63661 gatcaaggtg ctgttaccat agtccaaaag gaagttcaac gctcggctgc ttattttgaa
    63721 ggaattgaag caagtagacc tttggagtta aatccagaac aaagacaggc gcgtgatgcg
    63781 gttgtgagtt ctattggcag ttctcaacct ccctttctac ttcaagggat tacaggaagt
    63841 gggaagaccg aggtttactt gcagattatc caaggtgccc tggataaggg taagacagct
    63901 attttgctgg tacctgagat ttccttgact cctcagatga ccgagcgttt tatagcacgt
    63961 tttggggaca aggtagccat tcttcactca ggattatcca atggcgaaaa gtatgatgaa
    64021 tggcgcaagg tggagcgtgg cgatgcccaa gttgttgttg gtgccagatc tgctatcttt
    64081 gctcctctga aaaatctggg tgtcatgatt attgatgaag agcatgaagc ggcttataag
    64141 caggacagca atccccgtta ccatgccaga gaggtagcta ttttacgggc tcagtataat
    64201 caagcaactc tggtacttgg atctgcaacg ccgagcttag agagccgggc acgtgctggc
    64261 aaaggcgtct atcaacactt acgtctaacc caacgtgcca atcctttggc tacaatccct
    64321 gaggttcaag tgattgactt tcgagactat atcggacaaa atgagacgtc aaactttacg
    64381 cctcctttgc tagaggctat ccaagaccgt ctggttaaaa aagagcaggt ggttctcatg
    64441 ctcaatcgcc gtggttattc tagctttgtc atgtgtcggg agtgtgggac ggtggatact
    64501 tgtcccaact gcgatatttc tctgaccttg catatggata ccaagactat gaactgccat
    64561 tattgtggtt tctcgaagga tattcctcag gtctgtccta actgtaagag ccgcagtatt
    64621 cgttactatg ggacgggaac tcagaaggct tatgatgagc tagcagaact ctttccccaa
    64681 gctcgcattt tgaggatgga tgtggatacg actcgaaaga aaggcagtca ccaagccttg
    64741 cttgaccagt ttgggcgagg ggaagcggat attttacttg gtactcagat gattgcaaag
    64801 ggtttggatt ttcccaatgt taccctagtc ggagttctaa atgcggatac ggccttgaat
    64861 ctgcctgatt tccgttcttc tgagagaacc ttccagctct tgactcaggt ggcaggtcga
    64921 gcaggtcggg ctgaaaaagc aggtcaagtc ttgatacagt cctacaattc gcagcactat
    64981 gctattcgat ttgccaagga tcaagattac gaaggctttt atgcctatga aatgggaatc
    65041 agacgacaac tcggctatcc accttactat ttcacgattg gtattaccct ttctcacaag
    65101 aaagaagaag aggttttcaa acgtgcctat gaagtcatga acattttgcg gtcaggcttg
    65161 tcagagacca gtcccattct ggggccaacg ccaaaaccga ttgcccgtac ccacaacctc
    65221 tatcattacc agattttaat taaataccgt ttagaagatg agctggggcc gaccctcaac
    65281 caggtcttgg ccttgactca agaacgggaa aatagtgagc tccgtctcag cattgaccat
    65341 gagccgcagc aatttttata agaaggagaa gatatgacaa aactaatctt tatggggacc
    65401 cccgactttt cagcaacagt cttaaaagga cttttgacag atgaccgtta cgaaattcta
    65461 gccgttgtga cccagccaga ccgtgctgtt ggtcgtaaaa aagttatcca agaaacccca
    65521 gtcaagcagg ctgccaagga agcaggacta tctatctacc aacctgaaaa attatctgga
    65581 agtccagaga tggaagatct tatgaagcta ggagcagatg gaattgtgac tgctgctttt
    65641 gggcagtttc tcccaagcaa actccttgat agcatggact ttgctgtcaa cgttcatgcc
    65701 tccctccttc ctagacaccg tggtggtgcg cctatccatt atgccttgat tcaaggggat
    65761 gaggaagctg gtgtgaccat catggaaatg gttaaggaaa tggatgcagg agatatgatt
    65821 tctcgtcgca gcattccgat cacagatgag gacaatgttg gcaccttgtt tgaaaaattg
    65881 gcgctagttg gtcgtgattt gcttttggac actctgcctg cctatattgc tggtgatatc
    65941 aaacctgaac cgcaggatac gagtcaggtt accttctctc caaatataaa gccagaggaa
    66001 gaaaaactgg actggaacaa aaccaatcgt caactcttta accaaattcg tggaatgaac
    66061 ccctggcctg ttgcccatac tttccttaag ggcgaccgct ttaagattta tgaagcccta
    66121 ccagtagaag gtcagggaaa tccaggtgag attctctcta tcggcaagaa agaattgatt
    66181 gtcgcaacgg ctgaaggggc tctatccctc aaacaagtgc agccagctgg taagcctaag
    66241 atggacattg cttccttcct caacggagtt ggacgtacat tgactgtagg agaacgattt
    66301 ggtgactaaa gtagaaacgg ctagaagttt agctctagca gtgctagagg atgtttttgt
    66361 gaatcaagca tattcaaata ttgccttaaa taaacacctc aaggggagtc agctttctgc
    66421 agcagacaag ggcttagtga ccgagctagt ctatggaacg gtagcccgta aactgactct
    66481 ggaatggtac ctatcccact ttatcgaaga cagagaccag ttagacagct ggctctatgt
    66541 ccttcttctc atgagtgcct accaactccg ctatttggac aagattccag atcatgctgt
    66601 ggtcaatgaa gcagtggaat tggccaaact ccgtaaaaaa ggcagtgaaa aattggtcaa
    66661 cgctgtcctt cgccgtatct tgcgtgaagg ctggccagat attgctagca tcaagcgaaa
    66721 aaacaagcgt gactccattg cctattctct cccagtttgg ctagttacca aactcaagga
    66781 agaatacgga gaggagagag caaaagccat ctttgaaagc ctgttagtgc gaaacaaagc
    66841 cagtattcgt gtaacagacc taagtcgaaa agaggaaatc caagccttgt tggaggcgaa
    66901 taattccctt ttagcaacca ctggtctggt taaggagcaa gggcattttg cagggcataa
    66961 tttgtttgcg gatggagcca ttaccatcca agacgagtcc agtcagctgg ttgctccgac
    67021 gcttgattta caaggtgatg agcgagtgct tgatgcctgt gcggctccag gtgggaaaac
    67081 agcccatata gcctcttatc ttacgacagg tcaggttact gctctggact tgtacgacca
    67141 caagttggat ttaattcaag aaaatgccca acgtctggga gttgaagatc gggttcaaac
    67201 tcaaaaattg gatgccagaa aggtgcatga gttttttgac caggattcct ttgataagat
    67261 tttggtggat gctccttgtt caggaatcgg tcttttgcgc cgaaaaccag atatcaaata
    67321 caataaagaa acggcagatt tcgcgtcctt gcaggaaatt cagttagaaa tattaggtag
    67381 tgtttgtcaa atactaggca aaggtggtat aataacttat agcacctgca ctatcgtctc
    67441 agaggagaat tttcaagtcg ttaaggcctt tttagagagt catcccgagt tcgagcaggt
    67501 aaaactagaa catgaatgta aggatatcat gaaagacggc tgtatcctca ttacacctga
    67561 attgtatgga agtgatggat tcttcatcag tcaatttcgc aagatatcgg attaggaagg
    67621 aactgacaca tggaaatttc attattaaca gatgttggtc agaaacgaac aaataaccaa
    67681 gactatgtca accactatgt caatagagct ggacgtacca tgattatttt agctgatggg
    67741 atgggaggtc atcgcgcagg gaatatcgct agtgaaatgg cggtcacaga cctgggtgta
    67801 gcttgggttg atacccagat cgatacagtc aatgaagtgc gtgaatggtt cgcccattac
    67861 ctagaaattg aaaatcaaaa gattcaccag cttggtcagg atgaagctta cagaggcatg
    67921 ggaactactt tggaagtcct tgctattatt gataatcagg ctatctatgc tcatattggt
    67981 gattcgcgta tcggcttgat tcgtggagaa gaataccatc agttgacgag cgatcattcc
    68041 ttggttaatg aattgctcaa ggctggtcaa ttgacaccag aagaggcaga agctcatccg
    68101 caaaaaaata ttatcaccca gtctattggg caaaaagatg aaattcagcc tgattttggg
    68161 acagttatcc ttgagtcagg tgactatctc ttgctcaata gtgacggctt gaccaacatg
    68221 atttcaggca gtgagattcg tgatattgta accagtgata ttcctttagc agataaaacg
    68281 gagacacttg ttcgttttgc taacaatgca ggaggtttag acaacattac ggttgccctt
    68341 gtttctatga acgaggagga tgcagaatga tccaaatcgg caagattttt gccggacgct
    68401 atcggattgt caaacagatt ggtcgaggag gtatggcgga tgtctaccta gccaaagact
    68461 taatcttaga tggggaagaa gtggcagtga aggttctgag gaccaactac cagacggacc
    68521 cgatagctgt agctcgtttt cagcgtgaag cgagagctat ggcagatcta gaccatcctc
    68581 atatcgttcg gataacagat attggtgagg aagacggtca acagtatctt gcaatggagt
    68641 atgttgctgg actagacctc aaacgctata tcaaggaaca ttatcctctt tctaatgaag
    68701 aagcagtccg tatcatggga caaatcctcc tagccatgcg tttggcccat accagaggaa
    68761 ttgttcacag ggacttgaaa cctcaaaata tccttttgac accagatggg actgccaagg
    68821 tcacagactt tgggattgct gtagcctttg cagagacaag tctgacccag actaactcga
    68881 tgttgggctc agttcattac ttgtccccag agcaggcgcg tggttcgaag gcgactgtgc
    68941 agagtgatat ctatgctatg gggattattt tctatgagat gttgacaggc catatccctt
    69001 atgacgggga tagcgcggtg accattgccc tccagcattt ccagaaaccc ctgccgtccg
    69061 ttattgcaga aaatccatct gtacctcagg ctttagaaaa tgttattatc aaggcaactg
    69121 ctaaaaagtt gaccaatcgc taccgctcgg tttcagagat gtatgtggac ttgtctagta
    69181 gcttgtccta caatcgtaga aatgaaagta agttaatctt tgatgaaacg agcaaggcag
    69241 ataccaagac cttgccgaag gtttctcaga gtaccttgac atctattcct aaggttcaag
    69301 cgcagacaga acacaaatca atcaaaaacc caagccaggc tgtgacagag gaaacttacc
    69361 aaccacaagc accgaaaaaa catagattta agatgcgtta cctgattttg ttggccagcc
    69421 ttgtattggt ggcagcttct cttatttgga tactatccag aactcctgca accattgcca
    69481 ttccagatgt ggcaggtcag acagttgcag aggccaaggc aacgctcaaa aaagccaatt
    69541 ttgagattgg tgaggagaag acagaggcta gtgaaaaggt ggaagaaggg cggattatcc
    69601 gtacagatcc tggcgctgga actggtcgaa aagaaggaac gaaaatcaat ctggttgtct
    69661 catcaggcaa acaatccttc caaattagta attatgtcgg ccggaaatct tctgatgtta
    69721 tcgcggaatt aaaagagaaa aaagttccag ataatttgat taaaattgag gaagaagagt
    69781 cgaatgagag tgaggctgga acggtcctga agcaaagtct accagaaggt acgacctatg
    69841 acttgagcaa ggcaactcaa attgttttga cagtagctaa aaaagctacg acgattcaat
    69901 tagggaacta tattggacgg aactctacag aagtaatctc agaactcaag cagaagaagg
    69961 ttcctgagaa tttgattaag atagaggaag aagagtccag cgaaagcgaa ccaggaacga
    70021 ttatgaaaca aagtccaggt gccggaacga cttatgatgt gagtaaacct actcaaattg
    70081 tcttgacagt agctaaaaaa gttacaagtg ttgccatgcc gagttacatt ggttccagct
    70141 tggagtttac taagaacaat ttgattcaaa ttgttgggat taaggaagct aatatagaag
    70201 ttgtagaagt gacgacagcg cctgcaggta gtgcagaagg catggttgtt gaacaaagtc
    70261 ctagagcagg tgaaaaggta gacctcaata agactagagt caagatttca atctacaaac
    70321 ctaaaacaac ttcagctact ccttaaaagt agatggataa tcaaaatgag taatcaatct
    70381 ttgtcatgat ttcatggcaa agattttttt tgagtccaga tttgtgatag aatagaggga
    70441 gttgataaaa ggaggaaagc atggaagaat caaaagaatt aaatgccgtc attgatgtga
    70501 ttatgctagc ggggactatt ctccttaaaa gtggctcaga aatccatcgt gtagaagata
    70561 ccatgattcg aatcgcgcat tcgcagggga ttgtggattg caatgtcctt gccatgcctg
    70621 ccgctatctt tttctctatt gaaaatacca atatttcgcg catgaagcgc gtgacctcct
    70681 cttcttataa catcgaaaaa gtctgcgatg tgaaccagat ttctcgtcag ctggttgggg
    70741 ggcagattga tttagaaaca gcctttaagc aattgacggc cttgcaagct caaccccttc
    70801 cctatactaa gttgcaggta actctggctg cgacctttag tgctcctttc ttttcaatta
    70861 tgtttagcgg aaatatctac gacgcacttg gggcaggagt ggcgacctta tttggttttg
    70921 ccttttccct ctatgtggaa aaatttatcc gaattccctt tgtgacagcc tttgctggag
    70981 cctttgtctt tgggataatt gcccagtttt gggctcgcta cacaggtttt ccttcaacgg
    71041 cagatttgat tatagctggt gcggtcatgc cgtttgtacc aggtattgcc ttgaccaatg
    71101 cggtccgtga tattatgacc aaccacataa actctggtat gagtaagatg tttgaatccc
    71161 tgctcattac cctcgcttta ggggcaggaa cttctgtcgc cttggtattg atgaactaat
    71221 atgacactaa caaccttttt attacaagca gtagcaagtt ttcttgccat tatcactttt
    71281 ttaatcgtac tcaatgtgca acggtctatg ctcttacctg gagggatttt gggcatgact
    71341 gtctggctaa tctatctctt gctcaaggaa ccgaccaatg tcattgtagc taccttcatt
    71401 gcagccatta ttggttcttg tgtcagccag attttaagta ttctttataa gacacctgct
    71461 gtggtcttta tcttggccat tttggcaccg ctggttccag gttatctctc ctaccgaaca
    71521 actgcctttt ttgtgacagg ggactataat aaagcactgg caagtgcgac cttggttgtc
    71581 atgttggctt tggtaatctc tattggaatg gctagcggaa cagtgattct cagactgtat
    71641 cattatataa aaacacatcg agtatcgtag actttacaga aataaaagaa ttttctgaaa
    71701 aatgagataa ataaattaac aacgctttct atatgtgcga gaataccgca cttatgaaga
    71761 aattgcggct gattttggta tccacgaaag caacttaatc cgtcggagcc aatgggttga
    71821 agtaactctt gttcaaagtg gtgttacggt ttcaagaact tctctcagtt ctgaggacac
    71881 ggtgattgtg gatgcaacag aggtaaaaat aaatcgtcct aaaaaaagaa ttagcgaatg
    71941 attctggtaa aaagaaatgc cacgctatga aggctcaggc gattgtcaca agtcaaggga
    72001 gaattgtttc tattgccatg atatgaagtt gttcaaaatg agtcgcggaa atatcggaca
    72061 agctggtaaa atcttggctg acagtggtta tcaagggccc atgaagatat atcctcaagc
    72121 acaaactcca cgtaaatcca gcaaactcaa gccgctaaca gctgaagata aagcctataa
    72181 ccatgcgcta tctaaggaga gaagcaaggt tgagaacatc tttgccaaag taaaaacgtt
    72241 taaaatgttt tcaacaacct atcgaaatca tcgtaaacgc ttcggatcac gaatgaattt
    72301 gattgctggt attatcaatc atgaactagg attctagttt tgcaggaagt ctattatttt
    72361 ccttattgtc tgtaagtcta ctgaccttgt tgtttatccc agtcatggtt tctagttcgg
    72421 gctcagagtt tcaaagtgga tggcaagagc atcaattgat tgctgagaag gttagtaaaa
    72481 cacttgacaa gacatttgat aaggatgtca gagaaattcc gaccagtcag ttttatcaaa
    72541 aatttgtaga tgagatggga aggacttact caggaaattt gatcctccag gagctgataa
    72601 ctgtgaatgg agcttataaa gctacttata tcggtgaact ctctagcaac taatcattct
    72661 ttaaaatgat gaccaataag aggcttgatt tggtgaatca agtctttttt ctctctttta
    72721 ctgccatttg tgataaaata gtatagaacg attttttaca tgaatgataa aacagaggta
    72781 aatatgacaa tcggtattga taagattggt tttgcgacca gtcaatatgt cttgaaatta
    72841 caagacttag cagaagcgag gggaattgac cctgaaaaat taagtaaagg actcttactc
    72901 aaggaattga gtattgcgcc cctaactgag gacatcgtga ccttggcggc cagtgctagt
    72961 gactctattt taactgagca agaaagacaa gaagttgaca tggtcattgt ggcgaccgag
    73021 tcaggaattg accagagtaa ggctgcggcc gtctttgtgc atggcttgct gggcatccag
    73081 ccctttgctc gtagtttcga gattaaagaa gcctgctatg gggcgactgc tgccctccat
    73141 tatgccaaat tgcatgtgga aaattctccg gagtccaagg tcttggtcat tgccagtgat
    73201 attgccaaat acggtattga aactccggga gaacccactc agggtgccgg aagtgtggct
    73261 atgttgatta cacaaaatcc acgcatgatg gcctttaata atgacaatgt agctcagacc
    73321 cgtgacatca tggatttctg gcgaccaaat tactcgacaa ctccttatgt aaatggtgtc
    73381 tattctaccc aacaatactt ggatagtttg aaaacgactt ggcttgaata tcaaaaacgc
    73441 taccagctta ctttggatga ttttgcggct gtttgtttcc acttgcctta tcctaaatta
    73501 gcgctaaaag gcttgaaaaa aatcatggat aagagcctgc ctcaagagaa aaaagacctc
    73561 ttacaaaagc attttgacca gtctattctc tacagtcaaa aggtggggaa tatctacaca
    73621 ggttcacttt tccttggact tttgtctctc ttggaaaata cagatagctt gaaagctggg
    73681 gataaaatcg ccctttatag ttacggaagt ggagctgtgg ctgagttctt cagtggtgaa
    73741 ttggttgaag gatatgaagc ttatttggat aaagaccgct tgaacaagct caaccaacga
    73801 actgccctat ccgttgcaga ctatgaaaag gtcttttttg aggaagtaaa cttggatgaa
    73861 acaaactctg cccagtttgc tggctatgaa aatcaagatt ttgccttggt tgaaattctt
    73921 gaccaccaac gccgttatag caaggttgaa aaataatgaa gataagttgg aatggatttt
    73981 ctaaaaaatc ataccaagag cgcctcgagc tgctaaaagc tcaggcgctc cttagtcctg
    74041 agagacaagc tagtctggag aaggatgaac agatgagtgt gactgtggca gaccagctga
    74101 gtgagaatgt ggtgggaact ttttctctgc cttattcgct ggttccggag gtacttgtca
    74161 acggtcagga atacaccgtt ccctatgtga cagaagaacc ctctgtggtt gcggcggcca
    74221 gctatgccag caaaatcatc aagcgtgcag gtggttttac tgcacaagtc catcagcgac
    74281 agatgattgg gcaggtagcc ctttatcaag ttgctaatcc taaactagcg caagagaaga
    74341 ttgccagcaa gaaagcggag ctcttggagc ttgccaatca agcctatcct tctatcgtta
    74401 aacgtggagg tggggcgcgt gatctgcatg tcgagcagat aaaaggtgaa ccagactttc
    74461 tcgttgttta tattcatgtc gatacccagg aagccatggg tgccaatata ctcaacacca
    74521 tgctggaagc cttgaaacca gtcttagaag aactcagtca gggacagagt ctcatgggaa
    74581 tcctgtccaa ctacgcgacc gattctctgg tgactgcaag ctgtcgcatc gcctttcgct
    74641 acttgagccg ccaaaaggat caaggacgag agattgcgga gaaaattgcg ttggctagtc
    74701 agtttgcgca ggctgatcct taccgagctg ctactcataa taaaggaatt tttaatggta
    74761 ttgatgcgat tttgattgcc actggtaatg actggcgtgc catcgaagct ggggcccatg
    74821 cctttgccag tcgagatgga cgctatcaag gtcttagctg ctggacgctg gaccttgaaa
    74881 gagaagaatt ggtcggtgag atgaccctgc ccatgcctgt agcgactaag ggtggctcta
    74941 tcggcctcaa cccacgtgta gctctcagtc atgatctact aggaaatcct tctgccagag
    75001 aattagccca gattatcgtg tccatcggtc ttgctcaaaa ttttgcagcc ctcaaagcct
    75061 tggtaagtac gggcatccag caaggccaca tgaaactaca ggccaaatcc ctagctctcc
    75121 tagctggggc tagtgaatct gaagttgctc ccctagtaga gcgcctcatc tcagataaaa
    75181 cctttaacct agagacagcc cagcgctatc tcgaaaattt aagatcataa aaaactcaga
    75241 cgaatcggtc tgagttttct tgtgtttaaa tactttttcc tggtaatagt gtaactggta
    75301 agaagtaacc agttgtggcg acttccttgc cttcaatctt ttgcaagaga agatcaatag
    75361 tgagacaagc aatctcttcc aaaggttgct tgatagtagc caattgaggg tagtaatttt
    75421 cgataaagta ggtcccatca tagccgatga ccttgagctc ttttgggaca gaaatgccca
    75481 attcttgagc gattttaatg accagaatag ctgtcaaatc atccgaagca aaaatggcat
    75541 ctggtttttc ccgggtcaag atattcttga tttccatttt ttttctgacg ggagaaaagt
    75601 cactggaaac attgataata ggagcttttg ggagtacgga tgcaaaacca gcgtggcgca
    75661 gtccggttgg cgaattggaa ttgtcattcc ctgtaatcat gatgatagac tgggcacctg
    75721 tcttgaccaa ggtttgggca gcaagaaccc caccagcata gttgtcagag gagacgacag
    75781 ggatgtctgg cgataggttt cggtcaaagg aaataatcgg cgctgtcaca cgattgtagt
    75841 cttcgattcc taggttgtga ctaccagaaa tgatgccgtc cacctgattg gcttccaaca
    75901 tttcgatata ttcgcgttcc ttctcagaat catgttcact gttgcagatg atggtcttgt
    75961 aaccattttt gaagagttgg tgttccaatt tatcaatcaa ttctgcatag aaaacattgg
    76021 aaatattagg gaaaatcaag ccgattaact tagctgattt tccttgcaga ctacgagcca
    76081 ggttgttggg tttatagccc aattctcgca tggcttcatt gactttttgg atggttttct
    76141 cagatagata ccctttttta ttgataaccc gagaaacggt agtaggactg acgcctgcaa
    76201 gtttggcgac atcagttagt tttgcgacca taatctaatt catagtaaat tccagttggg
    76261 tttccagatt tgatcaggat accattttgg tccgcatgtg ggaagacacg accagaaaat
    76321 actttttctc ctttattgat gaaaatttca aagacagagt tatcgatgaa gattgtagca
    76381 gtagtagcct gattctcgat agggcaagaa cgagttgtcc caaattcttg ggcatactgt
    76441 tctccagcct ggctacgatc cactgtcact tgaccgttta caaggtcaaa gttgattgaa
    76501 agtcccttac cttctttatc agcaagtaag acaatctcgc tctggctatt agcttccaag
    76561 ttgagttcaa gttcgtaagt gttcttggtt tgggaacggt ttgagaaggc ttcttcagaa
    76621 gcacgaaggt ccttaatagc agcgactgga tactggtaga gcttgtcgtc tttgatagtg
    76681 agttccttga ccaaagagaa ggttccttgg tgatcaaaac agtcagatgg gtaagaaaca
    76741 tctggcaaac caagccagct aactgctaga gcacgcccat caggagcgtt gaaggcttga
    76801 gttgcatagg cttcgaaacc gtaatccatg ttttgaagtt gagacacatc taccattttg
    76861 gcatttttag ggtcaaagga agccccaatc ttatacatat ttggaaagat attatcgtag
    76921 tctagaactt tcttatccaa tccttgtgga cagtagagaa ggacaggctg ttcctctaca
    76981 aagaccagat taggacattc catcatgtag gcagtacggt cgttagcaaa gtcaaggtcg
    77041 ccaactgctt gccagtttgt gtagtcgtta ttgacagcct tgtagagacg gacgaagcct
    77101 tttttctcca agtcctgtcc accgacgaca gcatagtatt gacctttaaa gttaaaaatt
    77161 tgtggatcgc ggaagtggtc agtagagtct gctggctggt caatcaagat cttgtcaatc
    77221 tttgtaatct taccctcctt gtccatcaaa gcaccgatct ggtatgggtg acggatccag
    77281 ttttcatcgc gaacatttcc tgtataaaat aggaataagt tatcgccaaa ttgcatggca
    77341 gaaccagagt aggcaccgtg gctatctaat ggagtatctg gtaaaacttt gattccagtt
    77401 tctttaaagt gaatcaaatc atcactttct agctgtgccc aagattttaa accgtgggct
    77461 gcaccaaaag gaaaattctg gtaaaagagg atccacttgc catcaaagta agaaaagcca
    77521 tttgggtcgt tgagaagtcc tgtttttggc tcaacatggt aatgagtatg ccatggagat
    77581 tgtgccatat tttcctttat atgttgaatt tcttcttgcg tccaatcttg ataaagtctg
    77641 taacgacgct cagttgtcca ttccattcat tcctccaaaa atcttatcac ttttaatagt
    77701 aactgttttc gataaaaaat gcaagccttt tatgttaaaa aagagaaaaa actgtcaaac
    77761 gattatcata aaataaatac aggaaatcaa tcaatttttt acgaaaatgt gaaagataat
    77821 gaaataaaag actttttaac caaggtttca aacttatttt tcaaggaatt cctgatgaaa
    77881 cagtcaaaaa caatcaatct aaagcttgcc cattaagtgg atagaatatt ttttctgcaa
    77941 aacgcttgac atatttttaa aacatgataa aataatagtc gtaagggcga ataaaatcgc
    78001 tttcaaacaa gaacaaaatg ttatataagg agatttttgc aaatgaacaa tcaggaaatt
    78061 gcaaaaaaag tcatcgatgc cttgggcgga cgtgaaaatg tcaatagtgt tgcccactgt
    78121 gcgactcgtc tacgtgtcat ggtcaaagat gaagagaaaa tcaataaaga agtgattgag
    78181 aacttggaaa aagttcaagg tgctttcttt aactcagggc aataccaaat tatctttggt
    78241 acaggtacag ttaacaaaat gtacgatgaa gttgttgtac ttggcttacc aacatcatct
    78301 aaggatgaca tgaaagcaga agttgctaaa caagggaact ggttccaacg tgctatccgt
    78361 actttcggtg atgttttcgt tccaatcatc ccagttatcg tagcgacagg tctcttcatg
    78421 ggtgtgcgtg gtcttttcaa cgctcttgaa atgccacttc caggtgactt tgcaacttac
    78481 acacaaatct tgacagatac agccttcatc atcttgccag gtttggttgt gtggtcaacc
    78541 ttccgtgtat ttggtggaaa tccttccgtt ggtatcgttc ttggtatgat gcttgtctct
    78601 ggctcacttc caaacgcttg ggcagttgct caaggtggtg aagtaacagc gatgaacttc
    78661 tttggtttca tccctgttgt tggtttgcaa ggttccgttc ttccagcctt catcatcggg
    78721 gttgtcggag ctaaatttga aaaagctgtc cgcaaggttg ttccagatgt cattgacctc
    78781 ttggtaacac cattcgtgac acttttggtc atgtctatcc ttggactctt tgtcattgga
    78841 ccagttttcc acgttgttga aaactacatc cttattgcta caaaagcgat tcttagcatg
    78901 ccatttggtc ttggtggttt cttgattggt ggggttcacc aattgatcgt cgtgtcaggt
    78961 gtgcaccaca tcttcaactt gcttgaagtg caattacttg ctgctgacca tgctaaccca
    79021 ttcaacgcta tcatcacagc tgctatgaca gctcaaggtg ctgctactgt tgcggttggt
    79081 gttaaaacaa aaaatccaaa actgaaaaca cttgctttcc cggctgctct ttctgccttc
    79141 ctaggtatta cagagcctgc tatcttcggg gtgaacttgc gcttccgtaa accattcttc
    79201 ctttcattga ttgctggtgc aatcggtggt ggattggctt ctatccttgg acttgctggt
    79261 actggtaatg gtatcaccat catccctggt acaatgcttt atgttggtaa cggacaactt
    79321 ccacaatacc ttcttatggt agctgtatca tttgcccttg gttttgctct tacttacatg
    79381 tttggttacg aagatgaagt agacgcaact gcagctgcaa aacaagctga agtggctgaa
    79441 gaaaaagaag aagttgcgcc agcagctctt caaaatgaaa cacttgtaac tcctatcgtc
    79501 ggtgatgttg tcgctcttgc tgatgtcaat gacccagtct tctcaagtgg agctatggga
    79561 ccaggtatcg ctgtgaaacc aagccaaggc gtggtctatg caccagctga tgctgaagtt
    79621 tcaattgcct ttccaacagg gcacgctttt ggtttgaaaa caagaaatgg tgctgaagtt
    79681 ttgattcacg ttggtattga cactgtatct atgaacggtg acggttttga agcaaaagtt
    79741 gctcaaggta ataaggtgaa agctggcgat gttcttggaa catttgactc aaacaaaatc
    79801 gctgcagctg gacttgatga tacaacaatg gttatcgtta caaatacagc tgactacgct
    79861 tcagtagctc cagtcgcaac aggttcagtt gcgaaggggg atgctgtgat cgaagtgaaa
    79921 atctaatcaa tcctctctaa tgtgaaaacg aacaaatgac atgtttgttc gtttttatta
    79981 gatagtaaga tttacagagg aaaatctaaa aaatagagac atttagactt tcgaagtatg
    80041 ctataataaa gaaaataaaa acaagaggtt tatcatgaca aaattatatg gaagcttgga
    80101 agcgggcggt acaaagtttg tctgtgctgt cggtgatgaa aactttaacg ttgtagaaaa
    80161 aacacaattt ccaacaacaa ctccaatcga aacaatcgat aaaaccattg agttcttctc
    80221 aaaattcgat aaccttgctg gtcttgcagt tggttcattt gggccgattg atattgacaa
    80281 aaactcaaaa acttatggct ttatcacgac gactccaaaa ccaaactggg caaatgtgga
    80341 cttgcttggt gcccttcgtc gcgccctaaa cgtgccaatg tacttcacaa cagacgtaaa
    80401 cagctctgct tacggtgaaa tggttgcccg taacaatgct ggtggtcgta tcgaaaactt
    80461 ggtttactac acaatcggta caggtatcgg tgcaggcgtc atccaacgtg gtgagtttat
    80521 cggtggtgtg ggtcaccctg aaatgggtca ttattatgtt gctagacacc caatggatat
    80581 tgaaaaagag tttaagggtg tttgtccttt ccataaggga tgtctagagg gttatgcagc
    80641 tggtccaagt ttggaagctc gtacaggtgt acgtggggaa actattgaac tcaacaaccc
    80701 tgtttgggat gttcaagcct actatatcgc tcaagctgcg gttaatgcga cagtgacttt
    80761 ccgcccagac gtgattgtct ttggtggagg ggtcatggct caacaacata tgctggaccg
    80821 tgtccgtgag aaatttacat ctcttcttaa tggttaccta ccagtaccag atgtgcgtga
    80881 ctatatcgtg acgccagcag tcgcaggaaa tggttctgcc acacttggga actttgttct
    80941 tgcaaaagaa gtttcaaaat aaagcacaaa atccgcttgg gaaaccaaac ggatttttta
    81001 cgtgtcaaag catttgccag aaaaagtcaa taatataggt caaaccgtag gtataaacca
    81061 cgagggtaaa gggtttggtc agaatgatga tggtcatgta gcgcttgaaa ctcatcttgg
    81121 tcagggcagc cagcatacag agaaagtcag ctgggctaat gggccaaatc atcataaaaa
    81181 taaagaagcg gtcaaaacga ttgcccttat ctagccagcc gatgtacttg tcgtaggtgc
    81241 gcttgctgac gacagactgg acaaaggcag ctccgtatag gcgcactaga taaaagataa
    81301 tggcacagtc aatcacgatg ccgatatagt tgtagatagt cccgatgatg tgcccgtaga
    81361 taaagacccc agccaccgag gtcaaggccc ctggaatgat agggacgaca gtctgtaaaa
    81421 tctgtaaaaa gataaagaga ggtggacccc agatgcctgc ctgctggata aaggcagaga
    81481 gggtttcctt ggattgtaaa atcccagcct gataagccca aatacagaaa atcaaactcc
    81541 caaccccacc gacaatcgat gagatattga taactcgctg cagaagggga gaaacagctt
    81601 tcatttgttt atcctgtgac atgtaaactc ctcatagata gtatatttct actataccat
    81661 attttggagg agaaaggggg aatgagtctt ttttgataag gaatagaaag taaatagccc
    81721 ttcgagactt agaataggtc tgtcaactaa aggttatatg cattctaggt ttcgaataat
    81781 cgcaattcca tgaatttaaa agcattctaa gtttcgaata gcttatctga gataattttg
    81841 aggcattcgc gctttcgaat agtcattttc cctaaagttt agatgtattc tgaagctaga
    81901 aagactaaaa tctaaaagta gtaagagtct ctctctgatg gacgtaattt atggctagta
    81961 tgaatccttt gaattgttag ttaattttaa tattaatcag ttctgaaata attactaaat
    82021 atagttagat ggtgaattaa ttattgctaa atttcaagtt caagttagtc atccagaagt
    82081 cttctctggg ggacttgtag ttcaagcatt ttttaggata gttgttaatc cacttttcga
    82141 tgaatgcgac ttcctttgta gtcgttttct tagttccctg aggtaaccat ctatgaatga
    82201 acttgttgtg atttttatta gatcctatag tggtgtgcat aatagatata atagattgaa
    82261 actagaatag tacgcatcta cttctaaaac attgttagaa atcgatttga ctgtcccgat
    82321 ctatttgtcc tgtttttatt tcattttgct atataatcct tagaaaacat atcggacaag
    82381 cggttgaatt ccgttccgtc cattagtaga taaaggatta ctccttcttg aaatgacaga
    82441 tgaacttgtt tcttataaaa atgttgtctg aaactattcg cttttttcca gaagttttag
    82501 aggaagaaaa ctttatgagg aaaaaggagt tactcaaata acaattcagg attaaaaata
    82561 gacagttgag gagcggaagg tataaattaa gtttgctact gtataatgga tttatcacta
    82621 atactcttcg aaaatctctt caaaccacgt cagcttcgcc ttgccgtaga tatagttact
    82681 gacttcgtca gttctatcca caacctcaaa acagtgtttt gagctgactt cgtcagtttt
    82741 atctgcaacc tcaaagctgt actttgagca gcctacggct agcttcctag tttgctcttt
    82801 gcttttcatt gagtataaaa gtgctccagg ccatatttta cacagcaata gtcttctaaa
    82861 aatggacaaa aacattgtaa aggctatcaa aaaggagtat aatgagtgca agaaatttcg
    82921 gaggtgaaag atgctagaag taagaagtct agagaaaagt tttggctcca agcaagtttt
    82981 gtttggtatt gactttcaag cgcgaccagg tcgtattttg ggactagtcg gaaaaaatgg
    83041 tgctggaaaa acaacgattt tccatagtat tttgaaattc ctagaatatc agggagaaat
    83101 cggtctggat ggtcaggata ttcgtcagga gacctatgct cggattggtt atctgcctga
    83161 agaacgcagt ctcatgccta aattgacagt tcttgaacaa gttcgctact tggcgactct
    83221 aaaaggcatg gatgccaaag aagtcaaaga aaaactccct caatggatga agaggttgga
    83281 agtgaaagga aagctgacag ataaaatcaa gagtctgtca aaaggaaatc agcagaagat
    83341 tcagctcatt attactctga ttcatgaacc agacctgatt atcttggatg agccttttag
    83401 tggattggac ccagttaata cagaattgct caaacaagtc atttttcagg aaaaagagcg
    83461 cggagcaacc attatctttt ctgaccatgt catgaccaat gttgaggaac tttgtgacga
    83521 tattctgatg atccgagatg gccgtgtggt cttgcacgga ccagttcagg atgtccgcaa
    83581 tcaatacggg aaaacgcgtc tctttgtttc aagtgaacga agcaaggaag aattggaaaa
    83641 tcttcctcat gtcaaacagg tgagcttgac caaacaaggc agttggaaat tgattttgga
    83701 ggatgagagc gctggaaggg aactcttccc aatcttgact caaggtcaat atatcgcaac
    83761 atttgaccaa caagcgccaa ctatcgatga aatctttaaa ctagaatcag gagtggaagt
    83821 atgagaaata tgtgggttgt aatcaaggaa acctatcttc gacatgtcga gtcatggagt
    83881 ttcttcttta tggtgatttc gccgttcctc tttttaggaa tctctgtagg aattgggcat
    83941 ctccaaggtt cttctatggc taaaaataat aaagtggcag tagtgacaac agtgccatct
    84001 gtagcagaag gactgaagaa tgtaaatggt gttaacttcg actataaaga tgaagcaagt
    84061 gccaaagaag caattaaaga agaaaaatta aaaggttatt tgaccattga tcaagaagat
    84121 agtgttctaa aggcagttta tcatggcgaa acatcgcttg aaaatggaat taaatttgag
    84181 gttacaggta cactcaatga actgcaaaat cagcttaatc gttcaactgc ttccttgtct
    84241 caagagcagg aaaaacgctt agcgcagaca attcaattca cagaaaagat tgatgaagcc
    84301 aaggaaaata aaaagtttat tcaaacaatt gcagcaggtg ccttaggatt ctttctttat
    84361 atgattctga ttacctatgc gggtgtaaca gctcaggaag ttgccagtga aaaaggcacc
    84421 aaaattatgg aagtcgtctt ttctagcata agggcaagtc actatttcta tgcgcggatg
    84481 atggctctgt ttctagtgat tttaacgcat attgggatct atgttgtagg tggtctggct
    84541 gccgttttgc tctttaaaga tttgccattc ttggctcagt ctggtatttt ggatcacttg
    84601 ggagatgcta tctcactgaa taccctgctc tttattttga tcagtctttt catgtacgta
    84661 gtcttggcag ccttcctagg atctatggtt tctcgtcctg aggactcagg gaaagccttg
    84721 tcgcctttga tgattttgat tatgggtggt ttttttggag tgacagctct aggtgcagct
    84781 ggtgacaatc tcctcttgaa gattggttct tatattccct ttatttcgac cttctttatg
    84841 ccgtttcgaa cgattaatgg ctatgcggag ggagcggaag catggatttc acttgctatt
    84901 acagtgattt ttgcggtggt agcaacagga tttatcggac gcatgtatgc tagtctcgtt
    84961 cttcaaacgg atgatttagg gatttggaaa acctttaaac gtgccttatc ttataaatag
    85021 aagagccttg cgaaagcgag gtttttaaag gtgaaaaggg tggaatcacg aacctaatta
    85081 tgtacacatt atgtaaacag gttgcttgaa aactcaattg tatagtgaac tgaatctgga
    85141 ataggataat attacttcta aaacattctt ataaattgat ttgaattcca aaatcccatc
    85201 gttccgttct tatttcattt tgcgatatag cgaaaggaaa taagtcagct cacaaaaaac
    85261 gcataatatc aaggattttt aacacttgat actatgcgtt ttctaatttt aaagactttt
    85321 tgcctggtct cttttgttct atgagtatgt tacatatcta ggtaaaaatt atttaaagca
    85381 aattaacctt atttctcaag atgtagtagg ttccgagata aaagatagct atgaatatga
    85441 gttctttaac aatggctata cctgctccca tatagaaatg gtcattgagt cctaccagtg
    85501 aattgacata gaaattggaa ctaagattga agaaaagttc aataaatcca atgacgattt
    85561 ggataccaat gtaggctgca acagcgagtg ctgtacggta ttcattgaaa agctgtccaa
    85621 tggaaatagc caggtagatg cagaggattc ctgaaatggt atttagtagg aaggatatac
    85681 ctgtaagaaa gatctgaggg agatgtgttt ctacaaatgt aatcacataa gaaagaggaa
    85741 tccattctgg agctgttaaa gccagaataa taacagcact tagagccaat acagcggtgc
    85801 taatcaatga ccagataaag gcaccgatta gtttggctgt gatgatatgg tgttcagaaa
    85861 ctggcaaggt caaagtcaga tagccttgtc ggtcgtagac actacctttg aagcgtttaa
    85921 taatcaagaa aatggttgaa atcgcaagtg taagcatcaa gccaccaaag actgtagcta
    85981 gaaaaagtag catagtagcc tgactttctt ggtaaggtag atttttaaag ccttgtgtct
    86041 gtattccgat gagggcagaa aggactagca cggctgcgta gagggctaaa taccacttgt
    86101 taacattttt aaattcgtag tgaactaaat tccaaaacat aaataatctc ctttgcttag
    86161 gccttaaatt cctgacggaa gagttggtca atggattcac ctgactcgta gcgaatatca
    86221 tctacatttc cttgacggac gacttttccg tcttttagga agacaatttc atccaagatt
    86281 ggctcgatat cagaaatcaa gtgggtagaa atcaaaacgg tagaagttgg tgagtagttg
    86341 ttgataatgg tattgaggat ataagcacgg gctgctggat ccaccccacc aatgggttca
    86401 tccaaaacat agagacgagc atcacggctc ataaccaaaa tcagttgaac cttttctttg
    86461 tttccttttg atagtttctt gagacgacta ttttcatcaa tgcccaggtc tgcaagtaga
    86521 tgatgagcgc gttcaagatt gaaatcttta tagaaggtct tgaagtaggt tagggcttct
    86581 ttgaccttca tttgctcatt gagataggtc gtatcaggca aataagctac aacggccttg
    86641 gttgctgggc ttgggtccat gtcgttgatg aggacacgtc cttgatctgg ttgtaagagg
    86701 ccattaatta gtttaatcag ggttgttttt cctgagccgt ttggcccaag aaggccgaca
    86761 atttttccag ctggaatgtc aagagaaaca ttttcaaggg ctggtgttgc tccatatgat
    86821 ttggatacat tttcaaatgc tagtaatgac ataggcttaa actcctttaa tataatcact
    86881 gactacgcct ggtagttctt ctttttcata gccaaaatgg gtcatggagg aaacgaagtg
    86941 ttccaattct tcttctgata attgtttgcg tgactgagcg attagctcct tatccttagt
    87001 cacaaatcgt ccagttgttc gcttgctgta gacaaatcct tctcgttcaa ggtctgataa
    87061 ggctctttgg atggtattgg gattgacacc agcctcgcta gctagctccc tcacggttgg
    87121 aagttgttga ttgggttcca gtgtatggga aacaatctga agcttgattt tctccataat
    87181 ctgtaaatag atgggttttt tgttgtcaaa tgtccaggac atcttagtct cctttctctt
    87241 atccttttgt cttaattaaa taatacaaca aaacaaaaaa cttgtcaagc aaaaagaaga
    87301 attgttttgg gaatcgctta aaaaatggta taatgaaaag aaaacgataa ggagggaaag
    87361 gatgcgttgt ccaaaatgtg gggctaccaa gtcaagtgtt atcgatagtc gccaagcaga
    87421 agaagggaac accattcgta gaagacgaga gtgcgacgag tgccaacacc gttttacaac
    87481 ctacgaacga gtagaagaaa gaaccttagt ggttgttaaa aaagatggca cacgggaaca
    87541 attctccaga gataaaatct ttaatgggat tatccgctca gcccagaaac gtcctgtgtc
    87601 aagtgatgaa atcaacatgg tagtcaatcg tatcgaacag aaactccgtg gtcgaaatga
    87661 aaatgaaatt caaagtgagg acattggttc acttgtcatg gaggagttgg ctgaattgga
    87721 cgagattacc tatgtacgtt ttgctagtgt ctatcgtagt tttaaggatg tcagtgagtt
    87781 agagagcttg ctccaacaaa tcacccagtc ctctaaaaag aaaaaggaaa gataaatgaa
    87841 gccaattgac cgtttttctt atctaaagaa taatcgggtg tcgcaagata cctcatctct
    87901 ggtacagtgc tacctcccga ttatcggtca ggaggcactg agcctttatc tttatacaat
    87961 cagtttttgg gataatggta gaaaggaata tcttttttca agtatcctca atcatctcaa
    88021 ctttgggatg gatagactga taaaatcatt gaaaatctta tctgctttta atctcttgac
    88081 cctctatcaa aagggggatg tttatcagct agccctccat gctcctctat ctagtcaaga
    88141 cttcttggag catcctgttt atcgcagact cttagagaaa aagattggcg actctgctgt
    88201 ggaggatttg aaagttgaaa gtgctgatgg tgaagaaata cctgtctcac tcaatcaagt
    88261 ctttccagaa ttggcagaac taggcagtca agaagacctt ggtctcaaga agaaagtggc
    88321 caatgatttt gacttggaac attttcgcca gctgatggct cgagatggac ttcgttttgc
    88381 ggatgagcag tccgatgtct taaacctctt tgctattgcc gaggagaaga aatggacttg
    88441 gtttgaaacc tatcaattgg ccaagtcaac agctgtttct caggttattt caaccaaacg
    88501 catgcgtgaa aaaattgctc aaaaaccagt ttcctctgac tttagtctta aggaaacaac
    88561 cattatcaaa gaagccaaaa gtaaaactgc cctgcagttc ttggcagaaa tcaagcaaac
    88621 acgcaaggga accattaccc aaacagaaag agaactcttg caacagatgg ctggcttggg
    88681 cttgctggac gaagtcatca atatcattct tttattgacc tttaataagg tcgattcggc
    88741 aaatatcaat gagaaatatg ccatgaaggt agccaatgac tatgcctatc aaaagattca
    88801 ttcggcagaa aaggcagtct tgcgcatccg tgagcgaggg cagaaaacaa aaacacaaaa
    88861 acagaatcag actgccccag caaaaaccaa tattcctaaa tggagtaatc ctgaatataa
    88921 aaatacgtca tccgctgagg aattagaaga gatggaacgc caaaccctag aattattagc
    88981 aaaattagat aacggaggtg attagatgga aagtgtcgga gatgtactca aacgtcaacc
    89041 aagtcgtttt cactatcaag atttagttca gaaaatcatg aaggatcctg atgttgcggc
    89101 ctttgtccag caagaatccc tcaatcagga cgagttgaac cgtagtattt ccaagtttaa
    89161 ccaatacatc actgagagag ataaattcct ccgaggagat acagattata ttgccaaagg
    89221 ctacaagcct atattagtca tgaaccatgg ctatgcggat gtttcttatg aagaaactcc
    89281 tgaactaatc gcagctgaaa aagaagcggc tatcaagaaa cgtctcaact taattaattt
    89341 tccatctagc ctgaaaaatg tcagtttttt agatgtttat cgtgatgatg ttcagcgctt
    89401 aactgttcta aaaagaatga tagaatttgt taacgattac cccaataatt tgaaaggtct
    89461 ttacttatat ggagactttg gtgtgggtaa aagtttcatg gtggctgccc tagctcatga
    89521 tttatcagaa aaacgtggtg tatcatccac tctcctccac tatcctagct ttgtcattga
    89581 tgtcaaaaat gctatcggtg atggcaatgt taagacctta gtggatgaga ttaagctttc
    89641 tgaagtcctg attttagatg atattggtgc cgagcaatcc accgcttggg tgcgtgatga
    89701 aatcctgcag gtcattctcc aatatcggat gcaggaaaat ttaccgacct ttttcacctc
    89761 taacttcaac tttgaagatt tggagaagca tttcgctaaa gggaaaaatg gaaatgacga
    89821 aacctgggaa gccagacgtg tcatggaacg catccgttat ttggctgagg agactcgttt
    89881 agaaggagta aaccgtcgat gacagaaacc attaaattga tgaaggctca tacttcagtg
    89941 cgcaggttta aagagcaaga aattccccaa gtagacttaa atgagatttt gacagcagcc
    90001 cagatggcat catcttggaa gaatttccaa tcctactctg tgattgtggt acgaagtcaa
    90061 gagaagaaag atgccttgta tgaattggta cctcaagaag ccattcgcca gtctgctgtt
    90121 ttccttctct ttgtcggaga tttgaaccga gcagaaaagg gagcccgact tcataccgac
    90181 accttccaac cccaaggtgt ggaaggtctc ttgattagtt cggtcgatgc agctcttgct
    90241 ggacaaaacg ccttgttggc agctgaaagc ttgggctatg gtggtgtgat tatcggtttg
    90301 gttcgataca agtctgaaga agtggcagag ctctttaacc tacctgacta cacctattct
    90361 gtctttggga tggcactggg tgtgccaaat caacatcatg atatgaaacc gagactgcca
    90421 ctagagaatg ttgtctttga ggaagaatac caagaacagt caactgaggc aatccaagct
    90481 tatgaccgtg ttcaggctga ctatgctgga gcgcgtgcga ccacaagctg gagtcagcgt
    90541 ctagcagaac aagcgtctag cagaacagtt tggccaagca gaaccaagct caactagaaa
    90601 aaatcttaaa cagaagaagt tattgtagaa agtgagaaat tatggcccta ccaactattg
    90661 ccattgtagg acgtcccaat gttgggaaat caaccctatt taatcggatc gctggtgagc
    90721 gaatctccat tgtagaagat gtcgaaggag tgacacgtga ccgtatctat gcaacgggtg
    90781 agtggctcaa tcgctctttt agtatgattg atacaggagg aattgatgat gtcgatgctc
    90841 ctttcatgga acaaatcaag caccaggcag aaattgccat ggaagaagca gatgttatcg
    90901 tttttgtcgt gtctggtaag gaaggaatta ctgatgcaga cgaatacgta gctcgtaagc
    90961 tttataagac ccacaaacca gttatcctcg cagtcaacaa ggtggacaac cctgagatga
    91021 gaaatgatat ctatgatttc tatgctctcg gtttgggtga accactgcct atctcatctg
    91081 tccatggaat cggtacaggg gatgtactag atgcgattgt ggaaaacctt ccaaatgaat
    91141 atgaagaaga aaatccagat gtcattaagt ttagcttgat tggtcgtcct aacgttggaa
    91201 aatcaagctt gattaatgct atcttgggag aagaccgtgt cattgccagt cctgttgctg
    91261 gaacaactcg tgatgccatt gatacccact ttacagatac agatggtcaa gagtttacca
    91321 tgattgatac ggctggtatg cgtaagtctg gtaaggttta tgaaaatact gagaagtact
    91381 ctgtcatgcg tgccatgcgt gctattgacc gttcagatgt ggtcttaatg gtcatcaatg
    91441 cggaagaggg gattcgtgaa tacgacaagc gtatcgctgg atttgctcat gaagctggta
    91501 aagggatgat tatcgtggtc aacaagtggg atacgcttga aaaagataac cacactatga
    91561 aaaactggga agaagatatc cgtgagcagt tccaatacct gccttacgca ccgattatct
    91621 ttgtatcagc tttaaccaag caacgtctcc acaaacttcc tgggatgatt aagcaaatca
    91681 gcgaaagtca aaatacacgt attccatcag ctgtcttgaa cgatgtcatc atggatgcca
    91741 ttgccatcaa cccaacaccg acagacaaag gaaaacgtct caagattttc tatgcgaccc
    91801 aagtggcaac caaaccacca acctttgtta tctttgtcaa cgaagaagaa ctcatgcact
    91861 tttcttacct acgtttcttg gaaaatcaaa tccgcaaggc ctttgtcttt gagggaacac
    91921 cgattcatct catcgcaaga aagcgtaaat aaaaaagtag aatctggaat gacatttcca
    91981 gattcttttg atataataaa ataatagaaa acgctatcaa aagaaggagg gggatgtcgg
    92041 tgatggaaca tttgtttaaa ttcttacttt tagcaccgta cttttatttt gataactgga
    92101 ttgaaaaggc caacagaaat agtaagtttt ttccaatttt ttattatttt tactggattt
    92161 acatcccctt ctattctctt tttagccttg cttggacagt tgtttcagtt ctgtttttca
    92221 ataccgtctt gagaaatgtg acagatatca agttatgggg catttggttt ctttttattc
    92281 tgctagctat tggtatgaat tggttaactt attcctgttt caaagaaatg tttcgcttga
    92341 gacaggaact agggaagtct aagggtggaa ggcattgatt tatatcggtt tctatttgta
    92401 ggaggtggct tatggtacct ctaaaatcat ttattacacg ctattccaag gtttatattg
    92461 gtaataacat ttaatagaac gaaactaaag aaaacaattt aaaaaaggag gcttgtgatg
    92521 gaacacttgt ttaaaatgat aatcttatta ccctgttttt actttttcag ctggattgac
    92581 aaggataata gagaaagtaa atttttccca attttttact atttttactg gatttacatc
    92641 cccctctatg ctctttttag cctttcttgg acagtttttt cagttctgtt tttcaatatc
    92701 gtcttgagaa atttgacaga tatcaagtta tggggtattt ggctattatt actacttatc
    92761 gcttttgcta gtgactggtt agactatatc tgtttcaaaa aaatgcttga cttgagacgg
    92821 gaactaggga agtctaaagg cggaaggcat tgatttatac tcttcgaaaa tctcttcaaa
    92881 ccacgtcaac gtcgccttgg attatatatg taactgactt cgtcagtctt atctacaacc
    92941 tcaaagcagt gctttgagca acttgcggct agtttcctag tttgctcttt gattttcatt
    93001 gagtattata ttactttcta tttgtaggag gtggcttatg aagattcctc tcttaacttt
    93061 ggcaaggcat aaatttgttt atgtcttgct tactttgctt tttcttgctt tggtttatcg
    93121 tgatgttttg atgacttatt tcttttttga tattcatgcg cccgatctag ctaaattcga
    93181 tggacaagca attaaaaatg acttattaaa atcagcatta gattttcgta ttctccagtt
    93241 caatctaggt ttttatcaat catttattat tccaatcatc attgttttgc taggttttca
    93301 atatattgag ctgaaaaata aagttttacg attgagtatt ggaagagaag tgagttatca
    93361 agggttaaaa agaaagttga ctttgcaagt tgcaagtatc ccttgtttga tatatttagt
    93421 gactgtgctg ataattgcaa ttgtaaccta tttctttggg actttttctc ctcttggatg
    93481 gaattctcta ttttctgatg gaagtggttt acaaagactc ctagatggag agataaaaag
    93541 ctatttgttc tttacttgtg tcctactaat cggtattttc atcaatgcaa tctatttttt
    93601 acaaatagtt gattatgtgg ggaatgtgac tcgttcggca atcacctatt tgatgtttct
    93661 ttggcttggt tctatgctgc tctatagtgc cttgccttac tatatggttc ctatgacgag
    93721 tttgatgcaa gctagctatg gggatgtaag tttgatgaaa ctctttactc cttatatcct
    93781 ttatgttgtc ccttatatgg tgcttgaaaa atatgaagat aatgtttaag aattttaaca
    93841 atatttggct aaagagaaag attgttttac tacttcgtat agttctgatg atgattttga
    93901 taaaccatct attgtcaaca gcggttcaaa agcaggatgc tgttatcttt ttcaagagag
    93961 aattgatttc aattttttcc tataatgact attctgaagc gaatttagaa atccccaaac
    94021 tcttgttaaa cctttcgctt ttcatggtag gatggctctc tgtcatttta cttgaaagtg
    94081 atttggcaga ccattaccat cacttgattc gctatcaatc aagctccttt ttcgattata
    94141 caaggaaacg attggttgtc atttctaaat tttttactca agatttgttt gtctggtttc
    94201 ttggtttact tccgctagga attcatttca aaacagtcgc acttttcttt ttacttgctc
    94261 agttaatgat tttgtactta ctactgtctt atctgatagc actgattagt gcgggcgctg
    94321 gtttttcctt ttttctctat tttttagcat ttgtgggaca agaatggatg atggatcata
    94381 ttgtaacagt gtatttacta ctcttaagct tattagttat gttgattgtt agtcgcttgg
    94441 aagagaaatt taagaaagta taaacgatga gacttgaaat tataaatgga cagaaaattt
    94501 atgggaaaag acctatttta aatcagttga atttggtgtt tcaatcagga aaaatttatg
    94561 gacttaaagg tgataatgga tctggcaaga cggttctttt aaagatactt gctggttata
    94621 ttaagtttga caaaggaaaa gttcttcaag acgggaaagt ttacgggata aaaaatcatt
    94681 atattcagga tgcaggaatt ttaattgaaa aagtcgagtt tttatctcat ttatccctga
    94741 gagaaaattt ggaactgtta aggtattttt catctaaagt tacggaaaaa agaattgcct
    94801 attggattca atactatgat ttacaggaat ttgaagacgt tgaataccgt catttatcct
    94861 tgggaacaaa gcaaaaaatg gccttgattc aagcctttat ttcctctcct tctatactct
    94921 ttctcgatga acctatgaat gctttggatg agaagagtgt gaggttaacc aaacaggtca
    94981 ttttatctta cctgaaaaaa gaaaatggtc tggttatcct gacgtcgcac atatcggaag
    95041 atatttcaga cctttgtaca gatgtattag ttgtcgaaaa tggacatata caaatgtaaa
    95101 ggatatacaa tcctaggaga tggcttatgg cacatctaaa atcatttatt acacgctatt
    95161 ccaaggttta tattggttta gttctgctga tctggctgtc tttcttcttt atcccttggg
    95221 atagagcgat tctgggggta aggattgaca tcttcatcat acagaaagtc ttgctagttt
    95281 ttggaattct gtccattttg atggccttgc tgtccaagaa agtcagtctc tttgtttttg
    95341 gactgatttg ctgtctttct ctttggatta acttatttat cacatttgcc attttgccaa
    95401 tttttggcaa ttaaacagtc ataaaagtcg gagaggttag cttgaaaact aacctctttt
    95461 tccttttcaa aatggggatt cttccttgaa aataatcagt aattgtgcta aaattaaagg
    95521 aacattctaa aatattcgga atttaaagta aggaaaaaca tggctaatat tttaaaaaca
    95581 attatcgaaa atgataaagg agaaatccgt cgtctggaaa agatggctga caaggttttc
    95641 aaatacgaag accaaatggc tgctttgact gatgaccaac taaaagcaaa aacagttgaa
    95701 tttaaggaac gttatcaaaa tggagaatca ctggattcat tgctttacga agcatttgcg
    95761 gttgtccgtg aaggtgccaa acgtgtccta ggtctcttcc cttataaggt tcaggtcatg
    95821 ggggggattg ttcttcacca tggtgacgtg ccagagatgc gtacagggga agggaaaacc
    95881 ttgactgcga ccatgccggt atacctcaat gccctttcag gtaaaggggt tcacgtagtt
    95941 acggttaatg aatacctgtc agaacgtgac gcgactgaga tgggtgaatt gtactcttgg
    96001 cttggtttgt cagtagggat taacttggct accaaatctc caatggagaa aaaagaagcc
    96061 tatgagtgtg atattactta ctcaactaac tcagaaatcg gatttgacta ccttcgtgac
    96121 aacatggtcg ttcgcgctga aaacatggta caacgtccgc ttaactatgc cttggtcgat
    96181 gaggttgact ctatcttgat tgacgaggct cgtacacctt tgattgtatc aggtgccaat
    96241 gcggttgaaa ccagtcagtt gtatcacatg gcagaccact atgtaaaatc tttgaacaaa
    96301 gatgactaca tcatcgatgt gcagtctaag actattggtt tgtctgattc agggattgac
    96361 agggctgaaa gctacttcaa acttgaaaac ctctatgaca tcgaaaacgt ggctttgacc
    96421 cactttatcg ataacgccct tcgtgccaac tacatcatgc ttctcgatat tgactatgtg
    96481 gtgagcgaag agcaagaaat cttgattgtc gaccaattta caggtcgtac catggaaggt
    96541 cgtcgttatt ctgatggatt gcaccaagct attgaagcca aagaaggtgt gccaatccag
    96601 gatgaaacca agacatctgc ctcaatcacg taccaaaacc ttttccgtat gtacaaaaaa
    96661 ttgtctggta tgacgggtac aggtaagact gaggaagaag aatttcgtga aatctacaac
    96721 attcgtgtta ttccaatccc aacaaaccgt cctgttcaac gtattgacca ctcagacctt
    96781 ctttatgcaa gtatcgaatc taagtttaaa gcggttgtcg aagacgttaa ggctcgttac
    96841 caaaagggtc aacctgtctt ggttggtaca gtagcggttg aaactagtga ctacatttct
    96901 aagaaattgg tcgcagctgg tgttcctcac gaagtcttga atgccaaaaa ccactataga
    96961 gaagcccaaa tcatcatgaa tgctggtcaa cgtggtgccg ttaccatcgc aaccaacatg
    97021 gcgggtcgtg gtaccgacat caagcttggt gaaggtgttc gtgaacttgg aggactttgt
    97081 gttattggta cagaacgtca tgaaagtcgt cgtatcgata accagcttcg tggacgttca
    97141 ggtcgtcaag gagatccagg tgagtcacaa ttctacctat ctcttgaaga tgatttgatg
    97201 aaacgttttg gttctgaacg cttgaaggga atctttgaac gcttgaacat gtctgaagag
    97261 gcgattgagt ctcgcatgtt gacgcgtcag gttgaagcag ctcagaaacg tgtcgaagga
    97321 aataactacg atacccgtaa acaagtcctt caatacgatg atgtcatgcg tgaacaacgt
    97381 gagattatct atgctcaacg ttacgatatc atcactgcag atcgtgactt ggcacctgaa
    97441 attcagtcta tgattaagcg cacgattgaa cgtgtcgttg atggtcatgc gcgtgccaaa
    97501 caagatgaaa aactagaggc aattttgaac tttgctaagt acaacttgct tcctgaagat
    97561 tctattacga tggaagactt gtcaggcttg tctgataagg ccatcaagga agagcttttc
    97621 caacgtgcct tgaaggttta cgatagtcag gtttcaaaac tacgcgatga agaagcagtt
    97681 aaagaattcc aaaaagtttt gattctacga gtggtggata acaagtggac agatcatatc
    97741 gatgcccttg atcaattgcg taacgcggtt ggacttcgtg gctatgctca gaacaaccct
    97801 gttgttgagt atcaggcaga aggtttccgt atgtttaatg atatgattgg ttcgattgag
    97861 tttgatgtga cacgcttgat gatgaaagca caaattcatg aacaagaaag accacaggca
    97921 gaacgtcata tcagtacaac agcgactcgc aatatcgctg ctcaccaagc aagtatgcca
    97981 gaagatttgg atttgagcca gattggacgc aatgaacttt gcccatgtgg ttctggtaag
    98041 aaatttaaaa actgtcacgg taaaagacaa taaaatgaga tagtttagag gcggatatct
    98101 tgtgaaaagt aaatttttac tgggtatccg tttgctttat aaggagatga gttatggtat
    98161 ttacagcaaa aagctctaaa ataaatatag aagaagttcg tgccttgtca aaattagaag
    98221 gtcaggcttt ggagaggaaa tcacagcgag atcaagagct agaagccatt atacgtggag
    98281 aagaccagcg aattctcttg gtaatcgggc catgctcatc tgacaacgaa gaagctgtcc
    98341 ttgaatacgc taagcgtttg gcagtcctac aagaagaagt ggcagatcgt atctttatgg
    98401 ttatgcgtgt ttatactgcc aaaccccgta ccaacggaga tggctataag ggcttgattc
    98461 accagcctaa cgcgacagaa gcgcctagtc ttatcaatgg aatcaaagcc gttcgccatc
    98521 ttcactatcg tgtcatcaca gaaacaggga tgacaactgc tgatgaaatg ctttatcctg
    98581 aaaaccttcc gcttgtagat gatttgattt cttacatggc agttggtgcc cgttcagttg
    98641 aagaccagca acaccgcttt gtggcaagtg gggcaggatt ttctactggt tttaaaaatc
    98701 caacctctgg aaatctcaat gtcatgttta atgggattta tgctgctcaa aacaaacaaa
    98761 gtttcctttt cttaggaaaa gaagtagaaa caactgggaa cccgctttca cacgctattc
    98821 ttcgtggtgc tcttaatgag tatggaaaaa atattcccaa ctactattat gacaatttaa
    98881 ttgataccat tgcccagtat gagaaaatgg gcttggaaaa tccttttatc atcattgata
    98941 ccaatcatga caattctggt aagcagtata ttgaacagat ccgaattgtc cgccagacct
    99001 tgattaaccg tgcttggaat gaaaaaatta agcagttcgt tcgtggtttt atgattgagt
    99061 cttatctgga agatggtcga caaaatgagc cagaagtatt tggtaagtct atcacagacc
    99121 cttgcctggg ttgggataac acagaagctc ttgtcagaga aatttacaaa acgttaggag
    99181 aataagatgg catttattga aaaaggtcaa gaaatcgata tggaagtcat caaggctgaa
    99241 acccaattgt ctgcggaagc cttgagactc aaggaaagcc gtgacaggga attggcagat
    99301 attatttcag gggaagatga ccgtattctc ttggtgattg gtccttgctc ttctgataat
    99361 gaagaggcgg tcttggaata tgctcgccgt ttatccgcct tgcaaaagaa ggtagcggat
    99421 aagattttca tggtcatgcg cgtgtatact gctaagcctc gtaccaatgg agacggctat
    99481 aaaggattag ttcaccagcc agatacttct aaggctccaa gcctgattaa tggcttgcag
    99541 gctgtgcgcc agttgcacta ccgcgtgatt acagagactg gtttgacaac ggcagatgag
    99601 atgctttatc cgtcaaatct gatcttggtg gatgacttgg tcagctacca tgccgttgga
    99661 gctcgttctg tggaagacca agagcaccgc tttgtggctt ctgggattga tgcaccagta
    99721 gggatgaaaa atccaacctc aggaaatttg ggtgttatgt ttaacgccat ctatgctgct
    99781 caaaacaagc aaaccttcct ttatcatggg caggaagttg agacatcagg taatcctttg
    99841 gcccatgtta tcctccgtgg agcagtcaac gagtatggca attatatgcc gaattactac
    99901 tatgaaaacc tactccaagc cattgaacgc tatgaaacca tgggacttga aaatcctttt
    99961 atcctcattg acaccaacca tgataactca ggcaagcaat atatggagca gattcgaatt
   100021 gttcgccaga ccttgcagaa tcgtgattgg aatgagaaaa ttaaaaagac ggttcgagga
   100081 tttatgattg aatcttacct agcagatggt cgtcaaaacc aaccagagat ctttggttgc
   100141 tctattactg acccttgcct aggttgggaa aatacagagg ccttggtaga agagatttat
   100201 gttaccttga caaaataagt gaaaaggatg gagttgggga atctcaactc cttttgatga
   100261 gaatgatagt tggacacgga attgacatcg aagaattggc ttcgatagaa agcgcagtta
   100321 cacgacatga aggatttgct aagcgtgtac tgaccgctca ggaaatggag cgcttcacca
   100381 gtctcaaagg acgcaggcaa atagaatatt tagctggtcg ctggtcggct aaggaggcct
   100441 tttccaaggc tatgggaacg ggcattagca agctcggttt tcaggatttg gaagtcttga
   100501 acaatgaacg tggggcgcct tattttagtc aggcaccatt ttcaggaaag atttggctgt
   100561 ctatcagcca caccgatcag tttgtgacag ccagtgtcat tttggaggaa aatcatgaaa
   100621 gctagtccac atagaccaac caaggctctg attcatctgg gagctattcg acaaaatatt
   100681 cagcaaatgg gggctcatat ccctcaagga acgctcaagt tggctgtggt taaggccaat
   100741 gcttatggtc atggagctgt tgccgttgcc aaggcaattc aagatgatgt tgatggcttt
   100801 tgcgtttcca atatcgatga agccattgaa ctcagacaag ctggactcag caagccaatc
   100861 ctcattttag gagtttctga aatcgaagct gttgctctag ctaaagaata tgacttcacc
   100921 ttgacagtgg ctggactgga gtggattcaa gcactcttag ataaggaagt ggacctaact
   100981 ggattgacag tccacctcaa gattgattca gggatgggac ggattggttt tagagaggcc
   101041 agtgaggttg agcaggctca agatttgctc caacaacacg gtgttcgtgt tgaaggaatc
   101101 tttacccact ttgctactgc tgatgaggaa tcagatgact attttaatgc ccagttagaa
   101161 cggtttaaaa ctattttagc tagtatgaag gaagttccag agctggttca tgctagcaat
   101221 tctgcaacga ctctttggca tgtagagact attttcaatg cggttcgtat gggagatgcc
   101281 atgtatggcc tcaatccaag tggagcggtc ttggatttgc cttatgattt gataccggcc
   101341 ttgaccttgg agtctgctct ggttcatgtc aagacagttc cagctggagc ttgcatgggc
   101401 tatggagcaa cttatcaagc ggatagcgag caagtcatcg cgaccgtgcc aatcgggtat
   101461 gcagatggat ggacaagaga catgcaaaat ttctctgtct tggtagatgg ccaagcttgc
   101521 ccaattgtcg gcagggtttc gatggaccaa atcactattc gattgcctaa gccttaccca
   101581 ctcggaacca aggtaacctt gattggctcc aatggggata aggaaatcac tgcaactcag
   101641 gtagcgacct accgcgtaac cattaactat gaggtggttt gcctcctcag cgaccgtatt
   101701 ccgagagaat attattagaa aagaaaggag tggagcatga atctacatca acccttgcat
   101761 gtcttgcctg gtgtgggacc aaagtcagca gaaaaatacg ccaaactagg aattgaaaac
   101821 ttgcaagatc tcttgctcta ctttcctttc cgttatgaag acttcaaaac caagcaggtg
   101881 ctggagctgg aagacggtga gaaggcagtt ctttctggtc aggtagtgac tcctgctagt
   101941 gtccagtatt atggtttcaa gcgcaatcgc ctgcgtttta gtctcaagca gggagaggtc
   102001 gtttttgcgg tgaatttctt taaccagccc tatctggctg ataaaataga gttgggagca
   102061 acccttgctg tctttggaaa atgggaccgc gctaaggcta gtctgactgg gatgaaggtt
   102121 ctggctcagg tagaagatga cctccagcct gtctatcgtc tggctcaggg aatcagtcag
   102181 gccagtctgg ttaaggtcat caagacggct tttgatcagg gactggacct cttgatagaa
   102241 gaaaatctgc cccagtcttt actagacaaa tacaaactca tgtcccgttg tcaggcagtc
   102301 cgagctatgc attttccaaa ggatttggca gaatacaagc aggctcttcg ccgtatcaag
   102361 tttgaggaac tcttttattt ccaaatgcag ttgcagacgc tcaagtctga aaatagagtt
   102421 cagggaagtg gtctggttct gaattggtct caggaaaaag tgacagcagt taaagtaagt
   102481 cttccttttg ccctgaccca agctcaggaa aagagtttgc aggaaatttt aactgatatg
   102541 aagtccgacc accacatgaa tcgtctccta caaggggatg tggggagtgg aaaaacggta
   102601 gtcgctggct tggccatgtt tgcggcagtg acagcaggtt atcaggctgc cctaatggta
   102661 ccaacagaaa tcctcgcaga gcaacacttt gagagtttac agaacctttt tcccaatttg
   102721 aaattggctc tcttgacagg ttccttgaaa gctgcagaaa agagagaagt cttgcagacc
   102781 attgccaagg gtgaggctga tttgattata ggaactcacg ctctgataca agatggggtg
   102841 gagtatgctc gtcttggttt gattattatc gatgagcagc accgttttgg tgtagggcaa
   102901 aggcgtattt tacgggaaaa aggtgacaat ccagatgtcc tcatgatgac ggcgactccc
   102961 attccacgga cgcttgccat cacagccttt ggagatatgg atgtttccat tatagaccag
   103021 atgccagcag gtcggaagtc tattgtgacg cgctggatca aacatgagca actacctcag
   103081 gtcttgactt ggttagaggg ggaaattcaa aaaggttccc aagcctatgt catctctcct
   103141 ttgattgaag aatcagaagc tctagatttg aaaaatgcca ttgccttatc agaggagttg
   103201 acgactcatt ttgcatgcaa ggcagaggtg gctcttctac atggtaggat gaagagtgac
   103261 gaaaaagacc agatcatgca ggatttcaag gagagaaaga cggatattct ggtttcgacg
   103321 acggttattg aggttggggt caacgttccc aatgcgactg tcatgattat catggatgcc
   103381 gatcgcttcg gtctcagtca acttcaccag cttagaggtc gtgtcggtcg gggggacaaa
   103441 cagtcctacg ctgttctcgt tgccaatccc aagacggatt ctgggaaaga ccgcatgcgc
   103501 atcatgacag aaacgaccaa tggatttgtc cttgcggagg aagatttgaa aatgcgtggt
   103561 tctggtgaga tttttggaac cagacagtca ggacttccag agttccaagt ggctgatatt
   103621 atcgaagatt ttccgatttt agaagaagca agaaaggttg ctagctacat tagttctata
   103681 gaagcttggc aagaagatcc agagtggcgc atgattgccc ttcatctgga aaagaaagaa
   103741 catctggatt aagctttctc taaggaaaac ttatactcaa tgaaaatcaa agagcaaact
   103801 aggaagctaa ccgcaggttg ctcaaaacac tgttttgagg ttgtggatga aactgacgaa
   103861 gtcagctcaa aacactgttt tgaggtggca gatagaactg acgaagtcag ctcaaaacac
   103921 tgttttgagg tggcagatag aactgacgaa gtcagtaaca tatatacggt aaggcgacgc
   103981 tgacgtggtt tgaagagatt ttcgaagagt attaagctag tttttaggtt tggctcttat
   104041 actaaagtca tcaaaaagaa acgaggactc tcatatgaca gtaacgatta aagtaaatta
   104101 ccaaatcact ttccaaaaga aggaagcaaa aaactagtat aaacagaaga gagagcgaaa
   104161 tgctcttttt tcgtttctaa aactactttc agcccatcat cctaaaagta aagaatctaa
   104221 attcactttc tatttaccct tctttcttgc attgattaca tagatatgct acagttgtgg
   104281 taacgattac aaaataaaag gagcatgcta tgaaaaattc agctttgcta gaagaaatta
   104341 agacctatag aggaagggat gaggttccgg aagactttga tgctttctgg gatggggaag
   104401 tgaaaaatgt ttccacgctt ccatcctacc acttggagga aagagatttc cacattcctc
   104461 aagtcaagtg ctatgagtta acatttgaag gaagcaagga aggaaaggtc tatgcacgca
   104521 ttgttcttcc aaagagtgag gagaaggttc cattaatctt ccattttcat ggttatatgg
   104581 gacgtggctg ggactgggcc gacatgctgg gcttcaccgt agctggttac ggtgttgttt
   104641 ccatggatgt gcggggccag tcaggttact cacaagacgg cttgcgttct cctttaggaa
   104701 ataccgtgaa ggggcatatt atccgtggtg ctatggaagg tcgggaccac ctcttttata
   104761 aggatgttta tctggatatt taccagttgg tcgaaattgt tgctagtctg tctcaggttg
   104821 atgagaagcg tctttctagc tatggtgcct cacaaggagg ggctctagct ctagttgcag
   104881 cagcgctcaa tcctcgaatt cagaaaacag ttgccattta tcccttcttg tcagacttca
   104941 gacgggtgat tgagattggt aatactagcg aggcttacga cgaacttttc cgttatttca
   105001 agtttcacga ccccttccat gaaacagagg aggaaatcat ggcgaccctt gcctatatcg
   105061 atgtcaaaaa tcttgcccat cgtatccaag gtgaggttaa gatgattacg ggcttggacg
   105121 acgatgtttg ctatcccatt acccagtttg cgatttataa tcgtctgacc tgcgataaaa
   105181 cctatcgtat catgcctgag tatgctcacg aagccatgaa tgtatttgtt aatgaccaag
   105241 tctacaactg gctctgtgga agtgagattc cttttaaata tctaaaataa ggagtcgact
   105301 ctaagcacaa aatcttaaaa attacaaaca cgcatagtat caggggatta agaaaacttg
   105361 atactatgcg ttttatcatg gaaatatagt gaaatgaaac aagaacagga caaatcgatc
   105421 aggacagtca aatcgatttc taacaatgtt ttagaagcaa aggtgtacta ttctagtttc
   105481 aatctattgt atttatagaa ttttttgttg ctagatttgt caaattgctt aaaataattt
   105541 ttttcagaaa gcaaaagccg atacctatcg agtagggtag ttcttgctat cgtcaggctt
   105601 gtctgtaggt gttaatactt ttcaaaaatc tcttcaaacc acgtcagctt cgcctt
//
LOCUS       DBEJZV010000002       102931 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.02, whole genome shotgun sequence.
ACCESSION   DBEJZV010000002 DBEJZV010000000
VERSION     DBEJZV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 102931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 102931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..102931
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.02"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(4..123)
                     /locus_tag="ACL3S0_000118"
     CDS             complement(4..123)
                     /locus_tag="ACL3S0_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
                     /protein_id="HGR1311118.1"
                     /translation="MSQSIVPVEIPQYCRFDSKKRNGILFNVRIANLKFIFLY"
     gene            complement(348..1208)
                     /locus_tag="ACL3S0_000119"
     CDS             complement(348..1208)
                     /locus_tag="ACL3S0_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGR1311119.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1224..2501)
                     /gene="spxR"
                     /locus_tag="ACL3S0_000120"
     CDS             complement(1224..2501)
                     /gene="spxR"
                     /locus_tag="ACL3S0_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGR1311120.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2494..3045)
                     /locus_tag="ACL3S0_000121"
     CDS             complement(2494..3045)
                     /locus_tag="ACL3S0_000121"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311121.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3061..4320)
                     /locus_tag="ACL3S0_000122"
     CDS             complement(3061..4320)
                     /locus_tag="ACL3S0_000122"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR1311122.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(5369..5527)
                     /locus_tag="ACL3S0_000123"
     CDS             complement(5369..5527)
                     /locus_tag="ACL3S0_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311123.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(5537..6847)
                     /gene="obgE"
                     /locus_tag="ACL3S0_000124"
     CDS             complement(5537..6847)
                     /gene="obgE"
                     /locus_tag="ACL3S0_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGR1311124.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVLVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLVTLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(6911..7045)
                     /locus_tag="ACL3S0_000125"
     CDS             complement(6911..7045)
                     /locus_tag="ACL3S0_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGR1311125.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7104..7280)
                     /locus_tag="ACL3S0_000126"
     CDS             complement(7104..7280)
                     /locus_tag="ACL3S0_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR1311126.1"
                     /translation="MRSGRDKKIAGVCAGVAYYLDMDPTIVRVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(7311..8636)
                     /locus_tag="ACL3S0_000127"
     CDS             complement(7311..8636)
                     /locus_tag="ACL3S0_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR1311127.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(8652..9695)
                     /gene="cpoA"
                     /locus_tag="ACL3S0_000128"
     CDS             complement(8652..9695)
                     /gene="cpoA"
                     /locus_tag="ACL3S0_000128"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGR1311128.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEENLLQIW
                     LDFYEKQAALGRK"
     gene            complement(9810..10139)
                     /locus_tag="ACL3S0_000129"
     CDS             complement(9810..10139)
                     /locus_tag="ACL3S0_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR1311129.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10153..11262)
                     /gene="rpoD"
                     /locus_tag="ACL3S0_000130"
     CDS             complement(10153..11262)
                     /gene="rpoD"
                     /locus_tag="ACL3S0_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGR1311130.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11265..13025)
                     /gene="dnaG"
                     /locus_tag="ACL3S0_000131"
     CDS             complement(11265..13025)
                     /gene="dnaG"
                     /locus_tag="ACL3S0_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGR1311131.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQDLYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13115..13873)
                     /locus_tag="ACL3S0_000132"
     CDS             complement(13115..13873)
                     /locus_tag="ACL3S0_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311132.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(13870..14736)
                     /locus_tag="ACL3S0_000133"
     CDS             complement(13870..14736)
                     /locus_tag="ACL3S0_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311133.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(14805..15809)
                     /gene="trpX"
                     /locus_tag="ACL3S0_000134"
     CDS             complement(14805..15809)
                     /gene="trpX"
                     /locus_tag="ACL3S0_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1311134.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(15922..16139)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16222..18918)
                     /gene="ppc"
                     /locus_tag="ACL3S0_000135"
     CDS             complement(16222..18918)
                     /gene="ppc"
                     /locus_tag="ACL3S0_000135"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGR1311135.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(18938..20167)
                     /locus_tag="ACL3S0_000136"
     CDS             complement(18938..20167)
                     /locus_tag="ACL3S0_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR1311136.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGLSVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(20295..20624)
                     /locus_tag="ACL3S0_000137"
                     /pseudo
     CDS             complement(20295..20624)
                     /locus_tag="ACL3S0_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(20747..21151)
                     /locus_tag="ACL3S0_000138"
                     /pseudo
     CDS             complement(20747..21151)
                     /locus_tag="ACL3S0_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918778.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
     gene            complement(21258..21866)
                     /locus_tag="ACL3S0_000139"
     CDS             complement(21258..21866)
                     /locus_tag="ACL3S0_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HGR1311137.1"
                     /translation="MKEQIFLMGGNPPIKNYTIVNKIVSSRKIERIVIFTVFRENWEP
                     YMKKYTEVFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEF
                     KSYIDHMLNKEAKIIGFSAGALLLGEKVYVSPNVNSDYQIKIKNGLGLFSQFLISVHY
                     DSWNDKANKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            complement(21950..23743)
                     /locus_tag="ACL3S0_000140"
     CDS             complement(21950..23743)
                     /locus_tag="ACL3S0_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGR1311138.1"
                     /translation="MKKNNVEIIKADSLVRRRGDNVERHLKRVAAYCRVSSDSEDQKN
                     SYDSQVRHYKEYISQRSDWELADIYADEGISGTQVGKRQDFQRLINDCANGEIDYIVT
                     KAIARFARNTLDTLKYVRMLKDMQIGVYFEEENIDTLTMDGELLLTILSSVAQQEVEN
                     TSAHVKKGLKMKMQRGELVGFQGCLGYDYDVETKQISINKKEAKIVRYIFERYLEGIG
                     GKVIARELDELGYKSPRGLEHWNDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLSN
                     FGEEDKYYIKDNHEPIISKEDFEKAQEIRLRRAGNKKTAANVNGKRERYSKMYAFSSM
                     LECGFCGSILSRRSWHCRSDYRKVVWHCVTSIKKGKKFCKHSKGLEEIAIEGAFLEAY
                     RQVYHSNENLMTDLLETIESELNDNSLNKELKRITNKLRILLKKEENLVNLRLEGKVS
                     DSIYNEKYNEISSEKEFLAEEKVNIETTLKSEIDVKKRLTEFKHLLSSQKMLTEFDRA
                     VFESIVEKIIVGGVNSNGEIDPAMLTIIFKTGEIQNKDGKQFKSKRKNAKLETDKLCP
                     QNSDEDKKLYSQGTDNTRGVCSVAGSILASQ"
     gene            complement(23910..24062)
                     /locus_tag="ACL3S0_000141"
     CDS             complement(23910..24062)
                     /locus_tag="ACL3S0_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311139.1"
                     /translation="MTTNKDNDTSERSGCQRKRTAGEMPMNDLTSHTHGGNYTCYKEE
                     KVWNNQ"
     gene            complement(24190..24396)
                     /locus_tag="ACL3S0_000142"
     CDS             complement(24190..24396)
                     /locus_tag="ACL3S0_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1311140.1"
                     /translation="MYIRLKNLREDKDLSQCQIAQYLHCSQSAYSRIESGKQDIPTSF
                     LKQLAKLYQVTTDYILEMDKFSCQ"
     gene            24898..26093
                     /locus_tag="ACL3S0_000143"
                     /pseudo
     CDS             24898..26093
                     /locus_tag="ACL3S0_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713014.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(26472..27257)
                     /locus_tag="ACL3S0_000144"
                     /pseudo
     CDS             complement(26472..27257)
                     /locus_tag="ACL3S0_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(27259..28078)
                     /locus_tag="ACL3S0_000145"
                     /pseudo
     CDS             complement(27259..28078)
                     /locus_tag="ACL3S0_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(28080..29072)
                     /locus_tag="ACL3S0_000146"
     CDS             complement(28080..29072)
                     /locus_tag="ACL3S0_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1311141.1"
                     /translation="MKMITVEHLQKNFVKTIKEPGLKGAFRSFFHPKRQVFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQENRQGYVKDIGVV
                     FGQRTQLWWDLALQETYSVLKEIYDVPDAVFQKRMDFLNEVLDLKEFIQDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLG
                     DIEQLCDRIFMIDKGREIFDGTVNQLKKTFGKMKTLSFELHPGQDYIVSHFEGLSDIY
                     VTRQELSLDIQYDSSQYQTADIIQQTLSDFTIRDLKMTDANIEDIIRRFYRKEL"
     gene            complement(30089..30865)
                     /locus_tag="ACL3S0_000147"
     CDS             complement(30089..30865)
                     /locus_tag="ACL3S0_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HGR1311142.1"
                     /translation="MNNLTLLKEYNFRDLGNHLTQTGQKIKPKTLFRSSKLFGISKID
                     VDLLQSYGITKVIDFRSANEIKKAPDPDIKNIKNIKNIVIPIFYNDDSELTEFPIEFF
                     NKSDAGFQHMIKTYDQMINQKQSKLGYKKFFKLLLSHPKDESLLFHCSMGKDRTGIAS
                     LFLLYILGVDMNDIFHDYLLSNKYLINVRKENIEYVNNHSGNVILMHNLLSLSSAKEE
                     YINRVLNVLDKEYGGILRYINTELGISSQEIEELKDRYLF"
     gene            complement(30966..32603)
                     /gene="metG"
                     /locus_tag="ACL3S0_000148"
     CDS             complement(30966..32603)
                     /gene="metG"
                     /locus_tag="ACL3S0_000148"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGR1311143.1"
                     /translation="MSIFIGGAWPYANGSLHIGHAAALLPGDILARYYRQKGEEVLYV
                     SGSDCNGTPISIRAKKENKSVKEIADFYHKEFKETFEKLGFTYDLYSRTDSPLHHEIV
                     QELFLQLYEKKFLYTKKIKQLYCTFDNQFLPDRFVEGKCPNCGTHSRGDQCDNCSAIL
                     DPIDLVDKRCSICSNEPEVRETEHFYYVFSEFQNLLETYLNDAEETVRWRKNAINLTK
                     RYLREGLPDRAVTRDLPNGIPVPIDGFRDKKIYVWFEAVAGYYTASVDWAQKLQNNIT
                     DFWNNRTKSYYVHGKDNIPFHTIIWPAILSGLEIEPLPEYIISSEYLTLENKKISTSN
                     NWAIWLNDIIKKYDADSIRYFLTINAPEMKDANFSWREFIYSHNSELLGSYGNFINRT
                     LKFIEKYFESEIPTKYLEGEILYNLKELYTTVGNLVESGHMKQALEEIFEYIRSANKF
                     YDDMKPWALRESDIEKCKEVLATCVIIILNLGQMLNPFIPFSGKKIEDMFKTKLNTWN
                     YISNLPNKLSDVSMLFDRIDLKKIDEEVLELQQTSSR"
     gene            complement(32671..33306)
                     /locus_tag="ACL3S0_000149"
     CDS             complement(32671..33306)
                     /locus_tag="ACL3S0_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatA-like O-acetyltransferase"
                     /protein_id="HGR1311144.1"
                     /translation="MTFPISEWKRNEEFDFFNKMDVPYLSMSSRIEVTQAINFHKKHS
                     ISLYAIISWCVMSAINSIPELLMDTDGKIVWQYNQRGCSFTTLTSEDKLNFSSFTMGD
                     NLIEFVSAFNINKQKAEEGQKPNIDKNNIAYLSCVPWIDFLHVSTPMNLSKIDTVPRI
                     TWGKVIQENQRYFCTVNLQINHGMGDGLHVSNFFVLLQRFVNKINEYFQKK"
     gene            complement(33303..34700)
                     /locus_tag="ACL3S0_000150"
     CDS             complement(33303..34700)
                     /locus_tag="ACL3S0_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311145.1"
                     /translation="MKIKDSAEILNNNMKLSSDLNILIRQLSYFIKDKEMLQQKIFGN
                     FLDRFEEAYEQHFFDIFDSLTGGIKISDVDWILGEEKLIKFLGRKNKNGQYLYVLPTN
                     DGYLLRGSETYYHYLSNVPYDYFKLIDKNIFIDGLKSTQNFLTEFIQYINSENSLTLK
                     ISLAFLDNLRNQILILLNAKFLVENDFKHGKYYVNFDSKLFKAIELFYSYYEKLFNFK
                     HFILQPEDLVVILDILNSEIEALIPKLKNLDNNKVRKLTRVFRELDSIWEIFISLKYF
                     FESENSLDVDNISEFCGIAYGGIEIPLVAHLFKEKNEISFLFQNSHYSTQEVEVKRFR
                     DSRRNDSKSILLMDDNILTGRAMKNAAQKLSYRKYSVQFFHVRRLGLNRLSQVIQENS
                     MNELQRYLTGIYKGGIFPAPYSKIKFGTNIAKQYLDELQIFTLSGDEILRLLYKNGLF
                     SEESEVKVVRGNLYE"
     gene            complement(34704..36437)
                     /locus_tag="ACL3S0_000151"
     CDS             complement(34704..36437)
                     /locus_tag="ACL3S0_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGR1311146.1"
                     /translation="MNELCKKYVYQLQNELNQYCDNLEGIHVIAYGSNGSNDLSISSD
                     FDVCLIVNDDSFVAMNQRLICDFTKLFHFQENLPIDKDIPLSNKLIYLSSEVELFLDN
                     PPFISDSKKVKIEDIKKTKNFLTSRTMKQRLLLNILTTDSTVLFGDEDYVNNLKYRAW
                     EDIEKIIERAYNIKLTTKNENEFLNLLYQNPVSKASGEYYLGYKKEKRNVVKHLERNV
                     HRLAILNEKKVEDIIDLSENVNRLLLKDYSFLFPSETIKKMISTYPEKKSCSIKEVLS
                     SKLTIASNNFLITNGSLEGMNIIIANLVQNNIGYLTPTFWGYGDSAKRYNKSVISAPL
                     SDIYNYNVTEIDKISKSCELMIICNPNNPTTATLTKNQIENLLLNNPQTYFLIDESML
                     PYKYDFFNYTMIPFVEKYTNLIVCSSISKSLCAPGLRIGYICANEKIVKKLEKKVIPF
                     NVSNINQCIAEKILENFPLSLSICSDIESSFRQLDLFMEKYTTQKSEKACGFRLYQLK
                     AKYDGNKIIDILTERGFLIRNISASYPELGENWIRISNGTLSEIKDLMHIMKDIFEDF
                     DDKASDSYDKG"
     gene            complement(36430..37902)
                     /locus_tag="ACL3S0_000152"
     CDS             complement(36430..37902)
                     /locus_tag="ACL3S0_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="HGR1311147.1"
                     /translation="MSKELYNKFILTKEAGNIIYDGIEFGRDEIDRRILEISKILTAD
                     IVNLSQEAVAISCNKKINFFFLFLVVNCCDGVVMPVYARTPENKLQHICERYDINYMV
                     SDHEINLVGYSLIYHGSVFSEEYFIYECNKSFPKHEELKGIELLMLSSGTTGVSKAIS
                     LSLDNILSNTRSIQKYIIPTREDRCLIIKEITHSSSLISELINSLLSKNSVLLSDLIP
                     TVSSLGYLISTYGVTILYAIPDFLLFMNSIKFINNYRQLLGKLRLVQVVGAFCPPNYI
                     TDFHKNWPKIDLFNGYGLTEASPRVAVLGGEELYANPRCVGYPISGVGVHIDTSSNNT
                     QEGEICVTGPNIMVEYYLNEELTSKIKIGGMLRTGDIGYFDDKNRLYILGRKDNRYIK
                     SGKNIFPEEIESVVRKLPFISEVIVYPKIESGRLISILEYTICNDEEKDLNQEASEII
                     KLCKDNLEDYKIPDQYRKVKNIPHTSTGKVKRDRNNYYNE"
     gene            complement(37906..39411)
                     /locus_tag="ACL3S0_000153"
     CDS             complement(37906..39411)
                     /locus_tag="ACL3S0_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HGR1311148.1"
                     /translation="MDNENEISKFFLSSENVKDMKTIANDILNMGLDFKLSEKVSQKK
                     MKEHDDLNFLSLEESIDNLPQLLEEFREKVIPYCTNFSSPNFMGFPDSGNSLGGLSGS
                     LLSDLLQQNLINASFCAPVATIMEINVIQWLRKVLGYSTSDVHNIMEVGGIVTYGGTG
                     SNSTAMLLARENKDGNTLELGVRNPRNYKVIVPKGIGHYSIASSLKWLGLGNNIIEVP
                     TENYRYNLKKLREALINHSNEIMAVVAYAGDSRTMTIDNLSEVADLVKTLTPNVWLHC
                     DACHGFSLAFSKKYKDRIKGIEKFDSISTDPHKVLGIPYCISVLLVKTPQSLNLIHSQ
                     SDLIMNENLALGQTTPFLGSKSWISLKLWLVAKHLGSEKIGAMVDKRIELTNYLQDLI
                     LKSSKLILLNRTDINSVMFMYIGDKHQEVSLSSVQNINNINKSIYDRLKDEGIYYLHQ
                     FPIIDNTETIYRGFELCPLRFMSGNPNLTIEELQKMVIEVENLGDRFVGES"
     gene            complement(39427..40617)
                     /locus_tag="ACL3S0_000154"
     CDS             complement(39427..40617)
                     /locus_tag="ACL3S0_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000982805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311149.1"
                     /translation="MMPQITQFLNNIKNNNEYYSNIINDATVLDDIPILNKNDIRLNP
                     DSIISECYSKKDLIHETTNGTTDYHPLDLYKTPQERVDLNFSLWKERRKFISASNIKS
                     VKIAVFYYSHDSLMNHDGSLKKVSGLIQVPMNRADDNQYIADLKYLIEEEIKWLIGPV
                     SIFLKYAKICKKYCIKFNVEYCECTSEYVPEVYRKEIEDVFKCKFLMQYSCHELWGIA
                     FTNSLEMYNVLKPLDNSIVEGLLRKEFTSKKLYSPVVTSLTLKAMPFIKYLLTDLVYF
                     DNGYIIPFGFRYTDMVKLKTDTIHCSIFDNLFGTLPFKFEPLEQYQIIYDAQNSEIVV
                     NVLNLEVTQGDIVCSVLKEYIKEHYKSSIKVSLRNCSKFFRDNLTGKMRGIINKENIN
                     NEIW"
     gene            complement(40614..40871)
                     /locus_tag="ACL3S0_000155"
     CDS             complement(40614..40871)
                     /locus_tag="ACL3S0_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR1311150.1"
                     /translation="MDIRKKIIELCIKINPHLEDHYFYDYEKMIDDLDFDSLTITQLV
                     IDIEEQFDIMLPPQKISMSEMETFGKIVDLVHKCITSKESR"
     gene            complement(41223..42272)
                     /locus_tag="ACL3S0_000156"
     CDS             complement(41223..42272)
                     /locus_tag="ACL3S0_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311151.1"
                     /translation="MIELKIGKPSFGFLPYESHIEGILTGNNLNKIDYYLSMLDMEAI
                     CLQYGNKRIYDFFIGRNIQCNNIYREYSSRIDLSSEEALIPFLVDALAKGSFCYLSVD
                     TFCINKYISYKKEHIVHSPLVSGIDLDRNLIKISDFFDFTNYGIVWVPINEFIKGYFA
                     IQKVVEEGDIEETENWILKIEKINICKNKTEICDRMAINKVFKGYVLGSEEVKNSMDT
                     FSYINYRLANHKVFQKQSIVEQNLSVTGIKVYEYLKLYIEESIKEPQVLMRIKNLVLL
                     KKHFDVYKKIVQVLGINSEKVQACIEKAQLFLLIGMKINRSNQINNKLYFDMISIVRE
                     LKEMEYEIISEILSM"
     gene            42502..43316
                     /locus_tag="ACL3S0_000157"
                     /pseudo
     CDS             42502..43316
                     /locus_tag="ACL3S0_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
     gene            43675..44628
                     /locus_tag="ACL3S0_000158"
     CDS             43675..44628
                     /locus_tag="ACL3S0_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HGR1311152.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASSNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            complement(45321..46740)
                     /locus_tag="ACL3S0_000159"
                     /pseudo
     CDS             complement(45321..46740)
                     /locus_tag="ACL3S0_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886556.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(46996..48846)
                     /locus_tag="ACL3S0_000160"
                     /pseudo
     CDS             complement(46996..48846)
                     /locus_tag="ACL3S0_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261804.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
     gene            complement(48833..49198)
                     /gene="mobC"
                     /locus_tag="ACL3S0_000161"
     CDS             complement(48833..49198)
                     /gene="mobC"
                     /locus_tag="ACL3S0_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HGR1311153.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIDKSHCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSRLISQEQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSY"
     gene            complement(49208..49567)
                     /locus_tag="ACL3S0_000162"
     CDS             complement(49208..49567)
                     /locus_tag="ACL3S0_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HGR1311154.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSSFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            complement(50003..50275)
                     /locus_tag="ACL3S0_000163"
     CDS             complement(50003..50275)
                     /locus_tag="ACL3S0_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311155.1"
                     /translation="MKKVDGYRLLNKPDHAVLLFPLTVIIFVLLGACFFKPHFHNSFR
                     GYYSKIDCGIAIQSTGLQIYGDTVFVDGAIYELNEVTMQILDNEKT"
     gene            complement(51818..52585)
                     /locus_tag="ACL3S0_000164"
     CDS             complement(51818..52585)
                     /locus_tag="ACL3S0_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA helicase"
                     /protein_id="HGR1311156.1"
                     /translation="MDNKRLIHAVAGSGKTTKIIETIDPQKRNLILTYTETNQNTIRA
                     KLIEKFGYIPESTFIFGVFESLYSFCLVPYLGKRPKGINFDYKTQGKFDKTAIDNTGR
                     IVQNQLSKSLLRGSLIYKRKEIRFDNSYLDRIDKFFDCIYVDECQDFESDDFDWLLSL
                     SNLNAEVFLFGDYYQKTFSTSRRGNKGKRIHSSFENWLKVISDSGYEIDLSSLSKSYR
                     CPKIVCDFIVDNLAIEILSQREEKLSSQITLIDSQKK"
     gene            complement(52567..54156)
                     /locus_tag="ACL3S0_000165"
     CDS             complement(52567..54156)
                     /locus_tag="ACL3S0_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014334739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR1311157.1"
                     /translation="MISRIILQNFKRYQNVDFTCNSEVNIFVGENGAGKSTLLYGIGL
                     VLSGSHSQIERSSLSSIINQEAILEFMGTRDINQLPEVFIEIYFDELSTEISSNFNIE
                     GKHNSQKIKAFGLSLKIIPNQDYIAEITSVLNDSKWTVFPFEFYRVEFLTFSGKTYSS
                     YNKPYKFLHSMINTSLIDTQQEIQKRIHEVYLDNISAENRAKVNHQYRINSFNFLKTL
                     RKDELLKENASEFQLHFDESENSFRNSVSAVKNGVDIKNLGQGEKVLLGVENAYSHLK
                     ETVKILLIEEPENHLSFQNLQKLVRMLSSNTGVQVFIGTHSNMIASRLGVDNLLFLDN
                     GQISKLKGLKKDTVRFFKKSTNQNLLNFSLGKKIILVEGNAEYILVEKFFEILHSKKP
                     EEFNVSIISVDGLSFERYLEIATNFTDKKVVVITDNDGDYESKVQSKYSSYQQFQNIK
                     VSSDLDNDNRTFEICIYNCNSDLLESSGLTKSNDLLEYMLREKAEFALRLLEQMETDN
                     IREKFIIPNYIKEAIEWIIKD"
     gene            54560..54778
                     /locus_tag="ACL3S0_000166"
                     /pseudo
     CDS             54560..54778
                     /locus_tag="ACL3S0_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466054.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            complement(54944..55924)
                     /locus_tag="ACL3S0_000167"
     CDS             complement(54944..55924)
                     /locus_tag="ACL3S0_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR1311158.1"
                     /translation="MKLLKKTMQVGLTAFFFGLLATNTVFADTTGGQFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGNKGEMVVGWQYLEIPGTGYRDNLLDNQPVNEIGLQHKW
                     YYFGQDGSLQEYVGWKELDAKDSLNVGKEYGEPFEGPEVLKYANYYFDKDHSLKTGWF
                     YDQSNWYYLAKTGYLGKDYLGGERRAGWIYDGSSWYYLDTTTAAMQTGWQYLGNNWYY
                     LRSSGAMATGWMKDASTWYYLDGQNGDMKTGWAYVGNSWYYLRSSGAMSTGWMKDGST
                     WYYLNASNGDMKTGWFQVNGKWYYAYGSGALAVNTTVGGYYVNYNGEWVK"
     gene            complement(55943..57256)
                     /locus_tag="ACL3S0_000168"
     CDS             complement(55943..57256)
                     /locus_tag="ACL3S0_000168"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like serine protease"
                     /protein_id="HGR1311159.1"
                     /translation="MKKNFYKKLGISIIASTLLASQLSTVSALTVISSTGEEYEVSET
                     LQESPGTNNFSLPDISPTYGKYYTNQSEVIIGNNDLVKIGNTLQYPYSTSAYVKAEFN
                     SMNASFRGSASFIRDNVLVTAAHVVYDRDSRTEADSVYVIPAATPNENPVGKIKVKEV
                     RYLKEFQNTASNELTTYDLAVLILEEPIGAQLGTLGLPNNLGNLSGTGATITGYPAVN
                     SAKQMYTDSKDIVKDTGDFLMYQIDTLGGASGAGVYDSSFRLIGVHVSGSSAGQMNSA
                     VKLNEKALSFIYSVIQGHSIDGWKLISGTWYYYKNSTKQTGWQKINDTWYYLDASGKM
                     RTDWEKVNGKWYYFESSGSMATGWKYVRGNWYYLDNKNGDMKTGWYKDGSTWYYLDPT
                     NGNMKKGWIKVGGNWYYLNSSGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(57515..57799)
                     /locus_tag="ACL3S0_000169"
     CDS             complement(57515..57799)
                     /locus_tag="ACL3S0_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311160.1"
                     /translation="MEIKKVMYYNTVPQFLKPKLNYFARDFLNDYSVQIEDIEAGSNF
                     EVDVEYEGNLEVYFVKFMFRKKGGGMFSGNSENELDIYCNNELSATVILE"
     gene            complement(57828..59597)
                     /locus_tag="ACL3S0_000170"
     CDS             complement(57828..59597)
                     /locus_tag="ACL3S0_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HGR1311161.1"
                     /translation="MANNRQIETLGVSYLTTFINRHSLLQTYFGSNDKTPVWDGEIHV
                     LKTSSEKRSEIFGKVPVQIKATRQQKNKLKSFSLDISDLELYSKNGGVVLFVVWLSED
                     GDLRNIYYKSLPPLSIKKLIKKSNLKNKTTSSKKLSVQIHELDEQKLYPMLVDFITNS
                     RKQYSFINVDGISVEDISDDSNLKFYYYGQEKGEIFNYQEENDLFIYYKNPLTGIEVP
                     LENTIKVVETYEETDLIITIGNTIFQNVKRHRFPDGSVQLHFGEGFKMSFDVKKKQFT
                     FNYTRPNMLSKAIKCTQAFQELGKFGYCKLNGNIIELDEQSILDITSRDLETEIEELV
                     QISNFMENMRIQKEVDLTYFDKQSLRNLNILNLGLILKNKVALNYNESKLLHLRIANI
                     HIITLYDFETDNIGTMIDIFTETPWCRRGEGEDSSYISIFEVLEPNDWLKIDNCDFDS
                     VISSYQRLVDNGLKFEDANNTIIKIVIAADKAEDVSRSELLLNWAQCLSDWNLKYSKN
                     CEMAIINDLQIKSRVRKLNSKEMEILSNILVNSNDNYELCFGSSVLLKSKPQADLFWN
                     KLDNETKESYKEFPIYTLYMKLL"
     gene            59927..60823
                     /locus_tag="ACL3S0_000171"
     CDS             59927..60823
                     /locus_tag="ACL3S0_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR1311162.1"
                     /translation="MDYKLISTYLDYCKTHKRLSSHTIRAYKNDLMQFYNSDYDHVES
                     YIEHLTQSNIKTNTLRRKIACMKVFYNYLKYQNIIEENPFNQLRFQFRTEKILPKTIP
                     YDILKNIFIYLEQKVVISKTDYQKQKAERNLLIISLLLSTGIRISELCHIHLKDINLS
                     NKTLHIIGKGKKERILFLGDQTTFNILETYINKTGKESNDFLFPGKHLPKPLSEQSVR
                     LILKRIVEQNSLSKTITPHMFRHSFATMLLDNDVDIRYIQQILGHSSISVTQIYTHVS
                     HSKQKEILSSFNPMSVIHSEIE"
     gene            complement(61221..61979)
                     /gene="pezT"
                     /locus_tag="ACL3S0_000172"
     CDS             complement(61221..61979)
                     /gene="pezT"
                     /locus_tag="ACL3S0_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HGR1311163.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFESIQIYQRDRSCVYDSKENTT
                     SAATVLHDLLFGELNQVEKEMLKSGEERLKDLTN"
     gene            complement(61979..62455)
                     /gene="pezA"
                     /locus_tag="ACL3S0_000173"
     CDS             complement(61979..62455)
                     /gene="pezA"
                     /locus_tag="ACL3S0_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HGR1311164.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(62900..63355)
                     /locus_tag="ACL3S0_000174"
     CDS             complement(62900..63355)
                     /locus_tag="ACL3S0_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311165.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(63630..65369)
                     /locus_tag="ACL3S0_000175"
                     /pseudo
     CDS             complement(63630..65369)
                     /locus_tag="ACL3S0_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
     gene            complement(65532..66416)
                     /locus_tag="ACL3S0_000176"
     CDS             complement(65532..66416)
                     /locus_tag="ACL3S0_000176"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR1311166.1"
                     /translation="MKKVMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(66528..67382)
                     /locus_tag="ACL3S0_000177"
     CDS             complement(66528..67382)
                     /locus_tag="ACL3S0_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGR1311167.1"
                     /translation="MLGVIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVT
                     EAIMNGGQKDDFIDAMKKYGSMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(67440..68198)
                     /locus_tag="ACL3S0_000178"
     CDS             complement(67440..68198)
                     /locus_tag="ACL3S0_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR1311168.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNETHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(68260..68448)
                     /locus_tag="ACL3S0_000179"
     CDS             complement(68260..68448)
                     /locus_tag="ACL3S0_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGR1311169.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(68770..69336)
                     /locus_tag="ACL3S0_000180"
     CDS             complement(68770..69336)
                     /locus_tag="ACL3S0_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311170.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(69604..71283)
                     /locus_tag="ACL3S0_000181"
     CDS             complement(69604..71283)
                     /locus_tag="ACL3S0_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGR1311171.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEDRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNATIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            complement(71375..71536)
                     /locus_tag="ACL3S0_000182"
     CDS             complement(71375..71536)
                     /locus_tag="ACL3S0_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311172.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(72220..72519)
                     /locus_tag="ACL3S0_000183"
                     /pseudo
     CDS             complement(72220..72519)
                     /locus_tag="ACL3S0_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(72500..72889)
                     /locus_tag="ACL3S0_000184"
     CDS             complement(72500..72889)
                     /locus_tag="ACL3S0_000184"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR1311173.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(72942..73126)
                     /locus_tag="ACL3S0_000185"
                     /pseudo
     CDS             complement(72942..73126)
                     /locus_tag="ACL3S0_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(73277..74071)
                     /locus_tag="ACL3S0_000186"
     CDS             complement(73277..74071)
                     /locus_tag="ACL3S0_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311174.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHINS"
     gene            complement(74071..75078)
                     /locus_tag="ACL3S0_000187"
     CDS             complement(74071..75078)
                     /locus_tag="ACL3S0_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGR1311175.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(75078..76085)
                     /locus_tag="ACL3S0_000188"
     CDS             complement(75078..76085)
                     /locus_tag="ACL3S0_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGR1311176.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(76075..77100)
                     /locus_tag="ACL3S0_000189"
     CDS             complement(76075..77100)
                     /locus_tag="ACL3S0_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR1311177.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(77493..77711)
                     /locus_tag="ACL3S0_000190"
     CDS             complement(77493..77711)
                     /locus_tag="ACL3S0_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1311178.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(77957..78235)
                     /locus_tag="ACL3S0_000191"
     CDS             complement(77957..78235)
                     /locus_tag="ACL3S0_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311179.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAVYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(78449..80080)
                     /gene="rlmD"
                     /locus_tag="ACL3S0_000192"
     CDS             complement(78449..80080)
                     /gene="rlmD"
                     /locus_tag="ACL3S0_000192"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR1311180.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(80154..81128)
                     /locus_tag="ACL3S0_000193"
     CDS             complement(80154..81128)
                     /locus_tag="ACL3S0_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGR1311181.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(81202..81816)
                     /gene="pmp23"
                     /locus_tag="ACL3S0_000194"
     CDS             complement(81202..81816)
                     /gene="pmp23"
                     /locus_tag="ACL3S0_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGR1311182.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     QDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(81816..82790)
                     /locus_tag="ACL3S0_000195"
     CDS             complement(81816..82790)
                     /locus_tag="ACL3S0_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGR1311183.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(82798..84054)
                     /gene="glyA"
                     /locus_tag="ACL3S0_000196"
     CDS             complement(82798..84054)
                     /gene="glyA"
                     /locus_tag="ACL3S0_000196"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGR1311184.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(84116..84547)
                     /locus_tag="ACL3S0_000197"
     CDS             complement(84116..84547)
                     /locus_tag="ACL3S0_000197"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311185.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(84549..85151)
                     /locus_tag="ACL3S0_000198"
     CDS             complement(84549..85151)
                     /locus_tag="ACL3S0_000198"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGR1311186.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(85135..85974)
                     /gene="prmC"
                     /locus_tag="ACL3S0_000199"
     CDS             complement(85135..85974)
                     /gene="prmC"
                     /locus_tag="ACL3S0_000199"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGR1311187.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(85974..87053)
                     /gene="prfA"
                     /locus_tag="ACL3S0_000200"
     CDS             complement(85974..87053)
                     /gene="prfA"
                     /locus_tag="ACL3S0_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGR1311188.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(87050..87640)
                     /locus_tag="ACL3S0_000201"
     CDS             complement(87050..87640)
                     /locus_tag="ACL3S0_000201"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGR1311189.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            87763..87945
                     /locus_tag="ACL3S0_000202"
     CDS             87763..87945
                     /locus_tag="ACL3S0_000202"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGR1311190.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            88082..89455
                     /gene="mnmE"
                     /locus_tag="ACL3S0_000203"
     CDS             88082..89455
                     /gene="mnmE"
                     /locus_tag="ACL3S0_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGR1311191.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQIEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(89502..90437)
                     /gene="dapA"
                     /locus_tag="ACL3S0_000204"
     CDS             complement(89502..90437)
                     /gene="dapA"
                     /locus_tag="ACL3S0_000204"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGR1311192.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(90493..91569)
                     /locus_tag="ACL3S0_000205"
     CDS             complement(90493..91569)
                     /locus_tag="ACL3S0_000205"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGR1311193.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEKSTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(91912..91984)
                     /locus_tag="ACL3S0_000206"
     tRNA            complement(91912..91984)
                     /locus_tag="ACL3S0_000206"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91949..91951),aa:Thr,seq:ggt)
     gene            complement(92084..92593)
                     /locus_tag="ACL3S0_000207"
     CDS             complement(92084..92593)
                     /locus_tag="ACL3S0_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGR1311194.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(92591..92687)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            92716..93147
                     /locus_tag="ACL3S0_000208"
     CDS             92716..93147
                     /locus_tag="ACL3S0_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGR1311195.1"
                     /translation="MKIPIQKFFNNEILAYLFFGIVTTLVAILLRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            93229..93606
                     /gene="mscL"
                     /locus_tag="ACL3S0_000209"
     CDS             93229..93606
                     /gene="mscL"
                     /locus_tag="ACL3S0_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGR1311196.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(93648..94742)
                     /gene="hemH"
                     /locus_tag="ACL3S0_000210"
     CDS             complement(93648..94742)
                     /gene="hemH"
                     /locus_tag="ACL3S0_000210"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGR1311197.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSKQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            94897..96120
                     /gene="pepT"
                     /locus_tag="ACL3S0_000211"
     CDS             94897..96120
                     /gene="pepT"
                     /locus_tag="ACL3S0_000211"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGR1311198.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIESIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(96156..96809)
                     /locus_tag="ACL3S0_000212"
                     /pseudo
     CDS             complement(96156..96809)
                     /locus_tag="ACL3S0_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            96807..96971
                     /locus_tag="ACL3S0_000213"
                     /pseudo
     CDS             96807..96971
                     /locus_tag="ACL3S0_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(97048..97604)
                     /locus_tag="ACL3S0_000214"
                     /pseudo
     CDS             complement(97048..97604)
                     /locus_tag="ACL3S0_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672611.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(97711..98271)
                     /locus_tag="ACL3S0_000215"
                     /pseudo
     CDS             complement(97711..98271)
                     /locus_tag="ACL3S0_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672571.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(98497..101085)
                     /locus_tag="ACL3S0_000216"
     CDS             complement(98497..101085)
                     /locus_tag="ACL3S0_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGR1311199.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTPSPSLPINPGTSHEKHEEDGYGFDANRIIAED
                     ESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSNAKE
                     MKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVGIGH
                     SHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVSFSF
                     PPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFKYTI
                     ASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDALVRV
                     FDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYIVEV
                     PILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTSNST
                     LEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTGEAP
                     QGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPEGNV
                     GSDPMLDSALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVIKKN
                     LSDLIA"
     gene            complement(101295..>102931)
                     /locus_tag="ACL3S0_000217"
     CDS             complement(101295..>102931)
                     /locus_tag="ACL3S0_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGR1311200.1"
                     /translation="LIFDPAQITSRTARGVAVPHGNHYHFIPYSQMSELEERIARIIP
                     LRYRSNHWVPDSRPEQPSPQSTPEPSPSPQSAPNPQPAPSNPIDEKLVKEAVRKVGDG
                     YVFEKNGVSRYIPAKNLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAY
                     DLLARIHQDLLDNKGRQVDFEALDNLLERLKDVPSDKVKLVDDILAFLAPIRHPERLG
                     KPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDS
                     LSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNL
                     QYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERP
                     HSDNGFGNASDHVRKNKADQDSKPDEDKEHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVENSVINAKIADAEALLEKVTDPSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT        31792 a        20535 c        15949 g        34655 t
ORIGIN      
        1 agtctaatat aaaaaaataa atttaagatt ggcaatacga acgttaaaca gaattccatt
       61 tctcttttta gaatcaaaac gacaatattg tggaatctct acaggaacaa tagactgcga
      121 cactaaaata tcctccctta gttttacttt actaatagta tataggagga gagccctgaa
      181 tcctagaccc tttgttatga tgcgcttaca aacagagttg gaaaaaatct taaaagcaga
      241 aaaacgcatg atatcagccc ctaacacttg atacaatgcg ttttattatg aaaaaatcta
      301 ctggattttt tatcaaaata aacttccagt agtcttttca ctttttatta ataagttcct
      361 tcttcacctt ggctagtcaa gataacaggt ccatctttcg taatgacaaa ttggtgttca
      421 tactgacatg acaatccacc gtcaatggtc ttatgcgccc aaccagtttt catatctgta
      481 tcaatttccc aatcgcctgt attgatcatt ggttcaatgg ttaagaccat tccttcacga
      541 agacggagtc cacgacctgc aataccatag ttaggaacca ttggttcttc gtgcatagtt
      601 gggccaacac catgaccaac caaatcacgc actacaccgt aaccacgact ttcagcgtat
      661 tcttgaatag ccgcaccgat atcaccgata cgatttccaa caacagcttg ctcaataccc
      721 ttgtacatag cttctttggt tacatccatc aagtttttga cttcttcgga cggtgtacca
      781 acagcataag cccaacatga gtctgctaaa ccaccagaat agctctgagt gtattttttc
      841 atttgttcaa cattgttgaa gtttaatttt gagacattta ggtcagattt agcaatggga
      901 cctcccaaaa ccatatcaac tttgagcaaa tcaccatctt tcaagatata atgacgaggg
      961 aaagcgtgag ccacttcatc gttaagagag caacaggtag cataaggata gtccatcatg
     1021 gcaccgtcaa ccccaatctg aagtggaagg aaattttctt ctttacaacg acggcggaca
     1081 tattcttcaa cttcccacat atctacgcct ggcttaatca aatcacgtaa gcctatatga
     1141 atacttgcta gaaaatcacc agccttgtcc atagcttcga tttcacgagc tgattttaat
     1201 gttatcatct tttctcctag tttctaatta attttaacag tcacatttgc ttttgaaaca
     1261 atctggtgac catgataaat atcgtaatca attatagctg accgtctcgt atgatgaata
     1321 atccgtgcct gaatgcgcaa tatatcatct atctgaacgg cctgcaaaaa gtagatcagc
     1381 atctgctcga taatgagatt gcgaccacta ttaacaacta aatcttgggt catgtgggtc
     1441 agaatttctg ccaatacacc attagccaaa actccatttt tttctagcat aaagggttcc
     1501 actgtaatga ctacttcatc atggtgataa gagagctttt gtccaatctg ctcagaaaaa
     1561 gttggtagag ccgaaacttg ggaacggctc atcttctcca tgacatctcg tcgcgtcaca
     1621 acgccaagca aagtttgatt gcttcgaaca actggtacca tttcaaagtc ttctgcgatc
     1681 atccgttgac tcacattggc aatatttgtc gataatccaa ccaaaaatag actacgagac
     1741 ataaccttat caattgtcgt gcttggtgat ttatcaccag cgtctctcat ggttacaacg
     1801 ccaacaacga cctgatgttg attgataaca gggaaacggc tgctacgatt cttacgaacc
     1861 aagtccaaat aatctttaac tgtatctgtc tctctcagaa aaccatactc atgactaggg
     1921 cgataaagtt tctcaactgt cagaatatca gtcttgattt ggacatttga caaggcttta
     1981 ttgatcatgg tagcgacggt aaaggtatca tgcttacttc ttagaacagg aatccctttt
     2041 tgattggcca gtttaagcac atcatcatga acctgaaatc cccctgtaac cagaactgca
     2101 ttttcatttt ccaaggctag caactgaata cgggttcggt ctccgacaat caagagcccc
     2161 ccatcatgaa ggtaagacaa gatattttgt tcagtcatgg caccaattga aaacttacta
     2221 aattctctct ctaaaccttc ttgcccagcc agaacctcag aagaagtcac ttctgcaatt
     2281 tcagcaaacg ttaatctatc tatagcaact ttctgggatt taacacgaat tgttccactt
     2341 ctaggacggg tctccacaat tccacggttt tcagcttctt taatagctcg ataggctgtt
     2401 ccatcactaa ctcctagatg attcgaaatg ctacgaacac tgaccctttt acctactggt
     2461 aattcctcca aatagcttag aatttcctga tgcttactca ttgaactctc cttttacata
     2521 ccgaaattca agataatccc gcatttttct tgtgtaacga tcacttccct taaactgacg
     2581 gaacaaacta aatccagact taagagcaac tctttggcta gcttcatttt caaggtgggt
     2641 aatgataaat aattgtttta agccaaattc ctcaaaagaa agctgacaaa tttttctaac
     2701 aacctctgtc ataaatcctt gcgaccaagc atcttttctc aaaaaatagc caagctcagc
     2761 ttcttttttg atttcatcta acttctcaaa tttaatagaa ccaatcattt gttgattttt
     2821 ctggtcacaa attgcccaca ctcccaaagg ggacttcata aagtaattgg ccagtgcata
     2881 ttgactttct tccagacttg cctgcgttgg gaaaataaat tgaagatttt ctggatttga
     2941 agctatctcg cggaagtcct gactatcact aaaaaagaaa ggacgcaaat acaagcgatc
     3001 cgtttcaaaa aaagaaaaca ttgctaattt ggtccaaata ttcataaaca cctctacggt
     3061 ttaatcctca acaagtctaa tatccgctcc taaattacgt aatttttcga taatatcaga
     3121 ataaccacgt aagataaact cgatattggt aatttcagtt ttaccttcag ccataagccc
     3181 agcaatgact agtgcagccc cagctcttaa gtcggtcgct ttaacactgg ccccacgtaa
     3241 atcacgtcca cccgtgtaca aaatatgacc atttgttgtc gaaatatccg catccatctt
     3301 tgctagttca aaaacatgat ttacacgttt ttcgtaaatc gtatcgacaa ttgtaccacg
     3361 accattcgct cttagtaaaa gaggggtaag cggttgttgc aaatcagttg caaagcctgg
     3421 gtaaggagct gtcttaatat tgattgcttt caaattagac tgttcctcga caaaaatgct
     3481 gtcttcagat acagtcattc tcactcccat ttcttccaac ttagcaataa acccttccag
     3541 gtgttcgtaa agaacattat ttatacgaat tcctttacca actgcagcag ctaaagatat
     3601 atatgttcca gcttcaatgc ggtctggaat cacctgatga cgtgtcccat gtaatctttc
     3661 aacaccatca ataatgatga tattagttcc tgccccacgg atatgggcac ccatattatt
     3721 caagagagta gctacatcaa taatctcagg ttcacgggct gcattttcaa taatagtacg
     3781 accatttgct ttaaccgcag caatcatcgt attaatcgtt gctcccacac taaccgtatc
     3841 catgtaaata cttgcaccat gaagtcctgt atctttagca gataacttca tgttatctcc
     3901 ctcgtagcta gcagtggcac ccatagcttc aaacgcctta aggtgtaagt caatcggacg
     3961 aggaccaaga tcacatcctc ccggtagacc aactgtcgct tcaccaaaac ggcctaagag
     4021 gctcccataa aaatagtaag atgcacgaag actgttaatt ttaccataag gcattggaat
     4081 attttgaaca cctcttgggt caatctccaa tacatcgtca taacgcttaa cagtagctcc
     4141 catcaattcc atgatttcga caagactggc tacatccgaa atatctggaa cgcaatccaa
     4201 agtcaccaca tcatcagcca agataatagc tggaattaag gcaacgacac tatttttagc
     4261 accactaata gtgatttcac cttgcagtgg taatccacca ttgataacaa tttttctcat
     4321 tctaagtttt caatactctt tcaagatttc taataaggtc ttcaaaataa agtatatcat
     4381 aaatttatcc ttttttccat ccttttcaat tttattggat aaatcagagt tgacgagtta
     4441 gtaactgaat tactaatact caatgaaaat caaagatcaa actaggaaac tagccgcagg
     4501 ttgctcaaaa cactgttttg aggttgtaga tggaactgac gtagtcagta tcctacatat
     4561 acggcaaggc gatattgacg tgatttgaag agattttcga agagtataat ctttctcgaa
     4621 tcgctattgc ccctttttta tcccctaaaa ctgagtagga tctaagacta gatctcttat
     4681 ctaagtatcg gaatacggct gttcaactaa attttagcaa gaacttctcc ccttctctca
     4741 gttcacagaa gcgttttata cataccgtcc tatcagacaa tctattttaa agataaccgt
     4801 gactcaggat cacttctatc tgtcgttttc tctttatagt gatagacctc acgggataag
     4861 tcgtacatct ttcctcatgt atacaagata taaggacgtt aaaaggttac agtgaaaata
     4921 gaaaatctta gtacgaattc aattactctc gtgatttacg catataggtt acgactacct
     4981 ttttggactt tagagtttga gaccccctta tccgctatat acgccttact atcacgttcc
     5041 tgttcgtaaa gccacgattt cgctatccct tcctctgacg attcttattt ccagcgtcag
     5101 acttaaaacg gtctatcccc agaccgtttt aatccactac ctcacgatag tcaggcttgg
     5161 gaatcgctat ttgactcgcc gagaactttg acatcagata tactataaca aattgaaata
     5221 agaatcaaac aatttaattt tgaaattcaa atcaatttat aacaatattt tagaagatat
     5281 gctgtgctat tccagattca gtttgctata catgcctgtc gtaccacaaa atcccgtgtc
     5341 tgatgaggca cgggattttt tagcttcttt actgagatgg attttccttt ttagttcgtg
     5401 ccaatctcaa ggcacgattt ggattgagac gattaaatag ttcttccaat ttcttttcat
     5461 tccaaacgtc tgcggcggaa acaaaattac catccgcatc tcggaaagat atcggtttat
     5521 ctcccatacc agtctcctag tctacaaatt caaactcaaa tttaccaatg cggaccaaat
     5581 ccccatcttt agctccacgc gcacgaaggg cttcatcaac ccccatacca cgaagctgac
     5641 gggcaaattt catgacagat tcatcacgat caaagttggt catattaaag agtttcatga
     5701 gtttttcacc agaaagtacc catgtcgcat cgtcatcacg actaatttca aaggcttttt
     5761 cttcttcgtc aaatccatag taagcttctt cttccatatc ggactcgtcg tagagcaaaa
     5821 attctggtgt cttgtctaac aattcagctg tagcatctaa aagtgttacc agaccttgct
     5881 tggtcaatcc agaaattggg aagatagctg gtaactcttc aaattcatca taattttcag
     5941 ccaatttttt cttaaattct tcaagatttt cctgactctc aggcatatcc atcttattag
     6001 ctacaataat ctgtggacgc tccatgaggc gaagattgta agactccagc tctttattga
     6061 tagctaggta atcctcatat ggatcacggc cttcgctagc tgacatatca atgatgtgaa
     6121 ggataacacg tgtacgctcg atatgacgga ggaactgagt tcccaaacca acaccttgac
     6181 tagccccttc aatcaaacct ggcaagtcgg ctactgcaaa ggattcacct gattgggtgc
     6241 gaaccatacc taaatttggt acaatagtgg taaagtggta ggcaccaatt ttaggcttag
     6301 ctgaggtaat aacacttaaa agtgttgact tccctacaga tgggaatcct actaaaccga
     6361 catctgccaa gatttttagt tccaattgta actcacgttc ctgacctggt tctccatttt
     6421 cagagatttc cggtgcagga ttttttggtg tcgcgaaacg aatatttcca cgtccaccac
     6481 gaccaccgtg ggcaacgata aattcttgcc catgttcaat caaatctgtt aaaaccttgc
     6541 cagtctccgc atcacgaaca gtcgtacctt gtggtactag aactctaagg tcctcagcac
     6601 cacgaccatg catccctttg gtcatccctt tttcaccaga atcagccttg aaatgacgat
     6661 tgtagcggaa atccatcaag gtacgtagtc cttcgtctac aacgaagacc acattgcctc
     6721 cacgaccacc atcaccaccc caagggcctc cattagggac atatttttca cgacgaaagg
     6781 caaccatacc atcgccacca ttaccagcct tgaccttaat cttagctgta tctaaaaaca
     6841 tactcattat ttcttctcac tttaaaaaag ggctgggaaa tcccagtcac taaattttct
     6901 tgaatctatt ttatagatta ctgagggcac caattgcagt tgcaaaaatt cccaataaac
     6961 ttgctactag catgataatc acgataaaca aggttatttt ctcaaacata gtttttttac
     7021 gatttccatt atctccaaat gccatttttc tctccttcgt tacattctat tttctattat
     7081 cttagcatga attgagctag ttttcaatag tcagttgcta ctggtgcgat aatccataaa
     7141 ataatgtaag ctacaattcc agctccgtaa cagcaagtaa gaacacccca aatgactcga
     7201 acgatagtcg gatccatatc cagataatag gccaccccag cacaaacacc cgcaatcttt
     7261 ttatcacgac cgcttctcat taattgtttt tttcatagct gttcctcttt ctattcttca
     7321 tggtctttcc aatagtctct catactgatc aactgtgttt ttgaagcctt caacatgcgt
     7381 ctagaacctt ttacaggtac agcaaccacc tgttgcggaa gatacaaaac tgtcttaaag
     7441 atacgctgac tgaccgtatc atctttagcc aaatctttct ggaagttatt tgaaataata
     7501 gcatccagat aaaactcatg cactcgtttc ccaaagttct cagctgaaat ctcatacaat
     7561 ttctctgata aggtatgctc gttcatgtct ggtgttgcaa tcagggcttc caaaatagca
     7621 ccagccaaat catgttctcc atagtacaag gttccaaaca ttttatcact gatgaggttg
     7681 ttcaaataag gatttccgtg agcaatgaca ggtgttccac tggctaagct ttccaagtag
     7741 gtcaaacctt gcgtttcgct tgtcgatgcc gaaatgaaga aatccgccgc tttatagtaa
     7801 agagccgtct cactaggagc aatcatccct gtaaagatga ctgagtcttg aatctctagg
     7861 ttctgagctt gctctttgag gtcattcaga taagggccat ccccagctac taccagttta
     7921 accttgtctt cctctttcag aacatcagca aaggctgcta aaactgcttg aatatttttt
     7981 tcataagaga ttctcgaaag actaagcaac gtcttttcac catcttgaat ccctagttta
     8041 ctacgcagtt ctttcaaatt ttcctgcttg atttccggac gctcaaactt ggctaattca
     8101 atcccagtag gaatgacccg tttttcaacc ttgaccttat aatcagatag caagtcacgg
     8161 acaatctcac taggacaaat aaccccatcc acatcatgca ggaaacctct aaccagatac
     8221 ttgaccatac tcggccggat caacatcccc ttagcaatat aatggacata gtcttcatac
     8281 tgggtgtgat aggtatggat gactggaatt ttcaattcac gcgcaatcca aatccccaac
     8341 aggccaagag aaaattctgt ctgagtatgg ataatatcta gctgatactg tttagcaatt
     8401 tcaagtgcct tgctaaaacc tcggtaggca aagcgacgat ccttaaaagc aaagaaagga
     8461 acacttggaa tgcggataat ttgccaatct tcgtagcgat tgacatcctt atctgtcgtc
     8521 gtaaagataa aaacagcatg tccctgcttt tcaagttctg ttttcaaggt tcgaatactg
     8581 gtcgcaacac cagaaacctg aggaaaatag gtatctgtaa ataaaccaat tcgcatagat
     8641 tacctcactt tttactttct ccctaaagcg gcttgtttct cataaaagtc caaccagatt
     8701 tgtaacagat tctcttcaga atactctctg gaaatattct tagccttttc tttgagatct
     8761 tttaaggcag caggatttgc ttgatattcc aaaatagcct ctttcatctc ttctctaccc
     8821 gctgtcgccc gataatttcc ctccaaaatc accttataga gatctaaatc acgcaacata
     8881 ataggagcct cacaactcgc agcttctaaa atagtcatag gaaagagctc attgtaacta
     8941 ggcaacaaga aaagatccgc tagagcatac aattcgcgca tccgctctgg cgatacaatg
     9001 cctggaaaaa tcaaattttt agggggattt tccataattt tcttatagtg ttcataacca
     9061 tctgtcatac caccaaaaga gaagccacca gcccagataa aggtaatctg aggcaattcc
     9121 tcagccagac ggataaagtc atcaatccct ttacgtttct gaacttgccc agcacctact
     9181 acgataaact gattgtcact aagaccaaga tctgtgcgca gtctgactac ctcttcttgt
     9241 ggtagaggat gccatttttc cttgttgaca aagttaggaa tataggtcac tttttcacgt
     9301 ggaataccag ctgctaccaa atcctcaata aacataggat tgaccacaac caagtgctcc
     9361 atccggttgt aaaaagaaaa tacatagcgt ttcacaattc cctttaagaa aaatggaatt
     9421 ttcaaacttc cctcaagtgt agctggcaag aaatgcacat agccaatctt tctccctgag
     9481 cgtttctttt ggaaggttga taaataatag ggaaaatcaa tcgtatgaaa gtgagtcaca
     9541 tctgcctcga ttggaagatt ttctgtaaca atcaattggt ccttggcagc acggtgaaga
     9601 agacgaacta attcacggta agcacctgaa actccctgtc ctgctacttt ctcacttgaa
     9661 ctcaacatat tgatgcgtaa tttctttttc tccataacta ctattatatc attttctttg
     9721 aataaaatca gcaaaagaaa ggagagacta gaggaaaaga ggggaaattt cctcgctttt
     9781 ccaacagtct ctcacatgct tttatatgtt tacttaatgc ctagggcaat gcgggcatag
     9841 cgactcattt tttcaactgt ccaggctgga taccagacta atttaacctc agtatccgtt
     9901 acttctggaa cctctatcat agcatcataa atctggtctg tcaaaaggtc tgctaaggga
     9961 caacccatag ttgtcaaagt catgtcaatc tctgtttgcc ctgtgtcacc gtcaaaacga
    10021 atctcataga tcaaaccaag attgacaata tcgattccca actcagggtc gatgacttct
    10081 tccaaggctg ttaaaatccg tgttttgatg ttttcaattt gctcttctgt ataagccata
    10141 ttttcctcac tcttagtctt caataaaatc acgaagcggt ttgctacgac ttggttggcg
    10201 tagttttctc aaagcctttg cttcaatctg acggatacgc tcacgagtta cgttaaagac
    10261 tttccccaca tcttcaagtg tgcgcatttt tccatcatct agtccaaaac gtagacgcag
    10321 aacattttct tcacggtctg taagagtatc taagatttca tccaattgct cacgcaagac
    10381 gatacgagtc gtataatcca ctggattttc aatcacttca tcttcgataa agtctccaag
    10441 gtggctatcg tcctcttcac cgataggagt ttcaagagat actggttctt gggcaatctt
    10501 caagatttca cgaaccttat caggtgtcat atccattcgt tcagcaatct gttctggtgt
    10561 cggatcttgc cccaattctt gaaggagatt ccgctgttca cgaaccaatt tattgatagt
    10621 ttcaaccatg tgaactggga tacggatggt acgagcttgg tccgcaatag cacgagtgat
    10681 agcctgacga atccaccaag ttgcataagt tgaaaacttg aaccctttag aatagtcaaa
    10741 cttgtcaacc gccttcatca agcccatatt tccttcttga atcaagtcaa ggaactgcat
    10801 accacgaccg acatagcgtt tggcaatgga aacaaccaaa cgaagattgg cttccgcaag
    10861 acgttgtttg gcttcgatat caccagcttc aacagccagt gccaactctt tctcctcttc
    10921 attggtcaag agaggaacga cccctatttc tttcaagtac atacggacag ggtcattgac
    10981 cttagcagaa gttgacccaa tcaagtcctc atcgctgagt tctggttctt cttcattgct
    11041 gagaacacgc gcacttggat ttccttcgtt atctgtgata gaaatgcctg catcctgaat
    11101 ccgttgcaag agatcttcaa tcccatcagc gtccaaggta aaaggaataa ccagacttgc
    11161 attgatttca tcatctgttg ctgtcccttt ttgcttatga ttacggataa attctgctac
    11221 ctgtacgtca aatgttgtta cttctttttg ttttgttgcc attattactc cattcttctc
    11281 ttttgggaaa ttaaacgttc caattcttct agggctgtat ctgtatctcc tacatggcta
    11341 gcttcctgca ccttcttttt gattctcata ttgtcctgat tcaagagagc cttgtttcga
    11401 gtcatctcta cttcactaag ttcctgcggc gatatctcag caggcaaatc ctgagctaaa
    11461 acttggtacc aagctctttc aacttcctct gtctgctctg ctaaaacttc tggaggaaga
    11521 tttccatact ggccaagcaa gtcatataag acctgaaatt caggtgtagc aaatgcaaag
    11581 tcttctcgca aacggtaatc gttcaaaaca agaggggatt ccatcatccg atagagtaga
    11641 tgggcttctg ccctcataat agccgataac tgcttggtga caggcatggt gattggcgtc
    11701 ggtctggaaa ttctttccat gcgattctgc ctttgcacct gacgactctc attaacaatc
    11761 tgctcaatct gggtataatc aaaggacgcc agactgtcag ctaaaatatg aatatagctg
    11821 ttttgagcag cgatggactt ttcttgaaca atcaagggag ctattttttc aataaactca
    11881 atctgagcct gcagattttc actgttttca ggtttgtact gatgaatgta gaactcaatc
    11941 ggactaatac gagtttttgt taatagatag gccaagtctt ctggaccatt tttttgtaga
    12001 tactcatcag gatccaagtt atcaggcatg ctaacgattt gcacaggcat atcaccaatt
    12061 tcatccaatg ctttcaatgt cgcggcttgc ccagccttat ctccatcgta aacaagaacc
    12121 aatttcttgg ttaacctttt cagatgctca acatgctctc gactcaaggc cgttcccatc
    12181 gacgccacag cattttcgat tccagcccga taggctgcaa taacatccat gaatccttcc
    12241 atcaggtaaa tctcactagc ttttccagaa gatctttttg ccctatccat atgatataat
    12301 tcgtaacttt tgttaaaaat tgcagtcgat cggctgtttt tatacttaga agtttgtgaa
    12361 tccgtttttt gccagatacg acctgagaag gcaatgacct ttccttggtc atttgtcagg
    12421 ggaaacataa tgcgattgtg aaaggtgtct acaaattgat tggcatccga gagataaaac
    12481 aggcctgaat ccagtaaatc ctcttcacga tactgatcag acaaacgttg atagagatag
    12541 tttcgttctg gaggtgctaa accaatccaa aaatgtttaa gcacttcatc tgtcaaaccc
    12601 cgctgataaa ggtaatttct ggcctcttcg cccatagtcg ttgtcatgag aatagcatgg
    12661 taaaatttgg ctgcatcttc gtgcatatca taaagatctt ggtgaggtga ggctgacttt
    12721 tgctcactat aaagcggttt ttcaacctca attccaacac gctgacctaa gatttggact
    12781 gcctctataa agggaacccc ttggtactcc tctatgaact taaagacatc acctgagcga
    12841 ccacaaccga aacagtgata aaactgctta tcctctacaa cgttgaaaga aggtgttttt
    12901 tcaccatgaa aaggacagag ccctagatag ttccgtcctg ccttttgtaa agaaatcaca
    12961 tctcctatga cttccacaat gttggcattg tttttgattt cttcaatgac ttgtttgtca
    13021 accatacaca atacctccat gttatcatag tttactttat atagtatact ttatttcaga
    13081 aaaaaagtaa accatttcac tcattttcct tactttattc aaagagttga taataatcag
    13141 agattttcat ttttgctttt tcttcttggt ttaaatcttg gataatccgt ccttctttca
    13201 tgacaatcaa gcgattgcca tatttgagag catcttccat atgatgggta atcataaggg
    13261 ctgtcaattg atctttctta acaaattcat ctgtcaattc catcaaagca acactagtct
    13321 ttggatccag ggcagcagta tgctcgtcta acaagagtaa ttcaggtcgc ttcaaggttg
    13381 ccatcaagag actcaaagcc tgtctttgtc caccagataa gaactcaatc ggtgtattca
    13441 agtgtttctc aagaccgttt cccacttttt caatggtcgc ctgaaactta tccttatagc
    13501 tagccagacg tctcggaaat agtccacgct tttcaccacg aaacttggca atcaggagat
    13561 tctctgccac tgtcatacga ggagctgtcc ccatctttgg atcttggaag actcgagaca
    13621 gatacttagc gcgcttctct ggtgaaaact tggtaacatc ctcacctaaa atacggatag
    13681 ttccactggt tagtgatatg gttcctgcaa tagtgttaaa gagggttgat ttaccagcac
    13741 catttccacc caaaatcgtg ataaagtcct gttcaaaaat ttctaaggaa acatcattta
    13801 aaataatctt ttcttcatca aagccatttt taacgatttt ggttgcattt tttaattcta
    13861 caattgctgt catttgctta acttggctcc tttcaagatt gtttgcttaa atgttggaat
    13921 catgaggcag actgctaaaa tcaaggcact gtataaacga aggtaacttg tattaaagcc
    13981 aagtgcgata actgcccaca ctaaaaattg ataagcgata gaacctacaa cgatagtaac
    14041 caaacgctct gccaagctca aactcttgaa aataacttct ccaataatca aacttgcaag
    14101 ccccacaacg ataaccccga tccctcgaga cacatcggca taaccttctt gctgagcaat
    14161 gagggcacct gcaagggcaa tcacaccatt tgataagacc aagcccatga gctccatgcg
    14221 tccagtatga atcccgaaac ttctagccat atcaggatta tcccctgtag caatataggc
    14281 ttgtccgagt ttagtgtcca agaaaaagag catgagagca ataacaatac tcacaaagat
    14341 gagacctgtc aagagttgat tcaaatccga atcaaaaggc aaaacatcct gaatttgctt
    14401 ggttccaagc aggcctaaat tcgcacgtcc cataatcaag agcatgattg agtgacaaga
    14461 agtcatcacc aaaatccctg agagcaaggt tgggatcttc ccttttgtat aaagaaggcc
    14521 tgctgccatt ccagccaaac aacctgctcc tacagcaaca agtgtcgcta aaaatgggtt
    14581 cacgcctttg gttatcaaag tgacagcaac agctccccca agagggaagg aaccttctgt
    14641 cgtcatatct ggaaagttta aaatcctaaa tgtcataaag attcccagac ctagaatagc
    14701 ccagacaaat ccttgagaaa taatggaaac aatcatattt tatttaatcc tttctatatt
    14761 catcttttta aaaaatggga agagtctcct cctccctacc ttatttattc gatgacttgt
    14821 cctgcttctt tgagaacaga ctcaggaata gtaataccta gttcttgtgc tattttttta
    14881 ttgatgactg acttaccagt tgaaaagaca ttgactgggg tatcggctgg ttttgcacct
    14941 ttcaagactt gcacaatcat tttacctgtt gccacaccaa ggtcatgttg gtcaattaca
    15001 actgatgcca aaccacctac ttctaccata gctgtcgcac tgggataaat tggtttctta
    15061 gaactttgat tgctagagac aaccgttgga aatcctgatg caatggtgtt atcaattgga
    15121 acccaaatag catctacctt gctagtcata acagtgacag ttgaggcaat ttcatttgtt
    15181 gaaggaactg caaatgtttc cactgtcaga cctgcttttt cagcataagc cttaaattct
    15241 tcgacctgtg tttttgaatt gtcttcgcta cttgagtaaa gagctccgat tgttttcaca
    15301 ttcggtgtca gagccttgat gagttcaact tgttgttgag ctggattgtg gtcagatacc
    15361 cctgtaacgt tgccacctgg ttttttcaaa tctttaacca agttagcacc aattgggtct
    15421 gtaatagcgg ccatgataac cggtaggtct tttgttgcac tagccaaccc ttgggctgct
    15481 ggtgttgcga taccaaccac aaggtcattc ccatttgcaa ccaattgttt actcattgtc
    15541 gcaaccttac tttggtcacc ttctgagttc ataaaatcaa ttttaacttg atcatcttta
    15601 tatccttctt ctgcaagtcc atcttggatc cctttataaa tcaaatcaag ggatggatgg
    15661 ctcacaaatt gaagcacacc aatcttggtt attttcttct catccttatt attctgaact
    15721 tctgatttat tcattgaaga ataaatcaag cttcctgcta ctaagactgc taatgcagca
    15781 ataattccaa ttaaacgttt atttttcatt ctgtttctcc tttttatttc ctttaacata
    15841 tttcacttat ctaaacaagc gacgccatcg ttttctttcc atactaacct ccatcaaaaa
    15901 aatcctcaca caaaaaactt gtgtgaggac gtcgatgcgc ggtaccacct caattatagg
    15961 gaatttccct atcgctcagt ctcgcaataa cgagatgcac tgtaaggtgt gcttaccgaa
    16021 tttttataat ttcaaattct aaatagcatt cagcccaatt ttcatcattg ccacttatct
    16081 gttttcagct accacagact ctctaaaaag tttgtatgat tacttttctg aatggttaaa
    16141 ttatatcatt tttaaactac ttgtcaatag tctattagaa tttttttgat attcactttt
    16201 agcattcact cttgaaaatt atcaacctga attacgcaat cctgtcgcaa ttccgttgat
    16261 ggtgatatga atcaatcgtt cttgatcact ggacaattct ccacgacgtt ggcgtttaat
    16321 caactctaac tgaatatagt tgagaatatt aaagtaaggc atacggtaat ccagactagc
    16381 ttttagatat ggattgtcag ctaagagttc gtcatgtcct tcaatagcca agataacgtt
    16441 cttagtaact tgccattcat ttaaaatagt ctcatagatg gccttaactt gctcgtcttc
    16501 acaaagttta gcatattcaa aagcaatatt catatttgat tttgacaaaa ccatatcaac
    16561 atttgaaaga agcgattgga agaaaggcca attttggtac atatctcgta agatagcaat
    16621 attctctgga tttttattga taaattcctt gaagcttgaa ccaaccccgt accatccagg
    16681 gaacataaca cgactctgtg accatgagaa tacccaaggg atggcacgca aaccaccgat
    16741 ttcagtaata gtcttacgag cggctggacg agaaccaata ttaaaacttg aaatagcctt
    16801 gattggactt gactcgaaga aataatcata gaaatgctca ttaccaaaga ccaaatcacg
    16861 gtagatatcg taactacggt ccactacttg atccataatg gcttcataac gatttggggt
    16921 attggtatcg ctcttcttct gagtaatcat acggttaata gctgccgata ctagcatttc
    16981 aaggttatag taagcggcgt ctttgttacc gtatttattc ccaattactt caccctgctc
    17041 cgtcaagcgg atacgatcct tgatagactt gagcggttga gatgtaatgg cttcataggt
    17101 tggcccacca ccacgaccga cagtaccacc acgaccatgg aagaaggtaa ccttaacgcc
    17161 aaattcatct ccaatagcag tcaattgttg ttgagccttg tagagggtcc aacatgatga
    17221 caagtaaccg ccatctttat tactgtcaga gtagccaagc atgatttctt ggtagttatt
    17281 tcgtgagtca atccattttt tggcaaggct aagagaaaga tattttctca ttgtttcctc
    17341 tgaatgatcc aagtcttcaa ttgtttcaaa aaggggaaca atctgaacac gcgccctttc
    17401 cgtatccacc agtcctactt cttttaacag aatagctaat tctagcatat cagaaaggct
    17461 ggttgcatgt gaaatgatgg tctgacggat gacatcatct cccaacttat ctttcaaaac
    17521 acgagccgtc ttaaaaatag ctaattcttt tgctaataat tctgattttt ctgcgtgagt
    17581 cgcagaaaga attcggggat cttcttctaa ttctttcaag agaaggtcac acttttcttc
    17641 ttcgctcaac tcgctataac gagaatgaat tcctgctgat ttcaagagtt ctgccacaca
    17701 ggcttcatag acgctagagt cttgtcgcat atcaattgat gctaagtaaa aaccaaatat
    17761 ctctactgcc tgcaataatt ccacaaaatc acctgaaatc aaggactcgc ccttattttc
    17821 tagtagagaa tctcgaatgg caatcaaatc cttgtagaaa tcattggcgg tttcataacg
    17881 agtcccaact tcttcatcct caatcagata ggttttagtt gcctgaattt ttgattgaat
    17941 atcaaacaag gcacgacggt aaagctcttt ttcgcggtaa atcgagttat ccttggattg
    18001 acgagccatt tctctgactt gcttgctgac gttgacaatg ctagttgaaa gagaaaattc
    18061 acgataaagt tggtaaatct ttttatcata gtagttcatg atgacttcac actgagtgag
    18121 tgcagactgc ttcaaggtct ttgctgtaac aaatggattt ccatcacggt caccacctat
    18181 ccacataccc atggtgattg gtttagcctg ttttaaattc agaccatgcg cttgcgctaa
    18241 gcgcttatac tccgtcgtca aatgaggtac agctttcaaa aaggagctgt tataatattc
    18301 catagcattc gtgatttcgt tagtcacttt taattttttc tcacgaatca tgtctgtctg
    18361 catgataatt tcgatgtaac gacgcaaatc attgtaccat ttatctttat tgatcaaccc
    18421 caacttaaca tcacggtatt tacgcaaaag actatgaata tgatttgtta aatccaacat
    18481 acttttgcgt tgcacttgtg ttggatgggc tgtcaaaaca gggacaacat tcaagtgttc
    18541 taggatctca acggcatttt ccttttctgc taccaattta atcgttgtag ataatttacc
    18601 taaatagtcc tgatcaatat tattttgatg attgatttca taagctaaat ccacatcctc
    18661 tgaaatatta atcaaaagag gcaagataga gaaatagcgt gaaatataga ccatttcatc
    18721 atttgataag ctagtcacta gacggtttag accttgataa tcttcctgcg ttgataattc
    18781 tttcaactgt attatttttt caaaggtctc tggggcaagc atatttttag taatatcttc
    18841 cagtaattct gttagaatca agacttcttc ttgcacaaca cttttattac tataattttc
    18901 taatttttga agagacataa actatccttt ctttatccta cttcaacaga aggttcattg
    18961 gttgattttc caattctcgg tacaatttag cgcgtttttc actggcatca atatttaaga
    19021 caaaggctac tgccactgat aagactagaa gactatttcc accctgggat aagaagggga
    19081 aagtcactcc tgtagatgga atcaagcccg aaatccctcc gatattgaca aatacctgaa
    19141 ccaacatcat ccctccgaca ccgagtgcaa ccatggcatt gaaaggattc tccgctcgga
    19201 taccgaccaa gataatccgc aaaatcatga aaaacaagag agctaaaata agactggcac
    19261 caacaaagcc aaattcttca atcacgatag aaaagacaaa gtctgtatga gcttctggca
    19321 aataacctcg tttttcaatc gagtttccaa gacctagacc aaaccaaccg ccattgacca
    19381 tggcaaaata agaattagct aactggtgac ctgcatcagc acgatcggca aaaggattaa
    19441 aaaaggcact aaagcgcttg gctacatagc cgaatactgg aatttttgaa aaggtctcaa
    19501 caccgattag gctgatagtg gtcaagacaa agacagaagc ggcagatacg agcgccagaa
    19561 tggttgaaaa ccagcgataa gcgattccac taactgtata cataatcaag gaaaccaaga
    19621 ctaaaatagt cgcatttcct aaatcaggga aaattcccaa acttccaatc agaactagga
    19681 gaacgaatcg ccaatcatta aaagcacggg gaagccattg attttgagtc aaaacttgaa
    19741 aatcataagt agctatttct tcttgctgtt tggagaatcg gtgagctaaa taccaaataa
    19801 taatgatttt taagtactca gctggctgaa tagttactcc tgcaaccgaa atccaaccgt
    19861 atgccccgtt tacggaaaga ccaataaaac gagccaagaa caatagaagc atttctatta
    19921 atataactaa aatgattagt cgctcatttc tcaaaaaatc tagtctcaat ttataaatta
    19981 aggcaatcag tatcaaacta acaatccaaa agattccttg gtttcgaacc aactgcaagg
    20041 cactcttgcc ttcttcaatt aaaatagcac tggtggtcga atagaccaca atcaagccca
    20101 aaatagataa aagcaagtag ggaatcaaga tggaataatt taataagtgc ctcttactaa
    20161 tcttcatagc atcaccactc tactaggata cagacaaatc tgttccaaat tccgttttat
    20221 tttctagttt tgattgctat tataccattt tttcagaaag aaaaaaactc ttaccttata
    20281 atccttcgaa ttttactgtt tttcataatt agagcagaat ttgaaatcgt aaaaccattt
    20341 tgaacaagag ttacttcaac ccattgactc cgacggatta agttgctttc gtgaatgcca
    20401 aaatcagccg aaatttgttc ataagtgcgc tattctcgca tgtattgaat agttaccata
    20461 aggagatcgt ctaggcttaa tttggttttt cgtccacctt ttgcgcgttt acgttgataa
    20521 gctgttttta acacagctaa catctcttca aaagtcgtgc gctgaacacc tacaaggatc
    20581 ttgaaacggc tatcgctcaa ttgtttactt gcttcatcat ccatagtttt attgtattgt
    20641 atttttgttt cgcaggaagt ctattattcc tttcgttcca aggtttttac gcttttagca
    20701 acaagcttac acactgagcg tttcggactt accatatcat ttcgttggag attttatcat
    20761 caatttttag attaaaaaag atttcccaat cttcacaaac ttctgtagca ggaattgtat
    20821 gaatctttct aagtatcttt cctgcttcta caccatatgt gtattgttgg ttttatgaat
    20881 aagttaaaat gctatctatt gcatctcttc cgtctatcca ttcgtgtaaa gaatgtactt
    20941 cgtcatcgca gagttcaatg ctaattggtt tacacatcgg aactccaaga gaagctactt
    21001 tctccatcgt atcaaattca atttttttat aatctaactt cgacttatca gaaacacgca
    21061 agaaatatgt ttactgattt tgaactgtca cacaatattt tttatcatct gaccagcctt
    21121 tatttatggc tatcttacta ctaaaatcca tcaagcacac tccgattcac tttacaacac
    21181 tttttgcagt tttcactagt aacctatcca gttcgtctac acttttattt cctagatcca
    21241 tttttacatt atgaaagtta gtcaattttc tctatgatgt ttccaagttt atccaataca
    21301 agacaagaat gatcatttag tggaattatg ggaacattaa cgagttcttc agctctatcc
    21361 ttatttgctt tatcattcca ggaatcataa tggacactaa ttaaaaactg actaaaaagt
    21421 cctaatccat tttttatctt tatctgataa tctgaattaa cattaggtga gacatagact
    21481 ttttctccta atagtagggc tcctgcagaa aatcctataa tttttgcctc tttattaagc
    21541 atatgatcga tataactttt gaactcctga ttaacataag tagcaatata tttttccgta
    21601 tttccaccac cgatgataat tatgtcagca tctagatagc tatcaagatc aatctgctca
    21661 gtgtccagga gcaagtaatc aatgtttaga ttaggaaatt gactttgaaa aacttccgtg
    21721 tactttttca tgtacggttc ccaattttct cgaaaaactg taaaaatgac aattctttcg
    21781 atcttccttg atgacacaat tttattaaca atcgtatagt tctttatcgg cggattccca
    21841 cccatcaaaa aaatttgttc tttcaagtta tcacactttc taaagataca taaagtttaa
    21901 acaagtttat tcacgtttcg aaattataat ttttttaaaa catatcattt tattgactgg
    21961 ctaagatcga accagcaaca ctacacactc cacgtgtgtt gtctgttcct tgagaataca
    22021 attttttatc ctcgtcactg ttttgaggac acaatttatc tgtttctagt ttagcatttt
    22081 tacgtttact tttaaattgt ttaccatcct tgttttgaat ttcacctgtt ttgaatatta
    22141 tggttaacat tgcaggatca atttctccgt tgctattaac tccacctaca ataattttct
    22201 caacaatact ttcaaaaact gcacgatcaa actccgtaag cattttttgc gaagatagca
    22261 agtgcttaaa ctcagttagt cttttcttta catcgatttc tgattttaat gttgtttcaa
    22321 tatttacctt ctcttctgct agaaactctt tttctgagga aatttcattg tacttttcat
    22381 tgtatatgga atcgctaact tttccttcga gccttagatt tacaagattc tcctcttttt
    22441 ttagtaatat tcgaagtttg tttgtaatcc tttttagttc cttgttaagg ctattgtcat
    22501 tcaattcaga ttctatcgtt tcaagtaagt ctgtcattaa attttcattt gaatgataga
    22561 cttgtctgta agcttccagg aaagccccct caatggcgat ctcttctaat cctttactat
    22621 gcttacaaaa tttctttcct ttctttatcg atgtaacaca gtgccacaca actttgcgat
    22681 aatctgaacg gcagtgccaa cttcttctag ataatattga accacaaaaa ccacattcca
    22741 acatgctact aaaagcatac atttttgaat agcgttcacg cttcccattt acattcgcag
    22801 ctgtcttctt atttcctgct cgacgcaatc taatctcctg agctttttca aaatcttctt
    22861 tagatattat tggttcatga ttatccttga tatagtactt atcttcttct ccaaaattac
    22921 tcaaccgtct cttgcttatt gggtcaactg taaaagtttt tcccattaga atatcacctt
    22981 tatatttttc attctttatt attcctagaa ctgttgtatc attccagtgt tctaaacctc
    23041 ttggcgattt gtaaccaagt tcatcaagtt cccttgcaat tacttttcct ccaatacctt
    23101 ctagatacct ttcaaaaata taacgaacaa ttttggcttc ttttttatta attgaaatct
    23161 gcttggtttc tacatcataa tcatacccta agcacccttg aaaaccaacc aattcaccac
    23221 gttgcatctt catttttaat ccttttttca catgggcaga agtattctct acttcttgct
    23281 gtgcaacgga gcttagaata gttagaagca attctccatc cattgttagg gtatctatgt
    23341 tttcttcctc aaaatatact ccaatttgca tatcctttaa cattctgaca tacttcaaag
    23401 tatctagggt attccttgca aatctagcaa ttgcttttgt gacaatataa tctatctctc
    23461 catttgcaca atcattgatt aatcgttgaa aatcttgtct ctttcctact tgtgttcctg
    23521 aaataccttc atctgcataa atatctgcca gctcccaatc tgaacgctga gaaatatatt
    23581 ctttgtagtg tcttacttga gaatcataac tgtttttctg atcctcacta tcggaactaa
    23641 ctctgcaata agcagcaacc ctctttaagt gtctttctac attgtcgcct cttcgacgaa
    23701 ctaaagaatc agcttttatt atttcaacat tatttttttt catactgaaa ttcctccttt
    23761 tgattctata ttaccgcatt caaatcaaaa agtcagctat tttgtgtact taatacgcag
    23821 tttgtttcta atcttgtcat actcattttt agataacata tttcttgagt ataaaaagtt
    23881 aagcattgat agttgcatag tatactttat tactgattgt tccaaacttt ttcctccttg
    23941 taacatgtat aatttcctcc gtgggtatga ctggttaaat cattcatggg catttcaccc
    24001 gctgtccttt ttcgctggca gcctgaacgt tcagaagtat cattatcctt atttgtagtc
    24061 atggcagata gagaaccact ctattttata gctaataatt atcgctccta tcacggcgta
    24121 tcaagctaaa gtgctcgaca aataagaaag tcccacctcg gtttattcag ttttcaaagg
    24181 gcttaggatt tattgacaac taaacttatc catctctaaa atataatctg tagttacctg
    24241 atataattta gctaattgtt tcaaaaatga tgtaggaata tcttgcttgc cactttctat
    24301 tctagaataa gcagactgtg aacaatgaag atactgtgca atttgacact gggacaaatc
    24361 tttgtcttct cttaaattct ttaatctgat atacattaat aatcctctta ctaatattgt
    24421 aatttgaaga ttatcaaatt tggaatttta tgcaaaatat gcataaaata atttataaga
    24481 ttttagaaat agttggtata acagtaagta agctataagt tactaaaaaa agattttgga
    24541 ataaactttt tcatagcgat aaaagcaccg tacaagctag gaaaataata agtaatcgcc
    24601 caatctgacc ttctccagaa cttgattatt cgtcaatcac tacagttgac aaacatacta
    24661 agattagtag tgaggaaatc tccaacggga gagagtactc attacttttt ctttgtgtta
    24721 aaatagtggt gtcttgttaa gtcatagagc tctctatggt gctagacgtc gcttgacaaa
    24781 ctggcaagaa acctgtttta ggaagaattt tatcaaagta tgtgggatac tagacgtcga
    24841 gtattggaaa taaaatcact aaaacaagga gtcattcaag acaaaggggt aaacatgatg
    24901 cggacagttt tcagaatgga tgtgagtaag gcaagctcag aagtcgctat tcttgtgaat
    24961 ggtgaaaagg ttcatggcta taccatgccc aatgatgcca tcggatttag tcgtcttcta
    25021 gaggatttga aataggtaaa tacacctgag attatcttcg aggcacaggg gtctattctc
    25081 gtcttcaggc ctttctggag gacaatagct atgcttatat acggctaaat cctttaaaac
    25141 taagaagcaa ctagacagtt tgcgagtccg taaaaccaat cagattgacg ctgaaaagct
    25201 agcttcgtca caattcatcc ttaaccgcaa accaacttat gttcaagaag aagtctatca
    25261 aaatttgcgt gacctcagtc gattctatca gaatctgaca gaagacatcg ttaggactaa
    25321 gaatagcctg cacaaggtgc ttcaaattgc ctttccagaa ataaagaacc ttctctctac
    25381 tcctacaggg gaacaatatt ggaacctcgt gaccatcttt ccaaccaagc attggaggct
    25441 gaaattatca gtagttgagc taaaagaagc catcgtaatt caacttctaa acggatttct
    25501 gagaacagag ttggacgatt ggctgaaaag ttgagcgagc tggccgaaca gtcctatctt
    25561 gccatttcaa aaacctctcc catgacagaa gaggttaagt atcatgcaca ggaactgttg
    25621 agactgacaa accgcaagga tcaggactta gcacaaatga ttgaattggc tgaaccatta
    25681 cctgaatacg agattctgct ctctattcct ggtatcgcag aaacaacagc tacaagcatt
    25741 attggcgaat tggagacatt cgtcgctttc agtctgccaa ccaaatcaat gcctttatca
    25801 gtattgacct cagacactat gaatctggca atttcctagc tcaagaacat atcaccaagc
    25861 gtggaaatcc ttacgcgaga aaaattctct ataagtgcgt ccacaatatt gcttcagcta
    25921 gtcataccaa tccttgtcat atcgcggact tttatgagaa acgaaaaaga caatcgcaga
    25981 cgacttcaac caagccatat acgattgtct ctatacatcg cctcatccgg acaatgtatt
    26041 acctcataac gcataacaaa ctttacgact acactttaac ccaaagtcat taaagtcatc
    26101 tatgtcctat cattgtaaca ccttattttt taataccaga taagtgtctt ttaagtgtgc
    26161 ccaaatttca aaaaacagct cgcaattatc ttctaaacat tcctttgata ctcattcaga
    26221 aaaccttttg agctagaata tcgtatgtcc cttaacaaat ggtatgtata aaagagctaa
    26281 aaaaccactc atgatatgaa cgagtggtta tgactgaaat attacatacc tttgtatcat
    26341 ttttgcacaa tggtcaaatt tcttgtttga aaaactacag taagcctaat caaagctctc
    26401 aatgtatcat taaaacttcc ttccaaagaa taggaagttc tatcaaaatt cttaattaga
    26461 ttttacttct tctaagaccc tgcgctctca tatgcatcca aacctttgtt ccataatttt
    26521 aatgataagg taaaaaatat taatgagata aggatcaatc caccaatatt gaacaatcca
    26581 tccttgtctt tcaagaaata gctagctggg taataggctg taaaagcaaa aggaatgata
    26641 aaactaatca accaacgtaa aaacgaatgg taaatcgcaa tcgggtattt tgcaaaatca
    26701 ttaaacatgt aaaaaatata aattattgcc ccagattgtt tagtccaaaa agcaatacta
    26761 gctgttacaa tttttaaaga ggtataaatt aaggttgcaa agggaatact gattaaaaag
    26821 agaaaaacct ttgcccaagt ccaagtaaga ctagttattg tcattaacag caataagacg
    26881 cctactaaca attctccaag agcatcaatt tgaaacgttt ctactaaaat atgaaacaaa
    26941 gggctaatgg gtctagtcaa atacttatca aattctcctt tacgaattaa atgttgtcct
    27001 aaagctcaca gattatcaaa aaagagatgg tcaattccct taggaatgag agaaaaacca
    27061 taaataaaag caacctgatg aaaactccag ccatcaagta agggaatatg ttgaaacaaa
    27121 atatttagaa acagcatgtt taacccttgt gtcaaaaaga cacccacaac accaactaaa
    27181 aaatcagcct tatactccat aatctgttta agatattgtc ggataaaaat caggtgcatg
    27241 cgttgatatt tcttcattct aacctccttg aatagttata taattctgta cgcacttcca
    27301 aatcagttgg gataaggcaa tcataataaa cagccagaat aattgtagcg agagcgcctg
    27361 aatcatttga ctcatgctat acttttctat aataaccatc accggggtat agattaaaga
    27421 agaaaatggc aaaaaagata atagttcggc aataattttt ggaaaaaatg tcagaggaac
    27481 caaacttcca gataaaaagg caactaaaga atttttcaaa agatttgatc cccataagtt
    27541 tttaaacaca aaagctgaaa aaccaaagca aatattgaaa aaaaaaatta atcaaaaaag
    27601 ctaagattaa gctaagaagg taaactgtgg ttattaaaac aatttgtaag aaggactcac
    27661 ctgataagag ctttagacct gcaatcagaa ttacaaatgg tagaccaaca ctaacaaaaa
    27721 ctagccatct agacccaatt tctgtgaaaa gataagacat tgcaaaatga actggacgaa
    27781 gcagtcgcat aataatagag ccatccttta cttcccatcc aatcataaaa gaactatctg
    27841 attttgtcag tagattcgtc acaaaactca tgatgatata taaggtcata tcagataaag
    27901 taaaaccttg aatgagagac tggtgagatg aatcaaacac agctttccac aagtaaaatg
    27961 ctacaaaggc ccccatcaca tccccaatgc gataaagaaa aaaattgaca cgatacgtga
    28021 ttaattcttg gattccagcg ctaacaaaag gcttatagcg tttccataat ttagtcatcc
    28081 taaagctcct ttcgatagaa gcgacgaata atatcttcaa tattcgcatc cgtcatcttt
    28141 aaatcacgga tcgtaaaatc agacaaagtt tgttgaataa tgtcagccgt ttgatactgc
    28201 gagctgtcgt actgaatatc aagtgacaat tcctgtctcg tcacatagat atcagaaagt
    28261 ccttcaaaat gagagacaat ataatcctgc ccaggatgta gttcaaaaga gagagtcttc
    28321 atcttcccga aagtcttttt cagttgattc acagttccat caaagatttc tcggccctta
    28381 tcaatcataa aaatacgatc acataactgt tcaatatcac ctaaatcgtg ggtcgttaaa
    28441 agtatggtcg tctcttcttc ttgattaatc tgtgtaatgg cacgtcgaat attatccttg
    28501 accgaaacat ctaaaccaat agtaggctca tctaggaaaa gaactttcgg attatgcaat
    28561 aaggaggccg caatatccgc cctcatacgt tgacctagag atagagttct gacaggatct
    28621 tgaataaatt ccttcaaatc taaaacttca tttagaaaat ccatgcgttt ttgaaagacc
    28681 gcatcaggaa catcataaat ttcctttaaa accgagtaag tctcctgcaa agccaaatcc
    28741 caccaaagtt gagttcgctg cccaaaaact acaccaatat ctttaacata gccttgacgg
    28801 ttctcttgag gaatctttcc attgatacga caaaaacctg atgttggttt caaaatcccc
    28861 gtcaacatct tgatagttgt tgatttcccc gctccatttg cgccaataaa gcctaaaatt
    28921 tgtcctttgg gcacctcaaa tgataaatct ttaacagctt caaagacttg tctcttggga
    28981 tgaaaaaaag agcgaaaagc tccctttaag ccaggttcct ttattgtttt cacaaaattt
    29041 ttctgaagat gctctactgt tatcattttt ataaatcact cctttcgttt cactcaagtt
    29101 ataatatcaa caaaaattgt agcatactac agtaaagtta agaaaattta ccatcattac
    29161 aaaccatatg aaaaaagcta ctaaaactat gccatcttgt attttatctg taagtaagct
    29221 aaattactca agtacaaaga attatgacga agaacatata aatttataat tggataaact
    29281 atagatttca gcaaacgaag ttatcccaat ataaaaatac tttaataact gaagatattg
    29341 acaggaagat attaaattcc tcattactat cctttactat gcagtataat tttaatatca
    29401 tttacctact tccaagatgc tgaaaaatac taagtcacac tattatgatg ttattatttc
    29461 catttttatt ttaacagatg agtcaattct ttcaactacc ccctccctta taactatatt
    29521 catgaagtat tcttgataat aaacctcatt taacttctca aagtagtcag cttctgcaac
    29581 tgctattatc tcataacaga ttgatttggt ttcaataaat ggaagctaga agccttgtca
    29641 gctaccctgc acagttggtg ttttttcatt tttctcttca aaaaaattgg tcggaagtta
    29701 taataaaaag gtgatgtgtt tgtggtgagt tgaattaaga gacaaactca ctttgtctta
    29761 acttttaaat tgcctaacaa aaatacggag attattctct aagctttaac tgcaacatta
    29821 tgtctctaca accaacgata agtccagaaa tctacccaaa taaccaaaca acctacattt
    29881 gttgaacttt gatgacaagt aggaaatttt acatttgata aacactattt tgtacgcatt
    29941 ttgcacataa tttaacgtgc tttccatcaa tttagttaag gacttacata gaaaacaatc
    30001 cgtttttgct tatgttaaat tagtagaatt agacaaaaac aaaaccgccg ttcgcactgt
    30061 tatatattca tttttagtac ttactattct aaaaaagata tctatctttc aattcctcaa
    30121 tttcttgact acttattcct agttctgtat taatatatct aagtattcct ccatattctt
    30181 tatcaaggac attcaatact cgattaatat attcttcttt tgctgaactg agtgaaagta
    30241 aattatgcat caatattaca ttcccactat ggttatttac atattcaata ttttcttttc
    30301 tcacatttat taaatacttg ttagatagta agtaatcatg aaaaatatcg ttcatatcta
    30361 ctcccaatat ataaagcaag aacaagctag ctattcctgt tcgatccttc cccattgaac
    30421 aatgaaacaa aagagattca tcttttggat gacttagtaa taatttaaag aatttcttgt
    30481 aaccaagttt actctgtttt tgattgatca tttgatcata agtttttatc atatgttgaa
    30541 aacctgcatc tgatttgtta aaaaattcta ttgggaattc tgtcaactct gaatcatcat
    30601 tatagaatat tggaattact atatttttta tattttttat attttttata tctggatctg
    30661 gagctttttt tatttcattc gctgatcgaa agtcaatgac ttttgttatt ccatagctct
    30721 gtaacaaatc gacatcaatt ttagagattc caaatagttt acttgaacgg aataatgttt
    30781 taggttttat tttttgtcct gtttgagtga ggtggtttcc aagatctcta aaattatatt
    30841 cttttagtaa agttagatta ttcaatgctt ttctccataa tatgctcaaa aaaccatctt
    30901 tattttattc aacatctccg gttgttaatt taaattaaaa aaggctactt tcgagtattt
    30961 ttgaattatc tactggatgt ttgttgcaat tctaaaactt cctcgtcaat ttttttcaaa
    31021 tcaatcctat caaacaacat tgatacatct gatagcttgt taggaaggtt tgaaatataa
    31081 ttccaagtat ttagctttgt tttaaacata tcctcaatct ttttaccaga aaaaggaatg
    31141 aatggattta acatttgtcc taaattaagt ataatgatta cacaagtagc taagacttct
    31201 ttacattttt caatatcgga ctctcgcaat gcccacggtt tcatatcatc atagaattta
    31261 ttagccgatc taatatattc aaaaatttct tctaatgcct gtttcatatg cccgctctca
    31321 actaaattac ctactgttgt atataattct ttcaaattat ataaaatttc tccttcgaga
    31381 tatttagtgg gtatttcaga ttcaaaatac ttttcaataa actttagagt cctattgata
    31441 aaattaccgt acgatcctaa taattctgag ttatgactat aaataaattc tctccaagaa
    31501 aaatttgcat ctttcatctc aggagcattt attgttagga agtatcggat tgaatcagca
    31561 tcatattttt ttatgatatc gttaagccat atagcccaat tattacttgt tgatattttt
    31621 ttgttttcta acgttaaata ttcactagaa ataatatact ctggaagagg ctctatttct
    31681 aaacctgaga gtattgccgg ccaaataata gtatgaaatg ggatgttatc ttttccatga
    31741 acataatatg actttgtccg attgttccaa aaatcagtaa tattattttg aagtttttgc
    31801 gcccaatcaa cacttgctgt gtagtaacct gctaccgctt caaaccagac atatattttt
    31861 ttatctctaa aaccatcaat gggaactgga atcccatttg gtagatcacg agtaacagct
    31921 cgatcaggta aaccttcccg taaatacctt ttagttagat ttattgcatt ttttcgccat
    31981 ctcactgttt cttcagcatc atttaagtaa gtctctaaca aattttgaaa ctcactaaaa
    32041 acataataaa agtgttctgt ctcacgaact tctggttcat tggaacaaat agaacatctt
    32101 ttatcaacta aatctatagg atctaaaatt gctgagcaat tatcacattg atctcctctt
    32161 gaatgggttc cacaattcgg gcattttcct tcaacgaacc tatcaggtaa gaattgatta
    32221 tcaaatgtac aatagagttg tttaattttt tttgtataca aaaatttctt ctcgtataat
    32281 tgcaaaaata attcttgtac tatctcatga tgtagtggag aatctgttcg cgagtacaag
    32341 tcatatgtaa aacctaattt ttcaaaagtt tctttaaatt ccttatgata aaaatcagca
    32401 atttctttca cagacttatt ttctttttta gctctgatag aaataggggt tccattacaa
    32461 tcacttccag aaacatataa aacttcctct cccttctgac gatagtatct tgcaagaata
    32521 tcccccggta aaagcgctgc cgcgtgacca atatgtaacg aaccgtttgc atatggccat
    32581 gctcctccaa taaaaattga catattgtat ttctccttaa attctttatt tttattataa
    32641 cattatttaa atgcaatatc ttttcaatca ttactttttt tgaaaatatt catttatttt
    32701 atttacaaac ctttgcaata acacaaaaaa attagatacg tgtaatccat ctcccattcc
    32761 atgattaatt tgtaaattca ctgtacaaaa atatctttgg ttctcttgaa taacttttcc
    32821 ccacgttatt cgaggaactg tatcaatttt tgaaagattc ataggagtgc ttacatgtaa
    32881 aaaatcaatc catggaacac aagaaagata agcaatgtta ttcttgtcaa tatttggttt
    32941 ttgcccttct tctgccttct gtttatttat gttgaacgca gaaacaaatt caattaaatt
    33001 atctcccatc gtaaatgaag aaaaattaag cttatcttcc gatgtaaggg tagtgaaaga
    33061 acaacctctt tgattgtatt gccagacaat ctttccgtcg gtatccatta gtaattctgg
    33121 aatagaattt attgcactca taacacacca cgatattatg gcataaagtg atatcgaatg
    33181 ttttttatga aaattgatag cctgcgttac ttctattcgt gaactcatag ataaataagg
    33241 aacatccatt ttattgaaaa agtcaaattc ttcattcctt ttccactctg atataggaaa
    33301 tgtcattcgt ataaattccc ccttaccact ttcacttcac tctcttctga gaacaagcca
    33361 ttcttataaa gtagtcttaa gatttcatct ccagatagag taaaaatttg taattcatct
    33421 aaatattgtt tagcaatatt agtaccgaat ttaatttttg aatacggtgc aggaaaaatc
    33481 cctcctttat atattcctgt taaatacctc tgcaattcat tcattgaatt ttcttgaata
    33541 acttgtgata atctatttag gccaagcctc ctgacatgaa agaattggac tgaatatttt
    33601 cggtatgata atttctgagc agcatttttc atagcccttc ctgtcaaaat attatcatcc
    33661 attaataaga tacttttcga atcatttctc cgactgtccc tgaacctttt tacttcaact
    33721 tcttgagtac tgtagtggct attttgaaat aaaaatgata tttcattttt ttctttaaat
    33781 aggtgcgcaa ccaagggaat ttctatcccg ccataagcta tcccacaaaa ttcactaata
    33841 ttatctacat ccaatgaatt ttcactttca aagaaatact ttaaagaaat aaaaatttcc
    33901 cagatagaat ctaattccct aaaaacacga gtaagctttc taactttatt attatctaga
    33961 tttttaagct taggaatcaa agcttcaatt tcagagttta aaatatcaag gatcacaact
    34021 aaatcttccg gttgcagaat aaaatgcttg aaattaaata gcttttcata atagctgtaa
    34081 aataactcaa tagctttgaa tagtttagaa tcgaaattca cataatattt cccatgttta
    34141 aaatcattct ctactaaaaa cttagcattc aagagtatta aaatttgatt tcttaaattg
    34201 tctagaaatg caagactgat tttaagagtc aaagagtttt ctgaatttat atattggatg
    34261 aattccgtta aaaaattttg tgtagatttc aagccatcga taaatatatt tttgtcaatg
    34321 agtttaaaat aatcatatgg tacattcgat aaataatggt agtatgtttc agaacctctg
    34381 agtaaatagc cgtcatttgt tggaagtacg tagaggtatt gaccattttt attttttctc
    34441 ccaagaaatt taatcaactt ttcttcacct aaaatccaat caacatcact aatcttaatt
    34501 cccccagtaa gtgaatcaaa aatatcaaaa aagtgctgct cataagcctc ttcaaatcta
    34561 tctaagaaat taccaaaaat cttttgttgc aacatttcct tgtcttttat aaaataagag
    34621 agttgcctta ttaaaatatt taagtcacta cttaatttca tattattatt caaaatctcc
    34681 gcactatctt ttattttcaa cacctacccc ttgtcataac tatcactggc tttgtcatca
    34741 aaatcttcaa agatatcttt cattatgtgc atcaaatctt taatctctga taacgtgcca
    34801 ttactaatcc ttatccaatt ttcacccaat tcaggatatg aagcacttat atttcttatc
    34861 aaaaaacctc tttccgttag tatatctatt attttattac catcatattt tgctttcaac
    34921 tggtataacc tgaaaccaca cgccttttca gacttttgag tagtgtattt ctccataaat
    34981 aaatctaatt gtctaaatga agactcaatg tctgaacata tacttagaga gagcggaaaa
    35041 ttttctaata ttttttcagc tatacattga ttgatattag aaacattgaa aggaattact
    35101 tttttttcta atttttttac aattttttcg ttagcacata tatagcctat tcttaatcca
    35161 ggagcacata gtgacttcga tattgaggaa caaacaatca aattagtata tttttctaca
    35221 aatggtatca ttgtataatt aaaaaaatca tatttatatg gcaacatgct ttcatcaatc
    35281 aaaaaatatg tttgtggatt gtttaaaaga agattttcta tttgattttt tgttaaagta
    35341 gccgtagtcg gattatttgg gttacatatt atcataagct cacaagattt agaaatttta
    35401 tctatttctg taacattata attataaata tctgacaaag gtgccgaaat cactgattta
    35461 ttataccttt ttgcagaatc cccatatccc caaaaagtag gggttaaata tcctatatta
    35521 ttttgaacca agttcgcaat tataatattc ataccctcta aagaaccgtt tgtaatcaag
    35581 aaattgttac tggctattgt taatttagaa gacaaaactt ctttaatact gcatgatttt
    35641 ttttctggat atgtgcttat catttttttt atagtttcag aaggaaataa aaatgagtaa
    35701 tctttcaaga gtaacctatt gacgttttca gataaatcaa ttatatcttc cacctttttc
    35761 tcgttcaaaa ttgctaatcg gtgaacattc ctttctaaat gtttaacaac attccttttt
    35821 tcttttttat atcctaaata atactctcca cttgctttcg atactgggtt ttgatatagt
    35881 aaatttaaga attcattttc atttttggtc gttaatttaa tattatacgc tctttcaatt
    35941 attttttcaa tgtcctccca tgccctatat ttcagattat taacataatc ttcatcacca
    36001 aataaaactg tagaatctgt agtcaaaata tttagtaaga gacgttgttt catagttctt
    36061 gaagttaaaa agttcttcgt ttttttaata tcttcaatct taactttctt agaatctgat
    36121 atgaacggcg gattatccaa aaataattca acctcactgc ttagataaat aagtttgttg
    36181 ctcaaaggaa tatccttatc tatcggtaaa ttttcttgaa aatgaaataa ctttgtaaag
    36241 tcacatatca accgctgatt catagcaaca aatgaatcat cgttaacaat aagacaaaca
    36301 tcaaaatcag atgaaataga caaatcatta ctaccatttg aaccgtaagc aataacatgg
    36361 attccctcca gattatcaca atactgattt agttcgtttt gtaattgata aacatatttt
    36421 ttacatagct cattcattat aataattatt cctatcacgt tttactttcc ctgtagaagt
    36481 gtgcgggata tttttaacct tcctatattg atcagggatt ttataatctt ctagattatc
    36541 tttgcataat tttattattt cacttgcttc ttgattcaaa tctttctctt catcattgca
    36601 aatagtatat tcaagaatag atattaatct cccagattct attttaggat aaactattac
    36661 ttcggatata aaaggtaatt ttcttactac agattctatt tcttccggaa atatattttt
    36721 tcctgatttt atatacctat tgtcttttct gcctaaaata tataacctgt ttttatcatc
    36781 aaagtaacca atgtctccag tccttaacat acctccaatt tttattttag aagtaagctc
    36841 ttcgttcaag taatattcaa ccataatatt aggaccagta acacaaattt ctccctcttg
    36901 ggtgttgttg ctacttgtat caatatgcac accaactcct gaaattggat aacctacaca
    36961 cctaggattt gcatataatt cttctcctcc taatacagca actctaggag aggcctctgt
    37021 taaaccataa ccattaaata aatcaatttt tggccagttt ttatgaaaat ctgttatata
    37081 atttggagga caaaatgcac ctacaacctg tactaatctt aatttcccta acaattgtct
    37141 ataattattt ataaatttaa tagagttcat aaacaataga aaatcaggta tagcgtataa
    37201 aatagtcaca ccgtatgtac ttattaaata ccctaatgaa ctaacggtcg gaattaaatc
    37261 gcttaacaac actgaatttt ttgataacaa actatttatt aattctgata tcaatgacga
    37321 cgagtgtgtg atttctttta ttatgagaca cctatcttct ctagtaggaa taatatattt
    37381 ttgaatgctt ctagtattag ataaaatatt atcaagcgat aaactaatcg cttttgaaac
    37441 tcctgtagta cctgaagaga gcattaacaa ttcaatcccc ttcaactcct catgtttcgg
    37501 aaatgattta ttacactcgt atataaaata ctcttctgaa aaaacactcc catgatatat
    37561 taaactatac cctaccaaat taatttcatg gtcagaaacc atatagttta tgtcatacct
    37621 ttcacagata tgttgtaatt tattttctgg cgttctagca tacactggca taacaacacc
    37681 atcacaacaa ttaactacca gaaaaagaaa gaaaaagttt atttttttat tacaacttat
    37741 agcaactgct tcttgtgata agttgacaat atctgcagta agtattttag aaatttcgag
    37801 aattctccta tcaatttcat ccctgccaaa ttcaatgccg tcatatatta tatttccagc
    37861 ttcctttgtc aaaataaatt tattatagag ctctttactc attttttaac tctctcctac
    37921 aaatctatcc cctagatttt ctacttctat aaccattttt tgtagttctt caattgttaa
    37981 attaggattt ccagacataa atcgtaatgg acataattca aaccctctgt atatggtttc
    38041 tgtattatct attattggaa attgatgtag gtagtatatt ccttcatctt ttagtctgtc
    38101 ataaatactc ttattaatgt tatttatatt ctgtactgat gataagctta cttcttgatg
    38161 tttatcacct atatacatga acataactga attaatatct gtcctattta ataatattaa
    38221 cttagaactc ttaagtatta gatcttgcaa ataattcgtt aactctattc tcttgtctac
    38281 catcgctcct attttctctg atcctaaatg tttagctact aaccacaatt ttagagatat
    38341 ccaactttta cttcccaaaa atggagtcgt ttgcccaagg gccaagtttt cattcataat
    38401 caaatctgat tgagagtgaa ttagattaag cgattgaggt gttttcacta acaaaacact
    38461 tatgcaataa ggaattccta aaactttatg cggatctgtc gaaatactat caaatttttc
    38521 aattcctttt atcctatctt tatacttttt agaaaaagct aatgaaaatc cgtgacaagc
    38581 atcacagtgt aaccaaacat ttggggtaag tgtctttacc aaatctgcta cttcagatag
    38641 attatcaata gtcattgttc tactatctcc agcatatgca accactgcca ttatttcatt
    38701 agaatggttg attagtgctt ccctaagttt cttcaagtta tagcgataat tttctgtagg
    38761 aacttcaata atattattcc ccaatcccag ccactttaaa cttgatgcga tactataatg
    38821 accaattcct tttggcacaa ttaccttata gtttctgggg tttcttacgc ctaattcaag
    38881 agtatttcca tctttatttt ctcttgctaa aagcatagct gtagaattac ttcctgtacc
    38941 accataggta acgatgccgc ctacttccat aatattatga acatcagaag tggaatatcc
    39001 taaaactttt cgtaaccact ggattacatt tatttccata atagtagcaa cgggagcgca
    39061 aaaagatgca ttaatcaaat tttgctgtaa taaatcacta agcaaactac ctgaaagacc
    39121 gcctaatgaa tttcctgagt caggaaaacc cataaaatta ggggaagaaa aatttgtaca
    39181 gtaaggaatt actttttccc tgaattcttc caaaagttgc ggaagattgt ctatactctc
    39241 ttctaagctg agaaaattta aatcatcgtg ttctttcatt tttttctgag aaactttttc
    39301 gcttaattta aaatccaacc ccatatttaa aatgtcattt gcgatagttt tcatatcttt
    39361 tacattttct gaactcagaa aaaactttga aatttcgttt tcattatcca tgtatgagtt
    39421 tgcctcctac caaatttcat tatttatatt ctctttattt attatcccac gcatttttcc
    39481 tgtcagatta tctctaaaaa attttgaaca atttcgaaga gaaactttta ttgaactttt
    39541 gtagtgttct ttgatatatt cttttaaaac cgagcaaaca atatcacctt gtgtcacttc
    39601 taaatttaga acattaacca caatctctga attttgagca tcgtagataa tctgatactg
    39661 ttctaaaggt tcaaatttaa atggtaatgt tccaaataaa ttatcaaata ttgaacaatg
    39721 gatggtatct gtttttagtt ttaccatgtc tgtgtatcta aagccaaacg ggataatata
    39781 cccattatca aagtaaacca aatcagtaag taaatatttt ataaatggca ttgcctttag
    39841 agttagtgaa gtaacaactg gactatataa ttttttagaa gtaaattctt ttctcagcag
    39901 accttcaact atagaattat ctaatggttt aagtacatta tacatttcta atgaatttgt
    39961 aaatgcaatt ccccataact catgacagct atattgcatt aaaaatttac atttaaatac
    40021 atcttctatt tcctttctat atacttcagg gacatactca ctagtacatt cacaatattc
    40081 aacattaaat ttaatacaat attttttaca aatctttgca tatttcaaga atatcgaaac
    40141 cggaccaatc agccatttta tttcttcctc aataagatat tttaaatccg caatatattg
    40201 attatcgtca gccctattca ttggaacttg aatcaatccc gatacttttt tcagactgcc
    40261 atcatgattc attaatgaat catgactgta ataaaaaact gctatcttaa cagacttaat
    40321 attagaagca ctaataaatt ttcttctttc tttccaaagt gaaaagttca agtcaactct
    40381 ttcttgagga gtcttgtata aatccaatgg atgataatct gtcgtgccat tagttgtttc
    40441 atgtataaga tcttttttgc tgtaacattc tgaaataata gaatctgggt ttaatctaat
    40501 atcattctta ttcaaaattg gaatatcatc taaaactgtg gcatcattaa tgatgtttga
    40561 ataatattca ttgttgtttt ttatattatt taaaaattgt gtgatttgag gcatcatcta
    40621 ctctccttgc tcgtgataca tttatgtacc aagtcaacaa tttttccaaa cgtttccatt
    40681 tctgacatag aaattttttg tgggggaagc attatgtcaa attgttcttc aatatctata
    40741 actaattgcg tgattgtcag agaatcaaaa tctaaatcat caatcatttt ttcataatca
    40801 taaaaataat gatcttctaa atgcggatta atcttaatgc ataattcaat aatttttttt
    40861 ctaatatcca tatttttacc tttctcaaag tttgtaattt ggttgtggag ttaattgttg
    40921 ttaattataa cccaatataa tatttgtgct attttgtaaa gtacacacta atagaaatat
    40981 ttttccaaaa tacagttaaa tctcaatata attaaagtac aaaaaagcct acaaaagtga
    41041 actttttgac ttttctaatt tgcttctttt attacctcgt cccaaatcac aaaactacag
    41101 atttagagag aggttcccca tggctctata atccttctaa aaaaatctaa tcttatatct
    41161 tcgaattatc tttcaaaaat ccactattag attccaaaga tttctcttaa aaattcaata
    41221 ttttacattg acaaaatctc actgataatt tcgtactcca tttcttttaa ttcccttact
    41281 atgctaatca tatcaaagta taatttattg ttgatttgat tagatctatt tattttcata
    41341 ccaattagca aaaacaactg agccttttca atacacgctt gcaccttttc agagttaata
    41401 cctaacactt gaactatttt tttataaaca tcaaaatgtt tttttaataa tacaagattt
    41461 ttaattctca tcagaacttg aggttcttta atactttctt caatataaag tttcaaatat
    41521 tcatatactt ttattcctgt cacactaaga ttttgctcta ctatactctg tttctgaaaa
    41581 accttatgat tagctaacct ataatttata taactaaatg tatccattga attcttcact
    41641 tcttctgaac ccaaaacata gcctttaaaa actttattta tcgccattct atcacaaatt
    41701 tctgttttat ttttacatat atttattttt tctattttca gtatccagtt ttctgtttct
    41761 tcaatatcac cttcttccac caccttttga attgcaaaat atcctttaat gaactcattt
    41821 ataggaaccc aaacaattcc ataatttgta aaatcaaaaa agtcagatat ttttatcagg
    41881 tttctatcta aatcaattcc tgaaaccaaa ggtgaatgca caatatgttc ctttttataa
    41941 ctaatatact tattaataca gaatgtatct actgataaat aacaaaaaga acctttagct
    42001 aacgcatcaa ccaaaaaagg gattaaagct tcctcactag ataaatctat acgtgacgaa
    42061 tactctctgt atatattatt acattgtata tttcttccaa tgaaaaaatc ataaattctc
    42121 ttattaccat attgaagaca tatcgcttcc atatccagca tggataaata ataatcaatt
    42181 ttatttaggt tatttcctgt aagaattcct tcaatatgtg attcataggg caaaaagcca
    42241 aagcttggtt ttccaatctt taattcaatc atttttataa atctcctaat ataaatttac
    42301 tttcatcgaa ctaaactcaa attgacataa tttctgtcat cattcctgct ttaattcaca
    42361 actattctta tattatgcaa aaacttatac ctgattaacg caataatata aatttagaga
    42421 ctaaccaaga tgaattcgtc ctttttaaca atttattcag tagacttgtt cggtaactgt
    42481 aaaaagtgtt atactatttt tatggaaaca gtatacgaca aagcacaaaa acttaactca
    42541 aaaaacttca aactattgat tggtgtcaaa aaggaaacct ttcaactcat gctagaacac
    42601 ctgaattcag cctatcagat tcagcaccga aaaggtggac gtccacgtag tctgcccatg
    42661 gaagaccagc tcattatgac cctccgttac ttgcgatatt atcccactca gcgtctgctg
    42721 gcctttgatt ttggcgtcgg tgtagctacg gtaaatgcca tcatcacttg ggtggaggat
    42781 acacttcgtg cgtcaggtag ctttgatttg gaccatttag aagccccgag tgctgctgtg
    42841 gctattgacg tgaccgaaag tccgattcag cgtccaaaaa aaaccaaagc aaaaattatt
    42901 ctggtaaaaa gaaacgacac accttaaaaa ctcaaattat gctggatttg acgacacata
    42961 aagtctgtca aatggccttt tctgacggac atacgcatga ttttactctc ttcaaagaaa
    43021 gtattggaca aagtttgcct gaaacgacgc ttgcctttgt tgacctaggt tatttaggca
    43081 tcttgaaatt tcatgagaat actttcattc ctgctaaaaa ttccaaaaat cgccgcctga
    43141 gtgaggatga taagcagtta aataaagaga tgtcagcgat acgaattgaa attgaacatt
    43201 ttaacgctaa attcaagacc ttccaaatca tgtcagtccc ttatcgtaac cgcagaaaac
    43261 gtttcgagtt acgggcggaa ttaatttgtg ccatcatcaa ttatgaagtg aactagattc
    43321 tgaacaagtc tagtataatt ttaccacaaa gtaacatgat ttgcaagcga tttcaataat
    43381 aaagatatat gattatcctc aggaataaat aaatttgaaa gttctataat gaagttagcc
    43441 accttacctt agtcaagaat tagatgtttc actatgtttg agtaagttga tgatttcatt
    43501 tgataacagg tttgaaactg ttaggctagg tgcccaaggc taatcatagc cttggtttag
    43561 ctgaaaaaac aggttcaagg gttcctgttg tcaaatgaaa tgtgatttaa ggtataagaa
    43621 aacacctctg tgctatactt gttgttcacc acaaacacaa ggaaaggcac agagatgcaa
    43681 gaacattata ccccaaaagg gaaacatttg acaatagata accgtcgctt gattgagcgg
    43741 tggaagaatg aaaataagtc caatcgtgaa attgcaggct tgttaggaaa ggcgcctcaa
    43801 acgattcata atgaagtcaa aagaggtaca actttacaac aagtgagaaa agggctatac
    43861 aaaaaggtct attctgccga ttacgcacaa actgtttacc aattcaatcg aaaacggtcg
    43921 gtgaaaaagt taattttaac aaaggaaatc agagagaaga tcttacacta tcataagcaa
    43981 aaattttcgc ctgaaatgat ggttaacaag aagcaagtga aagttggtat ttcaaccatc
    44041 tactactggt ttcataatgg tcatttagga ttgacgaagg ccgacatgct ttatcccaga
    44101 aaaaggaaag gtgtcaagaa gcaagctagt tcgaacttta agccggcagg taaatctatc
    44161 gaagaacgtc ctgacgttat taatcttcgc ttggaaaatg gtcattatga aattgatacc
    44221 gtcctactga ctaagataaa aaattattgc ctgttagtct taaccgaccg gcggagcaga
    44281 caccaaatta taaggttaat tccaaataaa actgctgaat ctgtcaatca ggcgcttacg
    44341 ttactattag gggagcatcg tattctgtcc attactgcag ataatggttc ggagttcaaa
    44401 cgattgtctg aggtatttcc tgaggaacat atctactacg cacatgctta ctcttcatgg
    44461 gagagaggtt caaatgaaaa tcataatcga ttaattcgga gatggttacc taaaggaacc
    44521 aagaaaacga ctccgaaaga agtagctttt atcgaaaatt ggattaacaa ctaccctaaa
    44581 aaatgcttgg actacaagtc gccaagtgaa tttcttttgg gtggctaact tcaacttgaa
    44641 atttgggctt tgtctctatg ctaaaggaat ccgctataaa tacaagtact atagccgtcg
    44701 gcattcctca ttaacacgac ccaatttgat taatcagtgt tttcaaacaa aaggtaaaaa
    44761 tgaaatctgg ctgggggatt taacttatat tccgacaaaa gcaggtactc tttatttatc
    44821 attatatata tgtttatagc agaaaaattg ttggttaggc aatgggaaat cgaatgcaag
    44881 ataagttggt aacgaatgtt ttcaatcaag cttatcatag agaaaatctc aaataagaac
    44941 tagtcggcca taccgatcaa ggatctcaat atactggagc tagatttcaa gaactcctta
    45001 aacagaaaag atgcaagtct agcctgagtc gaaaaggcaa tccatatgat aatgcaccca
    45061 tggaatcctt ttacaaaaca taaaaagaga acttgtcaat gatgccaatt tcgcaactat
    45121 tgaacgaaat ctttaaatat attgaaatct attacaatcc taaatatctc cattcggcat
    45181 tagggtacca ataactaata gagtttgaaa aaaatagtca ctaatcatcg agtccactga
    45241 aaaagtaagc tctacagttc aactaaaatg aaaaaagagg gatctatctc ctgcttggat
    45301 agattcctct ttgcttttcc ttatttttgg tttattagag ttataatcct cttcatatta
    45361 accacaaata tggttgtggc ggcttgtaac tccatgttta aaagacctgg tgctctagct
    45421 acattaagac catgtctgtt ttcaagttcc gcatttttgg cttctatctt gtagcgatgt
    45481 ttggcctttt ctttaaaata gggcgcttcc tgaaacctct tctggaaaat atgttcatcg
    45541 ctcttaaggg gtatcaaata agtcttagac ttagcccctt ctttataaca gcccatattt
    45601 gacagtgctt gatgtcaaaa tagtgggttt cctgagccgt ccttcttcct gtcttttcct
    45661 tctttagtgc catatgccct tctggacaaa caaagagacc tgcgtccttg ttatagaaaa
    45721 actcatcttc cttcctacga aagccttttg aaatagttgg atatggccta gcgactcaat
    45781 gcacacgttc tttcttggta aattgcatat tatccttccc agagtaggcc ctatctccaa
    45841 caatagcttc aatcgtcacg ccattatcct tagatttgtg atagagttct tctaaaacag
    45901 gaccatcact tttttcaccc gatgtcacca cacaggcagt aataatccgt tcatcggtca
    45961 tggcaaaatg ctctttgtac ccgtaaaagg aactatcggc tgacttatgt ccaattcttg
    46021 cttcttcttt gacagaggat tccaagtgct ctaagtcatc ctctacagct tctttaaggt
    46081 aattgaattt tgtgagatag ctggtattcc agtcaattcg tcatgcttct caaggactga
    46141 tattaattct tgtgtatatc ttaattcagc tactagagta tcttcctgag gcttactagg
    46201 aaattctgcc ttgatatatt ccgaatactg ataaatcgtt ttacgcaagg cttttgagcg
    46261 ttctcggagg acttcttgag gtttcttgtg attgtaatga actttggtat gagtcgcatc
    46321 cacaatgaga atgttacttt taatcagacc gagctctatc gcaatctgaa cagatttagc
    46381 gatgagcaaa tcaagtaatc gttcatcttt gttccgaagt tttcggaatt tagtcaatga
    46441 ggacggttca ataacaggag ctagaccaag gaagtatttg aaggtcatac cagaaaagga
    46501 gcgctccacc acatccacat cggacaactt atagatgtct tttaataaga gatacttgaa
    46561 catcatgata aggagagagt aggaacgaca tccgaagtca ggttgataat tcttttccag
    46621 ctcgtcataa ataaaactaa aatcacagag ttccattagc tgtcgtaaaa aatgagtttt
    46681 gggaacaaca atatcacaca gagtagaata gggactaaca tcgattatca agcataccat
    46741 cacctcatct ttagtatacc atcatacgat gactttttca gtggactccg aattatctta
    46801 actcttgaca agtccagtga tgcaatgata gagcatagac aactttaatg atttggggtc
    46861 gaagcgtaat cgtaaaatag gtaaaatcgt ctttgaatgc atttttatta atgtttgttt
    46921 tagaagttaa accgatattg gcaaccataa acagaaaaga tatccaaaaa aatttgagtt
    46981 tgtcttcagt ctgatttata tttcattcat aatttcttta ttgatacact catcaaaaac
    47041 cttaaataat tgtccaagct ttcttattgt tttctcatac tcatcaagaa cattaccaaa
    47101 ttcctgttgt aacttcaaaa gttcttcatt gacttgttct aaagttgttg attctgtcat
    47161 gttcaattta gaaaattcat gcctagctag tttttggcta cccgaacctt cactcttaga
    47221 attgataagt acttccgcca tcttatttaa ggtggcaatt ttttcatttg tttgagtcag
    47281 ttttatatct agctctgcta tttcggaaac caagttgtct ttaatgtctt ggtatttctt
    47341 atctgtctca gttaactcaa tcaagaggct aatctcagaa atcttttctt gaagtctttc
    47401 aacagtcggt cttctgtatg gtattactcg actatcgttg gttagctgcc taatcaaggt
    47461 tctccctttg atatactgat tcttatccga atgttctttg ttatagacaa aatatgaggt
    47521 tgtctcacga atgtagactt tatatttttt ctgattttct tcttccataa tatccagttg
    47581 atagttagga atgaaaataa gaccactctg atttatacca aaggacactt tgatataaat
    47641 cccctcatca actaacttct caatttggtg ttctgtaagt tttacttcaa attcatgaac
    47701 ggcatctcgt ttttccttaa atgtctcaaa ggcttcctca atttcttcag tagatacctt
    47761 ctccttatct cgttcttctt gaaaagcacg gtactgtgcc tgtagatttt ctattccttc
    47821 tgaaacacct acttccttat ttttaaaata atcttgaaaa aaattgacat catataattt
    47881 ctcatcactt atttttttat gactcagact gaattgcttt ccattttctt caagtataaa
    47941 gattacattt ttttgtttta agtcaatggt tagattcaat tcttttgatt ttgttagtaa
    48001 cccttctaaa gaattgacac agttcaacaa aaattctaaa cgacttgcaa tctcttgctt
    48061 ggcaaaatgc attctaaaaa aatcttcatc atataaatct cgtttactga gttgacgtcc
    48121 tcgaattggt tttgtcattg cccgatccgt catcatgaat cgactatgct tctgactaaa
    48181 atcaatctga acatgcaact gctttgcttt ctctaaaaaa tcatcaaact atttagattg
    48241 ctgcatcaaa aaataaagac gttgtttcaa ttcaaactta tgactagatt ccctatattt
    48301 tttataacct cgataagaat aacgtttctc aataattttt gcaccagcca ttttagaaat
    48361 acggtctgaa atcatacgga ggtttcgttc caaggcatag ttccatatca actttttatc
    48421 tgaattgcgg tcaatagcgt tgattaggat gtgattatga acatgatctt tgtctgtgtg
    48481 agttgctacg ataaacttaa aacgacctcc tgtcaattcc atcatggtct cataaccaat
    48541 gcggttaatt tcttcaggtg tcagattatc ttcaggagaa aatgattgga tgagatgatg
    48601 ggcatgaata gtttgttggt gtttttcttg tcggtcattt ctggactcgt acaacttgtc
    48661 gttattagta aagttaacat tgtacatttc taccatttct gtatggctag gaaaatctaa
    48721 gtaattactc atgccaaaat cagatactaa ttttagatta tctgttttat ctggattgag
    48781 gatatattta atcaaacgcc tacgatattt ttttccgtgc gtcgcaaagt gtttagtaac
    48841 taccatgaaa ctccttcagt cttttcacct ccacttgaaa ttctttgtcc acttccttaa
    48901 ttaactctcc gactccttta ctcaattctt gtaactgttc ctgagaaatc agacggcttt
    48961 gattgatagc acgcgcaatt tgattaatgt tatttccgat ccgtctcaat tcaaatacta
    49021 actggtcata ggtatccgta ttaatggtga caaatgacat attgggattc agcaacactt
    49081 tcctggcata gactgaaaaa ttttgacagt gactcttatc gattcgctca ttcaattgat
    49141 gtaattctga atctgttaga aatacttttt tgagattggt acgataacga taaaccatag
    49201 tagcctccta tctcatgtat ttttcacgaa acccacgact gagtgactgt acttgattga
    49261 cttccgcaat caattcttga acgcaggtca ataagattga cacgtgttct tgagtcactt
    49321 ggtgattctc tcttgcgata atcaaaacca aatgcacatc tcgactgatc tgttcaaact
    49381 tttgagactg ccaaagggaa aaccattctt tggcagctaa ctgtttgtca tcagtcatca
    49441 aaattttatc cctgacgaat gatgaaaagt gacgataatt atcaacctcc atcatttttt
    49501 caatctgttt tagctcatct gcggttagat ttacctcttt tcgaatgtca cggtactgtt
    49561 cagacatctc ttttcctcac tttcatcctt tctcggataa accccgaccc cgtgtgtcat
    49621 acgggaaatt tcttaaagtc cttgttcggt ctttgcgagc tcaggcattg tggtcacaat
    49681 acccaaaaaa tcatatcgcc agctaaccaa aaccttccag ttttgacagc taaccataag
    49741 ataacttggt ggcttcgccc ccaaaccccc agtgaaaaat tgaggtttta ttttcttagg
    49801 aatgatatta ggacaacagg gatgatttgg aaaaggtatc acattattga aaggaaggta
    49861 agaaaaaaga gagcaaaagc tctcataaca atccatttaa atactacaga gtagttaaaa
    49921 attagtaact aatattttat ataataagaa tctttctctg tcttattttt tataacaata
    49981 ccttttttat caaatgtacc tatcacgttt tttcgttatc taatatctgc attgtaactt
    50041 cattcaattc atatattgct ccgtctacaa aaactgtatc accataaatt tgtagtccgg
    50101 tcgactgaat tgcgatacca cagtctattt tactgtaata acctctaaaa ctattatgaa
    50161 aatgtggctt aaaaaaacaa gcacctaata aaacaaatat aattaccgtt aaaggaaaaa
    50221 gtaatacagc atgatcaggc ttatttagta gtctatatcc atcaactttt ttcatagtag
    50281 gaagcttttt taatataaca gacttatcac taacataata attttcttct actttaaata
    50341 tttcttcagt aattggttta atttttttct ctttgtttga aattaatatg tcatttttag
    50401 aaaaatataa acactcttct ttattattat aaaaataacg cttatagcaa ttataaaaat
    50461 cgaaattatc aataaaccct tgtagccact ataaaaatct gaattataaa ttatccattc
    50521 tttttttgtg tagcttactc tattatagat accattatat tcaacattac cactttttat
    50581 ttcaattttc attatcaaaa acttagctat tttattgata atgaagtcac tatattcaaa
    50641 ataaggaata agaagataca aaataagaaa cacttttatt aaggtgatca taaaattagt
    50701 tgtagaaaaa taacttatat tctgtatatc atcgtgtcta tcaaatatat aattaaataa
    50761 ataatcaaaa ctatttgtat atattacctt ttcagatacg attagtgcaa tataaaagaa
    50821 aggaacaaaa ataaaaattt tatattttaa atttaaaaat tctttttcaa aattggagtt
    50881 tatatcttgt tgagttccga acaaattttc taaaaaatta tttgataata tttttttata
    50941 tcttcactta taaattgagg aacaatactt attaaaatga gagatacaaa ggtccaactt
    51001 aacaaagatt tttctattcc tactaaagaa aaagtaaaca aaggaattgt cagatagctc
    51061 aaaagataca cagggggctt cctagctata tcgaataaaa tcttcgataa aataaaacac
    51121 attactacta agaatggaaa actataagct gaaattccta taccaggtat aattaactcc
    51181 ccaaataaac tttgtaatat tgtttggaaa aaaatcccat aaaaatatac ttagtacttg
    51241 taagtaacga acttaaaaaa catttccaaa atgttggaga atatttctta tttaactgat
    51301 cagataaaga aataaaataa tatttcatgt ctccacgatt tattatatag tatataaaag
    51361 aaatgattat ataacttatc cttacacccc aatgcaacaa gacttgtgga atattactga
    51421 taaagcaaat aagaattgga atctccaaaa aaattgatat aatatactgc catttcattg
    51481 gtctttttat aaataaaatt ttaactattc tcatattctc tcctaatttg atatttccct
    51541 tacatcatct tcctatattt ttctatatcg gattgcttta caaaatataa gttccccctc
    51601 gtacgtgtac acgcaacgta aaatttactt ttggtttgtg aagaaagttc attcaagaga
    51661 tcagctgcga ataatttgta tgatgttgga tttaatacta cacaaacatt gtcatattca
    51721 gagcctttac tatcccccca attctgactc ttgcattcat aatcataaga tttttgataa
    51781 aaaagtttca taatattgtc atctgtcatt attgattcta ttttttctgt gaatcgataa
    51841 gagtaatttg ggaagatagc ttttcttctc gctgtgataa aatttcaata gctaaattat
    51901 caacaataaa gtcacaaact attttgggac aacgataact ttttgacaaa ctcgataaat
    51961 caatttcata tcctgaatca gaaataactt ttaaccaatt ctcaaaactc gaatggatcc
    52021 tttttccttt attacctcgc cttgaagtac taaaggtttt ttgataataa tctccaaata
    52081 aaaatacttc tgcattaaga ttacttaaac ttaaaagcca atcaaaatca tctgactcaa
    52141 aatcctgaca ctcatctaca taaatacaat caaaaaattt atcaattcta tccaaatatg
    52201 aattatcaaa tctaatttct ttcctcttat agattaatga accccttaat agagatttag
    52261 aaagttgatt ctgaacaatt cttccagtat tatctatagc agtcttatca aattttcctt
    52321 gagttttata atcaaaattt attccttttg gtcgtttccc taaatatggc actaagcaaa
    52381 aactataaag agactcaaaa acaccaaaaa taaaagtaga ctcaggaatg tagccaaatt
    52441 tttcaatcaa ctttgctctg attgtattct ggttcgtctc tgtatacgta aggataagat
    52501 ttcttttttg aggatcgatg gtttcaatta ttttagttgt tttgccactt ccagcaacag
    52561 catgaatcaa tcttttatta tccattcaat cgcctcttta atataattgg gtataataaa
    52621 tttttccctt atattatcag tttccatttg ttctagtaat ctcagtgcaa attcagcctt
    52681 ttccctgagc atgtattcta ataaatcatt agatttggtt aatcctgaag actctaataa
    52741 atccgagtta caattataaa tgcatatctc aaatgttcga ttatcattat ctaaatcaga
    52801 agaaactttt atattctgga attgttgata agaactatat tttgactgta ctttactttc
    52861 gtaatcacca tcattatccg tgataactac tactttttta tcagtaaagt tagttgcaat
    52921 ttctaaatac ctctcaaaac ttaatccatc tacagaaata attgatacat taaattcttc
    52981 aggctttttg gagtggagta tttcgaaaaa cttctctact aaaatatact cagcattccc
    53041 ctcaacaaga attatcttct tacctagaga gaagttcaat aaattttgat tagtagattt
    53101 cttgaaaaat cttacagtat cttttttcaa acctttaagt ttagatatct gaccattatc
    53161 taaaaaaaga agattgtcta cacccaatct tgaagcaatc atatttgaat gagtcccaat
    53221 aaaaacttga acacctgtat ttgagcttag cattctaacc aatttctgga ggttttggaa
    53281 gctcaaatga ttctcaggtt cctcaataag tagtatttta accgtttcct tgagatgact
    53341 gtatgcattt tcaacaccta ataatacctt ttctccttgc cctaaatttt ttatatctac
    53401 accatttttt acagctgata ctgaatttct aaatgaattt tctgattcgt caaaatgaag
    53461 ttggaattct gaagcattct ccttcaacag ttcatccttc cttaaagtct ttaaaaaatt
    53521 aaatgaattt atcctgtatt gatgattaac ttttgctcta ttctcagctg atatattatc
    53581 caaatatacc tcatgaatac gtttttgaat ttcttgttgt gtatcaataa gacttgtatt
    53641 tatcattgaa tgtagaaact tatatggttt gttgtaagag gaataggttt tccctgaaaa
    53701 tgtcaaaaat tcaactctat aaaactcaaa tggaaagact gtccatttac tatcatttaa
    53761 gacagaagta atttcagcta tataatcttg attgggaatt atttttaatg aaagtccaaa
    53821 agctttgatt ttttgagagt tatgtttccc ttcaatattg aagttagagg aaatttcagt
    53881 acttaattca tcaaaataaa tctcaatgaa gacctcaggg agctgattta tatcccttgt
    53941 acccataaat tctaaaatcg cttcttgatt aatgatacta gacaaactac ttctttcaat
    54001 ttgactgtga ctaccactca gcactaaacc aattccgtat aatagagttg atttcccagc
    54061 accgttctcc ccaacaaaaa tattaacttc agaattacaa gtaaaatcaa cattctgata
    54121 acgtttaaag ttttgtaata ttattcttga tatcatacag actacctaaa cctcgcatat
    54181 tagtttgaat agttatctat taatattata tcacataaat ggtgttaatt tttcaaaatt
    54241 gtaattacag ataagatgaa tattgcttta ttcttgcatc ttaaaaagat ttttacataa
    54301 ttgttgcata ataaagcaat aggagcttta gcttatattt tctagtattc gtcttaaaga
    54361 acaccaaata gataaacact attcctaatc tgagctatct aatctattaa aaatcaatag
    54421 aacttcatac aacaagtggt aaagtagtaa atccgttcca gatcaaaaaa ctcattctgc
    54481 tcttgcaaga acacttgatg ttccaacaac atattttgaa tcagtataca agattatgat
    54541 cccctatctt cagctctctt caaaaaatta agattctgat gctgaaaaaa gaagaatcct
    54601 tgattttatg agtctagtaa atagtgaata cccaattgat gaaagtttta attatcaaaa
    54661 ctatatttca aatgcagaaa ttccagcaaa atatgaaaac tatgtaaaaa aaatagctaa
    54721 acacttttat aatgataaca aaaaaataac attatctgat gatagtgtta ttttttgact
    54781 ctataaaact tgtagaaatt taatccatca catagattat acaatttttc aaacacatat
    54841 aaaaactttc ttaaaatcat tttaaattac aaaagagaga atcacactct gattctctct
    54901 tttactatgt taagtatcaa ctatagttta acattagcct tcattactta acccattcac
    54961 cgttgtagtt tacgtaataa ccacctactg tggtattaac agctaaagca cctgaaccat
    55021 aggcatagta ccatttacca ttgacttgga accagcctgt cttcatatct ccattacttg
    55081 catttaggta gtaccaagtt gaaccatctt tcatccaacc agtagacatt gcacctgatg
    55141 aacgaaggta gtaccaactg ttgccaacat aagcccaacc tgtcttcata tcaccatttt
    55201 gaccatctag ataataccaa gttgaagcat ctttcatcca accagttgcc atagcacctg
    55261 atgaacggag ataataccag ttattaccta gatattgcca tcctgtttgc attgcagcag
    55321 ttgttgtatc tagataatac cagcttgaac cgtcatatat ccaacctgca cgtctttcac
    55381 caccaagata gtcttttcct aaataacctg tttttgctaa gtagtaccag ttggattgat
    55441 cataaaacca acctgtcttt aaagaatgat ctttatcaaa gtaataattt gcatatttaa
    55501 gaacttcagg accttcaaat ggttcaccat actctttgcc aacatttaat gaatccttag
    55561 catctaattc cttccaacca acatattctt ggagacttcc atcttgtcca aaatagtacc
    55621 acttgtgttg aaggcctatt tcattaactg gttggttatc taataaatta tcacgataac
    55681 ctgttccagg aatttctaag tattgccatc caactaccat ttctccttta ttaccaaaat
    55741 agtaagtttt tccgtctatt ttatgccaat agattgcttt atgatcatct tttacataat
    55801 attttctatt gtccttatca acaaattggc cacctgtggt atctgcaaat actgtatttg
    55861 tagctaacaa accaaagaaa aatgctgtta gtccaacttg catagttttt ttcaaaagtt
    55921 tcatttatat acccctccaa tattagatcc actcaccaga tgaagcgaaa ttataaactt
    55981 taccatcgat agtttggcta cctgtaacca ttgctccact tgaatttaga taataccagt
    56041 ttcctcctac ttttatccaa ccttttttca tgtttccatt agtaggatct agatagtacc
    56101 atgttgaacc atctttatac caaccagtct tcatatcacc atttttatta tctaagtaat
    56161 accagttgcc tcgtacatat ttccaacctg ttgccatcga accagatgat tcaaagtaat
    56221 accattttcc atttactttt tcccaatctg tacgcatctt acctgaagca tctagatagt
    56281 accaagtatc atttattttc tgccaacctg tttgtttagt actgttctta taatagtacc
    56341 atgtaccact aatcaatttc caaccatcaa tagaatgtcc ttgaataaca gagtagataa
    56401 atgataaagc cttttcattt aacttaacag cagaattcat ctgtccagca gaactaccag
    56461 acacatgaac accaatcaat ctaaaactgc tgtcatatac gccagctcca ctagcacctc
    56521 ctagagtatc tatttgatac attagaaaat ctccagtatc ttttacaata tccttagagt
    56581 cagtatacat ttgcttagca ctatttacag caggatatcc agtaatagta gcccctgtac
    56641 ctgaaagatt ccctagatta ttcggaagac ctagtgtacc taattgagcg ccaattggtt
    56701 cttccaaaat caaaactgct aaatcatacg tagtaagctc atttgaagct gtgttttgaa
    56761 attcttttag ataacgaact tcttttacct ttatttttcc tacaggattt tcgttcggag
    56821 tagccgcagg gataacatat acagaatccg cctctgttct agaatcacga tcataaacaa
    56881 catgagctgc tgtaaccaaa acattatctc ttatgaaact agcactgcct ctaaaactag
    56941 cattcatact attaaattct gcttttacgt aagctgatgt agaataagga tactgtaaag
    57001 tattcccaat cttaactaaa tcattgttgc caataatgac ttctgactga tttgtataat
    57061 atttaccata agtcggtgaa atatcgggaa gtgaaaaatt attagttcct ggactctctt
    57121 gtaatgtttc acttacctca tattcttcac ctgtactaga aataacagtc aaagcagata
    57181 ctgtcgacaa ctggctagcc aataaagtac tcgcaataat tgaaataccc aattttttat
    57241 aaaaattttt cttcattatt tttatcctcc taatgtgatt atagcatacc attctatact
    57301 tttcaatata ttaattgaga aaatatagca tcttctcact aatctagtat actattgcat
    57361 ctgtcaggaa aatacacttc aaacttctta aatatatata aaatagacca ttccagaatc
    57421 tactttgatc tatattaatt ttgatcacaa tttttcttct tagtgatgta tatctttttt
    57481 attttgatat taccttttat ttttaatccc tttattattc caaaattaca gttgcagaga
    57541 gttcgttatt gcagtaaata tctaattcat tttcagaatt accactaaac attccaccac
    57601 ctttttttct aaacataaat ttgacaaaat aaacttctaa attgccttca tactctacat
    57661 caacttcaaa attagaacct gcttcaatgt cttctatctg aacagaataa tcatttagaa
    57721 aatctcttgc aaaataattt aatttaggtt ttaaaaattg tggcactgta ttgtaataca
    57781 ttactttctt tatttccata tattttttct tccagcctct tttaatttta caataatttc
    57841 atatacaaag tataaatagg aaattcttta tagctttctt ttgtctcatt atcaagttta
    57901 ttccagaaca aatcagcttg tggtttcgat tttaataaca ctgatgaacc gaaacaaagt
    57961 tcatagttat cattactatt tactaaaatg ttactcagaa tctccatttc tttgctgttt
    58021 aatttacgaa ctctagattt tatttgaagg tcatttatta tagccatctc acaatttttt
    58081 gagtatttta agttccagtc agaaagacat tgtgcccaat taagcaataa ctcacttctg
    58141 gaaacatctt ctgccttatc agcagcaata actattttta taatagtgtt gttagcatct
    58201 tcaaatttca agccattatc aactaatctt tggtaagagg agataaccga atcaaaatca
    58261 caattatcta tttttagcca gtcatttggt tctaaaactt caaagattga aatgtaggac
    58321 gaatcttcac cttcacctct cctacaccaa ggagtttcag taaaaatgtc tatcatagtt
    58381 ccaatattat ctgtctcaaa gtcatataag gtaataatgt ggatattagc aattcttagg
    58441 tgaagtaatt ttgattcatt ataatttaag gcaactttat tctttagaat aaggcctaaa
    58501 ttgagaatat ttagatttct tagagattgt ttatcaaagt aagttagatc aacctctttt
    58561 tgtatcctca tattttccat gaagtttgaa atctgtacca attcctctat ctcagtctct
    58621 aaatcacgtg aagtaatatc caatattgac tgttcatcta gttctattat attaccattg
    58681 agcttgcaat atccgaattt tcctagttct tgaaatgcct gagtgcactt tatggctttt
    58741 gataacatat taggtcttgt gtagttaaat gtgaattgtt tcttcttaac atcaaatgac
    58801 attttaaaac cttcaccaaa atggagttgt acactcccat cagggaatct atgccttttt
    58861 acattttgaa aaatagtatt ccctattgta ataattagat ctgtttcctc gtaagtttcg
    58921 acaaccttta ttgtattttc aagtggtact tcaataccag ttaaaggatt tttataataa
    58981 atgaagagat cattttcttc ctgatagtta aagatctctc ctttttcttg accataataa
    59041 tagaatttaa ggttactatc atcagagata tcttcaactg aaataccatc aacatttatg
    59101 aagctatatt gcttacgact atttgttata aaatcgacta gcatagggta cagtttttgt
    59161 tcgtctaatt catgaatctg tacagaaagt ttcttactgc ttgttgtttt attttttaaa
    59221 ttactttttt taatcagctt ctttatagaa agaggaggta atgatttata gtagatattt
    59281 cttaaatcac catcctcgct taaccaaact acgaataaaa ctacaccacc attttttgaa
    59341 tataattcta aatcacttat gtccaacgag aaggatttca atttattctt ctgttgcctt
    59401 gtagctttaa tttgaacagg cactttacca aatatttcac ttcttttctc actagaagtt
    59461 ttaagaacat gaatctcacc atcccagact ggagttttat cattactacc aaaataagtc
    59521 tgaagtaaac tatgtctatt tatgaatgtt gtcagatagg aaacacctaa tgtctcaatt
    59581 tgtctattat ttgccaaatt ctaacctcga taaataactc tctctatata ttacattata
    59641 ccattaacaa agaaaaacat atagcatacc accactattt tgcttaaact gaaaatataa
    59701 aaatcacaac tatactataa aatttccttt tataaattaa atatccttat ctaaattcac
    59761 aagagaaaat gtgcacttaa tgtgacaatt caagactaaa aaatcattat acaaatcaaa
    59821 ctactaaaaa tgaatttatg gtatactagt gataacaatt tattatcact atacaaagca
    59881 cccaaatagg tttataatag catgattatt gataaaggag atttttatgg attataaact
    59941 tatttctact tacttagatt attgcaaaac tcataagcgt ttgagttcac acacgattcg
    60001 cgcttataag aatgatctta tgcaatttta taactcagac tatgatcatg tcgaatccta
    60061 tatagaacat ttgacacaat ctaacataaa aacgaataca ttaagaagaa aaattgcttg
    60121 tatgaaggtg ttttataact atctaaaata ccagaacata attgaagaga accccttcaa
    60181 tcaattgcgt tttcaattta gaactgaaaa aatattgcct aaaacgattc cgtatgacat
    60241 tctgaaaaac atttttatat atttagaaca gaaagtagtt atatctaaaa ctgactatca
    60301 aaaacaaaaa gctgaaagaa atctacttat tatttccctt ttactttcaa cgggtatcag
    60361 aatttctgaa ctttgtcata ttcatctcaa agatattaat ctttccaata agacactaca
    60421 tattatagga aaggggaaga aagagcgtat cctattttta ggagatcaaa cgaccttcaa
    60481 tatattagaa acatatataa ataaaaccgg aaaggaatct aatgatttcc tattcccagg
    60541 gaaacatttg cctaaaccat tgtcagagca aagtgtacgt ttaattttaa agagaatcgt
    60601 tgaacaaaat agcttatcta aaactattac accacatatg tttagacata gctttgcaac
    60661 aatgcttcta gataatgatg tagatattcg atacattcaa caaattcttg gacacagttc
    60721 tatatcagtc acacaaatct atactcacgt atctcattca aaacaaaaag aaatacttag
    60781 ttcttttaat cctatgtcag tgattcattc tgaaatcgag taagagacat ttctgaaggt
    60841 tacagtttac tttatcttaa atcaatgttt gtagttcgac tttagttaat agattttata
    60901 ctcaacaaaa gcaaaaaaca tataaaactt cactttgaat cagcatttat actatattac
    60961 gtccgtatta aaaactccat atttgttttt ctaaaataca gctttcaaat atccttaaat
    61021 ataataaaaa gagatgggca aaatctcaat tcctgaagaa aatggagtaa atcttccaac
    61081 aagaaaacgc ataatatcaa gttttttcaa cacctgatac tatgcgtttt ttttgatttt
    61141 aaaaactttt tgcccacctc aaacaactaa caaaagttat aagtagacta tattctaaaa
    61201 tttgtgttct aacaaccatt tcaattagtt aaatctttca atctttcttc tcctgattta
    61261 agcatctctt tctccacttg attcaattct ccaaatagta aatcatgaag aacggttgct
    61321 gctgaagttg tattttcttt tgaatcatat acacaacttc tatctcgttg gtaaatttga
    61381 atgctttcaa agatagccag ttcttccaat tgtcgtgtat tatcaactag atgatttaca
    61441 atgaaatcat gatgttcttt tggagttgcg cgtgcttgat ttggattgat agcatacagt
    61501 tcttcgtatc ggataagggt gctcagatag gacaattcgg gcttggttgc aattaaggct
    61561 aattgtacct catacccctt attttttaat agttgtgctg ttttctttgg aacatcaata
    61621 gttcgtaaag ttccctctat caaaagattg tatcccaaat gactcaattc ggttactaaa
    61681 gactctacca ttttccctgc aaaatctttg gtgtattcta cactgtcttt gccatattct
    61741 tgctgcagtt ctaaatagtg tggatgctga gaacgaaaac tatcaccatc tatgataaca
    61801 atatttcctt gaaattcttt ctgtttaata cgatgaattg tagtcttacc ggcaccactt
    61861 tgacctccaa gcaaaatcgc tataggttgt ttactggact tttttcctct tgtcagtgaa
    61921 cgaagattcc ttgctaaagc atgtttgaat tcactatcag tataatcttg gatttccatt
    61981 aagctaccat ccgcttttca gatatctcta acatacgttc aattccatcc aaatagccgc
    62041 tatatctctc tatttcatca aaattttcta ctaaatagat atttgtctga atcaagtcag
    62101 atagatcatc actcattaaa atccaaggat tagattcatc atcaatacta attccctgac
    62161 tatcttgata acgatagagt cgagataata gattagcacc tctttctttc acaatttcaa
    62221 ttttcaaagt caattcataa tcttcaacag gattgagcat tttatcttct cctacgatat
    62281 cgacataaga tacattaaac ttctgacaaa tgatgtctat taattcggta gagactgaac
    62341 tcgttccatt ttcataacga ctcagactat ttcgtgaaat acctacaatc cttgcaaatt
    62401 cgggttgtgt taagtcatgt gttttacgta aggattttat gttctttcca atcatagcaa
    62461 actcctttat ttttataaat ccattatagc ataaaaaagc ataacgcacc aaaaatggtg
    62521 cgttatttct tgtttttcta tcctaaactt tacttctata aaagtcacct aaagagctat
    62581 aaatatttat tcttgtatta attttttcga tgcgcaaacg atatctacaa atacatctat
    62641 aacgattcac cttttaggat ttttattgtc aaaattgcct ttatctacaa agacaaaatg
    62701 cttataaaat agcttgaaat caaggattat cacctttttc gttgtagcaa cactccacat
    62761 gtgattatta ggctattagc aaagcgtatc caatacctca ataaagtgtt gtttttactg
    62821 atattttaac tatattgtat agtctactat ttaaatctca attaggatat tttatagaat
    62881 acccaaaatt caacaataac taaaagtaag attccattgt atttccttgt tggtctttca
    62941 tatcacgaat tttatttttc agaatattaa agttacaaat ttcatctcta atatcgttat
    63001 ccgctctgta gccattaatc atctcagtca gagttttccc tttactacca ttctttatag
    63061 tagtatttac tctttttata ctgctttcaa aaggctcata tgttttatac ttaattactt
    63121 cgtctttaaa attaaataaa ggtgtatccg gcttagcatt ccataaaata atcaaccaca
    63181 ttataacatt ataaagctgc tttgcagttt cattccactt ttcaggttgt aaatttccac
    63241 tccctgtatt gtcatattct tgtctattat ttacatgaga atcacctaca agcggattaa
    63301 aaagaggtag ccctttgtga ttaattagtt ctaaaaaatc ccttgccgca cccatgcaac
    63361 actgaataac ttccttcttg ccatcaattt tactctcagc gataaataca taatattcat
    63421 cttcaatagt tgctcctgca tcactatgtt tttgttgatt tgctaacagc ttaatatgtg
    63481 ctttaggcta aacttcaaaa tctctaacaa ttctttgtct tgtttcatgt cctctacaat
    63541 tcatttaagt tctcctttac aagtttagta actatcctta ttatactata taagatatga
    63601 aatgtaccat aatcttcatc aactagtttt tagaaaatca caaatccatc tggagagatg
    63661 acaagctgat tctccaattc ttggcaattg cttgctagtg ctactgcttc tttctctaaa
    63721 agataatctt ctgttgattg gttgaatatt gctttgagga tccgtccttc gtatttccat
    63781 tccagagcta ctagatcaga tttgatttct tgaaggctat acttgccatg cgaaatgatt
    63841 actgacgcgt atttccgaat cttaatcagc ctcttcataa agttcagcat atcattgtca
    63901 cttgatacac gttcccaagg catacaacga cgacaatctg gatctggtcc tccagtcaag
    63961 gctagctcgg ttccgtaata aatgcacggt gttccttttt gttaaaagag aaaggctaag
    64021 gctgatttaa ccagttgaac atcttcattg gccgtccaca ggattcgctc tgtatcatgt
    64081 gaatccaaga gattaaacat gacctctgaa atctgctgct tgtaatacat agactctcaa
    64141 ttgatttcat cgatgaactg gtctgtcttc ttaattcctc gtaagaaata gtccttgata
    64201 ctatcagata aaggataatt catgacggca tggaactcat ctccatttag ccaaggctga
    64261 gatgtatgcc agacttctcc taggatataa agatcaggat ttttagctaa aactgcctta
    64321 cgaaaatcct tccagaactg atggtcaatc tcattagcca catccaaacg ccaagcatcg
    64381 atattaaact cttcaatcca ataagtcgca acctttaaaa gataattctt gacctctgga
    64441 ttggctgtat ttagcttagg catatagtcc tcgaaaccaa aaacatgata gggtaagtct
    64501 ctcttattaa ctagcttttc agttgtcact gggaattgtt gaatatggaa ccaatcctta
    64561 taagcagact gttcgccatt tttgacgaca tttttccatt gaagagattg cgaaccaata
    64621 tgattaaata ccgcatccat catgactttc atgccacgat gatgcgcttg atccaccagt
    64681 tcccgaaagg tctccttgtc tccaaaataa cggtcaattt caaagtaatc tgtcgtattg
    64741 tacttgtgat tgcttgtaga ttcaaagatg ggacaaagat atagtccagt aatacccaag
    64801 tcttgcaagt aatccatacg atcaataatc ccctgtaaat caccaccaaa gaaatcatcg
    64861 ctcttaggtg tgacagatga atcccagtct aaagtccctt ctgggtttaa tagagcattg
    64921 ccattggcaa atctttcagg aaatatctga taccataccg tatttgaaac ccagtcagga
    64981 accttgcagg catcaatctc atgaagataa ggcaacttaa atccattccc aattgcatga
    65041 agattttcta gagaattttc cacacaccct ttatcgccat acaaaatatt ttgaccttct
    65101 gtatctctga gctcaaagag atactggata cgtgcaaagt caactgacac ttcaacctgc
    65161 caatggtcaa ataaggtacc agaagttatc ttgaccattt cttttgtatc ctgataaaac
    65221 tcctccataa agataaaagg gtccccatag tgcaagttga tgctttcaat gtcccctttc
    65281 ttagttcgaa ttcaaatatg gagtttctta tccttataaa gataggcata ctccgactca
    65341 ggcctatggt aaatagcact caattccatc aatttgtctc ctaaagtatt tattcaaatt
    65401 ttacgcaaac gttttcaaac tcaataaatc cagtatacta tttttgtaaa ctatttgcaa
    65461 ggaatgtccg ttgttaaagg aactatcttt taaagtatac aaaaagcctt aaaaaaggct
    65521 ttctctatat actaatcctc tttcggtttt gaaaatactt ctactcgctg agctaggact
    65581 ttgatttcta caggtaggtt atctgattta tctccgtcaa catctgactc caattcacta
    65641 tctgaagaga ttttaatatt acgcgctttg atatactcga tattatcatt tgcgacaaca
    65701 tcccctttta ataaatcagg aatgacggat aatttggaga atatagaggc atctttcaga
    65761 atcaaaatgt tggcatagcc gtccttgttt tcttcaaaga ttttcttatc agcgaagtaa
    65821 tttgtcaaaa ggaccaaaac atggctagct tcaccaacat aatttccatt ttctgtctca
    65881 accttaatgt taaagacctg atctgtcatg acagacttca tggtatttac agcataggtt
    65941 aaaataccga attttgtttt gtcctctatt tcaacattgt gaatcgcctc aggcagagaa
    66001 ccgatactaa agatataacc aaaatagttg tcatttgctt taccgatatc aatcttattg
    66061 gttaaatcaa aatccagttc gtcaattgcg ccatcgatgt cttgattgat ttccaaaagt
    66121 tttgtaatga ggttacccgt accgcctggg ataatcccta acttaggaat gtagtctctc
    66181 tcatcaatac ctgaaatgac ttcattgaca gttccatctc caccaaacac aaccactgca
    66241 tcatactgct cacgagaagc ttcttcagca aaatgtgttg catccagcgc tttttcggta
    66301 attttggttt caacatattc aaagtattct tttgctttat tctccagctt ttctttgtaa
    66361 tccaaagcct tctcgccacc agaagtaggg ttgataatta ccattacttt tttcattgat
    66421 tttatcctta attttaaaca gaaatgttta catttcgtcg tatgcaagta aatgtaatcc
    66481 tattatacaa tgaaaataca gaaaagagaa atctgacgta ctggagatta atacgctttt
    66541 attctatttt cccatcgcct aactacatcc tttaagggtt catccaagta agaataggcc
    66601 ttatccttga tccaatcagg aataccgtaa gctgcctctg ctatgttaca agtgattgct
    66661 gcgagagtat cactgtcgcc accaagtgag atggcatttc ttatcgcatc ttcgaagtct
    66721 ctactttcaa gaaaggcgat aatggcttga gggacagttt cctgacatgt ttcgttaaaa
    66781 cgatagttag gacggatttc atctaaagtt tgagatagat tgtaatcgta ttctttttct
    66841 atataatcct taattcgtct tttacactct gtaggattgt cgttaattga ttgctcgtac
    66901 tctctacaat aaccaccaaa gtaaaaacga catagaaaga tagcatcagc tgtagccata
    66961 gcgcctttga caccttctgg atgattatga gttacctctg cagaaagact cgtaagtcct
    67021 ctagatgatg gccacatacc agttttcgca taaaaaccac agtccatgat ccaagcacat
    67081 ggagaaatac gcatagctga tccattccca aagctattat aaggctcacg attatcgctg
    67141 tttagccatg cattaaaccg agcaccgtaa tcagcattcg gatacatgct gccatatttc
    67201 ttcatcgcgt caatgaaatc gtctttttgt ccaccattca taattgcttc tgtaacagca
    67261 caggtcataa ccgtgtcatc tgtaaaaaag cagtccttcc gaaataaagg aaagtccttt
    67321 gttttgatat tgttccattc gtaaacagaa ccgacaatat ctccaataat tactccaagc
    67381 atcagattcc tccttgttca ttttgatgct ttttatattg gttatctacc atatttattt
    67441 tagaaaataa catcctgttg gattttaaaa atttcatttt tttcaaaata gggttttacc
    67501 atttctttcc acctagctct atgaaaattg attgatttta aaggagatag gccataattt
    67561 cccaatgcat aaccatcatt tacttcaaca acaagtgttc tgccatcgcg agtaacaccg
    67621 atatctagtc cataagctat tggcgcatct ttccaacatg atatcgcttc atcaattaca
    67681 cttgcatcaa attgtgcatg ataatcacct gtatagggtc gaacatctaa tacgcgacca
    67741 tctaacacaa aacaacgcca ttcagctatg aattctacaa cctcactaat ccatatagga
    67801 tagtcgaaag gtagaccaat acctattaaa tcatgggttt cattaacaac tcttccagta
    67861 aagacttttg aaccagcttt aggcttaata aattttcccc aattatcagg tatattcaca
    67921 atctctccta aaataccagc ataaatcttt cgaccataaa actctttaag ctcaatagga
    67981 tagtcataaa ccggaacgtt taagcccatc atttttagta atgctctagt ctccattata
    68041 taatctacaa ctatatcttc acttgttaac tcttttattt cagaaaaaga ttgatataaa
    68101 ataacttctt ctccttgtaa gtaggcacct acttgagcat tgtatttatt aattgaaacc
    68161 tcacttggta atttactttg tctaatataa acaaccattt catcactcct atatcactag
    68221 tgttacacca atttgtaaaa aataatagca attttgctct tatttttttg agtaaatagc
    68281 ccccataata tcatcgaaat aatcaacggt atttaggagt aattcaataa cctgggactt
    68341 tgttagtcgc attccccttc tatctctagc atcttctact aaattttcaa gtttctctag
    68401 atttttatca tccaagctaa tcattattct atttttatcg gttgccattt tcatcacctc
    68461 aagttaattc tatcacaagt gtgacacttg tgtcaactgg cttttataat acattagttt
    68521 aaaagtggag aggattttta acacagtaac tttaaatctt tggtattaaa aaattttcac
    68581 aatatttata gaaataaaat ctgtctcaaa tcagttatca aatctagtat aaattatgag
    68641 cggctactct aatactttcc ctctaaacaa gaaaaagact tacactcaag ggttttcttc
    68701 ccccccttcg ttataacgtt ttgactcttt tactagcaaa ggtatatact cacaaggaac
    68761 tttggttgac tattgaatct ctccaacttc ttctttaaca tatccttcta catcttcaat
    68821 ctctacaaac attgggtcta agtgacacaa gaaatgccaa acttcgatcc ctttttttct
    68881 gtaaagaatc gcttcaccgt cttcacttcc gaaaaagctt ctgtcgattt catatccgcg
    68941 gctttctaag aagtcttttg ctttacgata gttcgtttct cttgtttcga cataggcttt
    69001 aacttcatgg ttgttaacga catatgcatc aatttttgaa tatccttcga tcactctatc
    69061 atttttgagg gataaatttg aaatctcttt ccaaataatg tttacatttt cctcaggatc
    69121 gaacataaat ttagataaag gaacaatatt tccgttaaaa ataatttcca tataatccgg
    69181 tatgttttta ggattaaaat actccacttc aaaaccatct tctgtttcca gagtgtatcc
    69241 cgggatttga gctacaaagg ctttcccatc ttctatggaa tcaaatgcta ctaaatcttt
    69301 agaataatca ttttggtaca attccaatat aaccatcgat aatctctcca ttttcattat
    69361 caggctaatg taaataagca cgtcacctga ccaattcagg ctctctgtat catctcatca
    69421 tatttcctac ttactttacg agtcctatac ccagaacaca ccttatcgac cttcggtctc
    69481 acctcgtcgc attggctgaa catctacttt tacttcgctg atgcttcaac tcgtacaagc
    69541 agtgataccg cctcagcgtg atgcgtcagt gggactcaaa aggtttgggg aaccttttga
    69601 ggattaacta cgtttctcta ataaacttac acattcaact tgttcatcat tgtccaaatc
    69661 tatgttgaga ttttcttcta taattggtag cttaaaagta atggatttta gccattgtcc
    69721 gttagattgt ttttcttcat aaacttgaat ttcagaaatc aaagctgaaa ttaactgcct
    69781 acgctctaca tcattcatga ctttatagag cttatcaaaa tagatcagaa ccttatatat
    69841 gttatctcct gtaagctttt cagcttcaat agtctgtttc tttgctttcg catcaattag
    69901 tgatgattct aattcatcta ttttgtcata catacgatat agtctatcat ctaaatcctg
    69961 tttccttctc ttataatgct tatcttcaac atctaaatta tctatttcct caattagctt
    70021 aaactttgta gaatgactct ttctcaattc cttttggtaa ttatctattt ctttttctat
    70081 ttcagaggta tccaccttca tgttgatttt ttcttgcatc atagaagcaa atttcggatt
    70141 acttactatc ttgacaatca cctctgcaac agcatcatct aacaattctt ctctaatttg
    70201 cttactgaat gtacacttat gacctcttat catctgccta tggttacaac catagtaata
    70261 aaaatcttta tactttgtgc catctttctt tttcttgata cacttgttcc caaacattcc
    70321 cactccacat atcgggcatt ttacaattcc agaaagcaag tgtgtgcgtg tatcttttcc
    70381 tttattcaca tgctcatatt tctttgcttg agattttagc ttaacctgag cagcttgcca
    70441 aacttcatcg gaaactatag cttcatgtat cccttcagat attagatatt catcttgttc
    70501 aacctgctta tattcatttc ttgtaccatg aactttttct aaagttcttc ttccaaatgc
    70561 tattttccca ttatatacag gattctttaa tatctttctt ataagacctg catcaaacaa
    70621 aggattctta ccattctgtc ttgggatttt tctaattcca tgattctcta agtatttaga
    70681 tatcccattg gctcctatcg tagcatttac atactggtcg aaaatcgttc ttattgcaac
    70741 tgcctcttcc tcatttataa acagcttgcc gtcttcaagt ttatatccat acggagcaaa
    70801 gccaccattc cattttcctt cccttgcttt ttgaatgcga tcttccattg tttgaatacg
    70861 gatgttttct ctttctattt cagccacagc tgataaaaca gaaatcatta gtttcccagc
    70921 atctttagat gaatcaatgc catcttcaac gcagataaga ttaactccat aatcctgcat
    70981 tatctgaagt gtagaaagaa catcagcggc atttcttgca aatcttgata acttaaacac
    71041 aagaacaaaa gatactccat cttttccaga ttttatatct tccatcattc gattgaactg
    71101 tattctacct tcaatagact tgccagactt cccggcatct tcatactctc caacaatttc
    71161 ataatcgttg taaatagcaa aagctttcat tcgtgatttt tgtgcctcta acgaataccc
    71221 ctctatctgt attgacgtag atactcgtgt atagaggtat acttttattt tttcttttga
    71281 catagtatta acctcaatat aatttttcta tatcatatat aattttttta atttaagttt
    71341 ggactatcat ttcaagtata ttataacact tttattagtc cgtctcaatt tgtgtttttg
    71401 ccatgtcaaa actatttttc atctcttgat tttttgctgg cgttggatcg ggtagattat
    71461 ctaaatctaa agcaccagca tattttgcaa tcagatttgc tattaaatca gccaatccat
    71521 tccagtcatt gtccaatata tacctcctct aaagttttat atctaataat tatttgttta
    71581 attaagtttt ttgacattga caagtgcttt ggattagcaa cataggaatc tcacctccgc
    71641 ctctattccg gatgagccgg cttcaacctt agaagtatca ttatcctcat tttcttcata
    71701 gcggataggg tatccctccc tatattcaaa ctcttactta tcgctcactt tctttttact
    71761 tagcagaact ttttttgccg aattattcag ccgaaagatc ttgacggata ggttattacg
    71821 ctccaaaaat aattaacgtc ttgtcttggt ctattcaatt gttaaggttc aaaatttatc
    71881 gagagttatt aatcttttta aaatttgacc atcagaaaat atttatctta atgtaataaa
    71941 attctataaa ttaccctctt atacttaaca gtgaaaagaa gtctttcttg gtaaccaatt
    72001 ttgaaataga atttgcttat ataaaaaggt caaattccca ctgcataagt agcagtgaaa
    72061 attagaccct cttggtaact gtcatctaaa agtcttctag catttcttta attttctaat
    72121 cgcctttaaa gtgtcatatt tatatttttt tatctctggc atactttgat acctttttag
    72181 acttaaagtc tttaatagtg cctttccacc tctttttatc tataaagatt ctcctacatc
    72241 ataattcatt tttttattta aacctttctg tcttagtttg tctttatctt cttcatacca
    72301 ttttaagatt gtcacatagt ggttttgata ggtcttacca ctgctttcca tgtatctgga
    72361 tagtttattt atcattatat ctgtgtgtga gtttaatttt tcttttagat ttttatattc
    72421 ttctttgctt aaccttacat ttttgaattc tccataaaaa atgggggtgg actttttatc
    72481 tatctctccc tctctctctt tatctatctc tatatctttc catgtaattc caatctggag
    72541 tacctctact gtctatcggt aatttaattt tgatatctgg caatactgtg ctagatattt
    72601 gatctttata ttcagtattt tttaaagctt gcctaataat tgaagttaaa tagaatgcta
    72661 cttctttatt caattcttta ttttttaatt ttaaacaatg aattttcata tctaggcttg
    72721 ctttatattt atgataaaag actgctccta aaaatgaaac agatataaaa ttttcaaaga
    72781 ctctataatt tttatcatct atatcttcgt agtaacctaa gataccattg tcaatatttg
    72841 tagcactaat tctaggagtt tttccatcga gtaaatatct ttttggaata gatgagcctg
    72901 ttggtactta actcgatttc cccttttttt cggtaataaa tatttctttt tattttgttg
    72961 tctgatattt ttcctacctg tcctttgtag gatgagtatt ttctagattt tcttgaataa
    73021 ctttttactt gaagttttag cttttgaact agtcgttgta ctttcttttt gtttattatc
    73081 agtcctgatc tttttaatat tgctgttatt ctctatatcc tatttttcat tcatgatatt
    73141 cttttactaa ttttatctta aattctgtgc tgtatttgcc attaaaaaac tgacctcctt
    73201 tagttagttt tttggcctaa cttttgaggg tcagttcaaa atttgcgact tttaaatgaa
    73261 ttccaatatt caattattaa gagttaatat ggtgcttgcc aataggaatc attagaggcg
    73321 aattggaaat agggtcacgt ataatttttg cttcaagatt aaagatatct ttaactagtt
    73381 tatcatttag tatatcttca ggctttccct ctgcaacaag tttaccttct ttaattgcaa
    73441 ataggtaatc agcgtatctt gctgttagat ttatatcgtg caaaatcatg caaatggttg
    73501 tcttatattt ttggtttaga tcagtcaaga ggtctaatag ttctatttga tatgagatat
    73561 ccaagtaagt agttggctca tctaaaagta ggatacttgt atcttgggct agggctagag
    73621 ctatccatac tctttgcctt tgacccccag aaagttcttc aactaggtta tttgctagat
    73681 cttcaacatt ggccttaacc attgatctgt ttattatttc aaggtcatct tttccaagac
    73741 tcttaaaagg ctttctgtag gggaaacgac cacggcttac aagatcagct actgttattg
    73801 attcagggat tattggagat tgaggtaata tagctatgtg ttttgctaaa tctttttctt
    73861 tataagaatt aattgattta ttatcaagca atacttctcc ctctaatggc tttataagtc
    73921 gagacaaggt tttaatgagt gttgatttcc cacaaccatt tgacccaata ataactgata
    73981 ttttttcttc aggtattttt atatttatat tttccaagat tattttttca tcataaccgc
    74041 aggtaagatt atttgaccac agacctttca ttatatattt ctcctgttca tttttattag
    74101 taagtatatt aagtatggtg aacctaacaa gccagttaca acacctactg gatatctagc
    74161 tggtaaaata ttttgagaga atatgtctga taacaaaact agtaaaattc caaccaatcc
    74221 agctaatatt gggcttcttt tcttgccaat atttaaggct atgggaccag ctaaaaaaga
    74281 tatacaagct attggtcctg taattgaagt agaaaaagca gttaaagata cagcgcaaaa
    74341 aattaaaaca agccttgaaa gctcgggatt tgctccaagt ccgattgcta tttcttcacc
    74401 aagttcaata atttctagtc ttttattaaa aaataaaact aatatagtag caataatact
    74461 tactattaga acaagaggta tgtcatctaa ctttgtaaaa gataaagagc cactgagcca
    74521 tctcataact tcttgtaatt catatcttgc tactttcaac aataaaaatg aggtgcctgc
    74581 tcttgtgaca gcttgaaaac caatacctaa tattatcagt cttgctgctg aaaaaccatc
    74641 ttttttagct agtaaaaata atattaaaga tgatgttagt ccacaagtta ttgaaataat
    74701 tccagtagtt aaactatttg tttttaatac caatatgcaa aagaccgctg caatagatga
    74761 agaacttgtg acaccgatta tatcaggact tgcaagagga tttcttaaca tagtttgaaa
    74821 gataaatcct gccaatccaa aagaccagcc agctataatt cctgctaata attttggtaa
    74881 tctaatttcc ataatcgaaa aactagctcc aggaacagtt tcactattta agactttaat
    74941 caaagttgaa aaagaataac tttcatctcc gataagtaaa atgaaaaatg atagactgat
    75001 tattattaat aaaaatagtg aggaaaatag tgttattcta ttttttcttt tttgaatacc
    75061 tataattaaa ttttgcatta gttattaacc cctctatttt tcatagttac ataaataagt
    75121 actggacccc cgattattgc agtaattatc cctacttcaa tttcacctgg tttacctaac
    75181 atacggccga ttatatcaca tataagcaag agctctgcac ctataaaaga tgaagaaatg
    75241 gtcattgtgc gtatatcttt gcttataaat aagccacaaa agtgaggaac tataagacct
    75301 acgaagccaa taggtccacc aattgcagta atacttgaac ataaaagcac acttgcaatt
    75361 attgcaagtg atcttatcct attaacatta actccaagac caacagccat ttcatcaccc
    75421 atagctaaag cgtttaaatc tgatgaaata aatatagcta tcaagtgacc taaaattata
    75481 aaaggtagta gtgtagatat agaagataat gtagctgctc caaggctacc tatttgccaa
    75541 aatctaaatt tgtctaagac gttattattc ggtaaaatta aaaaacttac aaaactgctt
    75601 aaagccatac taacacaagt tcctgataag gcaagtttta taggggtaag gcctgctttt
    75661 ccgcttacag caatcgcgta tacaaaaatt gcacttacta agccaccaat gattgcaaaa
    75721 cttatatggc ttatgcttga tgaaattcct aaaaaagaaa gaccaattac tacactaaga
    75781 cttgctcctg tgtttatacc gagtatacct ggatcagcta ttgggtttct agtaactgat
    75841 tgcatcaata caccgcttat ggcaagacta gaacctgcta aaattgcaaa aatagttcta
    75901 ggtattcttt tatatataat tgatttaata aaatcatcat ttgtattgcc cattccaaaa
    75961 gctgctaaaa aatctctgat attaatttct tttgttccaa gctttaatga caaaaatatt
    76021 gtaataagaa gacctaggca gattacaaaa attatgccta ggtttatttg ttttttattt
    76081 cgcatttttg catgcatttc ctaaaagatt taggtattct tcaatagtat agtttattga
    76141 aagtggtgtt ggagtgcatg aggctgctaa cggtgtatta tctggaatta cagcaacggc
    76201 accattttta attgcattta ttttacctaa aagaggatct ttttgtaaag cttcaagagt
    76261 tttatcatca ccataagtta tgattacatc agcatcattt atcttatttg cttcttctgc
    76321 agaaatttcc tttgcaaaac tatcttcact ctcaaattct tttaatgatt cagggaaaac
    76381 tagacctaaa tctgttaaat aatttgctct tggatctttg ctagtataaa tccagaattt
    76441 tgatgtatct gcagcattaa tcatagtaaa taatactttt tttcctttga tttttccttt
    76501 gatttctgga tgtttttcta attctttgga tatacgagct tcagtatttt tgattaactc
    76561 atcaccttct ttttccatac ctaaggcttt tgaatcaatt ttaatcatat ctctccataa
    76621 agtttgccaa ggtttagatt tgtatgctgc tacaggagca atttttgata gagtgtcata
    76681 atcttcttta gttataccag aataacctgc taagataaca tctggtttag aatttgatat
    76741 tgcttcaaag ttaagtccat ccaaatcgtc aaataggtta gctttaccat ttagttcttt
    76801 gattttttct tctgtccatg gtaaaactcc tttatcagca cttacaccgt aatttgcttt
    76861 tgaaaatcca acaggaacta ttcctaaagc taatgctaca tcatgatttc cccaagcaat
    76921 agttgcaact ctttcaggtt ttttatctaa tatagtttga ccgaaagcat gatctaaaac
    76981 tattttatca ggcgcatgct ctttagaagt attttcttca tttttaacag aattagaaga
    77041 acaagcgcta aaaactatac acatagctaa aatagctatt agaaaaaatt tgtttttcat
    77101 aaaaactcct taaacatatt tcaagtctat tgtatcgata ataattatca ttgtcaatag
    77161 atgcagttac aaatttaata atataatttt ttcaaaaaag gatctagttt ttatttttag
    77221 ttaaattatg tctatatttt tcattaactc atcaataaaa atttgtttgc taatatctct
    77281 ttcttctgat tttgtttcaa ggattattgc tacatcattc atatttttag gtaaatacca
    77341 accatctggc ttatctgaat atcccttgaa gcctaattga ttaaaagtag ttatttgacc
    77401 agtaccttga ttgatgtttt cttcaacttc attaaagcct atacttctct tgcataatcc
    77461 ctaacttgat cttctgtcct taaagtcatt ttctattcct cgtcactaaa attatcttca
    77521 aaactaataa tatcattagg agtgcaagat aaagccttac atattctttc taaattctta
    77581 aatgtaattg gtttatcctt tcccatttgt gccataacat ttgttgtaag tcctgccata
    77641 gctattacat ctgttttctt tagtcctttt tttgctaact gtatccataa tggtttatag
    77701 ttaagtgcca taatatccct ctttttttct tcattagatt tatttaatta tagcataaat
    77761 attgatttca ttcaatctta cattgattta gtgatttgtt ttagagaatt tgttgtgtta
    77821 ttccgtcctt attttgccat aaattgtttt aagtgggacc tcttatcctt accattttta
    77881 cctcctaatt ttgagtataa aaaagacgat agagttttta atttctatcg tctgagattt
    77941 acatattaaa ttttcatcac aaaataagac tctttaaaga atctttaaat tcattggtat
    78001 gctgcttaca atatccatta ttaaaatgga tactataaac agcacaccaa ctatttattt
    78061 tttgagtttt aaactttggt agaagtcttg aactccttat atttacataa ctatttgcct
    78121 ctataactat tatgacacga aaccaacaag caagttcaag cacctccata tctttattca
    78181 aatgaggact aagatattca caaactttat cataaacctc tttatctttt ttcataaaag
    78241 gggcatacaa cttagcaaat ttatcctaaa attttttgtt gcctttatca atcatttcaa
    78301 cactccttta aatataaaaa tgatcctatc aatctttata ttgagcctat tttctaattg
    78361 ataccttgca agaaaggaat aatagccgtt cctataccaa gtaggaatgt aataaatgca
    78421 gaaagtcata tactgtcatt cttttctatt aaatcatttt gaagtgtctc aaagcatcca
    78481 tgatggcttc ttctttttca ggtgtacact gtggaataat ttgtttatcc tttttagact
    78541 tgttgtaatg ttctcgtaat tctattccac atttcttttt tatctgtgca atatataatg
    78601 tcgaaacttt taattcaaat ttattccaaa catattcttt gatttgagca tatgttgctt
    78661 tgctctccgc acttgtcaaa ttcatctcat ccagctcaat ttcaacactt atgtgcttat
    78721 cgacatcgag tttggacaaa agtgctaccg tctcgacgtg atgcgtttga ggaaatagat
    78781 ccaccggctg gactttcttc aattcatatc ccaattcttg gtagagtttg atatcacgcg
    78841 ccatggttgc gacattgcag gagatatagg cgatgcgatc ggctcctgtt tgggcgcttg
    78901 ctttgataaa gctttctgtc aagcccttgc gtggaggatc aaccaagata acggttggtt
    78961 gaatcccatc tttaagccaa ttcttcatag cattttcagc tgtgtcacag acatagtggg
    79021 cgtttgaaat attgttcaac tgagcatttt ttttactatt ctcaaccgct tctggaatca
    79081 gttcaacacc gtagacttct ttgacatgct tggcgactga taaaccaatg gttccaatac
    79141 cagaataagc atcaataacc acgtcatctt tttttaactc tgcaaagtca atggctgttt
    79201 gatagagttt ctccgccatt tcagtattga cttggtaaaa ggctgggcca gcgatttgga
    79261 agtcatttcc caacatctgg tccgtaatat agtcttgacc ataaagagtg cgccactcct
    79321 taccaaaaat cgcattggta ttctggtcgt tgatattttg catgacagac acaatctctg
    79381 ggaactgctt gataacttgt tcaatcaatt ggtcaacacg aaaaactttt ggacgagttg
    79441 tcaccaaaac gaccatgatt tgtcctgaat agtgaccacg acgcaccaca agattccgaa
    79501 tcaatccaga ctgttccttt tcgtcataag gttttaaatc aaaacgacgg agcaggtctc
    79561 gaagagctac tacgacttgg tcaatgacag gatcctggat aaagaaatct tcaaggggca
    79621 tgaggttgtg cgaattctta cggaaaaatc ctgtttccaa gacaccattc actcgacgaa
    79681 cgggcacctg cgccttattg cgatacttga ctggatgttc cataccaagc gtttcagcaa
    79741 cttctacatc tgcaattcca gcaatcttgt agagactgtc cttgacttgc ttggttttaa
    79801 acttgagctg ttctggataa gaaaggtgtc ctaaatccgc gattcctgaa cgcaggtaag
    79861 ccaaatctag atcttgatta cggtgtggtg actggacaag gtatttttca acttttccaa
    79921 agccaatctt tttattgacc ttgaggacac gcatgagaat tttttcactc ggtaaagcat
    79981 tctctacaaa aaagaccaaa ccatctacct tggcaactcc tgccccttca tgggtcaaat
    80041 caacaatttc aacttctaca atatcatttt tctttaacat tcttttctct ttctattggc
    80101 cgacaaaaaa gacggcaacg ttacggttac catccattat accatgaaat ttcttaagaa
    80161 ccaaaactct tgaagaagtt gacaagggct tgccagaggg agcttaagaa gttaccaccg
    80221 tcctctagcg ccttatccgc atcaaagtta aggttgatat ttttaaaact gtcgccagct
    80281 tgtgatacga tgctttgttt aaggtcattt agggttttag tgaaatctgc attgctgagg
    80341 atatcactct ttgagagatt caaggcaaaa ttgatgatga tattgatctg gtttcctgtt
    80401 atgacctgat caagtttgta attttttaag gtatcttcaa caatcttgcg gatatcttct
    80461 tctgtcagat ttcccttgct ttctttagct ttggcgagtc ctgacttgat atcagctagg
    80521 gcaacgttta atttattagc atcatagcct gatttgtcct tgttttcagc attgatatct
    80581 gacaaagcct ttagctcttc ttgagccaaa tctttattgg cttgcggcac cttggctcca
    80641 ttagcttcta gcgaatagta gatcccagcc aaagcactct cacctgtaac tggaatgggt
    80701 gctgctacag tgattttggc gtgttccaca cccaaagtta cggctgcatt tcggtacata
    80761 tcctgagtta ccttagtgat gttttcaggt gtttcaatct tgacctcaag tggcgatttg
    80821 tcacctagct tttgaatctt ggctgatgaa tacaactgta agctagagtc attggccaca
    80881 ttcatgattt tagaataaac atcaggtgtc atggtcttga gttctttggt atctgttgag
    80941 gcattgtagc ccagtttttt aagagtttga tttttttggt cttcagatag ggaagaacct
    81001 aggacatatt caggttggac ataggtttca tcgataactt tttgaacatc tgttgctgca
    81061 tggacgctat tcatagctgt tactgcccac aagatcgcag cgctagtcag aaagagtttc
    81121 tttctcatag ggaatttcct cctttacttc tttagagtaa tatatctatc ttaaagaaaa
    81181 cttataacaa aaacacctgg tctagccaga tgttgaaaag agagtgaaac atttgataat
    81241 gtaaaggtta agtcgtacct gtctagaata ataatagttt cctccattta catagagttc
    81301 agcaccgtga aaaatggaaa tggggtgaat ataactataa gtctttccag tcgtattacc
    81361 aagcaagggg gcaacagtct cacgagagta ctgtttggct agagccaagg tattttcctt
    81421 gccattttgg gcgataaaat cgatataggc aggtccaaaa ttataggctt gaacagctgt
    81481 ccagatatct acacccttct tctgcgccag atagagattg cctgtcagag tttgaatgcc
    81541 ttgccgaatg ctagaggcat tatcattgat ggtgttggtg gaaccacttg cagactcact
    81601 agactgcata acatcgcctt cttttccttt tgtttcagta taaatcatag caagcacaag
    81661 ctcttcgttt gctggggtgt cttgttcact caatatttct cgcaccatgg gttgataggt
    81721 catgacttgt ttgacatctt gatgaacgcg gtaagcttta tagccagcaa aaaggaagac
    81781 tgctagtaca agcactcttc gaattcgttt aaacattatt tactttggat atcctcgata
    81841 tttttgatta agatagagta ggttccattt tcgttttgga taaactcaac agactcggcg
    81901 tcttgataga cgttattggg aacgatgagc tcaattccat ttgataagga gagtttttgg
    81961 ttttcaaatt tctttaattg gcgactggca tcaatttcat caaattgaac aggttctggt
    82021 acggcttctt tgacttggtc aataaagctc aaacgagccg tcagattgtt gtcaaaaagg
    82081 tcattagcca atttctcagg tgacaattca ttgctttctt ctaggttgtt gaaaatagct
    82141 gatttgacct tggattgaaa ttgaaaatca tctgtgttaa aagattcagc aattctctgg
    82201 gctgtttttt ccagttcctt gatagatttt ttaggagaaa tcttaggagc gacagcaaga
    82261 agattatctg aaaaatagtt caaaaaagtc ccgttgtact tgattcgttt ttcaatcagg
    82321 tgatacttgc gactctgaag attgaccacc aaggcctcgt cagcacccgt tccaaatcca
    82381 ggcaggttat tctgagtcag cttgattgga ttatcaactt ctcctccgag gtgggtcaag
    82441 gtctcccgca gggcaattcg caagaaagcg aaatgttcta caccttcttt agaaaattga
    82501 acaaaaatca agtcattggt cttgagattt tcagaaatgc taaactcctc tttccagaga
    82561 ttagccagcg ttactgatgt ctccaacaaa tcgtctgtaa tatgattgaa gaagggattt
    82621 tcttcttcga aaatcccagt cttggcttca tctgaataca catgttcaat ttttttacgt
    82681 aggtattctt cgatttttgg agtaatattg agaaacttat ctgctaagaa cagctcggta
    82741 tcatccggac tgaactggtg aataatggct ttcttaatat aaatgtccat aaaagtttta
    82801 ttcctcgtat aatgggaagg catctgtcaa ttctttgact gcacttctca cttcttctaa
    82861 tacagcctca ttttctgaat tcttaagggt tttaatgatg agttcagcca ctttgcgact
    82921 ttcttcttca ccaaatccac gtgcagtaat agctgctgct ccgatacgaa tcccacttgt
    82981 cttgaatggt gacaaggttt cgtaagggat tgaattttta tttagggtaa tattgacttc
    83041 atccagcaag ttttgagcaa cttttccgtt ttctacaacc ttagtcacat caacaaggaa
    83101 gagatggttt tcagttccac ctgaaataat acggaaatca gggtcttgca agaagacatc
    83161 tgccatagcc ttgctgttct taattacatt ggcagcatat tccttgaagg ctggatccaa
    83221 aacttctttg aaggaaactg ccttagccgc cacaacatgc tctaaaggac cgccctgaat
    83281 acctgggaaa atagctgaat tgattttttt agcaagttct tcgtcattgg tcaaaatcaa
    83341 accaccacga ggtccacgaa gggttttgtg ggtcgttgtt gtagtgatat gagcgtatgg
    83401 cactgggctt gggtgaagac cagctgcaac caagccagcg atgtgggcca tatcaaccat
    83461 aagcttcgca ccgacagcat ctgcgatttc acggaatttt gaaaagtcaa taatttgaga
    83521 ataggctgaa gcaccagcta caatcagttt tggttttact tcttgggctt gtttcaagat
    83581 agcatcaaag tctaagagtt ccgtttcagg atcaacacta taagaaacaa agttgtaggt
    83641 ttgaccagag aagctaacag gagccccatg agtcaaatga ccacctgatg ccaaatccat
    83701 tcccataacc gtatcacctg gctcaatcaa ggacatgtaa gccgcacagt tagcttggct
    83761 tcctgaatgt ggttggacat tggcaaattt agcaccgaaa atttcttttg cgcgttcaat
    83821 agcaagagtc tctacaacgt ctactacatc agttccacca taataacggc gtcctgggta
    83881 accctcggca tatttatttg tcaagataga cccttgagct gccataacag ccttggaaac
    83941 tacgttttcc gaagcaatta actcgatatt attttgttgg cgttcttctt ctttggcaat
    84001 agcattccag agatcagcat catatgcttt aaaatcatct ttgtcaaaaa tcataggtct
    84061 tctcctttat tgtgtgacta gtccattagt ttgattttac aataagaaaa tcaaactaaa
    84121 agatgcgaat aaaccgtttc tgcattttat cacaagtata gccaactttt tcataaaatg
    84181 catgagcacc cagacgatga ttggcagaat ttaagcggat aaacccataa ccacatcttt
    84241 tggcttcttg ttccaaccct tgtagtaaac ttttaccgat accttgacct tgcgcttgag
    84301 gtgaaactgc taaagctaag atattaaatc ctgctttgga atagagtgat tcgtaaactt
    84361 cagcgtggac atatccaagt aagacatgat tagctgcatc ctcatagcca agtaggaaat
    84421 gatgggaatc ctgagacagt ctagctagtt ggctagccgt ttcctctgga ctaaaagtat
    84481 aacccaaagc ctcttggttg atgtcacata tcgctttcac atctgtttct tgcaaatctc
    84541 ttagcatttc aagcctcctc aaaagaaatc tctggcaacc gagcaagaat atcttctcgt
    84601 ttaattgcgc cttggcgtaa gattttcacc ttgtctccag acaaatccac aatagttgaa
    84661 tcctgtccag ttagaaaagc atcgtcttcc agacccagaa cctcttggtc aaaatccttc
    84721 agaatttgtt caaaggttac accacttgcc tgacctgaga tattggcaga cggcccaatc
    84781 aagggacctg tctctcgaat taaatccagt gtgatagggt gactgggcat ccgaaatcca
    84841 atagttgcaa ggtcagaatt tacccaatag ggaactcggt cattggcttc gagaataatg
    84901 gtcaagggac ctggcaaaaa ggtctctaca agtttttgta gataagttgg ctgattctta
    84961 gaaaagtgca agatatcctc gaaagaggcg atattgagat tgagtgcctt atctctagga
    85021 cgacgtttga gttggtaaac atggtcaact gctttttcat ctaaggcctt ggcaaaaaga
    85081 ccataaacag tctctgtagg tagaacgaca gctccaccat tttccaactc ttgtctaatc
    85141 ctgtccatca tcaaccacaa ccatcctatt ttgaccaaat tggtctttga gtgttcgaac
    85201 ttttttttca ggaagatgtt ttctaaaaag ttcgggaaca ctttgacctt gcttgtatcc
    85261 aatttcaagg taaatcttac caccatcctt gagatagtct tttgcatctt ccgcaattct
    85321 acagtaaata gctaggccat cctcgtctgc aaagagagct agatgaggct ccgaatgcaa
    85381 aacattcaag cctacctctg actcatcttc acgagagata tagggtggat tggatacaat
    85441 tatatcatat ttttcagaaa tttctgcaaa acaatcagat tttttaaaaa atatattaag
    85501 attttgatcg ctagcattct ctgatgcaag ctctaaggcc tcttgagaaa catctgctgc
    85561 tgtcactgac caatctggtc tattttttgc tagagcgaga gcaatagctc cactacctgt
    85621 tccaatatcc agaactgaga gattcgtctc aagattttca gttagaataa gctccactaa
    85681 ctcctctgtt tctggacgag gaatcaaaac ccgttcatcc acctttaaat gcattccata
    85741 aaaatctgcc tgtccaatga tgtactgagc tggcttgtga gctgctagtt gctggtaaat
    85801 atcttctaca aattgttttt cttcctctgt tgtcacctcc tgctggaggg caaaaataaa
    85861 gtctgtaaaa gatagatttt tcagactacg atagacaaaa gagaggcttt ccgcttcctc
    85921 tccttgtctt atcaactctt cttcaaaatt tgaaaataat tgagctaatt tcattatttg
    85981 tttaattctt ctagtttttg tgtttggtca taaagcacca aggcatccac aacttcgtcc
    86041 aatttaccag acaaaatcgt atctagtttt tggagggtca agccgatacg gtggtctgtg
    86101 acacggtttt gagggaagtt ataagttcgg atccgttctg aacggtcacc agtaccgatt
    86161 gtcgacttac gctcagcgtc ttgttcatcc tgagcaatct gagcaaagtg gtcagcgacg
    86221 cgtgcacgga taatcttcat agccttctca cggttcttct gctgggtacg ttcttcctgc
    86281 atctcaacct tgatattggt tggcaagtga acgatacgaa cggcagtcgc aaccttattg
    86341 acgttctgtc caccagcacc tgatgcgtgg taaatatcaa cacgaagatc ttttggatcg
    86401 atatcgtatt ctacttcttc gacttcaggc atgacaagaa ctgtggcagt tgaggtatga
    86461 acacgacctt ggctttctgt cacggggaca cgctgcacac ggtgggcacc tgattcgtac
    86521 ttaagcttag agtatacaga ctgacctgaa accatagcaa ccacttcttt aaacccaccg
    86581 acaccattca tagaggcttc catgacttca aagcgccagc cttgggcttc cgcatacttt
    86641 tggtacatag ttagcaaatc tccagcgaaa agtgccgctt cgtctccacc agctgctcca
    86701 cggatttcaa ggatgatatt cttgtcatcg tttggatcct ttggaaggag caaaattttc
    86761 agtttttctt catattcttc tttttcagcc ttggcatctt tgagttcttg cttggccatt
    86821 tcttccaagt ccgcatctcc gcctgattcc ttaatcatct cttcggcatc gacgatattt
    86881 tgaaggactt gtttatactc acggtaggct attacggtat cacgattgga agcttcttct
    86941 tttgaaagct ccataaaacg cttggtgtct gaaacgacat cagggtcact cagcaattct
    87001 cctagttctt cataacggtc ttctacagct tgtagttgat catagatgtt catttttctt
    87061 cattctcctt attgatttca ggggcaaaat aatgtttacg gcaaaccgag atataggttt
    87121 cattaccacc aatttggatc tgttctccat cgtaaacggg cagtccatcc tgtgttcgca
    87181 acaccatggt cgcctttttc ttgcaatact gacagatggt cttgatttcg tcaatcttgt
    87241 ctgctaaaag caagagatat ttggaacctt cgaacaattc attgcgaaag tcatttttca
    87301 agccaaaagc catgacgggt atgtctaact cgtccacaac acgagctagg tcataaacat
    87361 ggtggcgttt gagaaactgg gcttcatcga ccaacacaca gtaaggtttt tctggtaggc
    87421 ctcggatata gccaaagata tccgttgttt cctcaatcgc aagggcaggg cgtttcatgc
    87481 caattcgact cgacacatag ccaacaccgt cacgcgtatc cagagctgaa gtcataatca
    87541 caacaccttt tccttgctcc tcatagttat aggccacctt gagaatctcg attgtctttc
    87601 cagagttcat ggtcccataa cgataataca actgtgccat gtttcttgct tcacgtccat
    87661 ttctaaattt ttgctacatt ctagtatatc ataattttct taagctttaa acggcaaaat
    87721 gtggtaaaat ggaagaaatc aaaactagtg gaggaagcta ttatgccatt tgtacgcatc
    87781 gatttatttg aaggacgcac gctcgagcaa aagaaagctc ttgctaagga agtaacggaa
    87841 gcagttgtcc gcaacactgg agcccctcaa tctgctgtcc atgtcatcat caacgacatg
    87901 ccagaaggaa cttacttccc acaaggggaa atgcgtacta aataagctag cttaagcaga
    87961 attgcttagg ctttttcaat ctccaagtag cattcattga agaaatatcc taaatttgtt
    88021 acaatttgaa aagaaacttg gagaatttcc aagaaaatag ctattaatta aaggaaacat
    88081 tatgattaca cgtgaatttg ataccatcgc tgctatctct actccactag gtgaaggggc
    88141 tattggtatt gtccgcctga gcggaacaga cagttttgct attgcgcaaa agatttttaa
    88201 aggaaaagac ttgaacaagg ttgccagcca cactctcaac tacggtcaca ttattgatcc
    88261 tctgactggt aaagtcatgg acgaggttat ggttggggct atgaagtctc caaagacctt
    88321 cactcgtgag gatattatcg agattaacac ccacggtggt attgcggtga ccaatgagat
    88381 tctccagcta gctatccgtg aaggagctcg gttggcagaa cctggtgaat ttaccaaacg
    88441 tgccttttta aacggtcgcg tagatttgac acaggccgag gcggtgatgg atatcatccg
    88501 cgccaagaca gacaaggcca tgaacatcgc ggtcaaacaa cttgatggtt ccctttctga
    88561 tcttatcaat aatatccgtc aagaaatcct taacacactt gcccaaattg aggtcaatat
    88621 cgactatcct gagtatgacg atgttgagga agccactact gctgttgtcc gagagaagac
    88681 aatggagttt gagcaattac taaccaagct ccttaggaca gcacgtcgtg gtaaaatcct
    88741 tcgtgaagga atttcaacgg ctatcattgg acgtcccaac gttgggaaat caagccttct
    88801 caacaacctc ttgcgtgagg acaaggctat cgtaaccgat atcgctggga caacacgaga
    88861 tgtcatcgaa gagtacgtca acatcaatgg tgtacctctc aaattgattg atacagctgg
    88921 tattcgtgaa acggatgata tagtggaaca aatcggtgtt gagcgttcga aaaaagccct
    88981 caaggaagcc aacttggttc tactagtgct aaatgccagt gaaccactga ctgcgcaaga
    89041 cagacaactt cttgaaatta gccaagatac caatcgcatt attctactta ataaaaccga
    89101 cctgccagaa acgattgaaa cttcgaaact acctgaagac gttatccgta tttcagtcct
    89161 taaaaaccaa aacatcgaca agattgaaga gcgaatcaac aacctcttct ttgaaaatgc
    89221 tggcttgatt gagcaagatg ctacttactt gtcaaacgcc cgtcacattt ccctgattga
    89281 aaaagcagtt gaaagcctac aagccgttaa tcaaggtctt gagctgggga tgccagttga
    89341 tttgcttcaa gttgacttga ctcgtacttg ggaaatcctc ggagaaatca ctggggatgc
    89401 tgctccagat gaactcatca cccaactctt tagccaattc tgtttaggaa aataagaaaa
    89461 atccatgatc cttcattcgg tcatggattt tattgtcttt attagtaatc tggtcttaag
    89521 acccctgtta cagttgcctt agttgcttcg tagtcgccat ctacgacaac cttgataatg
    89581 cgtttggcat cttcttctgg tgctggaaca agaggtagac gagtgggtcc agcttcaaat
    89641 cccatatagt taagaattgc cttaactgga gcaggacttg gataagagaa gagagcatta
    89701 accttaggaa tgaatttacg ctgaattgct gcggctttct tcatatcgct ttctgcaatg
    89761 gcagtaaaca tctcgtgcat ttcatcccca tttgtatgag aggcaacaga aataacccca
    89821 tccgccccaa ggttcatggc atggaaagca tctccatcct cacctgtata aatcaagaac
    89881 tcttcaggct tgtgctcaat caagtaagcc atattagcca agctagtaca ttctttgaca
    89941 ccgataatat ttggatggtc agccaagcga agcatggttt ctggagtcaa ttcgacaact
    90001 acacgccctg gaatgttata gataataatt ggtaggtcag aagcatctgc aatagtctta
    90061 aagtgctgat acatcccttc ttgagaaggt ttgttgtagt aaggaacaat agcaagccca
    90121 gctgcgaaac caccaaattc cgctacttct ttgacaaact caatagagtc acgcgtatca
    90181 ttagtaccta cacccgcaat caaaggaacg cgtccattga caaccttttg tacagccgca
    90241 aacaactcca actcctcatc gtgggtcaaa gttggactct cagcagtcgt tcctgcgaga
    90301 agaattccat ccgtatgatg ggccaataaa tgctcaatca aggctggaat agcatcaaag
    90361 ttaatagaac catcctcatg aaagggggta ataaaggctg taatgatttt acattctttt
    90421 aaatcttgat aagacatgaa aacacctctc tatttcaaag aaggagttca tctgaactcc
    90481 taaacgatat gactatttta attcaaattt caattcggct gttggacgaa ccaatccacg
    90541 ttcatgaaga gtttcagcaa tctgaactga gttccaagca gcacctttga gaaggttatc
    90601 tgaaacaacc cacatgtgaa ttcctttttc tgcatccaag tctttacgga tacgaccaac
    90661 aaaggtatca cgcgaaccaa ctgcattgat agcttgagga tagatttgat gagctacatc
    90721 atcttcaaga acagcacctg ggaaggctgc gatagctgct tttacttctt cgattggagc
    90781 cacttctttt gtttcgatat aaacagactc agagtgagct gacaagactg gaatacgcac
    90841 acatgttgca gatactgcaa tgctatcatc ttccataatt ttcttagttt ccttggtcat
    90901 cttcatctct tcgtaagtgt aatcattgtc agtgaagaca tcgatttgtg gaagagcatt
    90961 gaaggcgata ggataatgtt tcttgtcacc gcctgaaggt aagatttccg catgcaaatc
    91021 acgtggtttc actccatcat tcaagacctc acgaagttca cgttgtgtct caagaattgc
    91081 tcccatacca gcacctgaaa cggcttgata agttgaaaca atgatacggt ccaagcccca
    91141 tttttggcga accggctcaa gagccaccat catttggatt gttgaacagt tagggcaggc
    91201 aatgattccg ttgtgggcat caagtgcatg agcattgacc tctggaacaa ccaaaggaac
    91261 atctggattt tgacggaaat aagatgtatt atccactact accacgccag cttttactgc
    91321 gtatggtgca tacttagctg atgtcgaacc acctgctgaa aagagagcaa tatcaactcc
    91381 ttcaaaagct gtttcagtcg tttcttcaat cgtaatatct tgatctttaa atttcaatga
    91441 cttacctgct gaacgtgcag aagcaaggta acggatttta tcgattggaa gtgttgattt
    91501 ttccaacatt tttatcatct gagcaccgac agcacctgtc gcgccgacta cagcaactgt
    91561 atatcccata aataacctct ttcggaattt tctaaaaatt tctataatag aagtattata
    91621 ctactttttc catgaattgc aaagcttttt catcattttt tggaaaataa aaatccccaa
    91681 tcgctagact agggattaag aggcatcttc atgtgatgag caggttcaca caactcatca
    91741 aggtccgctc ctgcgttatg acctccttat gctcaatagt agcccgaaga ctacctatcg
    91801 actcatcgca tattctatat tactagagat agttgatttt gtcaataaga aattttttcg
    91861 atcgagtata acaaaaaact ctcgtattca agagtttccc tatacatatc atgctaattg
    91921 ccgggattga accggcgacc tcatccttac catggatgcg ctctgccaac tgagctaaat
    91981 cagcttactt aagaagtata ctatattcag aaaaacttgt caagtttcct tagaaatttt
    92041 ccataggaaa aagccaggta agaactacct agcttatctt cttctattta cttaaatcaa
    92101 ttcgacgacc aattttacca ataataatcg ccccaataat caatgaagca aattcaccga
    92161 ttcctgttgt aaaccaagta aggaagaatg gtaattctgc tacaatattt aactctgcag
    92221 cgatagtaaa catggaaatt gaaaagagga ttgaaaagaa gaaatgatct tttcgaatca
    92281 atccgttaaa gaggtaatcc ttgctatatt ttgcaaaaag ccaaacacct aaactgagga
    92341 atactaaggt tgaaccacca ccaacaaaga catctagcag tccgaagcta aagaaattag
    92401 caatcataca accgatggta actccgatga tgtacttagg attgtaaaaa gccataaagt
    92461 tcatcatttc tgaaatacga aactgataag caccatagct gatggcattt aggggcggtg
    92521 tgacagtcaa aacgacgtag atagcagcga cgattgcaat atctgcaaca tcacgaatag
    92581 ttaatttttt catcttttct cctttggcgg ttgcccgcgt gtaatatgct tggtgaaaga
    92641 agctaagcac caagggttgc tttattcaac cctactagta tagcacaata gcctgcttta
    92701 tgctatactt aacacatgaa aattcctatt caaaaatttt ttaacaatga aatcttagcc
    92761 tatctctttt ttggtatagt gactactctt gttgctatac tattacgatt agtcatttat
    92821 cagctaagtc atcaagaact ccttgctacg gccttggcaa atattatcgg tattttattt
    92881 gcctttatca caaatgatac aattgtattt aagcaaaaaa agaaaaatag acttatccgt
    92941 ttagtgaaat tttctcttgc tcgcctttct acttttctgt tagacttgtt tttaactttt
    93001 ctctttgtaa cccaatttcc tcacatcata gggcaattcg taactgaaaa cattgataag
    93061 ataaatgcta ttgaaacaat aattgcacaa atattcatta ttatcatcaa ttatatcttg
    93121 agcaaggtct atatttttag aaaataatgc tccatttatg agccttttaa ttgccttcta
    93181 taatgattta ggatacaatg aaacacgaaa cattgaaagg aaaacagtat gttaaaaaat
    93241 ctaaaatcgt tcttgcttcg aggaaatgtt attgaccttg ctgtcggtgt tgtaattgcc
    93301 tctgcttttg gtgctatcgt tacttcactt gtaaacgaca ttatcactcc tcttatttta
    93361 aatcccgctt tgaaagctgc taaagttgaa cgtatcgctc aactttcttg gcatggagtc
    93421 ggctatggta acttcttaag tgctattatc aattttatct ttgtgggtac cgccctcttc
    93481 tttattatca agggcattga aaaagcacag aaactgactg gcataaagga agaaaaaact
    93541 gccgaaaaaa aaccaaccga attggaagtc cttcaagaaa taaaagctct ccttgagaaa
    93601 aaataatcga ttaaaaggat ctagcgcaaa gctaaatcct tttttcttta ctctttgggt
    93661 aacttgcctg ctttttcaag catttttttg ataagataag gcatcttaac attctcccgc
    93721 ccttttttct caatcagttt tttcacaaat tctggcattt gtaaatcttc agattcagcc
    93781 aaaatgtttt ttgtctcgtc tgaaggaact aactcatcaa aggtctcttc ttctgggaga
    93841 aattccttaa actcttgatt ttcattgact ctaactgtat tgaccaaagc atcaatcaaa
    93901 cgagaatctg tatttggcat tggtggacga tggtagttta ccccaaattc ctgacataaa
    93961 tcataacatt ccacatcatt gtcaaacaag acctcaatat gctcactgat gaaactaata
    94021 ggtacaaaaa tataatggtc tggatgttct gtctgttctc tgagatactc caaaacatct
    94081 ggtttaatcc atggaatacc aatatcactc tcactctgcc aagtgttagt atattgtttt
    94141 gaactcaagc ccagtttttc agcgactagc ttgctatttt cgaaaatttg gtctatataa
    94201 ggatcaccaa agtccaaggc aaaaataggc acactatggg ctgaaaagat gactttaaag
    94261 ctgtcttgct ttacttcttc ttttaaaatc ttagcaattt catctgccca atagtttaag
    94321 agcgcttctt cctgatacca gtccttaatg accaaaaatt gaatttgttt gctttctaaa
    94381 aatttttcat agcccatgac agagtagaaa gaataatggg gctccaaaat caagcaaata
    94441 cactgttcaa ttccgtctgc ttccatttga ccgatcacat ctggaataaa gggactggaa
    94501 aacttattag caaagtagac actgtattca ttccccagcc tagcttctac caaggcaacc
    94561 tcttgacggg taattttttg cagaggcgtg cctccaattc gtacataatt atcatagaga
    94621 gtctgaatct cgtggtcttg gggtctcacc ccacgacgaa tatttgtgaa aaaatcagct
    94681 acaccttcaa aggtaatctc ttctggtgaa ccgaaggtca tcattaaaat tgcttttttc
    94741 atgactgctt ccttgtgatg tttttatcaa gtttatttta tcattaattc atcgataagt
    94801 aaacgctagc atagggacat tctcaatctt ctgtcttttg tttttctctt ctttctatga
    94861 tacaatggaa aaaataaatt caaaaggagt ttttttatga cttatccaaa tctcttggac
    94921 cgcttcttaa cctacgttaa ggtcaacacg cgctctgatg aacactctac tactactcca
    94981 agtacacaga gtcaggttga cttcgcaaca aatgtcctaa ttcctgaaat gaaacgtgtt
    95041 ggactgcaaa atgtttacta tctaccgaat ggttttgcta ttggaacctt gccagccaac
    95101 gatccgtctt taacacgtaa gattggtttt atatcgcaca tggatactgc tgattttaat
    95161 gctgaaggag tcaatccaca ggtaattgaa aactacgatg gtggtgtgat tgaactaggg
    95221 aattctggtt tcaaactcga tccagctgac ttcaagagtc ttgaaaaata tccaggacaa
    95281 acgctcatca caacagatgg aacaaccttg ctaggtgctg atgacaagtc aggaattgct
    95341 gaaattatga cagccattga atatctaact gctcatcctg aaattaagca ctgtgagatt
    95401 cgtgttggtt ttggtccaga tgaagaaatc ggtgttggtg ccaataaatt tgatgcagaa
    95461 gattttgatg tggattttgc ctacactgtt gatggtggtc cactaggtga acttcagtac
    95521 gagactttct cagccgctgg tgctgaattg catttccaag gccgtaatgt ccaccctggt
    95581 actgccaaag ggcagatggt caatgccctt cagctagcaa ttgattttca taatcaactt
    95641 ccagaaaatg accgacctga gttaactgaa ggttaccaag gtttttacca tctaatggat
    95701 gtgacaggta gtgttgagga ggcgcgtgca agctacatca ttcgtgattt tgaaaaagat
    95761 gcctttgaag cgcgtaaagc atccatgcaa tctatcgctg ataagatgaa tgaagaactt
    95821 gggagcgacc gtgtcactct caacttgaca gaccagtact acaatatgaa agaagtcatt
    95881 gaaaaagata tgactccaat taccattgct aaagccgtta tggaagatct aggtatcacg
    95941 cctattatcg aatcaatccg gggtggaaca gacggctcta agatttcctt tatgggaatc
    96001 ccaactccga atatctttgc aggtggcgaa aatatgcacg gacgttttga atacgttagc
    96061 cttcagacta tggaacgtgc agttgatacc atcattggca tcgtagctta taaaggctaa
    96121 aaagacgagg tggctcagct acttcgcctt tctttttatt ctactggttt ttcttgattt
    96181 ccagtagttg tagaagattc tgttgtttca ttttctgaag ttgattcagc aggtttagaa
    96241 tctcttgtat tgcttggttt gttttcgtcg ctagcagttt caatgttaga ttctgcagtt
    96301 gcgtttggtt ggttctcagc actggtgtta tcaccatttg cttcagcatt tcttgctgga
    96361 cttgtttctt cacttgcgct agcttttgac tggatttgat gattcaaaac tagaatagct
    96421 tttgtcggtt caagtaaagc tgttttgtct ttactcttag cagaaagttg atctaataat
    96481 gcatccacct tatcaaagtc cgcatcagat ccattattac tttctaaata agagtgaagc
    96541 gacatgagaa tatcgtagag tttttgatag agtacaagtg tctgaggatc ttgctcagca
    96601 ttttcctttt cttgttgaag ggcgctagcg atacgagtca aaacatcttt tacctgactg
    96661 tttacttcat ccaagtctgc atcagccttg tttgtggcag cttttagatt ttctacttct
    96721 tctgccaagg attgtctgat tccttcttca tggatttgtt ccaagagttg atttgccttg
    96781 ctcaaaagac tttctacttc ttccttgcta tctgtcgcag attattggtt gccatctacc
    96841 atgtactcct aaaacaggag agttataatc caagattaca aggccttaca gaaataagaa
    96901 atccagataa gacaatgttc gtccaagacg ctattcgctt cgcacagcag cacggattca
    96961 atatgcttta attttaaagt ttaggtgtca agacctcttt ttagtgtgcc caaaatttag
    97021 agaagtaatc aatcaactaa cttttatttt tttcaaactt tcagtaaact gacctaaagc
    97081 taactcaatc tgtctttgtt cgataggctt gtctttgtag atgcttctgc tatcagctag
    97141 aagttgatct acttttgcca agactgcctt ctcataaaaa gttccaggtt gatagttgga
    97201 ttgcagggat ggaatcttgt ttttcaaagc cgcttcatat cccttagttt gaaccttgat
    97261 gtagtgattg tggtcgccac gaggaatcac aaaaccttct gaatcttcac ttataattcg
    97321 attggcatca aaaccatgac catcttcttc ctcatggtgg acatgtagtg acggattact
    97381 taatacagaa ctagaagaac ttcctacctt ttccgtgtta gagtgtgatg ggggattgtt
    97441 aagagatgac ttaggaatat agtgatagtg accccatgtc ttactatata agcatcacct
    97501 gtatctctga caatatcatt agggttaaag acatatgtgg ctgctaattc acctgccgac
    97561 aagtcactct caggaatgaa atgatagtga ccaccatgtg gtactatagt aggttgaaat
    97621 agaatatgag caaattgata aggggatttt aaagtaattt ctaacaatga tttagaaact
    97681 atgatgtgct attctaaatt caactcacta tatataacca tcatcggtag tataacgtcc
    97741 ctgtaatttt gctacagata cttctgcact agctccttta tcgtctttac catgttcttg
    97801 tttttggcga ttgatttcat cttttgttcg tacattttct gcatgagctt gatctttaag
    97861 gtaaacataa tactttccat ctaccttaat aatatatcct cccttaacct aactgacaat
    97921 atcttgatct ttcggctgat agttgggggc tttcattaat ggctcttcac taaagagcgc
    97981 atcaaaagga actttaccat tatagcagtg ataatgatcg ccatgagaag ttacataacc
    98041 ttgacctgta atcttaataa caatttgttt tgcttgaatt ccttcttttt gactaaccta
    98101 gtctggagtc aaattttcag tcttcttagt gtctttatta ctgtttacat atgaaacacg
    98161 atttttatct gtattggcct gttagctatg ttggttcaga gcataaacac acagacttaa
    98221 ggaaaggata acaacagatc cagctgctat atatttcttt ttaaatttca taattacctc
    98281 atttctataa ttatttatat gatgtcttca ttattaaatg attatagaaa ttaattaacc
    98341 aattaattaa ctagtaaata ttccacctct ttttaagttg tatgtcaaga aattttatat
    98401 attaataata aaatgaaatt ctcccaaagt cagagtttta tttctaactt ttgagagaac
    98461 ttcatttttg attcagactt tttctactgc tattccttac gctatgagat cagataaatt
    98521 cttttttatc acttctccac ttggcaatct taattcaatc gttccatcca tattgaatat
    98581 aacactatct aagcctaatc cgtaactagc tgtaaatttt tctaattttt cttgtacagg
    98641 atctactgct ggagcttcct ctaatgctga atctaacata gggtcactcc ccacattccc
    98701 ttctggattc aacattccat tatccgttga gttttctggt tttacaggtt tttcgtttgg
    98761 tgcctctggt aaagaatctg ctggtttatt ttctgttggt tggttctcaa ctgttccagt
    98821 agatactttt ccattttcag atggtttatt ttcaccattt ccttgaggtg cttctcctgt
    98881 aaaatctgcc atattctttt taatgacttc tcccgatggt aaatataatt caattgttcc
    98941 gtccatatta aacaagacat tttctagctt catcccataa ctttcagcaa attttgctac
    99001 tttttcttgt acaggatcca ctgtaggaac ttcttctaac gttgaattac tagtactatt
    99061 cccagtttca gaaagttttt ctttttctac cttctcacta gtctttggtt cttctacctt
    99121 ttcatcaagt tttgagtttt cttgtgcttt attcctttta aattgtggta gaatacttgg
    99181 tttatcagtt tgattttctt tttccaagat aggtacttcc acaatataag tcgattgatt
    99241 gtccaaataa gcatttgcca tgaaggttac aggaatttta tttccggccg ttctggttgt
    99301 tccttggttt aatttcggaa tcggtaattt gatttcacca actttatagt tattttctaa
    99361 ataagcattt ccatgaaatt catcaaacac tctgactaaa gcatcagttc ctttaggcac
    99421 tgcaaattga gggttcactc ttaaataagt atcccctgca tggaaaggat agaaaatcgt
    99481 ttgactggcc attttgtaag ctaaagaggt tggaactgta aatgtaccat cataacttac
    99541 ttctggataa tcttttgaag cgatagtata cttaaatgtt tgtcctggta aataaggttg
    99601 atctaattca aagtttgcaa tattccctac tccttctcca aatactttac cagatacttt
    99661 ctccaatact tttccatctg gtgttattaa ttttactagc atattgatac ctaatttttt
    99721 ctccaattca ggcggaaaac taaaagaaac gcgtttttga ccattggcta gagtaaagtt
    99781 ttgattatta aacgtactat tttttaacaa attaacaaca ttcgttaatt cttctccagt
    99841 ataaacttta ttcccttctt ttttagcaac tccttcttcg ggtttaaaca gttcatagtt
    99901 actgtgagaa tgaccaattc caaccggttt atgttcatca atcggatctg catgatggtg
    99961 atctccatgc ggataaataa tcgcattttt ttctttattc acgacaatac tttcacgttt
   100021 gacaccatat tgtttcataa tgccagcaat tttttcttcg atttttttat ctaaatcttt
   100081 catttctttg gcattacttg gataatcctg ttcatgagat gacaaagaat ctaatccatt
   100141 atgactagtt ttaacttcct ctaaatgttt ttgcgcagcc ttaatttgct cttctgtcaa
   100201 gtccttcttg aagaaataat gattgtggtc tccgtgactc atgacaaaac ctgattcatc
   100261 ttcagcgata atacgattag catcaaatcc gtatccatct tcttcatgtt tctcatgtga
   100321 agttcctgga ttgattggaa gagatggaga aggtgttgaa gaatagctta actgactcgg
   100381 ttgcatattt tttccagcca gatgtgcttt agctgctgct aattcactag cagataaatc
   100441 gcttttggga atgtagtgat agtgacctcc atgaggaacg atataagcat tacccgtatc
   100501 ttcgataata tcagctggat taaagacata accatcattt gtcgtatatc gtccctgaga
   100561 ccttgctaca gcaacattag agttaacctt ctcattatct ttgacatgtt cttgtttttg
   100621 acgattgatt tcatctttag ttcgaacatt atcagcatga gctgcatctt tcaggtagac
   100681 ataatatttt ccatcgacct tgatgatata accacccttg acttcattga caatatcagc
   100741 gtctttaagt tgatagtttg gatccttcat caagagttct tcactaaaga gggcatcata
   100801 aggaactttc ccattatagt aatgatagtg atcaccgtgt gacgttacat agccctgatc
   100861 tgtaattttg attacaattt gctcagcctg aattccttct ttctggctaa cctggtctgg
   100921 tgtcaagttt tcacttttct gacttgactg gctgccatcc acataagaga cacgattatt
   100981 gtccttattt tcctgcgaac gatgctggtt tagtgcatag gcacatagac tcaaggatac
   101041 gataacagct gatccagctg ctatatattt tttactaaat ttcataaatc cctcatttca
   101101 ataaatgatg aagttttttc tcaacttctt ttactttatt aaatagtttt ctaaaccggt
   101161 tatttaacca tttaattaac cagtaaatag tttactattt aaaattactt ttgtcaagtt
   101221 tctgttacgt ttttctaaaa aagagaagta acacgaaagg ttacttctcc ataaaatatg
   101281 ctccattcat tttactactg tatcggagcc ggttgacttt tttttaacaa agccaagaga
   101341 ctatctactt ctgctgaaat agtgttatta tctttcgttc cgagaagaag actacttttt
   101401 agaccagtca atgtctccat agcattttgt ctaatactag gatctgttac tttttctagc
   101461 aaggcctccg catctgctat cttagcgtta ataacagaat tctctacttg aggaatttca
   101521 gcctcatctg tggtatcttc agcttcttcc tctgtctctt ccgtatcagt gcttggttta
   101581 taaagattat ctgctgaagg atttaaacca gcgtgattct ctttttcatc agattcaggg
   101641 tgagttggct cacttacttc atcatgttcc ttatcttcat caggtttact gtcttggtct
   101701 gccttatttt tacgaacatg gtcgctagcg ttaccaaaac cattatctga atgcggacgt
   101761 tcgtttggat gttcgacata gtacttgaca gtcgccaaaa gatcctcaag agtatacccc
   101821 ttaggtgcct cataaaggcc ttcgtcaaac cactcaaatt tgatgttatg gtaatggtca
   101881 taatgaggta tgattaaact accgtttttg acttctacag tatattgaag attgtaaggc
   101941 atacgatcaa gtggcacctt cttagctgct ttcacgcggt tgtagatagc ttctgctcct
   102001 tttgcctcag tatttcctga atcctgatgg tctgtcgaag gaggggtcaa acctttctct
   102061 ttagcataag cctgggctgc cgctctctca gcttcagaca aactatcttt tttaatccag
   102121 tggctatggg tcatatgtgg agttacatag gcatccccct catcactggt tatatcacga
   102181 ggatcaaaga tataaccgtc ttctgttgtg tacttgcctg ccaacttggc tacttgaatc
   102241 tcatcatcag tgtaggtaat ttgcgcattt ggttttccta aacgttctgg atgacgaatc
   102301 ggagctaaga aggcaagaat atcatccact aacttgactt tatcacttgg gacatccttg
   102361 agtcgttcca acaggttatc caaagcctca aaatcaactt gtcgaccttt attatcaagt
   102421 aaatcttggt gaattcttgc tagtaagtca taagccttat tgtaaaattc tcgatcacta
   102481 gatgggaggt cagttttctt agctcctagc ttatgagata aactttcctg cttggccagt
   102541 ttgctatcaa tgcctgctgc tgtttctgct gaaagattct tggctgggat ataacgagaa
   102601 actccattct tctcaaagac ataaccatcg cctacttttc gaacagcttc tttgaccaat
   102661 ttctcatcaa ttggattgct tggagctggt tgaggatttg gtgcagattg cggacttgga
   102721 ctaggttctg gagtcgattg tggacttggt tgttctggtc ttgaatctgg tacccaatgg
   102781 tttgaacgat aacgaagggg aataatacga gcaattcgtt cttccaattc agacatttga
   102841 gagtaaggga taaagtggta atggttacca tgagggacag ctacacctct ggcggttcga
   102901 cttgtgattt gcgctgggtc gaaaataagg c
//
LOCUS       DBEJZV010000003        90023 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.03, whole genome shotgun sequence.
ACCESSION   DBEJZV010000003 DBEJZV010000000
VERSION     DBEJZV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 90023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90023
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.03"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..195
                     /locus_tag="ACL3S0_000218"
     CDS             <1..195
                     /locus_tag="ACL3S0_000218"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311201.1"
                     /translation="NSPCCGWILFSLLILFETLFKPRQLHLAVYVLLTSSVLSTTSKR
                     CFEQPAASFLVCSLIFIEYY"
     gene            253..909
                     /locus_tag="ACL3S0_000219"
     CDS             253..909
                     /locus_tag="ACL3S0_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGR1311202.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            899..1222
                     /locus_tag="ACL3S0_000220"
     CDS             899..1222
                     /locus_tag="ACL3S0_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGR1311203.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMILFILVKHKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1326..2156
                     /locus_tag="ACL3S0_000221"
     CDS             1326..2156
                     /locus_tag="ACL3S0_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1311204.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2310..3164
                     /locus_tag="ACL3S0_000222"
     CDS             2310..3164
                     /locus_tag="ACL3S0_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR1311205.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3264..4637
                     /locus_tag="ACL3S0_000223"
     CDS             3264..4637
                     /locus_tag="ACL3S0_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGR1311206.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4630..5691
                     /locus_tag="ACL3S0_000224"
     CDS             4630..5691
                     /locus_tag="ACL3S0_000224"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGR1311207.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5693..6385
                     /locus_tag="ACL3S0_000225"
     CDS             5693..6385
                     /locus_tag="ACL3S0_000225"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGR1311208.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6415..6984)
                     /locus_tag="ACL3S0_000226"
     CDS             complement(6415..6984)
                     /locus_tag="ACL3S0_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR1311209.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7119..7733
                     /locus_tag="ACL3S0_000227"
     CDS             7119..7733
                     /locus_tag="ACL3S0_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR1311210.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLVGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7711..9381
                     /locus_tag="ACL3S0_000228"
     CDS             7711..9381
                     /locus_tag="ACL3S0_000228"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR1311211.1"
                     /translation="MKNWRQNRMKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDRESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9393..10679
                     /locus_tag="ACL3S0_000229"
     CDS             9393..10679
                     /locus_tag="ACL3S0_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR1311212.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10731..11264
                     /locus_tag="ACL3S0_000230"
     CDS             10731..11264
                     /locus_tag="ACL3S0_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311213.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11342..11812
                     /gene="nrdI"
                     /locus_tag="ACL3S0_000231"
     CDS             11342..11812
                     /gene="nrdI"
                     /locus_tag="ACL3S0_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGR1311214.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12105..13367)
                     /locus_tag="ACL3S0_000232"
     CDS             complement(12105..13367)
                     /locus_tag="ACL3S0_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGR1311215.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDAVFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13677..14135)
                     /locus_tag="ACL3S0_000233"
     CDS             complement(13677..14135)
                     /locus_tag="ACL3S0_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGR1311216.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14132..14572)
                     /locus_tag="ACL3S0_000234"
     CDS             complement(14132..14572)
                     /locus_tag="ACL3S0_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR1311217.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14928..16877
                     /gene="mutL"
                     /locus_tag="ACL3S0_000235"
     CDS             14928..16877
                     /gene="mutL"
                     /locus_tag="ACL3S0_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGR1311218.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17202..17669)
                     /gene="ribE"
                     /locus_tag="ACL3S0_000236"
     CDS             complement(17202..17669)
                     /gene="ribE"
                     /locus_tag="ACL3S0_000236"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGR1311219.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17670..18875)
                     /locus_tag="ACL3S0_000237"
     CDS             complement(17670..18875)
                     /locus_tag="ACL3S0_000237"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGR1311220.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18895..19530)
                     /gene="ribE"
                     /locus_tag="ACL3S0_000238"
     CDS             complement(18895..19530)
                     /gene="ribE"
                     /locus_tag="ACL3S0_000238"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGR1311221.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19515..20615)
                     /gene="ribD"
                     /locus_tag="ACL3S0_000239"
     CDS             complement(19515..20615)
                     /gene="ribD"
                     /locus_tag="ACL3S0_000239"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGR1311222.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVQQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20749..20863)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            21020..21613
                     /gene="ruvA"
                     /locus_tag="ACL3S0_000240"
     CDS             21020..21613
                     /gene="ruvA"
                     /locus_tag="ACL3S0_000240"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGR1311223.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21623..22186
                     /locus_tag="ACL3S0_000241"
     CDS             21623..22186
                     /locus_tag="ACL3S0_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGR1311224.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQVLFELLCMETYQA
                     GLSWETVLNKRQAFREVFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     VFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22183..22860
                     /locus_tag="ACL3S0_000242"
     CDS             22183..22860
                     /locus_tag="ACL3S0_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR1311225.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(23015..24046)
                     /locus_tag="ACL3S0_000243"
     CDS             complement(23015..24046)
                     /locus_tag="ACL3S0_000243"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGR1311226.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCPKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(24301..24984)
                     /locus_tag="ACL3S0_000244"
     CDS             complement(24301..24984)
                     /locus_tag="ACL3S0_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGR1311227.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24996..25940)
                     /locus_tag="ACL3S0_000245"
     CDS             complement(24996..25940)
                     /locus_tag="ACL3S0_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR1311228.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            26072..28903
                     /gene="uvrA"
                     /locus_tag="ACL3S0_000246"
     CDS             26072..28903
                     /gene="uvrA"
                     /locus_tag="ACL3S0_000246"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGR1311229.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKADVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28896..29957
                     /locus_tag="ACL3S0_000247"
     CDS             28896..29957
                     /locus_tag="ACL3S0_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR1311230.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASSLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            30089..30487
                     /gene="spx"
                     /locus_tag="ACL3S0_000248"
     CDS             30089..30487
                     /gene="spx"
                     /locus_tag="ACL3S0_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGR1311231.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30553..31122
                     /locus_tag="ACL3S0_000249"
     CDS             30553..31122
                     /locus_tag="ACL3S0_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGR1311232.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKIYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31209..31475
                     /locus_tag="ACL3S0_000250"
     CDS             31209..31475
                     /locus_tag="ACL3S0_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGR1311233.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31479..31898
                     /gene="ruvX"
                     /locus_tag="ACL3S0_000251"
     CDS             31479..31898
                     /gene="ruvX"
                     /locus_tag="ACL3S0_000251"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGR1311234.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31914..32219
                     /locus_tag="ACL3S0_000252"
     CDS             31914..32219
                     /locus_tag="ACL3S0_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGR1311235.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32474..33724
                     /locus_tag="ACL3S0_000253"
     CDS             32474..33724
                     /locus_tag="ACL3S0_000253"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR1311236.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33808..34266
                     /locus_tag="ACL3S0_000254"
     CDS             33808..34266
                     /locus_tag="ACL3S0_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGR1311237.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPVAQQQVQQPAQQ
                     NTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESD
                     GDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            34412..35944
                     /gene="cls"
                     /locus_tag="ACL3S0_000255"
     CDS             34412..35944
                     /gene="cls"
                     /locus_tag="ACL3S0_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGR1311238.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            36202..37740
                     /locus_tag="ACL3S0_000256"
     CDS             36202..37740
                     /locus_tag="ACL3S0_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGR1311239.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37860..40067
                     /gene="nrdD"
                     /locus_tag="ACL3S0_000257"
     CDS             37860..40067
                     /gene="nrdD"
                     /locus_tag="ACL3S0_000257"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGR1311240.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40079..40219
                     /locus_tag="ACL3S0_000258"
     CDS             40079..40219
                     /locus_tag="ACL3S0_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311241.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKYSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40263..40769
                     /locus_tag="ACL3S0_000259"
     CDS             40263..40769
                     /locus_tag="ACL3S0_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311242.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            40762..41352
                     /gene="nrdG"
                     /locus_tag="ACL3S0_000260"
     CDS             40762..41352
                     /gene="nrdG"
                     /locus_tag="ACL3S0_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGR1311243.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41349..41966
                     /locus_tag="ACL3S0_000261"
     CDS             41349..41966
                     /locus_tag="ACL3S0_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR1311244.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTLAQELSQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAYELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRFARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42221..42529
                     /gene="rpsJ"
                     /locus_tag="ACL3S0_000262"
     CDS             42221..42529
                     /gene="rpsJ"
                     /locus_tag="ACL3S0_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGR1311245.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42745..43371
                     /gene="rplC"
                     /locus_tag="ACL3S0_000263"
     CDS             42745..43371
                     /gene="rplC"
                     /locus_tag="ACL3S0_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGR1311246.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43396..44019
                     /gene="rplD"
                     /locus_tag="ACL3S0_000264"
     CDS             43396..44019
                     /gene="rplD"
                     /locus_tag="ACL3S0_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGR1311247.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            44019..44315
                     /locus_tag="ACL3S0_000265"
     CDS             44019..44315
                     /locus_tag="ACL3S0_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGR1311248.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44333..45166
                     /gene="rplB"
                     /locus_tag="ACL3S0_000266"
     CDS             44333..45166
                     /gene="rplB"
                     /locus_tag="ACL3S0_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGR1311249.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45270..45551
                     /gene="rpsS"
                     /locus_tag="ACL3S0_000267"
     CDS             45270..45551
                     /gene="rpsS"
                     /locus_tag="ACL3S0_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGR1311250.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45563..45907
                     /gene="rplV"
                     /locus_tag="ACL3S0_000268"
     CDS             45563..45907
                     /gene="rplV"
                     /locus_tag="ACL3S0_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGR1311251.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45920..46573
                     /gene="rpsC"
                     /locus_tag="ACL3S0_000269"
     CDS             45920..46573
                     /gene="rpsC"
                     /locus_tag="ACL3S0_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGR1311252.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46577..46990
                     /gene="rplP"
                     /locus_tag="ACL3S0_000270"
     CDS             46577..46990
                     /gene="rplP"
                     /locus_tag="ACL3S0_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGR1311253.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            47000..47206
                     /gene="rpmC"
                     /locus_tag="ACL3S0_000271"
     CDS             47000..47206
                     /gene="rpmC"
                     /locus_tag="ACL3S0_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGR1311254.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47231..47491
                     /gene="rpsQ"
                     /locus_tag="ACL3S0_000272"
     CDS             47231..47491
                     /gene="rpsQ"
                     /locus_tag="ACL3S0_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGR1311255.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47517..47885
                     /gene="rplN"
                     /locus_tag="ACL3S0_000273"
     CDS             47517..47885
                     /gene="rplN"
                     /locus_tag="ACL3S0_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGR1311256.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47963..48268
                     /gene="rplX"
                     /locus_tag="ACL3S0_000274"
     CDS             47963..48268
                     /gene="rplX"
                     /locus_tag="ACL3S0_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGR1311257.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48292..48834
                     /gene="rplE"
                     /locus_tag="ACL3S0_000275"
     CDS             48292..48834
                     /gene="rplE"
                     /locus_tag="ACL3S0_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGR1311258.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48852..49121
                     /gene="rpsN"
                     /locus_tag="ACL3S0_000276"
     CDS             48852..49121
                     /gene="rpsN"
                     /locus_tag="ACL3S0_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGR1311259.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49406..49804
                     /gene="rpsH"
                     /locus_tag="ACL3S0_000277"
     CDS             49406..49804
                     /gene="rpsH"
                     /locus_tag="ACL3S0_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGR1311260.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGSNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            49996..50532
                     /gene="rplF"
                     /locus_tag="ACL3S0_000278"
     CDS             49996..50532
                     /gene="rplF"
                     /locus_tag="ACL3S0_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGR1311261.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50616..50972
                     /gene="rplR"
                     /locus_tag="ACL3S0_000279"
     CDS             50616..50972
                     /gene="rplR"
                     /locus_tag="ACL3S0_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGR1311262.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            50990..51484
                     /gene="rpsE"
                     /locus_tag="ACL3S0_000280"
     CDS             50990..51484
                     /gene="rpsE"
                     /locus_tag="ACL3S0_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGR1311263.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51498..51680
                     /gene="rpmD"
                     /locus_tag="ACL3S0_000281"
     CDS             51498..51680
                     /gene="rpmD"
                     /locus_tag="ACL3S0_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGR1311264.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            51825..52265
                     /gene="rplO"
                     /locus_tag="ACL3S0_000282"
     CDS             51825..52265
                     /gene="rplO"
                     /locus_tag="ACL3S0_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGR1311265.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52278..53588
                     /gene="secY"
                     /locus_tag="ACL3S0_000283"
     CDS             52278..53588
                     /gene="secY"
                     /locus_tag="ACL3S0_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGR1311266.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53739..54377
                     /locus_tag="ACL3S0_000284"
     CDS             53739..54377
                     /locus_tag="ACL3S0_000284"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGR1311267.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54494..54712
                     /gene="infA"
                     /locus_tag="ACL3S0_000285"
     CDS             54494..54712
                     /gene="infA"
                     /locus_tag="ACL3S0_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGR1311268.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54737..54853
                     /gene="rpmJ"
                     /locus_tag="ACL3S0_000286"
     CDS             54737..54853
                     /gene="rpmJ"
                     /locus_tag="ACL3S0_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGR1311269.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54871..55236
                     /gene="rpsM"
                     /locus_tag="ACL3S0_000287"
     CDS             54871..55236
                     /gene="rpsM"
                     /locus_tag="ACL3S0_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGR1311270.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55254..55637
                     /gene="rpsK"
                     /locus_tag="ACL3S0_000288"
     CDS             55254..55637
                     /gene="rpsK"
                     /locus_tag="ACL3S0_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGR1311271.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55680..56615
                     /locus_tag="ACL3S0_000289"
     CDS             55680..56615
                     /locus_tag="ACL3S0_000289"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGR1311272.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56627..57013
                     /gene="rplQ"
                     /locus_tag="ACL3S0_000290"
     CDS             56627..57013
                     /gene="rplQ"
                     /locus_tag="ACL3S0_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGR1311273.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57278..57544
                     /locus_tag="ACL3S0_000291"
     CDS             57278..57544
                     /locus_tag="ACL3S0_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGR1311274.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57554..58891
                     /locus_tag="ACL3S0_000292"
     CDS             57554..58891
                     /locus_tag="ACL3S0_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGR1311275.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59135..59827
                     /locus_tag="ACL3S0_000293"
     CDS             59135..59827
                     /locus_tag="ACL3S0_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR1311276.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(59930..61582)
                     /locus_tag="ACL3S0_000294"
                     /pseudo
     CDS             complement(59930..61582)
                     /locus_tag="ACL3S0_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(61572..62663)
                     /locus_tag="ACL3S0_000295"
                     /pseudo
     CDS             complement(61572..62663)
                     /locus_tag="ACL3S0_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62676..63797)
                     /locus_tag="ACL3S0_000296"
                     /pseudo
     CDS             complement(62676..63797)
                     /locus_tag="ACL3S0_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(64014..64238)
                     /locus_tag="ACL3S0_000297"
                     /pseudo
     CDS             complement(64014..64238)
                     /locus_tag="ACL3S0_000297"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(64286..65062)
                     /locus_tag="ACL3S0_000298"
     CDS             complement(64286..65062)
                     /locus_tag="ACL3S0_000298"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGR1311277.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            65184..65930
                     /locus_tag="ACL3S0_000299"
     CDS             65184..65930
                     /locus_tag="ACL3S0_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR1311278.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            65943..66923
                     /locus_tag="ACL3S0_000300"
     CDS             65943..66923
                     /locus_tag="ACL3S0_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGR1311279.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            67118..67438
                     /locus_tag="ACL3S0_000301"
     CDS             67118..67438
                     /locus_tag="ACL3S0_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR1311280.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67484..67792
                     /locus_tag="ACL3S0_000302"
     CDS             67484..67792
                     /locus_tag="ACL3S0_000302"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1311281.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67809..69107
                     /locus_tag="ACL3S0_000303"
     CDS             67809..69107
                     /locus_tag="ACL3S0_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR1311282.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSWYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            69258..71696
                     /locus_tag="ACL3S0_000304"
     CDS             69258..71696
                     /locus_tag="ACL3S0_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGR1311283.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            71715..72383
                     /locus_tag="ACL3S0_000305"
     CDS             71715..72383
                     /locus_tag="ACL3S0_000305"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGR1311284.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            72401..73489
                     /locus_tag="ACL3S0_000306"
     CDS             72401..73489
                     /locus_tag="ACL3S0_000306"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGR1311285.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            73944..76445
                     /gene="leuS"
                     /locus_tag="ACL3S0_000307"
     CDS             73944..76445
                     /gene="leuS"
                     /locus_tag="ACL3S0_000307"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGR1311286.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTS
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIVAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFVQLIAPFAPHL
                     AEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKVEIDGKEIVKVIAVPNKLVNIVVK"
     gene            76640..77335
                     /locus_tag="ACL3S0_000308"
     CDS             76640..77335
                     /locus_tag="ACL3S0_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR1311287.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQESVADMEELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPKLRGTRIGTEAQYLLARYVFEELNYRRYEWKCDSL
                     NLPSRRAAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKARLEAWLTPENF
                     DKTGQQYKSLREL"
     gene            77347..77763
                     /locus_tag="ACL3S0_000309"
     CDS             77347..77763
                     /locus_tag="ACL3S0_000309"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311288.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YVALDGDAVVGLIRLVGDGFSSVFVQDLIVLPNYQRQGIGSLLMKEALKDYKDAYQVQ
                     LVTEETEKNVRFYRSMGFEALSTYDCIGMTWVNREK"
     gene            complement(78600..78692)
                     /locus_tag="ACL3S0_000310"
     CDS             complement(78600..78692)
                     /locus_tag="ACL3S0_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGR1311289.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            78826..79824
                     /gene="ruvB"
                     /locus_tag="ACL3S0_000311"
     CDS             78826..79824
                     /gene="ruvB"
                     /locus_tag="ACL3S0_000311"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGR1311290.1"
                     /translation="MGRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            79805..80377
                     /locus_tag="ACL3S0_000312"
                     /pseudo
     CDS             79805..80377
                     /locus_tag="ACL3S0_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
     gene            80608..81366
                     /locus_tag="ACL3S0_000313"
     CDS             80608..81366
                     /locus_tag="ACL3S0_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGR1311291.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            81375..82178
                     /locus_tag="ACL3S0_000314"
     CDS             81375..82178
                     /locus_tag="ACL3S0_000314"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGR1311292.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            82200..83459
                     /gene="rseP"
                     /locus_tag="ACL3S0_000315"
     CDS             82200..83459
                     /gene="rseP"
                     /locus_tag="ACL3S0_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGR1311293.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            83472..85325
                     /locus_tag="ACL3S0_000316"
     CDS             83472..85325
                     /locus_tag="ACL3S0_000316"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGR1311294.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     SDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            85424..86803
                     /gene="bglA"
                     /locus_tag="ACL3S0_000317"
     CDS             85424..86803
                     /gene="bglA"
                     /locus_tag="ACL3S0_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR1311295.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGLRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYDNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            86995..88803
                     /gene="glmS"
                     /locus_tag="ACL3S0_000318"
     CDS             86995..88803
                     /gene="glmS"
                     /locus_tag="ACL3S0_000318"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGR1311296.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            88923..89972
                     /locus_tag="ACL3S0_000319"
     CDS             88923..89972
                     /locus_tag="ACL3S0_000319"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGR1311297.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKIGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
BASE COUNT        27044 a        16481 c        19921 g        26577 t
ORIGIN      
        1 aatagtccat gctgtggctg gattcttttc agcctactta tactcttcga aactctcttc
       61 aaaccacgtc agcttcacct tgccgtatat gtgttactga cttcgtcagt tctatccaca
      121 acctcaaaac ggtgttttga gcaacctgcg gctagtttcc tagtttgctc tttgattttc
      181 attgagtatt attaaaacaa tatgaggaga aagatgaaag aaaaaggatt ttaggagggg
      241 gcgcaggcag ccatgccaac ggctcttggc tatgtcagta tcggcctggc ctgtgggact
      301 atcggtgctc cctatgtgac acctgttgag atgggcttga tgagtctctt tgtttatgct
      361 gggagtgccc agtttgccat gttggcactg attgtggttc aagctcctgt ggcagctatt
      421 gctatgacgg tttttctaat caacttgcgt ctctttttgt tgagtttaca cgcatcgact
      481 tatttccgtc ataccagtct ttggtacaat atcggtatgt ctagtatctt gacagatgag
      541 acctatggcg ttttgatggg tgaattggcc catacagaca aggtaaatcc tatgtggatg
      601 cacgggaaca atctcaacag ctatgtggct tggtttgtgg ggacagtagt cggaacggct
      661 ctgggtggcc tgctaccaaa tccagaaatc tttggcttgg attttgccct ggttgggatg
      721 tttattggta tttttgcttc gcaatttcag attatgcaaa gacggattcc tgtccgcaat
      781 ctgctcatta tcctagcagt tgttgcggtg tccttctttt tgctcttgac agtggtgtct
      841 cagtcactag ctgttctgtt tgcgacgcta cttggttgta gcatgggggt ggttttagat
      901 ggtcagtaag tatcttttat tagcagttat tttctctggt cttgtgacct ggattccccg
      961 tatgattctc ttcatcttgg tcaagcataa gggcctgcct gcgattgttg agcgtttttt
     1021 gaagtttttg cctgtttcca ttatctttgc cttgattctt tcaagcgtag tgacaggtaa
     1081 ggttgggagc cttcctcaaa ttaaatggct agacttctta gccgtctttc caacagcttg
     1141 ggtagccttt cgctaccgca atctagtcgg aacagttctc tttggagtgg tcttgattgc
     1201 catcttgcgt ttggtctttt aaattaccca taaaaaaaac ttatcacaga gatagatatc
     1261 atataatggc gtaaatgctc tttttctgtt aagattataa ggtattctat tttggaggaa
     1321 atgacatgaa aaaaatcgtt aaatactcat ctcttgcagc ccttgctctt gttgctgcag
     1381 gtgtgcttgc ggcttgctca ggtggtgcta agaaagaagg acaagcagct agcaagaaag
     1441 aaatcatcgt tgcaaccaat ggatcaccaa ggccatttat ctatgaagaa aatggcgaat
     1501 tgactggtta cgagattgaa gtcgttcgcg ctatctttaa agattctgac aaatatgatg
     1561 tcaagtttga aaagacagaa tggtcaggtg tctttgctgg tcttgacgct gaccgttaca
     1621 atatggctgt caacaatctt agctacacta aagaacgtgc ggagaaatac ctctatgccg
     1681 caccaattgc ccaaaatcct aatgtccttg tcgtgaagaa agatgactct agtatcaagt
     1741 ctctcgatga tatcggtgga aaatcgacgg aagtcgttca agccactaca tcagctaagc
     1801 agttagaagc atacaacgct gaacacacgg acaacccaac tatccttaac tatactaagg
     1861 cagatttcca acaaatcatg gtacgtttga gcgatggaca atttgactat aagatttttg
     1921 ataaaatcgg tgttgaaaca gtgatcaaga accaaggttt ggacaacttg aaagttatcg
     1981 aacttccaag cgaccaacaa ccgtacgttt acccacttct tgctcagggt caagatgagt
     2041 tgaaatcgtt tgtagacaaa cgcatcaaag aactttataa agatggaact cttgaaaaat
     2101 tgtctaaaca attcttcgga gacacttatc taccggcaga agctgatatt aaataatttc
     2161 ttgaaatcat ccattctgag taagatgggt ggtttctcag tttttaggga tatagtttta
     2221 aactatatat ctgactatct aataacaatt tgtgaaatca aacaaattgt gagatactag
     2281 tacggtatta tttttaagga gaaagaatca tgaaaatcaa aaaatggctt ggtctagcag
     2341 cccttgctac agtcgcaggt ttggctcttg cagcttgcgg aaactcagaa aagaaagcag
     2401 acaatgcaac aactatcaaa atcgcaactg ttaaccgtag cggttctgaa gaaaaacgtt
     2461 gggacaaaat ccaagaattg gttaaaaaag acggaattac cttggaattt acagagttca
     2521 cagactactc acaaccaaac aaagcaactg ctgatggcga agtagatttg aacgctttcc
     2581 aacactataa cttcttgaac aactggaaca aagaaaacgg aaaagacctt gtagcgattg
     2641 cagatactta catctctcca atccgccttt actcaggttt gaatggaagt gccaacaagt
     2701 acactaaagt agaagacatc ccagcaaacg gagaaatcgc tgtaccgaat gacgctacaa
     2761 acgaaagccg tgcgctttac ttgcttcaat cagctggctt gattaaattg gatgtttctg
     2821 gaactgctct tgcaacagtt gccaacatca aagaaaatcc aaagaacttg aaaatcactg
     2881 aattggacgc tagccaaaca gctcgttcat tgtcatcagt tgacgctgcc gttgtaaaca
     2941 ataccttcgt tacagaagca aaattggact acaagaaagc acttttcaaa gaacaagctg
     3001 atgaaaactc aaaacaatgg tacaacatca ttgttgcgaa aaaagattgg gaaacatcac
     3061 ctaaggctga tgctatcaag aaagtaatcg cagcttacca cacagatgac gtgaaaaaag
     3121 ttatcgaaga atcatcagac ggtttggatc aaccagtttg gtaataagaa acagggaggt
     3181 gggagagaga attccacctc ttgcttttgt atagagcacg gagtgtaaag aagactattc
     3241 gttcatagaa aggtagagag aatatggttt ttcctagcga acaagaacag attgaaaaat
     3301 ttgaaaagga tcatgtagcc cagcattatt ttgaggtttt gcgtaccttg atttctaaga
     3361 aatcagtctt tgcccagcag gttggactca aggaagtcgc aaattatctg ggtgagattt
     3421 tcaagcgtgt tggagctgaa gtggagattg atgagagcta tacagcgccc tttgtcatgg
     3481 cacatttcaa gagttcgcgt ccagatgcca agaccttgat tttctataac cactatgaca
     3541 ctgtgccagc ggatggggat caggtctgga cagaggatcc ttttacgctt tcggtccgca
     3601 atggcttcat gtatgggcgt ggagttgatg acgacaaggg tcatatcaca gctcgcttga
     3661 gtgctttgag aaaatatatg cagcaccatg atgatttacc tgtcaatatc agctttatca
     3721 tggagggagc ggaggaatcg gcttcaacag acctagataa gtatttggaa aagcatgcag
     3781 acaaactccg tggggcggat ttgttggtct gggaacaagg gaccaaaaat gccttggaac
     3841 agctggaaat ttctggtggc aataagggga ttgtgacctt tgatgccaag gtaaaaagcg
     3901 ctgatgtgga tatccactcg agttatggtg gtgttgtgga atcagctcct tggtatctcc
     3961 tccaagcctt acagtctctt cgtgctgcgg atggccgtat cttggttgaa ggcttgtacg
     4021 aagaagtaca agagcccaat gaacgagaaa tggccttgct agaaacttat ggtcaacgaa
     4081 acccagagga agttagtcgg atttatggat tggagttgcc tctcttacag gaggagcgga
     4141 tggcctttct aaaacgtttc tttttcgagc cagcgcttaa tatcgaagga atccagtctg
     4201 gttatcaagg tcagggtgtg aagactattt tacctgcaga agccagtgcc aagctagagg
     4261 ttcgtctggt tccgggccta gaaccgcatg atgttctgga aaaaattcgg aaacagctag
     4321 acaaaaatgg ctttgataag gtagaattat actatacctt gggagagatg agctatcgaa
     4381 gcgatatgag cgcaccagcc attctcaatg tgatcgagtt ggccaagaaa ttctatccac
     4441 agggcgtttc agtcttgccg acgacagcgg ggacaggacc tatgcatacg gtctttgatg
     4501 ccctagaggt accaatggtt gcattcggtc taggaaatgc caatagccga gaccacggtg
     4561 gagatgaaaa tgtgcgaatc gctgattatt acacccatat cgaattagta gaggagctga
     4621 ttagaagcta tgagtagaga tattatcaag ttagatcaga tcgatgtgac ttttcaccaa
     4681 aagaagagaa ccatcacagc ggttaaggat gtgaccattc acatccaaga aggggatatc
     4741 tacggaatcg ttggatattc tggagcaggg aaatcaaccc ttgtacgggt gattaatctc
     4801 ttgcaaaaac catctgcagg gaaaattacc attgacgacg atgtgatttt tgatggtaag
     4861 gtcaccttga cggcagagca gttgcgtcgt aaacgtcaag atatcgggat gattttccag
     4921 cattttaacc tgatgagtca aaagacagca gaggagaatg tagcctttgc ccttaaacac
     4981 tctggactca gcaaggaaga aaagaaggct aaagtagcta agttgttgga cttggttggt
     5041 ttggcagatc gtgctgaaaa ctacccttca caattatctg gagggcaaaa acagcgtgtg
     5101 gcaattgcgc gtgccttggc caatgatcca aaaatcttga tttcagacga gtcaacttct
     5161 gcccttgacc ctaagacaac caagcagatt ttggccttgt tgcaagattt gaaccaaaaa
     5221 ttaggcttga ctgttgtctt gattacgcat gaaatgcaga ttgtcaaaga cattgccaac
     5281 cgtgttgcag ttatgcagga tgggcatttg attgaagagg gtagtgtgct tgaaatcttc
     5341 tcaaacccta aacaaccttt gactcaagac tttatctcaa cagctacagg tattgacgaa
     5401 gccatggtca aaatcgagaa gcaagaaatc gtggaacact tgtctgaaaa cagtctcttg
     5461 gtgcaactca agtacgctgg agcttcaaca gacgagccac ttttgaatga attgtacaag
     5521 cattaccaag taatggctaa tattctctat gggaatatcg aaattctcga tggtactcct
     5581 gttggagaat tggtggtggt tttgtcaggt gaaaaagcag cgttggcagg tgcccaagaa
     5641 gccattcgtc aagcaggtgt acaactaaaa gtattgaagg gagtacagta agatggaatc
     5701 attgattcaa acctatttac caaatgtcta taaaatgggt tgggctggtc aggcaggctg
     5761 gggaacggct atctacttaa ctctttatat gacagttctt tccttcatta tcggaggctt
     5821 cttggggcta gtggcaggtc tctttctcgt cttgacagcg ccaggtggtg tcttggagaa
     5881 taaagtcgta ttctggattt tagacaaaat tacctcaatt tttcgtgcgg ttccctttat
     5941 catcctcttg gcaatcttgt caccactttc tcacttgatt gttaaaacaa gtatcgggcc
     6001 aaatgcagcc cttgtcccac tttcttttgc agtctttgcc ttctttgccc gtcaggtgca
     6061 ggttgtcttg gctgaattgg atggcggtgt cattgaggcg gctcaagcga gcggagcgac
     6121 tttctgggac atcgtgggtg tttacctatc agaaggtctt ccagatttga tccgtgtgac
     6181 gactgtgacc ttgatttccc ttgttgggga aacagctatg gccggtgcgg ttggagctgg
     6241 tggtatcggt aacgtagcca tcgcttatgg atttaaccgc tacaatcacg atgtgaccat
     6301 cttggcaacc atcattatca ttttgattat ctttgcaatc caattcttgg gagatttctt
     6361 gactaagaaa ttgagccata aataaaaaag agccgcgtgg ctctttttaa ctgatcagat
     6421 tttctgtgca aattttttac tcaaggcttg tccaatcaag gcacccacta gggctccgat
     6481 gacaatactt gcgataaata gaaggacagt tccagggttt ggagcgacca tgatgcggtc
     6541 gatatattct tgggattttc ctcttgccag aagagtagcc atataggctt tgggcgcaat
     6601 ccacataagc aagattggtc ctgttgtact aaaggcgaaa ataatgaaag aaaggaagtt
     6661 ctttgttttg tccttgtatt ttcctaaatg agctacttca tctgctagga ggccacagat
     6721 aattccagga aggaaggaac cagcaccgtg tttagttccc aagaaaaaga gggcaatgac
     6781 aaggccgata gtggtaatgg ctccaaagcg cggaactttt gcgactagga tcatatagac
     6841 gctaccgccg acaagggcag taaaggcagg cgcataaaac atgtttccag tttggtcaaa
     6901 gagattgccc aaaaggacac caatccccat gcagaggaag taaagaactg caaaaagcag
     6961 tgtagttaag atagatttct tcatgaattg tctcctgata attttttcac aattctcatt
     7021 gtaccacggt ttggtgggat tgtaaatgga tactagaagt ttttgaaaac gcttgaaata
     7081 tgatataatg gtttcatagt tatttttagg ggaatatcat gggtagattt ttagactttg
     7141 tctttaatcg tttcttttta gggatgattg cgacagcctt cttttggcta ttaactttag
     7201 taggagggat tatccttggt ctagcgccag ctagtgccac cttgatgagc ttatatgcag
     7261 aacatggtta tagctttcgg gaatacagtt tgaaggaggc ttggtctctt tacaagcaaa
     7321 attttgtctc aagcaacctg attttctata gctttttagg tgtgggtcta gttttgacct
     7381 atggtttgta tctcttggtg caattgcctc atcagaccat tgttcatttg attgcgaccc
     7441 ttttgaatgt cctagtagtt gccctgatct ttttggctta tacagtatct ttaaaattac
     7501 aagtttattt tgccttgtcc tatcgaaata gtctcaaatt atccttgatt ggcatcttta
     7561 tgagtctagc agctgtggcc aagattctcc ttgggactgt gctacttgta gcaattggtt
     7621 actatatgcc tgccctgcta ttttttgtag gaattgggat gtggcatttc tttatcagtg
     7681 atatgttgga acctgtctat gaaatcatcc atgaaaaatt ggcgacaaaa tagaatgaag
     7741 cacttttggc tacatacgct tctaagaacc tatagttcag tgatgatcat tatcattgcg
     7801 agttttgcaa tcttactctc ttacgctgac tgggattcac gtgaaaagga agcccagaga
     7861 gtagcccagc gtgtaactgc tagaacagtg agtgaaattg aatattacca tagagagtca
     7921 acccagatag ctcaggcttt agttgaaaac caagctcgta ttgagggaat ctataaatac
     7981 tttagcctta gcatgccaga ctatttttac tggcaattag agcggaaagc ttcgccttat
     8041 atatcagtct ctctgtatga aaatgttgat gacctctatg ttcgaaatga ttttgtaact
     8101 ggggtggcca ttgcttttca agattacaag gaagtctatg tttctactaa agacaaacgt
     8161 agtggagaaa aaatcagggc tgaggatttc aaaccagcag gaaatagttt tgccattccg
     8221 gtgtcagatc cagtgtcaga tcaagattta ggagtgattt acatctcctt ggatcctgct
     8281 gttttatacc atgccattga taatactaga ggtcatactc cgatggcagt aacagtgacc
     8341 tcaccttttg atacggagat ttttcatatt ggtgagacag ttgataggga gagtgaaaat
     8401 tggctagttg gcttaacttc tcatggatat caggttcagg tggcagttcc taaaaacttt
     8461 gttttacaag gaacagtgac tagctctgct ttgattgtgg gtttgagcct tctctttatt
     8521 gtcattcttt atctgacttt gaggcagact tttgctaatt accaaaagca ggtagtggat
     8581 ttagtagaat ccattcaagt cattgctcaa ggcgaagagg ggcgtcggat tgacatttcc
     8641 gagaaagatc aggaattact cctaatcgcg gagacgacca atgatatgtt ggatcgattg
     8701 gaaaagaata tccatgatat ttaccagtta gagcttagtc aaaaagatgc caatatgcga
     8761 gccttgcagg cgcaaatcaa tcctcatttt atgtataata cgctggagtt cttgcgcatg
     8821 tatgcagtta tgcagagtca agatgagttg gcagatatca tttatgaatt cagtagtctc
     8881 ttgcgtaaca atatttccga cgaaagagag accctcctca aacaggaatt agaattttgc
     8941 cgtaaataca gctatctctg catggttcgc tatcccaagt ccattgccta tggtttcaag
     9001 atagatccag agttagagaa tatgaagatt cccaagttta ccttgcaacc gctggtagaa
     9061 aactatttcg cgcatggtgt tgaccacagg cggacagata atgtgattag catcaaggct
     9121 cttaaacagg atggttttgt ggaaattttg gtggtcgata atggtagagg aatgtcggct
     9181 gaaaagttgg caaatatccg agaaaaatta agtcagagat attttgaaca ccaagccagc
     9241 tacagtgatc aaaggcagtc tatcgggatt gtcaatgtac acgagcgttt tgtgctctat
     9301 tttggagacc gctatgccat tactatagag tctgcagagc aagccggtgt tcagtatcgt
     9361 attacaattc aagatgagta gaaagggaga aaatgtataa agtattatta gtagatgatg
     9421 agtacatggt gacagaaggt ctgaagcgtt tgattccctt tgataagtgg gatatggagg
     9481 ttgtcgcaac agccagtcat gccgatgaag ctctagaata tgttcaggaa aatcctgtcg
     9541 atgtcatcat ttccgatgtc aatatgccag acaaaacagg gcttgatatg attcgggaga
     9601 tgaaagagat cttaccagat gctgcctata tcctgctctc aggttatcag gagtttgatt
     9661 atgtaaaaag agcaatgaac cttagtgtgg tggactattt ggtcaagcct gttgataagg
     9721 tagagctggg aaatctgctg gagaagattg caggtcagct cggcgagaga gggaagaaaa
     9781 gtcagactct tagtcaagaa ttagacgagg ctggatttgt tagttattta ggggataagg
     9841 agaattggtg gataggtcta tccaaggaaa aacaaggttc cttcaccatt ccctactatg
     9901 tcttgggcca agactggcag attttcattt ctggccaacc tctagatggt ttagtcgtta
     9961 caccttttga agctccttat caagaacact ttgaacgctg gaagctgaat gctgagaaaa
    10021 ccctctttta cggttctgta aatttgcagc agtctgagag tctctttgcc tattacgaac
    10081 cgatttatag ggttatcatt cagggaaatc tcaatcaaat cgtagaagag ttaaatctct
    10141 tggagaaggt agttcttgaa aatacgccgc gtgttccgat tactaaacag ctttttattc
    10201 agtttgtcat ggatgttttc catttatttg aacatctcaa agctgatgac ctgacagaca
    10261 tcgtcaaaac cattcatgct attcaatcct tcgatgaatt ggtttcttat atcaaggaaa
    10321 ctctgatcag ctttttcggt caataccgta tgaatgaaaa tgtggtcagt gtgctggaag
    10381 tcattggtcg tgattaccaa aaagagcttt ccctcaagga tatcagtaag gctctcttta
    10441 tcaatcctgt ctatctaggg cagttgatta agcgtgaaac cgattcgacc tttgcagagt
    10501 tactaaacaa acaacgtatt aaggctgccc aacaactttt gctttcaact agtgacagca
    10561 tcgaagatat ttgttatgct gttggttaca gtaaccttgg atatttctat aaagttttcc
    10621 gaaaattgtg cggaaaatcg ccaaaagcct accgaaaaca ggtagaaact atactataaa
    10681 atttgtattc ctttacaaaa ggtgctataa tattatcagg aggttctatc atgaaaaaga
    10741 aaccaattta tctatgggtc ttgctaatct tgtctgccct tatttcagtt ccgtctctgt
    10801 ttggaattgt gagtcccttg cctagtaagg aagcccttcg tgctgctcag aaacaagttg
    10861 caggggtcaa tgctcagcaa ttagaagacc agcttaatta tacctataga gtagcagaag
    10921 catctcattc tatttttaat gttgctttga ttgtgctatc tactatttta gtggtcgtag
    10981 cgattgtctt ccttgttcgt aaaaatttgc aatatgcaaa ctatacttac gttggctatg
    11041 ttttgttagc tattattggt tcgatttatg gctatgttgg tttacaagac gctgtgcagt
    11101 tggttcaaga tgagagcatg cgtttgacag tgagtattgg ttcaaaagct gttagcattt
    11161 tctatatcgt catcaatgtt ctcttcctag cccttgtctt ctataagatg tggcgacaac
    11221 agaaagcctt ggcagaagaa gaggaaacag aagagcttgc ctaagtattg acaaaaaaga
    11281 actatcaaga tacaatcttg gtagttgttt tttgattata gataaaatca tggaggtaca
    11341 tatgaagaca atttctttag tttatattag tttgagtggc aacactgaaa gttttgtgac
    11401 gcgcttgaaa gactatctct tgtcccagta caaagggatt gaggttcaaa agattcatat
    11461 caaggattta gtcaaggaag gcaaaaattt ctatgaaatg gaccatccct atgtcgcttt
    11521 tttgccgacc tatctcgaag gtgggaatgg cgtggataac ggagatgttg agattttgac
    11581 gacaccggtg ggagatttta ttgcctatgg taacaatgct agtaagtgtt ttggtgtggt
    11641 tgggtcagga aatcgtaact ttaataacca atactgccta acagccaagc aatacagtca
    11701 acgctttggc tttcctgtat tggctgactt tgaaatgcga ggcatgctgg aagatatcaa
    11761 acatgtcgca gctattatcg cagatttgta tgagttggaa aaggagaatt aatactcaat
    11821 gaaaatcaaa gagcaaacta ggaagctagt cgcaggttgc tcaaagcaca gctttgaggt
    11881 tgcagataga gctgacgtgg tttgaagaga ttctcgaata gtataaagtt cttataagag
    11941 gtggttgaag ttgttcaact gttttttgag tataaacagt ctttaagaac gtaaaaaagc
    12001 ataagttcag gtcttcaaaa ccttgttctt atgcttttta tcatagaaat atttgctgaa
    12061 ttttctcttg aaatgaaacc ttatcttcat ctcgcgcttg tcccttaccc tgcttttccg
    12121 attgcgagtg cgtagataaa gaagatggcg aagccaaaga ggaaaatcaa tcccgcaatg
    12181 gcaaggtgtt tgagccaaga aggaagattt ttgttttcac gcgttaccaa ggcgtaattc
    12241 aaaagagcaa agaaaggtgt tgtcaggaaa gagccaatca tggcaaagcg gagcatggtt
    12301 gaaacctgac cagcgaagaa cttgataatg acgataccga tgatagcagt gatggtcatc
    12361 cagatgttca aagatttacg attgtcctct ttttgactga ttagcagtcg gagagattcc
    12421 tgattaacgc gagaatagcc atcgataaca gttataactg ttccaaagat acagaggaag
    12481 gcaataaagg taatcaagta acgggaccat tcgccaagaa cagaggcata catgcccacg
    12541 aattgagaga tgtatttggc tgaagcagct tcaaccgcct gccctgtagg atactgaatc
    12601 agtgctccca gtgccacaaa gaagacggct aggatagctg ttccaatata accagtgtta
    12661 aagtcaaaca cagcgtcttc tgtgttaaag ttgacggtct ttctcttttc agctgaccaa
    12721 agtgaattga tggctgaaat ttcaatagga gccggcatcc atcctaggag ggagacgatg
    12781 aagggcagag ctgccatttg ccaaggtgtc ttctcgacaa aatcagaact gtattctgga
    12841 tgcttgaccg ccgcaatgat aactgcaaga acagtcgcaa tggttaaggc agacataatc
    12901 catttgacca tgccgtctaa aagtttgtag cctccaaaga gtagcatagc ccaaatgatt
    12961 gcaacgagaa tgagggacca ctgagtaatg ctaagtccaa tcattgggaa ggcactggcg
    13021 atgatagctg agcacagaat ggcaacacca gccgtgttga ccatagccga aaagacattg
    13081 aggataaaga aaatccagag atagagtttt cctttttcgg cataaccttc aaccaaagtc
    13141 tttccagtat cagctgtgta ttcagcacca aaacggaaaa atggatattt aaagacattg
    13201 gctaagatga ccaagagaag tagagaccaa ccgtaagaac cgccagcttg agttgaggat
    13261 acaatgtggg aacctccaac agcggcagtt gccattagga ttccaggtcc cattgctttt
    13321 agcttgcttg cccaggttga ttgatttaag gaaatagctt gcgacatgat aaatactcct
    13381 ttttgaattt tcagaataat ctgtatatgt aatctatatt ctacaaaaaa ttttggaaaa
    13441 atgcaagagt attttgaaaa aagatagaaa atttacaaag aaaatctgaa ataactgtta
    13501 tgatatagca gattgaaact agaatagtac acttttgctt ctaaaacatt gttagaaatc
    13561 gatttgactg tcctgattga tttaccctgt tcttatttca tttcactata gtaaggtgca
    13621 gcaggataaa gcaaaaccga gaagtttctt tctcggtttt gcttattatg aggttcctat
    13681 tttctatgct ccaagagttg attgatgtga tctacttttt tagcctctct tttatagaga
    13741 atagcccaga tgatgagata gacaatcgca aactcgataa tgagctggag gtagaaaatc
    13801 cagtggaagg ggaaccaacc agcaagagtt gctagtggga caaagccagc cagcataagg
    13861 aagaaatgag tcagagtggc acgaagcatg ctccagtcac ggctgaataa gcggttgcca
    13921 aagttgaaga gcataccgat ggctgcccag ataagtgtgc agtagagcaa gaccagggca
    13981 ccgtgaacct gatgctgatc catcacttgg ccgatgagag agtagggatt tagtggtgcg
    14041 taggtatttg gtgcataaat gagtgaaaag aggatggaga ggatgaggcc gataagaaca
    14101 ccggcagctg catcgtgaaa tacttgtttt ttcatagttc taatttctcc ttgatggttt
    14161 ttagataacg gcgtgaagag taggtgaagc tttcgttttt caagaaaatt tctaccagac
    14221 cgtttggcgt gagcttgagg tgagagatgg aatcgatatt gatgatttct gattgggaaa
    14281 tttggataaa attggttggc aagagtttaa gaacctgata gagtcgcaaa tcaatgctgt
    14341 aggtctgact cgcggtttct gctagaacct tccgattctc gatatagaag cgctgaatct
    14401 tgccaatctc aactagatag acctgatcat cgatttttcc tttgattttt tctctttggt
    14461 ccagattttc tgcgaactcg atgactttct ggactttttc ggtttcttga ggtgcttgga
    14521 caatcagctt ttcctcctcg taagtctcac taatctgtag ttctactttc ataaatttct
    14581 ctccttgttt ttcatacaaa attaatctca cttcttgtac acctttatta atactcttca
    14641 aaaatctctt caaaccacgt cagcgtcgtc ttgccgtagg atagttgttg actttgtcag
    14701 ttttatctac aacctcaaaa cagtgttttg agctgtctgc gtctagcttt ctagtttgct
    14761 ctttgatttt tattgagtat accactattt tactccctct ggcaagggac tttgtctatg
    14821 tggagggatt gggctcctat gtggtggagt ttttctgttc tttctgaaat atggtataat
    14881 agcactaatt aatttctagg aaaatagata cagaaagggg ctgaaagatg tctcatatta
    14941 ttgaattgcc agagatgctg gcaaaccaaa tcgcagctgg ggaggtcatt gaacgtcctg
    15001 ccagtgtggt taaagagttg gtagaaaatg ccattgacgc gggctctagt cagattatca
    15061 ttgagattga ggaagctggt ctcaagaagg ttcaaatcac ggataacggt catggaattg
    15121 cccacgatga ggtggagttg gccctgcgtc gccatgcgac cagtaagata aaaaatcaag
    15181 cagatctctt tcggattcgg acgcttggtt ttcgtggtga agccttgcct tctattgcgt
    15241 ctgttagtgt cttgactctg ttaacggcgg tggatggtgc tagtcatgga accaagttag
    15301 tcgcgcgtgg gggtgaagtt gaggaagtca tcccagcgac tagtcctgtg ggaaccaagg
    15361 tttgtgtgga ggatctcttt ttcaacacgc ctgcccgtct caagtatatg aagagccagc
    15421 aagcggagtt gtctcatatc attgatattg tcaaccgtct gggcttggcc catcctgaga
    15481 tttcttttag cttgattagt gatggcaagg aaatgacgcg gacagcaggg actggtcaat
    15541 tgcgccaagc aatcgcaggg atttacggtt tggtcagtgc caagaagatg attgaaattg
    15601 agaactctga cctagatttc gaaatttcag gttttgtgtc tttacctgag ttgactcggg
    15661 ctaaccgcaa ttatatcagc ctcttcatca atggccgtta tatcaagaac ttcctgctca
    15721 atcgtgctat tttggatggt ttcggaagca agcttatggt tggacgtttt ccactggctg
    15781 tcattcacat ccatatcgac ccttatctag cggatgtcaa tgtgcatcca actaagcaag
    15841 aggtgcggat ttccaaggaa aaagaactga tgaccctggt ttcagaagct attgcaaata
    15901 gtctcaagga acaaaccttg attccagatg ccttggaaaa tcttgccaaa tcgaccgtgc
    15961 gcaatcgtga gaaggtggag caaactattc tcccactcaa agaaaatacg ctctactatg
    16021 agaaaactga gccgtcaaga cctagtcaaa ctgaagtagc tgattatcag gtagaattga
    16081 ctgatgaagg gcaggatttg accctgtttg ccaaggaaac cttggaccga ttgaccaagc
    16141 cagcaaaact gcattttgca gagagaaagc ctgctaacta cgaccagcta gaccatccag
    16201 agttagatct tgctagcatc gataaggctt atgacaaact ggagcgagaa gaagcatcca
    16261 gcttcccaga gttggagttt ttcggacaaa tgcacgggac ttatctcttt gcccaagggc
    16321 gagatggact ttacatcata gatcagcacg ctgctcagga acgggtcaag tacgaggagt
    16381 accgtgaaag cattggcaat gttgaccaga gccagcagca actcctagtg ccctatatct
    16441 ttgaatttcc tgcggatgat gccctgcgtc tcaaggaaag aatgcctctc ttagaggaag
    16501 tgggcgtctt tctagcagag tacggagaaa atcaatttat tctacgtgaa catcctattt
    16561 ggatggcaga agaagagatt gaatcaggca tctatgagat gtgcgacatg ctccttttga
    16621 ccaaggaagt ttctatcaag aaataccgag cagagctggc tatcatgatg tcttgcaagc
    16681 gatctatcaa ggccaatcat cgtattgatg atcattcagc tagacaactc ctctatcagc
    16741 tttctcaatg tgacaatccc tataactgtc ctcacggacg tcctgttttg gtgcatttta
    16801 ccaagtcgga tatggaaaag atgttccgac gtattcagga aaatcacacc agtctccgtg
    16861 agttggggaa atattaaaag tataaaaaag tctgggaaaa attttcaaaa tcagaaaaac
    16921 gcataaaatc aggtgttcaa aaaccttgat tttatgcgtt ttatcataga aatatttact
    16981 tcatgttttc ctaattcttt tcgaaactct ttttaaacca cgtcagtttt atcagtaatc
    17041 tcaaaacagt gttttgagct aattttgcca gttttgtctg taacatcgaa gttgtgtttg
    17101 accactctgc gactggtttc ctagtttgct ctatgatttt cacagagtat taaattgcga
    17161 ttttgccaag tttctttatt cgtctaaaag tagagtctgt tctatgcgtc taatgtacga
    17221 attaggttga ccatttcaat agctccttgt gcacactcag aacccttatt tcctgcttta
    17281 gtgccagctc gttctatggc ttgttcaatt gtatctgtcg ttagcacacc aaacataaca
    17341 ggaatttcgc tatttaaact gatttgggcg attcccttag atacctcgct acatacataa
    17401 tcataatgac ttgtattccc tctaatgaca gctcccaagc agataattgc atcatatttt
    17461 ttactttttg ccatttttga tgcaatcagt ggtatttcaa aagctcctgg aacccaggct
    17521 acctctatat ctttctcgtt tacattctct cttttgagat tatctagtgc tccagataat
    17581 aattttgaag ttataaattc attaaatctc gctacaacaa tacctatttt aatattgttt
    17641 gctactaaat taccttcata agtgttcatt tatttttcct ccatatttaa aatgtgaccc
    17701 attcgatttt tctttgtttc taaataaaaa ctatcgtaag gattggcttc tatttcgatt
    17761 gatattctac tggaaatggt aattccatat ttttctaact gttcaacctt gtcaggatta
    17821 tttgtcagta aatgaagtga ctgaagtccc agatctttaa gcatttgtgc tccaatatga
    17881 tattctctta aatcaccttc aaagcctaat gcaagattgg catcaagcgt atccatgcct
    17941 tgatcttgta aatgataggc ttttaattta ttgataagtc caattcctcg tccctcctgt
    18001 cgcaagtaaa gtaagacacc cgaaccattc tcaacaatca ttttcatagc tttatcgaat
    18061 tgctgtccac aatcgcaacg taaggagcct aaaacatccc ctgttaaaca ttcggagtgg
    18121 acccgacata atacattggc ttcatcctct atgtttccca taataagagc aagatgatgt
    18181 tccccattta gtttatctat atagctaatt gctttgaaat taccgtatct agtaggcata
    18241 ttgacagttg aaactcgttc taccagctga tcatatactt ttctatattc ttgtaattct
    18301 ttgatggtaa ttagtggaat gttgtgtttc ttcgagaact gaattaaatc atctgttctc
    18361 atcattttgc catcatgatt cattatttca caacataggc cacactcttt tagtccagct
    18421 aattttaata aatcaacagt tgcttctgtg tgtccacttc tttctagaac accacctttt
    18481 tttgcaatta aaggaaacat gtgtcctggc ctgcgaaaat cagagggtgt tatatcttca
    18541 gctacacaca tacgtgcggt cagtcctctt tcctcggcag aaatacctgt ggtcgtttct
    18601 ttataatcaa ttgaaactgt aaaagcagtc ttatgattat ctgtattgtt ttcaaccata
    18661 ggtgaaagca ttaattgatt agctaaactt tcgctcatag gcatacaaat taatcctttg
    18721 gcataagtag ccataaaatt aacattttct gttgtagctg cttgtgcaga acaaattaag
    18781 tctccttcat tttctctatc cttgtcgtct ataacaagaa caagtcgtcc cttctgcaat
    18841 gcttctaatg cttcttgtat ttttcgatat tccattgact gattatcctt tctgctaaaa
    18901 tccattttga tataatagtt ccttagatat ttctgatttt ggagagttat ccatcagttt
    18961 ttgcacatat ttacctaaga tatcattttc aagatttact gtactcccga cttgtttact
    19021 cttaagaatg gtttgttcca aggtatgagg gataacagat actgaaaagt ttactttgga
    19081 gactttagcg acagtcagac taatgccgtc aattgtaata gatccttttt caactattaa
    19141 atctaaaatt tctttttgtg tgttgatttg ataccataca gcattatcat ctttttttat
    19201 tgacgagatt tttcctgtac catcaatgtg tcctgtaacg acgtgacccc caagtcgacc
    19261 gttgacagat aaggctcttt ctagattcac ctcacttcca tgttttaata gagtaagagc
    19321 tgttcgactc catgtttcat tcattacatc aactgtaaag gattgatgat tgaaatgagt
    19381 aactgtaaga cagataccat ttactgctat actatcgcct aaatggatat ccgttaatat
    19441 ttttgaggct ttaattgata gtttacaatt acgagagtct ttctgtattc tttcaacttt
    19501 tccgatttct tcaattattc ctgtgaacat ggataaatca cttcactttc tatgagatag
    19561 tcatttccta tttgagaaaa tgcataaggt ttcaatctaa tagcgtcatt tggcaaagaa
    19621 ataccttcac ctccgacagg aaacttggca ctacctccaa aaatttttgg tgcaatatat
    19681 attttcagct catcaacaat ttgttgttcc aaagcactcc aattcattag actgccccct
    19741 tctagaacta ggctatcaat ctgcatgttt cctagatgtt gcattaaact cgataagtct
    19801 atatgattgc cttttttctt tatggaaagt atttcacagc catgattttg atatagcttc
    19861 attttatttt tgtcttcaga ggaagtggca atgtaagttt taatatcatt tgctgttttt
    19921 acgattttag aggtaagagg agttcgtaaa tgtgtatcgc atatgatacg gataggattt
    19981 ttcccttcct ccaatctaca tgtcagcaaa ggatcgtctt gaataacagt attgactccc
    20041 accataattg cactaacatg gtgtcgtaac tgctgcacat gctttcttgc ttcttcttca
    20101 gtaatccatt tggattgatt tgttttagtg gctatttttc catccattga cattgcatat
    20161 ttcataaaaa catagggtac atgctgggta atatactttc taaaactttt tattaagtta
    20221 agacactcat tttctaaaat tccaacagta acttgaagat tattttcctc aagtatcttt
    20281 actccttttc cagatacaat aggattacag tctaggcttc caatgactac tcttgtaata
    20341 ccactatcga ttatagcatc tatacaggga ggtgttttcc cgaagtgaca acagggttca
    20401 agtgttacat aaagcgtcgc tccgacaggg gattctctac agtttttaag agcatttctc
    20461 tcagcatgtg ggccaccaaa aaactcatga taaccttgtc cgataatgtg attatctttt
    20521 acaataactg cgccgaccat aggattggga ttgacgtaac cagccccttt ttgtgccagt
    20581 tttattgcta atttcatata ttttgaatcg ctcatctcac tacctccaaa aaaatatgcc
    20641 ttgaataggg gactactcaa ggcatacaaa agaaaactta tgcgattaac aaaaatgctc
    20701 tgaaatgaca agtaatcatt tcagagcacg caaaaagcac aaatatactt ttatcttctt
    20761 tcatccagac tatactgtcg gctttggaat ttcaccaaat catgcctttc ggctcgtggg
    20821 ctataccacc ggtagggaat tgcaccctgc cctgaagata gttattcaat tacagatgat
    20881 tatagtactt aattttgaat atgtcaacag ataaataccg attgtttttg atatactgta
    20941 tttgtgataa tcgattctcg ctcctcggat aaagaaaata tgatatacta gataaacgaa
    21001 ataagagaga aggaatacta tgtacgcata tttaaaagga atcattacca aaattactgc
    21061 caaatacatt gttcttgaaa ccaatggtat tggttatatc ctgcatgtgg ccaatcctta
    21121 tgcctattca ggtcaggtta atcaggaggc tcagatttat gtgcatcagg ttgtgcgtga
    21181 ggacgcccat ttgctttatg gatttcgctc agaggatgag aaaaagctct ttcttagtct
    21241 gatttcggtc tctgggattg gtcctgtatc agctcttgct attatcgctg ctgatgacaa
    21301 tgctggcttg gttcaagcca ttgaaaccaa gaacatcacc tacttgacca agttccctaa
    21361 aattggcaag aaaacagccc agcagatggt gctggacttg gaaggcaagg tagtagttgc
    21421 aggagatgac cttcctgcca aggtcgcagt gcaagcaagt gctgaaaacc aagaattgga
    21481 agaagctatg gaagccatgt tggctctggg ctacaaggca acagagctca agaaaatcaa
    21541 gaaattcttt gaaggaacga cagatacagc tgagaactat atcaagtcgg cccttaaaat
    21601 gttggtcaaa taggagcaga gaatgacaaa acgttgttcg tgggtcaaga tgaccaaccc
    21661 gctctacatc gcctatcatg atgaggagtg gggccagccc ctccatgatg accaagtatt
    21721 gtttgagttg ttgtgtatgg aaacctatca ggcaggcctg tcttgggaaa cggtactcaa
    21781 caaacgccaa gctttccgag aagtctttca tagctatcaa attcactcag tcgcagagat
    21841 gactgacact gaattggaag ccatgctgga gaatccagct atcattcgaa atagagccaa
    21901 gctttttgct acacgcgcta acgcccaagt ctttctacag ttacaggcag agtacggctc
    21961 ttttgatgcc tatctttggt cttttgttga ggggaaaact gtcgttaacg atgttcctga
    22021 ttatcgccaa gcgccagcta aaacaccctt atctgagaaa ttagccaaag atctcaaaaa
    22081 acgaggcttc aagttcacag gcccagtcgc cgtattgtct tttctacagg ctgcagggct
    22141 agttgatgac cacgagaatg attgtgagtg gaaaggtctt aaatgatgtc taacaaaaat
    22201 aagggaattc tgatttttgc gattctctat acagtcctct ttgtgtttga tggcgttaaa
    22261 ttgctggctt ctttaatgcc atctgtcatt gcaaattatc ttgtttatgt agttttagct
    22321 ttatatggct ccttcttgtt caaggataga ttgatccaac aatggaagga gattagaaag
    22381 actaaaagaa aattcttctt tggcgtctta acaggatggc tctttctcat tctgatgact
    22441 gttgtctttg aatttgtatc agagatgttg aagcagtttg tgagactaga tggacaaggt
    22501 ctaaatcagt ctaatattca aagtaccttt caagaacaac cactactgat agctgttttt
    22561 gcttgtgtca ttggacctct ggtagaagaa ttatttttcc gtcaggtctt attgcattac
    22621 ttgcaggaac ggttgccagg tttactaagc attattctgg taggacttgt ttttgctttg
    22681 actcatatgc acagtttggc tctatcagag tggattggtg cagttggtta cttaggtgga
    22741 ggccttgcct tttctattat ttatgtgaaa gaaaaagaga atatctacta tcccctactt
    22801 gttcacatgt taagcaacag cctctcctta atcattttag ctatcagtat agtaaaatga
    22861 aataagaaca ggacaaatca atcaggacag tcaaatcgat ttctaacaat gttttagaag
    22921 tagaggtgta ctattctagt ttcaatacac tgtaacatgt gatgaaaatg ccagtaatga
    22981 taccgagaaa aaagctgaga aacttttccc agctttattt gttatagtca aagcgaatga
    23041 cttgttcctg tgcatctaca tgagcatgga ccccaaaggg tacaattgct cttggagttg
    23101 cgtggccgac attcagatta tagacaatcg ggatattgct gtcaatgata tctaatagtg
    23161 cctctttata gtcgtcatgg aaagtttcat ccataggttt tccgaccaag agtccattga
    23221 tgaccgcgaa tatgccagtg tcctttaaag ttagcaacat ctttttgaag tcttctggct
    23281 taggcttttc ttcgcttgtt tcgagcaaga ggattttccc ttcccagtct gacaagtcag
    23341 ggaaaagttt gtattttggg cagagttccg tgctatctgc gtatcgagag ttgtcaaaga
    23401 tatcgtagag ggattcgagg caaccaccga ggattttccc ctcgaactga gcacttcctt
    23461 gcaacaagtc aaaacctgta tttgtatgac tgacacgagg tgttcccagg gccgtgggac
    23521 taaaatcagt tcgttcctca taccaaacgt cactagggcg gatttctgaa attcttcccg
    23581 tctcaatcaa ttctttaaag tagtgaaggc tataggctag catttctttg tctaattcac
    23641 aaatgtctgc taaaaaggat tgaccataaa aagtcttgat tcctaattta tgcaacatga
    23701 ggtggttcat ggttgtatcc gagaagccaa gaaaaatttt ttgcttgata accttttgga
    23761 gttggtcatt ttcaaaaaga taaggtagca agcgataggt atcgtctcca ccgatggcac
    23821 ataggatcat gtcgatgcta tcatcagaaa aggcatgaat caaatcctct gcacgagctt
    23881 caggatggtc cttgataaag tctaatcctt ttaacgaatg gggcaaaaag atgggattga
    23941 gtcccagatc cttgagacgt tggataccca agtccacttc gtgtttgaca aaatcctctc
    24001 cgataatgcc actagataaa ctaacaatac caatagtaga aaccatatct catcctccta
    24061 gaaatagatt gagcctattt tatcacaaaa tataagagaa agctatgtgg gatttcagaa
    24121 gaatactttt aatactcttc gaaaatctct tcaaaccacg tcagttttat ctgcaacctc
    24181 aaagctgtgc tttgagcaac ctgcagctag cttcctagtt tgctctttga ttttcattga
    24241 atataactca aaaaagtaag tgaaaaagca accgcacctg cagttgcttt tatcgttttc
    24301 ttattcttga tagcgtgttg gtcctgcact tgcactacgg atattcaagc gtttcttgag
    24361 atagaagcga agggctagga gggctgctcc aataatagct agtggcaatg gatccagtac
    24421 tgggttaagg ctagctggta ggaagcttgt tgcaaagaag acaagcaacc aaaggaacat
    24481 agaagctagg ataactagta cagatttcca gaaaggtgga cgttgactgc gatccatatc
    24541 tggtccatag tattggtaaa caaagtagta catcaagtag aaggcaaatc caccaaccag
    24601 tccaactaat agaagagtaa tcaatccata gccgaaagct tgatctgccg caaagaaggt
    24661 tgtgagggcg ctgacaaggg caaagaggct agtgatgaaa agagctgagt ccataatcat
    24721 cagttttgga tcatcatttt cttttggatg ctctttttcg tactgctctt tgacagtgaa
    24781 gctatgagcc caatgagttg gtgcgccgta tagggaacgg gcagttgtac ctttagattg
    24841 ctcctcaagg atttggggaa tgacttcctc aaaaatagtc tggatttcag cgtctgtttt
    24901 cccatctttg atgaattgtt gggtagcaat gtggacaaac tcttggtttt tcttagttaa
    24961 tttttgtaga tcaatttgag acataggaac tcctcttaga accatttttt atggatgaga
    25021 tagagagtga gcgagacact catagcaaag gcgataaaga cgattaacca gaaggcattt
    25081 ggctctccgt ttagggggat ttcattatcc ttaaagttca tcccgtaggc agaaaagacc
    25141 atggttggga tggacatgac gatggtcaca agggccaagg ttttcatgat gttgttctgg
    25201 ttgttagaaa tgatagaggc aaaggtctct gtcatagaat gcaagacgtt tccataaata
    25261 tctgccatct cgatggcctg ttgggtttca atcagggtgt cttcaagcag gtcttcgtcc
    25321 tcaaggtatt tcttgatatt gctggttgaa ctggtcaatt tcttaatcac gcgctcattt
    25381 gttttgaggg aggccttgaa atagacgata gttttttcca attccatgag ctcaatcaat
    25441 tcttcattac gagttgattg atgcagttga ctttcgattt gttcactctt gcggtcgatt
    25501 gaacgaaggg ctgttaggta aagctctgca ttgcgataaa gaatttgaaa gataaaacgt
    25561 gaacgcatga aggtatagaa attacgcaat cgacggttga taaagacatc aaggacaggt
    25621 agtggttcca aacacgtagt gataatggtt tcctcagtga tgataatacc aagcgggatg
    25681 gttacgtagt aggtgcggtt atttctttcc tccgtgaccg gcacgtctac gataatcagg
    25741 gtatactcgt cttcaatggt aatacgagac atttcttccg catcgagcgg tgctcgaagg
    25801 tcggcaatat caatatcgaa ggtgttggcg atttcgagtg attcattttg agtcggattg
    25861 acgagattga tccaagtacc cggttcaagc gtatcgatct ctttaaattc agttgttgta
    25921 gagagaaaaa cttgtttcat atcccttatc ctttctcatt tttcagattt tttcacactg
    25981 tactattata ctacaaaatc ggccttttgg gtaatagaat ctcacttttt ttggtataat
    26041 ggtaagcaat aatggactag aaagaacaaa gatgcaagat aaaattgtca ttcatggggc
    26101 gcgtgcccat aatttaaaaa atattgatgt ggagattccg cgagacaagc tggttgtcgt
    26161 gacaggtttg tcaggttcag ggaaatccag tctggccttt gataccctct atgcggaggg
    26221 acaacgtcgc tatgtagaga gtttgtcagc ctatgctcgt caattcttag gaaatatgga
    26281 gaaggcggat gtggatgcca ttgatggtct cagtccagct atttctatcg accagaaaac
    26341 gactagcaaa aaccctcgct cgacggtggg aacaacgact gaaatcaatg actatctgcg
    26401 tctcctctac gcacgtgtgg ggacgcctta ctgtatcaac ggacatggag ctatcaatgc
    26461 ttcttctgtg gagcaaatcg ttgataaggt tttggagtta cctgaacgcc agcgcttgca
    26521 gatcttggcc cctgtcatcc gcaagaaaaa aggccaacat aagagtgtta tcgagaaggt
    26581 tcagaaagac gggtatgttc gtgtccgtgt ggatggggaa gtctatgatg tgaccgaagt
    26641 gccagagttg tctaagagca agcaacacaa tatcgatgtc gtggttgacc gtattgttat
    26701 caaggagggc attcgtagtc gtctctttga ttccattgag gctgcccttc gtattgcaga
    26761 aggttatgtc attatcgaca ccatggacga ctctgagttg ttgttctctg agcattatgc
    26821 ctgtccagtt tgtggtttta ctgtcccaga gttagagcct cgtctcttct ctttcaatgc
    26881 tccttttggc tcttgtagtg agtgtgacgg cttgggcatc aagctggagg tggatactga
    26941 tttggtagtg ccagatgcca gcaaaacctt acgtgaggga gcgttagcac cttggaatcc
    27001 tatctcatcc aactactatc caaacatgtt agagcaggcc atgaaagtct ttggagtggc
    27061 tatggataag ccttttgagg acctgtcaga agaagataag aacttgattc tctatgggtc
    27121 agatggtaag gaattccatt tccactatga gaatgaattt ggtggcgtgc gcgatatcga
    27181 cattccgttt gagggagtta tcaataatat caaacgtcgt taccatgaaa ccaatagcga
    27241 ttacactcgc actcagatgc gtctctacat gaatgagctg acctgcggaa cctgtcaagg
    27301 ctatcgtctc aatgaccagg ccttgtctgt ccgtgtgggc ggccagcaag ggccacatat
    27361 tggagaaatc tcagacctgt ctatcgctga ccacttggac ttggtgagcc agttaacttt
    27421 gtctgaaaat gaagccatca ttgctcgtcc cattctcaag gaaatcaagg atcgtttgac
    27481 cttccttaat aatgtgggtc ttaactatct aaccctgtca cgttcagcag gaaccctttc
    27541 aggtggggaa agtcagcgca ttcgtttggc aacccagatt ggttccaacc tatcaggcgt
    27601 cctctatatc ctagacgagc cgtcaatcgg tcttcaccag agagacaatg accgcctgat
    27661 tgccagtctg aaaaagatgc gtgacttggg caatactctt atcgtggtgg aacacgacga
    27721 agataccatg cgtgaagctg attatctgat tgacgttggt cctggtgccg gtgtttttgg
    27781 tggtgagatt gttgcagcag gtacacctaa gcaagtggct cgcaacagca agtctatcac
    27841 aggtcagtac ttgtcaggca aacgtgtcat cccagtacca gaagagcgcc gtgtcggaaa
    27901 tggtcgtttt attgaagtga taggagcgcg tgagaacaac ttgcaaaatg tcacggctcg
    27961 ctttccacta ggaaaattta tcgcagtgac aggtgtgtcg ggttcaggga aatcgactct
    28021 aatcaacagc attcttaaaa aagccattgc ccagaagctc aaccgtaatt cagacaaacc
    28081 tggtaagttt aagactatta cagggattga gcatgtcgac cgtttgattg atattgacca
    28141 gagccctatc ggacggacgc cgaggtctaa cccagctacc tatacaggag tttttgacga
    28201 tatacgtgac ctttttgctc agacaaatga agccaagatt cgaggctaca agaaggggcg
    28261 cttcagtttc aacgtcaagg gaggtcgctg tgaagcttgc tcaggtgacg ggattatcaa
    28321 gattgagatg cacttcttgc cagatgttta tgtggcttgt gaagtttgcc acggaacccg
    28381 ctataacagt gaaaccctag aagttcacta caaggaaaag aatatttcgc aggtcttgga
    28441 tatgacggtc aacgatgcgg tagaattttt ccaacacatt ccgaaaattc aacgcaaact
    28501 ccagaccatc aaggatgtag ggctaggcta tgtgaccttg ggacagccag ctaccaccct
    28561 ttctggggga gaagcccaac gtatgaagtt agctagcgaa ctccacaaac gctcgacagg
    28621 aaaatctttc tacattctgg atgagccgac gacagggctt catacagagg acattgctcg
    28681 cctgctcaag gttttagctc gctttgtaga cgatggcaat acagtcctcg tcatcgagca
    28741 caatctggat gttatcaaga cggcagacca tatcattgac ttgggacctg agggcggtgt
    28801 cggtggtgga accatcatcg taacaggaac tccagaagaa gtagctgcca atgaagccag
    28861 ctatacagga cactatttga aaggaaagtt acatcatgaa taaacgcgta caagcatttc
    28921 tagctaaaat gcaagaaaaa gaactagatg gtatcatcat caacaatctt aaaaacgtct
    28981 attatttgac tggtttttgg ggctcaaacg gaacagtctt tatcagccgt gaccgtcagg
    29041 tcttagtgac agactctcgc tatatcatcg cagctaagca agaaaccagt ggttttgaga
    29101 ttgtggctga tcgtgatgaa ttggctgtca ttgcaggaat tgttaaggac atgggcttga
    29161 ctcgtatcgg ttttgaagat gagatttcag tatcttatta ccaccgtatg caggcagctt
    29221 ttgcaggttt ggacttgctt ccacaaactc aatttgtgga aggtcttcgt atgattaagg
    29281 atgaggcaga gattgcagcg attcgcaagg cttgttctat ctcagaccaa gctttccgcg
    29341 atgcgcttga ctttatcaaa ccaggaaaaa ctgaaattga aattgccaac ttccttgatt
    29401 tccgcatgcg tgagttggga gcatctagct tatcttttga tacgatccta gctagcggta
    29461 tcaattcttc taaaccccat gcccatccaa tgcacaaacc agtggagttg ggagaagcca
    29521 ttaccatgga cttcggctgt ctctatgacc actatgtcag tgatatgacc cggactatct
    29581 atctagggca tgttagcgat gagcaggcag agatttacaa tacggttcta aaagctaacc
    29641 aagccttgat tgaccaagct aaggcaggct taggtttccg tgactttgac aaaatccctc
    29701 gtgatattat cattgaggca ggttatggcg actactttac tcacggcatt ggccacggta
    29761 ttggtctgga tatccatgag gaaccctact ttagccagac ttctacagaa actattaaga
    29821 caggtatggc cttgaccgat gaaccaggta tctatatcga aggcaaatat ggcgttcgta
    29881 tcgaggatga tatcctgatt acagagacag gttgtgaatt attgacccta gctccaaaag
    29941 agttgatagt catttagttg tttgtcaaga aaaaagtacg aaaatgacga aaaaagtcaa
    30001 aaaaaattaa aaataggtcg caagtcggat gttttttatg gtataataga ctaaactgat
    30061 agtaacatgt agcgaaaggg gtaggtacat gattaaaatt tatacagtct caagttgtac
    30121 tagctgtaaa aaagcaaaaa cctggctcaa tgcccaccag ttaagttata aagaacaaaa
    30181 ccttggtaaa gaaggaatta cgagagaaga attactggat attctaacca aaacagataa
    30241 cggaatagcc agcatcgttt cgtctaaaaa tcgctatgcc aaagcccttg gagtggatat
    30301 tgaagatttg agtgtcaatg aagttctcaa tctgattatg gaaacaccga gaattttaaa
    30361 gagcccaatc cttgtagatg aaaaacgcct gcaagttggc tacaaggaag acgatattcg
    30421 tgccttccta ccacgctctg tccgtaatgt agaaaatgca gaagcacgtt tacgtgcagc
    30481 tctataaaca tcaaggctgg gagcacttcc cagtcttatt ctattttaat ttcaaaaaga
    30541 aagaagagag aaatgaaaaa aatagttctt gttagtctag ctttcctttt tgtcctggtt
    30601 ggttgcggac agaaaaaaga aactggaaca gctacaaaaa cagaaaagga tacgcttcag
    30661 tcggcattgc cagttattga aaatgccgag aagaatacag ttgtaaccaa gactttggtc
    30721 ttgcccaagt cagatgatgg tagccagcaa actcaaacca ttacatacaa ggacaagact
    30781 tttttgagct taacgattca acaaaaacgt ccagtttctg atgagttgaa gatttatatc
    30841 gaccaacatg gagtggaaga aactcaaaaa gctcttcttg aagcggagga gaaggataag
    30901 tctatcattg aagctcgtaa attggcaggt ttcaaacttg aaacaaaact attgagcgca
    30961 acggaacttc aaacaacgac tagttttgat tttcaagttc tggatgtcaa gaaggcttcc
    31021 cagttggaac atctgaagaa tattggtttg gaaaatcttt tgaaaaatga accaagcaaa
    31081 tatatttcag atagattggc aaatggcgcg acagaacaat agaaaatcca aataaataga
    31141 ctgcctgaat tgtagaaggt aaggaattat gctataatgg tactattcta aggaaagagg
    31201 gtgttagaat gggatttact gaagaaacag tacgttttaa attggacgat tccaataaaa
    31261 aagaaattag cgaaactttg acagatgttt atgcttcgtt gaacgataag ggttacaacc
    31321 caattaacca aatcgtaggt tacgtattga gtggagaccc tgcctacgtt cctcgttata
    31381 ataatgcacg aaatcaaatc cgtaagtatg agcgtgatga aatcgttgag gaattggttc
    31441 gctactacct aaaaggacaa ggagtcgatc tataacctat gagaattatg ggattggacg
    31501 tcggttcaaa aacggtaggg gtggcgatta gcgatccgct tggttttaca gctcaagggc
    31561 ttgaaatcat ccagataaat gaagaacaag gccaatttgg ttttgaccgc gttaaggaat
    31621 tggttgatac ttacaaggtg gaacgatttg tagtgggctt gcctaaaaac atgaacaata
    31681 caagtggacc gcgcgtagaa gctagtcaag cctacggagc aaagctagaa gagttttttg
    31741 gtttaccagt agactatcag gatgaacgct tgacaacagt ggctgctgag cgcatgttga
    31801 ttgaacaagc agatatcagt cgcaataagc gcaagaaagt cattgataag ttagcagctc
    31861 agctgatttt acaaaattat ttagatagaa aattttaata taaaggagag gctatgtcac
    31921 acgatcataa ccacgaccac gaagaacgtg aactaatcac actagtagat gagcaaggaa
    31981 atgaaacctt gtttgaaatc cttttgacaa ttgatggaaa agaagaattt ggtaaaaact
    32041 atgttcttct agtaccagtt aacgcagaag aagacgaaga cggacaagtt gaaatccaag
    32101 cttactcatt cattgaaaat gaagatggaa cagaaggcga attgcaacca atcccagaag
    32161 actcagaaga cgaatggaac atgattgaag aagtcttcaa cagctttatg gaggagtaaa
    32221 aacgtccggg ggacgttttt agccctgcgc tagaaattag aaacgcaggt agtctgggag
    32281 actgtatcag cccaactcca gaaatgggga agagttggaa cgtccagtga acatttttac
    32341 cccatattca cattcatagt agctagttat tagctaacca ggtaagaggt cgggacgaaa
    32401 atcctggcct tgtttttatt agtaaccata ctttaatgcg ataattgatt ggacttttgt
    32461 caaggagatg tgtatgtttg aagtagaaga atggctccat agtcggattg gtttgaattt
    32521 tcgatcaggt ttgggccgaa tgcagcaagc ggtggatttg ttaggaaatc ctgagcagtc
    32581 ttaccctatt atccacgtaa cagggactaa tgggaaagga tctaccattg cttttatgag
    32641 ggaattattt atggggcatg gcaaaaaagt tgcgaccttt acctcccctc atatcgtctc
    32701 tatcaatgac cgaatctgca ttaatgggca acctatagca gacgcagact ttatccgttt
    32761 gactgatcag gtcaaggaga tggagaaaac gcttctgcaa actcctgccc agttgtcctt
    32821 ttttgaattg ctgaccttag ttgcttttct ttattttagg gagcaagagg tggatttggt
    32881 tttattagaa gtgggaattg gtggcttact tgacacgacc aatgtggtaa ctggagagct
    32941 tgctgtcatc acctccattg ggcttgacca tcaagaaacc ttgggtgata gtctagaagc
    33001 aattgcagag cagaaagctg gtattttcaa ggctggtaag aaggcagtga ttgcgaaatt
    33061 gcctccagaa gctaggcttg tctgtcagaa aaaagccgaa tctttagctg ttaaccttta
    33121 tcaggcaggt caagattttt taatgctgaa tggtgatttt tcaagctctt tactaaatct
    33181 ttcacagctg aacataggct tagaaggagt ctatcagcag gagaatgcag ccttggcgtt
    33241 gcaaactttt cttcttttta tgggagaagg aaaggaagct gttgatgaac aggctgtaag
    33301 aaaggccttg gaacagaccc attgggctgg tcgcttggag cgtattcgcc cacagattta
    33361 cttggatggt gctcataacc tccctgcctt gactcgcttg gttgagttta tcaaagaaaa
    33421 agagcaggaa ggctatcgac ctcaaatcct ttttggagcc ttgaaacgga aggattatca
    33481 agggatgtta ggttacctga ctgaaaaatt gcctcaggtg gaactcaagg tgaccggctt
    33541 tgactatcag ggggctttgg acgaaaggga tgtgacaggt tacgatatag tttcttctta
    33601 ccgagaattt atcagcgatt ttgaagaaag agcagatgct caggatttgc tgttcgttac
    33661 agggtctctc tattttatct cagaagtacg gggctacctg ctggaccgtg agcagataaa
    33721 ttgaccccct tgtttgaact tgttatacta ggggaattgc tggttagaga aaatttctct
    33781 aaattggtag cagaaaggaa attcatcatg aaattaaaaa gattcacact ttctcttgct
    33841 tctctagcaa gttttagtct cttagtagct tgttcacaaa gagctcaaca ggttcaacag
    33901 cctgttgctc agcagcaggt ccaacagcct gctcaacaga ataccaatac tgcaaatgca
    33961 ggaggtaacc aaaatcaagc ggctccagta caaaaccaac ctgttgctca accgaccgat
    34021 attgatggga cttatactgg tcaggatgac ggagaccgta tcactttagt ggtaactgga
    34081 acgactggta catggactga gctcgaatct gacggggatc agaaagtcaa acaggttaca
    34141 tttgattcag caaatcaacg catgattatt ggcgatgatg tcaaaattta cactgtaaac
    34201 ggtaatcaaa tcgtcgtaga tgatatggat agagacccat cggaccaaat cgttttaact
    34261 aaataagact atgcaagtag aaagggctgg atttttcagc ctttttactt ttacctagaa
    34321 aataatcata aatacttgcc ttctaccgaa tacctgcgtt atactagtat caattacttg
    34381 tttttagcat tcaaactatc aaggagggga tatgaaatat aggaaatttc aattattgat
    34441 gtccaagtat ggctttagtc tttcgattat gctacttgaa ctttgtcttg tttttggtct
    34501 ctttctttat ttaggacgca tggctcccat tttatggatt actgtcctca ttctactgag
    34561 tatcatcaca atcatttcga tagtcaaccg taatacgact cctgagaata aggtaacctg
    34621 gttgttagta gcctttgtgc cagtatttgg tcccttgctc tatctgatgt ttggtgaaag
    34681 gcgattgtcc aaaaaagaaa tcaaacaact gaagaagcta ggctctatgc atttccaaga
    34741 agcaaatagc cagctactaa aagagaaatt aaaagaaagt gacaaggcag cttatggagt
    34801 catcaagtcc ttattgagta tggataccaa tgctgacatc tatgatcaaa ctgcctctac
    34861 attttttcct aacggagaag ctatgtggaa aaagatggta gaagatctta aaaaggctga
    34921 gaaatttatt ttcttggaat attacattat agaagaaggt ttgatgtgga atcgcatact
    34981 agatatacta gagcaaaagg tagctcaggg tgtagaggtt aagatgctct atgatgatat
    35041 cggctgtatg gctactttaa caggagatta tgcacatcga cttcgtcagc tgggcatcga
    35101 ggcccataaa ttcaataaag ttattcctcg tttgacagtg gcttataata acagagatca
    35161 tagaaaaata ttgattgttg atggtcagat agcctatact ggtggggtca atctggcaga
    35221 tgagtacatt aaccacgtcg agagatttgg ttattggaag gatagtggaa ttcgcttaga
    35281 cggactagca gtaaaagctc tgacacgctt atttttgacc acttggtaca ttaatcgagg
    35341 agaaattagt gattttgatc aatatcattt agaaaatcat tctatcccga gtgacggttt
    35401 aaccattcca tacggaagtg gacccaagcc aatttttcga gcgcaggtag ggaaaaaagt
    35461 ttatcagagt ttaatcaatc aagcaacaga atcggtctat attacgacac cttatttgat
    35521 tatagattat gatttaacag agacaatcaa aaatgcagct atgagagggg tcgatgttcg
    35581 aattatcacc ccttacatac cagataagaa gttcattcag ttagtcacga gaggagctta
    35641 tcccgacctt ctttctgctg gtgttcggat ttatgagtat agtccaggtt ttattcatag
    35701 taagcagatg ttggtagacg aagattttgc ggtggtgggg acaatcaatc tcgactaccg
    35761 gagcttggta caccattatg aaaatgcagt cttactctat aaaactcctt ctataaggga
    35821 aatcgcccga gattttcgaa atatatttgc agattctcag gaagtctatc ctcattctat
    35881 caaaacgagc tggtatcaaa agcttgtaaa agaaatcgcc cagctattcg cccctatctt
    35941 ataagaaatc tagaacttag gatacaaacc agacctattt ttcttgtctt ttacgaatag
    36001 aaagaaagag gaggggaatt catgctaact aaggaagaag tgaatgatat gattgagttc
    36061 aaacggacac atttacaccg ctttcgggaa attgaaacct ttgtgaaact atgcaaaaaa
    36121 tcactcaaac agccatcgca agctgacaat cctaggactt tttgatatac taagacagat
    36181 aaattgaaca ggagaaacga tatgagtgtg tatggtagag tagaagaagt tcataaggag
    36241 aatcgtgaac ctctagaata ccaaatcgaa caagaatcgc atcatcgtga atcaagtcgt
    36301 cttcctttgg tgaaaatttt actatggagt acgcttgtaa cggggataac tctaggagta
    36361 ccgctattac tcgacttaat gagtgcacaa gaagtgcagg atttttatgc aggttgggcg
    36421 cttcatcaga cagggaagat ttacagcgac tattatggaa gtcaaggttt gctttattat
    36481 ttgctgactt acgtgagtca gggcggattt ttctttgcca tctttgagtg gttagccttg
    36541 gtagcaggag gatttttcct ttttagatca gcggacacct tgacagagca aggagaccaa
    36601 gctggacatc tggtgactat tttttacatg ctagttacag gtcttgcttt tggtggaggc
    36661 tatgcgactc ttttagcgct tcctttctta ttcgcagcct ttagtttagt tgcggcttac
    36721 ctaagcaatc caagccatga taagggattt gtacggattg ggctagcttt ggcaggcgga
    36781 tttttctttg ctcccttatc atcgctcctg tttattgctg tagtgagttt aggcttgttg
    36841 gtctttaacc ttgggcatag acgttttgtg catgggtttt atcagtttct tgcagtggct
    36901 ttaggttttt cacttgtctt ttatccaact gcctactata gtgctgcaac aggaagtttt
    36961 ggggatgcga ttagtggtat tcgttatcct attgacagta ttcgctttga ttttacttct
    37021 aaaattttag agaatatgtt tttttatggc ttgttgtccc ttggtttggg atttgtggtt
    37081 tgtatctttt taggtctctt tcaatccaaa ccctttaaac tatacgtcat ttcggttcct
    37141 gcaagtcttg tggtaatttt aggtttgatt ttacttttct tttcacaaga gcctctgcac
    37201 gcttcttatt tgatggtcgt cttccctgtt ttcctacttt tattggtaac caatattaag
    37261 agtcaacaga gggggcgtag tgctagaaga agccgaagag aaacgccagt tagcctatgg
    37321 agtcgtttct tcaaaggaaa tctatatctg ctagtttttg ggtttgtcta tcttttgtct
    37381 gttccttttt tgatgaagtt tgtcctttat ccagtacctt atcaagaacg taatcgtctt
    37441 gctgatttgg taaaagagga gacaaatacg gaagatgcta tctatgcatg ggatgatact
    37501 gcgactcttt atcgtaagag tgagcgcttg tcgccatcgg cgattttgtc cccgttgcac
    37561 tatacagcaa ctgaagaaaa tcgtaataag ttacttaatg acttgaaaga aaaacaacct
    37621 aaggtgattg tggtaaatga caaggtggta gtctggtctg aagtggaaac actcttaaaa
    37681 gaaaattacc aacaagtaaa gactgattac tcagagttta aagtctataa aattaaataa
    37741 ccaaatcaat atcttgtgta tttttaaaaa ttttaggatt tttaacacaa gatattgatt
    37801 tttcttttta gagtggtata atacttttta gaaagaacat tttagaaaag agcatgcata
    37861 tgattgcact agaagaaaaa attacaattt tgccaactct cttcgtcgag aaacgagatg
    37921 ggagacgtgt tgtatttgat gtggacaaga ttgacaaggc tctccacaag gcggctgaca
    37981 aggttatgga tgtgacaccc ttggttgaaa aacgcctcaa tgatctgact gagcgaatta
    38041 ttacagaaat tcatagtcgc tttccacagg gaattaagat ttacgaaatt caaaatatcg
    38101 tagaacatga actccttgaa gccaaagaat atgcgctggc tgaggagtat attacttatc
    38161 ggacacagag ggattttgag cgctcaaaag cgacggatat caactttagt attcataaac
    38221 ttctcaacaa agaccagaca gttgtcaatg aaaatgctaa taaagacagt gatgtcttta
    38281 acactcagcg tgatttgaca gcagggattg ttgggaaatc aatcggactg caaatgcttc
    38341 ctaagcacgt agccaatgcc caccaaaagg gggatatcca ctatcacgat ttggactaca
    38401 gtccctatac ccctatgacc aactgctgtt tgattgattt taagggtatg ttggaaaatg
    38461 gttttaagat tggaaatgca gaggtagaga gtcccaagtc tatccagact gcgacagcac
    38521 agatttctca aatcattgcc aacgttgctt ctagccagta cggtggctgt tcagctgacc
    38581 gtatcgatga aattttggcg ccttatgcag agaagaacta tcaaaaacat ctcaaagatg
    38641 cagaagagtg ggtattgcct gaaaaacggg aagattacgc ttggaagaaa acgcaaaagg
    38701 acatctacga tgccatgcaa tctcttgagt atgaaatcaa tactctcttc acttcaaatg
    38761 gacaaacacc ttttacttcg ttaggttttg gtctgggaac cagtcgtttt gaacgagaaa
    38821 ttcaaaaagc tattttaaac attcgcatca agggtcttgg ttcagaacac cgtacggcta
    38881 tctttcctaa acttattttc actctgaaaa gaggccttaa tttagaggaa ggaactccca
    38941 actacgacat caagcagttg gctcttgagt gtgcaaccaa acggatgtat ccagatgttt
    39001 tatcttacga taagattgtt gacttgacag gatccttcaa ggtgcctatg ggttgccgtt
    39061 ctttcctcca aggatggaag gatgaaaatg gtgtagaagt caattcaggt cgcatgaatc
    39121 tgggtgttgt gacggttaat ctgcctcgta ttgctcttga gtctgaaggt gatatgaata
    39181 agttctggga aatcttcaac gagcgaatga atatcgcaga agatgctctt gtttaccgtg
    39241 tcgaacgcac taaagaggcg acaccagcga atgctcctat tctttatcag tacggtgctt
    39301 ttggccatcg tctaggtaaa gaagaaagtg ttgaccagct ctttaagaat cgtcgtgcga
    39361 ccgtttcgct gggctatatc ggcttgtatg aagtagcgac agttttcttt ggtaacagct
    39421 gggaaagtaa tccagatgct aaggaattca cgctagacat cattcacgat atgaaacgcc
    39481 gtgtagaaga gtggtcagac caatatggct accatttctc tatctactca acaccatccg
    39541 aaagtctgac agaccgtttc tgccgactag atatagacaa gtttggctct attcctgata
    39601 tcacagacaa ggaatactac accaactctt tccactacga tgttcgtaaa aatccaacac
    39661 cgtttgaaaa attggacttt gagaaagtct atccagaagc aggtgcgtca ggtggtttca
    39721 tccattattg tgagtatcca gtccttcagc aaaatccaaa ggccttggaa gctgtctggg
    39781 attatgctta tgaccgtgta ggctatctag gcaccaatac tccgattgac cgttgctaca
    39841 agtgtgactt tgaaggggat tttgaaccaa ctgagagagg gtttgcttgt ccaaactgtg
    39901 gcaatagcga tcctaaaaca gtagacgttg ttaaacggac ttgtggctat cttggcaatc
    39961 ctcaagcgag accgatggtt aacgggcgtc acaaggaaat cgctgcgcgt gtcaaacata
    40021 tgaatggttc aacgattaaa atagctgggc atcaagtaac aaattagaaa gaaatgaaat
    40081 gggaaaatat caactagacg ataaggggcg cgcacaagtg acccgttatc acgagaaata
    40141 ctctaaaggt ggagctggta agaaagaacg cttgcttagc ttcagagaac aatttttaaa
    40201 caagaacaag aaaaaataaa agtgagagcc agctctcgct tttctcatag tgggaggtag
    40261 ggatggaatt acgcagacca agattagcgg ataagaaagc tgttttagat atgatgacag
    40321 agtttgaaaa gagccaatca gcccatgatg gaggattttg ggatacagag aactttgtgt
    40381 atgaagagtg gttggaaagc aatcaggaac aggaaatggg gattaatctg cctgaaggat
    40441 gggttcctgc aattcagtta gtggcttttt ctgagaaagg tcaagcagtt ggatttctta
    40501 atctccggtt gcgcctcagt aactttctac tagaagaagg tgggcacatt ggctactcca
    40561 tccgtccatc tgaaagaggc aagggttatg caaaagagac tctccgtcag ggcttgcaag
    40621 ttgctaagga aaagaacatc aagaaagctc tggtgacctg tagcgtgaat aatcctgcta
    40681 gcagagcagt cattctagca aatggtggaa tatttgagga tgctcgcaat ggagtcgagc
    40741 gttattggat agaggtagcg aatgaataat ccaaaaccac aagaatggaa aagcgaggaa
    40801 cttagtcaag gtcgtatcat tgactacaag gcctttaact ttgttgatgg cgaaggcgtg
    40861 cgtaactctc tctatgtagc aggctgtatg tttcactgcg agggatgtta taatgttgcg
    40921 acttggtctt ttaatgctgg cattccctat acagcagaat tagaagagca gatcatggca
    40981 gatcttgctc agccctatgt tcaaggtttg actttgttgg gaggggagcc ttttctcaat
    41041 actggcattc tcttgccact tgttaagcgg attcggaaag aattgtcaga caaggacatc
    41101 tggtcctgga ccggctacac ttgggaagaa atgatgttgg aaactccaga taaactggaa
    41161 ctcttgtcac tgattgatat tcttgtcgat ggaagatatg atcgaactaa gagaaatctt
    41221 atgctccagt ttcgaggttc gtctaaccaa cgaattatcg atgtgcaaaa atcgctcaaa
    41281 agtgggcaag tagtgatttg ggacaagctc aatgacggaa aagaaagcta tgaacaggtg
    41341 aagagagaat gaagaaaaaa gacttagtag accaactagt ctcagagatc gagacgggga
    41401 aagtcaggac actgggaata tacggtcatg gagcttcagg taaatcaacc cttgcacagg
    41461 aattgtccca agctttagat tctactacag taaatttgct agaaacagat ccctatatca
    41521 cctccggacg ctatttggta gtacccaagg acgcgccgaa tcaaaaggtg acagccagtc
    41581 tgccagtggc gtatgaactg gagagtttgc agagagatat ccttgccttg caggcgggta
    41641 tggatgtctt gacaattgaa gaaccttgga aggctagtga agtcttgtct ggagccaaac
    41701 caattttgat tgtcgaaggg atgtctgttg gttttctacc caaggaactc tttgaaaaaa
    41761 ccatctgttt ctacacggat gaggagaccg aattaaagcg acgctttgct agagatacga
    41821 ctgtgagaaa tcgcgatgca tcctttatat tggctagcca tcagatgaga cgggagcagt
    41881 atctgcgata ctataaagaa actgagtcta aggcggatat cttagtggac caatcagaag
    41941 ataaatttga tgtcaagagg acttaactta tgtatagaag aaaatcccta attttagaaa
    42001 gaaaaagtag gaaaacagtt tcatcccaaa aaaacgaaaa aacctaacaa atcccttgca
    42061 atcgcagggg atttgtgtta ttctattatg gtgctgtaaa ttacagcctt agttttgatg
    42121 caagaggttg cgacacgctc ggttgcattg ccacgcaaca ccgcgtcggt tttcttgtgg
    42181 agctagccta ttatcttaaa tagacgaaaa ggagaaaaag atggcaaaca aaaaaatccg
    42241 tatccgtttg aaagcttacg aacaccgtac gcttgacaca gcggctgcaa aaatcgtaga
    42301 atcagctact cgtacaggtg cacaagttgc gggtccaatc ccacttccaa ctgaacgtag
    42361 cctctacaca atcattcgtg cgactcacaa atacaaagac tctcgcgaac aatttgaaat
    42421 gcgtacacac aaacgtttga tcgatatcgt taacccaact caaaaaacag ttgatgcctt
    42481 gatgaaattg gatcttccaa gtggtgtaaa cgtagaaatc aaactttaat ctaaaatata
    42541 aaagagcaga ggctggtgtt tcaatctaat tgaacacggg ctaaactcgg tgtgaaaaag
    42601 ataaacttcc tagtgtctgc tagacactgc gtcagtttcc tattttcacg ttgagtttga
    42661 cgccctttgt atcttagact tgagcataaa aaacgctcgt taaaaacttt ttgaataaaa
    42721 atatagaaaa ggaactattt tctcatgaca aaaggaatct tagggaaaaa agtgggaatg
    42781 actcaaatct tcactgaagc tggcgaattg atccctgtaa cagttattga agcaactcca
    42841 aacgttgttc ttcaagttaa aactgttgaa acagacggat acaacgctat ccaagttggt
    42901 ttcgatgaca aacgcgaagt attgagcaac aaacctgcta aaggacatgt agcgaaagct
    42961 aacacggctc ctaagcgctt cattcgtgaa ttcaaaaacg ttgaaggctt ggaagttggt
    43021 gctgaaatta cagttgaaac attcgcagct ggagacgttg ttgacgtaac tggtacttct
    43081 aaaggtaaag gtttccaagg tgttatcaaa cgccacggac aatcacgtgg accaatggct
    43141 cacggttctc gttaccaccg tcgtccaggt tctatgggac ctgttgcacc taaccgcgta
    43201 ttcaaaggta aaaaccttgc aggacgtatg ggtggtgacc gcgtaacaat tcaaaatctt
    43261 gaagttgtac aagttgttcc agaaaagaac gttatcctta tcaaaggtaa cgtaccaggt
    43321 gctaagaaat ctcttatcac tatcaaatca gcagttaaag ctggtaaata ataaagaaag
    43381 gggaaatcag tcacaatggc aaacgtaaca ttatttgacc aaactggtaa agaagctggc
    43441 caagttgttc ttagcgatgc agtatttggt atcgaaccaa atgaatcagt tgtgtttgat
    43501 gtaatcatca gccaacgcgc aagccttcgt caaggaacac acgctgttaa aaaccgctct
    43561 gcagtatcag gtggtggacg caaaccatgg cgtcaaaaag gaactggacg tgctcgtcaa
    43621 ggttctatcc gctcaccaca atggcgtggt ggtggtgttg tcttcggacc aactccacgt
    43681 tcatacggct acaaacttcc acaaaaagtt cgtcgcctag ctcttaaatc agtttactct
    43741 gaaaaagttg ctgaaaacaa attcgtagct gtagacgctc tttcatttac agctccaaaa
    43801 actgctgaat ttgcaaaagt tcttgcagca ttgagcatcg attctaaagt tcttgttatc
    43861 cttgaagaag gaaatgaatt cgcagctctt tcagctcgta accttccaaa cgtgaaagtt
    43921 gcaactgcta caactgcaag tgttcttgac atcgcaaata gcgacaaact tcttgtcaca
    43981 caagcagcta tctctaaaat cgaggaggtt cttgcataat gaatttgtat gatgttatca
    44041 aaaaacctgt catcactgaa agctcaatgg ctcaacttga agcaggaaaa tatgtatttg
    44101 aagttgacac tcgtgcacac aaacttttga tcaagcaagc tgttgaagct gctttcgaag
    44161 gtgttaaagt tgccaatgtt aacacaatca acgtaaaacc aaaagctaaa cgtgttggac
    44221 gttacactgg ttttactaac aaaactaaaa aagctatcat cacacttaca gctgattcta
    44281 aagcaatcga gttgtttgct gctgaagctg aataatctaa ggaggaaata tcgtgggaat
    44341 tcgtgtttat aaaccaacaa caaacggtcg ccgtaatatg acttctttgg atttcgctga
    44401 aatcacaaca agcactcctg aaaaatcatt gcttgttgca ttgaagagca aggctggtcg
    44461 taacaacaac ggtcgtatca cagttcgtca ccaaggtggt ggacacaaac gtttctaccg
    44521 tttggttgac ttcaaacgta ataaagacaa cgttgaagca gttgttaaaa caatcgagta
    44581 cgatccaaac cgttctgcaa acatcgctct tgtacactac actgacggtg tgaaagcata
    44641 catcatcgct ccaaaaggtc ttgaagtagg tcaacgtatc gtttcaggtc cagaagcaga
    44701 tatcaaagtc ggaaacgctc ttccacttgc taacatccca gttggtactt tgattcacaa
    44761 catcgagttg aaaccaggtc gtggtggtga attggtacgt gctgctggtg catctgctca
    44821 agtattgggt tctgaaggta aatacgttct tgttcgtctt caatcaggtg aagttcgtat
    44881 gattcttgga acttgccgtg ctacagttgg tgttgtcgga aacgaacaac atggacttgt
    44941 aaaccttggt aaagcaggac gtagccgttg gaaaggtatc cgcccaacag ttcgtggttc
    45001 tgtaatgaac cctaacgatc acccacacgg tggtggtgaa ggtaaagcac cagttggtcg
    45061 taaagcacca tctactccat ggggcaaacc tgctcttggt cttaaaactc gtaacaagaa
    45121 agcgaaatct gacaaactta tcgttcgtcg tcgcaacgag aaataatatt aaactagtcg
    45181 cttaagcaac tagtaaatcc gccagctcgg tagcgctcca taggagtgca agccgctgtg
    45241 gtacaacatt taaaggagaa aatataaaaa tgggacgcag tcttaaaaaa ggacctttcg
    45301 tcgatgagca tttgatgaaa aaagttgaag ctcaagctaa cgacgaaaag aaaaaagtta
    45361 ttaaaacttg gtcacgtcgt tcaacgatct tcccaagttt cattggttac actattgcag
    45421 tttatgacgg acgtaaacac gtacctgttt acatccaaga agacatggta ggccacaaac
    45481 ttggtgaatt tgcaccaact cgtacttaca aaggtcacgc tgcagacgac aagaaaacac
    45541 gtagaaaata aggagaacat aaatggcaga aattacttca gctaaagcaa tggctcgtac
    45601 agtacgtgtt tcacctcgta aatcacgtct tgttcttgat aacatccgtg gtaaaagcgt
    45661 agccgatgca atcgcaatct tgacattcac tccaaacaaa gctgctgaaa tcatcttgaa
    45721 agttttgaac tcagctgtag ctaacgctga aaacaacttt ggtttggata aagctaactt
    45781 ggtagtatct gaagcattcg caaacgaagg accaactatg aaacgtttcc gtccacgtgc
    45841 gaaaggttca gcttcaccaa tcaacaaacg tacagctcac atcactgtag ctgttgcaga
    45901 aaaataagga ggtaaaatcg tgggtcaaaa agtacatcca attggtatgc gtgtcggcat
    45961 catccgtgat tgggatgcca aatggtatgc tgaaaaagaa tacgcggatt accttcatga
    46021 agatcttgca atccgtaaat tcgttcaaaa agaacttgct gacgcagcag tttcaactat
    46081 tgaaatcgaa cgcgcagtaa acaaagttaa cgtttcactt cacactgcta aaccaggtat
    46141 ggttatcggt aaaggtggtg ctaacgttga tgcactccgt gcaaaactta acaaattgac
    46201 tggaaaacaa gtacacatca acatcatcga aatcaaacaa cctgatttgg atgctcacct
    46261 tgtaggtgaa ggaattgctc gtcaattgga gcaacgtgtt gctttccgtc gtgcacaaaa
    46321 acaagcaatc caacgtgcaa tgcgtgctgg agctaaagga atcaaaactc aagtatcagg
    46381 tcgtttgaac ggtgcagata tcgcccgtgc tgaaggatac tctgaaggaa ctgttccgct
    46441 tcacacactt cgtgcagata tcgattacgc ttgggaagaa gcagatacta catacggtaa
    46501 acttggtgtt aaagtatgga tctaccgtgg tgaagttctt ccagctcgta aaaacactaa
    46561 aggaggtaaa taaccaatgt tagtacctaa acgtgttaaa caccgtcgtg aattccgtgg
    46621 aaaaatgcgc ggtgaagcaa aaggtggaaa agaagtagca ttcggtgaat acggtcttca
    46681 agctacaact agccactgga tcactaaccg ccaaatcgaa gctgctcgta tcgccatgac
    46741 tcgttacatg aaacgtggtg gtaaagtttg gattaaaatc ttcccacaca aatcatacac
    46801 tgctaaagct atcggtgtgc gtatgggatc tggtaaaggg gcacctgaag gttgggtagc
    46861 accagttaaa cgtggtaaag tgatgttcga aatcgctggt gtatctgaag agattgcacg
    46921 tgaagcgctt cgacttgcta gccacaaatt gccagttaaa tgtaaattcg taaaacgtga
    46981 agcagaataa ggagaaggca tgaaacttaa tgaagtaaaa gaatttgtta aagaacttcg
    47041 tggtctttct caagaagaac tcgcgaagcg cgaaaacgaa ttgaaaaaag aattgtttga
    47101 acttcgtttc caagctgcta ctggtcaatt ggaacaaaca gctcgcttga aagaagttaa
    47161 aaaacaaatc gctcgtatca aaacagttca atctgaagcg aaataataga ctagggaagg
    47221 agaaatttca atggaacgca ataatcgtaa agttcttgtt ggacgtgttg tatctgacaa
    47281 aatggacaag acaatcacag ttgtagttga aacaaaacgt aaccacccag tctatggtaa
    47341 acgtattaac tactctaaaa aatacaaagc tcatgatgaa aacaatgttg ccaaagaagg
    47401 tgatatcgta cgtatcatgg aaactcgccc gctttcagct acaaaacgtt tccgtcttgt
    47461 agaagttgtt gaagaagcgg tcatcatcta atcaaacctg aaaggagaaa actgaaatga
    47521 ttcaaacaga aactcgtttg aaagtcgcag acaacagcgg tgctcgcgaa atcttgacta
    47581 tcaaagttct tggtggttca ggacgtaaat ttgcaaacat cggtgatgtt atcgtggcat
    47641 ctgtaaaaca agctactcct ggtggtgcgg ttaaaaaagg tgacgttgtt aaagcagtta
    47701 tcgttcgtac taaatcaggt gctcgtcgtg ctgatggttc atacatcaaa tttgacgaaa
    47761 acgcagcagt tatcatccgt gaagacaaaa ctcctcgcgg aacacgtatc tttggcccag
    47821 ttgcacgtga attgcgtgaa ggtggtttca tgaagatcgt gtcacttgct ccagaagtac
    47881 tttaattttt aggaacaaac tagtccccta gcttcaagct agggtgccct tatgggcgta
    47941 agaaaaatca aggagaaacc taatgtttgt aaaaaaaggc gacaaagttc gcgtaatcgc
    48001 tggtaaagat aagggaacag aagctgttgt ccttactgcc cttccaaaag taaacaaagt
    48061 tatcgttgaa ggtgttaaca ttgttaagaa acaccaacgt ccaactaacg agcttcctca
    48121 aggtggtatc atcgagaaag aagcagctat ccacgtatca aatgttcaag ttttggacaa
    48181 aaatggtgta gctggtcgtg ttggttacaa atttgtagac ggtaaaaaag ttcgctacaa
    48241 caaaaaatca ggcgaagtgc ttgattaatc acgaaggaaa ggagaagtat aatggcaaat
    48301 cgtttaaaag aaaaatatct taatgaagta gttcctgctt tgacagaaca attcaactac
    48361 tcatcagtga tggctgtgcc taaagtagat aagattgttt tgaacatggg tgttggtgaa
    48421 gctgtatcaa acgctaaaag ccttgaaaaa gctgctgaag aattggcact tatctcaggt
    48481 caaaaaccac ttatcactaa agctaaaaaa tcaatcgccg gcttccgtct tcgtgaaggt
    48541 gttgcgatcg gtgcaaaagt tacccttcgt ggtgaacgta tgtacgaatt cttggataaa
    48601 ttggtatcag tttcacttcc acgtgtacgt gacttccacg gtgtcccaac aaaatcattt
    48661 gatggacgcg ggaactacac acttggtgtg aaagaacaat taatcttccc agaaatcaac
    48721 ttcgatgacg ttgacaaaac tcgtggtctt gacatcgtta tcgtaacaac tgctaacact
    48781 gacgaagagt cacgtgcatt gcttacaggc cttggaatgc cttttgcaaa ataatatagg
    48841 aggtaaatct aatggctaaa aaatcaatgg tagctagaga ggctaaacgc caaaaaattg
    48901 ttgaccgtta tgctgaaaaa cgtgctgcat taaaggcggc aggggactac gaaggtttat
    48961 ctaaattacc tcgcaacgcc tcaccgactc gtttacataa tcgttgtaga gttacggggc
    49021 gcccacattc agtttaccgc aaatttggtc tgagtcgtat cgcttttcgc gaacttgcgc
    49081 ataaaggtca aattcctggt gtaacaaaag catcttggta atttaagata tcaagggtgt
    49141 caaaactcca agtaaaaata ggaaacttga cgaagaaact aaagtttcta ggaaagttta
    49201 tctttttcac acagagttta gcccgggttc aattgggctt gccaatttga acccgagcta
    49261 cagctttggc aaaaaagacc aatttgcttt ggagcattgc ttctgcatta aattgtctat
    49321 ttttgctcgt gctgttacgc tctttgtatc atgtattaac tagcaagtgc aacttgcaaa
    49381 ctactagtaa gaggagaaaa acaaaatggt tatgactgac ccaatcgcag acttcctaac
    49441 tcgtattcgt aatgctaacc aagctaaaca cgaagtactt gaagtacctg catcaaacat
    49501 caaaaaaggg attgctgaaa tccttaaacg cgaaggtttt gtaaaaaacg ttgaaatcat
    49561 tgaagatgac aaacaaggcg tcatccgtgt atttcttaaa tacggatcaa atggtgagaa
    49621 agttatcact aacttgaaac gtgtttctaa accaggactt cgtgtctaca aaaaacgtga
    49681 agaccttcca aaagttctta acggacttgg aattgccatc ctttcaactt ctgaaggttt
    49741 gcttactgat aaagaagcac gccaaaagaa tgttggtggt gaggttatcg cttacgtttg
    49801 gtaaaatcaa gatacaaagc tcgtaaagaa caaagcaaaa ttaggaagtt ggagaagttt
    49861 gtttacaaac aagccaactt atctattttg cacagttctt agagcgtgtt cagttcagct
    49921 cttgaactaa ataagtatct gaaccccgtg aaaactggcc gttctggcct gacaatttaa
    49981 caggagaaaa taaacatgtc acgtattggt aataaagtta tcgtgttgcc tgctggtgtt
    50041 gaactcgcta acaatgacaa cgttgtaact gtaaaaggac ctaaaggaga acttactcgt
    50101 gagttctcaa aagatattga aatccgtgtg gaaggtactg aaataactct tcaccgtcca
    50161 aacgattcaa aagaaatgaa aactatccac ggaactactc gtgccctttt gaacaacatg
    50221 gttgttggtg tatcagaagg attcaagaaa gaacttgaaa tgcgtggggt tggttaccgt
    50281 gcacagcttc aaggatctaa acttgttttg gctgttggta aatctcatcc agacgaagtt
    50341 gaagctccag aaggaattac ttttgaactt ccaaacccaa caacaatcgt tgttagcgga
    50401 atttcaaaag aagtagttgg tcaaacagct gcttacgtac gtagccttcg ttcaccagaa
    50461 ccatataaag gtaaaggtat ccgttacgtt ggtgaattcg ttcgccgtaa agaaggtaaa
    50521 acaggtaaat aatgttgagt ggttgatcat caaccaccaa cctattttcc aactttgtgc
    50581 atagcacacg atttaaaact aaagaggtga aaactgtgat ttcaaaacca gataaaaaca
    50641 aactccgcca aaaacgccac cgtcgcgttc gcggaaaact ctctggaact gctgatcgcc
    50701 cacgtttgaa cgtattccgt tctaatacag gcatctacgc tcaagtgatt gatgacgtag
    50761 cgggtgtaac gctcgcaagt gcttcaactc ttgataaaga agtttcaaaa ggaactaaaa
    50821 ctgaacaagc cgttgctgtc ggtaaactcg ttgcagaacg tgcaaacgct aaaggtattt
    50881 cagaagtggt gttcgaccgc ggtggatatc tatatcacgg acgtgtgaaa gctttggctg
    50941 atgcagctcg tgaaaacgga ttgaaattct aataggagga cactagaaaa tggcatttaa
    51001 agacaatgca gttgaattag aagaacgcgt agttgctgtc aaccgtgtta caaaagttgt
    51061 taaaggtgga cgtcgtcttc gtttcgcagc tcttgttgtt gttggtgacc acaatggtcg
    51121 cgtaggattt ggtactggta aagctcaaga agttccagaa gcaatccgta aagcagtaga
    51181 tgatgctaag aaaaacttga tcgaagttcc tatggttgga acaacaatcc cacacgaagt
    51241 tctttcagaa ttcggtggag ctaaagtatt gttgaaacct gctgtagaag gttctggagt
    51301 tgccgctggt ggtgcagttc gtgccgttgt ggaattggca ggtgtggcag atattacatc
    51361 taaatcactt ggttctaaca ctccaatcaa cattgttcgt gcaactgttg aaggtttgaa
    51421 acaattgaaa cgcgctgaag aaattgctgc ccttcgtggt atttcagttt ctgatttggc
    51481 ataagaaagg ggataaaatg gctcaaatta aaattacttt gactaagtct ccaatcggac
    51541 gcattccatc acaacgtaaa actgttgtag cacttggact tggcaaattg aacagctctg
    51601 ttattaaaga agataacgct gctatccgtg gtatgattac agcagtatct cacttagtaa
    51661 cagttgaaga agtaaactaa tgaagtttta ggggatgtgc actgtaccat cccctaaaac
    51721 tagatatagt catctatgat gacatcgtat aggcgagttg atgggggaga caaccttttc
    51781 tcccttatcg gcgctagcat tttacaaaag aggagaaaat aaaaatgaaa cttcatgaat
    51841 tgaaacctgc agaaggttct cgtaaagtac gtaaccgcgt tggtcgtggt acttcatcag
    51901 gtaacggtaa aacatctggt cgtggtcaaa aaggtcaaaa agctcgtagc ggtggcggag
    51961 ttcgccttgg ttttgaaggt ggacaaactc cattgttccg tcgtcttcca aaacgtggat
    52021 tcactaacat caacgctaaa gaatacgcaa ttgtgaacct tgaccaattg aacgtctttg
    52081 aagatggtgc tgaagtaact ccagttgttc ttatcgaagc aggaattgtt aaagctgaaa
    52141 agtcaggtat taaaattctt ggtaacggtg agttgactaa gaaattgact gtgaaagcag
    52201 ctaaattctc taaatcagct gaagaagcta tcactgctaa aggtggttca gtagaagtca
    52261 tctaagagag gtgacctatg ttttttaaat tattaagaga agctcttaaa gtcaagcagg
    52321 ttcgatcaaa aattttattt acaattttta tcgttttggt ctttcgtatc ggaactagca
    52381 ttacagttcc tggtgtgaat gccaatagct tgaatgcttt aagtggatta tccttcttaa
    52441 acatgttgag cttggtgtcg gggaatgccc taaaaaactt ttcgattttt gccctaggag
    52501 ttagtcccta tatcaccgct tctattgttg tccaactctt gcaaatggat attttaccca
    52561 agtttgtaga gtggggtaaa caaggggaag taggtcgaag aaaattgaat caagctactc
    52621 gttatattgc tctagttctc gcttttgtgc aatctatcgg gattacagct ggttttaata
    52681 ccttggctgg agctcaattg attaaaactg ctttaactcc acaagttttt ctgacgattg
    52741 gtatcatctt aacagctggt agtatgattg tcacttggtt gggtgagcaa attacagata
    52801 agggatacgg aaacggtgtt tccatgatta tctttgccgg gattgtttcc tcaattccag
    52861 agatgattca gggcatctat gtggactact ttgtgaacgt cccaagtagc cgtatcactt
    52921 catctatcat tttcgtaatc attttgatta ttactgtatt gttgattatt tactttacaa
    52981 cttatgttca acaagcagaa tacaaaattc caatccaata tactaaggtt gcacaaggtg
    53041 ctccatctag ctcttacctt ccgttaaagg taaaccctgc tggagttatc cctgttatct
    53101 ttgccagttc gattactgca gcgcctgcgg ctattcttca gtttttgagt gccacaggtc
    53161 atgattgggc ttgggtaagg gtagcacaag agatgttggc aactacttct ccaactggta
    53221 ttgccatgta tgctttgttg attattctct ttacattctt ctatacgttt gtacagatta
    53281 atcctgaaaa agcagcagag agcctacaaa agagtggtgc ctatatccat ggagttcgtc
    53341 ctggtaaagg tacagaagaa tatatgtcta aacttcttcg tcgtcttgca actgttggtt
    53401 ccctcttcct tggtgtgatt tccattttac cgattgcagc taaagatgta tttggtcttt
    53461 ctgatgttgt tgcctttggt ggaacaagtc tcttgatcat tatctctaca ggtatcgaag
    53521 gaatcaagca attggaaggt tacctattga aacgtaagta tgttggtttc atggacagaa
    53581 cagaataaaa gtatttactg aatcagtaaa tactgaggga gtggaggttt aaactctgac
    53641 atttgtaaga gttggatctc ccctcttcta ttttgttttt aaataggggt gaaaagactt
    53701 tttgcttcta tttaaaaata aaataaggag atcaaatcat gaatcttttg attatgggct
    53761 tacctggtgc aggtaaggga actcaagcag caaaaatcgt agaacaattc catgttgcac
    53821 atatctcaac aggtgatatg ttccgcgctg caatggcaaa tcaaactgaa atgggtgttc
    53881 ttgctaagtc atatattgac aagggtgaat tggttcctga cgaagttaca aatggaatcg
    53941 taaaagaacg cctttcacaa gatgatatta aagaaacagg attcttattg gatggttacc
    54001 cacgtacaat tgaacaagct catgccttgg acaaaacatt ggctgaactt ggcattgaac
    54061 tagaaggtgt tatcaatatt gaagtgaacc ctgacagcct cttggaacgt ttgagtggcc
    54121 gtatcatcca ccgcgtaact ggagaaactt tccacaaggt ctttaaccca ccagttgact
    54181 ataaagaaga agattactac caacgtgaag atgataagcc tgagacagta aaacgtcgtt
    54241 tggatgttaa tattgctcaa ggagaaccaa tcattgctca ctaccgtgcc aaaggtttgg
    54301 ttcatgacat cgaaggtaat caagatatca atgatgtctt ctcagatatt gaaaaagtat
    54361 tgacaaattt gaaataaagc gtttttcaca cttgcaaaaa tccgctacaa atgttatact
    54421 gagatagtct gacttataat tgttgtctct gtgtctagag gcatcgaatc gaaatttatg
    54481 gaggtgcttt tgcgtggcaa aagacgatgt gattgaagtt gaaggcaaag tagttgatac
    54541 aatgccgaat gcaatgttta cggttgaact tgaaaatgga catcagattt tagcaacagt
    54601 ttctggtaaa attcgtaaaa actatattcg tattttagcg ggagatcgtg ttactgtcga
    54661 aatgagtcca tatgacttga cacgtggacg tatcacttac cgctttaaat aatcgaaaaa
    54721 cttggaggga taagaaatga aagtaagacc atcggtcaaa ccaatttgcg aatactgtaa
    54781 agttattcgt cgtaatggtc gtgttatggt aatttgccca gcaaatccaa aacacaaaca
    54841 acgtcaagga taagatagaa aggagaaaac atggctcgta ttgctggagt tgatattcca
    54901 aatgacaaac gcgtagtaat ctcattgact tatgtttatg gtatcggact tgcaacatct
    54961 aagaaaattt tggctgctgc tggaatctca gaagatgttc gtgtacgtga tcttacatca
    55021 gatcaagaag atgctatccg tcgtgaagtg gatgcaatca aagttgaagg tgaccttcgt
    55081 cgtgaagtaa acttgaacat caaacgtttg atggaaatcg gttcataccg tggtatccgt
    55141 caccgtcgtg gacttcctgt ccgtggacaa aacactaaaa acaacgctcg cactcgtaaa
    55201 ggtaaagctg ttgcgattgc tggtaagaaa aaataatata ggaggtaaaa gtcttggcta
    55261 aaccaacacg taaacgtcgt gtgaaaaaga atatcgaatc tggtattgct catattcacg
    55321 ctacatttaa taacactatt gttatgatta ctgatgtgca tggtaatgca attgcttggt
    55381 catcagctgg tgctcttggt ttcaaaggtt ctcgtaaatc tacaccattc gctgctcaaa
    55441 tggcttctga agctgctgct aaatctgcac aagaacacgg tcttaaatca gttgaagtta
    55501 ctgtaaaagg tccaggttct ggtcgtgagt cagctattcg tgcgcttgct gccgctggtc
    55561 ttgaagtaac agcaattcgt gatgtgactc cagtgccaca caatggtgct cgtcctccaa
    55621 aacgtcgccg tgtataatca tcgcattaca ctgcttttcg tttaagaggg agtaactaaa
    55681 tgatcgagtt tgaaaaacca aatataacaa aaattgatga aaataaagat tatggcaagt
    55741 ttgtaatcga accacttgaa cgtggctacg gtacaactct tggtaactct cttcgtcgtg
    55801 tacttctagc ttctctacca ggagcagctg tgacatctat caacattgat ggtgtgttac
    55861 atgagtttga cacagttcca ggtgttcgtg aagacgtgat gcaaatcatt ctgaacatta
    55921 aaggaattgc agtgaaatcg tacgttgaag acgaaaaaat catcgaactg gatgttgaag
    55981 gtcctgctga agtaacagct ggtgacattt tgacagatag cgatattgaa attgtaaatc
    56041 cagatcatta tctctttaca atcggtgaag gttcttctct aaaagcgact atgactgtta
    56101 acagtggtcg tggatatgta cctgctgatg aaaataaaaa ggataatgca ccagttggaa
    56161 cacttgctgt agattctatt tatacaccag ttacaaaagt caactatcaa gtggaacctg
    56221 ctcgtgtagg tagcaatgat ggtttcgaca aattaaccct tgaaatcttg acaaatggaa
    56281 caattattcc agaagatgct ttagggcttt cagcacgtat tttgacagaa catcttgatt
    56341 tgtttacaaa tcttactgag attgctaagt caactgaagt gatgaaagaa gctgatactg
    56401 aatctgacga ccgtatttta gatcgtacga ttgaggaact ggacttgtct gtgcgttcat
    56461 acaactgttt aaaacgtgcc ggtatcaata ctgtgcatga tttgacagaa aaatctgaag
    56521 cagagatgat gaaagtacga aatcttggac gcaagagttt ggaagaagtg aaactcaaac
    56581 tcattgattt gggtcttgga ttaaaagata aataaaggag gaatacatgg cttaccgtaa
    56641 actaggacgc actagctcac aacgtaaagc aatgcttcgc gatttgacaa ctgacctttt
    56701 gatcaacgaa tcaatcgtga caactgaagc tcgtgctaaa gaaatccgta aaactgttga
    56761 aaaaatgatt actctaggta aacgtggtga tttgcatgca cgtcgtcaag cagctgcttt
    56821 cgtacgtaat gaaatcgcat ctgaaaacta tgatgaagca actgataagt acacttctac
    56881 tacagcactt caaaaattgt tctcagaaat cgcacctcgt tatgctgaac gtaacggtgg
    56941 atacactcgt atccttaaaa ctgaaccacg tcgtggtgat gcagcgccaa tggcgatcat
    57001 cgaattagta taaaatcatc aattttgttg agtgttatga tgatggagtc ttgtgctctt
    57061 agtctagctc tggtctaccg ctaggatttc ggtcctagcg ggaacactca tcataagttg
    57121 ggatagtaga cgcttgttta cgaaattgtt tttttcttaa gaacaacttc gtaagcaggc
    57181 gtttttgagt attttcgtta gaattatgct atactatttg aaaagaatcc tgtttaatgt
    57241 taaggtttct tattttaaga agaattggag tttacttatg aaagcgatta taactgttgt
    57301 tggtaaagat aaatctggaa ttgttgcagg tgtttctggt aaaattgcag aattaggatt
    57361 gaatattgac gatatctctc aaactgtatt ggatgaatat tttacgatga tggctgttgt
    57421 atctagtgat gaaaagcaag attttaccta tcttcgtaat gaatttgaag cttttgggca
    57481 aactttgaat gtaaaaatca atattcagag tgcagcgatt ttcgaagcta tgtataatat
    57541 ctaggaggtc atcatggata ttagacaagt tactgaaacc atcgccatga ttgaggagca
    57601 aaacttcgat attagaacca ttaccatggg gatttctctt ttggactgta tcgatccaaa
    57661 tatcaatcgt gctgcggaga aaatctatca aaaaattacg acaaaggcgg ctaatttagt
    57721 agctgttggt gatgaaattg cggctgagtt gggaattcct atcgttaata agcgtgtatc
    57781 ggtgacacct atttctctga ttggggcagc gacagatgcg acggactacg tggttctggc
    57841 aaaagcgctt gataaggctg cgaaagagat tggtgtggac tttattggtg gtttttctgc
    57901 cttagtacaa aaaggttatc aaaagggaga tgagattctc atcaattcca ttcctcgcgc
    57961 tttggctgag acggataagg tctgctcgtc agtcaatatc ggctcaacca agtctggtat
    58021 taatatgacg gctgtggcag atatgggacg aattatcaag gaaacagcaa atctttcaga
    58081 tatgggagtg gccaagttgg ttgtattcgc taatgctgtt gaggacaatc catttatggc
    58141 gggtgccttt catggtgttg gggaagcaga tgttatcatc aatgtcggag tttctggtcc
    58201 tggtgttgtg aaacgtgctt tggaaaaagt tcgtggacag agctttgatg tagtagccga
    58261 aacagttaag aaaactgcct ttaaaatcac tcgtatcggt caattggttg gtcaaatggc
    58321 cagtgagaga ctgggtgtgg agtttggtat tgtggacttg agtttggcac caacccctgc
    58381 ggttggagac tctgtggcac gtgtccttga ggaaatgggg ctagaaacag ttggcacgca
    58441 tggaacgacg gctgccttgg ccctcttgaa cgaccaagtt aaaaagggtg gagtgatggc
    58501 ctgcaaccaa gtcggtggtt tatctggtgc ctttatccct gtttctgagg atgaaggaat
    58561 gattgctgca gtgcaaaatg gctctcttaa tttagaaaaa ctagaagcta tgacggctat
    58621 ctgttctgtt ggattggata tgattgccat cccagaagat acgcctgctg aaaccattgc
    58681 ggctatgatt gcggatgaag cagcaatcgg tgttatcaac atgaaaacaa cagctgttcg
    58741 tatcattccc aaaggaagag aaggcgatat gattgagttt ggtggtctat taggaactgc
    58801 acccgttatg aaggttaatg gggcttcatc tgtcgacttc atctctcgcg gtggacaaat
    58861 cccagcacca attcatagtt ttaaaaatta agaaaatagg agaaatttta agttctattt
    58921 aagattagat gtgtatacta taatcattaa ataaagacct cctaatatta tttgaaacag
    58981 ataacactga attagtttga atttgatttt catctaatat ctttatttaa tgaactccta
    59041 aactttttca taataatctc cttcaaaagt cgcctgtatg ggtggctttt attttatcat
    59101 tcatgatata atagaagcaa acggaggacg gaaaatggta aaagtacgat tgtatttggt
    59161 acgtcatggc aagaccatgt ttaacacgat tggtcgcgcg caaggttgga gcgatactcc
    59221 cttaactgct gaaggtgaac gagggattca agagttagga attggtttgc gagaatctga
    59281 tctacagttt gagcgcgctt attcgagtga ttctggtcgt accattcaga ccatgggaat
    59341 tatccttgaa gagcttggct tgcaggggaa aatcccttat cgcatggaca agcgtatcag
    59401 agaatggtgt ttcggtagtt ttgatggagc ctatgatggc gatcttttca tgggcattat
    59461 tcctcgtatc tttaatgtgg accacgttca ccaattgtct tatgctgaac tggctgaggg
    59521 cttggtagag gtcgatacag ctggttgggc tgaaggctgg gaaaaactca gtggccgaat
    59581 taaggaaggc tttgaaatga ttgcaaaaga aatggaagat caaggtggag gtaacgccct
    59641 tgttgtcagc catggaatga ctattggaac cattgtttat ctgattaatg gcatgcatcc
    59701 gcatggtcta gataatggta gcgtgacgat tcttgaatat gaggacggtc agtttagggt
    59761 tgaagttgtc ggtgaccgta gttaccgaga gctaggacgt gagaagatgg aagaaggctc
    59821 tatttaatca gtctagactt gcttgccatg agctagggat ttgataagaa tatcaagata
    59881 agaaaaaaca gccgagggta ctcctttcgg ctgtttttga tgtggaaaac taaagtgtaa
    59941 tgctattgct tttagagatt ttcataaaca agagcaagga acctactgtt agaacagtca
    60001 ggatagttga caaggctgcg gctacaccgt aatttcctct gagaacctct gtataaatag
    60061 ctacagtcat tgttcttgtt ttgacattgt agaggaggat agaggataga agtagagagt
    60121 tctgaaatca gtgtgaccca agataggatg gctccagaaa taatacccga tagcatcatt
    60181 ggagttgtaa tcttagcaaa ggtattgaga cgactacttc ctaagctttc agcagcttct
    60241 tcaatacttg gtgctatttg ttgtaagcta gcaacagatg agcgaatagt ataaggtaat
    60301 cttctgacag atagagacat aatcaagatg aaagcagtcc ctgtaatcat aagaaatcca
    60361 cttccaaata gaccagtatt gaaggaagaa atgaaggcaa tccctagaac ggttcctgat
    60421 acaatataag gtaccatact gaggctgtca attaagtttg taaacaaatt ccgttttcta
    60481 acggctaggt aggagataaa tgtcgcaaat agaacaacta gaactaaggc aatcaaaggg
    60541 atacgaatgg tattgaaaat agcagatccc atacgattga aagctacctt gtaactgttt
    60601 ggagaataac ctttaacaaa taccatacct gatgttttta ggaaagaggt ataaattaag
    60661 tagatttgag gtaaaacaga gataaagata attccgtaga ctgttgcata aatggcagcc
    60721 atttttcctt ttgtagtttt tttaggctca attggatgga gcggattcat gctgaaactg
    60781 tagcggtttg caatgtgttt ttggataagg aaaattgcca aggcaatgat aatcgccata
    60841 attgcaaaag cagaatttcc tccaacctcg ctaataaatt gggtataaat caggacaggg
    60901 aaagtccgat atccttcgcc aatcaacata ggcgttccaa agtctgagaa tgctctcata
    60961 aatacaagca aggagctgct agtaaggttg gaactagaag aggtaaaaca accgttacga
    61021 taggtttaaa tccgaaggac cccatgcttt cagctgcttc aagtagagaa ttgtcaatac
    61081 tgttcattgt tccagcaaca tatagaaata ccagtgggaa tagttgcagt gtaaagacaa
    61141 gtacaattcc tttgaatcca taaatatcga tagctggaag atgaagggca tttgtcaaaa
    61201 atttagtgat gcccccattt cgtcccagca agagaaccca ggagtaggct cctacgaaag
    61261 gagctgacat ggaagcaatg ataatcaata tttgtagaaa tttcttcccc ttgaagtcat
    61321 acatagagaa gagataagct aatagggttc ctacaactaa ggaagtgaca gtagcggtaa
    61381 tggaaaccct gaaactgttg actagtgtct cagagtagta ggctttacta aagaaagtga
    61441 caaaattaga tagtgagaat tgtccttcat gtataagtgc ttgcttgagc acggtaacga
    61501 taggataaac gagaaagaca agataggtaa gaaagatgaa gaaagaggag gctgtccaaa
    61561 tatttagttt tttacattcc atggttgact ccttttatca ggttttggga accatctaca
    61621 gaaaagatgt ttaatttttg cgtattgatt cgtagacgaa tacgattgcc tttttgtagt
    61681 tcttcttcaa aagttgattc ttcactaact taaatttttg aggcaaaacc tgtctcaatg
    61741 aaatactccg tatttagtcc aagatagacg ctatcgctaa tagttccttc gatatctcca
    61801 gattcatctt tgataaactc ttcgggacga atgcttacat gaatagcttg ctcctcaacc
    61861 tgatcaagag ctggcattcg aagggcatag ccatctgaaa agacgatata agcgccgtcg
    61921 ctccgttttt caagattggc agggataata tttgtgcgtc cgataaaggt tgccacaaac
    61981 tcattagctg gtttatgata gagttatttt ggtcggccga tttgttggat caccccatct
    62041 ttcataacag caatttggtc tgaaatagcc atggcttctt cttggtcgtg ggttacataa
    62101 acagttgtaa ttcccacttc gtgttggatt tctcggatgg cttgacgcat atccaagcga
    62161 agtttggcct ccagattact aagtggctcg ttcatgagga gaacacttgg attaaccgct
    62221 aaggcgcatg ccaaggtgac acgttgttgt tgtccaccac tgagtttatc gggctttcga
    62281 tccgcatatt gagcaatttg catgagttca agatacttgt tggtctgttg aatcaattct
    62341 tcttttggaa ccttcttttg cataagacca aaagcaacgt tgtctcggac agtcaaatgt
    62401 gggaaaatag cgtagttttg gaaaaccatc ccgatattgc gtttgctggg ttccatatta
    62461 ttgatttttg tatcatcgaa gtaaaattct ccaccttcga tactgttgaa acctgcaatc
    62521 atacgaagaa gggtcgtttt cccacatcct gaaggtccaa gaagggtaaa gagacttcct
    62581 tttggaattg taatgttcaa attctcaata acagggacat cgtggtagat ttttttggcg
    62641 ttaataattt tgatctcact catagtgaac ctcttttact gtttagattg gatatctgta
    62701 aagacttcgt tgtatttctt aacgatatct gatttattct tgatgacata atcataatct
    62761 tcagtgagtg ttttgatttt gtcaattggt ttcatgtttt cgcttgtttt agcattttta
    62821 cgaacaggac ggttagtagt ggttgtacca agtgtatctt gtacttcttg agagataata
    62881 aaatcgataa atttcttggc attttccata tttttagatt ttttaacgat agcagcacta
    62941 gcaggtagga agacggttcc ttcttttgga tagactacct taatgttagc tccgtcattt
    63001 aagagtttaa ctgctggatc ttcataagag agaccaacag tcatttctcc atcagcgact
    63061 gctttataga caccagatga acttaaaccg attttatagt atattgaaac tagaatagta
    63121 cacatctact tctaaaacat tgttagaaat cgatttgact gtcctgatta atttgtcttg
    63181 ttcttatttc attttactat accatcaata agtgtgaaaa gatcttttac ataagaccaa
    63241 gccttatcat ctttgtaacc accttgagct tgtagcatat ttgttaattg agcaaaggcg
    63301 ctagaagagt ttgctgggtc agcagttgcg atttttcctt ttagttcagg tttgagaagg
    63361 tcgctatatc cttcgatgtt catgccttta gttaaatcag ggtggacgat taaaacacta
    63421 ccatctagtg tataaggagt agagaagcca gttgtgtttt gatattcttt gataacatta
    63481 tcattttctt ttgaaatata gttttcaaag agttctccgt gggtagcata ttgtgtataa
    63541 gaaccaccaa agataacatc agctacagga acttcttttt ctgactctag ttttttgaaa
    63601 agttctccag taccagcttg aatcagttct attttgatac catatttttc ttcaaaggca
    63661 ggaatagttg ctccaattaa gccttctgag tttggtgaat aaacgactag cgaaccaccg
    63721 tctcctttat cagatgaact gtcatcggca gattcattag aagaacaagc agcataatac
    63781 atccatttct ttttcatgat ggatacctcc gttgtgttat ttaagtttat tttaaaacaa
    63841 tataagcgtt tttaaaacct acaattctat cctatagtgt attgaatcta taacagtaca
    63901 ctttgactgc taaaatattt ctataaatta atttgacttt cctgatagag atgttcacat
    63961 cttatttcaa ttcactatat tagagtaaaa ttctctacaa aaagaagaat agcctatttg
    64021 actattcttc cgagtgattt caatttcttt ggggaaatat ggagatactt tttaaatact
    64081 ttggcaaaat atttatagtc tgaaaatcca acttggtcag agatagcgct taaaggggag
    64141 ttgggagatt cagccatctt atctatagct tgtttcaggc gatattgtaa gatatattca
    64201 tttagagtca tggggaagtc ttctttgata accttatata gatgcttgtt atctgcaaat
    64261 agctagagca tttcaaggaa atgaactaga aataacaatt aatatggtgg ttcagaaata
    64321 ccttttgata atcaataaga tcttcaggat gaagtgcgtt gactccatcc atttcatatt
    64381 tccgatttaa taaacgatat ttgttttcac caaattgatg aaaagggagt agttgaactt
    64441 ggtcgatatt taatgagtta aatagagtag cgaatttttc tgcatcctct aaactattgt
    64501 taaaattagg aataactggg attcttaaaa cgatagtttt attttgagaa aaagcataat
    64561 gaatgttttt aataatcatt tgattaaaaa ccccagtcac ttttttatgt tttatagaat
    64621 tataatgttt taggtctgtg tagataaaat ccacatattg aattaaatca ataaattttt
    64681 catgatcaac aaaggcagta gtttcaatgg cagtgtgtat gtgatgttct ttagctgatt
    64741 ttaagatggc tttagcaaat tcaaactgag caaatatttc acctcctgat aaagttaaac
    64801 ctccaccgga ttcttcgtaa aattctttgt cttttaatac ctctgtaata atttcttcta
    64861 cagtcttttc ttcaccgact aaggtgaatt tctctcgttg agcatctttc attttttcag
    64921 gtttcattct ttgagattca ggattagaac accatggaca gcgcagagga catcctttta
    64981 aaaaaacagt tgtacgaata cccgggccgt catgaattga aaagtgttga atattaaaaa
    65041 taattccttt agatatttcc ataagagttc ctcctcttca taagtctatc ctatcacaaa
    65101 aacgaaagaa aaacaattac gaacgaaagt ttaatttgtt gttttttgct ttttattttg
    65161 gtagaataaa acggaggtgt aaaatgaaaa gattggaaca aattattaaa ttagtatcag
    65221 aatatgaaaa gatcgacgtt aatacattat cggaaaaatt aaatgtatcg aaagtaacga
    65281 ttagaaaaga tttagataaa ttagagtcaa aaggtttatt acacagagag catggatatg
    65341 ctgtattaaa tagtggagat gacttaaatg tacgtttgtc aattaattat gaaattaaga
    65401 gaaaaattgt tcaggaagca gtaaaattgg tgtcagataa tgaaacaata atgatagaat
    65461 ctggatcgac ctgtgcttta cttgctgagg aaatttgcaa gcaaaaaaga aatgttacga
    65521 ttgtaacaaa ttcatttttt atagcaaatt ttgtgagagc ttatgattca tgtcgtatta
    65581 ttgttcttgg tggagagttt cagaaggatt cacaggttac tgtgggacct ttattaaaag
    65641 aaatgataca gacttttcat gtgcgtcaag cttttgttgg gacagatggc tacgataaag
    65701 agatgggctt tacaggaaaa gatttaatgc gcagtgaggt agttcaatat atttcagcag
    65761 cgtcggataa agtcattgta ctaactgact caagtaaatt tgataaaagg ggtacagtaa
    65821 gaagatttgc tttaagtcaa gtctatgaag taataacaga cgaaaaactt tctaaacaaa
    65881 atatagctac attagaaaat gctgggataa tggttaaggt agtttcgtaa gaggttaagt
    65941 gtatgaatca agataggaat aaactgcttt ctaaaattgc ttatctgtat tatattgaaa
    66001 acttaaatca gtcacaaata gcagcaaaat taggaattta tagaacctct attagtagaa
    66061 tgttaacaga agcaaggaat gcaggaattg ttaaaattga aatagagaat tttgatacaa
    66121 atatgtttaa gttggaaaat tatgtaaaag aaaaatatgg tctggaaagt ttagaaatta
    66181 ttccaaatga atttgatgat aatccaacaa ttttatctga aagaatttct caagttgcag
    66241 caggtgtcct taggaattta attgatgata atatgaaaat tggcttttct tgggggaaaa
    66301 gtttaagtaa tttagtagat ttaattcaca gtaaaagtgt ccgaaatgtt cacttctatc
    66361 ctctagcagg tggtcctagt cacatacacg ctaaatacca tgtgaataca ctgatttatg
    66421 aaatgtctag aaaatttcat ggagagtgta catttatgaa tgcaacgatt gtgcaagaaa
    66481 ataaattgtt agcagatggt attttgcaat caagatattt tgaaaatttg aaaaatagtt
    66541 ggaaagattt agatatagct gtagtcggaa ttggtgattt tagcaataaa ggaaaacatc
    66601 aatggttaga catgcttaca gaggatgact ttaaagaatt gaccaaagtt aaaactgtag
    66661 gagaaatttg ttgtcgattt tttgattcaa aaggtaaaga agtctatgaa aacttacagg
    66721 aaagaacgat agcaatctct ttggaagatt taaaaaatat tcctcaaagt ttagctgttg
    66781 cttacggtga tacgaaagta tcttcgattc tttctgtctt gcgtgctaat ttagtaaatc
    66841 atttgattac agacaaaaat acaattttaa aagttttgga agaagatggg gatttgactt
    66901 ttagagagat tctaggtgag tgaaaatgat agactgatca gtttatcgtt ttttcttttt
    66961 agtcgattgc acatttgtgc tcatataaac aaaaatagtt tatctgttgt ttttggattg
    67021 acaactttat tatgtagttg tattctatag ttacaaaaga aaattttaaa atttcaaatg
    67081 aaaaaagctt tttacatagt gaaatgagga ggaatttatg gaaattattg ttccagatca
    67141 aattatcatg ggtttaattt tatatgctgg tgatgcgaaa caacatattt ataaagcgtt
    67201 agattacata aaaaatggta catgtgaacg gtgtgaagaa gaaatccagt tagctgatgc
    67261 cgccttatta gaagcccata atctacaaac aaaattcttg gcacaagaag cgtctggtac
    67321 aaagacagaa attacagctc tctttgttca ttcacaagat catctcatga ctagtatgac
    67381 ggagattaat ttaatcaaag aaattattag tttgagaaaa gaacttcata aaaaataata
    67441 ctagagtatt atcattgtta ttaacataga ggaggaaaac ataatggtga agattggttt
    67501 gttttgtgca gcaggttttt ctactggtat gcttgtaaat aatatgaaaa ttgcagcgca
    67561 agctagtgga gttgaggcag aaatagaggc gttttctcag tctaaattag cggattatgc
    67621 gccaaatata gatgttgcac tattgggtcc acaagttgct tatacattag ataaatcaaa
    67681 agaaatttgt gataagtgtg atgttccgat agctgttatt ccgatgatgg actatggtat
    67741 gttagatgga aaaaaagtat tagatttggc cctatctttg attagtgggt aagaaaagga
    67801 gatttattat ggcaaagatg gatgttcaga aaatcattgc accgatgatg aagtttgtga
    67861 atatgcgtgg cattatagct ctaaaagatg ggatgttagc aattttgcca ttgacagtag
    67921 ttggtagttt attcttgatt atgggacaat tgccgttcga aggattaaat aagagcattg
    67981 ctagtgtttt tggagctaat tggacagagc cgtttatgca agtatattca ggaacttttg
    68041 ctattatggg tctaatttct tgtttttcaa ttgcctattc ttatgctaag aatagcggag
    68101 tagaggcttt accagctgga gttctatctg tatctgcatt ctttattttg ctaagatcat
    68161 cttatatccc taaacaaggt gaggcaattg gggatgctat tagtaaagtt tggtttggag
    68221 gtcaaggaat tatcggtgct atcattatag gtttggtagt aggaagtatt tataccttct
    68281 ttataaagag aaaaattgtt attaagatgc cagaacaagt tccacaagct attgccaaac
    68341 agtttgaagc aatgattcca gcatttgtaa ttttcttact ttctatgatt gtatatattt
    68401 tagcgaagtc attgactaat ggcggaacat tcatagaaat gatttattct gctattcaag
    68461 ttccattgca aggtttaact ggatcttggt atggtgcaat tggaattgca ttctttatat
    68521 catttttgtg gtggtttggt gttcatggac aatcggtagt aaatggagta gtgacagctc
    68581 tgcttttatc taatcttgat gctaataaag ctatgttagc ctctggtaat ctatcattag
    68641 aaaatggtgc acatattgtt actcaacaat ttttagattc atttttaatt ctatcaggtt
    68701 cagggattac gtttggtctt gtagttgcca tgctttttgc agcaaaatca aaacaatacc
    68761 aagccttagg aaaagttgcc gcttttccag caatatttaa cgtaaatgag ccagttgtat
    68821 ttggatttcc gattgtcatg aatccagtta tgtttgtacc tttcattctt gttcctgtac
    68881 ttgcagctgt gatagtatat ggagctattg caacaggttt catgcagcca ttctcagggg
    68941 taacattgcc ttggagtaca ccagctattt tatcaggatt tttggtgggt ggatggcaag
    69001 gagttattac tcagctggtg atattagcga tgtctacatt ggtttatttt ccattcttta
    69061 aagtacagga tcgtttagct taccaaaatg aaatcaaaca atcttagagg tatttgtgtg
    69121 ttactgttaa actcacacat ttgtgctaaa aattagagag ttaaaatttt tctagttaaa
    69181 agcttgaaaa tttctataaa aatcggtatt atattttcga aagaaataaa aatattttcg
    69241 aaagaaaggt ggttacgatg gtaaatacag aagtagcaag aacaacaatc aagacagaat
    69301 attttggcag ccttactgaa aggatgaaca aatatcgaga agatgtttta aataaaaaac
    69361 cttatattga tgctgagaga gcagttctag caacacgcgc ctatgaacga tacaaggaac
    69421 aacctaatgt cctaaaacgt gcatatatgc tgaaagaaat tttggaaaat atgactatct
    69481 atattgaaga agaatctatg attgggggaa atcaagcttc ttccaataaa gatgctccta
    69541 tttttccgga atatacgcta gaatttgttc tcaatgagtt ggatcttttt gaaaagcgtg
    69601 atggagatgt tttctatatt acagaagaaa caaaagaaca acttagaagt attgctccgt
    69661 tttgggaaaa taataattta cgtgctagag ctggtgcctt attacctgaa gaagtgtctg
    69721 tttatatgga aacaggattc ttcggtatgg aaggtaagat gaattctgga gatgctcacc
    69781 tagcagttaa ctatcagaaa cttttgcaat ttggcttaag aggttttgaa gagcgggctc
    69841 gtaaagcaaa agcagctcta gatttaacag atccagcaag tattgataaa tatcattttt
    69901 acgactctat atttatcgta atcgatgcta ttaaagtata tgcaaagcgc tttgttgctc
    69961 ttgctaaaag tttagccgaa aatgcaaatc ctaaacgtaa gaaagaatta cttgagattg
    70021 cagatatttg ctctagagtc ccatatgaac cggcaactac ttttgcagaa gctattcaat
    70081 cagtttggtt tattcaatgt attttacaaa ttgaatctaa tggccactct ctttcatatg
    70141 gccgttttga tcaatatatg tatccatata tgaaggctga tttagaaagt ggtaaagaaa
    70201 cagaagatag cattgttgaa cgtctgacaa atctttggat taagacaatt acaattaata
    70261 aggttcgcag tcaatcacat acattttctt cagcaggaag tcctttatat caaaatgtta
    70321 caattggtgg acagactcga gataagaagg atgctgttaa cccattatct tatttggtat
    70381 taaaatcagt tgcacaaacc catctaccgc aacctaatct aactgtacgt taccatgcag
    70441 gtttagatgc tcgtttcatg aatgagtgta ttgaagtgat gaaacttggt tttggtatgc
    70501 ctgcatttaa taatgatgag attattattc cttcttttat tgcaaaagga gtattggaag
    70561 atgatgctta tgattacagt gccattggat gtgttgaaac ggcagttcca gggaaatggg
    70621 gctatcgttg cacaggtatg agttatatga acttccctaa ggttctactt atcacgatga
    70681 atgatggaat tgatccggct tcgggtaaac ggtttgcacc aagctttggt cattttaagg
    70741 atatgaagaa cttttctgaa ttagaaaatg cttgggataa aacactaaga tatttgacac
    70801 gaatgagtgt tattgttgaa aattctattg atttatcatt ggaacgagaa gttcctgata
    70861 ttctatgttc agcattgact gatgattgta ttggtcgtgg aaaacacctt aaagaaggtg
    70921 gagcagtata tgattatata tcaggattgc aagttggaat tgcaaatttg tcggattcat
    70981 tagctgcaat taaaaaattg gtgtttgagg aagaacgtat aagcccaagt cagctttggc
    71041 atgcactgga aacagattat gccggagaag aaggtaaggt cattcaagaa atgttgattc
    71101 atgatgcacc taagtatggt aatgatgatg attatgctga caaattggtt actgctgctt
    71161 atgacattta tgttgatgaa attgctaaat atcctaatac acgttatgga agaggtccaa
    71221 ttggaggaat tcgttattca ggaacatctt ctatctcagc caacgtaggg cagggacgtg
    71281 gaacattagc aactccagat ggacgcaacg cgggtacacc gttagcagag ggttgttcac
    71341 catcacataa tatggatcaa cacggcccta catctgtttt aaaatctgtt tcaaaattac
    71401 caacagatga aatcgtaggt ggggttctct taaatcagaa agtaaatcct caaacgttag
    71461 ccaaagaaga agataaatta aaactaattg ctttgttacg aacattcttt aatcgtttac
    71521 atgggtacca tattcaatac aatgttgttt ccagagagac gctgattgac gctcagaaac
    71581 atcctgaaaa acacagagac ttaattgttc gtgttgcagg atactctgca ttcttcaatg
    71641 ttctttctaa ggcaacccaa gatgacatta taggacgtac tgagcatact ttgtaaaata
    71701 aagaggttct ttttatggaa tttatgcttg acacattaaa tttagatgag attaaaaagt
    71761 ggtctgaaat tttgccgcta gctggggtaa cttcaaatcc cactattgca aaaagagagg
    71821 gttctattaa tttttttgaa cgaatcaaag atgtaagaga attgattggc tctacaccct
    71881 ctattcatgt tcaggtgatt tctcaagatt ttgaaggcat cttaaaggat gctcataaaa
    71941 ttcgaagaca agcaggagat gatatattta tcaaagtacc tgttactcca gctggattac
    72001 gtgcaataaa ggcgctaaaa aaagagggct accatatcac tgcaacagct atttatacag
    72061 ttattcaggg attattagct atcgaagcag gagcggatta cctagctcca tattataata
    72121 gaatggaaaa tctgaacatt gattcaaatt ctgtcattcg tcaattagct cttgctattg
    72181 atagacagaa ctctcctagt aagattttag ctgcatcctt taaaaatgta gcacaagtaa
    72241 ataatgcttt agctgcaggt gcgcatgctg ttacagcagg agcggatgtt tttgaatcag
    72301 ctttcgccat gccatctatc caaaaggcgg ttgatgattt ttctgacgat tggtttgtta
    72361 ttcaaaatag tcgttccatt tagatagaga ggaaatacat atgagaattt ttgctagtcc
    72421 ttctagatat attcaggggg aaaatgcctt gtttgaaaat gccaaatcaa ttttggattt
    72481 gggaaattac cctattctat tatgcgatca gttggtttat gatattgttg gaaaacgatt
    72541 tgaagattac ctacataggt atggtttcca tattgttctg gcgctattta atggtgaagc
    72601 ttctgacaat gaaatcaatc gagttgttgc cttggctgag aaagaaaatt gtgatagtat
    72661 tatcggtctt ggtgggggaa agacgattga tagcgcaaaa gctattgcag atttgattga
    72721 aaagcctgtt attattgctc caacaattgc atcgaccgac gcacctgtat ctgctttatc
    72781 tgttatttat acagatgaag gtgcatttga tcattatcta ttttattcta aaaatccaga
    72841 tttagttttg gttgatacaa aagttatttc acaagcccct aagcgtttat tagcgtctgg
    72901 tattgcagat ggtttagcaa cttgggttga ggcgcgtgcg gttatgcagg caaatggaaa
    72961 aactatgttg ggacaacagc aaacattggc tggagttgca attgcgaaga aatgtgaaga
    73021 aacgctgttt gcagatggtt tacaggctat ggcagcttgt gaagctaaag tggtgacacc
    73081 agcattagaa aatattgttg aagctaatac tttattgagt ggtctaggtt ttgaaagtgg
    73141 aggattagct gcggcgcatg caattcataa tggttttact gcattgacag gtgacattca
    73201 tcatttaaca catggtgaaa aagtagctta tggaacttta gtacaactat tattggaaaa
    73261 tagacctaaa gaagaacttg ataagtatat tgagttttac aaaaaaattg gtatgccaac
    73321 aactctaaaa gaaatgcatt tggatcaagt tggatatgat gatttaataa aagttggtaa
    73381 acaagcaact atggagggtg agacaattca tcagatgccg tttaagattt cgccttcaga
    73441 tgttgctcaa gctattatcg ctgtagatgc ctatgtaaat tcaaaataaa caataaggac
    73501 tactgttttc caaatggtag tcttttattg atccctgtat tgaattctat agcagattga
    73561 aataggatga gaacaaatcg attgggaaag taaaattaat ttctataaat gttttagcaa
    73621 ttgtttcgta ctatttcaga ttcagtccac tatacgttct tcataaatca aaaagcgaca
    73681 taggttgtcg gctatttatt gtgaatacat taattagcat tccagtttta tcttcggtct
    73741 aaaataagta ttttgtgcta tacgagataa gcttcttgac ttactccttg atttactgca
    73801 taacaatggg ataaaaagtg ggagatagag caattcatag tcatcaaaat taatgagata
    73861 cagtatacag ttttttcttt aaacacattt caaattccct caaaaatggt ataatagtaa
    73921 catcacaaaa ttggagagag accatgagtt tttacaatca taaagaaatt gaacctaagt
    73981 ggcagggcta ctgggcagaa catcatacat ttaagacagg aacagatgca tcaaaaccta
    74041 agttttatgc gcttgatatg ttcccttatc cgtctggagc tggtctgcat gtaggacacc
    74101 cagaaggtta tactgcaacc gatatcctca gtcgttacaa acgtgcgcaa ggctacaatg
    74161 tccttcaccc aatgggttgg gatgcttttg gtttacctgc agagcaatac gctatggata
    74221 ctggtaatga cccagcagaa tttacatcgg aaaacattgc caacttcaaa cgtcaaatca
    74281 atgcgcttgg attttcttat gactgggatc gtgaagtcaa cacaacagat ccaaactact
    74341 acaagtggac tcaatggatt ttcaccaagc tttacgaaaa aggcttggcc tatgaagctg
    74401 aagtgccagt aaactgggtt gaggaattgg gaactgccat tgccaatgaa gaagtgcttc
    74461 ctgacggaac ttctgaacgt ggaggctatc cagttgtccg caaaccaatg cgccaatgga
    74521 tgctcaaaat cacggcttac gcagagcgct tgctcaatga cttagatgaa ctagattggt
    74581 cagagtctat caaggatatg caacgcaact ggattggtaa atcaactggt gccaatgtaa
    74641 ctttcaaagt aaaaggaaca gacaaggaat ttacagtctt tactactcgt ccggacacac
    74701 ttttcggtgc gactttcact gttttggctc ctgaacatga attagtagat gccatcacaa
    74761 gcacagagca agcagaagca gtagcagact acaaacacca agccagcctt aagtcagact
    74821 tggctcgtac cgaccttgcc aaagaaaaaa ctggtgtatg gactggtgct tatgccatca
    74881 atcctgtcaa tggtaaggaa attccaatct ggattgcgga ttacgttctt gctagctatg
    74941 gtacaggtgc ggtaatggct gtgcctgccc acgatcaacg tgactgggaa tttgccaaac
    75001 aatttgacct tccaatcgtc gaagtacttg aaggtggaaa tgttgaagaa gctgcctaca
    75061 cagaagatgg ccttcacgtt aattcagact tcctagatgg actcaacaaa gaagacgcta
    75121 ttgccaagat tgtggcttgg ttggaagaaa aaggctgtgg acaagagaag gtaacctacc
    75181 gtctccgcga ctggctcttt agccgtcaac gttactgggg tgagccaatc ccaatcattc
    75241 attgggaaga tggaacttca acagctgtcc ctgaaagtga attgccactt gtcttgcctg
    75301 taaccaagga tatccgtccc tcaggtactg gtgaaagtcc actagctaac ttgacagact
    75361 ggcttgaagt gactcgtgaa gatggtgtca aaggtcgtcg tgaaacaaat actatgccac
    75421 aatgggcagg ttcaagctgg tactacctcc gctatattga cccacacaat actgagaaat
    75481 tggctgacga ggatctgctc aaacaatggt tgccagtaga tatctacgtg ggtggtgcgg
    75541 aacatgctgt acttcacttg ctttacgctc gtttctggca taaattcctc tatgacctcg
    75601 gtgttgttcc aactaaggaa ccattccaaa aactctttaa ccaaggaatg attttgggaa
    75661 caagctatcg tgaccaccgt ggggctcttg tggcgactga caaggttgaa aaacgtgatg
    75721 gttctttctt ccatgtggaa acaggggaag agttggagca agcgccagcc aagatgtcta
    75781 aatcgctcaa gaacgttgtt aacccagacg atgtggtgga acaatacggt gccgacactc
    75841 ttcgtgttta tgaaatgttt atgggaccac ttgatgcttc gattgcttgg tcagaagaag
    75901 gtctagaagg aagccgtaaa ttccttgacc gtgtttaccg tttgattaca agcaaggaaa
    75961 ttgttgcgga aaacaatggc gctctcgaca aagtttacaa cgaaaccgtt aaagctgtca
    76021 cagaacaaat tgagtccctc aaattcaaca cagccattgc tcaacttatg gtctttgtca
    76081 acgctgccaa caaggaagac aaactttatg tagactacgc caaaggcttc gttcagttga
    76141 ttgctccatt tgctcctcac ttggcagaag agctctggca aacagttgca gcaacaggag
    76201 aatctatctc ttatgtagct tggccaactt gggatgaaag caaattagtt gaagacgaaa
    76261 tcgaaatcgt cgtccaaatc aaaggtaaag tccgtgccaa actcatggtt gctaaagacc
    76321 tgtcacgcga agaattgcaa gaaattgctc tcgctgatga aaaagtcaag gtagaaattg
    76381 acggtaagga aatcgtgaaa gtgattgcgg tacctaacaa actcgttaat atcgtcgtta
    76441 aataacgagt ttattagctc tatctgccac cttcaatagt ccactggact attgaagcca
    76501 actaaattgg ttaatattgt tgtgaaataa gataggaatc cttcagagta gaatctgggg
    76561 gattttttga atcttcttat gaaagtatgt tatactatgg tcaactataa aatttgaaaa
    76621 gcgaaacaag gggaaagtta tgccagtaaa tgaatatggt cagatgattg gtgagtcaat
    76681 ggaaggttat acacctggtg cactgccttc tattgatttc ttagaagggc gttatgctcg
    76741 aatagaagct ctttcagtgg aaaagcatgc ggaggattta ttagctgttt atggccctga
    76801 tacgcctcgg gaaatgtgga cctacctctt tcaggaatca gtggcagata tggaggagct
    76861 ggttagcctt ttaaatcaga tgttggctcg taaggaccgt ttttactatg caatcataga
    76921 caaggcaact ggtaaggctt tgggaacttt ttctctcatg cgtattgacc agaataatcg
    76981 agtaatagaa gtgggagctg tcactttttc tccaaaactc agggggacac ggatagggac
    77041 agaagcccag tatctactgg cgcgctatgt ctttgaagag cttaactatc gtcgctatga
    77101 gtggaaatgt gattctctta atctgccatc cagacgagca gcggaacgtt tgggatttgt
    77161 ctatgaagga accttccgtc aggcagtggt ttataagggg cgtacgaggg atacggattg
    77221 gttgtctatg attgataagg actggcctca agtcaaagct cgattggaag catggctgac
    77281 tcctgaaaat tttgataaaa ctgggcaaca atacaagagt ttgagagaac tttaagaggt
    77341 gttgagatga ttactattaa aaagcaagaa attgtcaagc tagaggatgt tttgcatctc
    77401 tatcaggctg tcggttggac aaattatacc catcaaccag agatgctgga gcaggcctta
    77461 tctcattcat tagtgattta tgtggcgctt gatggtgatg ctgtagtggg cttgattcgt
    77521 ttggttggag atggtttttc atcagttttt gtacaggatt tgattgtttt gcctaactat
    77581 cagcgccaag ggattggtag tctcttgatg aaagaggctt taaaagatta caaagatgcc
    77641 tatcaagtcc agctggtgac agaagagaca gaaaaaaacg taagatttta tcgttctatg
    77701 ggttttgaag ccttatccac ctatgattgt ataggaatga cttgggtgaa tcgagaaaaa
    77761 taacaaaact tgttttttct taagcaaagt ttaaggatgg tctagtatca tatagtcatt
    77821 aaataaagac ctcctaactt tatttaataa aatcctaaac ttttttcatc acaatctcct
    77881 aatgaagcca cccaatcagg tggctttttt gcgtggtgag gtgctggtga tagaaatttt
    77941 ttgcaaaata gtaaaatttt agaaaagtta agctagtttt aagtttcgtc ttgtatcatg
    78001 tagttattaa ataaagacct cctaacttta tttaataaaa tcctaaactt ttcattttca
    78061 taataatctc ccttaactcc acccaatcag gtggagtttt ttagctctat ttcaggattt
    78121 ttgggactat tctaaaaata atttttcgat atttttcggt atttttcgga ttttggtcgg
    78181 ggaattggcg gggacttttt gagattttgg aggggatttt tttagcgaat atgactaaga
    78241 aataggtctg tggtcgcttc agctagttca aactcaattt gattgtaagt gactgttaat
    78301 tgaaggactg gaactactgt aataatgatt ttgcttgtct agtagtggcg tattaaatga
    78361 aaagtgacat gtaagattgt ctcttcgttt acgaaatcaa aatttctatg aaattgatag
    78421 aatccctaac gttctcttaa ttttaaccgt cttgtcgtac agcggttgaa gaaaatgtaa
    78481 acctttgaca aaattcgtga actatgggat aataaaaagg aattgagtac tagttctata
    78541 tcataggcta gaaaagaccc caagctcacg accaaataag cttgaggtct tttttgacac
    78601 tatttgtcct tgtttagcca tttatcgact atacgaagaa cgacaccgac cacaattggt
    78661 ccgatgatag ttttgagtac taattccatc atgggctatc tcacctcctt tcgtaggcgg
    78721 tgtagaagtg ccgtataata ttataccaca taagtgctaa acttaggagt cacccaatca
    78781 ggtggctttt ttgtttgtgg cttggttttt tgatataata gagccatggg tagaatttta
    78841 gataatgaga taatggggga tgaggagtta gtagaacgca cgctccgtcc tcagtattta
    78901 cgtgaatata tcggacagga taaggtcaag gaccagctac aaatctttat tgaagctgca
    78961 aaaatgcggg atgaagcgct ggatcatgtg ctcttatttg ggcctccagg tctcgggaaa
    79021 acgaccatgg cctttgttat tgccaacgaa ctgggagtca atcttaagca gacgtcgggt
    79081 ccagtcattg aaaaagccgg agatctggta gctattttga atgagttaga gcctggggat
    79141 gtccttttta ttgatgagat ccatcgtttg ccaatgtcag tggaagaggt gctttatagt
    79201 gctatggagg acttctacat agatattatg attggggctg gtgaaggcag tcgcagtgtt
    79261 catttggagt tgcctccttt taccttgatt ggtgcgacga ctcgggctgg tatgctctca
    79321 aatccactac gggcacgttt tgggattaca ggtcatatgg agtattatgc ccatgctgac
    79381 ttgacagaaa ttgtcgagcg gacggcagat atttttgaga tggaaatcac tcatgaggca
    79441 gcatctgagt tggccctacg tagtcgtgga acccctcgta ttgccaatcg tctcctcaag
    79501 cgcgtgcgcg attttgccca gataatgggg aatggggtaa tcgatgatat tattaccgat
    79561 aaggctttga ctatgctgga tgttgaccat gaaggtttgg actatgtgga tcaaaaaatc
    79621 cttcgtacca tgattgagat gtacagtgga ggacctgttg gtctaggaac tctttctgtc
    79681 aatatcgccg aagagcgtga gacagttgaa gacatgtatg agccttactt gattcaaaaa
    79741 ggttttatca tgcggacacg gtctggacgg gtggcgactg ctaaggcata tgagcactta
    79801 ggttatgaat acagtgaaaa ataagcaaga aatcttagag gcttttagag aaaatccaga
    79861 tatgatggcc attctgacga tcatccgaga ccttggtttg aaagactcgt agttggcagc
    79921 aggttctgtc agaaatttca tctggaatct tttgtcagac aaatcccctt ttgatcatga
    79981 aacagatata gatgtgattt tctttgatcc agatttttct tatgaggaaa ccttattact
    80041 ggagaaaaag ctgagagagg attttcctca gtaccagtgg gaattgaaaa atcaggtcta
    80101 tatgcaccag cacagtcctc acactgcttt ctataccagt tctcgtgatg ctatgagtaa
    80161 gtatccagaa cggtgtacgg cagttggact gcgcttgaat gaagaatcag attttgaact
    80221 ttatgcacct tatggtttgg aggatatttt gaattttcaa gttcgtccaa ctcctcattt
    80281 cttagaaaat gaagaccgaa tggaactcta tcaaacacgt ttatccaaga aaaattggca
    80341 ggagaaatgg aaaaatttga tttttaaaaa tacttaagga aactttaagc tagggagtgt
    80401 acactaagtt cataagttaa gaagacctta acttaaactc ctaaaacttt ttcataataa
    80461 tctccctata aaaataaagt cgcccaatca ggcggcttat ttttttgaaa aatgggcatg
    80521 gtgcctgaga ataaatagct tagtgataga agaaaatggg gaaatatggt ataatgaaac
    80581 gatagatttt tgaataggaa taagatcatg tttggatttt ttaagaaaga taaggctgtg
    80641 gaagtagagg ttccgacaca ggttcctgct catatcggca tcatcatgga tggcaatggc
    80701 cgttgggcta aaaaacgtat gcaaccgcga gtttttggac ataaggcggg catggaagca
    80761 ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca aggttattac ggtctatgct
    80821 ttttctacgg aaaactggac ccgtccagat caggaagtca agtttatcat gaacttgcca
    80881 gtagagtttt atgataatta tgtcccggaa ctacatgcga ataatgttaa gattcaaatg
    80941 attggggaga cagaccgcct gcctaagcaa acctttgaag ctttaaccaa ggctgaggaa
    81001 ttgactaaga acaacacagg attgattctt aattttgctc ttaactatgg tggacgtgct
    81061 gagattacac aggcgcttaa gttgatttcc caggatgttt tagatgccaa aatcaatcca
    81121 ggtgacatca cagaggaatt gattggtaac tatctcttta cccagcattt gcctaaggac
    81181 ttacgagacc cagacttgat tatccgtact agtggagaat tacgtttgag caatttcctt
    81241 ccatggcagg gagcctatag tgagctttat tttacggaca ccttatggcc tgattttgac
    81301 gaagcggcct tgcaggaagc tattcttgcc tataatcgtc gtcatcgccg atttggagga
    81361 gtttaggagg aaatatgacc caggatttac agaaaagaac cttgtttgca gggattgccc
    81421 tggctatttt cctaccaatt ttaatgattg ggggcctctt gcttcagata gcaatcggaa
    81481 tcatagccat gctagccatg catgaacttt tgaagatgag aggtctagag accatgacga
    81541 tggagggcct cttgaccctc tttgcaacct ttgcattgac cattcccttg gagaattacc
    81601 tgactttttt gccagttgat gggaatgtgg ttgcctatag tgttttgatt tcaatcatgt
    81661 taggaacgac cgtttttagc aagtcttata cgattgagga tgcggttttc cctcttgcta
    81721 tgagcttcta cgtgggcttt ggatttaatg ctttactaga tgctcgtgtt gcaggtttgg
    81781 acaaggctct cttagccttg tgtatcgtct gggcgacaga cagtggtgcc tatcttgttg
    81841 ggatgaacta tgggaaacga aagttagcac caagggtatc gcctaataaa acccttgagg
    81901 gtgccttggg tggtatttta ggagcaattt tagtaaccat tatctttatg atagttgaca
    81961 gtacagttgc tcttccatat ggaatttaca agatgtcagt ctttgctatt ttctttagca
    82021 ttgctggaca atttggtgat ttactagaaa gttcgatcaa acgtcatttt ggtgttaagg
    82081 attctgggaa atttatccct ggacatggtg gtgttttgga tcgtttcgat agtatgttgc
    82141 ttgtatttcc aatcatgcac ttatttggac tcttttaatc aaaagacgga ggaaacgcta
    82201 tgctcggaat tttaaccttt attctggttt tcgggattat tgtagtggtg cacgagttcg
    82261 ggcacttcta ctttgccaag aaatcaggga ttttagtacg tgaatttgcc atcggtatgg
    82321 gacctaaaat ttttgctcac attggcaagg atggaacggc ctataccatt cgaatcttgc
    82381 ctctgggtgg ctatgtccgc atggccggtt ggggtgatga tacaactgaa atcaagacag
    82441 gaacgcctgt tagtttgaca cttgctgatg atggtaaggt taaacgcatc aatctctcag
    82501 gtaaaaaatt ggatcaaaca gccctcccta tgcaggtgac ccagtttgat tttgaagaca
    82561 agctctttat caaaggattg gttctggaag aagaaaaaac atttgcagtg gatcacgatg
    82621 caacggttgt ggaagcagat ggtactgagg ttcggattgc acctttagat gttcaatatc
    82681 aaaatgcgac tatctggggc aaactgatta ccaattttgc aggtcctatg aacaatttta
    82741 tcttaggtgt cgttgttttt tgggttttaa tctttatgca gggtggtgtc agagatgttg
    82801 ataccaatca gttccatatc atgccccaag gtgccttggc caaggtagga gtaccagaaa
    82861 cggcacaaat taccaagatt ggctcacatg aggttagcaa ctgggaaagc ttgatccaag
    82921 ctgtggaaac agaaaccaaa gataagacgg caccgacttt ggatgtgact atttctgaaa
    82981 aggggagtga caaacaagtc actgttacac ccgaagatag tcaaggtcgt taccttctag
    83041 gtgttcaacc gggggttaag tcagattttc tatccatgtt tgtaggtggt tttacaactg
    83101 ctgctgactc agctctccga attctctcag ctctgaaaaa tctgattttc caaccggatt
    83161 tgaacaagtt gggtggacct gttgctatct ttaaggcaag tagtgatgct gctaaaaatg
    83221 gaattgaaaa tatcttgtac ttcttggcaa tgatttccat caatattggg atttttaatc
    83281 ttattccgat tccagccttg gatggtggta agattgtgct caatatccta gaagccatcc
    83341 gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac cttggccgga gtggtcatca
    83401 tggttgtctt gatgattgct gtgacttgga atgacattat gcgactcttt tttagataat
    83461 cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac gcttcgcgaa atgccaagcg
    83521 atgctcaagt tatcagccat gctcttatgt tgcgtgctgg ttatgttcgc caagtttcag
    83581 caggtgttta ttcttatcta ccacttgcca accgtgtgat tgaaaaagct aaaaacatca
    83641 tgcgccaaga attcgaaaag attggtgctg ttgagatgtt ggctcctgcc cttcttagtg
    83701 cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg tgaagacctt tacaaactaa
    83761 aaaaccgtga aaaatcagac tttatcttag gtccaactca cgaagaaacc tttacagcta
    83821 ttgtccgtga ttctgttaaa tcttacaagc aattgccact caacctttat caaattcagc
    83881 ccaagtatcg tgatgaaaaa cgcccgcgta atggacttct tcgtacacgt gagtttatca
    83941 tgaaggatgc ttatagtttc cacgctaact atgatagttt ggatagtgtt tatgatgagt
    84001 acaaagcagc ctatgagcgt attttcactc gtagtggttt agacttcaag gctattattg
    84061 gtgacggtgg agccatgggt ggtaaggata gccaagaatt tatggccatt acatctgctc
    84121 gtacagacct tgaccgctgg gttgtcttgg acaagtcagt tgcctcattt gacgaaattc
    84181 ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa atggatagtc tctggtgaag
    84241 ataccattgc ttactcaagt gagtctagct atgcagctaa cttagaaatg gcaacaaacg
    84301 agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt tactcgtgtt gcaacgccag
    84361 atgttaaatc aattgatgaa gttgcagcct tcctcaatgt tccagaagaa caaacgatta
    84421 aaaccctctt ctacattgca gatggcgagc ttgttgcagc ccttctagtt ggaagtgacc
    84481 aactcaacga agtcaagttg aaaaatcact tgggagcaga tttctttgac gttgctagcg
    84541 aagaagaagt ggcgaatgtt gttcaagcag gatttggttc acttggacca gttggtttgc
    84601 cagagaatat taaaattatt gcagatcgta aggtgcaaga tgttcgcaat gcagttgtcg
    84661 gtgctaacga agatggctac cacttgactg gtgtgaaccc aggccgtgat tttactgcag
    84721 aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc cccagatgga caaggtgtcc
    84781 ttaactttgc gcgtggtatt gagatcggtc atattttcaa actcggaact cgctattcag
    84841 caagcatggg agcagatgtc ttggatgaaa atggtcgtgc tgtgccaatc atcatgggat
    84901 gttacggtat cggtgtcagc cgtcttcttt cagcagtgat ggagcaacac gctcgcctct
    84961 ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg gggaatcaat ttccctaaag
    85021 aattggcacc gtttgatgtg catttgatta ctgttaatgt caaggatgaa gaagcgcaag
    85081 ccttgacaga aaaacttgaa gcaagcttga tgggagctgg ttatgaagtc ttgacagatg
    85141 accgtaacga acgtgtcggt gttaaattta gcgatagtga cttgattggt cttccaatcc
    85201 gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga agttaagatc aaggcaactg
    85261 gtgacaccat tgaggttcat gcagataacg tgcttgaaac gcttgaaatc ctaagcaaga
    85321 aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt aactagtttt taccttgttt
    85381 tttctgtata atgggagaaa tgagtagata aagaggtaaa tgtatgctaa gatttccaaa
    85441 ggattttgtc tggggatcct ctacttctgg accgcagaca gaaggacgtg tagctggtga
    85501 cggtaaggga gacaatctct gggattactg gttccaagtg gagccaaatc gttactataa
    85561 tgggattggt tcagataaga catcgacttt ttatgaaaat tgggagcggg atattgagct
    85621 tttgttagag actggtcaca cagcctttcg gacttctatt cagtggtcac ggatttttcc
    85681 acaaggctgt ggaaaagtca accctcaagg tgtggatttt tatcgtaagg tctttgaggc
    85741 tattaaggct aaaggacttc gtctgttagt caatctctat cattttgatt taccttttgc
    85801 ccttcaagag gatggtgatg gttgggaaaa taaggcgaca gtctcagcct atgaagacta
    85861 tgctcgtttt tgttttgaga cttatggaga tttagtggat caatggatta cctttaacga
    85921 gcccatcgtt cctgtagaat ttggttattt ttatgatgcc cattatccac ataaggtgga
    85981 tgcagaggca gctgttaagg tagcctatca tacacaattg gccagcagcc gggctgttaa
    86041 ggcttgccat gaacttttgc ctgattccaa gattgggatt gtcctcaact tgacaccggc
    86101 ttatccacgt agccagcatc ctgctgatgt caaggcagct cgtattgcgg ccctttttca
    86161 ggcccaatct ttcttagatc catctgtctt ggggacttat ccacaggagt tggtagaaat
    86221 cttgcatgaa cacggtcttt tacctgatgc tacagaggaa gagttggaac tcattcgtga
    86281 taatacggtg gacttccttg gtgtgaacta ctatcaacct ttgcgtgtta tggctcctcg
    86341 atttgctaag catccagata gtccactctt accagaacat ttttacgagc cttatgtgat
    86401 gcctggacgt aaaatcaatt ctcaccgtgg ttgggagatt tatgagcaag ggatttatga
    86461 catcgcccaa aatatcaagg aaaattatga caatattgaa tggatgttga ctgagaatgg
    86521 tatgggtgtt gaaggggaag aaaaattccg tcaagatgga atgattcaag atgattaccg
    86581 tattgacttt gtaaaaggtc atcttcgtga acttcaccgt gccattgaag atggtgccaa
    86641 ctgtaagggc tacttgattt ggacctttat tgactgctgg tcatggctca acagctataa
    86701 aaatcgctat ggtttggtcg aattagactt ggaaacgcaa gaacgtcgtc tgaagaaatc
    86761 aggccactgg ttcaaagaat taagcgataa taatggattt taaaaaggac tctgactgat
    86821 tatcccaatc ggtcagagtt ttttgcttac aggagcttaa tttgaactat accaattttt
    86881 actcttgaca agtgaaagaa acaagtatat aatgtttttg ctgattctat aaaagatgaa
    86941 ttagactata ccaattttaa ggagaaagca cagcttgcct gtgtcgtata tactatgtgt
    87001 ggaattgttg gtgttgttgg aaacacaaat gcaactgata ttttgattca agggcttgaa
    87061 aagcttgaat accgtggcta tgattctgcg ggaatttttg tcctagatgg tgctgataac
    87121 catttggtga aggctgttgg tcgtatcgca gaattgtctg ccaagacagc tggtgttgag
    87181 ggaacaactg gtatcggaca tactcgttgg gcaactcatg ggaaaccaac ggaagacaat
    87241 gctcacccac accgctctga gacagaacgt tttgtcttgg ttcacaatgg ggtgattgaa
    87301 aactaccttg aaattaaaga agaatacctt gctgggcacc acttcaaagg gcaaacagat
    87361 acggaaatcg ccgtacattt gattggaaaa tttgcggaag aagacggtct ctcagttctt
    87421 gaagccttta aaaaagctct tcatattatc cgtggttcat atgcctttgc cttgattgac
    87481 tctgaaaatc cagatgtcat ctatgtagcg aaaaacaaat ctccactttt gattggtctt
    87541 ggggaaggct acaatatggt ctgctcagat gctatggcta tgattcgtga aaccaaccaa
    87601 tacatggaaa ttcatgacca agagttggta atcgtcaagg ctgatagcgt ggaagttcaa
    87661 gactatgatg gtaacagtcg tgaacgtgct agctatactg cggaacttga cttgtcagat
    87721 atcggtaagg gaacttatcc ttactacatg cttaaggaaa ttgatgagca accaactgtt
    87781 atgcgtaaac tcattcaagc ctacacggat gatgctggtc aagtagtgat tgatcctgct
    87841 atcattaagg ctgttcaaga cgcagaccgc atctacatcc ttgcagctgg aacatcttac
    87901 catgcaggat ttgcttctaa gaaaatgttg gaagaattga cagatacacc agttgaactt
    87961 ggaatctcat ctgagtgggg ctacggtatg ccacttctca gcaagaaacc actcttcatc
    88021 tttatcagcc aatctggtga aacagcggat agtcgtcaag ttttggtcaa ggctaatgaa
    88081 atgggaattc caagcttaac agtgacaaac gttccaggtt caaccctctc acgtgaagcc
    88141 aactatacca tgctccttca cgcaggtcct gaaattgccg tggcatcaac taaagcctat
    88201 acagcgcaaa tcgcagccct tgccttcctt gcaaaagcag tcggagaagc aaatggtaat
    88261 gctaaagcgc aagcctttga cctggttcat gaattgtcaa tcgtagctca gtctatcgaa
    88321 tcaactcttt cagagaaaga aaccattgaa gccaaggttc gtgaacttct tgaaacaact
    88381 cgtaacgcct tttacatcgg acgtggtcaa gattactacg tagccatgga agcaagtctc
    88441 aaactcaaag agatttctta tatccagtgt gaaggttttg cggcaggaga actcaagcac
    88501 ggaaccattg ccttgattga agaaggaacg cctgtcttgt ctctcttgtc agatccagtt
    88561 cttgccaacc atactcgtgg aaatatccaa gaggtcgcag cccgtggtgc caaagtcctc
    88621 actatcgcag aagagaatgt agccaaagat accgacgata tcgtccttac gaccgtacat
    88681 ccatacctct caccaatttc aatggtcgta ccaacgcaat tagtcgctta ctttgcaacc
    88741 ctccaccgtg gcctcgatgt ggacaaacca cgtaaccttg ccaagtcagt aacggtagaa
    88801 taagctaaaa aagtctagtt atctaggcct ttttcttgtg agcaaattgg ttgcttgtac
    88861 ttaagattcg tgttagaata atttttcaaa ttgaaggaca gagatagaca aggagaatca
    88921 caatggtaga attgggaatt tcaacatttg gggaaataac ggagcttgaa gggactggac
    88981 aaacttacag tcatgctgaa cgcattcgcc agttggtggc agagattgag ctggctgaca
    89041 agattggttt ggacgtatat gggattggcg agcaccatcg ggcggatttt gcagtatcag
    89101 ccccagagat tgtcctggcc gctggggcag tcaataccaa gaaaatccgt ttgaccagtg
    89161 cagtcagcat tctgtcaagc atggatccga ttcgtttgtt ccaacagtat gccactatcg
    89221 atgctttgtc aaatggacga tcggagatta tggctggaag gggctctttc acggaatctt
    89281 tccctctgtt tggttatgac ttgaaagact acgactctct ttttgatgag aaattagact
    89341 tgcttcagtt agtcaatgaa aagaccaagt tagactggca aggtcgattg actcaaacga
    89401 ttgctggtaa agaagtttat cctcgtccag ttcaggacaa attgcccttg tggatagcta
    89461 caggtggtca tgtcgaatca acagtgaaga ttgctcaggc tggtctaccg attgtatatg
    89521 ctattattgg tggtaatcca cgttatttta aaaagttgat tcaggcttat cgtgagattg
    89581 gaagcgaagc gggccatgct gacaaagact tgaaagtggg agcccattct tgggggtgga
    89641 ttgcggaaga tggtgagcag gcggtgaaag attatttcca tccgactaag caagtagtgg
    89701 atgctatttc caaagaccgt ccgcactggc aggaattgcg ttatgagcaa tatttggagc
    89761 aggtagggcc aaatggcgcc atgtttgttg gcaatccaga tcaggtggcc gaaaaattga
    89821 ttcgcatgat agaggattta ggattggacc gcttcatgct tcatctaccg cttggttcta
    89881 tgcctcatga ccaggttctg agagctattg aactcttcgg aacacaagtt gcacccaaag
    89941 tacgagctta ttttgctatg aaagaggctt aataaaaaat cctaatcaag tttattagga
    90001 caacaaatat tgtacgaaaa tta
//
LOCUS       DBEJZV010000004        83185 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.04, whole genome shotgun sequence.
ACCESSION   DBEJZV010000004 DBEJZV010000000
VERSION     DBEJZV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 83185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83185
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.04"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            371..598
                     /locus_tag="ACL3S0_000320"
     CDS             371..598
                     /locus_tag="ACL3S0_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311298.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="ACL3S0_000321"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="ACL3S0_000321"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGR1311299.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSS
                     DTKEDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGNPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4798..5250
                     /locus_tag="ACL3S0_000322"
     CDS             4798..5250
                     /locus_tag="ACL3S0_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR1311300.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGDFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5269..6606
                     /locus_tag="ACL3S0_000323"
     CDS             5269..6606
                     /locus_tag="ACL3S0_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1311301.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6685..7569
                     /locus_tag="ACL3S0_000324"
     CDS             6685..7569
                     /locus_tag="ACL3S0_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1311302.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7569..8402
                     /locus_tag="ACL3S0_000325"
     CDS             7569..8402
                     /locus_tag="ACL3S0_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1311303.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8420..10513
                     /gene="nanB"
                     /locus_tag="ACL3S0_000326"
     CDS             8420..10513
                     /gene="nanB"
                     /locus_tag="ACL3S0_000326"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGR1311304.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFENATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10525..11628
                     /locus_tag="ACL3S0_000327"
     CDS             10525..11628
                     /locus_tag="ACL3S0_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR1311305.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11802..12500
                     /locus_tag="ACL3S0_000328"
     CDS             11802..12500
                     /locus_tag="ACL3S0_000328"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR1311306.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12519..14036
                     /locus_tag="ACL3S0_000329"
     CDS             12519..14036
                     /locus_tag="ACL3S0_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR1311307.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            14161..15489
                     /locus_tag="ACL3S0_000330"
     CDS             14161..15489
                     /locus_tag="ACL3S0_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1311308.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15741..16607
                     /locus_tag="ACL3S0_000331"
     CDS             15741..16607
                     /locus_tag="ACL3S0_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1311309.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16623..17462
                     /locus_tag="ACL3S0_000332"
     CDS             16623..17462
                     /locus_tag="ACL3S0_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1311310.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17735..18187
                     /locus_tag="ACL3S0_000333"
     CDS             17735..18187
                     /locus_tag="ACL3S0_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR1311311.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRRDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKEEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            18284..18628
                     /locus_tag="ACL3S0_000334"
     CDS             18284..18628
                     /locus_tag="ACL3S0_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311312.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            18638..18832
                     /locus_tag="ACL3S0_000335"
     CDS             18638..18832
                     /locus_tag="ACL3S0_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311313.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFNEHTWSTILIASLSGI
                     YIDYMSIDKSRKKSKRKKKK"
     gene            18915..19559
                     /locus_tag="ACL3S0_000336"
     CDS             18915..19559
                     /locus_tag="ACL3S0_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR1311314.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19728..20645
                     /locus_tag="ACL3S0_000337"
     CDS             19728..20645
                     /locus_tag="ACL3S0_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGR1311315.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            20663..21547
                     /locus_tag="ACL3S0_000338"
     CDS             20663..21547
                     /locus_tag="ACL3S0_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR1311316.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21563..22414)
                     /locus_tag="ACL3S0_000339"
     CDS             complement(21563..22414)
                     /locus_tag="ACL3S0_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR1311317.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22614..24671
                     /gene="pbp2b"
                     /locus_tag="ACL3S0_000340"
     CDS             22614..24671
                     /gene="pbp2b"
                     /locus_tag="ACL3S0_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGR1311318.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            24682..25278
                     /gene="recR"
                     /locus_tag="ACL3S0_000341"
     CDS             24682..25278
                     /gene="recR"
                     /locus_tag="ACL3S0_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGR1311319.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            25454..26497
                     /locus_tag="ACL3S0_000342"
     CDS             25454..26497
                     /locus_tag="ACL3S0_000342"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGR1311320.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            26581..27954
                     /gene="murF"
                     /locus_tag="ACL3S0_000343"
     CDS             26581..27954
                     /gene="murF"
                     /locus_tag="ACL3S0_000343"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGR1311321.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTVIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLFLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAVNGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENEAK"
     gene            27941..28552
                     /locus_tag="ACL3S0_000344"
     CDS             27941..28552
                     /locus_tag="ACL3S0_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGR1311322.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDVEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            28643..29347
                     /locus_tag="ACL3S0_000345"
     CDS             28643..29347
                     /locus_tag="ACL3S0_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGR1311323.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHVTILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATVSLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            29566..30939
                     /gene="ftsA"
                     /locus_tag="ACL3S0_000346"
     CDS             29566..30939
                     /gene="ftsA"
                     /locus_tag="ACL3S0_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGR1311324.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            30956..32215
                     /gene="ftsZ"
                     /locus_tag="ACL3S0_000347"
     CDS             30956..32215
                     /gene="ftsZ"
                     /locus_tag="ACL3S0_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGR1311325.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            32220..32891
                     /locus_tag="ACL3S0_000348"
     CDS             32220..32891
                     /locus_tag="ACL3S0_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGR1311326.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32901..33440
                     /locus_tag="ACL3S0_000349"
     CDS             32901..33440
                     /locus_tag="ACL3S0_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGR1311327.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            33440..33703
                     /locus_tag="ACL3S0_000350"
     CDS             33440..33703
                     /locus_tag="ACL3S0_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGR1311328.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33700..34485
                     /locus_tag="ACL3S0_000351"
     CDS             33700..34485
                     /locus_tag="ACL3S0_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGR1311329.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            34494..35282
                     /gene="divIVA"
                     /locus_tag="ACL3S0_000352"
     CDS             34494..35282
                     /gene="divIVA"
                     /locus_tag="ACL3S0_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGR1311330.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35630..38422
                     /gene="ileS"
                     /locus_tag="ACL3S0_000353"
     CDS             35630..38422
                     /gene="ileS"
                     /locus_tag="ACL3S0_000353"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGR1311331.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            38979..39341
                     /locus_tag="ACL3S0_000354"
     CDS             38979..39341
                     /locus_tag="ACL3S0_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311332.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNTLKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            39877..40569
                     /locus_tag="ACL3S0_000355"
     CDS             39877..40569
                     /locus_tag="ACL3S0_000355"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGR1311333.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            40622..43033
                     /locus_tag="ACL3S0_000356"
     CDS             40622..43033
                     /locus_tag="ACL3S0_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR1311334.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASNGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRYCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            43283..43984
                     /locus_tag="ACL3S0_000357"
     CDS             43283..43984
                     /locus_tag="ACL3S0_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311335.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            43986..46694
                     /locus_tag="ACL3S0_000358"
     CDS             43986..46694
                     /locus_tag="ACL3S0_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR1311336.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEN
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(46790..47281)
                     /gene="tpx"
                     /locus_tag="ACL3S0_000359"
     CDS             complement(46790..47281)
                     /gene="tpx"
                     /locus_tag="ACL3S0_000359"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGR1311337.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(47404..48333)
                     /gene="psaA"
                     /locus_tag="ACL3S0_000360"
     CDS             complement(47404..48333)
                     /gene="psaA"
                     /locus_tag="ACL3S0_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGR1311338.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(48365..49213)
                     /locus_tag="ACL3S0_000361"
     CDS             complement(48365..49213)
                     /locus_tag="ACL3S0_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGR1311339.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(49210..49932)
                     /locus_tag="ACL3S0_000362"
     CDS             complement(49210..49932)
                     /locus_tag="ACL3S0_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR1311340.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            50223..52115
                     /gene="pepO"
                     /locus_tag="ACL3S0_000363"
     CDS             50223..52115
                     /gene="pepO"
                     /locus_tag="ACL3S0_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGR1311341.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEERSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(52238..52867)
                     /locus_tag="ACL3S0_000364"
     CDS             complement(52238..52867)
                     /locus_tag="ACL3S0_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR1311342.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAYLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            53824..56046
                     /locus_tag="ACL3S0_000365"
     CDS             53824..56046
                     /locus_tag="ACL3S0_000365"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGR1311343.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            56076..56519
                     /gene="dtd"
                     /locus_tag="ACL3S0_000366"
     CDS             56076..56519
                     /gene="dtd"
                     /locus_tag="ACL3S0_000366"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGR1311344.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(57136..57786)
                     /locus_tag="ACL3S0_000367"
     CDS             complement(57136..57786)
                     /locus_tag="ACL3S0_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGR1311345.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            57898..58740
                     /locus_tag="ACL3S0_000368"
     CDS             57898..58740
                     /locus_tag="ACL3S0_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR1311346.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            58816..59253
                     /locus_tag="ACL3S0_000369"
     CDS             58816..59253
                     /locus_tag="ACL3S0_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGR1311347.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRN
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            59321..59572
                     /locus_tag="ACL3S0_000370"
     CDS             59321..59572
                     /locus_tag="ACL3S0_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311348.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLK"
     gene            complement(59714..60787)
                     /locus_tag="ACL3S0_000371"
     CDS             complement(59714..60787)
                     /locus_tag="ACL3S0_000371"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGR1311349.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLELAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            60943..61620
                     /locus_tag="ACL3S0_000372"
     CDS             60943..61620
                     /locus_tag="ACL3S0_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1311350.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            61613..62587
                     /locus_tag="ACL3S0_000373"
     CDS             61613..62587
                     /locus_tag="ACL3S0_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGR1311351.1"
                     /translation="MLDWKQFFLAYLRSRSRLFVYLLSLAFLVLLFQFLFASLGIYFL
                     YFFLLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(62636..64579)
                     /gene="thrS"
                     /locus_tag="ACL3S0_000374"
     CDS             complement(62636..64579)
                     /gene="thrS"
                     /locus_tag="ACL3S0_000374"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGR1311352.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(64637..64813)
                     /locus_tag="ACL3S0_000375"
     CDS             complement(64637..64813)
                     /locus_tag="ACL3S0_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGR1311353.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMKNF
                     LSDKEKQLNVRTRK"
     gene            complement(64820..64960)
                     /locus_tag="ACL3S0_000376"
     CDS             complement(64820..64960)
                     /locus_tag="ACL3S0_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGR1311354.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(65391..65591)
                     /locus_tag="ACL3S0_000377"
     CDS             complement(65391..65591)
                     /locus_tag="ACL3S0_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311355.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIISLLYSYRFRFSL"
     gene            65830..66459
                     /locus_tag="ACL3S0_000378"
     CDS             65830..66459
                     /locus_tag="ACL3S0_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR1311356.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            66600..66869
                     /gene="rpsO"
                     /locus_tag="ACL3S0_000379"
     CDS             66600..66869
                     /gene="rpsO"
                     /locus_tag="ACL3S0_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGR1311357.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            67683..68297
                     /locus_tag="ACL3S0_000380"
     CDS             67683..68297
                     /locus_tag="ACL3S0_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGR1311358.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(68589..69338)
                     /locus_tag="ACL3S0_000381"
     CDS             complement(68589..69338)
                     /locus_tag="ACL3S0_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGR1311359.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTNKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            69471..71807
                     /locus_tag="ACL3S0_000382"
     CDS             69471..71807
                     /locus_tag="ACL3S0_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR1311360.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFGVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFSRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            71909..72586
                     /locus_tag="ACL3S0_000383"
     CDS             71909..72586
                     /locus_tag="ACL3S0_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGR1311361.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGCLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQNHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            72573..73370
                     /locus_tag="ACL3S0_000384"
     CDS             72573..73370
                     /locus_tag="ACL3S0_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGR1311362.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            73387..74490
                     /locus_tag="ACL3S0_000385"
     CDS             73387..74490
                     /locus_tag="ACL3S0_000385"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR1311363.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            74746..75765
                     /gene="galE"
                     /locus_tag="ACL3S0_000386"
     CDS             74746..75765
                     /gene="galE"
                     /locus_tag="ACL3S0_000386"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR1311364.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            75767..76720
                     /locus_tag="ACL3S0_000387"
     CDS             75767..76720
                     /locus_tag="ACL3S0_000387"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR1311365.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(76782..76988)
                     /locus_tag="ACL3S0_000388"
     CDS             complement(76782..76988)
                     /locus_tag="ACL3S0_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGR1311366.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSRDVLEAVKNCPTRALIGNQEA"
     gene            77040..77516
                     /locus_tag="ACL3S0_000389"
     CDS             77040..77516
                     /locus_tag="ACL3S0_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGR1311367.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            77525..78196
                     /gene="cmk"
                     /locus_tag="ACL3S0_000390"
     CDS             77525..78196
                     /gene="cmk"
                     /locus_tag="ACL3S0_000390"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGR1311368.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            78327..78665
                     /locus_tag="ACL3S0_000391"
     CDS             78327..78665
                     /locus_tag="ACL3S0_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGR1311369.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDIVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            78668..79297
                     /locus_tag="ACL3S0_000392"
     CDS             78668..79297
                     /locus_tag="ACL3S0_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGR1311370.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            79537..80688
                     /locus_tag="ACL3S0_000393"
     CDS             79537..80688
                     /locus_tag="ACL3S0_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR1311371.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKKASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            81001..81750
                     /gene="truA"
                     /locus_tag="ACL3S0_000394"
     CDS             81001..81750
                     /gene="truA"
                     /locus_tag="ACL3S0_000394"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGR1311372.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            81740..82513
                     /locus_tag="ACL3S0_000395"
     CDS             81740..82513
                     /locus_tag="ACL3S0_000395"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR1311373.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            82491..82952
                     /locus_tag="ACL3S0_000396"
     CDS             82491..82952
                     /locus_tag="ACL3S0_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR1311374.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKFPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT        24877 a        15118 c        18617 g        24573 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtgtaaatag cataggctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgc cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgcatcag ctccacgctt ttacaatctc ttctctgtat ccagtgacac caaggaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgagat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa cccaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 agacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac atcatcctca gtaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtcaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcaag ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttatata
     4021 ttcaatatat tatgcggcta ttaaccttgt cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 atactaaaaa aaaaaagtat actctaattg aaaacggtaa caaaactaat ttagagaatg
     4261 aaatatagag tatttctctc ttaaaagttt ttggtgaaac gagatgtaga aaggagattt
     4321 agccaaagag tctattagtg ctagaataat agattagaat tattttagaa aaacgaagtg
     4381 agcagcttat aaattcaagt ccccaaatag attcatacta gtatcttttg caaaaaataa
     4441 agggcgactt ccttcatgaa tatcaatttc atctataagg aaggtagcta attgaactaa
     4501 cttatttatt ctgtttgtcg ctagaaaaat cagacctcct tgtgaagatt gaggagatac
     4561 ttaatgaaaa tcaaagaaga aactagcaag ctagtagcag attgcccaaa acaccgcttt
     4621 gaggttgtag ataagactga cgtatataat ccaaggtgaa gcgactgtgg tttgaagaga
     4681 ttttcaaaga gtatagacta gagagtagtg tttttatgtc cttctagtag aaaatgctag
     4741 acagaagaat ggggaacttg gataggaaaa atagattgag aaaggaggtt agaagagatg
     4801 attattacaa aaattagccg tttaggaact tatgtgggag taaatccaca ttttgcaaca
     4861 ttaatagatt ttctagaaaa aacaggacta gaaaatttaa cagaaggttc gattgctatc
     4921 gatggtaatc gattgtttgg gaattgcttt acttatctag cagatggtca agcaggggat
     4981 ttctttgaaa cacaccaaaa atatttggat attcatttag ttttggaaaa cgaagaagcc
     5041 atggctgtta catcgccgga aaatgtaagc gttacccaag aatatgatga agagaaagat
     5101 attgaattat acacagggaa agtggaacag ttggttcatt tgagagctgg tgaatgcctc
     5161 atcacttttc cagaagattt acatcaaccc aaggttcgta taaatgatga acctgtgaaa
     5221 aaagttgtct ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat gaaaaaaatg
     5281 agaaagtttt tatgtctagc tggaattgcg ctagcggctg ttgccttggt agcttgttca
     5341 ggaaaaaaag aagctacaac tagtactgaa ccaccaacag aattatctgg tgagattaca
     5401 atgtggcact cctttactca aggaccccgt ttagaaagta ttcaaaaatc agcagatgct
     5461 ttcatgcaaa agcatccaaa aacgaaaatc aagattgaaa cattttcttg gaatgacttc
     5521 tatactaaat ggactacagg tttagcaaat ggaaatgtgc cagatatcag tacagctctt
     5581 cctaaccaag taatggaaat ggtcaactca gacgctttgg ttccgctaaa tgattctatc
     5641 aagcgtattg gacaagataa atttaacgaa actgccttaa atgaagcaaa aatcggagat
     5701 gattactact ctgttcctct ttattcacat gcacaagtca tgtgggttag aacagatttg
     5761 ttaaaagaac ataatattga ggttcctaaa acttgggatc aactctatga agcttctaaa
     5821 aaattgaaag aagctggagt ttatggcttg tctgttccgt ttggaacaaa tgacttaatg
     5881 gcaacacgtt tcttgaactt ctacgtacgt agtggtggag gaagcctctt aacaaaagat
     5941 cttaaagcag acttgacaag ccaacttgct caagatggta ttaaatactg ggttaaattg
     6001 tataaagaaa tctcacctca agattctttg aactttaatg tccttcaaca agctaccttg
     6061 ttctatcaag gaaaaacagc atttgacttt aactctggct tccatatcgg aggaattaat
     6121 gccaacagtc ctcaattgat tgattcgatt gatgcttatc ctattccaaa aatcaaagag
     6181 tctgataaag atcaaggaat tgaaacctca aacattccaa tggttgtttg gaaaaattca
     6241 aaacatccag aagttgctaa agcattctta gaagcacttt ataatgaaga agactacgtt
     6301 aaattccttg attcaactcc agtaggtatg ttgccaacta ttaaggggat tagcgattct
     6361 gcagcctata aagaaaatga aactcgtaag aaatttaaac atgctgaaga agtaattact
     6421 gaagctgtta aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt acaagctggt
     6481 atgttaacta accaacacat tattgaacaa atgttccaag atatcattac aaatggaaca
     6541 gatcctatga aagcagcaaa agaagcagaa aaacaattaa atgatttatt tgaggctgtt
     6601 cagtagatgt aaaagactag aaaataggtg ggctagtgag ctgaaaagct ctagcccaat
     6661 cttgtaaaag aagggagaag gagaatggtt aaagaacgta atttaactcg ctggatattt
     6721 gttttgccag ctatgattat cgtaggatta ctctttgttt atccgttttt ctcgagtatt
     6781 ttttatagct ttaccaataa gcatttgatt atgcctaatt ataaatttgt tggtttggct
     6841 aactataaag ctgtgctatc agatcccaac ttctttaatg cgttctttaa ttcaattaag
     6901 tggaccattt tctcattagt tggtcaagtt ttagtagggt ttgtattggc tttagctctt
     6961 cacagagtac gccacttcaa gaaattatat aggaccttat tgattgttcc ttgggcattt
     7021 cctaccatcg tcattgcctt ttcttggcag tggattctaa acggggttta tggctactta
     7081 cctaatctaa tcgtaaaatt aggtttaatg gaacatacac ctgcattttt gacagatagt
     7141 acatgggcat tcctatgttt ggtgtttatc aacatttggt ttggagcacc aatgattatg
     7201 gttaatgtgc tttcagcttt gcaaacagta ccagaagaac aatttgaggc tgctaagata
     7261 gatggtgctt caagttggca ggtgttcaag tttatcgtct ttccacatat taaagtggtt
     7321 gtaggacttc tagttgtttt gagaactgta tggatcttta ataactttga cattatctac
     7381 ctcattactg gtggtggacc agccaatgct acaacgacgc ttccaatttt tgcttacaac
     7441 ctgggctggg gaactaaatt gttgggtcgt gcttcagcag ttacagtatt gctctttatc
     7501 ttcttggtgg cgatttgctt tatctacttt gctatcatca gtaagtggga aaaggagggt
     7561 agaaaataat gaagaagaaa tccagtattt atttagatat tctctcacat gtacttttag
     7621 ttggtgcgac catcgttgca attttcccat tggtatggat tatcatatct tctgtcaaag
     7681 ggaaagggga attaactcag tatccaacac gattttggcc tgaacagttt acattagatt
     7741 atttcactca tgttatcaac gatttgcact tcattgataa cattcgaaac agtttaatca
     7801 ttgccttggc tacaaccctc attgcgatta ttatttctgc tatggcagcc tatggtattg
     7861 ttcgattctt tcctaaattg ggagcaatca tgtcgagact actcgtcatt acctacattt
     7921 tcccaccaat tttgttagca attccctatt caattgccat tgctaaagtt gggttaacaa
     7981 atagtttatt tggcttgatg atggtttatc tatcttttag tgttccatat gcagtttggc
     8041 tcttagttgg atttttccaa acagttccaa ttggaattga agaagcggct agaattgatg
     8101 gtgcaaataa atttgttacg ttttataaag ttgtgctacc gattgtagca ccaggtattg
     8161 tagcaacagc tatttataca tttatcaatg cttggaatga attcctgtat gccttgattt
     8221 tgattaacaa tacaggaaag atgacagtag cagtagccct tcgttcactt aatggttcag
     8281 aaatactaga ctggggagat atgatggcag cgtctgttat tgtagttctt ccatcaatta
     8341 ttttcttctc tatcatccaa aataagattg caagtggatt atcagaagga tctgtgaagt
     8401 agacgaaaga aggaaaaaaa tgaataaaag aggtctttat tcaaaactag gaatttccgt
     8461 tgtaggcatt agtcttttaa tgggagtccc cactttgatt catgcgaatg aattaaacta
     8521 tggtcaactg tccatatctc ctatttttca aggaggctca tatcaactga acaataagag
     8581 tatagatatc agccctttgt tattagataa attgtctgga gagagtcaga cagtagtaat
     8641 gaaatttaaa gcagataaac caaactctct tcaagctttg tttggcctat ctaatagtaa
     8701 agcaggcttt aaaaataatt acttttcaat tttcatgaga gattctggtg agataggtgt
     8761 agaaataaga gacgcccaaa agggaataaa ttatttattt tctagaccag cttcattatg
     8821 gggaaagcat aaaggacagg cagttgaaaa tacactagta tttgtatctg attctaaaga
     8881 taaaacatac acaatgtatg ttaatggaat agaagtgttc tctgaaacag ttgatacatt
     8941 tttgccaatt tcaaatataa atggtataga taaggcaaca ctaggagctg ttaatcgtga
     9001 aggcaaggaa cattacctcg caaaaggaag tattgatgaa atcagtctat ttaacaaagc
     9061 aattagtgat caggaagttt caaatattcc cttgtcaaat ccatttcagt taattttcca
     9121 atcaggagat tctactcaag ctaactattt tagaataccg acactatata cattaagtag
     9181 tggaagagtt ctatcaagta ttgatgcacg ttatggtggg actcatgatt ctaaaagtaa
     9241 gattaatatt gccacttctt atagtgatga taatgggaaa acgtggagtg agccaatttt
     9301 tgctatgaag tttaatgact atgaggagca gttagtttac tggccacgag ataataaatt
     9361 aaagaatagt caaattagtg gaagtgcttc attcatagat tcatccattg ttgaagataa
     9421 aaaatctggg aaaacgatat tactagctga tgttatgcct gcgggtattg gaaataataa
     9481 tgcaaataaa gccgactcag gttttaaaga aataaatggc cattattatt taaaactaaa
     9541 gaagaatgga gataacgatt tccgttatac agttagagaa aatggtgtcg tttatgatga
     9601 aacaactaat aaacctacaa attatactat aaatgataag tatgaagttt tggagggagg
     9661 aaagtcttta acagtcgaac aatattcggt tgattttgat agtggctctt taagagaaag
     9721 gcataatgga aaacaggttc ctatgaatgt tttctacaaa gattcgttat ttaaagtgac
     9781 tcctactaat tatatagcaa tgacaactag tcagaataga ggagagagtt gggaacaatt
     9841 taagttgttg cctccgttct taggagaaaa acataatgga acttacttgt gtcccggaca
     9901 aggtttagca ttaaaatcaa gtaacagatt gatttttgca acatatacta gtggagaact
     9961 aacctatctc atttctgatg atagtggtca aacatggaag aaatcctcag cttcaattcc
    10021 gtttgaaaat gcaacagcag aagcacaaat ggttgaactg agagatggtg tgattagaac
    10081 attctttaga accactacag gtaagatagc ttatatgact agtagagatt ctggagaaac
    10141 atggtcggaa gtttcgtata ttgatggaat ccaacaaact tcatatggca cacaagtatc
    10201 tgcaattaaa tactctcaat taattgatgg aaaagaagca gtcattttga gtacaccaaa
    10261 ttctagaagt ggccgtaagg gaggtcaatt agttgtcggt ttagtcaata aagaagatga
    10321 tagtattgat tggaaatacc actatgatat tgatttgcct tcgtatggtt atgcctattc
    10381 tgcgattaca gaattgccaa atcatcacat aggtgtactg tttgaaaaat atgattcgtg
    10441 gtcgagaaat gaattgcatt taagcaatgt agttcagtat atagatttgg aaattaatga
    10501 tttaacaaaa taaaggagaa aaacatggtt aaatacggtg ttgttggagc agggtatttt
    10561 ggagctgaat tggctcgcta catgcaaaaa aatgatggag cagagattac tcttctctat
    10621 gatccagata atgcagaggc gattgcagaa gaattgggag caaaagtagc aagttcctta
    10681 gatgagttgg tttctagcga tgaagtagac tgtgttatcg tcgcaactcc aaataatctt
    10741 cataaggaac cggttattaa ggctgcacag catggtaaaa atgttttctg tgaaaaacca
    10801 attgcgcttt cttatcaaga ttgtcgcgag atggtagatg cgtgtaaaga aaacaatgta
    10861 acctttatgg caggacatat tatgaatttc tttaatggtg ttcatcatgc aaaagaactc
    10921 attaatcaag gagttatcgg agacgttcta tattgtcata cagctcgtaa tggttgggaa
    10981 gaacaacaac cgtcagtatc atggaaaaaa attcgtgaaa aatcaggtgg tcacttgtat
    11041 caccacatcc atgaattgga ttgcgttcaa ttccttatgg ggggcatgcc tgaaactgta
    11101 accatgacag gtggaaatgt ggcccatgaa ggtgaacatt tcggtgatga agatgatatg
    11161 atttttgtca atatggaatt ttctaataag cgttttgcct tgttagaatg gggttcagct
    11221 tatcgttggg gtgaacatta tgtcttaatc caaggaagca aaggtgccat ccgcttagac
    11281 ttattcaact gtaaaggaac tcttaagcta gatgggcaag aaagctattt cttgattcac
    11341 gaatcgcaag aagaagatga tgatcggact cgtatctatc atagtacaga gatggatgga
    11401 gcaattgctt atggtaaacc aggtaaacgt actccattat ggctatcatc tgtcattgat
    11461 aaagaaatgc gctatctgca tgagattatg gaaggagccc cagtatcaga agaatttgca
    11521 aaacttttga caggtgaagc tgccctagaa gcaattgcta ctgcagatgc ttgtacccag
    11581 tctatgtttg aagatcgcaa agtaaaattg tcagaaattg taaaataaat tttggtattc
    11641 tcctatttat aggtcgactt gctcctctga aagtactttt agaggagctg tttgactttg
    11701 ctagtttttg aaactgaaat ctattatact acaaactatt gaaagcgttt taattttaag
    11761 gtataataat ctcatagaaa taaagaaaag gaggaaagag gatgccacag attagcaaag
    11821 aagccttgat tgagcaaatc aaagatggaa tcatcgtttc ttgtcaggct cttcctcatg
    11881 aaccgcttta tacagaagcg ggaggggtga ttcccttgct ggtcaaagcg gctgagcaag
    11941 gtggagcagt cggtatccga gcaaacagtg ttcgcgatat caaggaaatt aaggaagtca
    12001 ctaaacttcc aatcattggg attatcaaac gtgattatcc acctcaggaa cccttcatca
    12061 cggctactat gaaagaagtt gatgaattgg cagaactgga catcgaggtg attgctctgg
    12121 attgtaccaa gcgtgaacgc tacgatggtt tggaaattca agagttcatt cgtcaggtta
    12181 aggagaaata tcctaatcag cttttgatgg ctgatactag tatcttcgaa gaagggctag
    12241 cagctgtaga agcaggaatt gactttgtcg gaacaacctt atcaggctac acatcctaca
    12301 gtccaaaagt agacggtcca gattttgaat tgattaagaa actctgtgat gccggtgtag
    12361 atgtcattgc agaaggaaaa attcatacac cagaacaagc caaacaaatc cttgaatatg
    12421 gagtgcgagg catcgttgtt ggtggcgcca ttactagacc aaaagagatt acagaacgct
    12481 tcgttgctag tcttaaataa gatgtgagag ggagttttat gtttaaagtt ttacaaaaag
    12541 ttggaaaagc ttttatgtta cctatagcta tacttcctgc agcaggtcta cttttgggga
    12601 ttggtggtgc actttcaaac ccaaccacga tagcaactta tccaatacta gacaatagta
    12661 tttttcaatc aatattccaa gtaatgagct ctgcaggaga ggttgtattc agtaatttgt
    12721 cactacttct ctgtgtggga ttatgtattg gcttagcgaa acgagataaa ggaaccgctg
    12781 cgttagcagg agtaactggt tacttagtta tgactgcaac gatcaaagct ttggtaaaac
    12841 tttttatggc agaaggatct gcaattgata ctggagttat tggagcatta gttgtcggaa
    12901 tagttgccgt atatttgcac aaccgatata acaatattca attaccttcc gctttaggat
    12961 tctttggagg ttcacgcttc gttcctattg ttacatcgtt ctcttctatc ttgattggct
    13021 ttgtcttctt tgttatttgg ccacctttcc aacaacttct tgtttctaca ggtggatata
    13081 tttctcaggc gggtccaatt ggaacttttc tatatggatt tttaatgaga ctttctggag
    13141 cagtaggctt acatcatata atttacccta tgttttggta tactgaactt ggtggtgttg
    13201 aaactgttgc aggacaaaca gtggttggag ctcaaaaaat attttttgct caattagccg
    13261 atccggccca ttctggatta tttacagaag gaacaaggtt ttttgcaggt cgtttctcaa
    13321 caatgatgtt cggtttaccg gctgcctgtt tagcgatgta ccatagtgtt cctaaaaatc
    13381 gtcgtaaaaa atacgcgggt ttgttttttg gagttgcttt aacatctttt attaccggta
    13441 ttacagaacc aattgaattt atgtttctat tcgtcagtcc ggttctatat gttgttcacg
    13501 cattccttga tggtgttagc ttctttattg cagacgtctt aaatatttca ataggaaaca
    13561 cattttcagg aggtgtaatc gatttcactt tatttggaat tttgcagggg aacgctaaga
    13621 cgaattgggt tcttcagatt ccaattggac ttatttggag tgttttgtat tatattattt
    13681 ttagatggtt cattactcaa ttcaacgttc taacgccagg acgaggagaa gaagtagatt
    13741 ctaaagaaat ttctgaatcc gcagattcaa cttcaaatac tgcagattat ttaaaacagg
    13801 atagcctaca aattatcaga gccttgggtg gatcaaataa tatagaagat gtagatgctt
    13861 gtgtgacacg tttacgtgta gctgtaaaag aagttaatca agttgataaa gcacttttaa
    13921 aacaaattgg tgcagttgat gtcttagaag tgaagggtgg cattcaagca atatatggag
    13981 caaaagcaat cttatataaa aatagtatta atgaaatttt aggtgtagat gattaagtac
    14041 ttactgactt aataaaaaac agaggagagt gatggatgag taggatgaaa tgaaatcgca
    14101 tacaagaaat aaagaactca ttatccaagt tggatacgct tattacatag gagaatacaa
    14161 atgaaattta gaaaattagc ttgtacagta cttgcgggtg ctgcggttct tggtcttgct
    14221 gcttgtggca attctggcgg aagtaaagat gctgccaaat caggtggtga cggtgccaaa
    14281 acagaaatca cttggtgggc attcccagta tttacccaag aaaaaactgg tgacggtgtt
    14341 ggaacttatg aaaaatcaat catcgaagcg tttgaaaaag caaacccaga tataaaagtg
    14401 aaattggaaa ccatcgactt caagtcaggt cctgaaaaaa tcacaacagc catcgaagca
    14461 ggaacagctc cagacgtact ctttgatgca ccaggacgta tcatccaata cggtaaaaac
    14521 ggtaaattgg ctgagttgaa cgacctcttc acagatgaat ttgttaaaga tgtcaacaat
    14581 gaaaacatcg tacaagcaag taaagctgga gacaaggctt atatgtatcc gattagttct
    14641 gccccattct acatggcaat gaacaagaaa atgttagaag atgctggagt agcaaacctt
    14701 gtaaaagaag gttggacaac tgatgatttt gaaaaagtat tgaaagcact taaagacaag
    14761 ggttacacac caggttcatt gttcagttct ggtcaagggg gagaccaagg aacacgtgcc
    14821 tttatctcta acctttatag cggttctgta acagatgaaa aagttagcaa atatacaact
    14881 gatgatccta aattcgtcaa aggtcttgaa aaagcaacta gctggattaa agacaatttg
    14941 atcaataatg gttcacaatt tgacggtggg gcagatatcc aaaactttgc caacggtcaa
    15001 acatcttaca caatcctttg ggcaccagct caaaatggta tccaagctaa acttttagaa
    15061 gcaagtaagg tagaagtggt agaagtacca ttcccatcag acgaaggtaa gccagctctt
    15121 gaataccttg taaacggatt tgcagtattc aacaataaag acgacaagaa agtcgctgca
    15181 tctaagaaat tcatccagtt tatcgcagat gacaaagagt ggggacctaa agacgtagtt
    15241 cgtacaggtg ctttcccagt ccgtacttca tttggaaaac tttatgaaga caaacgcatg
    15301 gaaacaatca gcggctggac tcaatactac tcaccatact acaacactat tgatggtttt
    15361 gctgaaatga gaacactttg gttcccaatg ttgcaatctg tatcaaatgg tgacgaaaaa
    15421 ccagcggatg ctttgaaagc cttcactgaa aaagcaaacg aaacaatcaa aaaagctatg
    15481 aaacaatagt ccttagttat tctataaaaa gtagtttttt aaagaaccta agagtgtata
    15541 cccccttttc cctctacaca gatagtgtaa gaaaaggggg cttttgttta aaatgtaaga
    15601 aactgtcacg aaattaaaat gaagttctta cataagcgaa tcataaaaaa tttcattttg
    15661 attttaaaac agttcaagaa agtcaaaaaa ttattctatt tgaaagagag gtgccgactg
    15721 tgaaagtcaa taaaatccgt atgcgggaaa cagtgatttc ctacgctttc ctagcaccag
    15781 tattattctt ctttgtcatc tttgtgttgg ctccgatggt gatgggcttc attacaagtt
    15841 tctttaacta ctcaatgact aaatttgagt ttgtaggctt ggataactat atccgtatgt
    15901 ttaaagatcc tgtctttaca aaatctctga ttaacacagt tattttggtt attggatctg
    15961 taccagttgt tgttctattc tcactctttg tagcatctca gacctatcat caaaatgtca
    16021 ttgccagatc cttctaccgt ttcgtcttct tccttcctgt tgtaacgggt agtgttgccg
    16081 tgacagttgt ttggaaatgg atttatgacc cgctatcagg gattctaaac tttgtcctta
    16141 agtcaagcca catcatcagc caaaacattt cttggttggg agataaaaac tgggcattga
    16201 tggcgattat gattattctc ttgaccactt cagttggtca gcccatcatc ctttatatcg
    16261 ctgccatggg gaatattgac aattcactgg ttgaagcggc gcgtgttgat ggtgcaactg
    16321 agtttcaagt tttttggaag attaaatggc caagccttct tccaacaact ctttatattg
    16381 caatcatcac aacaattaac tcattccagt gtttcgcctt gattcagctt ttgacatctg
    16441 gtggtccaaa ctactcaaca agtaccttga tgtactacct ttacgaaaaa gccttccaat
    16501 tgacagaata cggctatgcc aacacaattg gtgtcttctt ggcagtcatg attgctatcg
    16561 taagctttgt tcaatttaaa gtacttggaa acgacgtaga atactaaaga aaggagacag
    16621 ctatgcaatc tacagaaaaa aaaccattaa cagcctttac tgttatttca acaatcattt
    16681 tgctcttgtt gactgtgctg ttcatctttc cattctactg gattttgaca ggggcattca
    16741 aatcacaacc tgatacaatt gttattcctc ctcagtggtt ccctaaaatg ccaaccatgg
    16801 aaaacttcca acaactcatg gtgcagaacc ctgccttgca atggatgtgg aactcagtat
    16861 ttatctcatt ggtaaccatg ttcttagttt gtgcaacctc atctctagca ggttatgtat
    16921 tggctaaaaa acgtttctat ggtcaacgca ttctatttgc tatctttatc gctgctatgg
    16981 cgcttccaaa acaagttgtc cttgtaccat tggtacgtat cgtcaacttc atgggaatcc
    17041 acgatactct ctgggcagtt atcttgcctt tgattggatg gccattcggt gtcttcctca
    17101 tgaaacaatt tagtgaaaat attcctacag agttgcttga atcagctaaa atcgacggtt
    17161 gtggtgagat tcgtaccttc tggagtgtag ccttcccgat tgtgaaacca gggtttgcag
    17221 cccttgcaat ctttaccttc atcaatactt ggaatgacta cttcatgcaa ttggtaatgt
    17281 tgacttcacg taacaatttg accatctcac ttggggttgc gaccatgcag gctgaaatgg
    17341 caaccaacta tggtttgatt atggcaggag ctgcccttgc tgctgttcca atcgtcacag
    17401 tcttccttgt cttccaaaaa tccttcacac agggtattac tatgggagcg gtcaaaggat
    17461 aatactctgc gaaaatcgaa tgcaaactac gtcagcttca ccttgccata cttaagtatt
    17521 gcctgcggtt agcttcctag tttgttcttc aattttcatt gagtatagga aaatcaatct
    17581 atcaagatac agaagtatat tttatagatt tagagaatat agaagttata agtgtctaca
    17641 aaatggaggg tatgcagtta ctttatgaag ttttgtcaga cacttatcaa cttaagaatg
    17701 attttagtta attatcagaa acgaaggaaa gagtatgatt tttgacgatt tgaaaaacat
    17761 caccttttac aaagggattc atcccaattt agacaaggct atcgactatc tctaccaaca
    17821 tcgtagagat tcattcgaat taggaaagta tgagattgat ggagataaag tctttctagt
    17881 tgttcaggaa aatgtcctca atcaagttga gaataatcaa tttgaacacc ataagaacta
    17941 tgcagatttg catttgctga tagaagggca tgaatattcg agctacggtt cacgtatcaa
    18001 agaagaggca gtagcattcg acgaagcgag tgacattggc tttgttcatt gttatgaaca
    18061 ctacccactc ttattgggtt atcacaattt tgcgattttc ttcccaggtg agccacatca
    18121 gccaaatggt tatgcaggca tggaagaaaa ggttcgaaaa tatctcttta aaatcttgat
    18181 tgattaaaaa taggatgaat tgtttttttg taaagctttg ataatactct accatgaaat
    18241 tgatctttgt gaggtagaga aatgagaata aaatatttaa aaattggtat cttctaagta
    18301 tgctgcaaga gctagtttct tagatggaca ggggattaca gttgatgaga tgtcctggat
    18361 aattaggggc attgtgaatg gattgattgg tagatacata aaattaggta cttatgcagc
    18421 taagtatggt attagtatgg cgcgctcgat cttaagtagg gcagctgcaa ctgcggcagc
    18481 aagagtagga ttattgacta agatttttgg atggatttta cgaatagctg tgctcgcagc
    18541 tgatgtatat ggtaattttg ccaacaatat tgctgtagct tgggatgcac atgataaaat
    18601 ccctaacaat ggtcgtataa acttttaaaa tgcgagaatg aaagcacttt gtattttttt
    18661 attgaatatg ttagcttgga cagtgcttgc aatgataatt cgtggagggc tagatggatt
    18721 taatgagcat acttggagta ctattttaat tgcttcgctg tccgggatat atatagatta
    18781 tatgtccata gataaaagta gaaaaaagtc caaaagaaaa aagaaaaaat agatttgttc
    18841 atggtaggga cttatgaaag ttttactgac aaaaaagaaa acagtttaca aagaaaaatg
    18901 atggaggagc aaacatggca caaaaaggag taagccttat caaggcagca tttgatacag
    18961 ataactttct catgcgtttt agtgagaaag tcttggacat cgtgacagcc aatcttcttt
    19021 ttgtcgtctc ttgtttgccc atcgtgacga ttggagtggc taaaatcagc ctctacgaga
    19081 ccatgttcga agttaagaag agcagacggg tgcctgtttt taaaatctat ctaagatctt
    19141 tcaagcaaaa tctgaaacta ggtcttcagc tgggtttaat ggagttagga attgtgtttc
    19201 ttaccctttc agatctctat cttttctggg gtcaaacagc tctgcccttc caattgctga
    19261 aagccatttg tttaggtatt ctgatttttc ttactatcgt gatgctggct agttacccta
    19321 tcgcggcacg ttatgaccta tcttggaaag aaattcttca aaaaggattg atgttggcta
    19381 gttttaactt tccttggttc ttcctcatgt tagccattct tgtcctcatt gtgatggttc
    19441 tttatctgtc cgccttcagt ctactcttag gtggctcagt cttcctactt tttgggtttg
    19501 gactattggt ctttatccag actggattga tggagaaaat tttcgcaaaa taccaatagg
    19561 agctttattt ctgaaactac tttcaaaggc tccaaacgct attctataag cgagaaacta
    19621 aaatctaagt gtctataaga tattgaaagc cttttcggta aagtgtatac taaagaagta
    19681 aagaaaaatc tgctttagca gaaaataaaa ataataggag aaaatctatg tcagatttga
    19741 aaaaatacga aggtgtcatt ccagccttct acgcatgtta tgatgatcaa ggagaagtaa
    19801 gcccagaacg tacgcgtgcc ttggttcaat acttcattga taaaggtgtt caaggtcttt
    19861 atgtcaatgg ttcttctggt gaatgtatct accaaagcgt tgaagatcgc aagttgattt
    19921 tggaagaagt catggcggta gccaaaggta aattgaccat tattgcccat gttgcttgca
    19981 ataatactaa agatagtatg gaacttgctc gccatgctga aagcttggga gtagatgcta
    20041 ttgcaacgat tccaccaatt tatttccgct tgccagaata ctcagttgcc aaatactgga
    20101 acgatatcag ttctgcagct ccaaacacag actacgtgat ttacaacatt cctcaattgg
    20161 caggggttgc tttgactcca agcctttaca cagaaatgtt gaaaaatcct cgtgttatcg
    20221 gtgtgaagaa ctcttctatg ccagttcaag atatccaaac ctttgtcagc cttggtggag
    20281 aagaccatat cgtctttaat ggtcctgatg agcagttcct aggaggacgc ctcatggggg
    20341 ctagggctgg tatcggtggt acttatggtg ctatgccaga actcttcttg aaactcaatc
    20401 agttgattgc ggataaggac ctagaaacag cgcgtgaatt gcagtatgct atcaacgcaa
    20461 tcattggtaa actcacttct gctcatggaa atatgtacgg tgtcatcaaa gaagtcttga
    20521 aaatcaatga aggcttgaat attggatctg ttcgttcacc attgacacca gtgactgaag
    20581 aagatcgtcc agttgtagaa gcggctgctg ccttgattcg tgaaaccaag gagcgcttcc
    20641 tctaatctaa aaggaggtat ttatgacata ttacgttgca attgatatcg gtggaaccaa
    20701 catcaagtat ggtttggttg atcaagaggg gcaacttctt gaatcgcatg aaatgccaac
    20761 tgaggcgcat aagggtggac ctcatatctt acaaaagacc aaagatatcg tagctagtta
    20821 tttagaaaaa ggcccagtag caggtgttgc catatcttct gctgggatgg tggatccgga
    20881 taagggtgag attttctatg ctgggccgca aatccctaac tacgcaggca cccagttcaa
    20941 aaaggaaatc gaagaaagct ttactattcc ttgtgagatt gaaaatgatg tcaactgtgc
    21001 aggtcttgct gaggcagtat ctggttcagg caagggagca agtgtgacac tttgcttgac
    21061 cattggaacc ggtatcggtg gttgcttgat tatggatagg aaagtcttcc atggttttag
    21121 caattcagcc tgtgaagtcg ggtatatgca tatgcaggat ggagcttttc aagacttggc
    21181 ttctacaaca gctttagtga aatatgtagc tgaagcccat ggagaagatg ttgatcagtg
    21241 gaatggccgt agaattttca aagaagccac tgaaggaaac aaaatctgca tggaaggtat
    21301 tgaccgtatg gttgactatc taggaaaagg tctggcaaat atttgctacg ttgccaatcc
    21361 agaagtggtt attcttggtg gtggtatcat ggggcaagag gctatcctca aacctaagat
    21421 ccgtacagcc ttgaaagagg ctttggtacc aagtttagca gaaaaaacac gattagaatt
    21481 tgcccatcac caaaatacag cagggatgtt gggtgcatat tatcatttta agacaaaaca
    21541 atcctagttt ggctcagcca aactaggatt ttcttacacg tttttgtcta cgatagccgt
    21601 tgagtttttt attttcccag tagctattaa agattttttc cttgctttcg cgattgattt
    21661 ccaaaaagta ggcataaatc aaatcgataa agaagagcat aggaagttga gcggatattc
    21721 gttggatata ggagggttgg ctgtgggtgg ctacaagaac agtctctgta taggtctggc
    21781 tatctttatt gggaacactt gtaaagagta cagtctttgc ccccatctcc ttagcatcta
    21841 atagactatc taaaatagaa ggagttgagc ctgaaagtga gaagcccagt actagacaat
    21901 tttcatccat gatgctggtt gtccaggcaa agccgtcttg gtctgtcaaa gcttcgcaga
    21961 ccacacctag tcgcataaaa cgtaatttca tttcacgggc gacgaggcca gaactccctg
    22021 ttccaaagaa gtagatacgc tcagcatctt cgattagctg ggcaattcgt tctagttgga
    22081 tttcgtcaat caagtcttgt gtttgttccc tcatattgct ataacttctg aggactcgtt
    22141 tggtcagtgg actgtgcttg gagacttggt tggcttgatt ttctgcctga tgttggtatt
    22201 ggaaaataaa ttctcggtag ccagtaaagc cacacttttt agcaaagcgg gtcaaagcag
    22261 cttgagaaat atgtaatttt tgggtgactt gttgagaaga taaatcatct gtaatcgttt
    22321 cagcttgcaa aaaatagcga gcgatttctt gttctaggtc tgtcatttct tcaaaatgtg
    22381 aatcaatgat agttgcgata tctggtttgt ccatagggaa agctccttta catgagtcat
    22441 actggaagac tagatcagag aatagtcaca cttcattata acacataata taaggataga
    22501 taaataaaaa cgcatctctg ttttaaaaac gaaaaaatcg aaaaagcttc tctcttttcc
    22561 ataattttct actcaaattg tggtacaatt aagagtaaga ttttaagtta gaaatgagac
    22621 tgatttgtat gagaaaattt aacagccatt cgattccgat tcggcttaat ttattgtttt
    22681 caatcgtcat tttactcttt atgaccatta ttggtcgttt gttgtatatg caggttttga
    22741 acaaggattt ttacgaaaaa aagctagctt cagctagtca gaccaagatt acaagcagtt
    22801 cagcccgtgg ggaaatttat gatgctagtg gaaaaccttt ggtagaaaat acgttaaagc
    22861 aggttgtttc ctttacgcgt agcaataaaa tgacggctac agacttaaaa gaaacagcta
    22921 aaaagttact gacttatgtg agcatcagtt ctccaaattt gacagaacgc cagctggcgg
    22981 attactattt ggctgatcct gaaatctata aaaaaatagt ggaagctctc ccaagtgaga
    23041 aacgcttgga ttcagatggc aatcgtctat ccgaatcaga actgtataac aatgcggtcg
    23101 atagtgtaca aacgagtcaa ctaaactata cagaggatga aaagaaagaa atctatcttt
    23161 ttagtcagtt aaatgctgtt ggaaactttg cgacaggaac cattgcgaca gatcctctaa
    23221 atgattctca ggtggctgtt attgcctcta tttcaaagga gatgcctggc attagtattt
    23281 ctacttcttg ggatagaaag gttttggaaa cttccctttc ttctatagtt gggagtgtat
    23341 ccagtgaaaa agctggtctc ccagcggaag aagcagaagc ctatcttaaa aaaggctatt
    23401 ctctaaatga ccgtgtagga acctcctatt tggaaaagca atatgaagag accttacaag
    23461 gaaaacgctc ggtaaaagaa atccatctgg ataaatatgg caatatggaa agcgtggata
    23521 caattgagga aggtagtaag ggaaacaata tcaaactgac cattgatttg gccttccaag
    23581 atagcgtgga tgctttactg aaaagttatt tcaattctga gctagaaaat ggtggagcca
    23641 agtattctga aggtgtctat gcagtcgccc ttaacccaaa aacaggtgcg gttttgtcta
    23701 tgtcagggat taaacatgac ttgaaaacgg gagagttgac gcctgattcc ttgggaacgg
    23761 taaccaatgt ctttgttcca ggttcggttg tcaaggcggc gaccatcagc tcaggttggg
    23821 aaaatggagt cttgtcagga aaccagacct tgacagacca gtccattgtc ttccaaggtt
    23881 cagctcccat caattcttgg tatactcagg cttacggttc attccctatc acagcggtcc
    23941 aagctctgga gtattcatca aatacctata tggtccaaac agccttaggt cttatggggc
    24001 aaacctatca acccaatatg tttgtcggca ccagcaatct agagtctgct atggagaaac
    24061 tgcgttcaac ctttggcgaa tatggcttgg gtactgcgac aggaattgac ctaccagatg
    24121 aatctactgg atttgttccc aaagagtata gctttgctaa ttacattact aatgcctttg
    24181 ggcagtttga taactatacg ccgatgcagt tggctcagta tgtagcaact attgcaaata
    24241 atggtgttcg tgtggctcct cgtattgttg aaggcattta tggtaataat gataagggag
    24301 gactgggtga cttgattcag caactgcaac cgacagagat gaataaggtc aatatatccg
    24361 actccgatat gagcatcttg caccaaggtt tttatcaggt tgcccatggt actagtggat
    24421 tgacaactgg acgtgccttt tcaaatggtg ccttggtatc cattagcgga aaaacaggta
    24481 cagccgaaag ctatgtggca gatggtcagc aagcaaccaa taccaatgcg gtggcctatg
    24541 ccccatctga taatccccaa atcgctgtcg cagtggtctt tcctcataat accaatctaa
    24601 caaatggtgt aggaccttcc attgcgcgtg acattatcaa tctgtatcaa aaataccatc
    24661 caatgaacta gaaaggaaat tatgctttat ccaacaccta ttgccaagtt gattgacagt
    24721 tattctaagt taccaggtat cgggattaag acggctacgc gtctggcctt ttatacgatt
    24781 gggatgtctg ctgatgatgt caatgaattt gcaaaaaatc tcctttctgc taagagagaa
    24841 ttgacatatt gttctatttg tggacgtttg acagacgacg atccttgttc tatctgtact
    24901 gatccgactc gtgaccagac aacaatttta gttcttgagg atagtagaga tgtggcagcc
    24961 atggaaaata tccaagaata ccatggactc tatcatgtcc ttcatggcct catttctcct
    25021 atgaatggta tcagtccgga cgatatcaat ctcaagagcc ttatgactcg tcttatggat
    25081 agtgaggttt cagaagtgat tgtggcgact aatgctacag cggatggtga agcgacttcc
    25141 atgtatcttt cacgtttgct caagccggct ggtatcaagg ttacgcgtct agcacgaggt
    25201 ctcgctgtgg gagcggacat tgagtatgcg gacgaagtga cactcttacg agccattgaa
    25261 aatcggacag agttgtaagt gtaggcaaat ttacgaactc cattcattta taaaaaatca
    25321 aagaggctga aaatcgttcc tatcggcctc tttttgtata gtgtgatgag taggctcagg
    25381 ttcaagtttt aaaaaaccaa gcaaatatga tatactaaag agcgagtatt ctagtagaat
    25441 taggacaaat aatatgaaac aaacgattat tcttttatat ggtggacgga gtgcggaacg
    25501 cgaagtctct gtcctttcag ctgagagtgt catgcgtgcg gtcgattacg accgtttcac
    25561 agtcaagact ttctttatca gtcagtcagg tgactttatc aaaacacagg aatttagtca
    25621 tgctccgggg caagaagacc gtctcatgac caatgaaacc attgattggg ataagaaagt
    25681 tgcaccaagt gctatctacg aagaaggtgc agtggtcttt ccagtccttc acgggccaat
    25741 gggagaagat ggctctgttc aaggattctt ggaagttttg aaaatgcctt acgttggttg
    25801 caacattttg tcatcaagtc ttgccatgga taaaatcacg actaagcgtg ttctggaatc
    25861 tgctggtatt gcccaagttc cttatgtggc tatcgttgaa ggcgatgatg tgactgctaa
    25921 aatcgctgaa gtggaagaaa aattggctta tccagtcttc actaagccgt caaacatggg
    25981 gtctagtgtc ggtatttcta agtctgaaaa ccaagaagaa ctccgtcaag ccttaaaact
    26041 tgccttccga tatgacagcc gtgtcttggt tgagcaagga gtgaatgccc gtgaaattga
    26101 ggttggcctc ttgggtaact acgatgtcaa gagcacgcta cctggagaag ttgtcaagga
    26161 cgttgccttt tatgactacg atgccaagta tattgataac aagattacta tggatattcc
    26221 tgccaaaatc agtgatgatg tggtggctgt catgcgtcaa aatgcagaaa cagccttccg
    26281 tgccattggt ggccttggtc tatctcgttg cgatttcttc tatacagata agggagagat
    26341 ttttctcaac gagctcaata ccatgccagg ttttacccag tggtctatgt acccactact
    26401 ttgggacaat atggggatca gctacccaga actaatcgaa cgtttggttg accttgccaa
    26461 ggaaagcttt gacaagcgcg aagcgcattt gatataaaat gaaagagagg gtagaagcca
    26521 gaaccatcac tgcacggtga ctagagttct cggacttcag ccctttttaa aggagtagaa
    26581 atgaaattaa caatccatga aattgcccaa gttgttggag ccaaaaatga tatcagtatc
    26641 tttgaggaca cccagttaga aaaagctgag tttgatagtc gtttgattgg aactggagat
    26701 ttatttgtgc cacttaaagg tgcgcgtgat ggccatgact ttattgaaac agcctttgaa
    26761 aatggtgcag cagtaacctt gtctgagaaa gaggtctcaa atcatcctta cattttagta
    26821 gatgatgttt tgacagcctt tcaatcccta gcatcctact atcttgaaaa aacgactgtt
    26881 gatgtctttg ctgttacagg ttcaaatggc aagacaacga ctaaggatat gttggcgcat
    26941 ttactgtcaa caagatacaa gacctacaaa acacaaggca attacaataa tgagattggc
    27001 cttccttaca cagttctcca catgcctgaa ggaacagaaa agttggtctt ggagatgggg
    27061 caggaccact tgggagatat tcatctcttg tctgaattgg ctcgtccaaa aacagtcatc
    27121 gtgaccttgg ttggagaagc tcatttggcc tttttcaaag atcgttctga gattgctaaa
    27181 ggaaaaatgc aaattgcaga cggaatggct tcaggttcct tgtttttagc gccggctgac
    27241 cctatcgtag aggactattt gccaactgat aaaaaggtgg ttcgttttgg tcaaggagca
    27301 gagctggaaa ttactgactt ggttgagcgc aaagatagtc tgaccttcaa ggccaatttc
    27361 ttagagcaag tccttgattt gccagtaact ggcaagtaca atgcgacaaa tgctatgatt
    27421 gcatcctatg ttgccttgca agaaggagtt tcagaggagc aaattcgttt ggccttccaa
    27481 catcttgaat tgacgcgtaa ccgtaccgag tggaagaaag cagtcaatgg agcagatatc
    27541 ctgtcagatg tttacaatgc caatccaact gctatgaaac tgattttaga gactttctct
    27601 gccattccag ccaatgaagg tggcaagaaa attgcagttt tggcggatat gaaggagctt
    27661 ggtgaccagt ctgttcaact tcataatcag atgattttga gcctctcccc agatgtgctt
    27721 gatatcgtta ttttctatgg agaagatatt gctcagttgg ctcaattggc cagtcaaatg
    27781 tttccaatcg gccacgttta ctacttcaag aaaacagaag accaggatca atttgaagac
    27841 ctagtcaagc aggttaagga aagccttgga gcctatgacc aaatcttgct aaaaggttct
    27901 aactctatga atctagccaa attggtagaa agtttagaaa atgaagccaa gtgattttgt
    27961 taagtatctg caaagaatga ttgcccttac agatactggc ttaaccttta caaaagatcc
    28021 ttttgaccgt gagcgctacg aggacttgcg aagtctgtta tctgaaatgt tgaatcaggg
    28081 atcagacctg gatgtagaag aagtagcaga agtcttgaaa ccaacttcag cttatgcgac
    28141 tcccttaatg gacgtccgtg cttggattgt tgaggatgag aagatttgtc tggttagggg
    28201 acaaggagag gatagttggg ctttgccagg tggctttggt gaagtcggct attctccaac
    28261 tgaaaatatt ctcaaggaaa ttgaagaaga aaccggtttt aaagccaaag ttgaaagact
    28321 gctagctgtt tttgatacca atcgtttcca actacagagc aaacaatatg caaagtttgt
    28381 ttttgaatgt aagcttctcg atggacaatt ccaagaaaat caagaaatcg ctgaccttca
    28441 attttttgca attgaccaac tgccgaattt atctgaaaaa cgcattacca aggagcaaat
    28501 cgagattctt tggcaggttt atcaaggtca gagggagcaa tatcttgact aagaagatga
    28561 ttatcgtatt tctaaatcca tttttgacaa ctagcatggt ataataatat gcaggaaaat
    28621 tttgaattat gaggaagact agatgaattt atgggatatt ttctttacga ctcaggcaac
    28681 cgagccgccc aaatttgacc ttttttggta tgttagccta tttacgctct tagccttaac
    28741 cttttataca gcccatcgct atcgtgaaaa gaaggtttac caacgatttt tccaaatctt
    28801 gcagactgtt cagttaatcc ttctttatgg ttggtactgg gttaatcata tgccactgtc
    28861 agaaagccta cccttttacc attgccgtat ggctatgttt gtggtactct tgcttcctgg
    28921 tcagtccaaa tataaacaat actttgcatt attgggaaca tttgggacat tagcagcctt
    28981 tgtttatcca gtgccagatg cttacccttt tccacatgtc accattctat cctttatctt
    29041 tggtcattta gcactcttgg ggaactctct agtttatcta ttgagacagt ataatgcgcg
    29101 attgctggat gtgaagggaa tttttctcat gacctttgcc ctaaatgcct tgatttttgt
    29161 ggtcaatttg gtgacaggtg gcgattacgg atttttgaca aaaccgccat tggttgggga
    29221 tcacggtcta gtagctaatt atttacttgt ttcaattgtg ctggtagcta ctgtcagttt
    29281 gactaagaaa atcttagaat tctttttagc tcaagaagca gaaaaaatga ttgcaaagga
    29341 agcttaacac agagctttct tttttgctct tagagagttt ttacaagcag cttataaaat
    29401 aagaatttct gaatagacaa actcaaaaaa tggctgggaa atttaggaaa aaagcaagca
    29461 cgattaaatt ttttgtgtta taatattttg tgaatagcta tgcctatgtt tagctatgga
    29521 ataatacgaa gtgcgaaact tggaagatag agaggaagcg atgtaatggc tagagaaggc
    29581 ttttttacag gtctagatat tggaacaagc tctgtcaagg tgcttgtggc cgagcagaga
    29641 aatggtgaat taaatgtaat tggcgtgagt aatgccaaaa gtaaaggtgt aaaggatgga
    29701 attattgttg atattgatgc agcagcaact gctatcaagt cagccatttc ccaagcggaa
    29761 gaaaaggcag gcatttcgat taaatcagtg aatgtcggct tgcctggtaa tcttttgcag
    29821 gtagaaccaa ctcaggggat gattccagta acatctgata ctaaggaaat tacggatcaa
    29881 gatgttgaaa atgttgtcaa atcagctttg acaaagagta tgacacctga ccgtgaagtc
    29941 attaccttta ttcctgaaga atttattgtg gatggtttcc aagggattcg tgacccacgt
    30001 ggtatgatgg gggttcgcct tgaaatgcgt ggtttgcttt atacaggacc tcgtactatc
    30061 ttgcacaatt tgcgtaagac ggttgagcgt gcaggtgttc aggttgaaaa tgttatcatt
    30121 tcaccactag caatggttca gtctgttttg aacgaagggg aacgtgaatt tggtgctaca
    30181 gtgattgata tgggggcagg tcaaacgact gtcgctacaa tccgtaatca agaactccag
    30241 ttcacacata ttctccaaga aggtggagat tatgtaacta aagatatctc caaggttttg
    30301 aaaacctctc gcaaattagc ggaaggcttg aaactgaatt acggggaagc ctatccgcct
    30361 cttgcaagca aagaaacctt ccaagtagag gttattggag aagtggaagc agtcgaagtg
    30421 acggaagcct acttgtcaga aattatttct gcacgaatca agcacatcct tgaacaaatc
    30481 aagcaagaat tagatagaag gcgtctattg gacctccctg gtggtattgt cttaatcggt
    30541 gggaatgcca ttttaccagg tatggttgag cttgctcagg aagtctttgg cgtccgtgtc
    30601 aagctttatg ttccaaatca agttggtatc cgtaatccag cctttgcgca tgtgattagt
    30661 ttatcagaat ttgcgggtca attaacagaa gttaatcttt tggctcaggg agcgataaaa
    30721 ggtgagaatg acttaagtca tcagccaatt agttttggtg ggatgctgca aaaaacagct
    30781 cagtttgtac aatcaacgcc tgttcaacca gcacctgctc cagaagtaga gccggtggcg
    30841 cctacagaac caatggcgga tttccaacaa gcttcacaaa ataaaccgaa attagcagat
    30901 cgtttccgtg gcttgatcgg aagcatgttt gacgaataaa gaggaaaaat aaattatgac
    30961 attttcattt gatacagctg ctgctcaagg ggcagtgatt aaagtaattg gtgtcggtgg
    31021 aggtggtggc aatgccatca accgtatggt cgacgaaggt gttacaggcg tagaatttat
    31081 cgcagcaaac acagatgtac aagcattgag tagtacaaaa gctgagactg ttattcagtt
    31141 gggacctaaa ttgactcgtg gtttgggtgc aggaggtcaa cctgaggttg gtcgtaaagc
    31201 cgctgaagaa agcgaagaaa cactgacgga agctattagt ggtgccgata tggtcttcat
    31261 cactgctggt atgggaggag gctctggaac tggagctgct cctgttattg ctcgtatcgc
    31321 caaagattta ggtgcgctta cagttggtgt tgtaacacgt ccctttggtt ttgaaggaag
    31381 taagcgtgga caatttgctg tagaaggaat caatcaactt cgtgagcatg tagacactct
    31441 attgattatc tcaaacaaca atttgcttga aattgttgat aagaaaacac cgcttttgga
    31501 ggctcttagc gaagcggata acgttcttcg tcaaggtgtt caagggatta ccgatttgat
    31561 taccaatcca ggattgatta accttgactt tgccgatgtg aaaacggtaa tggcaaacaa
    31621 agggaatgct cttatgggta ttggtatcgg tagtggagaa gaacgtgtgg tagaagcggc
    31681 acgtaaggca atctattcac cacttcttga aacaactatt gacggtgctg aggatgttat
    31741 cgtcaacgtt actggtggtc ttgacttaac cttgattgag gcagaagagg cttcacaaat
    31801 tgtgaaccag gcagcaggtc aaggagtgaa catctggctc ggtacttcaa ttgatgaaag
    31861 tatgcgtgat gaaattcgtg taacagttgt tgcaacgggt gttcgtcaag accgcgtaga
    31921 aaaggttgtg gctccacaag ctagatctgc tactaactac cgtgagacag tgaaaccagc
    31981 tcattcacat ggctttgatc gtcattttga tatggcagaa acagttgaat tgccaaaaca
    32041 aaatccacgt cgtttggaac caactcaggc atctgctttt ggtgattggg atcttcgccg
    32101 tgaatcgatt gttcgtacaa cagattcagt cgtttctcca gtcgagcgct ttgaagcccc
    32161 aatttcacaa gatgaagatg aattggatac acctccattt ttcaaaaatc gttaagtaaa
    32221 tgaatgtaaa agaaaataca gaacttgttt ttcgagaagt tgcagaggct agtctgagtg
    32281 ctcatcgaga gagtggttcg gtctctgtca ttgcagttac caagtatgta gatgtaccga
    32341 cagcggaagc cttgcttccg ctaggtgtcc atcatatcgg tgaaaatcgt gtagataagt
    32401 ttctggaaaa atatgaagct ttaaaagatc gagatgtgac ttggcatttg attggtacct
    32461 tgcaaagacg taaggtgaaa gatgtcattc aatacgttga ttatttccat gcattggact
    32521 cagtaaagct agcaggggaa attcaaaaaa gaagtgaccg agtcatcaag tgtttccttc
    32581 aagtaaatat ttctaaagaa gaaagcaaac acggtttttc gagagaggaa ctgctggaaa
    32641 tcttgccaga gttagccaga ctagataaga ttgaatatgt tggtttaatg acgatggcac
    32701 cttttgaggc tagcagtgag cagttgaaag agattttcaa ggcggcccaa gatttacaaa
    32761 gagaaattca agagaaacaa attccaaata tgcctatgac cgagttaagt atgggaatga
    32821 gtcgtgatta taaagaagcg attcaattcg gttccacttt tgttcgtata ggtacatcat
    32881 tttttaagta ggagagaacc atgtctttaa aagatagatt cgatagattt atagattatt
    32941 ttacggagga tgaggattca agtctccctt atgaaaaaag agatgagcct gtgtttactt
    33001 cagtaaattc ttcacaggaa ccggctctcc caatgaatca accttcacag tcggctggga
    33061 caaaagagaa caatatcacc agacttcatg caagacaaca ggaattggca aatcagagtc
    33121 agcgtgcaac ggataaggtc attatagatg ttcgttatcc tagaaaatat gaggatgcaa
    33181 cagaaattgt tgatttattg gcaggaaacg aaagtatctt gattgatttt cagtatatga
    33241 cagaggtgca ggctcgtcgt tgtttggact atttggatgg agcttgtcat gttttagctg
    33301 gaaatttgaa aaaggtagct tctaccatgt atttgttgac accagtgaac gttattgtaa
    33361 atgttgaaga tatccgttta ccagatgaag atcaacaggg tgagttcggt tttgatatga
    33421 agcgaaatag agtacgataa tgattttttt aattcgtatg atttataatg cagtggatat
    33481 ttactcccta attttggtag ccttcgctgt catgtcttgg tttccaggtg cctacgaatc
    33541 cagtttaggt cgttggattg tagcgttggt aaaaccagtg cttgctccct tgcaacgcct
    33601 gcctttacag atagcgggtc ttgatttatc tgtttgggtc gcgattgttt tggttcgatt
    33661 tttaggagaa aacctagtgc gttttctggc gatgatagga tgaataaagg gatttatcag
    33721 catttctcca tagaagatcg tccatttctt gacaagggaa tggaatggat aaagaaggta
    33781 gaagatagct atgctccttt tttaactcct tttatcaatc ctcatcagga gaagctatta
    33841 aagattttgg ccaaaaccta tggtcttgct tgtagcagta gtggggaatt cgtctcgagt
    33901 gagtatgttc gagttttatt atacccagat tatttccaac cagagttttc agattttgaa
    33961 atatctctcc aggaaattgt gtattccaat aaatttgaac atttaacgca tgctaagatt
    34021 ttagggacag tcatcaatca attagggatt gaacggaaac tttttggaga tatcctagta
    34081 gatgaagaac gggcgcagat tatgattaat cagcagtttc ttcttctctt tcaagatgga
    34141 ctaaagaaaa ttggtcgtat acctgtttcg ctggaggaac gtcctttcac cgagaaaata
    34201 gataagctag aacagtatcg agaactggat ttatctgtgt ctagttttcg attagatgtt
    34261 cttttatcaa atgttttgaa actatctagg aatcaagcaa accagttgat tgaaaagaaa
    34321 cttgtccaag taaattatca tgtggtagac aaatcagatt acactgttca agttggagac
    34381 ttgattagtg tgagaaaatt tggtcgcttg agattacttc aagataaggg acaaacgaaa
    34441 aaagagaaga aaaaaataac cgtccagtta ttattaagta agtgaggaat agaatgccaa
    34501 ttacatcatt agaaataaag gacaagactt ttggaactcg attcagaggt tttgatccag
    34561 aagaagtcga tgaattttta gatattgtgg ttcgtgatta cgaagatctt gtgcgtgcga
    34621 atcatgataa aaatttgcgt attaagagtt tagaagagcg tttgtcttac tttgatgaaa
    34681 taaaagattc attgagccag tctgtattga ttgctcagga tacagctgag agagtgaaac
    34741 aggcggcgca tgaacgttca aacaatatca ttcatcaagc agagcaagat gcgcaacgct
    34801 tgttggaaga agctaaatat aaggcaaacg agattcttcg tcaagcaact gataatgcta
    34861 agaaagtcgc tgttgaaaca gaagaattga agaacaagag ccgtgtcttc caccaacgtc
    34921 tcaaatctac aattgagagt cagttggcta ttgttgaatc ttcagattgg gaagatattc
    34981 tccgtccaac agctacttat cttcaaacca gtgatgaagc ctttaaagaa gtggttagcg
    35041 aagtacttgg agaaccgatt ccagctccaa ttgaagaaga accaattgat atgacacgtc
    35101 agttctctca agcagaaatg gaagaattac aagctcgtat tgaggtagcc gataaagaat
    35161 tgtctgaatt tgaagctcag attaaacagg aagtggaaac tccaactcct gtagtgagtc
    35221 ctcaagttga agaagagcct ctgctcatcc agttggccca atgtatgaag aaccagaagt
    35281 agctccagtg catccgacag gtccaacacc agctacagaa actgttgatt cagcaccagg
    35341 atttgaagca ccgcaagaat ccgttacaat tttataagaa acgatgtgag aacaatatct
    35401 tatccttata tttccagcga gcaggagatg gtgtgagtcc tgcattccct aacgataaga
    35461 ttatcctctc aaaaactcaa gtctgaatct agtaagattt gacgtttccc acgttacggg
    35521 ataagaggga gaaagactaa atctttttcc gaataaaggt ggtaccacga ttttcgtcct
    35581 ttttggaagt cgtggttttt aatttgttat tatttataaa ggagatacca tgaaactaaa
    35641 agataccctt aatcttggga aaacagcttt cccaatgcgt gcaggccttc cgaccaaaga
    35701 gccagtttgg caaaaggaat gggaagatgc aaaactttac caacgtcgtc aagaactaaa
    35761 tgaagggaaa ccgcattttg tcttgcatga tggccctcca tacgcaaacg gaaatatcca
    35821 cgttggacat gccatgaatc atatctcaaa agatatcatc attcgttcta agtctatgtc
    35881 aggttttaac gcaccttata tcccaggttg ggatactcat ggtctgccaa tcgagcaagt
    35941 tttggcaaag caaggtgtga agcgcaaaga aatggacttg gttgagtact tgaaactctg
    36001 tcgtgagtac gctctttctc aagtttataa acaacgtgat gatttcaaac gcttggggat
    36061 gtcaggtgac tgggaaaatt tatatgtgac tttaactcca gactatgaag cagcccaaat
    36121 ccgtgtcttt ggtgagatgg ctaataaggg ttatatctac cgtggtgcta agccagttta
    36181 ctggtcatgg tcatctgagt cagcccttgc cgaagcggaa attgaatacc atgatttggt
    36241 ttcgacttca ctttattatg ccaataaggt aaaagatggc aaaggtatcc tagatacaga
    36301 tacttatatc gtagtctgga caacaactcc atttaccatc acagcttctc gtggtttgac
    36361 tgttggtgca gatattgatt acgttttggt tcaacctgct ggtgaaactc gtaagtttgt
    36421 cgttgctgca gaattgttga ctagcttgtc tgagaaattt ggctgggctg atgttcaagt
    36481 gttggcaact taccgtggtc aagaactcaa ccacatcgta acagaacacc catgggatac
    36541 agctgtagat gagttggtaa tccttggtga tcacgttacc actgactctg gtacaggtat
    36601 cgtccataca gcccctggtt ttggtgagga cgactacaat gttggtattg ctaatggtct
    36661 tgaagtcgca gtgactgttg acgaacgcgg tatcatgatg gcgaatgctg gtcctgagtt
    36721 tgaaggtcag ttctacgaca aggttgtacc aactgttatt gaaaaacttg gtaacctcct
    36781 tctagcccaa gaagaaatct ctcactcata cccatttgac tggcgtacta agaaaccaat
    36841 catctggcgt gcagttccac aatggtttgc ctcagtttca aaattccgcc aagaaatctt
    36901 ggatgctatt gataaagtta aattccatac agaatggggt aaagtacgtc tatataatat
    36961 gattcgtgac cgtggtgact gggttatctc tcgtcaacgt gcttggggtg ttccacttcc
    37021 aatcttctat gcagaagacg gtacagctat catgacagct gagactattg aacatgtggc
    37081 gcaactcttt gaagtacatg gttcaagcat ttggtgggaa cgtgatgcca aggacctctt
    37141 gccagaagga tttacacatc caggttctcc aaatggggag ttcaagaaag aaacagatat
    37201 tatggatgta tggtttgact caggttcatc atggaatggt gttttggtaa atcgtccaaa
    37261 tctgacttat ccagctgacc tttaccttga aggttctgac caataccgtg gttggttcaa
    37321 ctcatcactc attacatctg ttgccaacca tggcgtagca ccttacaaac aaatcttgtc
    37381 acaaggtttt acccttgatg gtaaaggtga gaagatgtct aaatcacttg gcaataccat
    37441 tgctccaagt gatgttgaaa aacaatttgg tgcagaaatc ttgcgtctct gggtaacaag
    37501 tgttgactca agcaatgacg tgcgtatctc tatggatatt ttgagccaag tttctgaaac
    37561 ttaccgtaag attcgtaaca ctcttcgttt cttgattgcc aatacatctg actttaaccc
    37621 agctcaagat gtagtcgctt acgatgagct tcgttcagtt gataagtaca tgacgattcg
    37681 ctttaaccag cttgtcaaga ccattcgtga tgcctatgca gactttgaat tcttgacgat
    37741 ctacaaggcc ttggtgaact ttatcaacgt tgacttgtca gccttctacc ttgattttgc
    37801 caaagatgtt gtttacattg aaggtgccaa atcactggaa cgccgtcaaa tgcagactgt
    37861 cttctatgac attcttgtca aaatcaccaa actcttgaca ccaatccttc ctcacactgc
    37921 ggaagaaatt tggtcatatc ttgagtttga aacagaagac ttcgtccaat tgtcagaatt
    37981 accagaggct caaacttttg ctaatcaaga agaaatcttg gatacatggg cagccttcat
    38041 ggacttccgt ggacaagctc aaaaagcctt ggaagaagct cgtaatgcaa aagtaatcgg
    38101 taaatcactt gaagcacact tgacagttta tccaaacgaa gttgtgaaaa ctctactcga
    38161 agcagtaaac agcaatgtgg ctcaactttt gatcgtgtca gacttgacca tcgcagaagg
    38221 accagctcca gaagctgccc ttagcttcga agatgtagcc ttcacagttg aacgcgctgc
    38281 aggtgaagta tgtgaccgtt gccgtcgtat tgacccaaca acagcagaac gtagctacca
    38341 ggcagttatc tgtgaccact gtgcaagtat cgtagaagaa aactttgcag atgcagtcgc
    38401 agaaggattt gaagagaaat aagattgaaa agtctaggca aaattcaatt tgagaagaaa
    38461 agacaactaa ttttatagtc tattaaacgc attgtatcac gtttttgaac acctgatatg
    38521 atgcgttttt tatttttaaa atttgcaagg tgtgactttt tatactcata ctcaatgaaa
    38581 atcaaaaagc aaactaggaa gctagccgca ggctgctcaa aacactgttt tgaggttgta
    38641 gataagactg acgaagtcag taacatatat atggtaaggc gacgctgacg tggtttgaag
    38701 agattttcga agagtatcaa caagaatcaa agagaaactt agcaagctaa cagtagtaag
    38761 ataaaatagg aatttgatat tagggataag attggtaaat agtgtaatat ttttacaaca
    38821 ataaatttat atagttattt ctggtttctg aaaagtatta tattatattt tatttcatat
    38881 tatacaaatt tttattttat aatatcagaa aatacttttt ttaaaaagca aatatgatat
    38941 aattttattt gaaaaaaaat aaaaaaggag attttattat gaaatcaagt ggtatcgtcg
    39001 gtcttgtggg aggaatttta cttcttattt gtccttttgt cttgttggga acagcggtaa
    39061 atacagctgc tacaactctt aatggaggag ctactgcagg ggctttttca ggtgttgcct
    39121 tactcttgaa taccttgaag attgcaaatc ttgttcttgg tatcattgct attgtttact
    39181 ataaaggaga taagcatgta ggtgcagctc cgtctgtact aatgattgtt tctggtgaag
    39241 ttagtctcat tccattctta ggatgggttg gggggattct tgctattatc ggaggatctc
    39301 tattccttgc aacattgaag aaattcaaat cagaagaata aaaggtattt tagcatgaaa
    39361 agaacaaaaa agtttatcgg tataggagta gctctattat ctctttctct tctagttgca
    39421 tgtggaacat aaagttcaaa gaatacttca acaagtaatg atgagaagac agtagcaaca
    39481 tccaatagtt caaaagaaac aatcactttc gatacaccgg ttgtaacaga cgatgcgatt
    39541 gaatcaatac gcacttatgc agattatata gatctttata aaaatatttt tgatgattat
    39601 tttactaaag ctgaggaagg tttcaaaggc acagctatgg aaaataatga ctcgtttact
    39661 aaactaaaag agtcaactca aaaattattc gatgcgcaga aaaaaaggtt aaataaatga
    39721 agatagaata gaaacaacca aaaacaatgt gattgccaaa cattgtcaaa cagtcctttc
    39781 ctttttggtt ttgactagct tttttgtgaa aaattgtgta aaatagaata gataaacgag
    39841 gggaaacctc ggaaaattta aaggagaatc catctaatgg taaaattggt ttttgctcgc
    39901 cacggtgagt ctgaatggaa caaagctaac cttttcactg gttgggctga tgttgatttg
    39961 tctgaaaaag gtacacaaca agcgattgac gctggtaaat tgatcaaaga agctggtatc
    40021 gaatttgacc aagcttacac ttcagtattg aaacgtgcta tcaaaacaac taacttggct
    40081 ctcgaagctt ctgaccaatt gtgggttcca gttgaaaaat catggcgctt gaacgaacgt
    40141 cactacggtg gtttgactgg taaaaacaaa gctgaagctg ctgaacaatt tggtgatgag
    40201 caagttcaca tctggcgtcg ttcatacgat gtattgcctc caaacatgga ccgtgatgat
    40261 gagcactcag ctcacacaga ccgtcgttac gcttcacttg acgactcagt tatcccagat
    40321 gctgaaaact tgaaagtgac tttggaacgt gctcttccat tctgggaaga taaaatcgct
    40381 ccagctctta aagatggtaa aaacgtattc gtaggagctc acggtaactc aatccgtgcc
    40441 cttgtaaaac acatcaaagg tttgtcagat gacgagatca tggacgtgga aatccctaac
    40501 ttcccaccat tggtattcga attcgacgaa aaattgaacg tcgtttctga atactacctt
    40561 ggaaaataaa aaattgtaag tctagaattg atttctaggc tttttatgtt agtatggaag
    40621 tatgataagg aataaaaaac aagattatgt actggcctac aagcaaccag cttcaaccac
    40681 ttacatgggt tgggaggaag aagctttacc gataggcaat ggttctttag gagcaaaagt
    40741 atttggcctt ataggggctg aacggattca atttaatgaa aaaagtctct ggtctggagg
    40801 tccacttcct gatagttcag attatcaggg tggaaatctt caggatcagt atgttttttt
    40861 agctgagatt cggcaggctt tggagaagag agattacaat ctggctaagg aactggctga
    40921 gcagcaccta attgggccaa aaacgagtca atatgggacc tatctgtctt ttggggatat
    40981 tcacattgag ttcagccagc aaggtacgac tttgtctcag gtgacggact atcagagaca
    41041 gttgaatatt agtaaggcac ttgcgacgac ttcttatgtc tataagggaa cgcgatttga
    41101 acgtgaagct tttgcgagtt ttccagatga tctcttggtt caatgtttta ctaaggaagg
    41161 gttggaaact ctagatttta ctatagaact atccttgacc tgtgatttgg cttctaatgg
    41221 aaagtatgag caggaaaaat ctgattacaa ggagtgtaag ttggatatta ctgattctca
    41281 tatcttgatg aagggaagag ttaaggataa tgatctgcgg tttgctagtt atctagcttg
    41341 ggaaacggat ggagatatta gagtttggtc agatagggtt cagatatcag gagccagtta
    41401 tgccaatctc ttcttggccg ctaagacgga ttttgcccaa aatcctgcta gcaattatcg
    41461 caagaaacta gatttagagc aacaggtgat agacttggtg gacacagcta aagaaaaggg
    41521 ctatacccaa ttgaaatcaa ggcatatcga ggactaccaa gccttattcc agcgtgttca
    41581 attggatttg gaagctgatg ttgacgcatc cactacagat gatttgttaa aaaattataa
    41641 gccacaagaa gggcaggctt tggaggagct gttcttccag tatggacggt atttattgat
    41701 tagttcgtcc agatactgcc cagatgctct accagctaac ctacagggag tctggaatgc
    41761 ggtcgacaat cctccttgga attcggacta tcacttaaat gtcaatctgc agatgaatta
    41821 ttggccagcc tatgttacca atcttctaga gacggtcttt ccagtcatca attatgtaga
    41881 tgatttgcgt gtctatggtc gtctagcggc tgtaaagtat gcaggaatcg tctctcagaa
    41941 aggtgaggag aatggttggt tggttcatac tcaagcgact ccctttggtt ggacggcacc
    42001 tggttgggat tactattggg gttggtcacc agctgccaac gcgtggatga tgcaaaccgt
    42061 ttatgaagcc tattcatttt atagggacca agactatctc agggagaaaa tttatcccat
    42121 gttgagggaa acggttcgtt tttggaatgc ctttttacat aaggatcagc aggcgcagcg
    42181 ttgggtgtct tctccgtctt attccccaga acatgggccg atttcgattg gcaataccta
    42241 tgaccaatct ctgatttggc agttatttca tgattttatt caggctgctc aggaattggg
    42301 actggatgag gacttgttga ctgaggttaa ggagaagtct gatttactaa atcctttgca
    42361 aatcactcaa tctggtcgaa tcagggagtg gtatgaggag gaagagcagt attttcaaaa
    42421 tgagaaagtg gaggcccagc atcggcacgc ttcccatcta gtgggactct atcctggcaa
    42481 tctctttagc tacaagggac aagagtatat tgaagcggcg cgtgctagcc tcaatgatcg
    42541 tggagatggc ggcacaggct ggtccaaggc taataagatc aatctctggg cgcgtttggg
    42601 agatggtaat cgagcccata aattattggc agagcagtta aagacatcca ccttgccaaa
    42661 tctttggtgt agccatcctc cttttcagat agatggtaat tttggtgcta ctagtggcat
    42721 ggcagaaatg ttactccagt ctcatgcagc ttatctggta cctctagctg ccttacctga
    42781 tgcttggtca acaggttctg tttcaggctt aatggcacgt ggacattttg aagttagcat
    42841 gagctgggaa gataaaaaac tcttacagtt gaccatttta tcaaggagtg gaggagattt
    42901 gcgagtttct tatccagata ttgagaagag tgtgattaaa atgaatcaag aaaaaataaa
    42961 agcgaaatgc atggggaaag attgtatttc ggtggcaaca gcagaaggtg atcttgttca
    43021 attttatttt taagaagatg ttataaggca gtaatttgaa actgcctttt aataaggatt
    43081 taagaatgta agcagtttcc aactagttga aaaagcgtta taatgataat aggaagtaat
    43141 actcaatgaa aatcaaagag cacaaactag gaagctagcc gcaggttgct caaaacagtg
    43201 ttttgaggtt gcagatggaa gctgacgtgg tttgaagaga gattttcgag gagtataatt
    43261 tgtttgatag agggtgggtc tgatggctta tattgagatg aaacactgtt acaagcgtta
    43321 tcaggttggg gacacggaga ttgtggccaa tcgtgatgtg aattttgaga ttgaaaaggg
    43381 ggagctggtt attatccttg gtgcttcagg tgcaggtaag tcaacagttc ttaaccttct
    43441 tgggggaatg gataccaatg atgaagggga aatctggatt gatggtgtta atattgcgga
    43501 ttatagttcc caccagcgca ccaattaccg tagaaatgat gtggggtttg tttttcagtt
    43561 ttataatcta gtttctaatc tgacagctaa ggaaaatgtg gaattggctt ctgaaattgt
    43621 gacagatgcc ttgaatcctg atcaggtctt gacagatgta ggtctggctc atcgtctcaa
    43681 taactttcca gcccagcttt ctggagggga gcaacagcga gtctccattg cacgcgcggt
    43741 agccaaaaat cctaaaattc ttctttgtga tgaacctact ggagccttgg attatcagac
    43801 gggcaagcag gttttgaaaa ttctccaaga tatgtctcgt caaaagggag cgacggtgat
    43861 catcgtgact cataatggag ctttggcgcc cattgctgat cgcgtgattc atatgcacga
    43921 tgccagtgtc aaggatgtgg tgctcaacca gcatcctcag gatattgaca gtttggagta
    43981 ctagtatgat caagcgaaaa acttattgga aggacttaat tcagtccttc acaggctcca
    44041 aggggcgttt tttatccatc ttgatcctga tgatgttggg atctctagcc ttagtaggcc
    44101 tcaaagtaac cagtcccaac atggaggcga cagctaatgc ttatttaaca actgctcaaa
    44161 ccttggattt ggcagtcatg tctaactatg gcttggatca agcagaccaa gaagaactaa
    44221 aacagacgga gggcgcagag gtcgagtttg gctatttgac agatgtgact atggataatg
    44281 ggcaggatgc cattcggctg tactccaaac cagagcgaat ttcaaccttt cagctaagaa
    44341 agggacgact tcctcagtca gacaaggaaa tcgctttggc cactcatttg caaggccaat
    44401 acagcgtggg acaggagatt agttttaaag aaaaagaaga gggtcattcc tctttaaaag
    44461 accatactta taccattact ggttttgtgg attcggctga aatcctctcc cagcgagata
    44521 tgggctacgc aggaagtgga agtgggactc tgacagccta tggggtgatt ttacctagtc
    44581 agtttgatca gaaagtctac aatatagctc gtttgaaata tcaagattta gcaggtttaa
    44641 atgccttttc atcagcttat gaagaaaaat ccaagcaaca tcaggaagag cttgaacaaa
    44701 ttttatcaga taatggcaag gtacgtctgc aacttttgaa aaaagaagga caagagtctc
    44761 tagacaaggg gcaagagacc cttgacaagg ctcagactaa tttgcaggaa ggcaagcgtc
    44821 gtttagcagc tgctcaagct cgtatacagg ctcaagaaag tcaactagcc ttgtttcctc
    44881 aagttcagag agagcaggct agtgctcaac ttacccaagc caagcaggaa ttgggcaagg
    44941 aagaggccaa actaaagcaa gctgaacaaa atctagccca agaaaatgaa aaattagaaa
    45001 aacatcagca agtcttggac gatttggcgg agccaaggta tcaggtctat aatcgtcaga
    45061 ccatgccagg tggtcagggc tatcttatgt atagcaatgc ttcatccagt attcgagcag
    45121 tgggcaatat ctttcctgtg gtactttatg ccgtagcagc catggtgacc tttacgacca
    45181 tgactcgctt tgtagacgaa gagcgaactc atgcagggat ttttaaggcc ttgggttatc
    45241 gtagtaagga tattatcgcc aagtttctcc tttatggact agtagctggg actgtcggaa
    45301 cggctctagg tagtatactt ggtcattatt tgctagccag tgtaatttca agtgtcatta
    45361 caaaaggcat ggtggtggga gaaactcaga ttcagttcta ttggacctat agcttactag
    45421 ctcttgtctt gagcttgttg gcgagtgtgt taccagccta tctggtggct tggagggaac
    45481 ttcatgacga agcagcccag cttctacttc ctaaacctcc tgtcaaagga gctaaaatct
    45541 tattggagcg tatcggtttt atctggcgtc gtctcagttt tactcataag gtaacagccc
    45601 gcaacatctt tcgttataag cagagaatgt tgatgacaat ctttggtgtg gcaggttctg
    45661 tagctctgct ctttgcaggt ttgggaatcc aatcttctgt agcaggagtt ccgtctaaac
    45721 agtttcaaca aatccaacag tatcagatgc ttgtctctga aaatcctagt gcgaccaatc
    45781 aggacaaggt agagctagca gaagtgttga aagggcagga gatactagcc taccagaaaa
    45841 tctattctaa aacgctagac aaggatttca aaggcaaggc tggtcttcaa aacattactc
    45901 ttatgatgat agagaaggaa gatttgactc cctttatcca tcttcaacat catcagcagg
    45961 agctgacatt aaaagatggc atcgttatta cagctaaact cgcccagctg gcaggtgtca
    46021 aggttgggca gactttagaa attgaaggta aggaactaaa ggtcgctgct attactgaga
    46081 actacgttgg tcactttatt tatatgagtc aggctagcta tgagcaactt tacggacagc
    46141 taccccaagc caacacttat ctggtctcat taagggatac cagtgcaact agtatcgaaa
    46201 gtcaggcggg cttgcttatg aatcaatctg cggtgtccag cgttgtccaa aatgcttcag
    46261 ccattcgact cttcgactct atcgctagct cactcaatca gaccatgacc atcttggtca
    46321 tcgtatctgt tctattagct attgtcatcc tttacaatct gaccaatatc aacgtagctg
    46381 agagaatccg tgaactctcc actatcaagg ttctcggttt tcataataat gaagtcacac
    46441 tctacattta ccgtgagacg attgtgctgt cccttgtggg aatcgtactt ggtctgatag
    46501 ctggtttcta tttacaccaa tttttgattc aaatgatttc gcctgcgact attctctttt
    46561 atccgcaggt aggctgggaa gtctatgtaa tcccagtggc agcagtaagc atcattttga
    46621 ccttgcttgg tttcttcgtc aattattatc tgagaaaggt tgatatgtta gaagctctga
    46681 aatctgtaga gtaaggtagt tatttttagc tgattgaact tctatttact aatattcaaa
    46741 aatcctccgt ttcaaagagc agggaactct ttgtgacaga ggattttttc tatagggctt
    46801 tagcagctgc aattgcggct tcgaagtttg gctcagaatt gatattatcc acgtattcaa
    46861 cgtagcgaat cgtattgtca gtatcgagga caaagactgc gcgtgctaat aggtgccatt
    46921 cgttgattaa gagggcataa tcgtgcccga aagaatggtc aaagtagtct gaaagcataa
    46981 tggcattgtc aaggccttca gcaccgcacc aacgtttttg agcaaaaggt aggtccattg
    47041 aaacagtcaa tacgaccgtg ttgtccagtc cagccaattc ttcattaaaa cgacgtgttt
    47101 gagttgagca gatgcctgta tcgatagaag gaacgacact caagactttt ttcttgccat
    47161 caaaatcagc cagagatttt ttagaaagat ctgttgtagt aagagaaaaa tcaagcgcct
    47221 tgtcgccaac ttgtagttgt ttacctgtaa agctcacagg atttccgaga aaagttacca
    47281 taggatactc caatcttttt tcttccattg tatctgaaac agtcagaatt ttccaatgat
    47341 ttgaccggaa atgtgggcat agaaaaaacg ccagctcaca tgagaatgac gtttttcaga
    47401 ggcttatttt gccaatcctt cagcaatctt gtcaaggttg tatttcatca tgctgtagta
    47461 gctgtcgcct tctttacctt gttctgcgat agagtcagta aagatttgtg cgtagattgg
    47521 gatgtttgtg tcttgagaaa cagttttcat tggacggtca tccacacttg attctacaaa
    47581 gagtgatgga acttttgttt ggcgaagttt ttcaaccaag gtcttgattt gttcaggagt
    47641 tccttcttct tcagtattga tttcccagat gtaggcactt gggacaccat aggctttaga
    47701 gaagtatttg aatgctcctt cgctggttac aatgagtttc ttttcagcag ggatcttatt
    47761 aaatttatcc ttactttctt tatcaagttt gtctaactta tcagtatatt ctttgagatt
    47821 tttttcatag aattctttat tgttagggtc tttggcgctc aattgtttgg cgatattttt
    47881 agcaaaaata ataccgtttt caaggttaag ccaagcgtgt gggtcttctt ttcctttttc
    47941 attttgacct tcaaggtaga taacatcaac gccgtcgctg actgcgaagt agtctttgtt
    48001 ttcagttttc ttggcatttt ctaccaattt tgtaaaccaa gcattgccac ctgtttcaag
    48061 gttgataccg ttatagaaaa tcaaatcagc ctcagaagtt ttcttaacgt cttcaggaag
    48121 tggttcgtat tcgtgtgggt cttgcccaat cggaacgata ctatgaaggt caattttgtc
    48181 accagcaata tttttagtaa tatcagcgat gattgagttt gtagcaacaa cttttagttt
    48241 ttgaccagaa gttgtatctt tttttccgct agcacatgct acaagaatga ttgcagaaag
    48301 aaagagaacg agtaatgtac ctaatttttt cattagatcc tccaatttat tagggctttg
    48361 ccccttattt taacaaatgt ttatttttca gtttcaaata tcgttgtttg ggagcgataa
    48421 agaagctaat gagaaagaaa ctagcagctg taagcacgat actagaacct gccgcaacat
    48481 taaaactata gccaataaag agtcccaaaa ctgaagcagt agctccgaag gttgaggaaa
    48541 ggaaaatcat acttttcaga ctattagcat acagataagc agttgcagct ggggtaatca
    48601 gcatggctac aatcaggata gttccgacac tttgcatggc tgtcacagac acgagagtca
    48661 ggagtaccat gagaaggtag tgatagaaat tgacaggcat tcccatggct ttagccaaga
    48721 gttcatcaaa ggaagttatc aagagttgct tgaagaaaat ccaaattaac aagaggatgg
    48781 ctgcccccac acccatagta ataaacatat ccgtatcttg gacggccagg atattaccaa
    48841 aaaggatatg gaaaaggtca gttgaacttt tagcgacacc aatcaagatg ataccgaggg
    48901 ctaagaaaga agaaaaggta atgccgatgg cggtatcgct tttgataatc gagtttcctt
    48961 tgatgtaggt aatgatgatg gcagctagca atccaaagac aatggctccg ataaagaagt
    49021 caaggcccaa gatgaaggag agggctacac ctggtaagac agcatgtgaa atggcatctc
    49081 ccatgagtga catcccgcgt agaataatga aacatcccac ggctccagct acaatcccga
    49141 cgacaatagc tgttatcaag gcattttgta ggaaatggaa tttttgcaat ccatcgataa
    49201 attctgcaat cataggtcac ctccattgaa aaagagttga ttaccgtaag cttcttttag
    49261 attggtttcg gtaaaagttt cttttgttgg accaaaggca atcacttctc gattgacaag
    49321 taagacttga tcgaagtagt ggggaatctt gctgaggtcg tggtgaacga tgagaaccgt
    49381 cttcccagct tttttcaaat ctctcagcgt attcatgatg atttcctcac tgacagagtc
    49441 aatcccagca aagggttcat ccaagaggat atagtcggct tcctgcacca aacatctggc
    49501 aatcaagacc cgctggaatt gacctccaga cagttgacta atttgacgtt cagcgtagtc
    49561 agctaggccg acgatttcaa gggcctcttg cactttcttc caatgtttag cctttaaact
    49621 tcgaaagaga ggaatagagg gaaatagtcc taacgagacg cattccttga ccttgatggg
    49681 aaagttgtag tcgatattga ttttttgttc gacataggca attcggtgta aggatttttt
    49741 aacttccttg tcatcgagaa atgcctgacc ttgatgtggg ataattccca acataccttt
    49801 taatagtgtt gatttcccag cgccgtttgg accaatgatg ccggtaattg ttggtccatg
    49861 gagcactagt gaaatatcct taagtgccaa cgtttctttg taggagacac tgaggttttc
    49921 gatacgtatc ataaacttgt attcctcctg tctcttaata tacattaaaa aaaaaattaa
    49981 gtcaagttaa tttttgaaaa aattaaaata ataactgaaa aatagattct aaaaataact
    50041 ttcaggataa atttctaaat tataaaacgc atagtatcaa gtgtaaaaaa cttggaatta
    50101 tgcgttttat catggaaagg ttttttataa tagctaaaaa ataatagtta aatggttatt
    50161 aattgcattc cctagtgatt tttgttaaga taaaggcaaa tacaaatgaa agcgagaaca
    50221 agatgacacg ttatcaagat gatttttatg atgctatcaa tggagaatgg caacagacag
    50281 ctgaaatccc agcagataag tctcaaacag gaggttttgt tgatttagac caggaaattg
    50341 aagacctgat gctggcgaca acagacaagt ggttagcagg tgaagaagtg cctgaggatg
    50401 ctatcttgga aaactttgtc aaataccacc gcctagttcg tgattttgac aagagagaag
    50461 ctgacggtat cacacctgtc ttaccactcc ttaaagaatt ccaagaattg gaaacttttg
    50521 cggattttac agctaaacta gcagagtttg agcttgcagg aaaaccaaac ttccttcctt
    50581 ttggtgtatc gccagacttt atggatgcta gaatcaatgt tctatgggct agcgctccaa
    50641 gcacaatctt gccagatacg acctactatg cagaagaaca tcctcagcgc gaagagctct
    50701 tgactctttg gaaagaaagt agcgcaaatc tcctcaaggc ttatgatttc tctgatgaag
    50761 aaattgaaga cttgctagaa aaaagacttg aattggaccg ccgagttgcg gcagtggtgc
    50821 tctctaatga agaacgttca gaatatgcta aactctatca tccatattct tacgaagatt
    50881 tcaagaaatt cgcgcctgcc ctacctttgg atgacttctt caaagcagtt attgggcaat
    50941 taccagacaa ggttattgta gacgaggaac gtttctggca agcagcagag caattttaca
    51001 gtgaggaagc ctggtctctc cttaaagcaa ccttgatttt gagtgttgtc aatctttcaa
    51061 ccagctattt aacagaggat atccgtgttt tgtctggtgc ctacagccgt gccctttctg
    51121 gagttccaga ggcaaaagat aaggtcaaag cagcttatca tctagcacag gaacctttca
    51181 agcaagccct ggggctttgg tacgcccgtg agaagttctc tccagaagcc aaggcggatg
    51241 tggagaaaaa agtggcaacc atgattgatg tctataagga gcgtctgctt aagaatgact
    51301 ggctcactcc agaaacctgt aaacaggcta tcgtgaagct caatgtgatc aaaccttata
    51361 ttggctatcc agaagaattg cctgcacgtt acaaggataa ggtagtgaat gaaactgcca
    51421 gtctttttga gaatgctcta gcctttgcgc gtgtggaaat caagcacagt tggagtaagt
    51481 ggaaccagcc tgtagactat aaggaatggg gcatgcctgc tcatatggtc aatgcctact
    51541 acaatcctca gaagaacctg attgtctttc cagcggccat tttacaggcg cctttctatg
    51601 acttgcatca gtcatcttct gctaactacg gtggtattgg ggcagtgatt gcccatgaaa
    51661 tttcccacgc ctttgatact aacggggctt cctttgacga aaatggtagc ctcaaggatt
    51721 ggtggacaga gagcgactat gctgccttca aggagaaaac acaaaaagtc attgaccaat
    51781 ttgatggaca ggattcttat ggagcaacca ttaacggtaa attgactgta tcagaaaacg
    51841 tggctgactt gggaggaatc gcagcagctc ttgaagcagc taagagagaa gcagacttct
    51901 cagcagaaga gttcttctac aacttcggtc gcatctggcg catgaaaggt cgaccagaat
    51961 ttatgaaact tttggctagc gtcgatgtgc acgcaccagc caaactccgt gtcaatgtgc
    52021 aagtaccaaa cttcgacgat ttctttacaa cctatgatgt caaagaagga gacggaatgt
    52081 ggcgttcacc agaggagcgc gtgattattt ggtaatgcaa aaaatctagt catcagaaaa
    52141 aaggcatcca atcacgtgtg aaaaccttga taggatgcct tttataatag aaagatttgc
    52201 tggatagttt acttaaattt cgattgtcat catcttgcta aaaaaaggga ttgaaggctt
    52261 tttcgtgagc gatagtagta gctggaccat gtcctggata gacatcgtag tttggtaggg
    52321 tgaagagttg ggtctggata ctatgaagga gttgctccat gctaccagtc ggaaggtcgg
    52381 tccgtccgat agtttcgcgg aatagagcat ctcccgtcaa gactaggtaa gcatcaggaa
    52441 agactaggga aacaccaccg atagagtgcc ctggggtcgg tagaacctta aaacgaaatt
    52501 cctctagttg gtattcttcg tgaaagacaa aggtgtgttc tgcaggtttt gtgaccacat
    52561 ctgccatatc atcgtggcga gggagaccgg agagattatc gacaggagtg tagagccagc
    52621 tggcttcgct ctctgcgata tagacaggag gattgccaaa cgtctcgcga accaagtcca
    52681 gactcatgat atggtcataa tgggcgtggg tcaagagaat agcacagatc ggtttgttga
    52741 tcttctcgat tgtctgacga atggcttccc aatgactacc aggatcgacg acgatgaggt
    52801 gcttttcgcc ttctagataa taggtatttt cataggcaac aggattcacg gttttatgga
    52861 ttttcatact agctccaatc tcaaagaatg tactaatact cttcgaaaat ctcttcaaac
    52921 cgcgtcaact ttatctgcaa cctcaaagca gtgctttgaa cagcctgcgg ctagctttct
    52981 agtttgctct ttgattttca ttgagtataa attaagtata gcacagttag ggagaatagg
    53041 taaggattta aaatgaactt aaaaatcagc atgactagat gaagacaggc tggttatcaa
    53101 tttatcaata ttggaaaggt gtcaattgcc cttcataggt tgcataaact ccgtcattag
    53161 cttgtttgat agacgtgatg tttagagtgc taccgtagtt ggcttctcat ttgtcgctat
    53221 attcactata agttatccta ctgggcaggt tctggtcgtt agcatagtat tgaacgagtt
    53281 ttttatagct ttgctggctg aataggaaca ggcagcaaac tcctaacatt aggagagcaa
    53341 agatagaaat agcagttttt ttcataggta ttctccttat aaactaaagg atagaagaaa
    53401 gtatcttgag gatttttata ctcttcaaaa atctcttcaa accgcgtcaa ctttatctgc
    53461 aacttcaaag cggtgctttg agtaacctgc ggctagtttc ctagtttgct ctttgatttt
    53521 catttagtat taattccaaa atccagtcaa ggtaccagtg tatgtgctac gagttccacc
    53581 gtttatcttt cgtattttca atggaattgg ggaagtcaga aagtctttgg gttacaatat
    53641 ggtttccgtt cttctatctc tccttctatc acctaagttt aaaatctaac ttcgtagtat
    53701 attatgggct aataattcag aattatcaag caattttgaa ttattttttt cttattctgt
    53761 tccaatctag ttttcatatt cttaaaaaag tgataaaatg gtaggaagaa ttggagagta
    53821 gagatgccga aagaagtgaa tttaacaggc gaagaagttg tcgctttaac caaagaatat
    53881 ttaacggaag aggatgttca ttttgtccat aaggccttgg tctatgctgt tgaatgccac
    53941 agtggtcaat atcgcaaatc aggcgagcct tatatcattc accctatcca agtggcaggt
    54001 attttagcta agctaaagct ggatgctgta acagtagctt gtggattctt gcatgatgtg
    54061 gtggaagata cagatgcgac tttggacgat ttggaaagag agtttggtcc tgatgtgcgg
    54121 atgattgttg acggagttac caagcttggc aaggtcgagt acaaatcgat cgaggagcaa
    54181 ttagcggaaa atcatcgcaa gatgctcatg gccatgtctg aggacatccg cgttattttg
    54241 gtcaaactgt ctgaccgctt gcacaatatg cggaccctga aacatcttcg aaaagacaag
    54301 caggagcgta tttccaaaga aaccatggaa atctatgccc cacttgccca tcgtttgggg
    54361 atttccagtg tcaaatggga attagaagac ttgtctttcc gttatctcaa tccaacggag
    54421 ttttacaaga ttacccatat gatgaaggaa aagcgcaggg agcgtgaggc cttggtggat
    54481 gaggtagtca caaaattaga ggagtatacg acagaacgtc acttgaaagg gaagatttat
    54541 ggtcgtccca agcatattta ctcaattttc cgcaaaatgc aggacaagag aaaacggttt
    54601 gaggaaatct atgatctgat tgctattcgt tgtattttag atacccaaag tgatgtttat
    54661 gccatgcttg gttacgtgca tgaattttgg aaaccgatgc caggtcgctt caaagactat
    54721 attgccaacc gcaaggccaa tggttatcag tctatccata cgactgttta tggaccaaaa
    54781 gggccgattg aattccagat tcgaaccaag gaaatgcacg aggtggctga gtacggggtt
    54841 gcggctcact gggcttataa gaaaggtata aaggggcaag ttaacagcaa ggaatcagct
    54901 attggaatga actggatcaa ggagatgatg gagctccaag accaggctga tgatgctaag
    54961 gaatttgtgg actctgttaa ggaaaactat ttggctgagg agatttacgt ttttacccca
    55021 gatggagctg tccgttccct tcccaaagat tcaggaccga ttgattttgc ctacgaaatc
    55081 cataccaagg tcggtgaaaa agcaactggt gccaaggtca atggccgcat ggttccactg
    55141 acaaccaagt taaagacagg ggatcaggtt gaaattatcg ccaacccgaa ctcctttgga
    55201 cctagccgtg actggctcaa tatggtcaag actagcaagg cgcgcaataa gattcgccag
    55261 ttctttaaaa accaagataa ggaattgtct gtcaacaagg gtcgtgagat gctgatggct
    55321 cagttccaag aaaatggcta tgtggcaaat aaatttatgg acaagcgcca catggatcaa
    55381 gttctgcaaa agaccagtta caagacagaa gactccctct ttgcggccat tggttttggg
    55441 gaaatcggtg cgattaccgt ctttaaccgt ctgactgaaa aggaacgccg tgaggaagag
    55501 cgtgccaagg ccaaggctga ggcagaggag cttgtcaaag gtggcgaggt caaggttgaa
    55561 aataaagaaa ctctcaaggt caagcatgag gggggagtgg ttattgaagg tgcttctggt
    55621 ctcctagtgc ggattgctaa gtgttgtaac cccgtgcctg gtgacgatat tgttggctac
    55681 attaccaagg gtcgtggtgt ggctattcac cgtgtggact gtatgaacct gcgtgcccaa
    55741 gaaaactacg agcaacgtct ccttgatgtg gaatgggaag accagtactc tagctcaaat
    55801 aaggagtata tggcccatat cgatatctac ggtctcaacc gtacaggact gttgaacgat
    55861 gtactgcaag ttctttcaaa tacaaccaag aatatttcaa cggtcaatgc ccaaccaacc
    55921 aaggatatga agtttgctaa tatccatgtg tccttcggta ttgccaacct ctctacactg
    55981 accacggttg tcgataaaat taagagtgtg ccagaagttt actctgtcaa acggaccaac
    56041 ggctagttgt cctagctctt actagaaagg ctattatgaa aatcattatc caacgggtta
    56101 aaaaagccca agtgagtata gaaggccaga ttcagggaaa aatcaatcag ggacttttat
    56161 tgctggttgg tgttggacca gaggaccaag aggaagattt ggactatgct gtgagaaaac
    56221 tggtcaatat gcggattttt tcagacgcag aaggcaagat gaacctgtct gtcaaagata
    56281 ttgaaggaga aatcctctct atttctcagt ttaccctctt tgcggatact aagaaaggca
    56341 atcgtccagc ctttacaggg gcagctaaac ctgatatggc atcagacttc tatgatgctt
    56401 tcaatcaaaa attagcgcaa gaagtgcccg ttcagacagg tatctttgga gcagatatgc
    56461 aggttgagct ggttaataac ggacctgtta ccattatcct agatactaaa aagagataag
    56521 aaagaccaag cccagtcggc ttggtctttc tcatcgatca taaaatactc caaaaagaaa
    56581 tcggttcttg atatgcttgg gggaagtctc ttttcaggct ttggcagatg cgataggaag
    56641 ggatgagatg tcctaggatg aggagagttc cctgaaggaa aagtggaata tcacttaaag
    56701 acaccaagga gagaatcatc aggctatccc ataggagaat ttgtaaagca aaacgtcaga
    56761 atctcggtct aatctgggaa tagagttgac taaagtggtc acaaagttgg tttgaaagat
    56821 aggtcaatag cacaggatga aagaaaatga gccaaccact ataaatcaaa atccagtccc
    56881 aagtaagccc cccttttaaa tgtcaaaaat gccagcatga ttccatcaat gacaaggagt
    56941 tgaatggttt tgatgaagat gatttttttc atgctaaaac ctcctttttt catctgttag
    57001 tgacgtaatg ctttatataa ttattataca gtattcagtc gggatatgaa aacgtttact
    57061 atcgtttttg atataaaaaa tagataagaa aaccctgaaa ataaaacttt cagggttggt
    57121 aggggacttg agaaattagt tgattttctc gacatagagt tgttttgcaa tgtccatatt
    57181 cacttgtaaa tcctcgtcgt tactgaggat agtgaaggta ttgctgaagc catcaaactg
    57241 cttgacttgg agctggtcac cgatgtgaag tgagtgcttg tccagataat ggagaatgtc
    57301 aaaactatcg tgcacccgag tcaggcggta ggcgccagct tccttgatat cagctagtgg
    57361 gaggttattg atttcaacga ggagttctcc cttggcagga atagttcctc cgtgggggca
    57421 ggttttaggg aaacctagca gtttatctag tctttccacg aacaggtcag agacagtgtg
    57481 ttccaagacc tcagcttcct cgtgaatctg gtcacttgta tagtctaaat gatgaactag
    57541 aaaaacttca atcaagcggt gcttacgata gagctcagag accagtttga gaccgaggtc
    57601 agtcagtaga tagccacatt ccttgtcctt taggatgaga ttttcacttt tcattcgttt
    57661 gatcatttca gttacggcag ggggagagac ttgcatgcga gccgcaattt ccttgttggt
    57721 aatcttatgc aggtctatgc caatttcata aatacatttt agatagtctt ctttgtttgg
    57781 ggtcattcgt ttcctcttgt ctaatatctt tatctagtat atcaaaaaaa gctagatttc
    57841 tctagctgtg actttttatg ttatacttat tgcaagagaa aaaacgagga gatggatatg
    57901 acgaaaatag ctcttctttc agatattcat ggaaatacca ccgccttgga ggctgttttg
    57961 gcagatgctc agcagctagg agtggatgaa tactggcttt tgggagatat tctcatgcca
    58021 gggacaggac gtagaaggat tttggacttg ttggatcaac taccgattac ggctagagtt
    58081 ttgggaaact gggaagacag tctttggcat ggtgtccgta aggaattgga cagtactcgc
    58141 cccagtcaac gctatctctt gcgccagtgc cagtatgttt tagaggaaat ttccctagaa
    58201 gaaattgaag tgctccacaa tcaacctctt caaattcatc gtcagtttgg ggatttgacg
    58261 gtgggaatta gccatcatct gcctgataag aactgggggc gagagttgat tcatactggc
    58321 aaacaagagg agtttgaccg cttggtgact catcctccct gtgatattgc tgtttatgga
    58381 catattcacc agcagttgct tcgttacggg actggtgggc aattgattgt caatccgggt
    58441 tcgattggcc aacctttctt tttggacgct cagctacgga aggacttgcg ggcccagtat
    58501 atgattttgg agtttgatga caagggtctg gtagatatgg acttccgacg ggtagactac
    58561 gatgtggcag cggaattgca gctggctaaa gacctgagac ttccctattt tgaggtttac
    58621 tatgaaagtc tggtcaatgg gatccaccat actcatcatc aggaattttt gagagaattg
    58681 gctcagaaag agggctgcga tcgggagtta gacgactggt tgaaaagtgg taacgattga
    58741 cattacaact aaaaagggta taataataga aaaagaagag tagaggcagg gtagcctcgt
    58801 aaaaaggaga agaggatgca aattccaagt agatttacca ttgcgactca tatgctgata
    58861 atcattgccc tcgaggggaa ggaaagcaag gtgaccagtg attttctggc tgctagtgtc
    58921 ggggtcaatc ctgtcattat cagaaatatc ttgtcccagt tgaagaaggc agagctgatt
    58981 tcagtagcgc gtggaacggg cggaacagag attgtcaagg accttaagga tattagtctt
    59041 ttagatgttt atcaggcggt cgaatgtctt ggtaagacag gtcaactctt cagtttccat
    59101 gacaatccga atccaaattg ccctgtagga gctcatattc atgatgtttt ggatcaaaaa
    59161 ttggagagaa ttcagttgac tatggaggca gaacttggtc aaaccagtct agaaaaagtc
    59221 gtggccgatg cagagagtca gatgaaggat taagagggat aaatgccctc ttttttcttt
    59281 ggataattat gataaaatgt agctattaaa ggagtaagaa atgtatctcg ttataggaat
    59341 tgtattagcc tttatagtgt cattttggaa ggataataga agtttgtgga atccagtatt
    59401 atttttatta tccctcattt caagttattt ttatctatcc tacctttttt ataaaaatgg
    59461 atacgagaat gttcagttag ctttttatgt atttaccttt gtcttacttc cttttttgct
    59521 ttttctaagt ggcatctttt taatctataa tggggtcatt ttgttgaagt gagagggacg
    59581 ttccaagccc cattatctct caatgctctt tgatttttat tgactattag attctattta
    59641 aaaagactta gaatgcacat gaaagtatgt attctaggtc ttttgttttg tatacattta
    59701 attttcaaga gtattatcta tttttccatg cctggtaacg agtatcaatc aataactggg
    59761 taaggcgacc caaggtttct ctttcttctg gagtgaggga ttgagcttgg acaaagagat
    59821 gatgaatgta ttcaagcgcc tttaaggaag ccaagtcgtt gatagagcta ataccagcat
    59881 caagaatagt gccaaagaag aggtcgaagt agagctgaag ttcttcgtca gggactgtgg
    59941 ccacccattc tttaaaggtt gtgtctactt gctggctatc actgttggtc ttatccagtt
    60001 ggacgaagtg cttgtcctca atctgccaac taaaggtatc gtgctgggcg atgccaccca
    60061 gggcagtact ctgaacgatg atttggtgag caggaatttc cagcatcata ccgataatgg
    60121 aaccttgtgg aatgaatatc ttgcttctat ccattatcct ttgataaccc gcagtctgtg
    60181 tcaattcttg atggagacca ggtgcatcaa atgtataaac tgctgtgatc tgattttgca
    60241 aactttgctc aatttggcta gcagcataga tagcgagatt tcctcccttg gaatgcccag
    60301 ccagaataac cttttgctta ggatgatggg caaaaaagtt ctttaaatag cgaagggcgt
    60361 gcttttgagc aggaatttcc ttcatatagg tcaggtggaa atcttccttc cagccaatga
    60421 tactgtcatc tgtcccacga aagacaatca gataggtatc gaggctgaca cgataagtca
    60481 tagccgcaaa ttgcttttgc agttcagggt cgatgtcgtt gataaaatgg gagagtttgc
    60541 aatttttgaa gcgcttgtgt tgagccaatt catctaataa ttgaaggcga tttttgctag
    60601 taagcatggt gggctctctt ggaacctgag gtgctagctc taaaagacgt tgaggaagtg
    60661 tggagaccag attatcaaag gagaggtagg tgatttctat taaggttaga atgtctaact
    60721 cattcaaggg aaggtcgtaa taagaatcat atgcgacatc tttcagatag tcaaaaatat
    60781 tggccataag agctcctttc tttttattta tcttagcaaa tttccctcaa attagctagt
    60841 agcattgcct gtttgtactg gctaaaaaca ggctatttca aattcagttt cagaccatct
    60901 ggcatggaaa aatctgttat aataatggaa aaggagaagc gcatgcacaa gattttatta
    60961 gtggaagatg atcaggtcat tcgtcaacag gttgggaaaa tgctctctga atggggattt
    61021 gaagtggtcc tggtagaaga ctttatggaa gttttgagtc tatttgttca gtcggaacct
    61081 catctggtcc tcatggatat tggtttgccc ttgtttaatg gttatcactg gtgtcaggaa
    61141 atccgcaaga tttccaaggt acctatcatg tttctttctt cgagagacca ggctatggat
    61201 attgtcatgg caatcaatat gggggcggat gactttgtga ccaagccttt tgaccagcag
    61261 gttcttttag ctaaggttca gggcttgttg cgtcgttcct atgagtttgg gcgtgatgag
    61321 agtttgctgg aatatgctgg tgttatcctc aataccaaat ccatggattt acattatcaa
    61381 gggcaagtct tgaatttgac caagaacgaa ttccagattt tacgcgtgtt atttgagcat
    61441 gcaggcaaca tcgtagcacg tgacgacctg atgcgagaac tttggaacag tgactttttc
    61501 attgatgata ataccctctc tgtcaatgtg gctcgtttgc gtaaaaagtt ggaggagcag
    61561 ggattggtag gatttatcga gaccaagaaa ggaatagggt acggattgaa gcatgcttga
    61621 ttggaaacaa ttttttctag cctatctgcg ctcccgtagt cgtctttttg tctatctgct
    61681 ttctttggca tttctggtct tactctttca gtttttattt gccagtctag gaatttactt
    61741 cctctacttt ttcctcttgt gttgctttgt aaccatctta tttttcactt gggacatatt
    61801 ggtggaaatg caggtttatc gccaggaact tctctatgga gagagggaag ccaagtctcc
    61861 tttggaaata gctttagcag aaaaattaga agcgcgtgag atggaactct atcagcagag
    61921 gtcaaaagca gaaagaaaac tgacggattt gctggattac tataccttgt gggtccatca
    61981 gataaagacc cccattgcag ccagtcaact cttagttgca gaagtggtcg accgccaact
    62041 gaagcagcag ctagaacagg aaattttcaa aatcgactcc tataccaacc tagttttaca
    62101 gtacctgcgt ttagaaagtt tccatgatga tttgctctta aagcaggttc aaattgagga
    62161 cttggtcaag gaaataattc gtaaatatgc tcttttcttt attcaaaaag gcttaaatgt
    62221 caatctacat gaccttgata aagaaatcgt gacggataaa aagtggctgc tagtggttat
    62281 tgagcaaatc atctcaaaca gtctcaagta caccaaggaa ggtggtctgg agatttatat
    62341 ggatgaccaa gagctttgta tcaaagatac gggaatcggg ataaaaaaca gtgatgtcct
    62401 ccgagtattt gaacgtggct tttcaggata caatggccgt ttgacccagc agtcctctgg
    62461 acttggcctt tatctatcta agaaaatttc tgaagaactg gggcaccaga ttcgtatcga
    62521 gtctgaggtc ggaaaaggaa cgacagtgcg gattcagttt gctcaagtga acttagtcct
    62581 tgagtaaaaa tagatgagaa aaagcctcca gattggaggc ttttatgcta gactcttatt
    62641 tctcaacgcg tgatttgttg gcgatatcag ctaggatagc ttgaacaaaa ttatcaactg
    62701 agacagtttg tgtttctttt tggccgtagc gacgaacgtt gactgtttcg tcttccattt
    62761 ctttgtctcc aacaattaat tggtaaggaa tcttgctggt ttgtgaagca cggatcttga
    62821 actgcatttt ttcattgcgc tcatctacat ctgcacggac accgcggtca cggagtttct
    62881 tggccacttc ccaagcgtag tccacgtgtt tttcgttaga tactgggatg agggttactt
    62941 ggtgtggtgc cagccatgtt gggaaggccc ccttgtagtt ctcaatcaag atagctgtga
    63001 agcgttccat agttgagata actccacggt ggatcatgac tggacggtga tcttcgccat
    63061 cagctccgat gtatttgagg tcgaagcgtt ctggcaacaa gaaatcaagt tggatagtag
    63121 aaagggtttc ttcttttcca agggcagttt taatctggat atccaatttt ggtccgtaga
    63181 aggctgcttc accttcggct tcaaagtagt ccacgcccat ttcatcaaga gctgcacgaa
    63241 gcatggtttg ggcattttcc cacatctcat cgttatcaaa gtacttatga gtatcttgag
    63301 ggtcacgaag agagaggcgg aagcggtagt cagtcaagtt gaagtcttca taaacatcga
    63361 taatcaactg aagggcacgt tggaattctt cttggatttg ttctggagta acgaataggt
    63421 gaccgtcgtt gagtgacatt tcacgtacac gttgaaggcc agtgagggca ccagattttt
    63481 cgtaacggtg catcataccg atttcagcga tacggattgg caattcacgg taagagtgaa
    63541 catggtgttt aaaaacttgg atgtggtgcg gacagttcat tggacgaagg acaaattctt
    63601 ccccgtcacc catgtccatg gttgggaaca tgtcttcttg gtaatgatcc cagtgaccag
    63661 aagtcttgta aagctcaaca gaagcaagtg gtggagtgta gacgtgttgg tagccagaag
    63721 ccaactcttt gtttacgatg tagcgttcca attcacgacg gatagtcgca ccatttggca
    63781 accagaatgg caaaccttgt cccacttctt gtgaaatcat aaagaggtca agctctttac
    63841 caagtttacg gtggtcacgt tccttagctt cttcacgcat ttgaaggtag tttttcaagt
    63901 ctttcttgtc aaaccaagct gtaccgtaga tacgttgcat catagcgttg tcgctgtttc
    63961 cacgccagta cgcaccagct acatggagaa ggtggaagat ttggatacga cctgttgatg
    64021 gaacgtgagg tccacggcag aggtctacat attcaccctg acgatagata gtcaaaccgc
    64081 cttcgtcttc tgagtgttct tcaatcaatt ccaacttgta agggtcattt ttgaagattt
    64141 cacgtgcctc gtctttagtc acttcttcac gaatagatgg gaagttttct ttgacgattt
    64201 tttgcatttc ttcttcgata cgaggaaggt cttcgttaga gatttgacca gctgtgttgt
    64261 cagtatcgta gtagaaacca tcttcgatgg ctggaccaac tcccaagtga atgtctggga
    64321 aaagacgacg agctgcttgg gcgaacaagt gagctgctga gtgacgcaag attggaaggg
    64381 catcttcgtg atcaggtgtc acaatttcga tgcttccatc ttcagtgata gcgcgagtag
    64441 tgtcgatgag tttgccgttg aatttaccag ccaaggcttt tttagctagg gaattgctga
    64501 tagattgggc aatttcaaaa gttgttacgc cagattcgaa ttcacgaaca gcgccatctg
    64561 ggaaagtaat gttaatcatg atgttctcct tttttattat ttcatagttt ctaagcattg
    64621 attttttatc agcagactac ttccgagtcc taacgttcaa ttgcttttct ttatcagaga
    64681 ggaagttttt catttccgtc agaatgtcta tatccaaacg ttgagaaagt tctaatagcc
    64741 accagatatt ttctgaaagt ttttgttcca gtgtgtaggg tgtttcatca tagtagcgtc
    64801 cttgctttgt catcaccagt cattggaaat ttccaatatc attagataaa gccaagaggt
    64861 cttcttctac cgtccacttg aaatcatgat gcttaacttc cagttcgtga taagcttgtc
    64921 ggattgccca actgcgctcc actaattctt gcaactccat aattagtatc ctaataaaaa
    64981 aatgcgacat cctcgaaagg acgtcgcaac gtggttccac cttcatttat gtacctcaaa
    65041 agagagggac acctctgatc ggctctaacg tggccaccgt tttatgtttt cataaaaaac
    65101 tcaagagtag tatcagttta gacttcctat gcgtttccag caaccacgca ctctctagta
    65161 gaaagggact aagtgacttg tctctatgga ttattatagc atgattgtga gatttttcaa
    65221 ggattttgtg aaagtttttt gtttttcatt ttttgtagaa tatgcttgat gctaatacca
    65281 gaatccatgc cgaccagagc aactgtttca tagattagca agtaaattag tataaactca
    65341 ccaaaggtta tgatagtaaa gtaaaagagc agtccgttac caactaacca tcaaagtgag
    65401 aaacggaaac ggtagctata gagtaacgat ataatcaaga ttaccagagg tgtaaagaag
    65461 agaagattgt ttatatagag ttccttgagt gtaagggggt cagaaacaac tagtaagaac
    65521 aactcataaa gtggccaata aaagaataat atgaccagat agtaggggag atgggaatag
    65581 aatctacgca tgataatcac ctcgttttaa aaaaacagac aacttagatc tcttgctatg
    65641 attattatag catgtttaaa acaagaaagt aaatttgttg acaaagaaga tttttctttt
    65701 cactagaatc atagttagtt ttcttggtag aaatattttg ataataatta agcaagacta
    65761 ttgacattaa ttattaagag tgtcacaatt gttgtaacta aaataattac aacaagagag
    65821 gtataaaaaa tgaaactagc agttattgca gcaaatggac aagcggggaa agcaattgtt
    65881 gaagaagcag tcaaacgagg acatgaagta acggctattg ttcgttctga aaacaaaagt
    65941 caagctgagt ctattattaa aaaagattta tttgagttga caaaagatga tcttactgga
    66001 tttgatgctg ttatttcagc gtttggtgct tatacaccag atacgctacc gctccacagc
    66061 aaatcaatcg aactatttaa tcagcttctt gctggaacac agacacgttt tctagttgta
    66121 gggggagcag gaagtcttta tatagatgaa acaaaaacga cacgactttt agatacgtct
    66181 gattttcctg aagaatttaa gtcactagca aaagctcaag cggatgaatt ggatcttctt
    66241 cgtacaaaaa ataatctcaa ctggactttt gtcagtcctg ctgtagattt tattcccgat
    66301 ggtgaaaaaa caggaaacta cattctagca ggagaaattt ttactactaa tggaaaagga
    66361 ataagccaga ttagttatgc agattatgct attggattgg tagatgaact tgaaaaaggt
    66421 catcatataa aagaacgtat ctctttactt gaaaaataat aactatgaga gtattaatgt
    66481 ttgacagaaa atttaaatct tggtaaaata aggattgtcg taaagacaaa taacttcttc
    66541 ttggttacag gcatgccaac ctgtcactcg gatgaagcca aataaaaagg agaaacatca
    66601 tggcaatctc aaaagagaaa aaaaatgaaa tcattgcaca atatgcacgt cacgaaggtg
    66661 atacaggttc agtagaggtt caagttgctg tccttacttg ggaaatcaat caccttaacg
    66721 aacacatcaa acaacataaa aaagaccacg ctacttaccg tggattgatg aaaaaaatcg
    66781 gtcgccgtcg taacttgctt gcatacttgc gtaaaaacga cgttaaccgt taccgtgagt
    66841 tgatcaactc tctaggactt cgtcgctaat tcaagataca aatgctgtca aaagcacaaa
    66901 gcaaaaatag gaaaattgac gaagaaactt cagtttctag gagattttat cttttttgcc
    66961 aagtgcttag gccgtgttca attgagcata tcttgataat aaagctactc taaattgggt
    67021 agcttttttg cgttgtcacc ttacctcgat atactcaagt ataatctttg gttacggttc
    67081 ctagcactgt aaggtaaaat aaaccagctt ttctcccttc ggggagattt ttttgtttca
    67141 ctgaaagttt cgtacgatct tcgcctcgtc gcctagtcta taaacgattt atctagcaag
    67201 aatcatgatg ctaagggcgt caaaaatccg tatgaaaata gggaaatgac acagtgttcg
    67261 atgagcacaa ggagtttcat ctttttcact aggattttag cccgggctca aatcagctct
    67321 ctgacttcag agggcttttt tattgaggtt ttatcggtaa caattttgga gactacaaaa
    67381 atctcaaacg gtatcagcta attacaccat aaaggtgcgc agttactcgg cttttcaagc
    67441 cgagtagctg tatgcaagcc ccctagaaga gcccactctt tacaaagtaa agtatagtat
    67501 gttatacttt acatggaagt agtcactgaa ttccagttag aaattacttt gtaactacgt
    67561 tttgaggagg agtaaaatgc tttcctacgt tcgacattac ccactagcga tagctaaatt
    67621 aatgtgtctg tgctctccta aaatctgctg atttattact gactaataca ggagtttttt
    67681 ttatgggaca gacaatcata tctgctattg gtgtttatat ttccaccagt atcgattatt
    67741 taattatttt aattatttta tttgcacagc tatcacagaa taaacagaaa tggcatattt
    67801 atgcggggca atatctaggc acaggcttac ttgtaggggc gagtttagtt gctgcttatg
    67861 tcgttaattt cgtgcctgaa gaatggatgg ttggattgct tggtttaatc cctatctatt
    67921 tagggattcg ctttgcaatt gttggagaag atgcggaaga agaagaggaa gaaattattg
    67981 aaagattaga acaaagcaag gcaaatcaac tgttttggac agttacattg ctgacaattg
    68041 cgtctggcgg agataattta ggtatctata taccttattt tgcttcgtta gattggtcac
    68101 agaccctcgt ggccttgctt gtgtttgtaa tcggcataat tatcttttgc gagattagtc
    68161 gggtgttatc ctctattccg ttaatattcg agacaattga aaaatacgag cgaatcattg
    68221 tgcccttagt attcattcta cttggactat acatcatgta tgaaaatggc acgatagaga
    68281 cttttctgat cgtgtagatt tttttgtttc actaggattt tagtccgagc tcaaatcagc
    68341 tctctgattt tcagagggct ttttcattga gtataaatgg acaatcttaa agttactcta
    68401 ttgtagagtg gcttttgatt tgattaggag attcttataa atatagtaaa atgaaataag
    68461 aataggacaa atcgatcagg acagtcaaat cgatttctaa aaatgtttta gaagtagagg
    68521 tgtactattc tagttccaat ctactatata aatgaaaacc ttagctgttt cgccaaggtt
    68581 catttcttct atgcaagttc ttctcttttc ttatctgggt tccagatgaa gcttgcgata
    68641 aagctaaaga tgatggttag gatagcgagg ataatagcaa ggatgagggc agggatgcgg
    68701 ataaaccacc agagtggatt tggtttttta tcattgtgcc attgtttcgt ttcttcgtcc
    68761 agacgttgga attctgtttg aatacgattg gcgactgttt caatgccttc atcattcatt
    68821 ttcttgatat ctgagatatc gattggattt ccaaagttca tatcgacacg ttcacggcta
    68881 atcaagccct tcaaagtcat gggaccggtg taggtaaccg gcatgatacg gaccttggcc
    68941 attttggcaa tcagtgctgc gccccccttg acatcgtttg agtggcggct accacttgga
    69001 aacatgatga gagagcggtc actttttttg agaacgttga taggatattt gatggctgag
    69061 gcgctgggat tttcacggtc gatgggaaag gcgccacaca tacgaatcca ccaaccaaag
    69121 atacggttgg taaagagttc tttttttgcc ataaagatga actgttttgg cttggtcgca
    69181 aaggccatat aaacaggatc ccaccaggta cggtgaggcg caactaaaat ataattttca
    69241 tcttgattag gaattttatt agtattatga tagtgagcat tgccattgat ggaccataag
    69301 agcaatacaa ctaatccacg caaataagta taaaacatgc gatctccttc gattgttttc
    69361 ttgttattat tataccttat caaaggaggg ctggcaaact tttcccttga ctagatgcat
    69421 atttgggatg aaattagaat tctgttaaaa aaaatgatat aatagaattt atggataaaa
    69481 ataagattat gggattaacc caaagagaag tcaaggaaag acaggctgag ggtttggtca
    69541 atgactttac cgcatcagcc agtaccagca cttggcaaat cgttaaacga aatgtcttta
    69601 ccctttttaa cgctttgaac tttgccattg ctttggctct tgcctttgtg caggcttgga
    69661 gcaatctggt cttctttgct gttatctgct ttaacgcttt ttctgggatt gtgaccgagc
    69721 tacgagccaa acacatggtg gacaagctca atctcatgac caaggaaaag gtcaaaacca
    69781 tccgtgatgg tcaggaagtt gctcttaatc ctgaagaatt agtgctagga gatgtcattc
    69841 gtttgtctgc aggagagcag attcctagtg atgccttggt tttggaaggc tttgcggaag
    69901 tcaatgaagc catgttaacg ggagaaagtg atttggtgca aaaggaagtt gacggcttac
    69961 ttttgtcagg aagtttccta gccagtgggt cagttttatc tcaagttcac catgtcggtg
    70021 cagacaacta tgctgccaaa ctcatgcttg aggctaagac cgttaaaccc atcaactccc
    70081 gtatcatgaa atcgctggac aagttggctg gttttactgg gaagattatc attccctttg
    70141 gtctggctct cttgctggaa gccttgcttt taaaaggcct gcctctcaag tcatccgttg
    70201 taaactcgtc gacagctctt ttgggaatgt tgcctaaggg aattgccctt ttgaccatta
    70261 cttcgctctt gactgcagtg attaagttgg gcttgaaaaa ggtcttggtg caggagatgt
    70321 actctgttga gaccttggcg cgcgtggata tgctctgtct ggacaagacg ggcaccatca
    70381 cccaaggaaa gatgcaggtg gaggctgttc ttccactgac ggaaacttac ggtgaagagg
    70441 ctattgccag catcttgact agctacatgg cccatagtga ggataagaat ccaactgccc
    70501 aagccattcg ccagcgtttt gtgggagatg ttgcttatcc tatgatttcc aatcttccct
    70561 tctcgagcga ccgcaagtgg ggggctatgg agttagaagg cttggggaca gttttcttag
    70621 gggcacctga gatgttgctg gattctgaag tcccagaagc cagggaggcc ttggagagag
    70681 gatcacgtgt cttggtctta gctctcagtc aggagaaatt agaccatcac aaaccacaga
    70741 aaccatctga tattcaggct ctagccttgc tggaaatctt ggaccccatt cgagagggag
    70801 cagcagagac gctggactat ctccgttctc aggaggtggg actcaagatt atctctggtg
    70861 acaatccagt tacggtgtcc agcattgccc agaaggctgg ttttgcggac tatcacagct
    70921 atgtagattg ctcaaaaatc accgatgagg aattgatggc catggcggag gagacagcta
    70981 ttttcggacg tgtttcccct catcaaaaga aactcatcat ccaaacgttg aaaaaagcgg
    71041 gtcatacaac ggctatgaca ggggacgggg ttaatgatat cttggccctt cgtgaggcgg
    71101 attgttctat cgtgatggcg gagggggatc cagcaacccg tcagattgcc aatctggttc
    71161 tcttgaactc agactttaat gatgttcctg agattctctt cgagggtcgt cgcgtggtca
    71221 ataacattgc ccacatcgcc ccgattttct tgataaagac catctattcc ttcctgttag
    71281 cagtcatctg tattgccagt gctttactag gtcggtcaga gtggattttg attttcccct
    71341 tcattccgat ccagattacc atgattgacc agtttgtgga aggtttccca ccattcgttc
    71401 tgacttttga gcgaaatatc aaacctgtcg agccaaactt cctcagaaga tccatgcttc
    71461 gtgccctacc aagtgccctc atggtcgtgt ttggcgttct ttttgtgaaa atctttggaa
    71521 cgagtcaagg ttggtctgag ttagaaatct caactctcct ctattatctc ttggggtcaa
    71581 ttggtttctt atccgtattt agagcctgca tgccattcac tctatggcga gtcctattga
    71641 ttgtctggtc agtaggaggc ttcctagcca cagctctctt ctcaagaatt caaaaactgc
    71701 ttgaaattgc aaccttaaca ggacaaacat tacctgttta tggtgtcatg atgttggtct
    71761 ttaccgtgat tttcatcctg accagtcgtt accaagcgaa aaaataaaga aagactgcaa
    71821 tctgtggatt gcagtttttt taggtacaag attgccagcc gaaatgtggt ataataagag
    71881 gtaatagagt tttggaaagt gagagaagat gatttcaaag agattagaat tggtagcttc
    71941 ctttgtgtca cagggggcta ttttactaga tgtgggaagt gaccatgctt atctgcctat
    72001 cgagttggtt gagagaggcc aaatcaaaag cgctattgca ggtgaggtgg tggaaggtcc
    72061 ctatcagtct gcggttaaaa atgttgaggc tcacggccta aaggagaaaa tccaagtccg
    72121 tttagccaat ggcttggcag cttttgaaga gactgaccaa gtgtctgtca ttaccattgc
    72181 tggcatgggt ggttgtttga ttgctaggat tttagaagaa ggtttgggga agttagctaa
    72241 tgtagagcgt ttgatcctcc agcccaataa tcgtgaagac gacttgcgta tctggctaca
    72301 gaatcatgga ttccagattg tagcagaaag catcttagaa gaagctggca agttttacga
    72361 gattttggtg gtggaagcag gacaaatgaa gctatcagcc agtgatgttc gctttggtcc
    72421 cttcttgtcc aaagaagtca gtccagtatt tgtccaaaaa tggcaaaaag aagctgagaa
    72481 gctagagttt gccctcggac aaatcccaga aaaaaatctg gaggaacgtc aagttctagt
    72541 agataagatt caagctatca aggaggtgct ccatgttagc aagtgaagtg atccaagctt
    72601 atgaagcctt ttgccctcag gaattttcta tggagggaga cagccgtggt ctgcaaattg
    72661 gcactttaga caagggtatc caaagggtca tggttgccct cgatattcgt gaagagacgg
    72721 tggcagaggc cattgaaaag ggtgtggact tgattatcgt caagcacgcg cctatctttc
    72781 gtcctatcaa ggacttgctt gccagccgtc cgcaaaatca gatttacatc gacctgatta
    72841 agcatgacat cgcagtttat gtcagccata ccaatattga tatcgttgaa aatgggctca
    72901 atgactggtt ttgtcagatg ctaggaatcg aggagacgac ttatctgcag gaaacaggtc
    72961 cagaacgtgg aattggacgt attgggaata ttcagcctca gacattttgg gaattggccc
    73021 aacaggtcaa gcaagtcttt gacctagata gccttcgaat ggtgcattat caagagaatg
    73081 atttgcagaa gcctatttca agagtagcaa tttgtggtgg aagcgggcag tctttctata
    73141 aggatgcttt ggcaaagggg gcagatgtct atatcactgg tgatatctac taccatactg
    73201 ctcaggatat gctgtctgat ggcttgttag cattggatcc aggtcactat atcgaagtgc
    73261 tttttgtgga aaaaatcgca gcactcctta ctcaatggaa agagaaaaaa ggctgggaac
    73321 tagagatttt acctagtcaa gcatcgacca atcctttccg tcatatctag ttagaaagtg
    73381 aagacaatga aaaaagttgc cattattgga gcaggaattg tgggagcaac agctgcctac
    73441 tacctctcga gagaaagtga cctagaggtg accgtttttg accatgagca aggtcaagcc
    73501 accaaggccg cagcaggaat tatcagtcct tggttttcca aacgccgtaa taaagcctgg
    73561 tacaagatgg cgcgcttggg ggctgacttt tatgtggatt tattagctga tttagagaaa
    73621 tcaggacaaa aaatcgactt ttaccagcgt tcgggagtct ttctcttgaa aaaggatgaa
    73681 tccaagttgg aagaacttta tcaactggcc ctccagcgca gagaagaatc tcccttgata
    73741 gggcaattag ccattctgga ccaagcttca gctaatgaat tattccctgg tttgcaggga
    73801 tttgaccgcc tgctctatgc ttctggtgga gcgagagtag atggccaact cttggtaact
    73861 cgtctgctag aagccagtca tgtcaagctg gtcaaagaaa aagtgactct gacactctta
    73921 tcatcaggct accagattgg cgaagaggtg tttgatcagg ttattttggc aacgggagct
    73981 tggttggggg acatgttaga gcctttaggt tatgaagtgg atgtccgtcc tcaaaaagga
    74041 caactacgag attatcagct tgcccaagac atggaagatt accctgttgt catgccagaa
    74101 ggggagtggg atttgattcc ctttgcaggt gggaaattat ccttgggcgc tacccatgaa
    74161 aatgacatgg gatttgattt gacggtagat gaacccttgc tccaacaaat ggaggaggcg
    74221 gccttgcctc attacccagt tttagctaga gcgacttcaa gggctgagcg tgtgggaatc
    74281 cgtgcctata ccagtgattt ctctcccttc tttgggcagg tgccagaatt ggcaggtgtc
    74341 tatgtagcca gtggactagg ttcatcaggc ctcacaactg gtcctatcat tggttaccat
    74401 ctagcccaac tgatccaaga caaggagttg accttggacc ctctaaatta tccaattgaa
    74461 aactatgtca aacgagtaaa aagcgaataa tactcaatga aaatcaaaga acaaactagg
    74521 aaactagccg cgggttactc aaagcactgc tttgaggttg tgtatagaac tgacgaagtc
    74581 agtaaccata cccatggcaa ggcgacgttg acgtggtttg aattggattt tcgaagagta
    74641 taagcatttt actgaaattt tatcaggtag tttaggatgg caaatgacat tccctgtcaa
    74701 aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa aaaagatgca agaaaagatt
    74761 ttggtaactg gtggtgccgg ttttattgga acccacactg ttattgaatt gatccaagca
    74821 ggccatcaag ttgttgtggt ggataatctt gtcaatagca atcgtaagag tttagaagtt
    74881 gttgaaagaa tcacaggagt tgagattcct ttctatgagg cagatattcg tgacacagtt
    74941 accctcagag atattttcaa gcaggaagaa ccgactggtg tcattcactt tgctggtttg
    75001 aaggctgttg gcgaatcaac acgtatccct cttgcctact atgacaacaa tatcgctgga
    75061 actgtcagcc ttttgaaagc catggaagaa aacaactgta aaaacatcat cttcagttct
    75121 tctgcgacag tttacgggga tccgcacaca gtgcccatct tggaagattt cccactttca
    75181 gtgaccaacc catacggtcg taccaagctc atgctagagg aaattttgac cgatatttac
    75241 aaagcagact cagaatggaa tgttgtcttg cttcgttact ttaacccaat cggagcccat
    75301 gagagtggtg atttgggaga aaatccaaac ggtattccaa acaatctctt gccatatgtg
    75361 actcaagtag ccgttggaaa attagagcaa gtgcaagtgt ttggagacga ttacgatacg
    75421 gaagatggaa caggtgttcg tgactatatc cacgttgtcg atttggctaa gggtcacgtt
    75481 gcagctttga aaaaaatcca aaaaggttca ggactaaacg tttataacct tggaactggt
    75541 aaaggttact cagttcttga aattatccaa aacatggaaa aagcggtggg acgtcctatt
    75601 ccttaccgca tcgtagaacg tcgcccaggt gatatcgctg cctgctactc agacccagca
    75661 aaagctaaag cagaactcgg ttgggaagca gaactcgaca tcacccaaat gtgtgaagac
    75721 gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag actaagatga tgatttcaat
    75781 catcgtccct tgtttaaacg aagaggaagt acttcctctt ttttatcagg ctctggaagc
    75841 tttacttcca gatttggaaa cagaaatcga gtatgtcttt gtcgatgatg gatcaagtga
    75901 tgggaccttg gaactcttaa aggcctatcg ggagcaaaat ccggcagtcc attatatttc
    75961 tttctctcga aattttggca aagaagcagc cctttatgca ggcttgcaat atgcgacagg
    76021 agatttggtg gtggtgatgg atgcagacct ccaagatcct cctagtatgt tgtttgagat
    76081 gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt gggacacgga gaactagtcg
    76141 ggagggagaa cccttctttc gcagtttctg tgctgttctc ttttatcgcc tcatgcaaaa
    76201 aatcagccca gtagctctgc cgtcgggtgt ccgtgacttt cgtatgatga gaaggtctgt
    76261 ggtcgatgcc attttaagct tgactgagtc caatcgtttt tctaagggac tctttgcctg
    76321 ggtcggcttt aaaacccact atctggacta tccaaatgtc gaaaggcagg ctggcaagac
    76381 cagttggagt tttaggcaac tcttttttta ctccattgaa gggattgtta atttttcaga
    76441 tttccctttg actatagcct ttgtagctgg tctcctatct tgttttcttt ctctgctgat
    76501 gacctttttt gttgtggttc ggaccctcat tttgggcaat ccgacatctg gttggacctc
    76561 tctgatggct gttattctct ttcttggagg cattcaactc ttgaccattg ggattctcgg
    76621 taagtatatc agtaagattt atttagagac taaaaaaaga ccactttatc ttatcaaaga
    76681 aaaaagtgac cttcctgatt ttacagaaaa aataaagtga aaagactata attttacatg
    76741 gaaatgtgct aaactagagg gagtggatta tcgccattga tttaggcttc ctggtttcca
    76801 atcagggcgc gagttgggca atttttaaca gcctctaaga catcccgact aggagaaatt
    76861 tctttttcca gttggtcagg gtcatcgtaa aaacgcacga ttccattatc gtggtaatca
    76921 aataaatcag aataagtttg gcaaagtcca caggcgatac atcgttcagg tataagtgtg
    76981 attttcatgt tcatatttat attgtaataa gaaaagtaaa aaaaaacaag gagtaaggta
    77041 tggcaaaaga accgtggcaa gaagatattt atgatcaaga agaatcaaga gcagggcgtc
    77101 ggcatcgaaa ccacggaggg gctgatagga tggctaatcg tattttgacg atcctagcta
    77161 gtattttctt tgtaattgtg gtggtgatgg tcatcgttct catctatcta tcatcggggg
    77221 ggagtaatcg cacagcagcc ttaaaagact ttcatgattc tgatgcaagt gtagtacaaa
    77281 tctcatcttc aagcagttct cagcctgagc agagttcaga gccagaatct acttctagta
    77341 gttcagaaga agctgctaat cctgaaggaa cgattaaagt tctcgcagga gaaggggaag
    77401 cagctattgc cgctcgtgca ggaatctcca ttgctcagtt agaggccttg aatcctgggc
    77461 acatggctac aggatcttgg tttgctaatc caggtgatgt tataaaaata aaataggagc
    77521 cgatatgaaa acaattcaaa ttgctattga tggtcctgct tccagcggta agagtacggt
    77581 cgcaaagatt attgctaagg attttggatt cacctacctt gatacaggag ctatgtatcg
    77641 tgcagcgacc tatatggctc ttaagaacca attaggagtt gaagaagtcg aagcccttct
    77701 agccttgttg gaccagcatc caatcagctt tggacgttca gaaactggag accagcttgt
    77761 ttttgtagga gatgtggata ttacccatcc tatccgtgaa aatgaagtga ccaatcatgt
    77821 ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg gtttctctcc aacaagaaat
    77881 tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt ggaactgttg tattgccaca
    77941 agcagaattg aaaattttcc tagtagcttc tgttgatgag agagcagagc gtcgttacaa
    78001 ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc ctaaaaaagg aaattgctgc
    78061 gcgtgactac aaggatagtc atcgtgagac ttctcctctc aaacaagcag aggatgctgt
    78121 ctaccttgat acaactggtt tgaacattca agaagtagtt gaaaaaatca aagcagaagc
    78181 tgaaaaaaga atgtaaatgt agaaaagccg atagattgat atcggttttt ttctaaattt
    78241 gtcaaaatgc tgattttagg gtataatagt tgctgttcga gaaattttga ttttcaaaga
    78301 atagtgaatg atgataagga gaaaccatga acaatttacc aaattgtcca aaatgtaact
    78361 cagagtatgt ctacgaagac ggtgccctac tggtttgccc agagtgtgct catgagtgga
    78421 atcctgctga agttgcagaa gtagaagaag gtcttgtcgc tatcgatgcc aacggaaata
    78481 aattggctga tggtgatata gtaactctca tcaaggactt gaaagtaaaa ggtgcgccaa
    78541 aagatttgaa acaagggacg cgcgtgaaaa atatccgcat cgtagaaggc gaccacaata
    78601 tcgactgtaa gattgatggt tttggtgcca tgaaacttaa atcagagttt gtgaggaaga
    78661 tttaagcatg tcaaaacact ataaacttgt attttatagc cgtatcttct tgtttctagc
    78721 ggcttttacg ggagtttatc ttgaaattac taggcatggt ggttttggga tgcttctcta
    78781 ttacacggtt ctgtccaacc tcttggtaac tatttttacc ctttatcttc taaaggttat
    78841 gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg cgcttaaaag gtggggtcac
    78901 catgagtatc atgattacct gtgtgattta ccatttcctc ttggcgccca ttgcgactaa
    78961 tttctatacc ctagaaaatt tcctttgcca ctatatcgtt cccatctggt ttttagcgga
    79021 taccctcttt tttgacaaac agggtcaata caagatttgg gatccagcag tgtggaccat
    79081 tttacccttt ctgtatatga tgtttgctct ttttaatggc ttggttctaa aactcaatat
    79141 tccaaatgcc aaggataatc ctttccctta cttctttttg aatgtgaaca agggttggaa
    79201 tgttgtgttt aagtggtgtc tgattatctt tgttgcctat atggtagcag gatttatttt
    79261 ctactttatc aagcaaatca agagaaagtc atcctaatac tcttcgaaaa tctcttcaaa
    79321 ccacgtcagt ttccatctgc aacctcaaaa cactgttttg aacaacctgc ggctagcttc
    79381 ctagtttgct ctttgatttt cattgagtat aagatacaag ggattcattt tcgaatttaa
    79441 gaaggagtct acaaaccaat gaggcttctt cttttcttgc ttatttgata actatcaaaa
    79501 aagtagaaga ttaagagaaa tatagaaaga gatttcatga aacaattttt agaacgggcc
    79561 agcattttgg ctctctccct cgttttgatt acctcctttt ccatttcgag tgccctacca
    79621 gccatgtttg actattatca gggttattct aaggaacaaa ttgagctctt ggtgagcttg
    79681 ccttcctttg gaatcatgat gatgttactg ctaaatggtt tcttagaaaa aatatttcct
    79741 gagcgcttac agattagttt gggcttgctg attttatcat tgagcggtac agctcccttc
    79801 tggtaccaag cctatccctt tgtctttgga acacggcttc tctttggttt gggtcttggg
    79861 atgatcaatg ccaaggccat ttctattatc agtgaacgct atcaaggaaa aaggcgaatt
    79921 cagatgttag ggctacgcgc ttctgcagag gtcgttggag cttctctcat taccttggcc
    79981 gtcggtcagt tgttggcctt tggttggaca gctatctttc tagcctatag tgctggattt
    80041 ttggtgctgc ccctttatct gctctttgtc ccttatggaa aatcaaagaa agaagtcaag
    80101 aaaagagcga agaaagcaag tcgtttaact cgagaaatga aaggcttgat ttttacctta
    80161 gctatcgaag cggcagttgt agtttgtacc aatacagcta ttaccatccg tattccaagt
    80221 ttgatggtgg aaagaggatt gggggatgcc cagttatcta gttttgttct tagtatcatg
    80281 cagttgatcg ggattgtggc tggggtgagt ttttctttct tgatttctat ctttaaagag
    80341 aaactgctcc tctggtctgg tattaccttt ggcttggggc aaatcgtgat tgccttgtct
    80401 tcatccttgt gggtggtagt agcaggaagt gttctggctg gatttgccta tagtgtagtc
    80461 ttgacgacgg tctttcaact tgtctctgaa cgaattccag ctaaactcct caatcaagca
    80521 acttcatttg ctgtattagg ctgtagtttc ggagccttta cgaccccatt tgttctaggt
    80581 gcaattggct tactaactca caatgggatg ttggtcttta gtatcttagg aggttggttg
    80641 attgtaatct ctatctttgt catgtaccta cttcagaaga gagcttagga ttgattccta
    80701 agtttttctt ttgatactca atgaaaatca aagagcgtag ttgattgagt ttggaatagt
    80761 acgctgtagc tgctaaaata tttctagaaa ttaatttgac tttcctaata gaattgttca
    80821 tatcttattt caatctacta tagaaagcta gccgcaggtt gctcaaaata gtgttttgag
    80881 gttgcagatg gaaactgacg tagtttgaag agattttcga agagtatgag atttttatac
    80941 ccatacaata tttgttttag gtccttgttt acagactaat ttcttgataa aatagaggtt
    81001 atgacgagat ataaagcaac tatttcctat gatggttatg cctttgctgg ctttcagcgc
    81061 cagcctcatg cgcgtagcgt tcaggaagaa attgaaaaaa ccttgaccag attaaataaa
    81121 gggcaaacca ttactgttca cggtgctggt aggacagata gtggggttca tgccctggga
    81181 caggtcattc attttgacct gccttatcag atggatgagg agaaactccg ttttgccttg
    81241 gatacccagt ctcctgaaga tattgatgtg atttcgattg agcttgtggc agatgatttt
    81301 cattgccgtt atgccaaaca tagcaagacc tatgagttta ttgtggatag aggacgtccc
    81361 aaaaatccta tgcgccgtca ctatgccacc cactttccct acccactcga tgtggaacga
    81421 atgcagattg caatcaaaaa gctagaggga acccatgatt ttaccggttt tacagcctct
    81481 gggactagtg tagaggataa ggttcgcacc atcacagaag ctagtttaat agtcgatgag
    81541 acaggacaat ttttgacctt taccttttca ggaaatggtt tcttgtataa acagattcgc
    81601 aatatggtgg ggactcttct caaaatcggt aacaaccgca tgccagtaga gcagattgct
    81661 ctcatcttgg agaagaagga caggcaactt gcaggtccca ctgcagcacc aaatggtttg
    81721 tatttaaagg agattcgtta tgaagaataa tcgtatttta gcactttctg gaaatgatat
    81781 ttttagtggt ggtggactgt cagctgattt ggctacctat accttgaacg gcttgcatgg
    81841 gtttgtagca gtgacttgtt tgacagcctt gacagaaaaa ggatttgaag tctttccaac
    81901 tgatgatacc atttttcaac atgaattaga tagcttgcgt gatgtggaat ttgggggaat
    81961 taagattggt cttctcccta ctgtcagtgt ggctgagaag gccttggact ttatcaaaca
    82021 acgcccagga gtacctgtgg tgttggatcc tgtcttggtc tgcaaggaaa cgcatgatgt
    82081 agctgtcagt gagctctgcc aagagttgat tcgcttcttc ccttatgtca gtgtgattac
    82141 gcctaatctc ccagaagcag aattattatc cggtcaggaa attaaaacct tggaagacat
    82201 gaaaactgca gcgcagaaat tgcatgattt aggagcgcca gcagtcatta tcaagggagg
    82261 caatcgtctt agtcaggaca aggctgtgga tgtcttttat gatggacaga cctttactat
    82321 cctagaaaat ccagttatcc aaggccaaaa tgctggtgca ggttgtacct ttgcctctag
    82381 cattgccagt cacctggtta aaggtgataa acttttgcca gcagtagaaa gctctaaggc
    82441 tttcgtttat cgtgctattg cacaagcaga tcagtatgga gtaagacaat atgaagcaaa
    82501 caaaaacaac taaaatcgcc cttgtatccc tattaaccgc cctttctgtg gttctaggtt
    82561 atttcttaaa attcccaaca cctacaggaa ttctaactct tttagatgct ggtgtcttct
    82621 ttgcggcctt ttactttggt agtcgtgaag gagcggtagt cggaggacta gcaagtttct
    82681 tgattgacct cttatcaggc taccctcagt ggatgttctt tagcttggtc aaccatggct
    82741 tgcagggatt tttcgcagga tttaaaggaa aaagtcagtg gttaggcctt attttagcaa
    82801 ctattgccat ggtaggaggc tacgccttgg gttctacttt gatgaatggc tgggcagcag
    82861 ccctcccaga aattctaccg aattttatgc aaaatatggt agggatgatt gtaggattta
    82921 ttcttagtca aagtatcaag aagattaagt aatactcttc gaaaatctct tcaaaccacg
    82981 tcagcttcca tctgcaacct caaaacactg ttttgagcag ccagaggcta gctttctagt
    83041 ttgcactttg attttcattg agtataaaga ggttgagtaa aaagtctttc aaataagaaa
    83101 aacgcattat atcaagtctt gactgaactg caccccaaaa gttagacaga aaaaatctaa
    83161 cttttggggt gtttttatta tgaaa
//
LOCUS       DBEJZV010000005        80682 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.05, whole genome shotgun sequence.
ACCESSION   DBEJZV010000005 DBEJZV010000000
VERSION     DBEJZV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 80682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80682
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.05"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(190..1938)
                     /locus_tag="ACL3S0_000397"
     CDS             complement(190..1938)
                     /locus_tag="ACL3S0_000397"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311375.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPIFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTHLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1940..3664)
                     /locus_tag="ACL3S0_000398"
     CDS             complement(1940..3664)
                     /locus_tag="ACL3S0_000398"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311376.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNRSYISAKRIKEVFVEAPEDIHSELEQKQVTSDRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIASVPQKVELFKGTIRSNLTLGFNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3724..4662)
                     /gene="msrB"
                     /locus_tag="ACL3S0_000399"
     CDS             complement(3724..4662)
                     /gene="msrB"
                     /locus_tag="ACL3S0_000399"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR1311377.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4729..4881)
                     /locus_tag="ACL3S0_000400"
     CDS             complement(4729..4881)
                     /locus_tag="ACL3S0_000400"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311378.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEVSSRHCFEVADRTDEVS
                     NIYTVR"
     gene            complement(4957..5826)
                     /gene="thrB"
                     /locus_tag="ACL3S0_000401"
     CDS             complement(4957..5826)
                     /gene="thrB"
                     /locus_tag="ACL3S0_000401"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGR1311379.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(5828..7114)
                     /locus_tag="ACL3S0_000402"
     CDS             complement(5828..7114)
                     /locus_tag="ACL3S0_000402"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGR1311380.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7265..8002)
                     /gene="mecA"
                     /locus_tag="ACL3S0_000403"
     CDS             complement(7265..8002)
                     /gene="mecA"
                     /locus_tag="ACL3S0_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGR1311381.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8202..9236)
                     /locus_tag="ACL3S0_000404"
     CDS             complement(8202..9236)
                     /locus_tag="ACL3S0_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR1311382.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9265..10698)
                     /locus_tag="ACL3S0_000405"
     CDS             complement(9265..10698)
                     /locus_tag="ACL3S0_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGR1311383.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGILFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(10714..11700)
                     /locus_tag="ACL3S0_000406"
     CDS             complement(10714..11700)
                     /locus_tag="ACL3S0_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR1311384.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNSIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11702..12805)
                     /locus_tag="ACL3S0_000407"
     CDS             complement(11702..12805)
                     /locus_tag="ACL3S0_000407"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR1311385.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLYQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12795..13640)
                     /locus_tag="ACL3S0_000408"
     CDS             complement(12795..13640)
                     /locus_tag="ACL3S0_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR1311386.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSCILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13919..15193)
                     /gene="psr"
                     /locus_tag="ACL3S0_000409"
     CDS             complement(13919..15193)
                     /gene="psr"
                     /locus_tag="ACL3S0_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGR1311387.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15190..16038)
                     /gene="pheA"
                     /locus_tag="ACL3S0_000410"
     CDS             complement(15190..16038)
                     /gene="pheA"
                     /locus_tag="ACL3S0_000410"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR1311388.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(16035..16511)
                     /locus_tag="ACL3S0_000411"
     CDS             complement(16035..16511)
                     /locus_tag="ACL3S0_000411"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGR1311389.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16504..17787)
                     /gene="aroA"
                     /locus_tag="ACL3S0_000412"
     CDS             complement(16504..17787)
                     /gene="aroA"
                     /locus_tag="ACL3S0_000412"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGR1311390.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQDVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVAGGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17879..18217)
                     /locus_tag="ACL3S0_000413"
     CDS             complement(17879..18217)
                     /locus_tag="ACL3S0_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGR1311391.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18228..19331)
                     /locus_tag="ACL3S0_000414"
     CDS             complement(18228..19331)
                     /locus_tag="ACL3S0_000414"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGR1311392.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19341..20507)
                     /gene="aroC"
                     /locus_tag="ACL3S0_000415"
     CDS             complement(19341..20507)
                     /gene="aroC"
                     /locus_tag="ACL3S0_000415"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGR1311393.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20517..21584)
                     /gene="aroB"
                     /locus_tag="ACL3S0_000416"
     CDS             complement(20517..21584)
                     /gene="aroB"
                     /locus_tag="ACL3S0_000416"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGR1311394.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(21603..22457)
                     /locus_tag="ACL3S0_000417"
     CDS             complement(21603..22457)
                     /locus_tag="ACL3S0_000417"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGR1311395.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATDTNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(22447..23124)
                     /gene="aroD"
                     /locus_tag="ACL3S0_000418"
     CDS             complement(22447..23124)
                     /gene="aroD"
                     /locus_tag="ACL3S0_000418"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGR1311396.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVIGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23121..24284)
                     /locus_tag="ACL3S0_000419"
     CDS             complement(23121..24284)
                     /locus_tag="ACL3S0_000419"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGR1311397.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVTFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLTMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24969..26603)
                     /locus_tag="ACL3S0_000420"
     CDS             complement(24969..26603)
                     /locus_tag="ACL3S0_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311398.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFVVAILLVIAFSTSLTAFYNVFYESK
                     DLASYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTTAFRKYQSIFSNVMIGIGVLIPLIFVFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPILTLLGLSLYLGLPIISMIYLIMAWILASVIL
                     SCHHYFKDVKNLSINWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(26584..27333)
                     /locus_tag="ACL3S0_000421"
     CDS             complement(26584..27333)
                     /locus_tag="ACL3S0_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311399.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQDLSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSSSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDLDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRRDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            27512..28966
                     /locus_tag="ACL3S0_000422"
     CDS             27512..28966
                     /locus_tag="ACL3S0_000422"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGR1311400.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPIADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(29056..31674)
                     /gene="alaS"
                     /locus_tag="ACL3S0_000423"
     CDS             complement(29056..31674)
                     /gene="alaS"
                     /locus_tag="ACL3S0_000423"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGR1311401.1"
                     /translation="MKQLSSAQVRQMWLDFWATKAHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDSSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31696..32181)
                     /locus_tag="ACL3S0_000424"
     CDS             complement(31696..32181)
                     /locus_tag="ACL3S0_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGR1311402.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32456..32695)
                     /locus_tag="ACL3S0_000425"
     CDS             complement(32456..32695)
                     /locus_tag="ACL3S0_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311403.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILSHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(32940..34010)
                     /locus_tag="ACL3S0_000426"
     CDS             complement(32940..34010)
                     /locus_tag="ACL3S0_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1311404.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENAFQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(34007..34780)
                     /locus_tag="ACL3S0_000427"
     CDS             complement(34007..34780)
                     /locus_tag="ACL3S0_000427"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311405.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34777..35583)
                     /locus_tag="ACL3S0_000428"
     CDS             complement(34777..35583)
                     /locus_tag="ACL3S0_000428"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311406.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WLNLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35564..36721)
                     /locus_tag="ACL3S0_000429"
     CDS             complement(35564..36721)
                     /locus_tag="ACL3S0_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311407.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36881..37786)
                     /gene="murB"
                     /locus_tag="ACL3S0_000430"
     CDS             complement(36881..37786)
                     /gene="murB"
                     /locus_tag="ACL3S0_000430"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGR1311408.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(37898..38650)
                     /locus_tag="ACL3S0_000431"
     CDS             complement(37898..38650)
                     /locus_tag="ACL3S0_000431"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR1311409.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALEIVLVVYGTKEIFCKKS"
     gene            complement(38660..39391)
                     /gene="budA"
                     /locus_tag="ACL3S0_000432"
     CDS             complement(38660..39391)
                     /gene="budA"
                     /locus_tag="ACL3S0_000432"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGR1311410.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKESGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADIATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39533..40804
                     /locus_tag="ACL3S0_000433"
     CDS             39533..40804
                     /locus_tag="ACL3S0_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGR1311411.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40824..41639)
                     /locus_tag="ACL3S0_000434"
     CDS             complement(40824..41639)
                     /locus_tag="ACL3S0_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1311412.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVNGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41796..42449)
                     /gene="phoU"
                     /locus_tag="ACL3S0_000435"
     CDS             complement(41796..42449)
                     /gene="phoU"
                     /locus_tag="ACL3S0_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR1311413.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42461..43219)
                     /gene="pstB"
                     /locus_tag="ACL3S0_000436"
     CDS             complement(42461..43219)
                     /gene="pstB"
                     /locus_tag="ACL3S0_000436"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR1311414.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43232..44035)
                     /gene="pstB"
                     /locus_tag="ACL3S0_000437"
     CDS             complement(43232..44035)
                     /gene="pstB"
                     /locus_tag="ACL3S0_000437"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR1311415.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(44046..44930)
                     /gene="pstA"
                     /locus_tag="ACL3S0_000438"
     CDS             complement(44046..44930)
                     /gene="pstA"
                     /locus_tag="ACL3S0_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR1311416.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44920..45837)
                     /gene="pstC"
                     /locus_tag="ACL3S0_000439"
     CDS             complement(44920..45837)
                     /gene="pstC"
                     /locus_tag="ACL3S0_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR1311417.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45837..46715)
                     /gene="pstS"
                     /locus_tag="ACL3S0_000440"
     CDS             complement(45837..46715)
                     /gene="pstS"
                     /locus_tag="ACL3S0_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGR1311418.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47289..48593)
                     /locus_tag="ACL3S0_000441"
     CDS             complement(47289..48593)
                     /locus_tag="ACL3S0_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGR1311419.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48594..49367)
                     /locus_tag="ACL3S0_000442"
     CDS             complement(48594..49367)
                     /locus_tag="ACL3S0_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGR1311420.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49357..49635)
                     /locus_tag="ACL3S0_000443"
     CDS             complement(49357..49635)
                     /locus_tag="ACL3S0_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGR1311421.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(49635..50036)
                     /locus_tag="ACL3S0_000444"
     CDS             complement(49635..50036)
                     /locus_tag="ACL3S0_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGR1311422.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50246..50863)
                     /locus_tag="ACL3S0_000445"
     CDS             complement(50246..50863)
                     /locus_tag="ACL3S0_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGR1311423.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50853..51626)
                     /locus_tag="ACL3S0_000446"
     CDS             complement(50853..51626)
                     /locus_tag="ACL3S0_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGR1311424.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51637..52374)
                     /locus_tag="ACL3S0_000447"
     CDS             complement(51637..52374)
                     /locus_tag="ACL3S0_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGR1311425.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWKEIKKA"
     gene            complement(52379..53509)
                     /gene="hemW"
                     /locus_tag="ACL3S0_000448"
     CDS             complement(52379..53509)
                     /gene="hemW"
                     /locus_tag="ACL3S0_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGR1311426.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53593..53982)
                     /locus_tag="ACL3S0_000449"
     CDS             complement(53593..53982)
                     /locus_tag="ACL3S0_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGR1311427.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYALQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53955..54381)
                     /locus_tag="ACL3S0_000450"
                     /pseudo
     CDS             complement(53955..54381)
                     /locus_tag="ACL3S0_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            complement(54382..55170)
                     /gene="lgt"
                     /locus_tag="ACL3S0_000451"
     CDS             complement(54382..55170)
                     /gene="lgt"
                     /locus_tag="ACL3S0_000451"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGR1311428.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55163..56098)
                     /gene="hprK"
                     /locus_tag="ACL3S0_000452"
     CDS             complement(55163..56098)
                     /gene="hprK"
                     /locus_tag="ACL3S0_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGR1311429.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPKLLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56228..56404)
                     /gene="rpsU"
                     /locus_tag="ACL3S0_000453"
     CDS             complement(56228..56404)
                     /gene="rpsU"
                     /locus_tag="ACL3S0_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGR1311430.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56544..57251)
                     /locus_tag="ACL3S0_000454"
     CDS             complement(56544..57251)
                     /locus_tag="ACL3S0_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGR1311431.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57402..58430
                     /gene="queA"
                     /locus_tag="ACL3S0_000455"
     CDS             57402..58430
                     /gene="queA"
                     /locus_tag="ACL3S0_000455"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGR1311432.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(59091..60116)
                     /locus_tag="ACL3S0_000456"
                     /pseudo
     CDS             complement(59091..60116)
                     /locus_tag="ACL3S0_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(60949..61500)
                     /locus_tag="ACL3S0_000457"
     CDS             complement(60949..61500)
                     /locus_tag="ACL3S0_000457"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311433.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61850..62674)
                     /gene="nadE"
                     /locus_tag="ACL3S0_000458"
     CDS             complement(61850..62674)
                     /gene="nadE"
                     /locus_tag="ACL3S0_000458"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGR1311434.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADTMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQELGADPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62671..64131)
                     /locus_tag="ACL3S0_000459"
     CDS             complement(62671..64131)
                     /locus_tag="ACL3S0_000459"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGR1311435.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64247..64735)
                     /locus_tag="ACL3S0_000460"
     CDS             complement(64247..64735)
                     /locus_tag="ACL3S0_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGR1311436.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAGVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64725..64934)
                     /locus_tag="ACL3S0_000461"
     CDS             complement(64725..64934)
                     /locus_tag="ACL3S0_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1311437.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65320..66048)
                     /locus_tag="ACL3S0_000462"
     CDS             complement(65320..66048)
                     /locus_tag="ACL3S0_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311438.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLGFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            complement(66064..66934)
                     /locus_tag="ACL3S0_000463"
                     /pseudo
     CDS             complement(66064..66934)
                     /locus_tag="ACL3S0_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(67291..68019)
                     /locus_tag="ACL3S0_000464"
                     /pseudo
     CDS             complement(67291..68019)
                     /locus_tag="ACL3S0_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            complement(68279..68590)
                     /locus_tag="ACL3S0_000465"
     CDS             complement(68279..68590)
                     /locus_tag="ACL3S0_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGR1311439.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(68605..69891)
                     /locus_tag="ACL3S0_000466"
     CDS             complement(68605..69891)
                     /locus_tag="ACL3S0_000466"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGR1311440.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            70488..71072
                     /locus_tag="ACL3S0_000467"
                     /pseudo
     CDS             70488..71072
                     /locus_tag="ACL3S0_000467"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            71069..72259
                     /locus_tag="ACL3S0_000468"
     CDS             71069..72259
                     /locus_tag="ACL3S0_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR1311441.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(72773..73765)
                     /locus_tag="ACL3S0_000469"
     CDS             complement(72773..73765)
                     /locus_tag="ACL3S0_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1311442.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIREEVVQNSTYSMADYVSIYTSYIVSANGEKFSPYQTLTANSL
                     CTFDFDNIRDDFLFLLHENSYYLCVSIGFKRELLEKHLSSININPESFYGALLQTNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELSIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            73925..75679
                     /locus_tag="ACL3S0_000470"
     CDS             73925..75679
                     /locus_tag="ACL3S0_000470"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311443.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     TLLALTIIGGLILGAMMGEQEFMKIYQEALSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            75663..77384
                     /locus_tag="ACL3S0_000471"
     CDS             75663..77384
                     /locus_tag="ACL3S0_000471"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311444.1"
                     /translation="MKEFYKKRFALTDRGARNLSKATLASFFVYCINMPPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVKGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFNKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            77395..77979
                     /locus_tag="ACL3S0_000472"
     CDS             77395..77979
                     /locus_tag="ACL3S0_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR1311445.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            77979..78674
                     /locus_tag="ACL3S0_000473"
     CDS             77979..78674
                     /locus_tag="ACL3S0_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR1311446.1"
                     /translation="MPTFSSNAPFNPNPISKILVIFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            78662..80026
                     /locus_tag="ACL3S0_000474"
     CDS             78662..80026
                     /locus_tag="ACL3S0_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311447.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGKIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(80481..>80682)
                     /locus_tag="ACL3S0_000475"
     CDS             complement(80481..>80682)
                     /locus_tag="ACL3S0_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HGR1311448.1"
                     /translation="FLKVFEGAKARAIIMSLLETAKRHQLNSEKYLSYLLECLPNEET
                     LVNKEVLEAYLSWTKVVQEKCK"
BASE COUNT        24808 a        17181 c        14785 g        23908 t
ORIGIN      
        1 tgttttgagc tgacttcgtc agtcttatct acaacctcaa agctgtgctt tgagcaacct
       61 acggctagct tcctagtttg ctctttgatt ttcattgagt attacagtga acaatttttc
      121 tagctattgt aacaaaaaag tcactcgaag gcaacttttt tcgtccataa actttcaaaa
      181 gagaatggct tattcagaac taaaagccgc agctttttgc atttggtaat acttaccctt
      241 tctatccatg agttcttgat ggttaccata ttcaacaata tcaccatcta ctaagacaag
      301 aattaaatcc gcatcctgaa tggttgacaa acggtgagca atgatgaagc ttgtgcggcc
      361 cttcatgagt tttgcaaagg catcctgtac cagcacttct gtccgtgtat caatggaaga
      421 agttgcctcg tctaagataa gaatctttgg aatagccaga aagactcggg ctatggtcaa
      481 gagctgagct tggccgacag agagagattc tccagcattt tccaacttgg tatcgtatcc
      541 ctgtggcaac tgttggatga aaaagtctgc attagctgct ttggcagcag caattacttg
      601 ctctcgactg gcttcaggat tgccaaaggc aatattatca tgaatggtcc cttgtgtgag
      661 ccaggtttct tgaagcacca taccaaactg ctgtctcaat gatactcgtg tataatcata
      721 aatggattgc ccatccagca agatatctcc cgagctaatg ggataaaaac gcataaggag
      781 attgataaga gtcgattttc cagcacctgt cggaccaacg atggctacct tactaccagc
      841 tggaatatcg atagacaagt ccttaatcaa aattttttca ggatggtagc caaaagagac
      901 atgtttaaag gaaatagctc ccttaacttg gtcactggtc aagacttcct tacctgtttc
      961 agccacttca gggctatcta agactccata gatacgctct acgcaagcca gagcactttg
     1021 caactcagct agcactgaag aaatatcgtt aaagggcttg gtgtattgct gaacatagtt
     1081 caaaaaagtc actaaacgac cgacggtcaa ggttgaaccc atcatgatac gataagctcc
     1141 tactccagct aaaagggcat aaatgagtgc atttacaaag cgagtcgaag gattgaccgt
     1201 tgaagaataa aagatggctg actgagaata gcctgagtag ttgtcatgag cctcacgcaa
     1261 tctttggata aactctgttt gagcattgaa ggactggatt atagtctgct ggctaagcga
     1321 ttcttcaatc aaatgggtct gaatccccct cgtctctgtt tgcttctgga agagatgata
     1381 ggatctcttg gcaataaagc gtgaaatcac catggacagt ggcgtcaaca gcaagactaa
     1441 gagagtcatg aggagatgaa tttggagcat ggctagaata ctaaccaaaa tcatcaaaac
     1501 accaatgaaa aattggttaa aaatcatggt caagccagct gccaactgtt cgatgtccgt
     1561 ggttacacga ctgaccatct ctccattgcc ttgccgatcc gcaaaagcaa tcggtaaccg
     1621 atggagttta tggatgattc gctctcgtaa atctctggta taagagaaga ttagacgatt
     1681 atagaggaga ggattggccc attgtaccag agtatttcct attaccacca agagcatctg
     1741 gagaaaaatc tgccaaaaaa ttggtgatga accagccact aggacttggt caatgacctg
     1801 cccaatcaga ataggtaggt aaattgataa gccaacttgg gcaatagttc ctagaaaagc
     1861 taggaaaagg aggaagggat ggtttgctaa atctacggct aaacgtttga gcgtctggtt
     1921 tacagtttgt cgtttcattc tagtcctcct ttccatgttg ggatgcattg atttcacgat
     1981 agacttggct ggatttcatc aagtcatcgt gcttgccaac agctagcaac tcaccttttt
     2041 ccaagaggag aatctggtcc gccatctgta aagttgaggt tcgttgagag atcaaaatta
     2101 agctcgtgtt tggaaaattt tctctaatag ctttcaagag cttggactct gtaatggtat
     2161 ctagtgccga ggttgcatca tctaggatga gaaacggagc ttggcgcaag actgctcggg
     2221 cgatagacaa cctttgtttt tgtccacctg agaaatttcg cccccctgct tcaactagag
     2281 catccaagag tccttcctta tcactgacaa aatccttagc ttgagcaatt tccaaggcct
     2341 gccagagttc ttgatcagtc acttcttgat tgaaacctag agtcaagttg gaacgaatgg
     2401 ttcctttaaa gagttcgacc ttttgaggta cagaggcaat ccaagaccgc cactgctcca
     2461 aattaagagg actacgtcca ttttgataaa ggtcaatgtt ccccttgtct actggataaa
     2521 gtccaagtaa gagttgcacc aagcttgatt taccagaacc agtcccccca atgataccaa
     2581 ggatttgtcc ttgagtcata tcaaaggaaa tgtctctcag agaaggctgg gccgcatcag
     2641 gataggtaaa ggtcaattct tggacttgta aaacccgatc actggtaact tgcttttgtt
     2701 ctaattctga atggatatcc tctggagcct caacaaagac ttccttgatt cgcttggctg
     2761 agatatagga ccggttgaga gaattgatca acatggctag cttgaccaat tccaccaaaa
     2821 tctgtaagag gtaattgata agagcaatga gagcaccttg actgagcact cctccttgaa
     2881 ttgaaatata gccttgccag ataataacga gaagagttcc attgacaatc agataggtca
     2941 gaggtgttaa taaactagac cagaaacctg tcttttcttg taatctagca taaacttggt
     3001 taagggtttg aaaaatctgt aactctcgtt tttcttgacc aaaagcacga ataacccgca
     3061 tcccttgcaa ttgctggcgc gtttcctgaa ccagttggtc cgttttcttt ctgagactac
     3121 tgtagagagg attgaccaat cgcgataacc ctacaatgac aatggtcaaa atggcaacca
     3181 tgactaagaa ccagaaagtc aactcagctg agattcgata agccataaaa atggcaccaa
     3241 aaacgataat gggcgctcgt aaaaagagac gcaggaattg attgatacca gtctgaatct
     3301 ggtaggtatc cgaagtcaag cgagtgacca aactagaagt tgtcagacgg tctctgctgt
     3361 ccttgggcaa ggaaagaata tgacgataaa gatcgtttgt caattcctta gcaaaaccta
     3421 ctgctgcctt tgctgagtaa aattgagcta tcaaggccac taaaacgcca attactgcaa
     3481 agataaggag cagaccaatc tgcatccaga gatgaccttg atctccctga ggtaaagatt
     3541 ggtcaacaat cccagcaatc accatgggaa ccaagagctc aaaaacagct tctaacagct
     3601 tgaacaaggg ggctaaaatt gattccttga tgtagggttt gaagtaagat aataggtgtt
     3661 tcataaatcc cttttattca tattctagaa atgaagaaag tgggaaaccc caccctctct
     3721 gttttatttg tttaagtaag gcaatagata gccatatcct gctttttcca tctcatcctt
     3781 ggccacaaag cgtaaagaag cagaattgat acagtaacgg aggccgccta actcccgcgg
     3841 tccatctgtg aaaacatgac ccaagtgagc gctgcctgaa cgagaacgaa cttcaattcg
     3901 ctccattcca tggctcagat ccttgtaata atgaatcaac tctttggaaa tcggacggct
     3961 aaaacttggc caaccacaac ctgaagcaaa cttatccttg gcaaaaaaga gtggctcacc
     4021 tgtcgtaata tctacataaa tcccctcttc aaaggtttgg tcataggcat tggtaaatgg
     4081 agcctctgta gcagcttctt gtgtgacacg ataagactct tcagatagac tggccttcaa
     4141 cacctcttga ctaggctttt catagtttgc tgcatcaatc aatggcttat cagcatcggt
     4201 cacatcgata tgacagtaac ctgaaggatt cttcctgaga tagtcttggt ggtagtcttc
     4261 agccagaatg tagtggcgta attgctccac ttctactgca atctttcgac ccagcatgcg
     4321 ttcctgctcc tgcaccactg tgtagatagc tggcaaatct gcttcatcct gataataaat
     4381 cccagttcga tattggcgac cacggtcatt cccttgttga ttgatagata gaggatcgat
     4441 aactcggaaa taataaagta aaatctctct gagtgacact tccttctcat cgtaaatcac
     4501 ttggaccgtt tctgcatggt ctgtttcctt gagcaactgg taattggtcg tttcgacttg
     4561 accattagcg tagccaacac tggtttctag cactccagaa atgcgtgaaa aatattcctc
     4621 taggccccaa aaacaaccac ctgctagata aatttctgcc atctttattt ctcctttatc
     4681 acgtttttaa ctaatactct tcgaaaatct cttcaaacca cgttagcgtc accttaccgt
     4741 atatatgtta ctgacttcgt cagttctatc tgcaacctca aaacagtgtc ttgagctgac
     4801 ttcgtcagtt ctatccacaa cctcaaaaca ctgttttgag cagcctgcgg ctagcttcct
     4861 agtttgctct ttgattttca ttgagtataa acttcttttc acaaaaagga tatgaaaccc
     4921 tctggtcaag agtttcccca tcctatcttc tattctttat tttgcttcta cacggacacc
     4981 ttgggtatca actctcaagt catgcagttt tcctttgaaa ggttgctttt ccaattctgc
     5041 cttaattgtt ggcatcttgt catgagaagc cagaaccata actgtcggcc cagcaccaga
     5101 aaggtaggtt gcataggctc cattttcttt ggtcacttgc ttaatcatcg caaattctct
     5161 taccaagtcc tgacgatagc gctcatggaa gaggtctccc tcgattgctt gcccagcggt
     5221 caccatgtct cctgccaaca aggcagcaac cgctacattg gcgatagaac ttgcagcaac
     5281 agcttcctta taagacaatt ttttaggcaa gacactacgg ctgtcgcgag tacgtaattc
     5341 atagtttgga atgtaagcta gaaaatcaca ctctggaaag tctgctacga tagcagagac
     5401 ttgcccttca acagaacttg caataacgag attaccataa atggctggag ccacattgtc
     5461 aggatgccct tcaatcttgg tcgctaactg caatttttca tggtctgata agttgagttg
     5521 acccagttgg ttggctagtt caatcccagc aacgataacc gagctggaag aacccaaacc
     5581 gcgcgccaaa gggacatcac tggtcatttt caagcgtctt ggttgcaagt ctggtacaat
     5641 ttgtaaagcg attttgagca agagattacg ctcatcatgt ggaatccatt tgccaatctg
     5701 gtgttcaatc agccactcat ctcgttcttc gcagacctca atttgaagat acttggttac
     5761 agctacaccg accgagtcaa aacctggccc gatattggca ctggttgcag gtacaataat
     5821 cttcatctta ttctcctagc accttgaagg tattcaagag gtcgaattct gaaaccttct
     5881 tcaattcagc tgagacattt tcaagctggg ctttattaat cttgtgtgtg atgataacga
     5941 cacgcgcctt gtcaccctct ttgccatctt gaaggatttg cttaaaggaa atatcttgag
     6001 cattgaagat ttcagccaac ttcaagacct gaccttttga gtctagagcc aagattgaga
     6061 aatagtagtt tgctttgaca tcttcaggat ttgccaagac caagtcacgg ctatattcgt
     6121 tgaagtcttt gccaatagta ccatcattca aacgacgaac gatacggaca atatcagcta
     6181 caacacttgt tgcagttggt ttttgacccg cacctggtcc gtagtacata gactcaccaa
     6241 taccgataga ttctacaaag acagcgttca ttacgccatt cacactagca agtgggtgcg
     6301 ctttaggtag gaaggttgga gtcacttctg cagcaatacc tgaagaagtt tcctcaatag
     6361 aaccaaccaa tttcactacg taaccaagct cttgagctac agctacgtct tctggtgtga
     6421 tattgcggat tcccttgtgg gctacatcat caaaggcgat cttcatgcca aaggcaaatt
     6481 ggctcaaaat aaccatcttg taggctgcat caatcccatc tacgtcattc gtcggatcgc
     6541 tttctgcaaa tcctagacgt tgtgcttccg caagagcatc atcgtaagac cagccttctt
     6601 ccaccatctt ggtcaccatg aagttggaag ttccgttgac tactccaagc acgcgcgtaa
     6661 ttttatcaga agccaaggaa tttgctaaag tacgaagaat tggaatccca ccagcaactg
     6721 ctgcttcgta gtaaagtgct accttgttag cttgagcgat ttctagcaat tctgcgccat
     6781 ggacagctaa aaggtccttg ttagcagtaa caacgtgttt tccagcttcc aaggcacgag
     6841 tgataaaggt tttagcaggc tcaatacgcc ccatcaattc cactacgata gtaatatcct
     6901 ggtctgataa aatatcatcc acattggtta caaagttaaa gtcattccct gctgcaagca
     6961 agcgattttt ttcatcttca tccttgacca ataccttagc aactttgata tctgaatgtg
     7021 ctgattgatt gatttttcct ccattttcct ttaggaggaa aggcacacca cttgcaacgg
     7081 taccaaatcc cagtaaagca attttaactg tcatctttat ctcctcgaaa ttttctaata
     7141 tagccattat aacagaattt tgtgaaaatt cctattatag taaatcacta tttcagtata
     7201 aaaagaaaaa acgaatcaga cgattcgctc ttcttaaaat ctgaaaatag ctttccagaa
     7261 aggattagcc gattttttgc agattgagca ctgcatcgtg actcatcaag acttgaccat
     7321 actcttgtaa gactgagcga ctgatatcac tatcgtctgc aaactcgcgc atacgggcca
     7381 acagccaagc tggatatggg cttggatgat tttcaatatc cactaaaatg gtcaaataat
     7441 agcgctcgtt cattttgtag agttcagaag tttccatttc aaaagtcact gtcttggcaa
     7501 aaactaccaa gtcagccaac ttagcaaaag aaaggatgta gtagatgtaa ggttctttct
     7561 tactctcagc ttcttgttca gcctgctctt gctcttcttc cttggcttca acttgctcaa
     7621 gagattgaat ggcttcgata tcatccttgg ttttgtctgc gatgcttttt tccagggttt
     7681 tgataaattc atctggagac atttgagcca attcttccat atctggcaaa tccgataagt
     7741 cttcaaaatc tagattttgg tcaatctttg acttggtcac aaagacatct accttatcag
     7801 gttttggagt cacacggaag ctcaacatgc ctgtatccag aaagctatca ggcatctcta
     7861 gctcatccaa gatagcataa aagaactctt ctgttttttc ttgaggaacg agaaagtcag
     7921 caatctccat tccacgatcc atcaaatcct ctaaagacat cgtgattttt aaagttgtat
     7981 cactaatttg tttcattttc attgctagta acctcatact ttcagttcta tctattatac
     8041 tagattttta cgattttatc aaaagaaggc tcctctatac ggatagattt tccctagggt
     8101 ctttctatag gagactccaa gagaaaattt ctgcagacag atagaaaaag ccttcaaaat
     8161 cggctaagag ccgattttga agaccttata catcagaata cttataattt aaaggttgct
     8221 acaccgagga tagaacgatt taagtttctg agaatttgaa gactttgctc aaatttctta
     8281 taacgagtca ctccgtactc ttcaacaaga aggactgtat ctctttccaa aagagatgat
     8341 acatcctgta aatctacaaa atgcattcct tttaaagctt cttgactctg tttcaattta
     8401 tctaggatag ctttatttga gctaacgatg gtcaattcct gtccagtatt tttgtatgac
     8461 aaaacatctg ctaggttagc aattgttgta atctctgtta caaaatcaat ttgatactga
     8521 gaaaaatcac ctactctatt gattgttgga ttaaagagat aaactaacac atttcccatc
     8581 acaaccaaaa tcacacaaac cactccaata acaactaaac gaagaatcag atttttcaca
     8641 tttaagccaa gcgctgtttc accatttgcg ttcaattctt tagagttgat ggtttccagt
     8701 ttttcaattt ttacatttgc ataggcatgt ttaaatttct caatcaaccc atcaattttt
     8761 ttctctaaca agtcattggc atctttactt gatgtcaaaa ttttcacacc aacccctgca
     8821 tcgtcaatca tatagtagac ggtcaatttt ttccaccaat agtcattcgt tgaatttttc
     8881 aaggttgttt ctgtcgtgtc taattcactg gcaatttttt tcaactcact gggttctaca
     8941 tcattgaaaa gataagctcc attcaaatta ccatcaatca atttcccata aaaatcacta
     9001 taaccaccaa tttgatgatt caaaatcgtt ttggccgaat cttctggagg agtgatttta
     9061 tagataagat aagttgaata acttgttgta tctttgacag tgtttttatt cctaactgct
     9121 ttaattgtaa atggtacagc aatgagagca aataaagcga tgagagctaa aatatttgct
     9181 tttcgttttt tataaagatt tgcaaacaaa tcagctactg aataatgttc aaacatgatt
     9241 tttttctcct ttgtttagta gatactagtt ttcctttgta agcatttttg ctacaaatat
     9301 aatcacaaga acaattcccc agaattgcat tgtaaataaa ttgaagaaac tttctgaaaa
     9361 gctgcttctt ggcataaaga atagattatt caagatgagt agggataaag caaataggat
     9421 tgtccttgag cgataggcta cttgcagcat ggctataaat aatatgccga gtaagaaact
     9481 aagcagaaag actccaatca taccatagtc ggtatacaac tccatgatat aactacttcc
     9541 gataccatgc cctttcaagt attccttgtt caagacaaga taggatagat tgtgggcata
     9601 actattacta tcaatagcta gttccacact attggttgta tgttcaaagg cttttcctcc
     9661 gaaaatggct cccaaactcc cccttgcaaa ataatcaaga acaggaccaa aagtaaaatt
     9721 acggaaatct cggtaaggga ggctactgtt aaatagaaaa cctcgagcca gaacaccaaa
     9781 actagtccct tgtttataga taaagtcaag taagatatcc cagaaacctg tatgggaaac
     9841 ttggacatta tcccgtacat aattgagtac tcccatcgct aacatgagaa taggagaacc
     9901 tacaaaaatc gctaactttt ctttaaaccc aatccatttt cctttttcag cttgctcccg
     9961 cataaagtaa taaacaaaag caaataaaat acttaaaata aagggatttc gtgtcccaat
    10021 tgccaaatga atagtgttag ctgcaataaa ggagacaagc actgctgtgg cctgcaattt
    10081 ctttggcttg gttgccagat acatacacat tgcatagacc gtaaaggtag acaaaatgta
    10141 ggtaaaataa ggcagtttac tttcaaaatt tgcatagtag gcatagtagg aagtctgcaa
    10201 acgatacaag agccgttcaa ataaccgaat gaaatagaaa ggataagtta gaagaaaaac
    10261 tcctagtgat acaaagcgta accgcttgat ataaacctct tttagagaat ttcctatatt
    10321 tgctactttt attttcttcc tagctatgaa gtaacgagcc aggacgcctc ctgttgtcaa
    10381 gcccagaatc gaaaccatga caactataaa ggcaaaacga taggctattg gatgataggt
    10441 atccaaagca ccatccctaa aataatcaat ggtcggtctt gataccagaa atacaaaaat
    10501 ggttaaatag aaaataaaat ggattaagta atacttgata tcattccaac aagcaatcaa
    10561 gctactaacc aacaagaaca ataaagtaga aagtaagcta acattattat tattaaacag
    10621 atacacaatt ccacttacta gcgtcaaggc ataactgact atggtcaaac taaataataa
    10681 tcgtttccca tcaatcactt ggtcaccccc gttctaatgt aattttttag atttttcaat
    10741 atttttcagt aataagaatc ggtataagga aatatttatg aatagggcca aagcactaat
    10801 tcttctcccc ttacggaaaa ttgaattcct agaaatagca aaggcatggc cttttaaaaa
    10861 acgatgaatc tgagaatagg cttcaaactg tttatactga tcatctagca acatcttatc
    10921 cagaataaag aagtgggcat aggccaatct gaaaaaagcg acctctttca agtcaggata
    10981 gtttttcaca acttcattat aaaacttttg gtagatatca atataggcta aatccttctc
    11041 tgcatagggc ttggtcgtaa tactatcccc tctatggaaa tagtaataat agggtttagt
    11101 attaaccaca tacttcttgg ccaacttgat taaatcaaaa tggtaatagg catcttcgta
    11161 aatcaacccc ttaggaaagg ataggtcagt tgcaatctgt ctcttgatta gcttattgca
    11221 aatcgtccca ggtatttttt cacctatgag gtattccttt agaaatgttt gagaatcaca
    11281 gacaaaatag tcatcctgat tggctgactg tgggctttca tcattagcat agacattcat
    11341 gacaccacag ctcgaaacat ccgcatcttc ttgaactaat tgctcatata agctctgaat
    11401 catttctgga tggatataat catctgagtc aataaaaatc agataatccc cgtgagcctg
    11461 cttcatccca tcatttcgtg cttgcgacaa tccttcgttc tttttatgaa gcactgacac
    11521 cctgtcatct tgttcagcga ttgaatcaca caagcgacca ctttcatctg ttgcaccatc
    11581 atcaacaaga ataatttcca gattttgata ggtctgcttc tgaatggaag ctatcgattt
    11641 ttctaggtac tgcgccacat tatagactgg cacaatcaca ctaattaatg cagtttccat
    11701 gctactcctc taatagtttt tctacttgtt cgatttgttt tgtaattgta aattgttgaa
    11761 tgaattggct agcctcatcg acatcaaagt ttgaggcaga agtcatgtaa ttagtaatcg
    11821 cctgagctgc ctcttgattg ctctcaatga tttgtccaaa tcgtccttct tgggataatt
    11881 cctcagcccc tccaacgtcc gtagagataa aagggagtcc cagactcaag gcctccacat
    11941 acactccagg aaaaccttct tgtttagaca tagacaagag aactttcgtc tgagatagat
    12001 actgataagg atttttttga taaccaagga aatgtacata gtcctcaatc ccatactctt
    12061 tgactcgttt tttcagttcc tcttccatat caccagcccc gataaaatag agatgatagt
    12121 tttttccctc ttggtataat aatcgtatca cttccactac acggtcagaa cccttatttt
    12181 cctcaatccg tccgatagta cagatacttt gaggagcaat ctcgatatcg atcttctctt
    12241 gagatttttc tagaatagtc tgaaaatcat atccattgta gattgtctgt aatttagaag
    12301 cataatctgg ataaacttcc ttgatagaat tgctggtctt ttttgaaatc cctacaattg
    12361 tattcgcagc atccaactgg cttctatgtg attctctttt agagctatcc ttaagaagtt
    12421 cttcaatact tccatgaatc caagatatct tcttgacttc tcttctttta gagaacaaca
    12481 gtggtggatt cataatggta aaagaaactt caacatcata atcatctttt acaagcaaac
    12541 gacgagtcag tcttggaaaa taaattctca ttctccacaa aaaagctcgt aaccatctgg
    12601 tttggcgata atcttgaagg gattttaaaa tgcgtacatg ctttggaaca gattcatatc
    12661 ccttgtcaaa gtgctccatt tcaagaatat caatatcata cttttctgga tccagatttg
    12721 aaacaatagt tgatagaatc ttctctgcac cacctccaag agaaaaagac cacataaaaa
    12781 ataagatttt tttcttagcc accatattct cccttgtatt ctgtataaga cttatccata
    12841 tcagcgatga cagcatcatg atgcggtacc tgcttgtctg ctggtggagg cgtcatataa
    12901 tccccaaaag cagttctgag atagacatca tagccgattg gaataggcat ctctgttcct
    12961 tcaaatggca agaaaagatt gtcttcaaaa gatgtgattg ggtacttgtt tctcatgtag
    13021 ccaggacctg agcataattc tgtaatgcca tcacaatcag ccaaatcata cttagtcatt
    13081 tctttctcag cttttttcca gatgcgataa cggagagatt ttggagtcaa acccagtaaa
    13141 atgcaacttc cccatttcat gagagcacca tgcttttctg gaatagtttg cgcacaaaag
    13201 agtgaataaa tcaaggccca acgaacctgt tttttccgct cagctggatt tttcggataa
    13261 taatccaaag gcaaaacatc caaggccaga ccatgtggca aatccaaatc ctgctgataa
    13321 ggcttgatac aggtggtttt cttgtcacga atggtaataa aaagattacg atcaacaaaa
    13381 tccttgtgac tctttgacaa gaaataacgt tcatctgcat aacgaggcca taattctgct
    13441 aatttctcat aatctttacg aggcataaaa aagtctaggt cgtcgtccca aggaataaat
    13501 cccttgtttc gaagggcacc aatagcgcct ccgccacaga gataacagag caaatcatgt
    13561 tctttacaaa aggccacaaa atattcagcc atctccagac tacgagcctg aattgctttt
    13621 aaatcagtca tattgttcat tattctttct atcgtatcgt ttcattatac cacaaacaag
    13681 gggtgaaaat ctattgcaga ctgtaaaaaa tcaaagcctg actgctatcc aaatagctat
    13741 caaactttga tttttctgtc ttatactctt cgaaaatctc ttcaaaccac gtcagcttca
    13801 ccttgccgta ggtataggta actgacttcg tcagtcttat ctacaacctc aaaactgtgt
    13861 ttttagcagc ctgcggctag cttcctagtt tgcactttga ttttcattga gtattatctt
    13921 atctcaagcc catttgagcg agcttggttt gatatttgtt ttgatcaacc agcaagccca
    13981 agcctccata aacatcatag gcatctaccc agtcacccag ttctggaatc gtcaattttt
    14041 caataccatt ttttgctcca tccaaaacag ataaaccgtt tgttaggagg aaagtataag
    14101 gtacgttggt tgaggtcata gcaaaaacct ttccaagagc ttcagaacca gtgaaaagtt
    14161 tagtgggatc tttaatttgc tctaaaattg ctgttaaaac ttgttgctgt ctttttgtac
    14221 ggccgtaatc cgcctcatca tcatcacgga aacgagcata attgagcagg gtcgagccat
    14281 tcatctgctg ttttccgact ttaatggttt gggttggaga ctcagtctcg gtagcatata
    14341 aatcatctcc gactgtagct tctgttaggg gacgcccatt caatgttgaa aattgagcat
    14401 caatcgtcac cccatcaggg aaaagcgtgt caatcgctgt ggcaaaggcc tggaaatcaa
    14461 ccaaggcgta gtacttaatg tccaagtcaa aattatcttt caagacttgg cgaaccattt
    14521 ctgccccttt ttgcccctct tgttctccta actcgtaggc tacgtttaac ttgttatctg
    14581 tctgttttct accattaatc acttgactat aaccatctat atagaccaaa ttatcacgca
    14641 tgaaactgac tagcttcatt ttcttatctg agcccccgac atttaatacc ataatagagt
    14701 cagttcgtgt ctcaacactg ttctggccga ttcgaccatc agtacccatg attaaaatat
    14761 taactccatc tctagtgtcc tgaccattaa agacttctac ttgagctgcc cgggcatcag
    14821 cagttttctt tgcgctagca tcttggtaac cacgcaaaaa catgaatacc atggccaaag
    14881 ccacacagac caaaagtgaa aaaatcacca taaaaattcg tttaagacgg agcttccgtc
    14941 ttttcttttt tggagggaaa gagagtgctt gtgatttgga ttgtgagcga ctccggttcg
    15001 catagcttgg taagtcaacc tgctcttctc tttcttgttc caagctagag ctactatttc
    15061 ccctagcaag agttagcttt tcttgcaaat aggcaaactc atttttttct ctctcattga
    15121 gatagtgaat attttttagc aaataatcat aacgcaactg ctcatgatga cttaagggat
    15181 tttctttact catcttctct cctttccatg gtctgatatt ggataaatag gataggcacc
    15241 cagaatttta tactggattc caatcgcttc taattctttt tgggcaaagt ggaccaagtc
    15301 cttatcggta taatccacat cgataatgaa aaagtattca cccagtgctg tcttgagtgg
    15361 acgactttca atttttgtca agtcaattcc tcgccaagca aaggtcgaca gggccttata
    15421 aagtgcacct ggaaggttgt caggtaatgt caaggccaaa ctcatctttt cagtttgtgc
    15481 ttgcaaggga atactaggct tttcagctcc tagaacccag aaacgtgtga aattggcttc
    15541 catttcctga atatcctcgg caatcagttc caatccatat tcttcagcag aacttctagg
    15601 tgcaactgct gcaaagggct ggtctggatg ttcggaaata aaacgggccg cataagctgt
    15661 actagctgtt acctcgattt gagcctctgg atattgttca tcgatgaatt tctttccttg
    15721 agccaaggcc tgtggatgtg aaaaaatctt ttcaatctta gtatggcctg gaaccaccat
    15781 caactgctga tgaataggct gaacgatttc tgctactgct tggatgtgag cctgatgaaa
    15841 aagatagtcc aaggtttcat gaacactacc ctcaatagaa ttttcaactg gcaccacaga
    15901 atagtccact aatccttgct cataagcctt gatgacatct gtaatgttgg caaaagcctg
    15961 caattcctca tgaggaaaag ctgtctgcac aacgtggtgt gaaaatgatc ctttgggacc
    16021 tagataagca attttcatct tagttcctct ataatttcct ctgggcttag cttggtcaca
    16081 tccaaaaccc gactagccac ttcctcatac caagcctgtc tttcttgaaa aatagctact
    16141 agttcttcct tgctattatt tagaaaaagc ggtcgctgat tgtccttatc agctgcgata
    16201 cgttggtaga gggtttcaaa atctgctttc aggtagatgt tatctgtatt agtcttgagt
    16261 aagtcacgat ttctctgaga aataaccact cctcctccag ttgacacgac ttggtctgtt
    16321 tgtagtaaat cagctaggac ttctgattct acctgacgaa aggctgcttc tcccttttca
    16381 gcgaaaaaat tcgcaatgga catacctagg cgcttctcaa tcagagcatc catatcaagg
    16441 taattagggt ccaagcctct tgcaatagtc gattttccag cccccataaa ccctaataac
    16501 accttagcca tgaatcaagc tctccaaatc atcaaagaaa ctaggatagc tggtattgat
    16561 ggcttctgca cggtcaagct ccacctctcc acctgcaacc aatagggctg cgatagctgt
    16621 catcatgccg atacggtggt caccaaacgt attgactcta gcaccgtgaa gagctgattt
    16681 tcctttgata atcatcccat ctgccgtagg agtaatatct gctcccatac tatttaaggc
    16741 gtctgccaca acctgaatac ggtctgtttc cttgaccttg agctcctcag catccttgat
    16801 aactgttaca tcttgggctt gggtcgcaag tagggcaata ataggcaatt catcaatcaa
    16861 acgtggaatc aaagcgccac aaatctctgt tcctttcaag tcagaagact caacaatcaa
    16921 ggttgcagat ttagcgactg gatcgatttc agttatttcc aattttccac ccatggcacg
    16981 aatgacatca ataataccgg tgcgagtttc gttgatcccc acattctgca gcactagacg
    17041 agaatttgga gcaatcaaac ctgcgactaa ccaaaaggct gcactggaaa tatctcctgg
    17101 tacgaccacc ttctgtcctg tcaatttttg tggcccttgg actgtgattt tcttaccgtc
    17161 cacacttaaa tgaccaccaa attgttgcaa catatcttca gtatgattac gggtgtactc
    17221 tttttcgata ataactgact cccccttagc ttgtaaggct gcaaacatca aggctgactt
    17281 gacttgggca gaggcaattg gcaactcata atgaataggt cttaggtttt tcgtcccttt
    17341 taagcgaagg ggaggcaagt ctcgttcagt ttgtcctgaa atgctgacgc ccattttttt
    17401 cagtggaagg gtcacacggt ccataggacg tttggaaaga ctatcatctc caaacatctc
    17461 tacttcgaaa tctgcaccag caaggacacc tgaaatcagg cgaatcgagg tgccagaatt
    17521 tcccatatta agggcatttt gcggcgcttt taagccagcc atgcctacac cttgaatggt
    17581 aataacccca tctttatcct caatttcaac accaaggtca cgaaaaacct gcatggtcga
    17641 aagaacgtct tcacctcgca gaatatcata aaccttggtc tcaccctcag ccaaacttcc
    17701 aaagataatg gaacggtggc tgatagactt gtcacctggg acgcggatac taccatgtaa
    17761 atggcgaatg tttgttttta gtttcatact ggacctcata cttgcaatac ttttacctat
    17821 tttatcataa aaagccagaa attccttaaa aattcctgac tttaggatag ttcttttctt
    17881 atttcagcaa ttctgaaact ggttcaaaaa caattttttc aatgtcagaa aggtaaatgg
    17941 ccaattgttg ttgcttggta aagaattctg acaagaggct atttccttga atctgtttac
    18001 caaagccttc catcttagct tggaaggacg catctggcat ttgacctgtc tgtgctagtt
    18061 tttgaatttc ctcttgaaag gcaagatatt ctgtaaagat tttgcttgcc tcagcatctg
    18121 ctgcaatcgc atctttagct gctttaacag ccttgtattc tggtaatccg cgtagaccgc
    18181 gactgagttc gtttgcacta tcgtaaatat ttgacatgtt cttctcctta tttgatgacg
    18241 actgtatagt cggtattttc tgttatgaga tgctcagctc tttccaagtc ttgagcattt
    18301 ttaaatgaaa tttgtaggat tccgtgaata tcctcacgat tttcctcgtt gatgtggatg
    18361 ttaaccaagg aagttccacg tagcagttcc aaaatccgca ggatgacatc ttcttcatca
    18421 ggaacgtcaa catagaggtc gtaagagcta tccacaccac cacgcttatg gatttccatg
    18481 gtctggcgtt gttcacgcgc ttggttaaaa aagttccaaa tttgctcttc atctccctta
    18541 ctaatggcct gaccaatcac ttccaaacgt tccttgaaat cctcaattct atccagaatg
    18601 gtctcgctat tggacaagag aatggaggtc cacattcctg gctcgctttc cgcaattcgg
    18661 gtcatatctc gaaaaccacc tgccgcaaag cgccttgcca tctcatgctc ttgagcatag
    18721 accgcagtct gctccatgag actagaagcc aaaatatgag ggaaatggct aatctgagaa
    18781 gtgacacgat catgctcctt ggcatcaatc tcgataaaac gagcatgaag acctgaaagc
    18841 agatccttca tttccttaag cgtgtcctga cttgtcaggc ttgaaggtgt aaagatataa
    18901 taggcatttt caaaaagatt gacatctgcc gaagcagccc ctgtcttgtg actaccagcc
    18961 atgggatggg ccccgacaaa gcgaacagac ttgccagcca aatactgctc cgccgcatcc
    19021 acaatggttg acttggtcga accagcatct gaaataataa cgccttctcg caaatccaaa
    19081 ttggccaact ccttaatgaa agcaatagtt tgtttgattg gcaagctgag gataatgaca
    19141 tctgccaaag gagcaaaact agcaaaatca tccgttgcac ggtcaatcat accttctttc
    19201 aaggcgatat ctctcgaagc ttgactacga ttataaccta aaatttcata atctggatga
    19261 tcgcgtttga taccaagtgc catagaggct ccaatcaacc caagacctgc gatatagatt
    19321 gtttttgcca taggaactcc ttaatagttc tttgtatagt ctcggtgttt ggctaccgct
    19381 tcttttagtt cctcaagatt atctgatgag aatttttcga ggatttcttg cgccagaacc
    19441 gttgctacaa ctgcttccat gaccattcct gcagctggaa gagcagtcgg atcacttctc
    19501 tccacggttg ccttgtaagg ttcgtgggtt tcgatatcca cactcataag aggtttataa
    19561 agagtaggaa tgggtttcat gaccccacga acaacgatgg gttgcccatt agtcatacca
    19621 ccttcaaaac cacctagatt attggtacgg cgagtataac cgtcttcttt agaccagaga
    19681 atttcatcca taacttggct gcctttacga taaccagcct caaagccaag accaaattcc
    19741 acccctttaa aggcattgat agagacaaca gcttgagcca atcttgcatc caattttcta
    19801 tcccattgga cataggaacc aagaccaact ggaacgcctc cgacgactgt ctccacaacc
    19861 ccaccgatgg tatcaccatc acgtttgatt tggtcaatat agtccttgat ttcctgttct
    19921 cgttcttggt tgacaataga aacttcagac tgggcagctc tttgcttaat ttcagcgact
    19981 gtcagatttt caggaacatc tatttcctta ccaccaaaga ccacgacatg gttggcaatc
    20041 tccatatcca gctcagccaa gaggcgtttg gctactgcac caactgccac ccgcatggtg
    20101 gtttcacgag ctgatgaacg ctccaaagaa tttcgcaaat catcaaaacg gtacttaatc
    20161 cccccaacca aatcggcatg acctgggcga ggatgagtaa ttttccgctt gcttttaagg
    20221 cggtcttcaa tgtcctccgc agacatgatg tccagccatt tctggtggtc cttattgatg
    20281 acatccatag taataggcgc ccctgtcgtc ttcccgtggc gaacgcccga agtaaagaca
    20341 acctggtcac tctcaatctt catacgacca ccacgaccgt agccaccctg acggcgtcta
    20401 aggtcctcat tgatatcctc agctgtcaat ggaagtccag ctgggattcc ctcaataata
    20461 gctgttagac gggggccgtg tgattctcct gcagttaaat atctcataca ctctccttat
    20521 tttaccaagt agtctttcat ctcttccaga gaaactgggt gaatgatcgc tgaaccaagc
    20581 tctggcacca agaccaattt caaggtgtta ccacgcgctt tcttgtcatg agtaagagcc
    20641 tgataaagct tgtcaacttc ccaattttca tagtcaacag gcaagccgaa tttctgacac
    20701 atctctgtga tagattgggt aatgccagct ggcatgaggc ctttttcctc agcaaccttg
    20761 gaaatctgta ccattcccat ggcaacagcc tctccatgca tgaccttgcc ataaccggca
    20821 gtcgcttcga tggcatggcc aatagtgtgg ccaaaattga ggtaaagacg aataccattg
    20881 tccaactcat cttcaaccac catcttgcgc ttcacctgac aagaatgttc aatcaaggtc
    20941 tctgcatgtt ccaaaatact ctcaacagaa ccattcagtc ccgtcaagag agcccacagt
    21001 tctggatcct caatcaagcc atacttgata acttcaccca tcccttcaat caactctctt
    21061 tttccgaggg tttcaagaac aagtggatca atcagaaccc catctggttg ggcaaaggtc
    21121 cccaccatat ttttagcaaa tggtgtgtta acgcctgtct ttccaccgat agaagaatca
    21181 acctgagctg tcaaactagt cggaatctga acaaagtgaa taccccgcat ataggtagag
    21241 gctacaaagc cagccaggtc cccaacaacg ccaccaccaa gagcaacgat tccatcgcta
    21301 cgagtcagac cttgcttgac tagaaattca tagactttct gaacagtagt taaattcttt
    21361 ctttcttcac cttctaagaa atcaaaaaca gctacctgaa aaccagcatc ttctaggctg
    21421 agcttgacct tctctgcata gagagaggct acatggttat ctgtcacaat gactaccttt
    21481 tgcggttgcc agagttctcg caaccactga ccagcctggg ccatacaacc tttttcaatc
    21541 tgaatatcat aaggatgatg aggaatatcg attctgattt tcataggaga gtctcccttt
    21601 ctttattggt atttttctgt taaagactgc caaatctctt ctgtcggcat ttccttgcct
    21661 gtccacagtt gaaaagcttc tgcagcttga tagagtaaca ttcccagacc attgactgct
    21721 ggattgccct gacttctagc ccatttcaaa aacggtgttt caaagggttg gtatatgata
    21781 tctgcaacta agagagtttc tggtaagact atgttttcag gaacaggaga ggattggcca
    21841 tccatgccca cactggtggc attaactagc aaatccgact cggcaatcct tgcttgcagt
    21901 tcagaaacat attctaaagc acacaaatcc actttaaagc ctgtctgctc ctgtaacttg
    21961 tctaggtaag gtcttgtttt ttccatagaa acggaacgaa caaagaccga aatctgactg
    22021 acgccatcca aaatagcctg tgccaagatt gatttagccg caccacctgc acccagcagg
    22081 gtcatctttt tacctgaaat tgtaaaagaa ggcaagcact taaaaaatcc cttgccatct
    22141 gtattatatc caattaaatt gccattctca ttgacaaccg tattaaccgc accaatcaag
    22201 cgcgcttcat cgctcagctt atccaaataa ggaatcacct gctccttata gggcatggac
    22261 agattgatgc caaacatctg gtagcgacga atattggcca ctgtttctac caagtcactc
    22321 gcttcaatct cccaagccac ataagcaccg ttggtatctg tcgcctcaaa ggctctattg
    22381 tggatgaagg gagaaataga atgcttaata ggattggcaa caactgcagc taaacgtgta
    22441 tagccatcaa gcttcatcca aaatctccct gatttttttc atgctagcta gagaaatctg
    22501 cccaggggca ctaacctcat ccagactggc aaaagaccaa ctcgaaccaa tcacatccgc
    22561 agtgatacga gagaccttgc ccaccttacc catagaaatg gtcacatatt cctgttcagg
    22621 attgagggtt ttaaagcctc gtgtatagtt catcaagtct aagacatcct gctccgtgtg
    22681 agccatcacc gcaaccttaa caagttttgg atttaggatc gtcaactctg acaagatttc
    22741 catcatgttc tcaggtgttt cttggaaatt atggtaactc aaaacaagat ttgggaagtc
    22801 cagcatttcc tcaaaaacat ccttgtagct atagtactca aaatcaatat agtctggttg
    22861 atagagttgc gcaacttcct tgattagatg gatatactct tctggagaaa ggtcgatttc
    22921 tccaccttcg gagcgagttc gtagcgtgaa aaccaactca cggcctgcga atttttcaaa
    22981 aatggctgga gctacctgca aaatcgcttc tttaggcaga tagtcggcac gccattcaat
    23041 gatgtcggca tccagatacc tcgtggcatc cagagcctga gcctcctcta aacttcttgg
    23101 cattactgaa acgattaatt tcatttacta accttcatac taatcacctt gaggtaatta
    23161 ctactttcat cttttttatt ataggcaaaa tctgctggaa gaccatattt gtttaaaatc
    23221 tggtaacttc ttcctgcaaa acctttatca atttgttctg taaatttctg gcgggaaaca
    23281 ttggcagcat tggtactggc aatgataatc cctcccggat ttaaaatctc aagactctgg
    23341 gaaatcaact tgtgataatc cttggccaca gagaaagttt gttttttatt ccgagcaaag
    23401 ctaggcggat ctaggacaat cacatcgtag gtcaagtctt tgcgtttggc atatttgaaa
    23461 tactcaaaga catccatgac tataaaacga tgctcgtctg tgctgagccc atttgcctga
    23521 aaatgcgctt gagacaattc tcgtgaacgt ttggctagat caacagaagt tgtctggcta
    23581 gctcctccca tggccgcagc tactgaaaaa gccgctgtgt aggaaaacat attgagcaag
    23641 gatttaccca tagtcaagcc gtcaactaaa ctaccgcgaa cctcatgctg gtctaggaaa
    23701 attcctgtca tcaagccatc attcataaag acttgataca ggacaccatt ttctaaaaca
    23761 gtgaaaaagt caggtgcttc ttgaccataa acatgggcag attcatagtc aaaaccctta
    23821 aagcggattt tctcataagc ccctaaaacc tcagggaaaa cctgtctaaa ggcttctgat
    23881 atagtctgac gaatctgata aacataagag ttataccaag aaaagacggc gtagtcgcca
    23941 taaaggtcca ctgtcagacc cccaaagcca tctccctctt gattaaagag acgaaaggca
    24001 gttgtcaaat catcttgata gtaggcgttt ctcttttctt tggcttttct aaacaacgtt
    24061 tcaaagaaag tttgattgaa ggtcaccttg tctttgctga caaaccagcc caagcccttg
    24121 ttttgctgag aaaggtaggc agtcccaaga aagtttcctt cctgaccctg cacctctact
    24181 tcctgatcct taagattgac attctcaaga tcactggctt ctagtaaaac tagcccctta
    24241 gcaagcttct tttcaaccct tttgctgact cttattctat tcataactac cattatatca
    24301 aacttttaga caattctcaa aaaagaaact acccttgctt ttttactctt cttttaaaaa
    24361 atggtatact agacttcctg caaaactagg aagtaaatgt gtaagaatca caataaaaaa
    24421 tgctcttccg tcttggagga gcatttttta ttatcaacga aaatcaaata gcaaactatg
    24481 aaactagcct caggttaact gtgagattat aggtagagag gttgtatcag caatatgtgt
    24541 ctgtcaaatt tagtgacaaa ggtagtagaa gaaagatgaa gaaataaatc agcttcagta
    24601 gatatctgga aaatttgatt ttatagagaa gccttttgtt acaaactcaa tatactatca
    24661 ataaataata ttatagaagc aacaataatt ataatttcac ctatttgcat cattctattt
    24721 cgaactctaa atatatgttc tatcaaaaat acttggatca cacacattat aggaattaac
    24781 gtttttgaaa ttgaaaaata tcccaataaa taaactataa acaacaaaaa tagaactatg
    24841 ttatatttct tattcaaaac attcctccct atatttttga ttaccaatct taatcattta
    24901 caactacatt ctaacaaact ataaaagcgt ttgtcgaatt gaatttatca agcaagcgac
    24961 caaccagctc atcttttttc tatttctgcc aatatgcgtg acaggtaata atgatagcca
    25021 aaaatagcaa gagcaagcag gaggataaga gctcctactc ccaagctgat ggcaaggata
    25081 gtggagagag actgaaccaa gaatatgctc ccaattacaa gggccatcag gattgcacta
    25141 taaataaaca ataaaactat ggcgactatg ccatttgaac gattcaccag gtccgtaatg
    25201 ctactccaat tgattgacag atttttaacg tccttaaagt aatggtggca agaaaggatg
    25261 acactggcaa ggatccatgc cataataagg taaatcatcg aaatgatggg caagcctaga
    25321 tatagagaaa gaccaagtaa agtcagaatt ggtaaaaagg actggacggc atatataatc
    25381 caaaatttca ctttcacata acgagcaaag tcaaagggta aactcttcag aaaatcaaca
    25441 ttttccctct ccaaggacaa ggcaattgaa tgcaggctgg tgatattgtt attgacaact
    25501 gctataaaga gagctataaa aaacaagggt aaccagtatg gaggatgaat gtctggaact
    25561 atctgagaat ctcggatttt ggaaatcaga ccgatcatca tgagataagg aaggaaagca
    25621 cttgtaaaaa gcactgtaac cacgccagta ccctgtccca agagggtgag gtggtagcgt
    25681 aaaaccatgc ggaaaaatcc ctttttagtg gttgaaattc tctccttgct gcgacgttct
    25741 tttttgacct tctcctcact attaagcagg atcacgtcat aaaaacgagg aaggaccttc
    25801 tttttggtca gataaagcag gaagagagtt agtcctatcc aagcgagcag acccactaag
    25861 gcttctgtcg aaaaaggctc cactgctatt ttgtaaaaga tatgaagagg ataaaggaga
    25921 aatggaatgt ctctaacttt gtcaacaata cttccaaaag tcgactgtag aaagaagaca
    25981 aatattaaag gtatgagaac tcctatccca atcatcacat tcgaaaaaat agactgatac
    26041 tttctgaagg ccgtagtttg agccaagaaa tgcactgcca ctaccatcac tagagccaca
    26101 gagacaaata ataaggtcaa ggacagtagc atcaaaggca aacccagcca aagagaagga
    26161 gctagactaa tatagagggc tagaaaataa gctaggattg gtacaattcc agttagagct
    26221 ggcaaaagga cagacagtcc tttagcaatt ataatctctg attctttaaa ggcatagggc
    26281 ctataggagg ccaggtcctt actctcataa aagacattgt aaaatgcagt taaagaagtt
    26341 gaaaaggcaa tcactagtaa aatagcaacc acaaaactaa aataaacagg catttcctca
    26401 aaaggaaaat gaatggctat agtactaaaa aagatgagca tcaagagact ggaaaaaatg
    26461 taagaactta ggactctagc ggaaacattt actttttttc cagtattttt agcttgcttc
    26521 tttcgtaggt tagccagatt agcttcttga gatgaataga ggatattgat atcaactaat
    26581 tttttaatga ccttgagacg catctgaaac ctcctctttt ctaccagcaa ggctaaggta
    26641 gatactttcc aaagactggt ctgggttgtc tcttctcaag tcctctacct taccacaata
    26701 aatcaaatgc ccctttttca aaatagcaat ccgatcacag acttgctcag ctacctctag
    26761 gacatgagtt gaaaacaaaa ctgtcttacc tttttgcgca tgctccttca tcatttgctt
    26821 caaatcaaag gcagcctggg gatccaaacc agtcaagggt tcgtccaaga cccaaatatc
    26881 aagatcagac aagagtgccc cgatgacaaa aactttctga cgcattccat gagaaagggt
    26941 ttcaataacc tgataacgat tttcagcaaa atcaaaaacg ttcaataacc tagctaaact
    27001 agcttccaag tcagagctgc tcaaatcata ggatgaagca atcaattccc aaaattcatt
    27061 ggccgttaaa cgtaaaaata agtcaggcga gtctgctacg tagccaatct ttcgtttgat
    27121 cgccaagcga ttttccgata aatcctgacc atctaccaaa atacgaccac tgctgggtga
    27181 aatgatactg actagggatt ttatggtggt cgattttcca gccccattat gaccaatcaa
    27241 gcccataatc tctccatttt caatctgcaa attgagatta ctcaaggcct ctttatcacc
    27301 atacaactta ctaacatttt gaaattcaat catgggacaa ctcctatctt tatctgtatt
    27361 atacatcgct atactagcac tttgatacaa aaaaatcaat actttatttt aagtagttaa
    27421 aatagtttcc ttctatctta cgcaaacgtt tgcgctaata gatactttat gatagaataa
    27481 agaacaagat tgacaagtaa gaggaaacat catgcaaaat caaacactca tgcaatactt
    27541 tgaatggtat ctgccccacg acggtcaaca ctggacgcgt ctggctgaaa atgctccaca
    27601 cctagctcat ctggggatca gtcacgtctg gatgccacca gcttttaagg caaccaatga
    27661 aaaagatgta ggttatgggg tctatgactt atttgaccta ggagagttca accaaaaagg
    27721 gactgtccgc accaagtatg gtttcaaaga agactatctt caagccattc aagcccttaa
    27781 agcgcaggga attcaaccaa tagccgatgt agttctcaac cacaaggctg ctgccgatca
    27841 cagggaagcc tttcaggtta ttgaagtgga tcctgtagac cgtacagttg aacttggaga
    27901 acccttcacc atcaatggct ggactagttt taccttcgat ggtcgccaag atacctataa
    27961 tggcttccac tggcattggt accacttcac cggtacagac tacgatgcca aacgcagtaa
    28021 atctgggatt tatctgatcc aaggggacaa caagggctgg gctaacgagg aattggtcga
    28081 taacgaaaac ggaaactacg actacctcat gtatgccgac ctagacttta aacatcctga
    28141 agtcatccaa aacatctatg actgggctga ttggttcatg gaaacgactg gtgtagctgg
    28201 tttccgtttg gatgccgtta agcatattga ctctttcttt atgcgcaact tcatccgcga
    28261 tatgaaggaa aaatacggtg acgatttcta tgtttttggt gaattttgga acccagacaa
    28321 ggaagccaat ctggactatc tcgaaaaaac ggaagaacac tttgaccttg tcgatgttcg
    28381 tctccaccag aatctctttg aagccagtca agctggcgca aactatgacc ttcgtggcat
    28441 ttttacagat agcctggttg aactcaagcc tgacaaggct gtgacttttg tcgacaacca
    28501 cgatacccaa cgaggacaag cccttgagtc taccgttgaa gaatggttca agccagcagc
    28561 ctatgccctc attttgttac gccaagacgg ccttccatgt gtcttttacg gagactacta
    28621 tgggatttca ggccagtatg ctcaagaaga tttcaaagaa atccttgacc gcctcctagc
    28681 catccgaaaa gacttggcct atggagaaca aaatgactac tttgaccatg ctaactgtat
    28741 cggttgggta cgttcaggtg ctgaaaatca atccccaatc gcagtcctta tctcaaatga
    28801 ccaagaaaac agcaagtcaa tgtttgtcgg tcaagaatgg actaatcaaa cctttgtaga
    28861 tttacttggt aaccaccaag gtcaagttac aattgatgag gaaggttatg gacaattccc
    28921 tgtctcagct agatccgtaa gtgtctgggc agtcaatacc atctaatagc tcataataac
    28981 caagctaggt ccaagcggat ttggcttttt tgtattcaca aaaagaccta cccaaatgga
    29041 tagatcttta cttgattaca atttacctgc tactgcatcc aacaattctt ggatcttagc
    29101 ttggttgctt cctcctgcca tggccatgtc tggtttacca ccaccacgtc catcgatgat
    29161 tggtgctaat tctttgacaa ggtttcctgc atgaaggtct tttgtcttgc ttgctacaag
    29221 gacattgact ttgtcaccga tagcggcaac taggacaaga agatcagagt agtctttttg
    29281 tttccagtta tctgcaaaag tacgaagggc accggcatcg gatacagaca cttgactagc
    29341 aatgtaacga tgaccgttga cttccttagc atctttgaag atatcgcctg cggctgcagc
    29401 tgcggctttt tctttcaact cagcattttc tttttgaagt tgacgaagtt gttcttgaag
    29461 tccttctacc ttgtgaggta cttccttgac ttgaggtgct ttcaaggttg ctgcgacagc
    29521 tttaagagca tcctcttgtt cacgataggc ttcaaaggct tccttaccag tcactgccaa
    29581 gatacggcga gttcctgaac cgattccttc ttctttgaca attttgaaga gaccaatctc
    29641 agaagtgttg ccaacatgag taccaccaca aagttcaata gagtagtcac cgatagtcac
    29701 gacacgaact tccttgccgt atttctcacc aaagagggcc atagctccca tttctttagc
    29761 agtgtcaata tctgtttcaa ctgtcttcac ttcaagtgct tcccaaattt tctcgttaac
    29821 ttgctgttca atcgcacgaa gttcctcagc agttactgct tggaagtggg taaagtcaaa
    29881 gcgaaggaat tcaacttcgt taagagatcc tgcctgtgtt gcgtggtttc caaggatatt
    29941 gtgaagggca gcgtgaagca aatgagtcgc agtgtggttt ttcatgacac ggtgacggcg
    30001 attgctatca attgccaagg tatattcttg gttcaaggca agcggtgcaa ggacttcaac
    30061 tgtatgaagg gcttgaccat ttggggcttt ctgaacattg gtcacagtag ccacaatctt
    30121 acctgactca tccaagattt gtccgtagtc agctacctgt ccacccattt cagcataaaa
    30181 tgacgtttcc gcaaagataa gagaggcagt tccttctgaa acagctccta cttctgcatt
    30241 gtcagcaacg atagctacca atttagaaga caattggcta gtattgtagt tgaagacact
    30301 ttctacagtg atgttttgaa gagtttcatt ttgcataccc attgagccac ccttgacagc
    30361 tgacgcacgc gcgcgttctt gctgttcttt catggctgct tcaaaacctt cacggtctac
    30421 agtcatacca gcttcttcag caatttcttc agtcaattca actgggaatc cgtatgtatc
    30481 atagagttta aagacatctt gaccagcaat gacagattga cctttttctt tcaagtctgc
    30541 cacaatgcct tgggcaaagt gttgacctga gtgaagggta cgggcaaatg attcttcttc
    30601 gctcttaacg attttctcaa taaagtcacg tttctcaagc acttctgggt agtagctttc
    30661 catgattttt ccaacagttg gaacaagttt gtaaaggaaa ggctcgttga tacccaattt
    30721 ttgaccatgc atagaagcac gacggagaag acgacgaaga acataaccac gaccttcatt
    30781 tcctggaagg gcaccatcac cgatagcaaa tgaaagagaa cgaatgtggt ctgcgataac
    30841 cttgaagctc atgttgtcgc catcttggtc ataaacctta ccagacaatt tctcgacttc
    30901 acggataatc ggcatgaaga ggtccgtttc aaagttggtc ttagcccctt ggataacagc
    30961 caccaaacgc tccaaaccag cgcccgtatc aatgttctta tgtggcaatt ccttgtattc
    31021 gctacgagga acagcagggt ctgcgttaaa ttgtgacaaa acgatgttcc agatttcaat
    31081 ataacggtcg ttttcaatat cttctgcaag caggcgaaga ccgatatttt ctgggtcaaa
    31141 ggcttcccca cggtcaaaga agatttctgt atctggtcca gaaggtcccg caccgatttc
    31201 ccagaagttg tcctcaattg gaatcaagtg acttgaatcc actcccactt caatccagcg
    31261 gttgtaagaa tctttatcgt ctggatagta ggtcatgtaa agtttttcag cagggaaatc
    31321 aaaccattca gggcttgtca aaagctcata agcccaagtg atagcttcgt cacggaagta
    31381 atccccgata gagaagttcc ccagcatttc aaacatggta tggtgacgcg cagtcttccc
    31441 tacgttttcg atgtcgttgg tacggatagc cttttgggca ttggtaatac gtggattttc
    31501 agggataatg gtcccgtcaa agtatttctt aagggttgct accccagagt tgatccacaa
    31561 aagagttggg tcatttacag gaaccaaact tactgatggt tctactgagt gagctttggt
    31621 cgcccagaaa tcaagccaca tttggcgtac ttgtgcacta gatagttgtt tcatattgtc
    31681 tccttattta cttgtttaat gtgattggct ttccagcatt tccacatagt caatcgcgac
    31741 acagagggaa atgactaggt ctgcataagc gtcctcaaga accgttacgg tataggtaga
    31801 ggtcagatgg aagagttcct tcttaatttc cgcaatcagc tgatcgcgat catccagcaa
    31861 tttgaaattc aaatcccaga tattgccctc gatacgaaga cctagattat caaactcata
    31921 cttatctcgc cagaaggtca acttcttacg aatgacaaaa ctcgagccat cccgaagctg
    31981 aatctcaaaa cgaggaagca aggtcaagat ttctttacta atctcactga cttgttcacc
    32041 agccgcatca tagatggtaa aggttttagg aatcttaaaa aatgatccct ccacctgata
    32101 ggcaatttct cccctgtcat ccttgatagc gaagcgttcg cctccaagac gaaacttttg
    32161 tttgacaaga aatgttttca tcaacacctc caaaaatcaa aagacaagct catatcacga
    32221 agggcgaaaa accgcggtac caccttcatt caatgaactt gtcattctct tgttcttatg
    32281 caattgtatg attgagtagc atgacttcct agcttagatg gctcgcagca ccgccatttc
    32341 tctggactaa gacaagtgaa aatcaattct caactttctt attataacgt ttttttaagc
    32401 ttgcgtcaac tggaaatgat ctccgttgaa ttagaccaat tccctacatc tctgattact
    32461 ttttcaggat atattttttc ttactgccgt ttttcttttt atcccaaatt ttcatattac
    32521 taaacacagc tactagaata tttccaaata taaaggtgcc tatcacccaa tatatggact
    32581 cagttgttag gtattgtcga tccaagccat cctttaaatg ggatagtata acagtttggt
    32641 taacaatcat aaaggttggc cagaaacttt ttttgaaaaa agtagacatt ttcattattt
    32701 gttgccgctt tctgtaaggt taatactcaa taaaaatcaa aaagcaaact aggaagctag
    32761 cctcaagctg tacttgagta cggcaaggca acgctgacgt ggtttgaaga atataggctt
    32821 agtatactac taggcaagca aataagcaac tagaatagaa aaagataggg ttctaaaaac
    32881 tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac gtttatctcc
    32941 tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt ccatttatgg
    33001 tcaaatttct cataaacttc taggtgtttc atggtttcaa catctggata gaaggcctta
    33061 tcttcctttg tttcctctgg gagcaattcc ttcgctggta ggtttggtgt tgaatagccg
    33121 acatactccg cattttggaa agcgttttca ggtttcaaca taaagttgat aaaggcatag
    33181 gctgagtctt ggtttttaac tgttttggga atgaccatat tgtcaaacca aagattgctg
    33241 gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg gctggcttca
    33301 ccagagaagg tcacgccgat tgcaacatta ttctgaatca tgtagccctt catctcgtcc
    33361 gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt ctcttccaac
    33421 tgctgcggat ccttggagtt gaggctgtag ccgagggaat tgagtcctag tcccagcacc
    33481 tcacgcgccc catcaaaaag catgatagaa ttcttatact ccagcttcca aaggtcatcc
    33541 caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa ggttccccag
    33601 aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa ctctggtccg
    33661 atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc ttcgtccttc
    33721 atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc accctgcttt
    33781 atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg aattcctgtt
    33841 tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt atagataacc
    33901 aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat tccccacaag
    33961 acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat gcttgctcct
    34021 ccttctcacg agagataaag taataaccta caactaggat aatactaaag agaaagacta
    34081 gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag taaatctcga
    34141 ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag tcatctaacg
    34201 aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa ggaagcatga
    34261 tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga atcatgtcgc
    34321 cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg gagaaggcca
    34381 cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta aagagaatca
    34441 agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg agtgatagaa
    34501 aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa gtcccgataa
    34561 tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa atcagcatga
    34621 gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta aagctattca
    34681 tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg tagaggacca
    34741 gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc tttccttagt
    34801 cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg aacccatacc
    34861 atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga taacgcggtt
    34921 cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga ccgactgaac
    34981 cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg tctcccactt
    35041 agtggcacca aggtcataac tagcattgat gagattatta tccatatcgt ctaagacatt
    35101 gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga taaaggaaaa
    35161 atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt ggttaataga
    35221 gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat tgagccaggt
    35281 aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca aaaagagggc
    35341 tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa gcactgagtt
    35401 gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat aattttctaa
    35461 actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca agggtgccaa
    35521 tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc ttgttttctt
    35581 catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg atttccacgt
    35641 attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg atgtggatgt
    35701 cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg gttgagtgga
    35761 tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact ccacggaaga
    35821 gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg cgcaagtcct
    35881 ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca accgcttcaa
    35941 agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc aagatgtttg
    36001 actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg tccacagggg
    36061 ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc atggcaagag
    36121 cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt tgtaattcac
    36181 gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa ggctcgtcca
    36241 acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc tgacgttgtc
    36301 ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc atcttgagaa
    36361 cttccgctac acgctgctcg atttctttct tatcaatttt acgcaagcga agtggaaagg
    36421 caacattttc aaacacattc atatgtggga acaaggcata ggattggaag acggtatgta
    36481 cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg atatctcctg
    36541 tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc gaaccagatg
    36601 cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct ttgagaacct
    36661 tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt ggttttttca
    36721 attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc aggtccccac
    36781 tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag gctttcaccc
    36841 cctttccatg acatagcagc agcttttcaa atacagcttc ctacttgctt tcacccaaga
    36901 tccggacttc tctttcaagc gtaatacctg agtgttcctt gactttttcg ataaccgatt
    36961 ggatcaagtc ctcgtagtct ttggccgttc catctgcgac attgatcata aatcctgcat
    37021 gcttttctga cacttctacg ccaccgatac gatagccttt caagccagct tctgaaatta
    37081 actgacctgc aaaatgcccg actggacgct taaagaccga gccacaagat gggtattcca
    37141 aaggttgctt gagttcacgt aggtgcgtca agcggtccat ttcctgcttg ataacctgat
    37201 gggttcctgg agctagggca aatttaactg acaagacaac tgcaccagac tcctgaatag
    37261 ctgaatggcg gtaaccaaaa gccaagtctt tagcagacag ggtttcgatt tctccatcct
    37321 tggtcaagac cttacaagac tgcaatatgt gagcaatctc gccaccatag gcacccgcat
    37381 tcataaagac agcaccgcca acgcttcctg gaataccaca agcaaactca aagccagtca
    37441 aactatgacg gagggcaatg cgagttgttt caatcaagtt agccccagct tctgcttcaa
    37501 tggtatagcc atcaacagaa acgttattga gcttgtcaca caagatgaca aatccacgaa
    37561 tcccaccatc acgaacgatg atattgcttg cattgccaag aaccatccaa gggatatttt
    37621 cttggttggc aaatttcaca aggcgagcca actcaaaacg atttcgtgga aagaccaaat
    37681 aatcagcctc tccacctact tttgtataac tatagctatg caagggttcc ttaaaacgga
    37741 tatcaattcc ttctaagatt tcaagcattt tttctcttac agacatgtca ctcttccttt
    37801 tacaaaattc attccattat accattttta gagacatttg acgaccataa aaataccttg
    37861 tttggatttt gcataagaaa aagaggttcc ccccttttta tgatttttta caaaagattt
    37921 ccttggttcc atagacaacc agaacgatct ccagtgctag aatcacttca accaagactg
    37981 gatttgtcaa ccagcctact tggaaaagag atggtgccag atcaaagaag gcatgcaagc
    38041 cataggctgc taggagataa atccatttct tctggcgaac agcttggtaa acccaaactg
    38101 tcaaaagtaa ttggaaacca agcgccaaga ttcgctcaaa accaagcaaa taaatctgcc
    38161 agaccgaaag tgactgaatg gtttttaaca tattttcaga cagtaattgc ataacctgtg
    38221 gattctgagt ttgaactgcc gaaagaacga tgtaaagatt gagtaaacta gtaaggccta
    38281 gaaaaatcaa ctccaagcca ccatgcccta ggccataggc caaggcatct gccttttcca
    38341 aacttctctt tttctccaac catttgaaga aaacaagacg agccgtttcc tcaaaaaatg
    38401 ctgccatggc taggccatag ataatataga taagcggatg atcttgcaag agggcaatac
    38461 taccgtcttt ttgaggatgc aaaatcaaga tatgcaccag tttttccaaa atctgcgaag
    38521 agacaaagaa agcgactgca cccaagccca agacagctag attaatctgg tatttctttt
    38581 tggcaaacca aatgcttcct atcagaaaag ctagcaacag caacatggta ataatgatat
    38641 gaatggtcat tttcttctcc tattctgcct tttcaatatc ttttttcatc tcgtcaacat
    38701 tgaacttagc aaacaagtat tgacggtctt ggactgggaa acgttggtcc aactggtcaa
    38761 ctgctcccac ctcgataatg ccttccttga tgacaaaatc catgacatgt ccaccgaagg
    38821 tcaaatcatc tgatatgaag tgcagatggt agcctgccac actgacccca tggaaaatct
    38881 caggcgtcca gaaaccaaca atagtccccg caacattgtc acgactatat tccggttgat
    38941 gggttgcgat atcagcaaac ttggtatcgg gtgttgactt aggaatcata cgcacatgca
    39001 tatgtgaaaa ttccccccga atcttgatag agcggaaaag attttcccca tcataataag
    39061 actcaattcg ttctttcaat tccttgtctg tcatctcaaa gcgctggcgg aaaatgacct
    39121 ctgcctgatg cggtaccact gcagcgtaag gaataagggc atctggtgac acttccacaa
    39181 tttctggctg gtctcctgac tctttggcct gataagcctt gccatccaag acaatcaatt
    39241 ccccatcaat ggaatccaag gttcccaaac caaggtcacc atgttctagc aattctccta
    39301 ctgtcatagt accaccataa aggccagcca tcaaggctcc aagagtattg tattgaaata
    39361 atttcactgg ttcctgcacg ttcttatcca ttcactttct tgtctgttat tctataaatc
    39421 ttactcctaa gtataccaca tttgccccta gatgtgaacg agagaaacgc tctagacatt
    39481 gccaagaagg aaaaaaaagg gtacaatgta acaaaatcaa gggaggtctg gaatgaagaa
    39541 acaaagcaag tacaaagagg tcgtttccta tctgaaaaat ggtatcgagt ctggacgatt
    39601 tccgacgggt agtcgcctgc cttctatccg tcaactgagc cttgactttc actgcagcaa
    39661 ggacaccatt caacgagccc tgctggaatt acggcacgaa caatacctct atgccaagcc
    39721 tcagagtggc tactatgtat tagaacaagg gcaacatcaa gacctagaaa tcgaggttac
    39781 cgacgaacat gccagtgcct atgacgattt ccgactctgt gtcaatgaaa ccttgattgg
    39841 ccgagaaaac tacctcttca actactatga caatcaagaa ggattagaag acctaagaca
    39901 atccattcac aaactcctct ttgaccaagc tctctactgc aaggctaacc aactagtact
    39961 gacttctgga acccaacaag ccttgtttat cctctctcaa atatcctttc ctagccaagc
    40021 caaggaaatc ttggtggaac agccaaccta ccatcggatg aatcgcctct tgattgcaca
    40081 ggggctggac tatcaaacga ttgaacgagg cattgatggg attgacttgg aggagctgga
    40141 aggccacttc aaaacaggaa aaattaagtt tttctacacc attcctcgat ttcactatcc
    40201 cctaggccat tcctattctg agcaggacaa acgagctatt cttgacttag cagccaaata
    40261 tagtgtttat atcgtcgaag acgactatct gggggatttg gactctaaaa agggccagac
    40321 cttccactat ctagatacag aggaacgcgt catttatatc aaatccttct caaccagcct
    40381 ctttccagcc ttgcggataa cagcactcat tcttccaaat actatcaaag aagccttcgt
    40441 ggcctacaaa aatatcctag actacgacag caacctcatc atgcaaaagg ccctgtcact
    40501 ctatattgac agtcaattgt ttgaaaaaaa tcgtttggct cgcttgacca atcatgaatc
    40561 ttaccaaaaa caaatcgagg aaaggataac taaaacacct tgtccccttc ctcattatcc
    40621 cctacacgat ggtttattgc tagacctgag acagtatcct aaaatcgcca gtctcaaaca
    40681 cagtcaactg ggcttggact tctttgaaga ggcctattta agcacctgtc cttatcaatt
    40741 tgccaaggtg tccctagaca atctggaaaa tgttttaaac tatttaaaag cagaattgga
    40801 atgacatcca actctgcttt ttcttattct tcaacttcag ttaaacttgc tgctttttca
    40861 agatagcttt ggtaagttcc ttcatcctta agtttttgga tgaccttgtc taccacttct
    40921 ttcaaatcat cactattttt tctaagagca acggcattgg cgtcgccgtc cttcatcttc
    40981 aagctgacag ttgcgacagc taagccagcg tttttagcag cataactaag tgcaacaggc
    41041 tcatccatat gaacagcatc tatttttcca gcctgcaatt cattgactgc ttcacccata
    41101 ttagttaggg aagttaattg agcttttggc aattgttcct tgaccattga ttctggaaca
    41161 gtcccttttt gggctgcaat attagcactt tctaggctag ttaaatcctt gtatttttcc
    41221 acatcagcct tacgaaccaa gaaactaatc ttgttttcat agtatgggat tgaaaaatca
    41281 aagacttctt ttctctcgtc agtagcacta attcctgcaa ctgctaggtc agccttacca
    41341 gtttgaagac tggtcaaaac attgtcaaaa ctcatgctta agatttccaa cttaacccca
    41401 agttcatcag cgatagcctg agccatgtcg atgtctgcac cgactacctg gttctttcca
    41461 ttaaccaatg attgaaattc aaagggtgca tagtcaggac tggttgccac aactaatttc
    41521 cctttttgtt tgatagcatc cacagcagac tgagaaccat tagaacctga ctggcaagct
    41581 actaagaaga aacttgcaag aaaattacat aaaacaaata tccatttttt tgatttcata
    41641 aataaacaac ctctctgtta attttgtata attataacga tatccaagtt acttgtcaag
    41701 tgttttttaa atttttatct caaaaatatt ttttcgttca aaaaaaggag ccatcagttg
    41761 atttcaagct cctttttata cagaattaaa ctattttata gttcgacaat cttacctgtt
    41821 tcaaagtaga caacccattc acagatattt ttagcatagt caccgatacg ctccaagtag
    41881 gaaataactt ggaaataatc acgacccgta acaatggctt ctggattttt cttaatctct
    41941 tcagtcgcaa ggtcacggat agtttcaaaa tagtggttaa tttgctcatc catggaggcc
    42001 acccggtatg cgtcgtcaac agaaccatta agataaagat caagtgctgc ttcaacaacg
    42061 cttttaactt cacgtcccat ttttttaatt tcttcctcta cagctggaat gcgctcttcc
    42121 cccttcatac ggatggttgc ctgggcaatg gctacagcgt gatcccccat acgctccaca
    42181 tctgatacag ccttaaggac agtcaagact gtacgcaaat cttgagagac tggttgttgg
    42241 agtgcgatca tttcaaatga tttcttttcc agtttcactt cgtattcatt tacttctgca
    42301 tcatcttcga tgacctcttt tgccaggtca cggtcatgcg tgacaaaagc acgtaccgta
    42361 cgattgattt gtgagagcac ttcttgtccc atagcgtaga actggttatg taatttctct
    42421 aaatcttctt caaattgaga tcgtaacatc tttcatctcc ttatccaaat tttcctgtaa
    42481 tatagtcttc cgtttccttg tgttggggat caaggaacat ctgcttggta tcattaaatt
    42541 caatcaaatc tccatctagg aaaaatcctg tcttatcaga gatacgtgaa gcttgctgca
    42601 tggaacgggt taccagaagc atggtgtact tgtcttttag accatacaag gtttcctcaa
    42661 ttttaccagc tgaaatcgga tccaaagccg aagttggctc atccaagagg atgattttag
    42721 gactagttgc caagacacgg gccacgcaga cacgctgctg ttgaccacct gacaatccaa
    42781 tagctgaatc atatagacga tccttgacct catcccagat agaggcacct tgcaaggctt
    42841 tttctacggc ttcatccaga acctgcttat ccttaattcc attgatacga agcccgtaga
    42901 caacattctc atagatagtc atagggaaag gattaggttg ttggaaaacc attccgattt
    42961 ccttacgtaa ttcaaccgta tctgtacgcg gactgtagat gttgtggcca ttgtacacca
    43021 cggatccagt tgtggtcacc tctggattga gatctcccat gcggttgaga gacttgagga
    43081 gggttgactt ccctgatcca gatggaccaa tcaaggctgt aatttcctta ggttggaaag
    43141 atagggaaac actattcaaa gccttctttt tattataata aacggacagg tctgatacct
    43201 gtaaaatcgc atctgtcata cggtttcctt tctaaccaaa gtgaccagat acatagtcat
    43261 tggtggactg tagcttggca ttttggaaaa tagttgcagt cttgtcatac tcaatcaaat
    43321 cacccaagta aaagaagcct gtatagtcac ttgcacgagc agcctgctgc atattatgcg
    43381 ttacaatgat gatggtaaag tttttcttga gctcaaacat ggtctcttct agttgcatgg
    43441 tcgcaatcgg atccaaggct gaggctggct catccattaa gaggatatct ggcttaacag
    43501 agatggcacg agcgatacag agacgttgtt gctgaccacc tgataaggtc aaggctgact
    43561 tgtggagatc gtctttaacc tgatcccaga gggcagcctg acgaagggag gtttctacga
    43621 tttcatctag gacttgctta tccttaactc cagcacgttc atgcgcaaag gtaatattac
    43681 ggtaaattga cttagcaaat ggattggggc gttgaaaaac cattccaatg tgtttacgca
    43741 tttcataaac gttgatttct ggacggttga catcaattcc acgatagaga atctgcccag
    43801 ttactttagc aatatcaata gtatcattca tgcgattgag actgcgtaag taggtagatt
    43861 tccccgatcc cgacgggcca atcaaagctg taattttatt tctttcaaat tgcatatcaa
    43921 tccccttaat ggattcattt ttaccatagt aaacatggac atccttagta gaaagggcta
    43981 ctttttcttc aggaaaggta aggatatgct tctcatccca gttatatgtt gacatggctt
    44041 ctcctttagg cagcggttaa tttcttgtgt agatagcttc cgaacttacg agctccaaag
    44101 ttaaaaatca ggataaagat caggagcaca gcggcagaac ctgctgatac aattgttcca
    44161 tctggaatag tgccttcact attgactttc cagatatgga cagccaaggt ttctgcttga
    44221 cggaagatag agatggggct agtcacactg aggatattcc agttagacca gtcaagagct
    44281 ggcgccgatt gccctgctgt atagatcaga gctgcagctt cgccaaagat acgaccagat
    44341 gccaagacga cacccgttac aatacctgga agcgcttctg gaataacaac atgaaccact
    44401 gtctcccagc gagaaatccc aagagccaga ccagcctcac gttgggtatg gtgaacgtgt
    44461 ttcaaactat cttctacatt acgcgtcatc tgaggcaagt taaagactgt caaggccaag
    44521 gcacctgaaa tgattgaaaa tccatactca aactggacta caaagatcaa gtaaccaaag
    44581 agacccacca ccactgatgg taaagaggac aagatttcaa tacaagtccg cacaaagttg
    44641 gtaacaggac cttttttagc atattcagcc aagtaaatcc cagctcccat agaaagaggt
    44701 acagaaataa tcaaggtaat gaccaatagg aaaaaggaat tgtaaagctg aatgccaatc
    44761 ccaccacctg cttgaaaagc agaagacctt ccagtcaaga aagaccaaga gatatggggc
    44821 aagccccgaa ccaagatata gagaatcaag gaagccaaga ttgtcacaat gatgctagca
    44881 atcgtataga ggacagctgt tgcaagttta tctaattttt tagcgcgcat aatttttctt
    44941 ccctctttct ttcgtaatca atttaatcac actgttaaaa actaaactca tcaagagcag
    45001 taccaaggcc agtgaccaga gaacattatt atttacagtt cccatgacag tgttcccaat
    45061 tcccatagtt aatatagaag ttaaagttgc agctggtgtg gtcaaggaag ttgggataac
    45121 agctgagttt ccgacaacca tctggatagc taaagcctca ccaaaggcac gcgccatccc
    45181 aaagaccact gcagtgaaaa taccagaacg ggccgccttc aagattacac gccagatagt
    45241 ctgccagcga gtggctccca tagcgaaact ggcctcacga taataacgag gaaccgcacg
    45301 caagctatcc gttgtcataa aggttacggt cggcaaaatc atgacaaaga ggacggaaat
    45361 ccctgacaaa atcccaaaac cagtcccacc aaagacactg cgaacaaagg gaacgacgac
    45421 ttgcaagcca ataaatccgt acactactga aggaatccca accaggagtt caatagctgg
    45481 ttgtaaaatc ttcgcccctt ttggtgatac ttcggtcata aaaactgctg caccaatagc
    45541 aaagggtgtt gcgataaggg ctgagagaat ggtaacgata aaggaaccca aaatcatagg
    45601 aagggcacca aattctttac tagaaggatt ccaagttcct cccaaaagaa agtcaaagat
    45661 attcacacca ttgacaaaga aggtcgacaa gcctttttgc gctacgaaaa ccaaaatcat
    45721 ggccacaagg atgactatca aagaaagaca ggcaaaggtc aaaccttttc ctaatttctc
    45781 cagacgagaa ttctttgatg gaagcaacat tttcttagct aattcttctt gattcattat
    45841 tgtctccctt ccaacactgt cacagttccg gcagcatctt tttcaacctt catttcctta
    45901 atcggaatat acttcaatcc tttgacaatc ccttcttggg tctcatccga gagaacaaaa
    45961 ttgagaaatt ctgcagctaa ctcattgggc tgccccaatg tatacatatg ctcataagac
    46021 cacaagggcc aattattgct acttatattt tctggactta agtcatagcc attcaacttc
    46081 atgcttttga ccgaatcatc tatataggta agagataaat aagagatagc tcctggactt
    46141 tttgatacga ttgattttac cgctccattt gaatcctgct cctgactttg catggcagac
    46201 tgaccttcca taatgacagt atcaaaggta gcacgagagc cagagccggc tgcccgattg
    46261 ataacagaga tgggtaagtc cttaccacca acctctttcc aattggttac ctcacctatg
    46321 aagatttgac gaagttgctc tgtcgttagg ttatcaacat caacctcctt attgacaatc
    46381 agagccaagc cagctaccgc gaccttgtgg tcaacaagag cagaagcatc aattccgtct
    46441 ttttcctcag caaatacatc tgagtttcct atatcaactg ccccagactg aacctgggac
    46501 aagcctgtac cagaacctcc cccttggaca ttgaccgttt ttccaacatg gatcgtgcca
    46561 aattcatctg ccgctacttc aaccaagggt tgcaaggcag ttgagccaac agccgttatg
    46621 gattctccac gatcaatcca gctagcacag cctactaaac aagccgtcag ccaaaaagcg
    46681 ataagagaca gagcaagctt ttttcttttt ttcactgttt ttctcctcga aaataattat
    46741 gaatactgtg aattttttaa gtagttcttt atgagttgac gcatgaattc ttaccaaatt
    46801 tctgcgcaat tgattattta tataatatag gctatattac tctttcctaa cctccttttt
    46861 tcatatgtgg ataaaatctc ttgtctatcc cttcccccat tgtcacccat tatagtcatt
    46921 tcgtgtctct ttttcccctt tttaatgcaa gggaaattac tctccttaga tgataatcta
    46981 aaagctagaa aggtatctca aatctctcta ctctcccaga ctagtttaca actaaaagga
    47041 aaagattcta ttttatgaga aatctagttt acaagcggta agaacgctaa taactaaact
    47101 tcttgtactc tttgaaaatc tcttcaaagc agtgttttga gctatctatg gctagcttcc
    47161 tagtttgctc tttgattttc atcgagtagt aaaactacat gtgatggcaa tcaagatatc
    47221 aagaatcatc ctactaaaaa aatccatact ttcactataa catagaataa gatatttgac
    47281 tagcattttc atttgaatct gaggcctttt ggaaaataat ttttcaaaac atttccagta
    47341 acctttgcaa agcccaagcc attgccttta accaaaactt ggtaccaacc atttggcaga
    47401 ctttctgcca gctgaacggt ttctccagcc gcatacttga caaactcttc ttggccaatt
    47461 tcaaccgact gttcgacctg actcggtttc aaggctaaac caagagcgaa actgggctca
    47521 aagcgtttct tcttaaaagt acccagatgc agtccattgc gagcaatctt gagcttccct
    47581 aaatctggca aaagttctgg caagagataa agctggtctc caaaaatctg caagataccc
    47641 ggtagattga ccttcaaatg gttttgggca aattcctgcc acaaggcaac ttgttcacgg
    47701 ctgaggttac tcttacttgc cttaaattta ggagctggat tgttaccctt aaactgtaga
    47761 tgggcaacaa actgaccctc tcccttaaac tgatgagggt acatccgagc cgtttctggc
    47821 aggtcaatac cagctaccat tccattgata tgctctactg gcaacaagtc aaaatcatac
    47881 tcttccagca accaattgac aatctcttcg ttttcctcgg gtgcccaggt acaggtcgaa
    47941 taaaccagac gaccaccttc agctaacatg gtcactgcat cctccagaat ttctctttgc
    48001 aagctagcac attgactcgg ataatctaag ctccaatagt ccatagcatc aggttgctta
    48061 cgaaacattc cttcaccaga gcaaggggca tcaagaacga ttaagtcaaa atagccttta
    48121 aagaccttga ccaagcggtc ggcagattca ttggtcacca cgacatttgt cgctccaaaa
    48181 cgctccatgt tttcaaccaa aatcttagcc cgtttgcttg aaatttcatt ggaaacaagt
    48241 agcccctccc ctgctagata ggctgccagt tgagttgatt tgccccccgg tgcagcagcc
    48301 aagtccaaga ccttcatacc aggactgggt tgggctactt gagccaccat ttgagcagca
    48361 ggttcttgcg aataaactaa acctgtagca tgctcaggcg atttccctga aaccttccca
    48421 tagtggcccc aaggggtttg agtaatggca tcagaaaagg aaagttgctc ttcttttaag
    48481 ggattgaccc gaaaggccga aaccgcttcc tcctcaaaag aggcaagaaa atctcttgcc
    48541 tcatctccta gtatttcttt atatttttca acaaatcctt ctggaaattt catttaagtt
    48601 cttttccttt cgtaaatata ggactgaatt tcctcctgca tctcaagagg caccatcatg
    48661 accggctgtc tggtttgaaa atcaggagct tcaccaaaaa gggtcacaac ccgatagccc
    48721 agactttccc ctaaaatact agctgcggca taatcccatg gttgcagata ggtgagatag
    48781 gtcaacaaac gccctgacaa aatcttggca aaactaatgg ccgcacttcc atagacacga
    48841 acaccaagaa ccgctcggct caaatcagcc agcccccatt cattggtttc cagcatacca
    48901 ctattccctg caatgagaaa atctccaagt ggtttagttt taaaagaagc taggggccta
    48961 tcatttagac aaactggaaa ttccccacca ccgtggtaac aatccccttt gaccacatca
    49021 taaatcagac caaactgtcc ctgaccattt tcaaaataag ccatcataac agcaaaatct
    49081 tcctgctggg ctacaaaatt attggtacca tcaatgggat caatgaccca aaccttgccc
    49141 tcttgaaccg aggctcgcag acaaccttct tcagcacaaa tcttatcctc aggataacgg
    49201 gacaaaatct caccaaccaa gagttcctga acttctttgt ccagtctggt caccaaatct
    49261 gttggagagg acttggtttc aacacgcaag tcttcctgca tatggtcaag aatgtactga
    49321 cctgctttct taacaagctc tttagcaaat tcaaatttac tttccaagag aaatctttcc
    49381 ttcccctttt tctttggcag cctgaactgc tcggtaaagt gaatagccac taaccgtttc
    49441 aaattctcgt cccaaacgtt tctcttcgct cttgcttggc acgaccgctt tgaatccctt
    49501 ataggagtcc agtaactttt tagcctctac tttgccttca taggcagctt caacatcatt
    49561 aaaaaaagaa agcactgaag caagttcttc agtgctccac gacaaatcta gtgggtaact
    49621 atactgtttg ttcattaact aataccagct ctcattcttg cttcttttag ttcttgctta
    49681 cgataactac gagggagaaa agcacgaatc tcatcttcat taaaaccgat ttgcatacgc
    49741 ttggcatcaa taataattgg acgacgcaaa agactaggat actgctcaat caaatgaagc
    49801 aattccgata ccgaaatact ctctacatca atattcaatt tttgaaaaat ttttgaacga
    49861 gttgaaatga tgtcatcagt accattttcg gtcaaggaaa ggatgtgttg caattctttt
    49921 cttgttaaag gactggtcat aatattgtgt tccacaaagg gaaccttatg tttttctaac
    49981 caggccttag ccttacgaca tgatgtacag ctcggtgata gaaatagtgt aatcatgctt
    50041 ttctcttctt atctatactt tgctacttct attatacaaa aaaataaagc gcttgactag
    50101 ggatttttag aaaaaaaagc ctatttttca agaaaaatag gctttttgcg aacgattgac
    50161 acaattggat ttggttaatt cactcttaac gatggtttta aacgatatat atttttatat
    50221 atgcaaatta aaaacatctt tcatttcatt tcctacgact tttcagacac agatagccaa
    50281 agaagctttc atagagggca aaaaagagga ggaaggcatg aagaaagaag gtctctggca
    50341 aaatcataat aacaggatcc ttggctggat caaaaagcca ggtatcatct cccacaaaga
    50401 gaatttgatg gaaaagagta aagaattggt caaaaccaat caaaactccc ccaagtccaa
    50461 tcatcacagg taagactact agagtcagga gactttttcg ataaagagac aaaaagtcct
    50521 ttttcacaat tctattgaca aagacataga aacttggcag tgtcactaga gctactagct
    50581 gaaccaaatg aaagagattc ttgaccactg cgaaatggtg cagaccagct gctgacgaac
    50641 gaaaatcagg catctgtaag acctgactaa aaggattggt cagataattc atcaagatat
    50701 gaaaattgta ttgaatggtt tctggtttta gatagactcg attcgttaag tttagccact
    50761 gaatctccat aggatagaaa atccaagcca gataaatggt cagaaggatt gagagggaga
    50821 ggagaaagag catagagccc caaaagatca atttagtttt catcaaaatc ccactccgca
    50881 aggctagaaa ccacatgtgt cggtgcgatt ggcaggccag ctacttcttc tgccttagta
    50941 aaacctgtcg tcaccaagag cgttggaatg ccattgtcaa tcccagcccg gatatcagtc
    51001 aaataattgt ccccaaccat aattaactct tcacgttcca aacctaagtg ctcaaccgcc
    51061 ttgtccataa tgatggcatt gggttttccg atataaaccg gcttcactcg tgtcgctact
    51121 tcaagcagcg taatcaggga gccagcacct ggcaaaagac cacgttccgt cgggatgttg
    51181 aggtcaggat tggttccgat aaaatgggca cccttttgaa tagcaagagt tgctgtggca
    51241 aatttttcat agtcgacttg ccaatccaga ccaactacca cgtaggcagg gttttccttg
    51301 tcttccacat aaccagccgc cttgatggct tccttgagtc ctgcttctcc gacgacatag
    51361 acggtctttt caagccccaa atcattcata tagtcgatgg ttgccaaagt cgctgtgtag
    51421 acagtcgata ggggcgtatc gatattaaaa ttctgagcca acatctcctt aacactctct
    51481 ggagtgcgag ttgtattgtt ggttacaaag agatagggaa tgtcccgctt ttgcaattca
    51541 tgaacaaaag tctctccagc agggattcgg tctttcccct tataaatggt tccgtctaaa
    51601 tcaattaaat agcctttata tttcatctat ttctccctaa gcctttttta tttctttcca
    51661 agtaatgatt gcttgggcat tgataacccc atcacttgta atttcatgct tgctttccag
    51721 tccagtccgt tcaacagccg atgtaatcac cccacctggt cgaacttcct tgacatactt
    51781 gaggttgatt ttcttgggaa tatagtgggt caaaaaatcc gctcccatga cctcaaaaat
    51841 ccagtccaag tatttactgt tattgacatg accattcata tccaagtcgt aaaaacgaac
    51901 atggtaatcc ttgctgatcg gctcttccaa ggactcatac ttcggtccac ggataagttt
    51961 tttatcaaaa tcagactggt aaggagccac aatctcaggt tcaacagcat ggacttttcg
    52021 actgtcgcgg tccatgagaa caaaggtcgc catcatatgg atgagctcct gccccgcttc
    52081 attataaata gtaaagcgac ggtagcaaaa aagtcgattg tagctcaagg cttccgtttc
    52141 gatggtaatt tcttccgcaa aacgaggcaa acgaaccacc tcaatatcat attctgcgat
    52201 aatccagacc agattatagt cttccaaaat ggccttatca ctaactccca gttcaatcga
    52261 ctgcatccct gaaacttgca gtgacagcaa aatcacatct ggaagtttga tatgaccgtt
    52321 catatcagcc atatcaaaag gaattttcat tttcatttga taagttaagc ccatgatcct
    52381 actccaaaat aaatcgttct gctacagtat ctcccaaaaa gagacctctc tttgtcatgc
    52441 gaacgtggtc accctcaatc tgcatgaggc cttgttgaac caaatctctg acaatttctc
    52501 cataaagtcc agcaaaagac tgtccaaatt tttcctcaaa tcgcgccatg gaaaccccgg
    52561 atttcttgcg gagtcccaag aacatttctt cttccatttg ctccttttga ctcaggtgat
    52621 cttctgtaat acaagcattg ccttcctcaa ccgcactgag ataatgacga atgggaccat
    52681 gatttttata acgtactcca ttgacataac cagatgcccc tgcaccaata ccatagtatt
    52741 cagcattgtc ccagtacatg agattatgac gactttcaaa gccgggtttg gagaaattag
    52801 aaatctcata atgctcaaaa cccgctcgct ccagctctgc aatgatgtac tcaaacatct
    52861 ccgcttctag ttcctcctta ggcagaggca atttcccacg tcgcatccgg ttcataaaga
    52921 ccgtatggtt ttctaaaatc aaactataca aactcatgtg gggaatatcc agtccaatgg
    52981 ctttagccac attttccttt acttgctcca tggtctgacc aggcagagca taaatcaaat
    53041 caatggagat gttgtcaaaa ccagccagtt tcaggcgatc gatattttca taaatatcct
    53101 tctccaaatg actgcgccca atctttttca acatcttatc atcaaaggtc tggacaccta
    53161 gcgaaacacg attgacagcc gaatttttca aaacagctat cttatccgca tccaaatcgc
    53221 ctggattggc ttcaatggtc aactcttcca agacagacaa gtccaagttt ttagtcaagc
    53281 cattcagtaa aacctccagt tgcggagccg acagggctgt cggtgttcca ccaccgatat
    53341 aaagggttga caacttttca atatcataag aacgaaactc ttccagcaga tgctctaaat
    53401 agctgtcgac tggctgattt ttgatgaaga cctttgaaaa atcacaataa taacaaatct
    53461 gggtacaaaa tgggatgtgc acataggctg acgttggttt tttctgcata gtaattatta
    53521 taccacaaag actagattcc agataaaaat caccatcccc agatacatag tccgtccgga
    53581 gatggtgatg gtttattctt ctgttatatc aatcacaatc tcttctgagt catcaagagc
    53641 ttcggctttt tcttgccatt gctccttgag attatttaat tgattttttg atgcttctgt
    53701 cgcttgaaga gcataggatt tagcttgagc aagtatactg tccacagtga tttcacctga
    53761 ctcaacctgt tcttttgttt tcagaacaaa atctgtagcc tgctccttaa cttctgtcag
    53821 tttttcacag acttgctcct tggcatactc cggatcttct ctcaaatcat ctagaaaatc
    53881 ttgagcctga ctgcaaactt gtttgccctt atcacttgtt aaaaacaagg caagagctgc
    53941 acctgaaacg gttcctaaaa ggattgagga taatttaccc ataaggattc tcctttttta
    54001 ttttttgaaa aatttacttg caagacgaag agctgacaga cttgcaccag tcttgagtgt
    54061 ttttgaacca gctgatgaag ctttcttgct caagacacgc gcatggtcat tgaggtctga
    54121 aacagataga gataaatctg caacagcact gaagagtgga tcaatcgtag ccaccttgac
    54181 attgatatca tctgccaaga cattgacctt agccaacaac tcattggtgt gatgcaaggt
    54241 cacatccaca tctgaagtca aggttttaat cgtcttttct gtttcatcga tgacacgacc
    54301 aagcttttgt acagtaatga tcagatagac caaaaagaca atcaaagcta gggcaacaag
    54361 aatatatgca acttctaaca tttagttttc ctcctctgta atatagtaag gggccttctt
    54421 tcgattttga taaataacga tcattatacc gagaccgata aggacaactg acagccattg
    54481 ggacactcga aggccgaaga acatgagact atctgttcgc ataccttcga tgaccatacg
    54541 accgaaacca taccaaatca agtaaaaggc cgtgatatga cctcgtctga gactcttcca
    54601 tttccgtcta aaaatcagaa tcaaggcaaa gccaagcaga ttccatagag actcataaag
    54661 gaaagtcggt tgacggtagc tcccctcaat atacatctgg tcacggataa agccaggtag
    54721 ataatccaga ttatccactg ttgcaccata agcttcttgg ttaaagaaat taccccaacg
    54781 ccccaaactt tgagcaatca taacgctagg cgccgcaata tctagaaaat cccaagtatt
    54841 gatgagttta cggtcagcaa agatatagag cacaagagcc ccagttatca aaccaccgta
    54901 aatggccaaa ccaccattcc aaatggcaaa aatctctcct aaattctgac tatagtaatc
    54961 aaatcggaaa ataacatagt agagacgagc tcctaaaata gccaagggaa aagctactaa
    55021 gataaaatct aaaatatcgt ctggtatgat cttctttcta ggtgcttctt tcatggtcaa
    55081 ataaaccgca agaatcaagc ctgtcacaat acataaggca taccaacgaa tggctagggg
    55141 tcctagttga atagcaattg gatcaagcat tttgcacctc atttcgagcg atgagacttg
    55201 tcagtcgttc gtcgaacaaa cgggtcgcat caaagcccat ttccttggca cgataattca
    55261 tggcagctgc ctcaatcaca acagagatat tacgacctgt tttaactgga atacgaatac
    55321 gaggaatggc tacgccagaa acttcaagtt cctctgcatt gtttccaaga cgatcaaagg
    55381 tcttatgcgt atcgtaattt tccaaataga cagcaagctg aacctgtgaa gaatccttga
    55441 cagcactcgc accgtagaga ctcataacat cgataatacc aaccccacga atttcaatca
    55501 agtgtttcaa aatttcagct ggttcacccc agagagtaat ctcatccttg gcaaagatat
    55561 cgacacggtc atcggctacc aaacggtgac cacgtttgac aagctcaaga cctgtctcgc
    55621 tcttaccaat tccactatct ccctgaatca agacgcccat cccataaata tccatcaaga
    55681 caccgtgcac actggtacgt tctgccaaac gagaatccag atagctagat aactctccag
    55741 ataaacgact ggtagctgca cggctggtta aaatagcaat cttacattct ctagcagcct
    55801 ttaacatctc ctctggaacc accaaaccac gggcaacaat gactgctggt gtctcaggta
    55861 gaaacatttt tttcaaaact tcataacggc tgttggaagg catgctgatc agataagacc
    55921 actccttcat ccccaaaagt tgaatccgct ctggtgtata gtagtcaaaa tagcctgtca
    55981 tttcaagacc aggtcgcgta atatccgctg tattgatttc cttttcaagc aattttggtt
    56041 caccatagac aatgtctagt ctaagctttt caatcacttc ttttactaaa accgacatca
    56101 tttcctcctt caaatgagtt cttctctcta ttatatcaaa ttgtaggagg aagtttcaga
    56161 tttttgcagg ctttggagta tttatttaaa agaaaaagga ctagatttct ctagcctttc
    56221 attccaatta gaatttttta cgtttacgag ctacttctga tttacgttta cgttttacag
    56281 aaggtttttc atagaattca cgtttgcgtg tttcttgaag agtaccagct ttagtaaccg
    56341 cacgtttgaa acggcgaagt gcgtcgtcaa gagattcatt cttacgtact actgttttag
    56401 acattttttt cactcccttc aagttcaata tctatttcat tctacacgta aaaggaataa
    56461 ttgtcaagca aaaatgcggt ttaattttga ttttttcttc catttataca agagttgaaa
    56521 gcgttcaata gaacattgct tttttatttt tcgagtaagc taagcgcttc agcatctgcg
    56581 atgatggtta catcagggtg attttggagg ctacttgcag gtaggttctc agtcactggg
    56641 ccagatactg ttccggcaat ggcttctgct ttcgactcac cgtaagcaaa aagaataata
    56701 gacttggcat ccaaaatgtt tttaatcccc attgaaatag cttgggttgg gacgtcttca
    56761 atcttggcaa agaagcgtgc attggcttcg atagtagact ggtcaagttc tactagatgc
    56821 gtttgactgt caaatggagt accaggctca ttaaagccga tatgcccatt gcgaccgatt
    56881 cccaagattt ggaggtcaac tggatggtca gccaaaattt ggttgtagcg ttcaacttca
    56941 gcttcagcat tgtccttaac accacgaggc aagaaacttt ctttaaatgg tttttggttg
    57001 aacaagtttt cttgcatgaa gtaacgataa gactgtggat tgtccccatc aaggcccaca
    57061 tactcatcaa ggttgacact ggttagattt gaaaaatcaa ggtcactctc aacaatttcc
    57121 ttgtaaaatt caagtgggct acttcctgtc gcaagtccta gagtttgagc tccattagcc
    57181 aatttttcct tcaaaatctc aaaagcaact tttccacctt gaacttggtt ttcaacttta
    57241 ataactttca tcttttcatc ctccatttct gtctatattt attatatggt atagaccaat
    57301 ttttgtcaag tgaaaacgat ttaatttcta aaaaaagagc gtccaaactt gaaacgtgtt
    57361 ataatggata ggattagaac ttagaaagaa tgaacagata tatgaataca gctgattttg
    57421 atttccactt gccagaggaa ttgattgccc aaacgcccct tgaaaaacgt gatgcctcca
    57481 aactcctcat cgtcaaccgt gagacaggag aaatgcaaga taaacacttc cactctatta
    57541 ttaatatgct ggaacctggt gatgcccttg tcatgaacga cacccgagtt ctccctgccc
    57601 gcctctatgg tcaaaaagtg gagacaggag gtcatgtgga acttctcctc cttaagaaca
    57661 ctagtggaga cgagtgggaa gttctggcta aacctgccaa acgcctcaag gtcggtactc
    57721 gtatcagctt tggtgatggc cgcctcagcg ctgtcgttac agaagaattg acccacgggg
    57781 gacgcattgt ccgctttgaa taccaaggaa ttttcctaga agtcttggaa agtctgggag
    57841 aaatgcctct gccaccttat atccacgaaa aattagatga ccgtgaacgt tatcaaaccg
    57901 tctacgccaa ggaaagcggc tctgctgcag caccgactgc tggtcttcac ttcaccaaag
    57961 aactgctggc agaaatccaa gctaagggtg ttcatctagt ctatctgact ctccatgtcg
    58021 gactcggaac ctttagacct gtttctgtgg ataatctgga cgaacacgaa atgcactcag
    58081 agttctatca actttctgag gaagctgctg ccacccttcg ctctgtcaaa aaaaatggtg
    58141 gtcgtgtcat cgctgtcgga accacttcta tccgcacctt ggaaactatt ggttccaagt
    58201 ttgatgggca aatccaagca gattctggtt ggaccaatat ctttatcaaa cctgggtatg
    58261 agtggaaggt cgtggatgcc ttctcaacca acttccacct gccaaaatca actctggtca
    58321 tgttggtttc tgcctttgca ggccgtgaat tagtcttaga tgcctaccac cattccatcc
    58381 aagaacacta ccgcttcttc agttttggtg acgccatgtt tatttattga gaaagaattt
    58441 ctctaaatct tctaatacca ataaatcgct aagatattat ttcaaagaac atctacaatt
    58501 gaaactctag ctagctgtag aagaggtcta gtacattgaa attaaaatgc ttccccctag
    58561 cttcgaaaat attgccatag attgcgttga ctctccaaat tgattcatct atattttatt
    58621 tcagcttcct atactttctt cgctgtttgt aaatcaaaat gcaagacaca tgagtagcac
    58681 catatttgtt actcttatct gtcctctcaa gagactatta tgagttattt cagaatcatt
    58741 cactactttg accctgactc tccttagtct caaaatcaaa gacttatact cttcaaaaat
    58801 ctcttcaaac cgcgtcaacg tcaccttgga ttatatatgt gactgacttt gtcagttcta
    58861 tctacaacct caaagcagta ctttgagcaa cctgcgacta gttttctagt ttgctctttg
    58921 attttcattg agtattaaac aaaaagtgaa caaagctgaa ttctaatgta cagaagacta
    58981 ggcttgttca cttttttata gtcgctataa gatgacctta tctatagctt tttatatata
    59041 attatatatt cagacatact attatcaatt ttgtctcagg gaggaatctg ttaacgcacc
    59101 cattcaccat tatcattgac tctatagcca tctatacttg tattgaccgc taactcaccc
    59161 gatgcattta cataatacca tttaccacca acttggaacc attgattaac tttcatagaa
    59221 ccgttgctgt tgaggtagta ccatgaacca ttaacttgta cccaacctgt tgccatggaa
    59281 ccatcagtat tataaaaata ccacatacca ttttcttgtt tccagcctgt tgttggagca
    59341 actgctttag ctggttctac tgctacatct gttccttggt tagatgtaac agatacagga
    59401 tacgaaggaa tagatgattg ctcaggaaca acaacttttt caggttctct cgtccctctc
    59461 cttatacgtc tttttaccat ctctttagta atttgacgag aagtagtttc ttcaattgtt
    59521 ccatcacgtt catctacagc atagattgta gtaagagtaa ttttaccaat ttctcctact
    59581 tcttgacctt tatcaagagt tgggtcatcg agatattctg tttcgattgg aatttcttgg
    59641 acaagaactt ggggcttggt tcctttttta acaactcttg tttgagagtc ttctttttga
    59701 cttaaagtac tctcagttac ttgtccactc tttccatcta catcataagt tatcgttgta
    59761 actgttttcc cattctttcc tagagtaatc tcttgctcct gtcctgcaga aaggtcattg
    59821 tctgcttcat atttagtagc acatggaaca agaacttctt caaccttgct tttagctgga
    59881 actttgataa ctgtatccgt ggcttctttt ctatcaacag taacctgttc ggtaacatga
    59941 ccagtctctg gattaacatc gtaggtcctt gtcgtagtta catagccatc ctctccatca
    60001 attgtaacag gattttcact acggtctttt gtttcatctt tttcataacg aattcgcgta
    60061 cttgaaattt tcttggttac taccttaggt ttagtcgcta cttttacaat aatatcccca
    60121 ttgtcagcgt catcatactc tattccctct tctttatctc tagtatcatc tctgacatat
    60181 tgaatcccat cagcagcatg aacaaaactt gtattcagat tcctcctaaa aataaagtta
    60241 gcccgattac cgcagaacca aaaatctttc cgagtttacg taatgcatag cgcttattgg
    60301 tattagattt tgccattaca tcctacttct aaaagttact acttctagta tagcatcttt
    60361 tctatcaaac gttaaacagt atactttata tatcaaatat acttagaatg atatattgat
    60421 tattgaacta acgctttaac tatatcgtaa tcaatctcat atataaagga ttgcagacat
    60481 cttatctaaa tacatgctaa tatatttaga tacaaacatt ccaacttgat aactttcact
    60541 catctttcat cattccttat acaactatgc agtataaata gaatagtttt ctcatcagaa
    60601 tgagactatt ttaatattag atattttgat agaaaaaaca tgaataaaat tggttgaatt
    60661 taattcccta actcgataga ggattctatt ttaaatttaa caacagctag gattacacta
    60721 taaaaagtac attaccacct gttcggctgg agaatctagt cgattagctc cctcttagtt
    60781 acaagcttaa agcgattttt taactaatac taaaccagat taaagaagga actagaacat
    60841 ctgtcttgta ctaatcaata tgctatttta aagtttcaaa taaacttgga atgctaatta
    60901 ttatatttac aataaatagt tgacttcgat agaaacagaa aatagaattc aacattcttc
    60961 cctacttata ccataataaa taagatccgc aagatagcct tttctctcta caccattaac
    61021 aatggtttgt agataggaca ttccagcctt ttccatgaca cgacctgaag ctgggttgag
    61081 actggcataa cgtgctctga ccttttgaaa acctgcttga gtaaaacaaa agtccaagat
    61141 agctttcaaa gtctctgtca tcataccatt tccccagtaa gccttgccta acacatagcc
    61201 aatttcacag cttaaatcag cctcgtctat cttaacaatg ctgatatctc ctatcacttg
    61261 ctctgggttt tcttttagac aaatggccca tttataatag ttgagattag tataggaagc
    61321 aacccaattg caaatcgagt ttcgagtgat ttcgacatca ggatggggat cccaggtaac
    61381 ataggtcaga ttctcagcgg atgaagccca attttgaaac atggcttctg catcactctc
    61441 cacaaatctt cttaaaatca aacgttctgt ctgtaatatt tgcgtaccga tagatttcat
    61501 gatgctacct cacttcctta tttctatgct cgtagtaaaa aggctcaact cagtaacagc
    61561 tagaaaacga gtttgtcttc taatttcttg acgcagtcgc tgcctggttt gaaatgcgct
    61621 ctagcaatct ttttcaaacc tagtcatcgt tgcaggggta agacgatgaa atcgaactct
    61681 tcgagttacc gaatctgcct cattttctta tttcaagatg agaggctgaa aacctccagt
    61741 ggaggttttt cttgcttttt aatttcaggg caagaagcta aaaaggtccc ccggaccttc
    61801 ttcgctttct catttctagg ctcagggtaa aaacctccaa tggaggtttt tactcccaaa
    61861 agtcatcaaa tacggtgatg ggtaagtggc gtttgtgttg gcctttgtgc caccagtttt
    61921 caatggtcgc ttgagcttct gggctgattg ttttgccttc taggtaatcg tcaatctctg
    61981 cataggtgac tccaagtgcg acttcgtcag ctaggcctgg tttgtcttct tctaggtctg
    62041 ccgttgggat tttttcataa agggctgggt ctgcaccaag ttcctgtaag agttgttttc
    62101 cttgacgttt attgaggcgg taaagaggga gaatatccgc accaccgtca ccaaacttgg
    62161 taaaaaagcc tgtgatattt tccgcggcgt ggtctgttcc aatgaccgct ccgctatggg
    62221 aaccagcaag ggcatactga gcaatcatac ggcaacgtgc cttgatattc cccttgttga
    62281 agtctgaaac aggactacct gtcgcttcaa ctgcagctgt catggtatca gctgattcct
    62341 tgatattcac aaccaagctg acatctggct ggatgaaggc tagggctttt tgagcatctg
    62401 cttcatcagc ttgcactccg tatggcaggc ggacagcgat aaatttgtag ctgtcgtctc
    62461 ccgtttcagc tcgcagttct tccatagcta attgcgccaa acgccctgcc aaggttgagt
    62521 cttgtccccc agaaatccct agtacaaagg tttttaggaa gggatgtttt ttcagatatc
    62581 tttttaagaa atcaatagaa cgacggattt cttcctgggc atcaatcact ggtttgacac
    62641 ccagctcttg gataatcgtt tcttgcaaac tcattcttct tctccttcac caagggcttc
    62701 cttgcgcatc ttatcaatca agtccatctt atcttgccat acatcacgcg ccaaatccac
    62761 tggatagtgc tgcggattga gcacacgctt atactcatcc cacaacttgt caaattcctt
    62821 acgggcataa tcctgaatgt cagtcaaact aggcaagttg taaactaata ttccttcttt
    62881 gaagatatcc accaagagag gaacggcatc aaaattacga accgtcttct tgatgtatgt
    62941 ataggtcgga tggaacatct tgatttctgt catgtcgcta atatccacac catcataagt
    63001 gatgtagtca ccttctgact tgcctttttc acgactggta atgcgccaca cctgcttctt
    63061 acctggcgtc gacacttttt ccgcattatt agacagctta atcgtattgc gcatctgacc
    63121 agtttcatct tcaattgcaa caatcttgta aaccgcccca agagccggct ggtcataggc
    63181 tgtaatcagc ttggtaccca caccccagac atcaatcttg gccttttgca tcttgaggtt
    63241 aaggatggta ttttcatcta gatcattaga agcataaatc ttagcctctg taaatccagc
    63301 ctcgtccagt tgctgacgga ctttcttaga aatgtaggca atatccccag agtcaatccg
    63361 cacacccata aagttaatct gatcacccag ctcacgcgcc acctgaatgg cagctggtac
    63421 accgatgcga agggtgtcat aggtatccac aagaaagaca caatttttgt gggtcgcagc
    63481 gtaagccttg aaagcttcat agtcattgcc ataaacctgt accaaggcat gggcatgggt
    63541 tcccaaaaca ggaatgtcaa agagcttacc cgcacgcacg ttgctggttc cattggcccc
    63601 accaatcacc gctgcgcgtg ttccccagat ggccgcatcc atttcttgag cccgacgtgt
    63661 cccaaactcc atcaagggtt catcttcgat aaccgaacga atacgagctg ccttcgtcgc
    63721 caccaaggtc tggtagttga cgatgttcaa aagagccgtt tcgaccaact gacattgggc
    63781 tagaggtcct tccacctgca caatcggttc attagcaaaa accaaatccc cttcttgggc
    63841 agaacgaacg gtcaactcca acttgaaatt gcgaaggtaa tccaagaacg ccccatgata
    63901 accaagcgac tccaaatagg ctatatcact atctgaaaaa cgtaagtctt caagatagtt
    63961 cacaattctt tccaaacctg caaaaaccgc atagccgttc ttaaaaggct gttggcggaa
    64021 atacacctca aagaccgcct tcttattgtg aatcccttgg tcaaagtaaa cctgcatcat
    64081 gttgatctgg tacaagtccg tgtgcaatgt caaactatca tctggataca tacttttcct
    64141 acttccttag ctagaaaccc atgaaaattt tcaagaactt tcatgtattc caataaatta
    64201 gtactattat atcacatttt agctggattg agaaaagagt aacaagctat tctccactct
    64261 ccaattcatc catatcttgt tcaaattttt tctgagccca ttcgccatag ctcttaagac
    64321 caagattgcc aataaagacc cacggaaggt aaatgacata tgtaatgacc ccagcagaca
    64381 ggtatttaaa attcaaagga ttgtgctgat aaatttctat gttgaattga taattctgca
    64441 acatcaaaag agccgtaata gccaaggtta ggaaaaaaca acccaaaatc gtaaaatgaa
    64501 aacgactata gtaggtcact cccagataac gggcgcgatt gaaaaagtaa aatgtcccta
    64561 tgatgataac gattagcagc atattagaat taaaaaggct tggtgctaat actgaaatga
    64621 tataagatag gagcgacaaa gcaatgcaga tatagaaact ttcagagccc gctttattga
    64681 acagttgttc ttctctttcg tctagtaatt gataataata aaatctattt ttcatcttct
    64741 tcctcccaaa atagttggtc tagggttttc cctaaacatc tgcaaataga ctggcagagc
    64801 gagagactgg gattgtattt tcccgcctct atcaaaccaa tagtctggcg tgtcaccccg
    64861 acagcctctg ccagttgacc ttgtgttaaa tcacgctcta cccgagctaa ttttaatttt
    64921 aaatttttag ccaccttcgt cctccttata gttttaatac tcatctactc ttaaaaaatc
    64981 caaaaccaac acaagctatc agctatttat tataacccca ttaatttgca ctccagtatt
    65041 atcttcagcc gaaaatcagt attttaggtt gtttgaaata aacttcctag tttactcttt
    65101 tatttttatt tagtattagc tttagtagaa tcttttaaac gagtttttat tgcttatatt
    65161 tcttgtttag tttagttggt ttcatatcac tattatataa tgcttttgga aatgagccta
    65221 gtataagtca aaaacgtgtt gaatagtgaa agcaggagca taccaagatg actgattttt
    65281 ttattgtatt ttaggtatgc aaaataatac taaatgaaac taaaatgaat acttcttgct
    65341 tttcttgaga gtgaaaaagt acaataaaat gattgtagtg attaccacaa gatactgact
    65401 aatagacatc gtatttgaag ccacaaatac aggtaaagaa taaaaaggaa gaagttcaat
    65461 tgctttgata aacaaatcat tactagtatt catcatcatc gtatttaata tattagggat
    65521 aaagagtagt aaagctacta aaataccaaa tcccaagcca cttttcaatt tgtataaata
    65581 gaaaatgtag gataatagaa aataaaacag gactaacaaa attgtattga ctacaatagc
    65641 tactataaaa tctaatccta aatcacctgg aatacccaat ttacttacga tgactagtaa
    65701 cacaatgcca ttcaaagcat aaataatgga aactgagatg gcatatagaa aattagacaa
    65761 gacgtaaatc atccgattct tctgttgatt ataaaacaaa cttaccgtat tgtgggaaaa
    65821 atctctacta atgactcgat tagcatgtat aacagccatt aacataccga gcatagcata
    65881 aaagtttgaa atatgcttaa taccaagcga tgtcccttga gtctttagaa taaagaatgt
    65941 aagcaatatc ggcggtataa acgagataag caaactgaga tatattacgc ctgatgaata
    66001 taaatttctt atattttcct taagaaaatt caatttattt aatttcatga ttataacctt
    66061 cctttatttt gaacgattta agtaaatatc tttaagcgtc tcttttttag tttcaaaatc
    66121 aactacttta atagagtttt cgttaaaaaa tttaaaaaac tcactacttt gaatattccc
    66181 agacatagta attctcagtc cctcttcctg aacaatatcc ccaaattctt gtttggtaat
    66241 gaaaatgtct ctatctgtag ctgatgaaaa agctatctca aacaagaaat tatgactatc
    66301 ttttcctact ttttgaaatg tcaaaagccc gttctccaag aaaagaactc tctcacaaat
    66361 ttcttcaatg tcttctaatt tatgactcga tattaaaatt cccacatttt catgtaaagc
    66421 taaatttttt agaaccgcta aaactatttg tgatgattca atatctaaac cattagtcgg
    66481 ttcatctaaa atcaatatat caggttccgt aacgagagtt agaagcaaag ctaatttttg
    66541 ttttgtaccc aaagaatagg tctttacttt tttattaata gactgagtca aatctaactc
    66601 ttggatcaaa cttctaaata tttcttgatt gtagtcaaca ccatataaat ttgacaaata
    66661 ttttaaattc tctaaacctg ttttagataa aaataatttt ggttcttcga ttaaataccc
    66721 aacattatca ctgcttataa tattacctga agtcggttga ttattctgaa caagaatttt
    66781 catcaacgta ctcttaccaa ctccatttct ccctgctaga ccaacaattt cacccttgtt
    66841 aagtgcaaaa tttatatctt tgagaatgat tgaataacca taatgcttac ttacatttat
    66901 aacttacatt ttttattcct ccattaatat tcatggtttg ctctttgatt cttattgagt
    66961 ttaaaaagtt gcacctcttt ttaacaatat tatatcatat atctaactta atgcaatata
    67021 taaatgtcat tttgtaaaat tttattaaca aaaaactctc tacaacaaaa taatagagag
    67081 ttttctgctt attaattttt ttcaaaatat ctaagacatc gcttctttgt ttaatttgat
    67141 aggctttaat acctaagctc cgactttatc acttaaaaaa taaaaaagga cagctaatct
    67201 cttgcgcatc aagggatttc gccattcttt aatctcgttt aagtgttgta tatggagctt
    67261 tgcataattt tttaaaacta aacaactaca ttaagcacga actgtgacgc tggttccatc
    67321 ttccttataa agattgataa gcccctcttt aagagctcga accatgtctc cagcttgaac
    67381 aggttgtggg actttaatag tcaatagttc cattggattt ggagcgcggt cgattttatt
    67441 gcctttggca tcatgcaaat cttcaatatc ggtttcaaaa tgacggaaac ctggaccata
    67501 aaactcaact tggtcccctt cgttaatgac gtttcgttga cgaatagttg ctgtttgtgc
    67561 cgcatcatca taagaaacca cttcagcgac aaacttgtac tcagggattt tacgacgagc
    67621 accaaacaac tgctcatttt cagatggtgt accatagtaa aatcctgtag ccagttcacg
    67681 ttgggcaacc ttccacatct cgtccaccaa gtcttgtttg atagcttcaa acttttcagg
    67741 actttcaaga taggcatcca cagccgcctt gtagcagttg gttactgttg atacatagtg
    67801 aatagactcc atacgtcctt cgatttttag actgtccaca ccattttcaa tcatatctga
    67861 gatatggtca atcatagaca tatcaacggc tgacattgaa aattcttctg gaatctcacc
    67921 ctgcaaactc ttacgttctt tcccaaatgg catatcgtaa aggtcgtact tccaacggca
    67981 tgactgagaa catccaccac ggttggcatc acgcatactc tagacggatt gttttgacaa
    68041 ttctaacctt ttagactttg cataataact gttaaacagt cgaaaattac cccagtttta
    68101 acaagtagtc aaaataccag ataaagtaaa aaggggctag gaaaaaagtc tttaaaatct
    68161 taaaaacgca tagtatcagg tattgaacaa tcttgatatt atgcgtttta ttgtgggaag
    68221 atttacttca ttttctcttg gaattgagtt ttctcctact tcaaaactag atgatttgct
    68281 atttaaaata gcgttcctta tgattttggc aacctggatt aaagcgagaa aaacaaaaga
    68341 ggcaacttaa gctttcttta tattgcttat atgttaatag ttttagacaa acaccacata
    68401 aaataggctt atcctgtatc aaagataagg gataaggctc aaaagggtga ttttctaatg
    68461 aatcatgaca ccgataacaa gcataatact ttttacaatc atagcattgt aaagcaataa
    68521 tatccagctt gctatggtaa tgaatgcatc ttgtttgctt atccactaag aaaccctgtg
    68581 cctctatcat ttccttttcc tttcttaagc tcgaactgtg acgctggttc catcttcctt
    68641 ataaagattg atgagtcctt cttttaatgc acgaaccatg tctcctgatt gaacgggttg
    68701 tgggacttta atagtcaata gttccattgg atttggagcg cggtcgattt tattgccttt
    68761 ggcatcatgc aaatcttcaa tataggtttc aaaatgacgg aaacctggac cataaaactc
    68821 aacttggtcc ccttcgttaa tgacgtttcg ttgacgaatg gttgctgttt gtgccgcatc
    68881 atcataagaa accacttcag cgacaaactt gtactcagga attttacggc gagcaccaaa
    68941 caactgctca ttttcagatg gtgtaccata gtaaaatcct gtagccagtt cacgttgggc
    69001 aaccttccac atctcgtcca ccaagtcttg tttgatagct tcaaactttt caggactttc
    69061 aagataggca tccacagccg ccttgtagca gttggttact gttgatacgt agtgaataga
    69121 cttcatacgt ccttcgattt ttagactgtc cacaccattt tcaatcatat ctggaatgtg
    69181 gtcaatcata gacatgtcaa cggctgacat tgaaaattct tctggaatct caccctgcaa
    69241 actcttacgt tctttcccaa atggcatatc gtaaaggtcg tatttccaac ggcatgactg
    69301 agaacatcca ccacggttgg catcacgcat actcatgtgg tttgaaagag tacaacgtcc
    69361 agagtatgaa atacacatag ctccatggac aaaggcttca atttcaacat ctgtacgttt
    69421 gcggatttca gctaattctt ccattgaaac ctcacgcgct aaaacgacac gagtcaagcc
    69481 tagctctttc cagaactcaa gggtttcata gttagtggca ctggcttggg tagaaaggtg
    69541 gatttcaaga cctggtgctt cagtcgctgc aatcataatc aaggctgggt cagatacgat
    69601 aactgctgca atcccgatat cacgcagttt acggaaccac tcaccagcac cagcttcatt
    69661 tccttcgtgc ataaccatat tagccgctac atagaccttg gcaccatact tggccgcaaa
    69721 ctgcacgcct tcttccatct gttcgaaagt aaagtttccc gcacggctac gaagaccata
    69781 ggcctgacca ccgataaaga cagcatctgc tccatactga acagctacct ttagcttctc
    69841 taaagttcct gcaggtgata aaacctcagg acgttttaat gtttttgtca tgatttctcc
    69901 tatttgcaat ataaaagttt gacatttttc cttctcattt tatagtaaat aaaggataaa
    69961 atcaagccta gacggattgt tttgacaatt ctaatctttt agactttgca taataactgt
    70021 taaacagtcg aaaattatcc cagttttaac aagtagtcaa aaagtctaga aaagtaaaaa
    70081 ccagtatcca aagatactga ctcgtaaaaa tacataaatt agtccttaga tgactactcc
    70141 cactctgttg ctcctataat ggaaaaggat tgatacagtc tagaatatcg cttttttatt
    70201 tattattctg atataaaact gttagaattg attttttgtt ttatacccaa atatgaatag
    70261 agacgtagct aataagttga ataacatatt tggaaaaatg agaaatagca atattactag
    70321 aacttttaga aacaatcaat atttaaaaag aaaaaagctc aaagaattta ttaaaccatg
    70381 ttataataga tatagctata attttattta taacaagagg atagaaatga ccgaattaga
    70441 aagaaaaaat cgaaaaatta gctaagaaat attctgataa cttaaacatc aaagttcaag
    70501 agagagttcg tgaaatggca aatgataata agagccatta tttgatatac agagttttag
    70561 gtatttcatt tgaagaagga gaaaatatcg atttgtatca aaataaaggt cgttttttat
    70621 acaaatatgc tggttcattt ttagaagaag ctgcagtact atgctttaac gaaaaatttg
    70681 gtacagaaaa tacttaaaaa gttaacattc ctaattctga aagtacaaaa cctaagactt
    70741 ttgaaattga ttgtttagtc ggagaaaaac acgcatacga aataaaatgg tgggatgcaa
    70801 ctacagatgg agaccatata actaaagaac acactagaat aaaagttatt cataacaaag
    70861 gatatatacc aattcggtta atgttctact atccaaatag aactcaagct ataaaaattc
    70921 agcaaacttt agaaacattg tataacggta ttggagggaa atattattat ggagattctg
    70981 cctgggaaca tttaagagca gtgaccggta ttgatttact tagtattcta acagatattg
    71041 caaataaaaa aacaggggta aaatcaaaat gacagtatta aaaggagata acttagaaat
    71101 attaaaaact attgaatcct caagtattga tttaatctat atggaccctc ctttctttac
    71161 acagaaaacc caaaaattat ctaataacaa aaatattatg tattcattcg aagatacgtg
    71221 gacttcgatt gaggattaca aagaattttt gtctgtaaga ttagaagaat gcaaaagagt
    71281 gctaaaaaat agtggcagta ttttcgttca ttgtgataaa attgcaaatc atcatattag
    71341 attaatttta gataatatct ttggagcaga tatgtttcaa agcgaaatta tatggaacta
    71401 taaacggtgg tctaattcaa aaaagggatt attgaacaat catcaaaaca tttactttta
    71461 ttcaaagtca aaagatttta aatttaatac aatttttaca gagtattctt ctactacaaa
    71521 tatcgaccaa atactagtag aacgaaaacg aaatggaaac tctaaaacta tatataaagt
    71581 tgataataat ggtaactata ttctagcaaa agagaaaaat ggagttcccc tttcagatgt
    71641 ttggaatata ccatttctta atccaaaagc taaagaaaga gtaggttatc ctacacaaaa
    71701 acctattctg ttattagaac aaattataaa gattgctact gataaaaatg atatagtttt
    71761 agacccgttc tgtggaagtg gaactacttt agtagcctcc aagattttga atagaaatta
    71821 tatggggatt gatttatctg aggaagctat caatataact cagcaacgtc tggaaaatgt
    71881 tataaaaaca agttcaaatt tattgaataa aggaatcgaa gcatatagaa ccaaaactga
    71941 ggaagaggaa aacattctta aattattaca ggcaaaaatt gttcaaagaa ataaaggaat
    72001 tgatggtttt ttacctaaac attttcaaaa aaaaccgata cctataaaaa ttcaaaaaaa
    72061 taatgaatgt ctgaatgaga gtatctcttt attacagaat gctataaact ccaaaaaact
    72121 tgattttgga gtagttataa aaactcattc agataattta ttatttgatt ttgatacgat
    72181 ccctgaaaat ataatagtag ttgaccattt tgaacttaca atcgaaaaat ggttaagtaa
    72241 aagtcaacag ttactatagt ttgcaaatta tttacagaaa gaacaaaaat gctctgaaac
    72301 actgatttca aagcattttt tgttagttta aaattactcc cattcttctt ttccaaacgt
    72361 acaatatatc caaaaccatt caaaatacta gattctattt tttataatat cactaaatcc
    72421 acctaattat aggacgtttt cagattttta gtcccgtccc agtcccagta ccggagaaat
    72481 attgttttaa tataatatct ctttttgtct tctaagctct taaaagcaaa agaacaagta
    72541 aagagtcaag acaaggataa aaagtccata ttagggcaaa taaaaagctt taagacagat
    72601 gacaaatcta agtcaaataa gaaagaccat agtaaaggtg cagagagata aatattggcg
    72661 gtcttcggac tgcctttatt tttttatcca tttttcaaat caaatttatt cagactatat
    72721 atgcacatat acacttaaat tcatataaaa acatggcttg taaaaaatta ctttaatcac
    72781 aataatcgca tttaaaattg tgatgtttgc aagctaaatt acggacttca cttggaagtt
    72841 ttcccttgta tcttttataa tagatagaaa atttgctggc agatgaatat ccaacagatt
    72901 ctgctatctc ttttatagat agttcagtgt ttaaaagaag agtttcagct acattcattc
    72961 tttttctttg agtgtactct gtaatgcttt gacaatattt ttccttaaat aaatttttta
    73021 atttagtacc actcatttta gatatttttt caagcgtgcc ttgatttaca ttcgttgcaa
    73081 aatgatcatc taagaatctt gctacatctt caagtgcttt atcatcatca atttcaattt
    73141 tatatttttt tctatttaag tatgtgtcaa ttactatact tatccattca tttgcctttg
    73201 ctttaaagaa aaaatcagcg gcaggagcgt ccatcttaca atttaatatt tccattgcca
    73261 ctctttctaa ggcctttgta agtataattt gattagtttg aagtaaagcc ccataaaatg
    73321 attctggatt aatgttaata gatgatagat gtttttccaa aagttctctt ttaaatccaa
    73381 tagaaacaca aagataatat gaattctcgt gtaataaaaa taggaagtca tctcttatat
    73441 tgtcaaagtc aaaagtacat aatgagtttg cagtaagtgt ttgataagga ctaaactttt
    73501 ctccatttgc gctgactatg tagcttgtgt atattgaaac ataatctgcc atactatagg
    73561 tactgttttg aactacttct tctctgatat aaaaatcatg tatatcgata atgaagctgc
    73621 ctccttcata aaaccaatat aggccttctg cataagttga attctctttt ttccaacaaa
    73681 atgtatgacc tgcacttgaa tacttctcat tgtttttaca ttcatctact ttcatataat
    73741 cttttacaaa atcataatat gacataacac actatccctt ttagacaata ttccaattag
    73801 ccttattaat tcaaaactat tgtattagta attataacag atgtataata gaaaagcaat
    73861 gatagatatt atcaattaag cgaatttata tctaaaaggg atattaaaga aaggagatat
    73921 gcttatgaag atttacaaaa aactatttgc ttatgtccaa gataagaaat atcttggggt
    73981 tttggccata attttttctg ctatatctgc tgcacttaca gtatatggat attatttaat
    74041 ctacaaattt ctagataagt taataattaa ttcaaactta tccggtgcag agagtatagc
    74101 attaaaatct gttattacac taacaagtgg agcgatattt tattttgtct caggaatgtt
    74161 ttcacatatc ttgggattta ggcttgaaac aaatttaaga aaaaggggaa tcgatggtct
    74221 ggaaaaagca agttttaggt tctttgactt aaatccatct ggtcaaataa gaaagatcat
    74281 agatgataat gcagcacaaa ctcatcaggt ggtagctcac atgattccag atagctctca
    74341 ggcaatagtc acacctatac ttgtccttgt actaggcttt atagtaagta taagggttgg
    74401 tataactttg cttgctctta ctataattgg cggcttaatt ttaggggcga tgatgggcga
    74461 gcaagaattt atgaagatat accaagaagc tctatctaaa ctaagtgctg agactgtcga
    74521 gtacgttaga ggaatgcagg ttgtaaaaat atttaaagca aatgtagagt cttttaaaag
    74581 cttttataag gcgataaaag attactcaaa gtatgcttat gattattccc tatcttgtaa
    74641 aaggccttat gttttgtatc aatggttatt ttttggactg attgcaattt taattattcc
    74701 tatagtttat tttatgacta gcttagctag cgcaaaggtg attttacttg agcttatcat
    74761 gattttattt ttatcaggag ttctctttgt ttcattcatg agaatgatgt ggtactccat
    74821 gtatatttct caaggaaatt atgcagtaga tactttagag gcgctttacg aagatatgca
    74881 aaaagacaaa ttagtgcatg gtaatgtcaa taattttaaa aactataata tagaatttga
    74941 gaatgttagc tttgcttata atgataaagc tgtcattgaa aatttatcct ttaatttaga
    75001 agaaggaaag tcctacgcac ttgtcggttc atctggatca ggcaaatcaa cagtagcaaa
    75061 acttatatca ggtttttaca atgttaataa aggaagcata aagataggcg ggatagcaat
    75121 aagtgaatat tctgacgaag ccttaattaa agccatttcc tttgtttttc aagattcaaa
    75181 attattcaag aagagcattt atgataatgt agctttagct aataaagatg cgacgaaaga
    75241 tgacgttatg agagccttaa aattagcagg atgcgattta atattagaca aattcccaga
    75301 aagagaaaat acaatcatag ggtcaaaagg tgtttattta tccggtggag aaaaacaaag
    75361 aattgcaatt gctagagcaa ttttaaagga ttccaaaatt attattatgg atgaagcatc
    75421 agcatctatt gacccagata acgagtttga gttgcaaaaa gctttcaaaa atcttatgaa
    75481 ggataaaaca gttatcatga ttgcacacag gctatctaca attaaagacc ttgatgaaat
    75541 tattgttatg gatagtggaa aaattataga aagagggtct gacaaagaat taatgtcaaa
    75601 agatacaagg tataagagcc tgcaagagat gtttaacagt gcgaatgaat ggagggtttc
    75661 aaatgaaaga gttttataaa aaaagatttg ctcttacaga tagaggagca agaaatttaa
    75721 gtaaagcaac actggcttca tttttcgttt attgtataaa catgcctcct gccatattac
    75781 ttatgatttt tgctcaggaa gttttggaaa atatgggcaa aagcaatggc ttttatatag
    75841 tattctcagt tttgactttg atagcaatgt atattttgct ttctatcgaa tacgataaat
    75901 tatataacac aacctatcaa gaaagtgcag atttaagaat aaggacagcg gagaatttat
    75961 caaaattacc tctatcttac ttttctaaac atgacatttc cgacatttca caaacaatca
    76021 tggctgatat tgaaggcata gagcatgcaa tgagccactc aataccaaag gtgggcggca
    76081 tggtactgtt tttcccatta atatctgtaa tgatgctagc gggcaatgtc aagatgggtt
    76141 tagctgtaat tattccatct attttaagct ttatatttat acctttatct aaaaaatatc
    76201 aggttaaggg acagaataga tattatgatg tcttaagaaa aaactcagaa agctttcaag
    76261 aaaatatcga aatgcaaatg gagattaaag catataattt atcgaaggat attaaagatg
    76321 acttatataa aaaaatggaa gatagtgaga gagtacactt aaaggcggaa gtaactacaa
    76381 ttttaacttt gtctatatct tcaatattta gctttatatc tcttgctgtt gtgatatttg
    76441 tcggcgtaaa tctaattatt aataaagaga taaattctct ctaccttata ggatatttac
    76501 tagctgctat gaagataaaa gactctttag atgcatctaa agagggcttg atggaaatat
    76561 tttatttatc gcccaaaata gaaagattaa aagaaattca aaatcaagat ttacaagaag
    76621 gcgatgacta tagtttaaaa aaatttgata ttgatctaaa agatgttgag tttgcctaca
    76681 ataaagacgc aaaagtttta aatggtgtaa gttttaaagc taagcaggga gaggtcactg
    76741 ctttggtagg tgcaagtggc tgcggtaaaa caactatctt gaaacttata tcaagacttt
    76801 atgattatga caagggacaa atcttaatcg atggcaaaga tataaaagaa atatcaacag
    76861 aatctctttt taataaggtc tctatagttt tccaagatgt ggttctcttt aatcaaagca
    76921 ttatggaaaa tattagaatc ggaaagcaag atgcaagtga cgaagaggtt aaaagagcag
    76981 caaaacttgc aaattgcaca gattttatag aaaaaatgga taaaggtttc gatacagtta
    77041 ttggtgagaa cggagctgag ctatcaggag gagaaagaca aagattatca atagccagag
    77101 ccttcttaaa agatgcgccg atattgatct tagatgagat aacagcaagc cttgatgtta
    77161 acaacgagaa aaagattcaa gagtctttaa ataatttagt taaagataaa actgttgtaa
    77221 tcatttcaca tagaatgaaa tccatagaaa atgcagacaa gatagtagtt cttcaaaacg
    77281 gaagagtaga aagcgaaggt aagcatgaag agcttttaca aaaatcaaaa atttacaaaa
    77341 atttaataga aaagacaaaa atggcagaag aatttattta ttaggaggac tacaatggat
    77401 aataaaaaat taaaagtaaa agatttagta agcatcggtg tttttggcgt aatttatttt
    77461 gccttcatgt ttggagttgg tatgatgggc ttgattccaa tattgttctt aatatacccg
    77521 acagtattag ccatagttgc aggaactgtt gttatgttat ttatggctaa ggttcaaaag
    77581 ccatgggcac tatttatatt tggtatgata tcaccacttg tgatgtttgc agctggtcat
    77641 acctacgtag ttgtggtttt atcacttata gtaatgataa tagcagaatt aattagaaag
    77701 attggtaatt ataattcatt taaatacaat atgctttctt atgcaatctt cagcacatgg
    77761 atatgtagct ctttaatgca aatgctttta gcaaaagaaa aatatatgga gtggtctttg
    77821 atgacgatgg gaaaagatta tgttgatgta ttagaaaagt taataactta tcctcatatg
    77881 gctttagtag ccttaggtgc tttcttagga ggaattcttg gagcatatat aggcaaggct
    77941 ctattgaaaa aacactttga aaaagcaggc attgtataat gcctactttt tcttcaaatg
    78001 ctccctttaa tcccaatccg atctctaaga tattagtcat atttatcaca ggcttaactg
    78061 ttatgcatag cataaacatc cgttttgagc tggcaattgt ttgtcttatt ggtattttgc
    78121 tttatttgaa tggatacaaa aaaacacttt tcaaatggat tatattgtgt gggatacttt
    78181 actccttgcc taattttatg gtgctatctg aattaaaccc tatagttaag atgtttttga
    78241 gtatacctat tgttattaga atgtttattt taccatttat ggcagcaagc tttatgataa
    78301 agacctcgga tgtaggcgca ataatttcat cgatggataa gcttaagatt tcaaagaatg
    78361 tatccatacc tattgcggtt atgtttagat tcttcccatc ttttaaggag gagaagaaaa
    78421 acatcaaaat ggctatgaga gtaagaggga taaattttaa aaacccagtc aaatatcttg
    78481 aatatgtttc tgtgccacta ctcattatat catctaatat atcagatgac attgcaaaag
    78541 cggcagaaac aaaggcaata gaaaatccaa ttgccaagac cagatacatt cgcgtaaaga
    78601 tacagctaat tgattttgtt tatgttttag cggttgctgg acttattgtg ggaggcttaa
    78661 tatggttgaa ataaaaaatt taagtcttga ttatggtgaa gagcatatat tagatgatat
    78721 atcactatcc atagccgagg gagagtgcgt gctatttaca ggaaaaagtg gaaatggtaa
    78781 gtcatcttta ataaattcaa tcaatggact agctgtaagg tatgataacg caaagacaaa
    78841 gggcaaaata attattgatg gtaagaatat aaaaaatttg gaactttatc aaatctcaat
    78901 gcttgtttca actgtttttc aaaatcctaa gacatatttt tttaatgtca atacgacatt
    78961 agaattatta ttttatttgg aaaatatcgg tcttgcaaga gaagagatgg acaggcgttt
    79021 gaaggatatg cttgagatat tcccgataaa aaatcttttg aacagaaata tatttaatct
    79081 atccggcggt gaaaaacaaa ttctttgcat tgcagcttct tatatagcag gtacaaagat
    79141 tatagttatg gatgagcctt catcgaattt agatattaaa agcataagtg ttttggcaaa
    79201 gatgctaaag atattaaaag agaaaggcat aagcataatt gttgcagagc atagaattta
    79261 ttatttgatg gacatagttg accgtgtatt tttaatagat aaaggaaagc ttaaaaaaac
    79321 ttatactaga agtgaatttt taaagctaga taaaaatgaa ttaaatgctt taagtttaag
    79381 agataaagaa ttaagtaaat taaaagttcc ttatttaaaa gaaggtggag agtatcagat
    79441 aaaaaatctt agctacaaat ttactgatga tgagtgttta agcttaaaag atatttcgtt
    79501 caagcttggg aaaatttatg gcataatagg atccaacgga cgaggaaaat caacgctttt
    79561 aagatgttta ataggtcttg agaaaaaatc aaaagaagaa atttatttta agggagagaa
    79621 gctatctaaa aaagaaagac tcaaaaactc ttcacttgtt atgcaagatg taaatcatca
    79681 attattcaca gatgaagtat tcaacgagct tagattagga gtaaagaatt ttgatgaaga
    79741 aaaggcgaaa atcatcttaa aagatttagg cctggacgaa tttattgaaa ggcatccgat
    79801 gagtttatca ggagggcaaa agcaaaggct tgcaatagca tctgttatgt gcaagaattc
    79861 tccatttgtc ttttttgacg aaccttcaag tggtatggat tattccaata tgataaaaat
    79921 atctgaactg attaataagt ataaaaccat ggataaaata atttttattg tttcccatga
    79981 tatagaattt ttaaatgaag tggcagatga aatttttgaa ttgtaaaata gagtctgtta
    80041 aacatgtcta tagaactagt aaattgtcta aaaatttaaa agatactaac acatattgat
    80101 atttattaga aaattaactt caggattttt acagtattta taaactttat aatatgtatt
    80161 tatagtatta ataatttcca tatctttagg gaaattcttt atttacttac cataattaaa
    80221 gagatgagag ataaatatcg gcagtcttcg gactgccttt atttttttac ttaatttaat
    80281 gcagtaaatc atacgattga aaggaatctg cgttatatgc tataattagg tggttaatct
    80341 atacatttag aaaggtaaaa tatagaattg gagaatgata tgggattttc atataataaa
    80401 ttgtaaccgt ccaataacga agtctattga aaaatctcca gactagagaa ctcacggata
    80461 gttcctaatc tggagatttc ttatttgcac ttttcttgta caactttagt ccacgataaa
    80521 taggcctcta aaacctcttt gtttacgaga gtttcctcgt ttggaagaca ttctagaaga
    80581 taggatagat atttctcact atttagttga tgacgtttag ctgtttccaa taagctcata
    80641 ataatagctc ttgctttagc tccttcaaaa actttgagaa aa
//
LOCUS       DBEJZV010000006        75914 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.06, whole genome shotgun sequence.
ACCESSION   DBEJZV010000006 DBEJZV010000000
VERSION     DBEJZV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 75914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75914
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.06"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            5..75
                     /locus_tag="ACL3S0_000476"
     tRNA            5..75
                     /locus_tag="ACL3S0_000476"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            111..184
                     /locus_tag="ACL3S0_000477"
     tRNA            111..184
                     /locus_tag="ACL3S0_000477"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:145..147,aa:Ile,seq:gat)
     gene            191..278
                     /locus_tag="ACL3S0_000478"
     tRNA            191..278
                     /locus_tag="ACL3S0_000478"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:225..227,aa:Ser,seq:gct)
     gene            complement(404..1339)
                     /gene="birA"
                     /locus_tag="ACL3S0_000479"
     CDS             complement(404..1339)
                     /gene="birA"
                     /locus_tag="ACL3S0_000479"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGR1311449.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1336..2196)
                     /locus_tag="ACL3S0_000480"
     CDS             complement(1336..2196)
                     /locus_tag="ACL3S0_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR1311450.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2304..4466
                     /locus_tag="ACL3S0_000481"
     CDS             2304..4466
                     /locus_tag="ACL3S0_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGR1311451.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENQNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHTQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4558..5817
                     /locus_tag="ACL3S0_000482"
     CDS             4558..5817
                     /locus_tag="ACL3S0_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR1311452.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5831..6697
                     /locus_tag="ACL3S0_000483"
     CDS             5831..6697
                     /locus_tag="ACL3S0_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1311453.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6711..7544
                     /locus_tag="ACL3S0_000484"
     CDS             6711..7544
                     /locus_tag="ACL3S0_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1311454.1"
                     /translation="MKQDERKALIGKYILLILGTVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7551..7691
                     /locus_tag="ACL3S0_000485"
     CDS             7551..7691
                     /locus_tag="ACL3S0_000485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311455.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKATLTWFEEI
                     FE"
     gene            7902..9344
                     /gene="gtfA"
                     /locus_tag="ACL3S0_000486"
     CDS             7902..9344
                     /gene="gtfA"
                     /locus_tag="ACL3S0_000486"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGR1311456.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFRDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9482..10675
                     /locus_tag="ACL3S0_000487"
     CDS             9482..10675
                     /locus_tag="ACL3S0_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGR1311457.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11362..13341
                     /locus_tag="ACL3S0_000488"
     CDS             11362..13341
                     /locus_tag="ACL3S0_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1311458.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNVDKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13408..14904
                     /locus_tag="ACL3S0_000489"
     CDS             13408..14904
                     /locus_tag="ACL3S0_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311459.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14904..15830
                     /gene="oppC"
                     /locus_tag="ACL3S0_000490"
     CDS             14904..15830
                     /gene="oppC"
                     /locus_tag="ACL3S0_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGR1311460.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15839..16906
                     /locus_tag="ACL3S0_000491"
     CDS             15839..16906
                     /locus_tag="ACL3S0_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311461.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16917..17843
                     /locus_tag="ACL3S0_000492"
     CDS             16917..17843
                     /locus_tag="ACL3S0_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1311462.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            18334..19271
                     /locus_tag="ACL3S0_000493"
                     /pseudo
     CDS             18334..19271
                     /locus_tag="ACL3S0_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            19283..20160
                     /locus_tag="ACL3S0_000494"
                     /pseudo
     CDS             19283..20160
                     /locus_tag="ACL3S0_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            20173..20976
                     /locus_tag="ACL3S0_000495"
     CDS             20173..20976
                     /locus_tag="ACL3S0_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311463.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGRN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(21009..21719)
                     /gene="treR"
                     /locus_tag="ACL3S0_000496"
     CDS             complement(21009..21719)
                     /gene="treR"
                     /locus_tag="ACL3S0_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGR1311464.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21904..23871
                     /gene="treP"
                     /locus_tag="ACL3S0_000497"
     CDS             21904..23871
                     /gene="treP"
                     /locus_tag="ACL3S0_000497"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGR1311465.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QCVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24049..25674
                     /gene="treC"
                     /locus_tag="ACL3S0_000498"
     CDS             24049..25674
                     /gene="treC"
                     /locus_tag="ACL3S0_000498"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGR1311466.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25816..26064
                     /locus_tag="ACL3S0_000499"
     CDS             25816..26064
                     /locus_tag="ACL3S0_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGR1311467.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26271..27065
                     /gene="racE"
                     /locus_tag="ACL3S0_000500"
     CDS             26271..27065
                     /gene="racE"
                     /locus_tag="ACL3S0_000500"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGR1311468.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27062..28033
                     /locus_tag="ACL3S0_000501"
     CDS             27062..28033
                     /locus_tag="ACL3S0_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGR1311469.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28009..28530
                     /locus_tag="ACL3S0_000502"
     CDS             28009..28530
                     /locus_tag="ACL3S0_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR1311470.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28527..28988
                     /gene="cbpB"
                     /locus_tag="ACL3S0_000503"
     CDS             28527..28988
                     /gene="cbpB"
                     /locus_tag="ACL3S0_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGR1311471.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28985..29719
                     /gene="xerD"
                     /locus_tag="ACL3S0_000504"
     CDS             28985..29719
                     /gene="xerD"
                     /locus_tag="ACL3S0_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGR1311472.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29719..30447
                     /locus_tag="ACL3S0_000505"
     CDS             29719..30447
                     /locus_tag="ACL3S0_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGR1311473.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30466..31035
                     /gene="scpB"
                     /locus_tag="ACL3S0_000506"
     CDS             30466..31035
                     /gene="scpB"
                     /locus_tag="ACL3S0_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGR1311474.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31022..31744
                     /locus_tag="ACL3S0_000507"
     CDS             31022..31744
                     /locus_tag="ACL3S0_000507"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR1311475.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31744..31986
                     /gene="yidD"
                     /locus_tag="ACL3S0_000508"
     CDS             31744..31986
                     /gene="yidD"
                     /locus_tag="ACL3S0_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGR1311476.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(32211..33176)
                     /locus_tag="ACL3S0_000509"
     CDS             complement(32211..33176)
                     /locus_tag="ACL3S0_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1311477.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQKVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33272..34024)
                     /locus_tag="ACL3S0_000510"
     CDS             complement(33272..34024)
                     /locus_tag="ACL3S0_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311478.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(34021..34977)
                     /locus_tag="ACL3S0_000511"
     CDS             complement(34021..34977)
                     /locus_tag="ACL3S0_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGR1311479.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(34967..35926)
                     /locus_tag="ACL3S0_000512"
     CDS             complement(34967..35926)
                     /locus_tag="ACL3S0_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311480.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSILFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36223..36333)
                     /locus_tag="ACL3S0_000513"
     CDS             complement(36223..36333)
                     /locus_tag="ACL3S0_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGR1311481.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            complement(36349..37050)
                     /gene="galE"
                     /locus_tag="ACL3S0_000514"
     CDS             complement(36349..37050)
                     /gene="galE"
                     /locus_tag="ACL3S0_000514"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR1311482.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHYAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37450..38514
                     /gene="pepA"
                     /locus_tag="ACL3S0_000515"
     CDS             37450..38514
                     /gene="pepA"
                     /locus_tag="ACL3S0_000515"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGR1311483.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKDEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38536..38832
                     /locus_tag="ACL3S0_000516"
     CDS             38536..38832
                     /locus_tag="ACL3S0_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR1311484.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39514..39957
                     /locus_tag="ACL3S0_000517"
     CDS             39514..39957
                     /locus_tag="ACL3S0_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR1311485.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            39961..40725
                     /locus_tag="ACL3S0_000518"
     CDS             39961..40725
                     /locus_tag="ACL3S0_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGR1311486.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTETFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            40740..41468
                     /locus_tag="ACL3S0_000519"
     CDS             40740..41468
                     /locus_tag="ACL3S0_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1311487.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41461..42981
                     /locus_tag="ACL3S0_000520"
     CDS             41461..42981
                     /locus_tag="ACL3S0_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGR1311488.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            43326..44132
                     /gene="pnuC"
                     /locus_tag="ACL3S0_000521"
     CDS             43326..44132
                     /gene="pnuC"
                     /locus_tag="ACL3S0_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGR1311489.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(44298..44834)
                     /gene="sczA"
                     /locus_tag="ACL3S0_000522"
     CDS             complement(44298..44834)
                     /gene="sczA"
                     /locus_tag="ACL3S0_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGR1311490.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTGQEVVQFYLDLLIPKN"
     gene            44967..45857
                     /gene="czcD"
                     /locus_tag="ACL3S0_000523"
     CDS             44967..45857
                     /gene="czcD"
                     /locus_tag="ACL3S0_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGR1311491.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            46101..46454
                     /gene="nmlR"
                     /locus_tag="ACL3S0_000524"
     CDS             46101..46454
                     /gene="nmlR"
                     /locus_tag="ACL3S0_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGR1311492.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            46455..47492
                     /locus_tag="ACL3S0_000525"
     CDS             46455..47492
                     /locus_tag="ACL3S0_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGR1311493.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(47538..48545)
                     /gene="galR"
                     /locus_tag="ACL3S0_000526"
     CDS             complement(47538..48545)
                     /gene="galR"
                     /locus_tag="ACL3S0_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGR1311494.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            48709..49887
                     /locus_tag="ACL3S0_000527"
     CDS             48709..49887
                     /locus_tag="ACL3S0_000527"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGR1311495.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            49906..51387
                     /locus_tag="ACL3S0_000528"
     CDS             49906..51387
                     /locus_tag="ACL3S0_000528"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR1311496.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKAQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGISLD"
     gene            51457..51861
                     /locus_tag="ACL3S0_000529"
     CDS             51457..51861
                     /locus_tag="ACL3S0_000529"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGR1311497.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            52042..52806
                     /locus_tag="ACL3S0_000530"
     CDS             52042..52806
                     /locus_tag="ACL3S0_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HGR1311498.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            52803..53264
                     /locus_tag="ACL3S0_000531"
     CDS             52803..53264
                     /locus_tag="ACL3S0_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HGR1311499.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(53315..54577)
                     /locus_tag="ACL3S0_000532"
     CDS             complement(53315..54577)
                     /locus_tag="ACL3S0_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGR1311500.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIFVASLLAIVLNAVLNHKKK"
     gene            complement(54577..55158)
                     /locus_tag="ACL3S0_000533"
     CDS             complement(54577..55158)
                     /locus_tag="ACL3S0_000533"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGR1311501.1"
                     /translation="MKLLEERILKDGHILDDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVLFKEADL"
     regulatory      complement(55558..55653)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(56036..56275)
                     /locus_tag="ACL3S0_000534"
     CDS             complement(56036..56275)
                     /locus_tag="ACL3S0_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HGR1311502.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(56323..56418)
                     /locus_tag="ACL3S0_000535"
                     /pseudo
     CDS             complement(56323..56418)
                     /locus_tag="ACL3S0_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
     gene            complement(56430..57257)
                     /locus_tag="ACL3S0_000536"
     CDS             complement(56430..57257)
                     /locus_tag="ACL3S0_000536"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGR1311503.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            57391..57847
                     /locus_tag="ACL3S0_000537"
                     /pseudo
     CDS             57391..57847
                     /locus_tag="ACL3S0_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            57919..58296
                     /locus_tag="ACL3S0_000538"
     CDS             57919..58296
                     /locus_tag="ACL3S0_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGR1311504.1"
                     /translation="MKRLIDGKPTLLIKNGNIDPEACRSVGLSASDVSLKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYE"
     gene            58502..60247
                     /locus_tag="ACL3S0_000539"
     CDS             58502..60247
                     /locus_tag="ACL3S0_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HGR1311505.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALILVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            60237..61988
                     /locus_tag="ACL3S0_000540"
     CDS             60237..61988
                     /locus_tag="ACL3S0_000540"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311506.1"
                     /translation="MQNKQEQWAVLKRLMSYLKSYGLLIFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKVLILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            62161..62853
                     /locus_tag="ACL3S0_000541"
     CDS             62161..62853
                     /locus_tag="ACL3S0_000541"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR1311507.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNCRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            62896..64122
                     /locus_tag="ACL3S0_000542"
     CDS             62896..64122
                     /locus_tag="ACL3S0_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGR1311508.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            65252..67411
                     /gene="pfbA"
                     /locus_tag="ACL3S0_000543"
     CDS             65252..67411
                     /gene="pfbA"
                     /locus_tag="ACL3S0_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGR1311509.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYNIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            67395..67691
                     /locus_tag="ACL3S0_000544"
     CDS             67395..67691
                     /locus_tag="ACL3S0_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311510.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            67933..68241
                     /locus_tag="ACL3S0_000545"
                     /pseudo
     CDS             67933..68241
                     /locus_tag="ACL3S0_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            68405..69064
                     /locus_tag="ACL3S0_000546"
     CDS             68405..69064
                     /locus_tag="ACL3S0_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGR1311511.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            69089..70156
                     /locus_tag="ACL3S0_000547"
     CDS             69089..70156
                     /locus_tag="ACL3S0_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR1311512.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            70260..71270
                     /locus_tag="ACL3S0_000548"
     CDS             70260..71270
                     /locus_tag="ACL3S0_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311513.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFIIPSDVL
                     QF"
     gene            71282..72973
                     /locus_tag="ACL3S0_000549"
     CDS             71282..72973
                     /locus_tag="ACL3S0_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311514.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            72976..73686
                     /locus_tag="ACL3S0_000550"
     CDS             72976..73686
                     /locus_tag="ACL3S0_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGR1311515.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            73782..74150
                     /locus_tag="ACL3S0_000551"
     CDS             73782..74150
                     /locus_tag="ACL3S0_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311516.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYSSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            74258..75259
                     /locus_tag="ACL3S0_000552"
     CDS             74258..75259
                     /locus_tag="ACL3S0_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1311517.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    75471..75700
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT        22612 a        13553 c        16730 g        23019 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttcaa attaccaagt tttttaactt gggcgcgtag
      121 ctcaggtggt tagagcgcac gcctgataag cgtgaggtcg gtggttcgag tccactcgtg
      181 cccattaatt ggagaattac tcaagaggct gaagaggacg gtttgctaaa tcgttaggtc
      241 gggtaactgg cgcaagggtt cgaatccctt attctccgtt ttaatgagag tttgtaactc
      301 tcttttttat ttttagagcc aataaaactt cagatccgta aaacttaatt gaattactaa
      361 tctgaagtta tttttatatc gtttatatta taattgtgtt attttacttc caactattga
      421 gagaaatttc gccactattt agccagattt cttttccgtt atcacattga actaaaagtt
      481 ttccattttc tgagatgtct ttagcaagtc ccttgtagtc tttttgctct agtgtgaaag
      541 tgacttcttt tcctagaatg aatgactgtt ttttgtatag gtataatagc tcttctgctg
      601 gtgtttcgaa gaaagcacgc cagatttcta tgatcaattc attccttgtt ataggagctg
      661 tagctttaaa taagctggca gctttttctt ttaattcctg agggaagtct ttaatagtga
      721 aattgatacc tactccaata atgatatctg tgactaagcc agtttctaca gaggtcattg
      781 cttcagtaag gattcctcca attttatgat tgtttagata gatatcattg acccatttta
      841 tgtcgacatc tattaaagtt aggttcttaa tggctttgta gacagctcca gctacaagta
      901 gtgtgtagga tggtaatttg tcatagggga gatttggttt aagatggagt gtcatataaa
      961 taccaccttg tggtgagtag aaggaacgtt gaaaacggcc tcggcctgct gtttgatagg
     1021 aagctagata gagggtattt gcttcatggc ctaaatcaat tgcttctttt gcatctagtt
     1081 gtgttgattt tgtttcgggt ttaaagctga ctttaattgg aagattttct tctagaatct
     1141 ctggaagaat aaggtcacca ttcatcagtt tatatcctct atttttgata ctatcaattt
     1201 caatgccttc ttgttctagt cgcttgatgg ctttccaaat tgctgttcgg cttagggata
     1261 gtttttctgc gattttttct ccgctgatat agtcggtttc tttagatagg atttggtaga
     1321 cagcttggta ggatttcata atgttgcctt tcttactagt tggtattgag agtattcttt
     1381 tcttgtatga cttggagtct gattaaagta ttgtttataa gctttcgaaa aatggagtgg
     1441 atctgaaaaa cctaccgagt atgcaattac cttgatggac tcttgggtat tttcgagaag
     1501 ttgtctagct cggtgcattc gaacgtagag taggtattct ttgggtgata aggtattaaa
     1561 ttctttgaat acgcttgata agtagcttct gtgaacggat agttcttttg ctaaatcttg
     1621 aattgtaagt gattgaggat agtggctatc aattaatcgt ttgcattcaa gatagagttg
     1681 gtgggttgat gaaatattct tttttttctg attgggagca atagttccca gatgaaacat
     1741 cagttcatga agttgtccca tgatatggag ttgagctaat tcacttgatt ttgtaatctg
     1801 agcgaagcgg acaatgtctg agatgagttt tgcagtagtc tgggtatgac aagtttcaga
     1861 ttggatgaga taggattgat cagaaatttg agaaagagca aaataatcag gggatttccc
     1921 tccagtgatt cctaaccagt agtaggccca aggttcttta ctatctgctt gataaaaggt
     1981 tagttcctct ggttttaata gaaagaaatc tccttctttt aaatcaacaa ttttaccctt
     2041 gtaataaaat tttccttgtc ctttagtaat gtaatgtaga acgtatgtat cacgaatggc
     2101 tggaccaaaa gagtaattag gtgtgcattc ctcatatcca taaaagctta gggcaaggtc
     2161 gattgttcca gtctggtatt ctgaaaaaac taacatgtgc tacctcccac ctaacatttt
     2221 accatattct tgagacattt ttctattttg gaaagcgatt tcaggtgata aaatataatc
     2281 aataaagtga tgaggtgaag taaatgggag ttaggataga gaataatcta ttttatgttg
     2341 agagtaaaaa tctaagtttg attattgaaa atcaaaatgg ctacttactt ttgaaacatt
     2401 taggaaagac tattaagaac tataaaggtt ccaatagtgt ttatgaacga gaccatgcct
     2461 tttcaggaaa tccaacggct actaatcgaa cctttagttt agatactcag cgacagattt
     2521 ttggacaaca tggcttagga gattttagga aaccaaccat acaggttcag catagtgtaa
     2581 ctgaagtaac agactttcga tttgtagaag caaagatttt aaaaggtcag aatggtccac
     2641 agggcttacc ttctccacat agcatggacg atacagagac tcttgtctta atgttagaag
     2701 attctaaggc tcaacttagt ctgactttgt attatactac ttttaataat gatgcgacta
     2761 ttgctagcta cagtaaatta gataataata gtaatcagga agttgtcatc cataaagatt
     2821 tttcttttat ggctgatttt ccagctgcag attacgaaat agtaactctg cagggtgctt
     2881 atgctcgtga aaagactgtt agacgtcaac aggtagaaca aggaatcttt tcgattagct
     2941 caaaccgagg tgcttctggt catactcaaa caccagctct tctactatgc gaacaaggag
     3001 tcacagagga tgctgggaat gtgtttgcta ttcaactaat gtatagtggc aactttgaag
     3061 cttttgttca aaaaaatcaa ttgaatgaag ttcgggtggc tattggcatt aatccagaaa
     3121 acttttcttg gaagttagcc cctgaggaat actttgaaac accggtagct ttagtgactc
     3181 attcagatca gggattaact ggtattagtc atgaaagtca gaattttgta ctgaagcaca
     3241 ttatgctaag tgaattttct aaaaaagaac gtccaattct aatcaataac tgggaagcta
     3301 cttactttga ctttcagaga gaaaaactgt tagagttagc agatgaagct aagaaagttg
     3361 gcattgaact ttttgtatta gatgatggtt ggtttggcaa tcgttttgat gataatcgtg
     3421 ctttaggtga ttgggttgtt aatgaggaaa aactgggtgg aagtctagaa agtctgattt
     3481 cagctatcca tgaaagaggt ttgcagtttg gactttggtt agaacccgaa atgatttctg
     3541 tagatagtga tttgtatcgt cgacatcctg actgggctat tcaggttcct gactatgagc
     3601 atacttattc tcggaatcaa ttagtactta atcttgccaa tcctcaggta gtagaatact
     3661 tgaaaagtgt cttagatcaa ctcctatctt atcatgatat tgattacatt aaatgggata
     3721 tgaaccgcaa tatcactaag ctagggaatg gattaactta tctagagaca cagatgcaat
     3781 ctcatcagta catgctgggg ctttacgaac tcgtttctta tctgacagag aagcacagcc
     3841 atattctctt tgagtcctgc tctggtggtg gtggacgaaa tgatcttggt atgatgcgct
     3901 atttcccaca agtctgggct agtgataata ctgatgccat tgcacgttta ccaattcaat
     3961 acggttcatc ctatctctat ccaaccattt ctatgggggc tcatgtgtca gcagtaccaa
     4021 atcatcagat gggacgaatg acaccattag aaacacgtgg ccttgtagca atgatgggaa
     4081 atttgggcta tgaacttgat ttgacaaatt tatcagatga agagaaagct acgattgcta
     4141 atcaggtgaa cttgtataaa gaattacgac cagtagttca gttaggacag cagtatagac
     4201 taattaatcc tgatactgca tccaatgaag cagctgtaca atttaattac ggaaatcaaa
     4261 cgattgtaac ctacgttcgc gttttatctg ttgtagagac catggaaaca actttaaaat
     4321 taaaagattt ggatgaagag ggactatata aattacagga aaatggcgaa gtttactcag
     4381 gtgcagaact aatgtatgcg ggcttaactg ttatcttatc ccaaggagat tttttgagta
     4441 gacagtatat ttttagaaaa ctatgatatg tactgacctc aaaagttaga tttattctat
     4501 ctaacttttg aggtgcagtt tgataagggt gtataaattt ataaaggagg ctttctaatg
     4561 gaatggtata aaaaaatcgg acttcttgca actacaggtt tagctttgtt tgggctcggt
     4621 gcttgctcca actatggtaa atctgcggat gacacagtga ccatcgagta tttcaaccag
     4681 aaaaaagaaa tgaccaaaac cttggaagaa atcactcgtg attttgagaa ggaaaaccct
     4741 aagataaagg tcaaagtcgt caatgtacca aatgctggtg aagtattgaa gacacgcgtt
     4801 ctcgcaggag atgtgcctga tgtggtcaat atttacccac agtccatcga actgcaagaa
     4861 tgggcaaaag caggtgtctt tgaagatttg agtaacaaag actacctgaa acgcgtgaaa
     4921 aatggctacg ctgaaaaata tgctgtaaac gaaaaagttt acaacgttcc ttttacagct
     4981 aatgcttatg gaatttacta caacaaagat aaattcgaag aactgggctt gaaagttcct
     5041 gaaacctggg atgaatttga acagttagtc aaagatatcg ttgctaaagg acaaacacca
     5101 tttggaattg caggtgcaga tgcttggaca ctcaatggtt acaatcaatt agcctttgcg
     5161 acagcaacag gtggaggaaa agaagcaaat caataccttc gttattctca accaaatgcc
     5221 attaaattgt cggatccgat tatgaaagat gacatcaagg tcatggacat ccttcgcatc
     5281 aatggctcta agcaaaagaa ctgggaaggt gctggctata ccgatgttat cggagccttc
     5341 gcacgtgggg atgtcctcat gacaccaaat gggtcttggg cgatcacagc gattaatgaa
     5401 caaaaaccga actttaagat tgggaccttc atgattccag gaaaagaaaa aggacaaagc
     5461 ttaaccgttg gtgcgggaga cttggcatgg tctatctcag ccaccaccaa acatccaaaa
     5521 gaagccaatg cctttgtgga atatatgacc cgtccagaag tcatgcaaaa atactacgat
     5581 gtggacggat ctccaacagc gatcgaaggg gtcaaacaag caggagaaga ttcaccgctt
     5641 gctggtatga ccgaatatgc ctttacggat cgtcacttgg tctggttgca acaatactgg
     5701 accagtgaag cagacttcca taccttgacc atgaactatg tcttgaccgg tgataaacaa
     5761 ggcatggtca atgatttgaa tgccttcttt aacccgatga aagcggatgt ggattaggag
     5821 tagagagact atgaaaaaag tattacaaaa atattgggca tgggcttttg tggtcatccc
     5881 cctcttgtta caagcaattt tcttctatgt gccgatgttt caaggagcct tttacagttt
     5941 taccaactgg acaggattga cttataacta caaatttgtc ggcttaaaca actttaagct
     6001 cctcttcatg gatccaaaat tcatgaatgc gattggcttt accgcaatca ttacgattgc
     6061 catggtggtt ggtgagattg cactcgggat cttcattgcg cgtgtcttga attctaaaat
     6121 caaaggccaa accttcttcc gtgcttggtt cttcttccca gctgttttat ctggtttgac
     6181 agtggctttg atcttcaagc aagtcttcaa ctacggtctt ccagcgattg ggaatgccct
     6241 tcatattgaa tttctccaaa ccagtctttt agggactaag tggggagcaa tctttgcggc
     6301 tgtctttgtc cttctttggc aaggggtggc tatgcccatc atcatcttcc tagctggttt
     6361 gcaatctatt ccaactgaga ttacagaggc agcaaggatt gatggtgcga ctagcaagca
     6421 agttttctgg aacattgaat tgccttactt gctaccaagt gtctctatag tctttatcct
     6481 agccctaaaa ggtgggctga ctgcctttga ccaagtcttt gccatgaccg gtggtggtcc
     6541 aaacaatgcc acaacctcac ttgggctctt ggtttataac tatgccttta aaaacaacca
     6601 attcggttat gccaatgcca ttgccgtaat cttgttcttc ttaattgtag tgatttcgat
     6661 catccaattg agagtatcta agaaatttga aatttaagag gagaagcatg atgaaacaag
     6721 atgaaagaaa agccctgatt ggcaaataca ttctattgat tctaggaacg gttctgattt
     6781 tagtgccgct ccttgctacc ctctttagtt ccttcaaacc cactaaggat attgtagata
     6841 atttctttgg ttttccaacc aacttcacat gggacaactt tagccgtctc ttagctgatg
     6901 ggattggagg ctattattgg aactctgtcg tcatcactgt cttgtcttta cttgcagtaa
     6961 tgatctttat ccctatggca gcctactcca tcgctcgcaa tatgagtaaa agaaaagcct
     7021 ttaccatcat gtataccctc ttaatcctcg gaatcttcgt acctttccaa gtcatcatga
     7081 ttccgattac ggttatgatg agtaaactcg gtttggctaa tacctttggt ttgatcttgc
     7141 tctacttgac ctatgcgatt ccacagaccc tctttctcta tgttggctat atcaaaatct
     7201 cgattccaga aagtctggat gaagcagcag agatcgatgg ggctaatcaa tttacaacct
     7261 atttccgcat catcttccca atgatgaaac cgatgcatgc gacaaccatg atcatcaatg
     7321 ccctttggtt ctggaatgac ttcatgttgc cactccttgt cttgaaccgg gattccaaaa
     7381 tgtggactct gcctttgttc caatacaact acgcaggcca atatttcaac gactacggac
     7441 caagctttgc ctcttacgtg gtcggcatta tcagtatcac cattgtctat ctcttcttcc
     7501 aacgccatat catttcagga atgagcaacg gggcagtgaa gtaatactca atgaaaatca
     7561 aagagcaaac taggaagcta gccgcaggtt gctcaaaaca ctgttttgag gttgtggatg
     7621 aaactgacga agtcagtaac catacctacg gtaaggcaac gctgacgtgg tttgaagaga
     7681 ttttcgaata gtataagaag agctcatgga atctatagtc tttgacacag aggaagagtt
     7741 cagcttgttg ataattctat gtagaaaaca agaaagtagt actttgttta tcacagtcta
     7801 tattagtacg agtttgatga taaatagaga tttaaaatga attttattta tgaagccaga
     7861 tcatatgaga cttggcttca attagaaaaa ggagagtaat gatgccaatt caaaataaaa
     7921 ccatgttgat tacctattct gatagccttg gaaataatct taaagactta tatgataatt
     7981 tggaagagca ttttcgagat gctattggag gagttcacct tttaccattt ttcccatcaa
     8041 caggtgatcg tggatttgcg ccagttgact acgacgaagt ggactcagct tttggtgatt
     8101 gggaggatgt taagcgttta ggtgagagat attatcttat gtttgatttt atgattaatc
     8161 atatttctcg tcaatccaag tattataagg actatcaaga aaaacatgaa gccagtgaat
     8221 ttaaagctct ctttttaaac tgggataagt tttggccaga aaaccgtccg acacagtctg
     8281 atgtagattt aatttacaag cgtaaggatc gtgcaccaaa gcaagagatt gtgtttgaag
     8341 atggttcagt ggaacatttg tggaatacct ttggtgaaga gcagattgat cttgatgtga
     8401 ccaaagaagt aactatggaa tttatccgta agaccattca gcacttggca agtaatgggt
     8461 gtgatttgat tcgtctagat gcctttgctt atgcagtgaa gaaattggat actaatgatt
     8521 tctttgtgga accagatatt tgggatttat tggacaaagt tcgagatatc gctgctgagt
     8581 atgggacaga gcttttacct gagattcatg aacactattc gattcagttt aaaatagcag
     8641 accatgatta ctatgtttat gattttgctc ttccaatggt gacactttat actctttaca
     8701 gttccagaac agagcgtttg gctaagtggt taaagatgag cccgatgaag caatttacga
     8761 cgctagatac ccatgatggg attggagtag tagatgtcaa ggatatcctg accgatgagg
     8821 agattgacta tgcttcaaat gaactctata aggttggagc caatgtcaaa cgtaagtact
     8881 ctagtgccga gtataacaac ttagatatct accaaatcaa ttcaacctac tattcagcgc
     8941 ttggagatga tgatgtcaag tattttctcg ctcgtctaat tcaagctttt gccccaggta
     9001 ttcctcaggt ttactatgtg ggtctattag caggcaagaa tgacttgaaa ttattagaag
     9061 aaactaaaga aggtcgaaat attaatcgtc attactatag caacgaggaa atagcaaaag
     9121 aagtgcaacg acctgttgtg aaggcccttc tcaatctatt ttctttccgt aaccgttcag
     9181 aagcctttga tctagaaggg actactgaga tagagacacc aacagctcac agcattgtaa
     9241 tcaaacgtca aaataaagat aagtccgtaa cagcagtagt agaaattgat ttgcaaaatc
     9301 agacttatcg ggtaattgag aatggagttg aagtatcatt ttgaagcctt gatatggtgg
     9361 ataaaatagg gtttttattt tggaaaacgt ttcctttgtt ttcaaattgc taaaaaagtg
     9421 gtacaatata ggatagctta ctattatctg aatcagctga tttggagaga aaggattcat
     9481 tttgaaatca ataggcttta ttgaaaagct gaaggggttg tctagtaaag agctgatttt
     9541 attgggaatt atcctaagta tctttttacc cttttatctt tttgtagttg tactctgttt
     9601 atatattatc agtttgattt ttacaggaga catgaaaagt attcttcaga aaatggggga
     9661 gcatccgatg ctgcttcttt ttcttagcta tagtactgtt atatccattc ttgcacaaaa
     9721 ttggatgggt cttgtggctt cagtaggaat gtttctattt actattttct ttttgcacta
     9781 tcagtcgatt ttatcccata aattctttcg attgattttg cagttcgtct tgtttggtag
     9841 tgtcttgtca gctgcttttg ccagtttaga acatttccaa attgtgaaga aatttaacta
     9901 tgcttttctt tcacccaata tgcaggtgtg gcatcagaac cgggcagaag tgaccttctt
     9961 taatcctaat tattatggaa ttatttgttg tttctgtatt atgattgctt tctatctgtt
    10021 tacaacgacc aagttgaatt ggttgaaagt attctgtgtg attgcaggct ttgttaatct
    10081 ctttggtttg aactttactc aaaatcgaac tgcctttcct gctattatcg ctggagcaat
    10141 tatctatctc tttacgacta ttaaaaactg gaaggccttt tggcttagta ttggggtctt
    10201 cgcgattggt ttgagtttcc tcttttctag tgatttggga gttcgaatgg gtactttaga
    10261 ctcttctatg gaagaacgca tttctatctg ggatgctggg atggccttgt ttaagcaaaa
    10321 tcctttttgg ggtgaagggc cattgaccta tatgcactct tatcctcgga tacatgctcc
    10381 ttatcatgaa catgcccaca gtctttatat tgatacgatt ctgagttacg gaattgtggg
    10441 taccatttta ttagttttgt cttctgttgc tcctgttcgc ttgatgatgg atatgagtca
    10501 ggagtcgggg aaacgtccga ttatcggcct ttatctatct ttccttacag tggttgctgt
    10561 gcacggaatt tttgacttgg ctctcttctg gattcagtca ggctttattt tcttgctagt
    10621 tatgtgcagt attccattgg agcatcgaat gttggtatcg gacatgacgg attaagtttt
    10681 ataagtttga aatcttctac cttgggtagg agattttttt atacgatggg catgtcgtgc
    10741 atctgaggtg taagtcctct gtagggatcc actaccggtg aatacaatag cgctccccaa
    10801 gcctgactat cgtgaggtag cggattaaaa tggtctgggg atagatcgtt ttaagtctga
    10861 cgcaggaaat aagaattgtc agagaaagca atagtgaaat cgtaggctat gaatagaaac
    10921 gtgatagcga ggagcatata gtggataagg tagcgagaaa ttttaaagta taaaagatag
    10981 tcttaatcta tatatgtaaa tcacaaaagt aattgaattc ggaataaggt tggtgtgaaa
    11041 agacatagta aactgaatct tgaatactag aatgatactt ctacaatatt gttataattt
    11101 aatttgaatt ccaaaatcac attgttccgt ccgtatttca ttttactgta tgtcttccta
    11161 aactccaaag tttctgcgtc aaatttccta ttttcactgt agtctttgac acttcgaacg
    11221 acaatttgaa tcatatattc aaaaaaaaat gaaaaatttg tgccaacaag cctaaatatt
    11281 ctgaaaattt gtttgatttt taatggataa tgtgatataa tggttgtcaa tctataattc
    11341 acataaacag aggagtagaa aatgaaaaaa aatcgtgtat ttgctacagc aggtcttgtt
    11401 ttattagcag caggtgtact tgcagcatgc agttcttcaa aatcatctga ttcatcagcc
    11461 cctaaagctt atggctatgt ttatacagca gacccagaaa ccttggacta cctgatttca
    11521 agtaaaaata gtacaacagt agtgacttca aatgggattg atggtttatt cactaacgat
    11581 aattacggta atcttgctcc tgcagttgca gaggattggg aagtctctaa ggatggtttg
    11641 acctacactt ataagattcg taaaggggtt aaatggttta cctctgatgg agaagaatat
    11701 gcagaggtga cggctaaaga tttcgtgaac ggtttaaaac acgcagcaga taaaaaatca
    11761 gaagctatgt atttagctga aaattcggtt aaaggcttgg cagattatct atcaggaact
    11821 tcaacagatt tttcaacagt tggtgtcaag gcggttgatg attatacgtt acaatacact
    11881 ttgaaccagc ctgaaccgtt ctggaactct aagttgacct attctatttt ctggcctctg
    11941 aatgaagaat tcgaaacatc aaaaggaagc gattttgcta aaccaacaga tccgacatcc
    12001 ttgctttata atggtccatt cttgttgaaa gggttgactg caaaatcttc tgtagagttt
    12061 gtaaaaaatg agcaatattg ggataaagaa aatgtccacc tagatactat caatctagct
    12121 tactatgatg gatcagatca ggagtcgcta gagcgtaact tcactagtgg agcttatagt
    12181 tatgcccgtc tttaccctac cagctccaac tattctaagg ttgcagaaga atacaaggac
    12241 aatatctatt acacacaatc aggctctggg attgctggtc tgggtgtgaa tattgatcgc
    12301 caaagttaca actatacttc taaaactaca gattcagaga aagtagctac taagaaggca
    12361 ttgcttaaca aagatttccg tcaagccttg aattttgctc ttgatcgctc agcttactca
    12421 gctcaaatca atggtaaaga tggagcagct ttagcagttc gtaatttatt tgtaaaacca
    12481 gactttgttt cagctggtga gaagaccttt ggtgatttag tcgctgctca acttcctgct
    12541 tatggtgatg agtggaaagg tgtgaattta gctgatgggc aggatggttt attcaatgtt
    12601 gacaaggcca aggcagagtt tgcgaaagct aagaaagctt tagaagcaga cggcgttcag
    12661 tttcctattc atctggacgt tccagtagac caagcatcaa aaaactacat atctcgtatt
    12721 cagtccttta aacaatctgt agaaacagtt cttggtgttg aaaatgtcgt tgttgatatt
    12781 caacaaatga caagtgatga attccttaat attacttact atgctgccaa tgcttcatct
    12841 gaggattggg atgtatcagg aggagtttca tggggtccag actatcaaga cccatctact
    12901 tacctggata ttttaaaaac aactagcagt gaaactacaa aaacatattt aggatttgat
    12961 aatccaaata gcccttcagt agttcaagtt ggtttgaaag aatacgataa attagttgat
    13021 gaagctgcca gagagacaag cgacttgaat gtccgttatg aaaaatatgc agcggctcaa
    13081 gcatggttga cagatagttc actctttatt cctgctatgg cttcttctgg tgcagcacca
    13141 gtgctttcac gaattgttcc atttactgga gcttctgcgc aaacaggctc taaggggtca
    13201 gatgtttact tcaaatattt gaaattacaa gataaagtgg tgactaagga agagtatgaa
    13261 aaagctcgtg aaaaatggtt gaaagaaaaa gctgaatcaa atgagaaagc tcaaaaagaa
    13321 ttggcaagtc atgtgaagta aataatttct aatagaactt tctctccatg aggagaaggt
    13381 tcttttggga tttttaaagg aaataatatg aaaaaatata tttttatgcg tgttttgcgg
    13441 tcattggttt cgattttctt agtaacgact ttgacctaca cgattatcta taccttggtt
    13501 cctcgaaaat tgattttcaa gcaggatcct aactataata aaattgcgac aacggctgat
    13561 aaacgtgata actatgaaaa tactgtgttt gagcgtatgg gctacattga gtattacgat
    13621 actaaagagt tgcaagaaaa ggcaagtagc atggattctt ctgtaacagt agaagcaaat
    13681 gcgaccaata aagctattta tgaaaagtac atcaatcaat taggtcatgg ttggactttg
    13741 ggagaattta ctgaaagtgg tcaattctat gctactcgtg aaattccaat ttttgaacgt
    13801 gtttttcact tctatgctaa cttgattgac attgaccata caaataaaat ccaagaccct
    13861 gaaaatccag acttgaaacg ctaccttcgt tttgaaaatg atccagctat cggatggtca
    13921 ttggtcggtt caggaactaa acataaatat ctcttgtact ttaacagtca gttcccattt
    13981 gttcatcaaa actttgtgaa cttgaattta ggtgactctt acccaaccta tgctaataca
    14041 ccagttcttc aggttattac tcaaggtcaa ggacaaacca aaactgccca agttcagttc
    14101 ccaacaggta agaaaacgtc ttctgtaaat atttactcaa gaacctacaa gtcacctagt
    14161 caggctgact ctcgtgaagt agctagctat gggaaagatg atccttatac agcgactgaa
    14221 agtaattacc aatatccatc tatgattgtc agctctgcta ttactggttt gattggtttg
    14281 gttcttgcct atgctcttgc cgtgccactt ggttcagcca tggctcgttt caagaacact
    14341 tggattgata gcctctcaac agggactttg accttcttgc ttgctcttcc aacgattgcc
    14401 ttggtttaca tcgttcgatt gattggatca tctattgccc ttccagattc attccctatc
    14461 ttgggagctg gagattggcg ttcttacgtt ttaccagcag tcatccttgg tttgttgggt
    14521 gctcctgtta cagccatttg gattcgtcgt tacatgattg acttgcaatc tcaagacttt
    14581 gttcgtttcg ctcgtgcaaa aggtttgtct gaaaaagaaa tttcaaacaa acacatcttt
    14641 aaaaatgcca tggttccgct ggtttcagga attcctggtg ccattattgg ggttatcggt
    14701 ggtgcaaccc ttactgaaac agtcttcgcc ttcccaggta tgggtaaaat gttgattgac
    14761 tctgtaaaag catctaataa ctctatggtc gttggtcttg tcttcatctt tacatgtatt
    14821 tctatcttct cacgtctttt gggagatatt tggatgacta ttattgaccc acgtattaaa
    14881 ttgactgaga aaggaggcaa ataatgtcta caatcgataa agaaaaattt cagtttgtaa
    14941 aacgtgacga ttttgcctct gaaactattg atgcgccagc atattcttac tggaaatcag
    15001 tgtttaaaca atttatgaag aaaaaatcaa ctgtagtcat gttgggaatc ttggtagcca
    15061 tcattttgat aagtttcatc tacccaatgt tttctaagtt tgatttcaat gatgtcagca
    15121 aggtaaacga ctttagtgtt cgttatatca agccaaatgc ggagcattgg ttcggtactg
    15181 acagtaacgg taaatcgctc tttgacggtg tctggttcgg agctcgtaac tccatcctca
    15241 tttctgtgat tgcgacagtg attaacttgg ttatcggtgt ttttgtcggt ggtatttggg
    15301 gtatttcaaa atcagttgac cgtgtcatga tggaagttta caacgtcatc tcaaacatcc
    15361 cacctctttt gattgttatt gtcttgactt actcaatcgg agctggattc tggaatctga
    15421 tttttgccat gagcgtaaca acatggattg gtattgcctt catgatccgt gtgcaaatct
    15481 tgcgctatcg tgacttggaa tacaacttgg cgtcacgtac tttgggaaca ccaaccttga
    15541 agattgttgc caaaaatatc atgcctcaat tggtatctgt tattgtgaca accatgactc
    15601 aaatgcttcc aagctttatc tcatacgaag ccttcttgtc tttcttcggt cttggattac
    15661 cgattacagt gccaagtttg ggtcgtttga tttcggatta ttcacaaaac gtaacaacca
    15721 atgcttactt gttctggatt ccattgacaa cccttgtctt ggtatccttg tcccttttcg
    15781 tagttggtca aaacttagcg gatgctagtg atccacgtac acatagatag gagtagaaat
    15841 gacaaaagaa aaaaatgtaa ttttgactgc tcgcgatatt gtcgtggaat ttgacgttcg
    15901 tgacaaagta ttgacagcca ttcgcggcgt ttcccttgaa ctagttgaag gagaagtatt
    15961 agccttggta ggtgagtcag gatcaggtaa atctgttttg acaaagacct tcacaggtat
    16021 gctcgaagaa aatggtcgta ttgcccaagg tagtattgac taccgtggtc aggacttgac
    16081 agctttatct tctcacaagg attgggaaca aattcgtggt gctaagattg cgactatctt
    16141 ccaggaccca atgactagtt tggaccccat taaaacaatt ggtagtcaga ttacagaagt
    16201 tattgtaaaa caccaaggaa aaacagctaa agaagcgaaa gaattggcca ttgactacat
    16261 gaataaggtt ggcattccag acgcagatag acgttttaat gaatacccat tccaatattc
    16321 tggaggaatg cgtcaacgta tcgttattgc gattgccctt gcctgccgac ctgatgtctt
    16381 gatctgtgat gagccaacaa ctgccttgga tgtaactatt caagctcaga ttattgattt
    16441 gctaaaatct ttacaaaacg agtatcattt cacaacaatc tttattaccc acgaccttgg
    16501 tgtggtggca agtattgcgg ataaggtagc ggttatgtat gcaggagaaa tcgttgagta
    16561 tggaacggtt gaggaagtct tctatgaccc tcgccatcca tatacatgga gtctcttgtc
    16621 tagcttgcct cagcttgctg atgataaagg ggatctttac tcaatcccag gaacacctcc
    16681 gtcactttat actgacctga aaggggatgc ttttgccttg cgttctgact acgcaatgca
    16741 gattgacttc gaacaaaaag ctcctcaatt ctcagtatca gagacacatt gggctaaaac
    16801 ttggcttctt catgaggatg ctccaaaagt agaaaaacca gctgtgattg caaatctcca
    16861 tgataagatc cgtgaaaaaa tgggatttgc ccatctggct gactaggagg aaggaaatgt
    16921 ctgaaaaatt agtagaaatc aaagatttag aaatttcctt cggtgaagga agtaagaagt
    16981 ttgtcgcggt taaaaatgct aacttcttta tcaacaaggg agaaactttc tcgcttgtag
    17041 gtgagtccgg tagtgggaaa acaactattg gtcgtgctat catcggtcta aatgatacaa
    17101 gtaatggaga tatcattttt gatggtcaaa agattaatgg taagaaatcg cgtgaacaag
    17161 ctgcggaatt gattcgtcga atccagatga ttttccaaga ccctgccgca agtttgaatg
    17221 aacgtgcgac tgttgattat attatttctg aaggtcttta caatcaccgt ttatttaagg
    17281 atgaagaaga acgtaaagag aaagttcaaa atattatccg tgaagtaggt cttcttgctg
    17341 agcacttgac tcgttaccct catgaattct caggcggtca acgtcaacgt atcggtattg
    17401 cccgtgcctt ggtcatgcaa ccagactttg ttattgcaga tgagccaatt tcagccttgg
    17461 acgtttctgt acgtgcccaa gtcttgaact tgctcaaaaa attccaaaaa gagctcggcc
    17521 tgacctatct cttcatcgcc catgacttgt cggttgttcg ctttatttca gatcgtatcg
    17581 cagttattta caagggtgtt attgtagagg ttgcagaaac agaagaattg tttaacaatc
    17641 caattcaccc atatactcaa gccttgcttt cagcggtacc aatcccagat ccaatcttgg
    17701 aacgtaagaa ggtcttgaag gtttacgacc caagtcaaca cgactatgag actgataagc
    17761 cgtctatggt agaaatccgt ccaggtcact atgtttgggc gaaccaaacc gaattggcac
    17821 gttatcaaaa aggactaaac tagtaatggt tttataattt ccatgtcaat ttttatggga
    17881 attataaaac tttttttgtt ggactgattt gaaaaacttt gaaagcttcc tgaaagaatt
    17941 ttcgaaaaat tttaaaaaat tctgaaatat tattgacagg tgatgaaaaa ggtggtagga
    18001 taggaagcat caaaaaagaa agcagaaaaa gaaatgaata agagacaagc cgtaactatg
    18061 aatcaaaact tttactttag ctactttaga tagtgtttgt agacatgtca ccatggatgc
    18121 aaacagttca agcaatttgt ttgtatctat gtggctaaga tttttgattg tggtccatat
    18181 agatgaatat ctaaatggac tagctaagtt gtaacttgtt aggttatttc aagtatccgt
    18241 ttagatagta tctaggcggt tttttgtttt atcttttctg agaaggagtt tcattatgaa
    18301 agttgttcga aaatcactag ccccctcttg gtagtggggc tcctcttgac ttctctgatc
    18361 agtttgcatc agttgaaggc agataagaaa aagatgtctt tcgtatcggt atttcgcagt
    18421 ttattaccca ccagtcctta gacgctacta gagaaggatt tgtggatgag ctggccaaac
    18481 aaggctatgt tgagggggaa aatattgaga ttgatttgca aaatgcacag ggagaacaaa
    18541 gaaatctaaa aacgatttcc cagcaactag cagaatccag cgatgtcgtt ctagccatcg
    18601 caaggccttc tgctcagagc ttggccaata cgacgcaaac gacaccagtt atcttttcag
    18661 ctgtaacaga cccagtcagt gccaagttgg ttgagtcaag agaacatcct gggggcaatg
    18721 taactgggac aagcgatcag tcatcagatg ccatttcaac ccaaatcaat ttgataaaga
    18781 aagtgttgcc aaaggctaaa acgattggaa tcctctatac tcagagcgag cccaattcgg
    18841 ttgtttaaaa ggatgaagct aagcgacttc tgaaagaaaa aggctttacc gttgttgaaa
    18901 aaacaatctt ggacagtaat aacgtcaagg cggcagcaga gagtttgatg gcagaggtgg
    18961 atatggtttt tgtcccaact gataatatca tttcgtcaac catggaaaca gttaagcagg
    19021 tttctattaa acacaaggtt ccagtattcg gtggttcaac agaaatgatt gctgttggtg
    19081 gcttgtataa ctacggaacc aattatgaag aattgggacg gcagacagct cgcatgctga
    19141 ttcgtgtttt aaaaggtgag aaaccagaaa atatagcagt tgagttgcct gaaaaactgg
    19201 aattgcatac caatcaagaa atggcagatg cattgggaat tgatattagt aagttagaag
    19261 gcaaggaata aggaggatta agatgaattt tgtgttatct agtttatcag aaggtttgtt
    19321 gtggtcgatt atggcaattg gggtctactt gactttccgt attttgaata ttgcggatat
    19381 gactgctgag ggagcctttc ctctgggggc agcagtcgtt gtatcacaga tacaggcagg
    19441 ggcaaatcct tggcttgcga ctttacttgc tttggtggca ggtatggtag caggtcttgt
    19501 atcaggaatg ctccacacca atatgaaaat cccagctctc ttgacaggga ttgtgacctt
    19561 gacagggctc tattcaatca atattaaaat tatgggcagt gtacccaatc tttccttggg
    19621 agattctgca accgtcttta aacagttggc gagcttgggt ctgacaaatg aaggagctgt
    19681 tttctcactt agtttagtct gtctcttact tgtttggtct tgaccctttt gatgaaaaca
    19741 gagattggtt tggtcttgcg ttcgactggg gacaatatcc cgatgagtga ggccaatgga
    19801 gtcaatgtaa acaccatgaa gattgttggt tacatgattt caaacggttt gattgcccta
    19861 tgtggttcct tgtttgccca aaatgatgga ttttcagatg tgacttctgg gacaggaacc
    19921 attgttgttg gtttgagctc ggaagtcttg atacacgact tgaccattgg aggccactta
    19981 ttatccatcg gaatcggtgc tattgtttac cgtttgatta ttttaaatat ctatgaaatt
    20041 ccaaatctag atcaaaactt ggtacgtctc tttaatgcaa tcttgctcgc tttggtttta
    20101 tttgcaccag aattgcaaaa gagattaaag attcgtggtc tgaaattgag aaatgaatag
    20161 gaggagaaag ttatggcaag tttgttaaca cttgaaaata ttcacaagac atttgaagca
    20221 gggacggtca atgagaacca tgtcctcaaa ggattagatt tagaggttga agagggagat
    20281 tttatctctg tgattggtag aaatggagca ggaaaatcca ctttgatgaa tatcttggct
    20341 ggtaatctat cggtggacga aggggacctt ctactggcag ggaaatccat taaacatctg
    20401 agtgtcagaa agagagccaa ggatattgcc cgtgtttttc aagatcctaa gatgggaaca
    20461 gcttctcgtt tgacgattga ggagaatatg gctattgcct tgagacgtgg gcaaaagaga
    20521 gggcttggtt ggggcgtgaa ggagaaggat agaatccagt tccaagaggc cttgaaggag
    20581 ttgaatattg gtcttgaaaa ccgcttaaaa gtagatactc aatatctctc aggaggacaa
    20641 agacaggctt tgaccctagt catggcagct ctggtgaaac tcaaactttt gcttttggat
    20701 gaacatactg cggcacttga cccgaaaacc agtcaaatgg tgatggactt gacgcaaaag
    20761 attgtggagt accatcagtg gacgactttg atgattaccc atgatatgaa tcatgcgatt
    20821 gagtacggca atcgtctcat tatgctctat caaggcaaga tagtggtgga tgtcaaggga
    20881 gaagagaaaa agcatctgac agttgaagac cttatgcatc tcttccagaa aaatagtggc
    20941 caaagtctgg tcagtgatga attagttttg ggataaagaa aaaggctgag atctggtgtc
    21001 tcagtctttt atttcttgcg ttttgcaaaa tctacaaatc taaatttttc taacttatgg
    21061 cgactttcgg taaactgaaa ttggcgcccg tcttggagat agacttttga tttaatcgaa
    21121 acgacataag ggtctttgcc aatgtccatg agaatcttgt ctcggtcgct tgagtggtca
    21181 atggtgattt ccttctgagc ataatcaata aggagtttga ggccattttc tatataagaa
    21241 tagatagact gctcagcaat ttggcgagtg agatttggga tgagttccat atccagatag
    21301 tctgtatcca gaacggatac cagatcatcc accacacgct ggcggaccac cttccaaacc
    21361 atccgaaact ctgggaaacc ggttatcagt gaggattttt tatcaataat aatcttgtcc
    21421 agactgacca cgttggtttt agagcgcagt ccaagttctt taactagttc ttggtagctg
    21481 gttaggttgg atacagggaa attgacggtt tcttctttga cgacttgaga accttgccct
    21541 cttatctttt tgatcaatcc ttcctcttgg aggagagaca gggcctttcg gacggtatca
    21601 cgactcactt gatattgctc cataaggtcg tgctcgctag gaaggaaatc tccgacagcg
    21661 taagtctcgt tttgaatggt ttcttggatt tgcttaaata attgttggta tttcttcatt
    21721 ttgcctgctt aaataggttt tcagtctagt ttaatgaaca cctgtatcta ttttaccata
    21781 caagtgctag aaaatttaca aaaaaacacc ctttttatac caaacaagtt gcagacaagt
    21841 ttggtatcgt ttacaatata cttatcaaat caaacttgct ttgacaagta taaggagaat
    21901 caaatgggaa aatttgaaca agaagccaaa gatctgcttc aggcaattgg aggcaaagaa
    21961 aatgtgactg ccgtaactca ctgtgcgaca cggatgcgct ttgttttagg agatgataag
    22021 aaggctaatg ttaaagctat cgagtcaatt ccagctgtta aaggaacttt tacaaatgca
    22081 ggtcaatttc aggtaatcat tggaaatgac gtgcccatct tttataatga ttttacagcc
    22141 gtttcaggta ttgagggtgt ttccaaagaa gcagccaagt ctgcagctaa gagtaatcaa
    22201 aacgtggtcc aatgtgttat gaccactctg gcggagattt ttactccgat tattccagcc
    22261 ttgatagtcg gaggattgat cctcggtttc cgtaatgtct tggaaggtgt ccattggtcg
    22321 atgttggatg gcaagaccat cacagaatcc tctcagtttt gggcaggggt taatcacttc
    22381 ctttggttgc ctggtgaagc tatcttccag ttcttaccag tagggattac ttggtctgtt
    22441 tctcgtaaga tgggaaccag ccaaattttg ggaattgttc tcggaatctg tttggtatcg
    22501 cctcagttgc tcaatgccta tgcggttgct tcaacgccag cagctgatat cgcggcaaac
    22561 tgggtttgga attttggcta ttttactgtt aatcgtatcg gttaccaagc ccaagttatc
    22621 ccagccttgc ttgcaggttt gagtctgtct tatcttgaaa tcttctggcg caagcatatc
    22681 ccagaagtca tttctatgat ttttgtacct ttcttgtcat tgattccagc cttgattttg
    22741 gctcatactg ttttgggacc aatcggttgg acaattggac aaggactttc atcagttgtc
    22801 ttggcaggtt taactggtcc agttaaatgg ctcttcggtg caatttttgg tgccctctac
    22861 gctccatttg tcatcacagg tctgcaccat atgaccaatg ccattgatac acaattgatt
    22921 gcggatgctg gtggcactgc cctatggcca atgattgctc tttctaatat tgctcaaggc
    22981 tcagccgtgt ttgcctatta tttcatgcat cgccatgatg agcgtgaggc tcaggtttca
    23041 cttcctgcaa ccatttcagc ctatctcggt gttacagaac cagctctttt tggggttaac
    23101 gtaaaatata tttatccatt tgttgctggg atgactggtt cagcccttgc aggcatgtta
    23161 tccgttactt ttaatgtaac tgcggcttct attggtatcg gtggtttgcc aggtattctc
    23221 tctattcaac ctcaatacat gctgccattt gcaggaacta tgctagttgc gattgttgtt
    23281 ccaatgctct tgactttctt cttccgcaag gctggtctct ttacaaaaac agagggcgat
    23341 acgaacttgc aggcagaatt cgttgctcaa gaagaagcag aatttgtgaa ccatgaacca
    23401 gtagaactta cttcggtaga aattatcagc ccactaactg gccaagtgaa agaattgagt
    23461 caagcgacgg atcctatttt tgcatcaggt gtcatggggc aaggtctggt cattgaacca
    23521 agccaaggtg agttgacctc tccagttaat gggacagtga cggttctttt ccctaccaag
    23581 catgccatcg gcattgtctc tgacgaggga gttgaattgc tcatccacat cggtatggat
    23641 acagtaggtc ttgatggcaa aggttttgaa agtcttgtag tccaaggaga tcacgttaca
    23701 gttggtcagc aactgattcg ttttgatatg gatgtcatta aggctgcagg tctggtgaca
    23761 gaaactcctg ttatcatcac caaccaagat gcttatacag cgactattcc cggaacttat
    23821 ccgacaacga tccaagctgg agcatctctc atggtcgcta cacgaatcta atactcttcg
    23881 aaaatctctt caaaccacgt cagctctatc tgcaacctca aaatagtgtt ttgagcaacc
    23941 tgtggctagc ttcctagttt gttctttgat tttcattgag tataattgaa atagcacaaa
    24001 tagggacgga agactgcttc ctccctttta tcagaaaagg agaaacagat gacacttgat
    24061 aaaggaaaag tagtctatca aatctatcca aaatcttaca aagacaccac tgaaaacggt
    24121 attggggatt tccgtgggat tatcgaaaaa attccctatt tagccaaatt aggtgtggat
    24181 atggtctggc tcaatccatt ctatccaagc cctcaacggg ataatggtta cgatatttca
    24241 gattatatgg cagtggatcc tctttttggt gatatggctg attttgagga aatggtgtgt
    24301 gtcggtaaag agcacaagat tgactttatg ctggacatgg tacttaatca ttgttcgaca
    24361 gagcatgaat ggtttcagaa agccctagct ggtgataagt attatcaaga ctttttcttc
    24421 atccaagacc aaccaacaga ttggcagtct aagtttggtg gttctgcatg ggcgcctttc
    24481 ggggatactg ggaaatacta tcttcaccta tttgatgaga cccaggctga ccttaactgg
    24541 cgcaattcca atgtccgtaa ggagcttttc aaggttgtta atttctggcg cgacaagggt
    24601 gtcaaaggtt ttcgatttga tgtgatcaat ttgatcggta aggacgaggt ttcagtggac
    24661 tgtcctgaaa atgaagggaa gccagcttat acagacaaac ccatcgttca taactatttg
    24721 cgtatgatga accaagccac ttttggatct gacgatagct ttatgacagt tggggaaatg
    24781 tcttctacca ccatggaaaa ctgtgtcctc tattcgtcgc ctgatcgtca ggaattatcc
    24841 atgaccttta attttcatca cctcaaggtg gactataagg atggacaaaa gtggaccttg
    24901 gctccctttg attttgaaga gttgaagagt ctttaccata gttggggtaa ggaaatgagt
    24961 gataaagacg gttggagtgc cctcttttgg aacaatcacg atcaaccacg tgccttgaac
    25021 cgttttgtcg atattcaaaa cttccgcaag gaaggagcca ctatgctagc agccagcatt
    25081 cacctgtcac gtgggacacc ttatatctac atgggtgagg aaatcgggat gattgaccca
    25141 gactatgatt ctatggctga ttacgtggat gtcgaatcgc ttaatgccta tcagatgctc
    25201 ctagaagaag gaaagagtca gcaagaagcc ttccagatta ttcaagctaa gtcgcgtgat
    25261 aattcacgca ttcccatgca gtgggatgct tcggaaaatg caggattttc aacaggcact
    25321 ccttggttga aagctggtaa atcctataaa gacatcaatg tagaaaatga aatccagggt
    25381 ccgattttta ccttctatca agacttgatt cgactgcgta aggaaatgcc aatcatttca
    25441 gaaggaagtt acaaaccagc ctttgaagat agcaaacaag tctacgcttt tgaacgccag
    25501 tttgaggatc aaaagttact agtgctcaat aacttttatg ctaaagaagt ggaaatcgac
    25561 ttgccagcag tctaccaaaa tggacagatt ttgatttcaa actatgaaga tgcagaagtg
    25621 tctgagaaaa ttctactaaa accctatcaa acactggcta tttatgtaaa ttaaacttag
    25681 caaggagacc tctttttcag aaaagcaggg ttctttttgc tgtctattcc atccttgaaa
    25741 gtgtagaaca aactggtcag ggtggctagt ttgtggtata atgaaaggga ttcaaaaaga
    25801 aacaggagaa aaatgatgga tttactttta gcaattgtat tgattgtgct agcttttcta
    25861 ggaggagctc ttggaggaat gtacttggtt cgtaagcaaa tcgaaaaaga atttgctgac
    25921 aacccacgtt tgaatgctga agcagttcgt actcttttga gtgcaaatgg tcaaaaacca
    25981 agcgaagcta aggtacaaca agtttaccac caaatcatcc gccaacaaaa ggcagccctt
    26041 gctaacaata aaaagaaaaa ataaataagg aaaagtctgg gatgaaagtt ccagacttct
    26101 cactatgttg gttatggttt agggatgaga ctttttcctt gcattctatt gatatttgat
    26161 tatgattaag agagaggtag ttgacattct atcaagctgt cggtcagttc gttcagtaca
    26221 aggaatcata atgaacgatc aatcagaaaa aagactagaa agaagactgt atggataatc
    26281 gaccaattgg ttttttggat tcgggtgtcg ggggcttgac cgttgtgcgc gagctcatgc
    26341 gccagcttcc ccatgaagaa atcgtctata ttggagattc ggcgcgggcg ccctatggcc
    26401 cccgtcctgc tgagcaaatt cgtgaatata cttggcagct ggtcaacttt ctcttgacca
    26461 aggatgtcaa aatgattgtc attgcttgta acactgcgac tgcggtcgtc tgggaagaaa
    26521 tcaaggctca actagatatt cctgtcttgg gtgtaatttt gccaggagct tcggcagcca
    26581 tcaagtccag tcaaggtggg aaaatcggag tgattggaac gcccatgacg gtacaatcag
    26641 acatataccg tcagaaaatc catgatctgg atcccgactt acaggtggag agcttggcct
    26701 gtcccaagtt tgctcccttg gttgagtcag gtgccctgtc aaccagtgtt accaagaagg
    26761 tggtctatga aaccctgcgt cccttggttg gaaaggtgga tagcctgatt ttgggctgta
    26821 ctcattatcc actccttcgc cctattatcc aaaatgtgat ggggccaaag gttcagctca
    26881 tcgatagtgg ggcagagtgc gtacgggata tctcagtctt actcaattat tttgaaatca
    26941 atcgtggtcg cgatgctgga ccactccatc accgttttta cacaacagcc agtagccaaa
    27001 gttttgcaca aattggtgaa gaatggctgg aaaaagagat tcatgtggag catgtagaat
    27061 tatgacaaat aaaatttatg aatataagga tgaccaggac tggtatgttg ggtcttatag
    27121 tatttttggt ggcgttaaca gtttgagcga ctataagaca gattttcctc tgtttgaatt
    27181 ctccaaaata tttggagatg aagagtatgg tttcccgctt tcagttactg ttttacgcta
    27241 tggttctacc taccgtttgt tctcctttgt ggtagacatg cttaatcaag aaatgggacg
    27301 aaacttggaa gttattcaac gtcatggggc cctgctcttg gttgaaaatg ggcaactctt
    27361 gtatgtagaa ttgcctaaag aaggggtcaa tgttcatgat ttctttgaga caagcaaggt
    27421 cagagaaacc ttgttgattg cgactcgtaa cgaaggtaaa accaaggaat tccgagctat
    27481 ctttgataag ttaggctacg atgtggaaaa tcttaatgac taccctgacc tgcctgaagt
    27541 agcagaaaca ggtatgacct ttgaagaaaa tgcccgcctt aaggcagaaa ccatttctca
    27601 attaacgggc aagatggttt tggcagatga ttctggtctc aaagtcgatg tccttggtgg
    27661 cttaccaggc gtctggtcag ctcgtttcgc aggtgtggga gcaactgacc gtgaaaataa
    27721 tgccaaactc ttgcacgaat tggccatggt ctttgaactc aaggaccgct cggctcagtt
    27781 ccacacaacc ctagtcgtag ccagcccaaa taaggaaagt ttagttgttg aagcagactg
    27841 gtcaggttat attaactttg aacctaaggg tgaaaatggc tttggctatg atcccctctt
    27901 ccttgtagga gagacaggtg agtcatcagc tgaattaacc ctggaagaaa aaaatagtca
    27961 atctcaccgt gccttagccg ttaagaaact tttggaggta tttccatcat ggcaaagcaa
    28021 accatcattg taatgagcga ttcccatggc gatagcttga ttgtggaaga agtccgtgat
    28081 cgctatgtgg gcaaagtcga tgccgttttt cataacggcg attctgaact acgtccggat
    28141 tctccacttt gggagggcat ccgcgttgtt aaagggaaca tggacttcta cgccggctac
    28201 ccagaacgtc tggtgactga gcttggttcg accaagatta tccaaactca tggtcacttg
    28261 tttgacatca atttcaactt tcaaaagttg gactactggg ctcaggagga agaggccgct
    28321 atctgcctct atggtcactt gcatgtgcca agtgcttggt tggaaggcaa gatcctcttt
    28381 ctaaatccag gttctatcag tcaaccacga ggtaccatca gagaatgtct ctatgctcgt
    28441 gtggagattg atgatagtta cttcaaagtg gactttttga cacgagatca cgaggtgtat
    28501 ccaggtttgt ccaaggagtt tagccgatga ttgccaagga gtttgagact ttcttgttgg
    28561 ggcaggagga aacttttttg acccctgcta aaaatctagc tgtgttgatt gatacccaca
    28621 atgcggatca tgcgaccctc ttgctcagtc agatgaccta tacccgtgtt cccgttgtga
    28681 cagatgaaaa acagtttgtt gggacgattg gactcagaga tattatggct tatcagatgg
    28741 agcatgactt gagccaagaa atcatggcgg atacggatat cgttcatatg acaaaaacgg
    28801 acgtagcggt tgtttcgcct gatttcacca ttacggaggt cttgcacaag ctagtagatg
    28861 agtccttctt accggttgtg gatgcagagg gtattttcca agggattatt acgcgcaagt
    28921 ccatcctcaa ggccgttaat gccctcttgc atgactttag taaggaatat gagattcgat
    28981 gccaatgaga gacaggattt cagccttttt agaggaaaag cagggcttgt ctgtcaattc
    29041 caagcagtcc tataagtatg atttggagca atttttagac atggtaggtg agcggatttc
    29101 tgagaccagt ctcaagattt accaagccca gctagccaat ctaaaaatca gcgcccagaa
    29161 gcgaaagatt tcggcctgta accaatttct atactttctc tatcaaaaag gagaggtgga
    29221 cagcttttac cgcttggaat tagccaaaca agctgaaaag aagacggaaa agccagagat
    29281 tctataccta gactcttttt ggcaggaaag cgaccatcca gagggccgct tgctagcgct
    29341 cttaatccta gaaatggggc ttttgcccag tgagatttta gccatcaagg ttgcggacat
    29401 caatctggat tttcaggtgt tgcgaatcag caaggcttcc caacagagga ttgtcactat
    29461 tcccacggcc ttgctttcag aattggaacc cttgatgggg cagacctatc tttttgaaag
    29521 aggagagaaa ccctattctc gtcagtgggc ctttcgtcag ttagaatctt ttgtcaagga
    29581 gaaaggtttt ccatccttat cagctcaagt cttacgtgaa cagtttattc taagacaaat
    29641 agaaaacaag gtcgatttgt acgaaattgc aaaaaaatta ggattaaaaa cagtcctgac
    29701 cttagaaaaa tatagataat ggatattaaa ttaaaagatt ttgaaggacc cctggacttg
    29761 ctcttgcatc tggtttctaa gtaccagatg gatatctacg atgtgcccat tacggaagtc
    29821 atcgaacagt atctagccta tgtctcaacc ctgcaggcca tgcgtctgga agtgacgggt
    29881 gagtacatgg tcatggctag tcagctcatg ctgattaaga gtcgtaaact ccttccgaag
    29941 gtagcagaag tgacagactt gggggatgac ctggagcagg acctcctctc tcaaatcgaa
    30001 gaatatcgca agttcaagct cttgggtgag cacttggaag ccaagcacca agaacgggcc
    30061 cagtattatt ccaaagcgcc gacagagttg atttacgaag atgcggagct tgtgcatgac
    30121 aagacgacca ttgacctctt tttggctttt tcaaatatcc tagccaagaa aaaagaggag
    30181 tttgcacaaa atcatacgac gatcttgcgg gatgagtata agattgagga catgatgatt
    30241 atcgtgaaag agtccttgat tggacgagat caattgcgct tgcaggattt gttcaaggaa
    30301 gcccagaatg tccaagaggt catcaccctc tttttggcaa ccctagagtt aatcaaaacc
    30361 caggagctga tcctcgtgca agaggagagt tttggagata tctatctcat ggaaaagaag
    30421 gaagaaagtc aagtgcctca aagctagact tgatagagag gaaagatgag tactttagca
    30481 aaaatagaag cgctcttgtt tgtagcgggt gaagatggga ttcgggtccg ccagttagct
    30541 gaactcctct ctctgccacc gacaggcatc cagcaaagtt taggaaaatt agcccagaag
    30601 tatgaaaagg acccagattc cagtttggct ttgattgaga caagtggtgc ttatagattg
    30661 gtgaccaagc ctcaatttgc agagattttg aaggaatact ctaaggcgcc tatcaaccag
    30721 agcttgtctc gggctgccct tgagaccttg tccattattg cctacaaaca gccgattacg
    30781 cggatagaaa ttgatgccat ccgtggggtt aactcgagtg gagccttggc aaagttgcag
    30841 gcttttgacc tgataaagga agacgggaaa aaggaagtat tggggcgccc caacctctat
    30901 gtgactacgg attatttcct agattacatg gggataaacc atttagaaga attaccagtg
    30961 attgatgagc ttgagattca agcccaagaa agccaattat ttggtgaaag gatagaagaa
    31021 gatgagaatc aataagtata ttgcccacgc aggtgtggcc agtaggagaa aagcagaaga
    31081 gctgattaag caaggcttgg tgacggttaa cggccaagtg gtgcgtgaac tagcaaccac
    31141 tatcaagtca ggcgacaagg tcgaagttga aggtcaacct atctacaacg aagaaaaggt
    31201 ctactatctg cttaacaaac cacgcggtgt gatttccagt gtgacagatg ataagggtcg
    31261 caagacggtt gtcgacctct tgcccaatgt caaagaacgt atttaccctg tgggtcgttt
    31321 ggactgggat acatcaggtg tcttgatttt gaccaatgat ggggacttta cagacgagat
    31381 gattcaccct cgtaatgaga ttgacaaggt ttatgtcgcg cgtgttaaag gtgtggccaa
    31441 taaggacaat ctccgcccct tgacccgtgg tcttgagatt gatggtaaga aaaccaagcc
    31501 agctgtttat gaaattctca aagtggaccc agtcaaaaat cgctctgtgg tgcagttgac
    31561 catccatgaa gggcgtaacc atcaggttaa aaagatgttt gaagctgttg gtctccaagt
    31621 agataagttg tctcggactc gtttcggaca cctagacttg acaggactcc gtccaggaga
    31681 atcccgtcgt cttaataaaa aagaaatcag ccaactacac accatggctg taactaagaa
    31741 ataatgaaac gaattttaat agcgcctgtg cgcttttacc aacgttttat ctcaccagtc
    31801 tttccaccct cttgtcgctt tgagctgact tgttccaact acatgattca ggctattgaa
    31861 aaacatggtt ttaagggggt attgatgggc ttggctcgga ttttacgttg tcatccctgg
    31921 tcgaaaacag gtaaggaccc cgttccagac cacttttccc ttaaacgaaa tcaagaaggg
    31981 gaatgaggtg gggtaaatag atttcaaaat gataaaaacg catcctatca ggtttgagtg
    32041 aacttgatag gatgcgtttt agaatgtcaa aattttatac tcttcgaaaa tcccttcaaa
    32101 ccgcgtcagc tttcatctgc aacctcaaaa cagtgttttg agcaacctgc ggctagtttc
    32161 ctagtttgct ctttgatttt cattgagtat taaattgagt ttgaagtggc ttatttcaaa
    32221 gctttttgta tgtcttcaat catgagtttt gttgattcaa gtccgcctcc gcttagatac
    32281 cagaggtctg gtgttagttg gataatctta ccatttttag cagcaggtgt ttcagcgata
    32341 agggcatttt ctaggacacc gtcgttgcta gagttgtccc caccgatggc aagggtacgg
    32401 ttgatgacaa agaggatgtc agggttgatt tctttgacac tttcaaagct gacttcttgt
    32461 ccgtggcgtg agtcttcaaa tgttgtatca gttggtttga atttcaaggt ttggtacaag
    32521 aaagagaaac gagatttggc accaaaggct gccatttttc cttcattaag gaggatcgca
    32581 agggcctttt tgtcagagct ttcattttta gtagcgactt tttggatgct cttgtctagc
    32641 ttggccaatt cttccttggc tttctgtgta ccagtttcgc cgaaggcact tgctaaggat
    32701 tcgatattag ccttggtaga agtccagtag tcgtccttgc ttgcttggaa gagaacggtt
    32761 ggggcgattt ctttgaattt gtctacgaat ttttgtgtac gtggtgaagc gataatcaaa
    32821 tcaggctcaa gggcggcgat agcttctaaa tcaggttctt tcatagaacc aacatttttg
    32881 acagttccca ctaggtcttt tagataagtc ggaacagttt ttgtaggcat tccgacgata
    32941 tttttttcaa atcctaaagc gcgaatagta tccgcagcgc cgaggtcaaa ggtcacaatc
    33001 ttttcaggaa ctttggaaag tttgacctcg tccagtgaac ttttaatggt tacctctgtt
    33061 ggagcagagc tactggtctc tgtctgacta gtgcttgagt ttgtactaca tgcaccaagt
    33121 aggagcaaga agctggccac tagggcagtg aaataaagtt taagggatgt tttcataatt
    33181 tctccttttt aaaatgtgat aacgatttag ggagtctctt aatcttattg actaagagac
    33241 tgaaggttct ctaacttgag cttttatgtt actagctata gatacagatc tttttgtcat
    33301 tgatatcagc tagcgtgatg ggaatctcat aaagttgact gagcaggtca gcctgcatga
    33361 tttgatcggt tcttcccttg ctaaagacct ggccgtcctt gaaggcgaca atttcatctg
    33421 catactgact ggccatgttg atatcgtgga ggacgatgat aatggtcttg ccgagttcct
    33481 ccaccagtcg tcgaagaatc tgcatcatgc tgacgctttg cttgatatcg agattgttga
    33541 gtggttcgtc cagcaagata aagtccgtat cctgggccag taccatagcg ataaagacgc
    33601 gctggagttg cccccctgac aggctattga tgtagcggtc ttttaagttg gtcagttcca
    33661 aatagttcag agtttctcgg attttttccc agtcttctga tctaagtcga cctcggctgt
    33721 agggaaaacg tccaaaactg accagttctt caacagtcaa tttggcttgg taattgattt
    33781 tctgttttag gatggttagt tcttgggcca gttcttgcga attccagctc tcgatttcac
    33841 gtcctttgat actgagaact ccctgatctt tcttggttag tctgctcatg atggagagga
    33901 gagtcgattt tccagcacca tttggaccaa taaaggctgt cagtttttga ggactgactt
    33961 caagcgaaat gccttgcaaa atatcctgtt tttgaatgga tttgtcaatg ttttccagtt
    34021 tcactgacga gccctcctat atagtaagat aaagaataag aagccaccca cactctcaat
    34081 gatcatactg atacgaattt ccagtgcaaa gactcgttca atcaaggctt gccccaaggt
    34141 taagctaata aatccaacca gaatggccac tataaagagt aacttgtgct gatagtcttt
    34201 gacaatcagg taggtgaggt tggccagcat aaagccgaag aaggccatag gtcctaccaa
    34261 ggcagtggcc gttgaggtca aaagcacgat tccccagagg agctctttct gttctttttc
    34321 aacatcgagt cccaatatct gagccgtttc tctttgcagg tgcaagacat ctagaacgac
    34381 tgcttttcga aagaaaaaga ttgtcaaagc gaggatgatc agagaaccga tggctaggat
    34441 ggaagtgtta agatgttgaa aggaggcaaa aagactattt tgcagtttat cgtattcgtt
    34501 tggatccatt aggacttgaa ggaaggtgct gatatttcga aagagacttc tgagcgctag
    34561 acagatcagc aggatgaaga ccaggtcttg cttcatcagt gtcttcaagt aaccttgtaa
    34621 ggcgagaaag aagagggact ggacaagaag taagactagg aattctaaga taggggattt
    34681 gccaagttga agaaacttgc tttcaaaaac cagtagtagg gtttgtagta ggacgtagaa
    34741 ggattcaatt cccaaaatac taggcgtcag gaagcgattt tccgtcaggg tttgaaaact
    34801 aatggtcgaa atcccagtcg cgatggctac caagagataa acgatgatct tttgggaacg
    34861 caacttccaa gcaaaggctg acaagtgagt gatgggccaa aagtagagaa gacaagctcc
    34921 gatggcaaga ataatgagaa tccagaagag cttggtatgt ttgcttttag tctgcatctt
    34981 ttcgtccccc tctccagaga agtaggataa agacgagact accgatgatt cctagcaaga
    35041 gactgacaga caactcatag ggcctaatca gaactcggga taggatatcg caagccagaa
    35101 ctagattggc accaaccagt gcgaccatga gtttggtttg acttagatta tctccatagc
    35161 gcttgcgaac aagattggga acgataactc cgagaaatgg taagccaccc acggtaatca
    35221 tggtgacgct tgtcgttagc gccaccagaa agagggccag tttttcaagt agggagtagg
    35281 aaatccccaa actctcgctg gtttctttcc ctagattcat gatggtgaag gtttgggata
    35341 atttccaaac ggttatcagg atgatgaggc ctaagaagag ccactcatac tgatgggtct
    35401 gaatcatgga gaaggagccc tgggtccagg cagtcatact ctgaaccaga ttgaaacgat
    35461 aggcgataac ttctgtgact gagccgataa tcccgctata gatgatccca atcagaggca
    35521 acatccacct ttcctttaca gtaaaaatgg tcataaaggc taggaagaag agggtgaata
    35581 ggatggatga aacaaaagcg aagagcatct tttgggtcag actagccgat ggaaagacaa
    35641 aaaggctcag caccattccc agtttggcgg cttcagtcgt tccaactgta ctcggtgcag
    35701 caaactgatt ttgggtaata gtctgcatga gaaggcctgc catactcata ctagaggcag
    35761 tcaggagaat actgatagtt cttgggagac gggactcttg aaagaggagc caggtctgct
    35821 ggtcgaaatc aaatagcttt ccccatgaaa aatcactggt cccaatgcta atagagagaa
    35881 agactaggag tagaagtaag ccaattaaat aatgagaaag tttcataccc cgtcctttca
    35941 tgtagatttg gtatcgaaag atacctgcgg atataaatgt aacattattt ttctaatctg
    36001 tcaataaaat ttctgacaat ttaataaata caacaaggag agagcaacaa gactttctcc
    36061 tttgttatcc tattctaaaa tgtttttacc ttaatctgat aaaataatat cttcgaggga
    36121 gtagctagcc gtccaatcaa gatattgttt agcttttgaa gcatctgcta ggacactggc
    36181 tgggtcacta gcacgtcgag caacaatctc gtgtgggatt ttttaattta gtaattcttc
    36241 agcagtttta aagatttctt tgatagtata gcctttttta gttcctaagt taaagatttg
    36301 agaagaactg tcttcttgaa ataggtagtt cattccttta acatgagcct atgcaaggtc
    36361 caagacataa atgtaatctc gaatacatga accgtcacgt gtatcgtagt catctccaaa
    36421 tatttttaag ctatcatgtt gtcccaatgc ggtcttgttg atatttggaa tgatgtgagt
    36481 tggatttttc acacgcagac cgtttgaagc atccatttca gccccagcaa cattaaagta
    36541 acggaaaata acatatttcc agtcgtagcg attggccatc cagtaaatca ttcgttcgcc
    36601 catcagtttt gtctctgcat aagggttgac agggtcgagc agggtatctt cagtcaccgg
    36661 cttgtcaata cagttatttc catagagaga agcagtcgaa gagaacatga ttttttgaat
    36721 gccaacttca gataagactt tgagaacttg gttcatacca gcaacgttgg cagtgaagta
    36781 tttacttgga ttttcaatac tttcgctcac aacaatttca cctgcataat ggaggacagc
    36841 atcaatctga ttttcttcta agtaagcctt taaggcgcta gcatcataaa catccagttc
    36901 tttaaagcta gcacgactat ccacagccgc tcgatttcct gtggagagat tatcgaggac
    36961 atgcacctta taaccagcat ttaaaagagc tttaacggta tgggagccaa tgtagctagt
    37021 cccacctgta acaagaattg ttttggtcat gattttttcc ttttctagtt ttgtactata
    37081 gtaaattgaa ataagatatg aacaactcta ttaggaaagt caaattaatt tctagaaatg
    37141 ttttagcagc tacagcgtac tattccaaac tcaaccaact atatatttaa agaaagaaga
    37201 aagggaagtc aactattttc tgtaaatttc atgaaaaatc taaacaactt tgatggtgta
    37261 ttgttttttg tttggaaata gatattcgag ttaattttgg aatgtttact agattttgca
    37321 ctacatgcaa gagaatacta tccttttcta agatagagca ggactaagat actaacttag
    37381 aaatccacct tcccactatc cttctcctat aaaaagtggt aaaatggatg aaagaaagaa
    37441 ggaactgaaa tgacaacatt attttcaaaa attaaagaag taacagaact tgctgcagtc
    37501 tcaggtcatg aagcgcctgt ccgtgcttat cttcgtgaaa agttgacacc gcatgtggat
    37561 gaagtggtga cagatggctt gggtggtatt tttggtatca aacattcaga agctgtggat
    37621 gcaccgcgcg tcttggtcgc ttctcatatg gacgaagttg gttttatggt cagcgaaatc
    37681 aagccagatg gtaccttccg tgtcgtagaa atcggtggct ggaaccccat ggtggttagc
    37741 agccaacgtt tcaaactctt gactcgtgat ggtcatgaaa ttcctgtgat ttcaggttct
    37801 gttcctccgc atttgactcg tggaaagggg ggaccaacca tgccagccat tgccgatatc
    37861 gtttttgatg gtggttttgc ggacaaggat gaggcagaaa gttttggcat ccgtcctggt
    37921 gataccatcg taccagatag ttctgcaatt ttgacagcca atgaaaaaaa tatcatctca
    37981 aaagcttggg ataaccgcta cggtgtcctc atggtaagcg agctagctga agctttatca
    38041 ggtcaaaaac tcggcaatga actctatctg ggttctaacg tccaagaaga agttggtctg
    38101 cgtggcgctc atacctctac aaccaagttt gacccagaag tcttcctcgc agttgattgc
    38161 tcaccagcag gtgatgtcta cggtggtcaa ggcaagattg gagatggaac cttgattcgt
    38221 ttctatgatc caggtcactt gcttctccca gggatgaagg atttcctttt gacaacggct
    38281 gaagaagctg gcatcaagta ccaatactac tgtggtaaag gcggaacaga tgcaggtgca
    38341 gctcatctga aaaatggtgg tgtcccatca acaactatcg gtgtctgcgc tcgttatatc
    38401 cattctcacc aaaccctcta tgcaatggat gacttcctag aagcgcaagc tttcttacaa
    38461 gccttggtga agaaattgga tcgttcaacg gttgatttga ttaaacatta ttaaaccata
    38521 agggaggtgg tagggatggt agaaccaaac ctagaaagcc ttataaaaga tctttacaat
    38581 catgctcgac atgatttgag tgaagattta gttgctgctc tcctagagac tgctaaaaaa
    38641 ctgcctacta caaatgagca attgcaggca gttcgtctct caggcctggt caatcgtgaa
    38701 ttgctcctaa atcccaaaca tccagcacct gagttgctca acttggctcg ctttatcaaa
    38761 agagaagaag ccaagtacag aggaactgcg acttctgcgc ttatgtatga ggaactcttt
    38821 aaaatgcttt gattccattg tggatcaaag cattttttgt aagatctatc tcgtgagcgt
    38881 tcaaatagta gtaacaagga atcatgagaa gtcagccgag cccatagtag tgaagaaact
    38941 tctgtaatgg aagtggagcg aagtgaggaa tcgtcaaacg gtaggggata ggctgtttga
    39001 agggtgctac gaaaaagata gggtaaggtg aaattatagc ggaatgaaat aagatatgaa
    39061 caaattgatt gaggaaatta aatgaattta tagaaatctt ttagcagtca tggtgtccta
    39121 ttccagtttc gaaatgctat aaatacgaac aaattgattg ggaaattcaa atcgctttct
    39181 atcaatgttt tagaagatac agtgctctag tctaacttca atatactata aaagaacaga
    39241 tggaagcaat tatgatttac ttctatcttt aaaataaatg gtctgatagg aaaaatgtgt
    39301 cccctcataa aatataggat agtacgaatg gaaggctttt gtagactgga ggacgaagga
    39361 gtttagaaac tctcgttaaa agttagttga gccggagtat ggtggtgtgg ataattatca
    39421 aaaattattt ctaaatcgaa atagttgaca gttagaacga tgagtgttac aattgtttta
    39481 ttcatttcga tatcgaaata aattggaggt gttatgaaag atggtcattt gctagcccat
    39541 catattcgtt tgttgaatgg gcggattttt caaaagttac tgagtcaaga tcctgaggct
    39601 ctttataggg gtgaacaggg caagatttta gcggttttat ggaatagtga aactggctgc
    39661 gcaactgcga cagatatcgc gcttgcgact gggcttgcga ataatacgct gacgactatg
    39721 ataaaaaagc tagaggaaca aaagcttgta attgttagtc cgtgtggaaa agacaagcgt
    39781 aagaagtatt tagttttaac ggagttaggc aagttccaga aagaagtggg gcatcgtgtc
    39841 agtcagaaat tggatactat cttttacaaa ggattttcag aggaagaaat tcaccaattt
    39901 gaaggttttc aagaaagaat tttggcaaat ctgaaagaga aggaaaatga ggtttagaat
    39961 atgtcacaac aagtgaaaaa tgctcacaac ctatacatcc atgccattca agacggacga
    40021 gttgctgagg ctcaagccca gtctgtaggg gatacctata tccaacattc gacaggtgtt
    40081 cctgacggga aagaaggatt tgcagccttc tttgcagatt tctttgagcg tcatccagag
    40141 cgtcagatta agattgtccg caccattgag gatggcaatc tggtctttgt tcatgttcat
    40201 caatatctga atggtggaga agctcaatgg gtgacgacgg atactttccg tgcggatgag
    40261 aatggtcgta ttgttgagca ttgggatgtc attgactact atcgaacacc tgaaaatgac
    40321 caactagatc aaatttttgg agattttgaa atcaaggatt tggacaagaa agcagaaaat
    40381 aaaaagctgg ttcgccgttt cttgacagaa actttccaaa atggggagct agagcagtgg
    40441 agtgattatg tggcagacga tttgattcag cataatcatg agattggaca aggaagtgct
    40501 gcttataaaa actatgtggc tgaatatagt gtcacttttg actttgtttt ccaactctta
    40561 ggacaaggaa actatgtggt tagctatggt cagactcaga ttgatggcgt tgcttatgcc
    40621 cagtacgata tcttccgttt agagaacggg aaaattgtgg agcattggga taataaggaa
    40681 gtcatgccta aggtagaaga cttgactaat cgagggaagt tttaaattga ggacaaagaa
    40741 tgattgaata caaaaatgta gcactgcgct acacagaaaa ggatgtcttg agagatgtca
    40801 acttacagat tgaggatggg gaatttatgg ttttagtagg gccttctggg tcaggtaaga
    40861 cgaccatgct caagatgatt aaccgtcttt tggaaccaac tgatggaaat atttatatgg
    40921 atgggaagcg catcaaagac tatgatgagc gtgaacttcg tctttctact ggttatgttt
    40981 tacaggctat tgctcttttt ccaaatctaa cagttgcgga aaatattgct ctcattcctg
    41041 aaatgaaggg gtggagcaag gaagaaatta cgaagaaaac agaagagctt ttggctaagg
    41101 ttggtttacc agtagccgag tatgggcatc gcttacctag tgaattatct ggtggagaac
    41161 agcaacgggt cggtattgtc cgagctatga ttggtcagcc caagattttc ctcatggatg
    41221 aacccttttc ggccttggat gctatttcga gaaaacagtt gcaggttctg acaaaagaat
    41281 tgcataaaga gtttgggatg acaacgattt ttgtaaccca tgatacggat gaagccttga
    41341 agttggcgga ccgtattgct gtcttgcagg atggagaaat tcgccaggta gcgaatcccg
    41401 agacaatttt aaaagtgcct gcaacagact ttgtagcaga cttgtttgga ggtagtgttc
    41461 atgactaatt taattgcaac ttttcaggat cgttttagtg attggttgac agctctatct
    41521 caacatttgc agttgtcact tttgaccttg ttactagcta ttttgcttgc gattcccttg
    41581 gctgtttttc ttcgctatca tgagaagctg gccgactggg tcttgcagat tgcaggtatt
    41641 ttccagacca tcccgtctct ggccttgttg gggctcttta tccctttgat gggaattggg
    41701 accttgccgg ctttgacagc tctagtgatt tatgcgattt ttccgatttt acaaaatact
    41761 attactgggc tgaagggaat tgatccgagt cttcaagagg ctgggattgc ctttgggatg
    41821 accagatggg agcgtctcaa gaagtttgaa attccacttg ccatgcctgt tatcatgtct
    41881 ggaattcgga cggcagcggt cttgattatc ggtacggcta ccttggcgac cttgattggg
    41941 gcagggggac tgggttcctt tatcctgttg ggaattgacc gtaataatgc cagtttgatt
    42001 ttgattgggg ccctttcttc tgcagtgcta gctattgcct ttaacttcct actaaaagta
    42061 atggaaaaag cgaaattgcg gacgattttc tctggttttg ccttggtggc tttattactg
    42121 ggtctgtctt atagtccagc tcttttggct caaaaagaga aggaaaactt gattattgct
    42181 gggaaaatag gcccagaacc agaaattttg gctaatatgt ataagttgct gattgaagaa
    42241 aataccagca tgactgcgac tgttaaaccg aattttggga cgacaagttt cctttatgaa
    42301 gctctgaaaa aaggtgatat tgacatttat cctgaattta ccggtacggt gactgaaagt
    42361 ttgcttcaac catcacccaa ggtgagtcat gagccagagc aggtttatca agtggcgcgt
    42421 gatggcattg ccaagcagga tcatctagcc tatctcaaac ctatgtctta tcaaaatacc
    42481 tatgctgtag ctgttccgaa aaagattgct caagaatatg gcttgaagac catttcggat
    42541 ttgaaaaaag tggaagggca gctgaaggca ggctttacgc ttgagtttaa cgaccgtgaa
    42601 gatggaaata agggcttgca atcaatgtat ggtctcaatc tcaatgtggc gactatgcag
    42661 ccagctcttc gttatcaggc aattcagtca ggggatattc aaatcacgga tgcctattcg
    42721 actgatgcgg aattggagcg ttatgattta caggtcttgg aagatgacaa gcaactcttc
    42781 ccaccttatc aaggggctcc actcatgaaa gaagctcttc tcaagaaaca cccagagttg
    42841 gaaagagttc ttaatacatt ggctggtaag attacagaaa gccagatgag ccagctcaac
    42901 taccaagtcg gtgttgaagg caagtcagca aagcaagtag ccaaggagtt tctccaagaa
    42961 caaggtttgt tgaagaaatg atgggacaga gactttaaac atactgaact caacttcctt
    43021 aaacgactag ataaaagaat gctcagacaa tttcgtctgg gcttttttga tgtgagaatg
    43081 actgaatgtc acttaaaatg gaaagaaaga gaaaattttc atgattttct aaaattttac
    43141 tgtaaagaca gttgactatt cataaaatag gtgtataata ttttgtgaac tacttaacaa
    43201 ataagaggtt ttagctcatg tcgactaagg ttagaaatct tgtgtatagg cagttcatta
    43261 tctaatagag cgttgcgtcc gaaagtctat ccagacacgg ctctttaaaa acaaaaggag
    43321 aaatgatgca tacttatttg caaaagaaaa ttgaaaatat caaaacaacc ctaggtgaaa
    43381 tgtcaggtgg ttaccgtcgt atggttgcgg ctatggctga tttaggattt tcaggaacta
    43441 tgaaggctat ctgggatgac ctctttgccc atcgtagttt tgcccagtgg atttatttgc
    43501 tggttttagg aagttttcct ctctggctgg agttggttta cgaacatcgt attgttgact
    43561 ggattgggat gatttgtagc ttgacaggga ttatctgtgt aatctttgta tcggaaggtc
    43621 gagcaagtaa ttatcttttt ggcttgatta actctgttat ttaccttatt ttggccctac
    43681 agaaaggctt ttatggtgag gtgctgacga cactttactt cacagtcatg cagccaattg
    43741 gacttctagt ttggatttat caggcacagt ttaagaagga aaagcaggag tttgtcgcgc
    43801 gtaaactgga cggcaagggc tggacaaagt atctttccat tagtgtgctt tggtggttgg
    43861 cctttggctt catttatcag tctattggtg ccaatcgtcc ctatcgtgat tcaatcacag
    43921 atgcaaccaa tggggtaggg caaatcctca tgacagctgt ttaccgtgaa cagtggatat
    43981 tctgggcggc taccaatgtt ttttcaatct atctctggtg gggagaaagc ctgcaaattc
    44041 aagggaaata tctaatttat ctcattaaca gtctagttgg ttggtatcaa tggagcaagg
    44101 cagctaagca gaatactgat ttacttaact aggaaaagat gtttgaaagt gctgttttga
    44161 gatttcgatt aaaacagata tagttgataa tcaaggattt atagtatgaa aaagaggatc
    44221 ggcgggtcct cttttgttgt tgaaaagata aaaaactcag taacctagaa ataagacaac
    44281 tgagctttac tctatattca atttttagga atgagaaggt ctagataaaa ttggacaact
    44341 tcctggcctg tgaaatcttg accttttttg agccaccagg tcaatgtctc gataaagttg
    44401 gacacgacca agtgttggag gtaagaagta ggcatattag ggtgggcttc ttttaaatta
    44461 tcagctagca cggaatagac atggtgttct agctctttat ggagttgacg gaggaagtag
    44521 tcatttttgg aaaatagcag actggtgata tggtcttggt ttttatgaaa atggagaaag
    44581 aggtgggcga ggtagtcctc ggttgaaatg gcttgctctc tttcaaaaag atgatggaag
    44641 aggtagcggc agagctggtc cagaagaagc tccttacttt catagtgaca gtaaaaggtg
    44701 gatcttccca catctgcgag atcaatgata tcctgaacag tagtggcctc gtagccctta
    44761 gcattcaaaa gttgtataaa agcttgatag atggcttttt tggttttgct gatacggcgg
    44821 tcaatgttag tcatatggac acttaaggca aattgttcag aactgaataa agctgacgtt
    44881 ttgcttctat cctttctttg agttttagtg gataatgata atgaacaagg tgttcataaa
    44941 tctattataa caaaggaatg agaaatatga aggcaaaata tgctgtttgg gtggcttttt
    45001 tcttaaattt gacttatgcc attgttgagt ttattgcagg tggagtattt ggttctagcg
    45061 ctgttcttgc tgactctgtg catgacttgg gagatgcgat tgcaattgga atatcagctt
    45121 ttctagaaac aatctccaat cgtgaagaag acaatcagta caccttgggc tataagcggt
    45181 ttagcctgct aggagccttg gtaacagctg tgattctcgt aacgggctct gttctagtca
    45241 ttttggaaaa tgtcacgaag attttgcatc cgcaaccagt caatgatgag gggattctct
    45301 ggttaggaat tattgcgatt actatcaatc tgttagcgag tctggtggtt ggtaagggaa
    45361 agacaaagaa tgagtctatt ctgagtttgc attttctgga agatacgcta gggtgggtag
    45421 ctgttatcct gatggcgatt gttcttcgat ttacggactg gtatatccta gatcctcttt
    45481 tgtcccttgt catttctttc tttattcttt caaaagccct tccacgtttt tggtctacac
    45541 tcaagatttt cttggatgct gtgccagaag gtcttgatat caagcaagta aagagtggcc
    45601 tggagcgatt ggacaatgtg gccagcctta atcagcttaa tctctggact atggatgctt
    45661 tggaaaaaaa tgccattgta catgtttgtc taaaagaaat ggaacatatg gaaacttgta
    45721 aagagtctat tcgaattttc ctaaaagatt gtggttttca aaatattacc attgaaattg
    45781 atgctgacct agaaactcac caaacccata agcgaaaggt gtgtgacttg gaacggagtt
    45841 atgagcatca acattagaaa aaagtgaaaa atacttgggt actatcttat ttggaataga
    45901 gtaatttctt tattatttaa atatttcaaa aattggtaag agaagagcat tgtataaact
    45961 ccagatatat gattgttaat gataaaaatt tttcgattag atacaaaatg cttgacttgg
    46021 agtcaactca aagttatata ataagataag tgagttagaa tagcgtgaat tcagtgaatg
    46081 aaatgagagg aggttagcgt gtgaatatta aatctgccag tgatttgttg ggaatttcag
    46141 cggatacgat tcggtattat gaacgggttg gtcttgtgcc accgattact cgtactgcta
    46201 ctgggattcg tgattttcaa gatcaggata tcgaagcgct ggaatttatt aagtgttttc
    46261 gttcggcggg tgtctctgta gatagtttag ttgactatat gtcgctctac caaaagggag
    46321 atgaaacgag agaggagagg cttggtattt tagaagagga aaagcaaaaa ttagaggagc
    46381 gcttgtctca gctacagaca gctttaaatc gtttaaatct caaaattaaa ctttataagg
    46441 aaggaaaatt ttaaatgaaa tcagcagtat atacaaaggc aggtcaggtt ggacttgcta
    46501 gcattgaacg tccgcaaata atagaagcgg atgatgtgat tattcgtgtg gttcgtgcgt
    46561 gcgtttgtgg ttcagattta tggaggtacc gtaatccaga aacgaaagct ggacataaaa
    46621 atagtggaca cgaagcgatt gggattgttg aagaagctgg ggaagccatt acgacggtga
    46681 aaccaggtga ttttgtgatt gtccctttta cacatggatg tggtgagtgt gatgcctgtc
    46741 ttgctggatt tgacggttct tgcgacaatc atattggtaa taatttgggg ggtgattttc
    46801 aggcagaata tattcgcttc cactatgcaa actgggcgct ggttaaaatc cctggtcaac
    46861 cttctgatta tacagaaggg atgctcaagt cccttttgac tcttgcagat gtcatgccga
    46921 caggctatca tgcagcgcgt gttgcaaatg ttcaaaaagg ggacaaggtt gttgttatcg
    46981 gtgatggggc tgttggtcaa tgtgctgtca tcgcggctaa gatgcgtgga gcatcacaaa
    47041 ttatccttat gagccgtcat gaagaccgtc aaaagatggc tatggagtca ggtgcgacag
    47101 ctgttgttgc agaacgtggt caagaaggaa ttaccaaggt gcgtgaaatc ctcggcggag
    47161 gagcagacgc agcacttgaa tgtgttggta cggaggctgc tatagaacag gcgctaggtg
    47221 ttcttcataa tggagggcgt atgggctttg taggagtccc acactataat aatcgtgctc
    47281 ttggttcgac atttatgcaa aatatctctg tagcaggtgg ggcagcttct gctacaacat
    47341 acgataagca atttttacta aaagccgtcc ttgatggtga tatcaatcca ggtcgcgtct
    47401 ttacttcaag ttataaactg gaagatatcg accaagccta taaagatatg gatgaacgta
    47461 agacaattaa gtctatgatt gtaatcgaat aaaaaacgaa taggagtttt agaactctat
    47521 tcgtttttta tgttatccta ttcttgattt agggtacttt ctcttaatgt cagtctggtt
    47581 cccagcatgg tcaggctagg aattttgcga ccgtggagga cttccttgtt aagaatatcc
    47641 atacctgctc gccccatttc ttcagtataa actgtaatac tagagagggg aggatagacc
    47701 tgtttggtca gactggtgtc gttgaatgaa atgaggctga cgcgatctgg caggctgatt
    47761 ccagcttctt ggagggcacg gagggcaccg atagctaaac tatcgctggc tgcgaaaaat
    47821 gctggcggaa gttggtctcc caagctctga atggcctcct tcattaagtc atagccagac
    47881 tgggcagtaa atcttccttg aaagaccagt tcatcatgat agattcccct cgcttgactg
    47941 tagtttttga agttttctag acgcttgtcc tgaatgattt cttcttggtc tgttgtttcc
    48001 tcaagccctg ttagaatccc gatgcggtcc atcccttgac tgaggaaata atcgacaacc
    48061 tgtttcatag cagtgtaaaa atccgtgata atacaggtat gtcccaggga aagtgtatcg
    48121 ctgtctagaa atacaagagg cttttggtat tcttcaaagg cagaaatctg agctcggcta
    48181 aattttccga tgcagagaat cccaatcact tcctcgctta gggtaaaagg atggtcatta
    48241 aaatagcgca agatatcgta gtccaactct tgggctcttt tttctattcc taggcgaatc
    48301 tggtagtagt agaggtcgtc tagctcccct tgttcgctga cccattgaat aatggcaatc
    48361 ttttgcttgg gtttatggga ctcgcctgtc ttgaggtgct tggtgtagcc cagctcttca
    48421 gcaacggtta aaatacggtg tctggtttct tctgtaacag ataggctctg gtcgcggttg
    48481 aggacacggg atacggtcgc gatagagaca gaggctagct gtgcaatgtc ttttaaggta
    48541 gccataaatc ctccttgatt aggttagtat atcatatttt tcttcttttt actgatgttt
    48601 tactaaaatt ttagtaaaaa ggattgacct tgggaaattc cttggataca atagaagaaa
    48661 acgattacac gttaagatgg cttaacggac agtcaaagga gaattcatat ggcacaacat
    48721 cttactactg aagtccttcg caaagacttt cttgctgttt ttggtcaaga agcagaccaa
    48781 accttctttt caccaggtcg tattaatttg attggtgaac acacagacta caacggtggg
    48841 cacgtttttc ctgctgctat ttccttggga acttacggtg cagctcgtaa gcgtgacgac
    48901 caagtcttgc gtttctactc agctaacttt gaggacaagg gcattatcga agtgcctctc
    48961 gctgacctca agtttgaaaa agagcacaac tggaccaatt atccaaaagg ggttcttcat
    49021 ttcttgcaag aagctgggca cgtgattgac aaaggttttg atttttatgt ttatgggaat
    49081 atcccaaatg gtgctggctt gtcttcttca gcatccttgg agctcttgac aggagtcgtg
    49141 gcagagcatc tctttgattt aaaattagag cgtctcgatt tggttaaaat cggcaaacaa
    49201 acagaaaaca actttatcgg agtcaactct ggtatcatgg accagtttgc tattggtatg
    49261 ggggctgatc aacgtgctat ttaccttgat accaacacct tagagtatga tttggtgcca
    49321 cttgatttga aggacaatgt cgttgttatc atgaacacca acaaacgccg tgaattggcg
    49381 gactctaaat acaatgaacg tcgtgctgag tgtgaaaaag cagtggaaga attgcaagtt
    49441 gccttggata ttcagaccct gggtgaattg gacgagtggg ccgttgacca atatagctat
    49501 ctaattaaag atgaaaatcg tttgaaacgt gctcgccatg ctgtgcttga aaaccaacgt
    49561 acccttaaag ctcaagcagc ccttcaagca ggtgatttgg aaacatttgg tcgtttgatg
    49621 aatgcgtcac acgtttctct ggagcatgat tatgaagtaa ctggtttgga attagatacc
    49681 cttgttcaca cagcttgggc acaagaagga gttctcggtg ctcgtatgac aggggctggt
    49741 tttggtggct gtgccattgc cttggttcaa aaagatactg ttgaggcctt taaggaagct
    49801 gtaggcaaac actacgagga agtagttgga tacgctccaa gcttctatat cgctgaagtt
    49861 gcaggtggca ctcgcgtcct tgactagtca aaaggaggct ctatagtgac cttagtagat
    49921 aaatttgtaa cacatgtcat ttctgaaagt tcatttgagg aaatggatcg aatctacctg
    49981 accaatcgtg ttttggcacg agtgggagaa ggtgttttgg aagttgagac caatctggat
    50041 aaattgattg acctcaaggc ccagctagtt gaggaagccg ttcgattaga gacgattgag
    50101 gatagtcaga ctgcgcgtga aatccttggt actgaactga tggacttggt gactccttgt
    50161 ccgagtcagg tcaatcgtga cttctgggaa gcctatgcct actctcctga gcaagcgata
    50221 gaggattttt atcaactcag tcagaaaaat gactacatca aactcaaggc cattgctaaa
    50281 aatatcgctt atcgtgttcc atctgattat ggagaacttg aaattaccat caatctctct
    50341 aagcctgaaa aggatccgaa agagattgcg gtagccaagt tggtgcaagc tagtaattat
    50401 cctcagtgtc aactttgttt agagaatgag ggttaccatg gtcgggtcaa ccacccagct
    50461 cgcagcaacc accggattat ccgttttgaa atggttggtc aggaatgggg gttccagtat
    50521 tcgccctatg cttactttaa tgagcattgt atctttttag atggccagca tcgtcccatg
    50581 gccattagtc gtcagagttt tgaacgtctg ttggctatcg tagagcagtt tccaggatat
    50641 tttgctggat ctaatgccga cctgccgatt gtggggggct ctattctaac tcacgatcat
    50701 tatcagggag gccgtcacgt atttcctatg gaattggctc ccttgcaaaa gaccttccga
    50761 tttgctggtt ttgagcaggt caaggctgga attatcaagt ggccaatgtc tgtcctacgc
    50821 ttgacttcgg attccaaaga ggatttgatt aacttagctg ataagatttt ccaggaatgg
    50881 cgtcagtatt cagattctag tgtgcagatt ttagcagaga cagacgggac gccgcatcac
    50941 accatcacac caatagcgcg taagcgtgat ggacagtttg agttggactt ggtcttgcga
    51001 gacaatcaga cttcagcaga gcatcctgat ggcatctatc atccccacaa ggatgtccaa
    51061 catatcaaga aggaaaatat cggcttgatt gaggtcatgg gcttggcaat cttgccacca
    51121 cgtctgaaag aagaagtgga gcaagtcgct agctatcttg taggagaagc tgttacagtt
    51181 gccgattatc atcaggagtg ggcagaccaa ctcaaatccc aacatccaga cctaacggat
    51241 aaagaaaaag cccttgcaat cgtcaaggac tctgtgggtg ctatctttgt gcgtgtactt
    51301 gaggatgcag gagtctacaa gcagacagaa caagggcaga cagcctttat gcgctttgtg
    51361 gaacaggtcg gaatttcact agactaggag ctttctcctt gcacagtcct ataaaaagta
    51421 gtatcatagt gtcgtttgaa atatcaggag gaaacgatga aagactttca ttttgacgct
    51481 atatctgcct ttgaaaatta cgaaattgaa aaaatgagag atggtcacgt tgtggtgacg
    51541 accaaagtag tgaactcgtc gctcaactac tatggcaatg cccatggtgg ctatctattc
    51601 acgctatgtg accaaatcag tggtttggtg gttatctcgc tgggacttga tggggtgaca
    51661 ctccaatcct ctatcaacta ccttaaggca ggaaaactcg acgatgtatt gaccattaaa
    51721 ggagaatgtg tccatcaagg tcgtacaacc tgtgtgatgg atgtggatat caccaatcaa
    51781 gagggcagaa atgtctgtaa agcaaccttt accatgtttg tcacaggcca aaggtctgag
    51841 gaaagacggg taaggatata aagaaaggtg agtgggataa atttatctca ctcattttta
    51901 atttatgaga tatgttagaa ggaaatataa aagagagtgg tgaaatacaa atgtaatagg
    51961 tacatatatg tggtatacta gttatagtag attttaattg cttatatcga gtgagttctc
    52021 atattagtga ggaattttta aatggaatta cactttaatt tagaattagt agaaacctat
    52081 aaaagtaata gccaaaaggc acgtatctta acggaggatt gggtttatcg tcagtcttat
    52141 tgccctaatt gtgggaacaa tcccttaaat cattttgaaa ataatcggcc tgtagcagat
    52201 ttttactgta atcattgtag tgaggagttt gaactaaaga gcaaaaaagg aaatttttca
    52261 tcaacaatca atgatggtgc ttatgcaacg atgatgaagc gtgtgcaggc agataataat
    52321 cctaatttct tttttttaac ttacacaaaa aattttgagg taaataactt tcttgtcctt
    52381 ccgaagcaat ttgttacacc gaaatcaatt attcaaagaa aaccacttgc accaactgct
    52441 agacgagcag gttggattgg ttgtaacatt gatttatcac aagtaccttc taaaggaagg
    52501 atatttcttg tgcaagatgg acaagttaga gatccagaaa aagttacaaa agaatttaag
    52561 caaggtttat ttttaaggaa gagctctctg tcatcaagag gttggacaat agaaattcta
    52621 aattgtatag ataagataga gggttcagaa tttacccttg aagatatgta tcgttttgaa
    52681 agtgacctaa aaaatatctt tgttaagaac aatcatatca aagaaaagat taggcaacag
    52741 cttcaaatat taagagacaa agaaataata gaatttaaag gtagaggaaa gtatcggaaa
    52801 ttatgaaaac gaaacaactt gttgcatcag aagaggtgta tgatttctta aaagtcatct
    52861 ggcctgatta tgaaactgaa agccgttacg ataacctaag tttaatcgtc tgtaccttat
    52921 cagatcccga ttgtgtgaga tggttatctg aaaatatgaa atttggtgac gaaaaacaac
    52981 tagctttgat gaaggaaaaa tatgggtggg aagtaggaga taaattgcca gagtggctac
    53041 atagctccta tcatagatta ttgttaatag gtgaattatt ggaaagcaat ctaaaactga
    53101 aaaagtatac agtagaaatt acagaaactt tatcacgttt agtaagtata gaggctgaaa
    53161 atccagatga agccgaacga cttgtaagag aaaagtataa gagttgtgaa attgttcttg
    53221 atgcagatga ttttcaggac tatgacacta gcatatatga ataggtagat gtttttattt
    53281 tgtcacacaa aaaagaggct cgcacctctt tttcttattt ctttttatga tttaatacgg
    53341 cattgaggac aatagcgagt aggctggcta cgaagattcc gtttgagaag aacatttgga
    53401 aggctgtcgg catgctgaca aagagattac tgttgttgag accgacacct gcagcgattg
    53461 aaacagctgc gataaggaag ttgtgttcat tgttagcaaa gtcaactcgg gctaggattt
    53521 gcatcccttg aatagataca aaaccaaaca tcaccagcat ggcaccgccg aggacggagc
    53581 ttggaatgat ttgggcaagg gcaccaaact taggaagcag tccaaggaga accaggaaac
    53641 cagctgcgta gtagattggc aggcgttttt tgatgcctga caatttaacc aaaccaacgt
    53701 tttgtgaaaa tccggtgtaa gggaaggtgt taaagattcc tccgagaagt acggccaaac
    53761 cttctgcgcg gtaaccgttg cgaaggcgcg tgctgtcgat tggatctttt gtgatatcag
    53821 acaaggctag ataaacacca gttgactcaa ccatagacac cgttgcgatg atacacatca
    53881 tgacaataga tgagatttca aaggttggca tcccaaagta gagtggagtt gggacatgga
    53941 caagtggagc taccgcaaca ggagagaagt ccaccaagcc catagtagca gcaatggcag
    54001 ttccaacaac cagaccaatc aaaatagaga tagacttgat aaatcctttg gtaaagatgt
    54061 tgatcaagag gataatcaga acagtaatag ctgaaagcaa gagactttga ccagttggct
    54121 ctggaacgtt atttcccata tttccaatag cgacagggat caaggttaaa ccaatcgtgg
    54181 taataacaga tcctgttacg atagatggga aaagattggc tacttttgag aagatgcctg
    54241 aaacaagaac cacgtaaatc ccagatgcga taagggcacc aaacatagcg ccactaccat
    54301 ggctttgccc aatcataatc aagggagcga ccgactggaa tgcaactcca agaacgactg
    54361 ggagtccaat cccaaagtat ttgttgagtt ggagttggag gaaggttgcc accccacaca
    54421 tgaagatatc tgtagaaatc aggtaggtca actgctcagc tgaatagcca agggctgtcg
    54481 caatcatgat gggaaccagg atagatcctg agtacatggc tagtaagtgc tgcaagccca
    54541 gaacggctgc ttgcgagtgt ttttcttgag tttgcattag agatctgcct ccttaaataa
    54601 gacctgacca ttttcaaaac gatccaagcg agcaagtgat aggacagggt agcctgcttt
    54661 ttcaagcaaa tcacgaccat cttggaagga tttctcaatc acgataccga tagcttggac
    54721 tgtggcaccg gcctgttcga tgatttgaat caagccttta gcagcttggc cattagcaag
    54781 gaaatcgtcg ataatcaaaa ccttgtcctc tggtgagagg aattttccag cgatagaaac
    54841 agtgctggtc acctgcttgg taaaggagta gacttgagca gttaagatgc cttcgttcat
    54901 ggtgatgttc ttagcttttt tggcgaaaat catgggaacg tttaaggctt cagctgtaaa
    54961 aacggctggg gcaatacccg acgcttcaat ggttacgacc ttggtaatgc cggcagcagc
    55021 aaatttttcc gcaaaaacct taccaatctc tcgcatcaag ctaaagtcaa cttggtgggt
    55081 taaaaaggaa tctaccttga ggatgttatc atccaagata tgcccatcct tgaggatgcg
    55141 ctcttctaat aatttcataa gacctcctaa agtctaaaag ttaatttact tgttgtttaa
    55201 atatttctat agtgatccct tttgctaata ctatatattt gataaaacta ttacgagcga
    55261 agcgagtctt atcaaatatt tcccgttgta gtggtatcat agacaataat cttgttattg
    55321 tctatgacgg gatttttgag agtaaaatag ttcggggaac tattttagcc taagcctaga
    55381 aatgaaagag ctaggggctc aaaaattagg gatgaaattc cctggattcc tgaaattatt
    55441 cacaggataa tttcacctcc cgtccgcact aattaaggga aatattaaaa atattcaaaa
    55501 aagacctact taatctctaa gtaagtcccc taaatagaca tggcaaaaac ggccatatct
    55561 cactgctgac ttacttattg ttaggtgttc cggcaccttg tagaaacgtc gtgccaattc
    55621 acgacataaa caagtaaaac gatattcaat tttaaatagg cttgagccaa tgtttttatt
    55681 ttacactaaa taactttata aatcaactat tttgttagtg tttcggttta aaaagcgaac
    55741 aaaaagaaga gagggtgaac aaaaactcca ttgtaagcta acatttatac taaatgaaaa
    55801 tcaaagagca aactaggaag ctatccacaa cctcaaaaca ctgttttgag gttgtggata
    55861 gaattgacag agtcagtatc atatacctac ggtaaggcga cgttgacgtg gcttgaagag
    55921 attttcgaag agtattagaa gatttttcca tcataaaagg catactatca agtttttaga
    55981 cacctgacaa tatgcctttt tctaacttta aagacttttc ccaattttta ttattctact
    56041 cgctaaatct taaaaaatag ccatctggat ccaaaactgc aaatttatga ggatagatat
    56101 agggatcact gacacgaaac tttcttttgg tcaagagacg ataaatagga tagtttgcct
    56161 ccatcacttt ttgatagagt tttggaacat cctttatgcc aaaggagaga ttgactccac
    56221 gaccaaaggg gtaggtcagt tcagctagtt gatcctttgt tccctcctct aacattagtt
    56281 gacactcttc aagagaaaga gaaagttttc ttctggacgt tagtattcaa tcctaaaacc
    56341 cagtaaacca cagtagaagg accgggactg ttcgatattc gatacaagaa actcgggaat
    56401 gaccgcattg tagtccatat agaaaatcct tacaagtcaa tttccaagac aatcggtgta
    56461 tggtcttggc gagcacctga gtcaatcata tcagatttag tgaccttgtc agcgatacgg
    56521 ttacttgtga gccagtagtc gattctccag cctgtattgt tgattttaga agttttgctg
    56581 cgttgtgccc accaagtgta gcgttcagga acatcgccat gaacatggcg gaaggtgtct
    56641 gtaaatccag ttgccaaaag gttggtaaat ccagcacgtt cctcgtcagt aaatccaggt
    56701 gaacggcggt tgctagcagg atttgcaagg tcgatttcat tgtgggctac gttgtagtca
    56761 ccggtcgcaa ggactggttt ttctttgtct agttcagcca aatactccgc atatttgaca
    56821 tcccagactt ggcgttcttc caagcgtttg agaccgtcac cagcgtttgg agtgtaaact
    56881 tgggttacga aaaatgcatc aaattctaga gtgatgatac ggccttccaa gtccatggta
    56941 gaaggggcac cgatttctgg aaaactgatc gtaggcgtaa gttctttctt ataaaggaac
    57001 atggttccag catagccttt acgggcaggc tcttgggaag agcgccatgt gttttcgtag
    57061 cctgggaaga gttcttctaa aatttccacg tgtttctttg taggtccttt ggcagaaagc
    57121 ttggtttctt ggatagcaat gatatcagca ttttcagcga ccaaggtttg taggacttct
    57181 tgggacaatt tggcacgagc tgagtcacta gttagggcag cgtttaggga atcaatattc
    57241 catgagataa gtttcataaa gttacctttt tcattcagat tatagatttt attataccaa
    57301 aaaaagatct atttccccaa cgtatggttt gaaaaattac tctctttcgt ttataattaa
    57361 gaatgatttt atgaaaggga gtgaaaatac atgaaattct actcttatga ctatgtactc
    57421 agccaaatcg gtcagcaaaa tggtatcatg gttggctttg ggattgtttt attagctgtg
    57481 acagtttttt ttgctttcaa ggcataccat gataaaaaag gaaccaaatt tcgtgagttg
    57541 gtcataattt cagctctggc cttatttagc tatgcttttg gtcagcatca cgacttatca
    57601 aaacaatcaa gtttctaaca ataaatttca aacttcactt catttcatcg aggttgtttc
    57661 caaagatttg ggagtagaca agtcagaagt ctatgttaat acttccacaa acacagatgg
    57721 cgcacttatc aaggtgggag atcgctatta tcgtgcccta aacggaagtg agccagacaa
    57781 gtacctgtta gagaaagtcg aattgtataa gacagacgca attgaactgg tggatgtgaa
    57841 caaatgacac ttaattatat cgaaatttta atcaaactga tcttgactct caaatagctc
    57901 aacaacaatg ttcactttgt gaaacgtttg attgatggta agccaactct ccttatcaaa
    57961 aatgggaata ttgacccaga agcctgtcgt tcagttggtt tgtctgcatc ggatgtatcc
    58021 ctcaaacttc gtagccaagg gattttccag atgaagcaag tcaaacgagc tgtgcaagag
    58081 caaaatgggc aactcatcgt tgtgcaaatg ggagatgaaa atcctaagta tccagttgtg
    58141 actgacggtg tgattcaagt agatgtcttg gaatcgattg gtcgtagcga agagtggttg
    58201 cttgataacc tcagtaaaca agggcatgac aatgtagcca atatctttat tgctgaatat
    58261 gacaagggtg ctgttacagt cgtaacttat gaataagaaa aacctggggt cttgtactct
    58321 tcgaaaatct cttcaaaccg cgtcaacgtc gccttgccgt atgtaggtta ctgacttcgt
    58381 cagttctatc tacaacctca aagcagtgct ttgagcagcc tgcggctagt ttcctagttt
    58441 gctctttgat tttcattgag tattggcctc aggtttccat ttgcaatcag aaagggattt
    58501 tatgtccatt attcaaaaac tttggtggtt tttcaagtta gaaaaacgcc gttatctagt
    58561 cggaattgtg gccctgatct tggtttccgt cctcaatctc attcctccta tggttatggg
    58621 gcgggtcatt gatgccatca catcggggca attaacccag caggacctcc ttcttagcct
    58681 attttacttg ctacttgcag cctttggtat gtactatttg cgctatgtgt ggcgtatgta
    58741 tatccttggg acctcttatt gcttgggaca gatcatgcgg tctcgcttgt ttaagcattt
    58801 cacaaaaatg tcgtcagcct tttatcaaac ctatcggacg ggtgatctga tggcacacgc
    58861 aaccaatgat atcaatgcct tgactcgttt agcaggtggc ggtgtcatgt ctgcggtgga
    58921 tgcctctatc acggctctgg tgactttgtt gaccatgctc tttagcatct catggcagat
    58981 gactcttgtt gccattctcc ccctaccttt catggcctat gcgactagtc gcctagggag
    59041 aaagactcat aaggcctttg gcgaatccca agctgctttt tctgaactca ataacaaggt
    59101 acaggagtcc gtatcaggta tcaaagtgac caagtctttc ggttatcagg cagacgagtt
    59161 gaagtctttt caggcagtca atgaattaac cttccaaaag aacctgcaaa ccatgaaata
    59221 tgatagtctc tttgacccta tggttctctt gtttgttggt tcgtcctatg ttttaacgct
    59281 tttggttggc tccttgatgg ttcaggaagg gcagattaca gttgggaatc tggtcacctt
    59341 tatcagctat ttggatatgc tggtctggcc tcttatggcc atcggcttcc tctttaatac
    59401 tactcagcga gggaaggttt cttaccagcg gattgaaaat cttttgtctc aggaatctcc
    59461 tgtacaagac cctgagtttc ctctggatgg tattgaaaat gggcgtttgg agtatgccat
    59521 tgacagcttt gcttttgaaa atgaggaaac actgacggat attcacttta gtttggcaaa
    59581 agggcaaaca ctgggcttgg ttgggcagac aggctctggg aaaacgtcct taatcaagct
    59641 tctcttgcgt gaatacgatg tggataaggg cgccatttat ctaaacggtc acgatattcg
    59701 ggactatcgt ctgacagacc ttcgcagtct catgggctat gttcctcagg accagtttct
    59761 ctttgcaact tcaatcctag acaatatccg ctttggcaat cctaacttgc ccctttcagc
    59821 ggtcgaggaa gctactaagc tagcccgagt ttaccaagat attgtagaca tgcctcaagg
    59881 atttgatacg ctgattggtg aaaaaggagt cagtctttct ggtggtcaaa agcaacggtt
    59941 ggctatgagt cgggctatga ttttaaaccc tgatatcttg attttggatg attccttatc
    60001 cgccgtagat gccaagacag agtatgcgat tatcgacaac ctcaaggaga cgcgaaagga
    60061 caagacaacc attatcactg cccatcgcct cagtgctgtt gtccatgcag attttatttt
    60121 agttctacaa aatggtcaaa ttatcgaacg aggcaggcac gaagacttgc tagcgatgga
    60181 tggctggtat gcccaaacct accagtctca gcagttagaa atgaaaggag aagaagatgc
    60241 agaataaaca agaacaatgg gctgtattga agcgcttgat gtcttatctc aagtcttatg
    60301 gactcctgat ctttttggca ctcagttttc tcctagcgac gacggtcatt aaaagtgtca
    60361 tacccctcgt ggcttcccac tttatcgacc agtatctcag caatcttaac caactagccg
    60421 ttaccgtttt gctggtctac tatggtctct acatcctaca aactgtagtt cagtatgtag
    60481 gcaatcttct ctttgcgcgc gtgtcttaca gtattgttag ggatattcgt cgggatgcct
    60541 ttgccaatat ggagaaactg ggcatgtctt actttgacaa gacgccagca ggttctatcg
    60601 tttctcgttt gaccaacgat accgagacga ttagtgatat gttttctggg attttatcca
    60661 gctttatctc agcagttttt atctttctga caacccttta taccatgttg gtgctggatt
    60721 ttcgtttgac ggctttagtc ttgctctttc ttcctttgat tttccttttg gtcaatctct
    60781 atcgaaaaaa gtcagtgaaa atcatcgaga aaaccagaag tctcttgtca gatatcaata
    60841 gtaagctggc agagaatatc gagggaatca ggattattca ggcttttaat caagagaagc
    60901 gcctgcaggc agaatttgat gaaatcaacc aagaacactt ggtctacgcc aaccgttctg
    60961 tagccttgga tgccctcttt ttgagacctg ccatgagttt gctgaaactt ctaggctatg
    61021 cagtcttgat ggcctacttt ggctaccgtg gtttttctat cgggataacg gtcgggacca
    61081 tgtatgcctt tatccagtac atcaaccgcc tttttgaccc cttgattgag gtgacgcaaa
    61141 acttttcaac tctgcaaacg gctatggttt ctgcaggtcg tgtctttgcc ctgatagacg
    61201 agaggaccta tgaacctctt caagaaaatg ggcaagccaa agtccaagaa ggcaatatcc
    61261 gttttgaaca tgtgtgtttc tcatatgacg gtaaacatcc gattctggat gacatttctt
    61321 tctctgttaa taagggtgaa accattgcct ttgtaggtca tacaggttca gggaaatcgt
    61381 ctattatcaa tgtcctcatg cgcttttatg aattccagtc agggagagtt ctcttggatg
    61441 atgtggatat cagggatttc agtcaagaag agctgagaaa aaacatcggt ttggtcttgc
    61501 aggaaccctt cctctatcat ggaactatta agtccaatat tgccatgtac caagaaatca
    61561 gtgatgagca ggttcaggct gcggcagcct ttgtggatgc agattccttt attcaagaac
    61621 ttcctcaggg gtacgactcc cctgtttccg agcgtggttc gagcttctct actgggcagc
    61681 gccagcttct tgcctttgct agaacagtcg ccagccagcc taaagtcctg attttggatg
    61741 aagcgacagc caatattgac tctgaaacag aaagcttggt tcaagcttct ctggcgaaga
    61801 tgagacaggg ccgaacaact attgctatcg ctcaccgcct ttctactatt caagacgcca
    61861 actgcatcta tgtcttggat aagggacgca ttatcgagag tggaacccat gaggaactct
    61921 tggctctggg aggaacttat cacaagatgt atagtttgca ggcaggggcc atggccgata
    61981 ctctttgaaa atctctttaa accatgtcag ctttatctgc aatctcaaag ctgtactttg
    62041 attttcattg agtactagaa ggaaatcctt caaattacag atttctttca ccgccttttc
    62101 cattttgtgg tataatgaaa aatgttgaca aatagtataa taaaaacaaa ggagaacagc
    62161 atgctgaaat gggaagactt gcctgtggaa atgaaatcaa gcgaggttga gtcttactac
    62221 cagcttgtct ctaaaaggaa gggttcgctg attttcaagc gttgcttgga ctgggttttg
    62281 gccttggtct tactggttct aacttctccc atctttctca tcttgagcat ttggatcaag
    62341 ttggatagca aggggccagt gatttacaag caagagcgtg tgacccagta caactgtcgg
    62401 ttcaagattt ggaagttccg taccatggtg acggatgcgg ataaaaaagg aagtctggtg
    62461 acttctgcta acgatagccg tattaccaag gttggaaatt tcatccgacg tgtccgtttg
    62521 gacgaactgc ctcagttggt caatgtcctt aaaggtgaga tgtcctttgt cggtacacga
    62581 cctgaagtgc cacgttatac agagcagtat agccctgaaa tgatggcaac cttgctcttg
    62641 caagcaggaa ttacctctcc agccagcatc aactacaagg atgaggacac catcatcagt
    62701 caaatgacgg agaaaggtct gtcagttgat caggcctatg tggagcatgt tcttcctgaa
    62761 aagatgcgct ataacctcgc ctatctccga gagtttagtt tctttgggga catcaaaatc
    62821 atgtttcaaa ccgtgtttga ggtactaaaa taaagtagtc ataagaaaat gagtacagat
    62881 aaaaggagca aatcaatgcc aaattacaat attccatttt caccgcctga tatcacagaa
    62941 gcagaaattg ctgaagtagc ggataccctg cgttctggtt ggatcacaac aggtcctaaa
    63001 acaaaagaac tggagcgccg cttgtctctt tacacacaga cacctaagac tgtttgtctc
    63061 aactctgcga cagccgctct ggagttgatt ttacgcgttt tggaagtggg acctggtgat
    63121 gaagtcatcg ttccagccat gacctatacg gcttcatgta gtgtcattac gcacgtggga
    63181 gcaacccctg tcatggtgga tatccaagca gatacgtttg agatggacta tgacctgctt
    63241 gagcaagcta tcactgagaa aactaaggtg attatcccag tagagctcgc agggattgtt
    63301 tgcgattatg accgtttgtt ccaagtcgtg gagaaaaaac gtgacttctt taccgcttca
    63361 agcaagtggc aaaaggcctt taaccgtatt gtcattgtct ctgatagtgc ccacgctttg
    63421 ggatctactt ataaaggaca accttctggt tctatcgctg actttacttc cttctcattc
    63481 catgccgtta agaactttac aacggcagaa ggtggaagtg cgacttggaa agccaatcca
    63541 gtgattgatg acgaagagat gtacaaggaa ttccaaatcc tttcccttca cgggcaaact
    63601 aaggatgctc ttgccaagat gcaattgggg tcatgggaat acgatatcgt tacaccagcc
    63661 tataagtgca acatgaccga tatcatggct tcacttggtt tggtacaatt ggaccgctat
    63721 ccaagtttgt tgcaacgccg taaggacatt gtggaccgct atgatagtgg ttttgcaggt
    63781 tctcgcatcc atcctttggc acacaagact gaaactgtcg aatcttcacg ccacctctac
    63841 atcacccgtg tagaaggagc aagcctagaa gaacgcaacc tcatcatcca agaattggct
    63901 aaagcaggaa ttgcaagtaa tgttcactac aaaccgcttc ctctcttgac agcctataag
    63961 aatcttggat ttgatatgac gaactatcct aaggcctatg ccttctttga gaatgaaatt
    64021 accctccctc ttcatactaa attaagcgat gaagaagtag actatatcat tgagactttc
    64081 aaaacagttt ctgaaaaagt gctaacttta tcaaaaaaat gacaaactac agtcaagcga
    64141 aagtgatcct gtccctaaaa agtctaattg agtgtaaaaa ctgttgtttt caattgataa
    64201 tagtttacac ctgtagttga ggcctctttc tcctcagaga gagaattttt ataggatttt
    64261 cctttcttgt gggagtcccg tggtttgaaa taagatgtga gcaatttagt gtagcattta
    64321 gaatccttac tagacatcat ttagaaaatc tagtgtcttg ttctagtttt caattcaccc
    64381 tattttttga aagacgtgag tttccatgag tgagattgtg gaaactcgcg tctttttttg
    64441 ttttcagaat attgttcaaa attttgtgcc tgtctttcat gttctagtca ttcttttgca
    64501 tgatagaatt tatagcatgt tgatattata ataatacaaa tattctatat gtttagtgat
    64561 gcttgctata catcattaga tctcctgcga gacaatctat aaaacacttg tctacgatta
    64621 cctatatgcc ctattccagt attttagaag cactgcatct atttttatcg aggttaaatc
    64681 tagcttttat agaaggtcta tttaagaaat atattgtagt gttttagttt caatccgcca
    64741 tatgagcgat attcaggtaa atatccctgg cgaatgcttg tatgacaagg tatttgttct
    64801 ttcatttata atttacaaca tatcaacaaa tttaaatata gtaaatggga tattttatat
    64861 tcaagctaag aaagatagca tcacttttga atggaaggct aaagagcaaa ctaggaagtt
    64921 ggccatagat agctcaaaac cctgctttga ggttgtagat atagtaaaat gaaataagaa
    64981 taggacaaat tgatcgggac agtcaaatcg atttctaaca atgttttaga agtagaggtg
    65041 tactatttta gtttcagtct actatagaac tgaccaagtc agtaacctag acttagggca
    65101 aggcggcact gacctagttt gaagagattt ccgaagagta taaattttaa tattttcttg
    65161 tgttattcct tgacaattca atttggaaaa tatatgataa agataatgac agcggtgtca
    65221 ttctatctat tttaagaaaa gtaataatca attgttaaaa atagtaaaaa aattggaggt
    65281 tctgatgaaa tattttgttc ctaatgaggt attcagtatt cgtaaattaa aggtggggac
    65341 ttgctcggta ctattggcaa tttcaatttt gggaagccaa ggtattttat cggatgaagt
    65401 tgttactagt tcttcaccga tggctacaaa agagtcttct aatgcaatta ctaatgattt
    65461 agataattca ccaactgtta atcagaatcg ttctgctgaa atgattgcct ctaattcaac
    65521 cactaatggt ttagataatt cgttaagtgt taatagtatc agctctaatg gtactattcg
    65581 ttccaattca caattagaca acagaacagt tgaatctaca gtaacatcta ctaatgaaaa
    65641 taagagttat aaggaagatg ttataagtga cagaattatc aaaaaagaat ttgaagatac
    65701 tgctttaagt gtaaaagatt atggtgcggt aggtgatggg attcatgatg atcgacaagc
    65761 aattcaagat gcaatagatg ctgcagctca agggctaggt ggaggaaatg tatattttcc
    65821 tgaaggaact tatttagtaa aagaaattgt ttttttaaaa agtcatacac acttagaatt
    65881 gaatgagaaa gctacaattc taaatggtat aaatattaag aatcaccctt ccattgtttt
    65941 tatgacaggt ttatttacgg atgatggtgc gcaagtagaa tggggcccaa cagaagatat
    66001 tagttattct ggtggtacga ttgatatgaa cggtgctttg aatgaagaag gaactaaagc
    66061 aaaaaatcta ccacttataa attcttcagg tgcatttgct attgggaatt caaataacgt
    66121 aactataaaa aatgtaacat tcaaggatag ttatcaaggg catgctattc aaattgcagg
    66181 ttcgaaaaat gtattagttg ataattctcg ttttcttggg caagccttac ccaaaacgat
    66241 gaaggatggg caaatcataa gtaaggagag cattcagatt gaaccattaa ctagaaaagg
    66301 ttttccttat gccttgaatg atgatgggaa aaaatctgaa aatgtgacta ttcaaaattc
    66361 ctattttggc aaaagtgata aatctgggga attagtaaca gcaattggca cacactatca
    66421 aacattgtcg acacagaacc cctctaatat taaaatttta aataatcatt ttgataacat
    66481 gatgtatgca ggtgtacgtt ttacaggatt cactgatgta ttaatcaaag gaaatcgctt
    66541 tgataagaaa gttaaaggag agagtgtaca ttatcgagaa agcggagcag ctttagtaaa
    66601 tgcttatagc tataaaaaca ctaaagacct attagattta aataaacagg tggttatcgc
    66661 cgaaaatata tttaatattg ccgatcctaa aacaaaagcg atacgagttg caaaagatag
    66721 tgcagaatat ttaggaaaag tatcagatat tactgtaaca aaaaatgtaa ttaataataa
    66781 ttctaaggaa acagaacaac caaatattga attattacga gttagtgata atttagtagt
    66841 ctcagagaat agtatattcg ggggtaaaga aggaattgtt attgaggatt caaagggtaa
    66901 aataaccgtt ttaaataacc aattttataa tttatccggt aagtatatat cattcatcaa
    66961 atctaatgca aatgggaaag aacctgttat acgtgatagc gatggtaatt tcaatattgt
    67021 aacggagaat gggctttaca atattgtaac aaataattta agtgataaaa acgaaaaaga
    67081 aaaaaacaaa gaggaaaaac aatctaattc aaataatgta attgatagta accagaagaa
    67141 cggagagttt aactcaagta aagataatag acaaatgaat gacaagatcg acaataaaca
    67201 agataataag acagaagaag taaactataa aatagttgga gatggcagag aaactgaaaa
    67261 tcatattaat aaatctaaag aaatagtaga tgtaaaacaa aaattaccaa agactggttc
    67321 gaacaagatt atggaactat tcttaacagt gacaggaatt ggtttacttt tgacactaaa
    67381 agggttgaag tattatggta aagataaata aaatttgttc gatacaagga agttccgtag
    67441 aaaatgagga tattgtaggt tcacaaaatc agtatttttg gattattggt ggagctacag
    67501 atttatataa ttctaaagag gagataggtt attcagtctc agaagttgta catattttat
    67561 cagaaagttt gtcggttaat tgtaaagaat caaaaactct taaacaaata tttgaaactg
    67621 ctttactcga ggttaaagat gaaatcggtt taaactcata tgaattaaca gagtatagta
    67681 aaatgaaata ataataggac aaatcaatca ggacagtcaa atcgatttct aacaatgttt
    67741 tagaagtaga ggtgtactat tctagtttca atatactata ttatcgctta ccaatatttg
    67801 ctaaactttc agaaaaaaag ttggagtata tgatgctagg tgactgcgtc atgttagtaa
    67861 acgaaatgga aataactgat catagagtag ataacttatt tgaaaaaggg aaaaatgaga
    67921 taaaagattc aagtagtaga tttagcaata ggacatataa aagctttaga aaaagtatct
    67981 gaaaaaacag atgtttatat ctataaccta ggctcgggag aaggcactag tgtattacaa
    68041 cttgtaaata catttgaaag tgttaataag atccctattc cttataaaat agttccaaga
    68101 cgttcaggag acgttgcaac ttattatgca aatgcagaca aagcatataa ggaattaaat
    68161 tggaggacaa caaaatcgat tgaagacatg tgtagagata catggaattg gcaatcaaaa
    68221 aatcccaatg gctataattg atgatactgt ctatatgagt gctgtatttt ggaaaaatta
    68281 cttaaccttt taatgaaaga taaattaaaa aaaatgtttg acagcgcttg acaaaggaaa
    68341 cggtttcatt gtataatgta aacacaatga caccgatgtc aaatataaaa aagaaggtct
    68401 ttatatgaaa aacttaacaa aaattaagtt caaagaaaat ggggaattta atcatttccc
    68461 tgggaataca gttgtagcaa atctttatac taaacaagat ttgatggaag ttgttgatat
    68521 tattcaatca cgttatagag aattaccatt tatcgataag tttactttaa ctccaaggaa
    68581 ttctattcac atgactgtaa ttgaattgtt gtgccatgaa aatcgtgaaa cggagttttg
    68641 gagcagtaat cttcctctag atacaccttt acaggaaata catgattact ttgctaaaca
    68701 acttgaaatt tttccattgt tggatgaaga aattcatatg cgtataactg aaatgggaaa
    68761 acaaaacata ctagttgaac ctgcagatga agcttctgca aagagattag aagaaattcg
    68821 tacttatgtc tcagaaaaag caggtgtttg tttccctaat catgatagat atcaattcca
    68881 tatttcaatt gggtatcttc ggattcctct aaccgaagag gaggaagaag agtttactaa
    68941 agtcagagca gaattaactg aaattttatt agagaagatt ccaactatta ctgtaaaccg
    69001 tattgactat actgtatttg aagatatgag acaatttgtt ccatatcacg aaaaatttaa
    69061 ataaaataat aaaaaaggag aacttatcat gaaaaaaatg aaagtttggt ctactgtact
    69121 tgcaacggga gttgctctta ctacacttgc tgcttgctct ggaggttcaa attctacgac
    69181 tgcttcttca tctgaagaaa aagctgataa aagtcaagaa ttagttatct attcgaactc
    69241 agtctcaaat ggtcgtggtg attggttaac tgctaaagca aaagaagctg gttttaatat
    69301 aaaaatggtt gatatcgctg gcgctcaatt agcagaccgt gttattgctg agaagaataa
    69361 tgcagttgca gatatggtat ttggaattgg tgctgttgat tcaaataaaa ttagagatca
    69421 aaaattacta gtacagtaca agcctaaatg gttagataaa attgatcaat ctttatcaga
    69481 taaagataat tattataatc ctgtgattgt tcaaccatta gttttaattg gggcgcctga
    69541 tgtaaaagaa atgcctaaag attggactga attaggtagt aagtataaag gtaaatattc
    69601 aatttatggt cttcaaggtg gtacaggacg ggcaattcta gcaagtatct tagttcgtta
    69661 ccttgatgaa aaaggagatt taggcgtatc agaaaaagga tgggaagttg caaaagaata
    69721 ctttgcaaat gcctatactc ttcaaaaagg tgaaagctca gttgttaaag cgttagataa
    69781 agaaagccca attcaatacg gtatgatctg gggttctgga gcgttaattg gacaaaaaga
    69841 acaaaatgtt gaattcaaag ttatgactcc tgagattggt gtaccatttg taactgaaca
    69901 aactatggtt ttaagcacta gtaaaaaaca agcgttagct aaagaattta ttgattggtt
    69961 tggtcaatca gaaattcaag tagaatatag taaaaaattt ggatctattc ctgccaataa
    70021 agatgcccta aaagagttac ctgaagatac gaaaaaattt gttgatcaag tgaaaccaca
    70081 aaatattgac tgggaagctg ttggaaagca tttggatgaa tgggtagaaa aagctgaatt
    70141 agaatacgta aaataagaaa taagagttat tttttatgtc caagtctctc tattatttct
    70201 aaatttaagg aagaaataaa gagaggcttt tggttttagt aatagaggga gttagtgaga
    70261 tgattaaatt tgataatatt caaattaaat atggtgattt tgttgcaatt gataatctga
    70321 atttagatat acatgaaggg gaattcttta catttcttgg gccttcagga tgtggtaaat
    70381 caactacttt gagagcattg gtaggttttt tagatccatc atcaggaagt attgaagtta
    70441 atggaacaga tgtcactcat ttggaacctg aaaagcgtgg aattggtatt gtatttcaat
    70501 cttatgcgct atttccaact atgactgttt ttgataatat tgcatttggt ttaaaagtta
    70561 agaaggtagc tccagatgtt attaaagcta aagtatcagc agtggcagca aaaattaaga
    70621 tctctgatca acagttacag cgtaatgtat cagaattatc tgggggtcaa caacaaaggg
    70681 tagcattggc tcgtgctctg gttcttgaac ctaaaattct ttgtctagat gaaccattgt
    70741 caaaccttga cgcaaaatta cgtgtagatt tgagaaaaga gttgaaaaga cttcaaaaag
    70801 agttaggtat tactacttta tatgttactc atgatcaaga ggaagccttg actttatctg
    70861 atagaattgc agtctttaac aatggataca tcgaacaggt cggtacacca gtagagattt
    70921 atcataattc tcaaactgaa tttgtatgtg attttattgg agatattaat gttttgaccg
    70981 atgaaacagt ccacgaagta ttattgaaaa atacaagcgt tttcttagag gataaaaaag
    71041 gatacattcg attagagaaa gttcgattca atcgtgaaac tgaacaagat tttattctaa
    71101 aagggacaat tattgatgtt gagttttctg gagttacaat tcactataca ataaaagttt
    71161 ctgaaagtca gattcttaat gtaacaagta ttgatagtca ggctgctatt agatctgtcg
    71221 gagaaagtgt ggaattattt atcataccat cagacgttct gcaattttaa ggaggtgcag
    71281 tatgcgtcat aaattaaatt taaaagattg gcttattcgt ttagggttaa tctggttctt
    71341 agtaacattt attatttatc caaactttga tctagtagtg aatgtatttg taaaaggagg
    71401 agaattttcc cttgatgctg tacatcgtgt tctaaaatct cagagggcac ttcagagtat
    71461 tatgaacagt tttaagttag cattttcact cattattaca gttaatgtcg taggtattct
    71521 ttgtgttcta tttacagagt actttgatat taaaggtgct aaaattttaa aattaggtta
    71581 tatgacctct ttaatttatg gaggagtggt tttagcgact ggatataaat ttgtctatgg
    71641 tccttatgga ttgattacaa aatttttaca aaatgttatc ccttctttag actctaactg
    71701 gtttattggg tatggtgcag tcttattcat tatgacattt tcaggaactg ctaatcatac
    71761 attgttttta acaaatacaa ttcgaagcgt tgactatcac actattgagg ctgctcgaaa
    71821 tatgggagca aaaccattta ctgttttccg aaaagtagtg ttaccaacct taattccaac
    71881 tctatttgca cttactatta tggtttttct tagtggttta tctgcagtag cagcacccat
    71941 gattgttggt ggtaaagaat ttcaaactat aaatccaatg attattacat ttgcagggat
    72001 ggggaattct cgtgatttag ctgccttact tgcaattatt ttaggtattg caactacaat
    72061 tttgcttact atcatgaata agatagaaaa aggtggaaat tatatttcta tctctaagac
    72121 taaagcgcct cttaaaaaac aaaaaattgc gtctaagcct tggaatatca ttgctcacat
    72181 tgtagcatat ggattgttca cagttttcat gcttccacta atttttatag tattatactc
    72241 atttacagat ccagttgcaa ttcaaacagg taacttaaca ttatcaaact ttactttaga
    72301 aaattatcgc ttattcttta gtaatagtgc ggcattctct ccattcttgg tcagctttat
    72361 ttattctatt attgctgcga caacagcaac aattctcgca gttgtatttg ctcgtgttgt
    72421 cagaaaacat aaatctcgtt ttgatttctt atttgaatat ggtgctctac ttccttggtt
    72481 actaccaagt acacttttag cagtaagttt attatttact tttaatcagc cacaatttct
    72541 tgttttgaat cagattttgg taggtagttt ggtaattcta cttattgcat atatagttgt
    72601 aaaaatccca ttttcttata gaatggtacg tgctatttta tttagtgttg atgatgagat
    72661 ggaagatgca gcaagaagta tgggtgcttc acctttttat actatgatga aggttatcat
    72721 tccatttatt ttaccggttg ttctctctgt tattgcttta aactttaact ctttattaac
    72781 tgacttcgac ttatctgtat tcctttacca tcccctagct caaccattag gtattacgat
    72841 tcgatctgca ggtgatgaaa cagcaacatc taatgcacaa gctctggtat ttgtttatac
    72901 aattgttctg atgattattt ctggaacggt attatacttc acacaaagac cggggcgtaa
    72961 agtaaggaaa taatcatgac agccactagt cttgggttat caaatattga aatagttgtc
    73021 aggattgttt tatcagtagt cattggtagt ataattggtt tagagagagg gagcaaatcc
    73081 cagcctgcag gcatccgaac ttatagtatt gtttgtctag ctgcatgttt gattatgatg
    73141 acgaatgaat acgtatctta taaatttggg acaggagatc ctacacgatt aggagctcaa
    73201 gttatatcag gtgtgggttt tctaggcgct ggaacgattc ttattacaga taaaaagaaa
    73261 attacaggtc tgacaactgc agcaggcatt tgggcttcgg caggaattgg attagctatt
    73321 ggagtaggtt tttatgaggg agctctttta gtagccattt ctgtttgggg tgtgatatcc
    73381 atgttccaac cactaaaaaa atatctgcaa aatcgttcta aaatgattga attgtatata
    73441 gtggttaaat ctacagaagc ctataatcgt gtattggttt attgtgcaga aaatggtatc
    73501 agaatgaccg attcaagaac agcgtttgga gatgttaatt ctgacagaat tgaatacttt
    73561 gatgttccgg acaaaaaaat agcgtcattt attactctgg aattatcagg tagatttgaa
    73621 catcttcggc tgatggaaga aattgctaat attgtaggtg ttatttatgt cgaagaaatt
    73681 agctgaaatt tagtaaacaa agggacagat gtttttgtcc ttttgctttt tagatgtttt
    73741 aatcatctaa tttttgagta gatttttgct cagaggtttt tatgaaagat tataaaatca
    73801 attttgattt aggtaaaata gaatattttg ataataattg tttgatacaa gtatacaaat
    73861 ttatttcttt ttatgatatt tgtgaaatgg tgtttgcctt tcatttacct cctgatgagt
    73921 tgataacaaa tgttatcttt aaagaaaaaa ttaactctat gttaaaatgt tacattgaca
    73981 ggctattata tgtttttata aatcctacac attttactga aaaagttaat ctacaatttt
    74041 atagcagttt tttctcatat gaatttattt gtcgtgaagt tggaaacatt cttaaaaata
    74101 aaggtgtgaa atgcaattta aacttttttg aaggggaaga atatttgtaa aattaatttt
    74161 gtgaatttgt ggatcttaaa taatttacta aattctcttg ttaaaaaaaa ttaaatattg
    74221 tatagtaata ttagaatgtt tgtaatagag gactgaaatg aaaaatataa atgggaaaaa
    74281 ggtaactatt tatgatattg cacgtttatc aggtttttct ccaaaaacag tttcacgagt
    74341 tattaatggt ggagtaaatg ttaaagaaga aacttatcaa gcgattcaaa aagttataga
    74401 ggaattgtcg tatattccaa atgcgtatgc aaaaaattta actaaaaaag aagctataaa
    74461 tatattgatt tctgtaaaaa aaatcgactc ttttccttta atttggtttc atacgctgtt
    74521 agataaagtg ttacggacgt gtaaagaatt tggtgttaat gctatagttg agtactttgg
    74581 agaggaggat acaattagta attcgattat atcaagcaca ggtagcctag tagatggtgt
    74641 tattgttttt tatgaaagtg tagatgatat cagaattcag tatttaaaga agaaccatat
    74701 gccttttctt gttttcggtg aatctcaaac gtctggagta gtctatgtat ctaataataa
    74761 ttttcaagct acttatgata tgatgaaagc tgtaactgaa gaaaaattta aaaatatgtg
    74821 gttgcttatg ggaggagaat ctcatgttaa taaggatcgt gaaagaggtg tgcgttcttt
    74881 tctgaatgat aaaaattact ttatggattt aaaagtcatt tatggattat ctacaattga
    74941 ttcagtttat tcttatgcaa tgcagcactt gactacccaa aattatccgg acattatttt
    75001 tgtttcagga gatgaaaagg ttcagggctt gattcgtgcg tgctatgaga aaggaattct
    75061 tattccagat gatatttcta ttattggatt tgataatatt cctatttctc agtattatac
    75121 tccagctttg tctacaattg ctcccaatta tgttaaattg gctaaagaaa tgatagaagg
    75181 tgttttagca attattaaag gggaaagtgt cacatctgtt gaagtttctc ctaaatttgt
    75241 taggagacag agtttctagt attgtttaat tcttgaaaat cctagtggaa aagatggagt
    75301 gttctaaaat aagttctgtt tagcctccat tcagtttcta ttgagttgga tccaatttct
    75361 aacaagtggg acatgttcat gttcgatcta aggaagacat ggtcacattc gaatgatatt
    75421 ttcaaaaaaa tcgtaaaaaa gtcttgacaa agaaaaaaca aagtattaaa ataagttcaa
    75481 caaatcagaa aagtaactat ttttgatctt cagggagcct gtggtggttg tgaataggtg
    75541 gttggaagta gtgaaagtgg gctgattttg aaaatgaatt tgaaataatg aaaattcggt
    75601 gcgcacacct tacagtgcag cttgttgtta aacaaggcag agatgtaaag ggatagtccc
    75661 tttataattg aggtggcacc gcgttaccaa cgccctcaca cggaagtata ttctgtgtgt
    75721 gggctttttt ctatccgtcg tttggtttat cttttattag ggccttaagt cgctttgatg
    75781 aacttgagtt ctatctacag ctccttgcct actactaaaa gcaaacaaaa aggctggact
    75841 aatacgaaaa aagctagtaa tactcaatga aaatcaaaga gcaaactagg aaactagccg
    75901 caggctgctc aaaa
//
LOCUS       DBEJZV010000007        73020 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.07, whole genome shotgun sequence.
ACCESSION   DBEJZV010000007 DBEJZV010000000
VERSION     DBEJZV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 73020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73020
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.07"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            16..333
                     /locus_tag="ACL3S0_000553"
                     /pseudo
     CDS             16..333
                     /locus_tag="ACL3S0_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            330..548
                     /locus_tag="ACL3S0_000554"
     CDS             330..548
                     /locus_tag="ACL3S0_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311518.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(605..847)
                     /locus_tag="ACL3S0_000555"
     CDS             complement(605..847)
                     /locus_tag="ACL3S0_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGR1311519.1"
                     /translation="MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(943..1878)
                     /locus_tag="ACL3S0_000556"
     CDS             complement(943..1878)
                     /locus_tag="ACL3S0_000556"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGR1311520.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            1982..2425
                     /locus_tag="ACL3S0_000557"
     CDS             1982..2425
                     /locus_tag="ACL3S0_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGR1311521.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2541..2807
                     /locus_tag="ACL3S0_000558"
     CDS             2541..2807
                     /locus_tag="ACL3S0_000558"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGR1311522.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            2804..3178
                     /gene="crcB"
                     /locus_tag="ACL3S0_000559"
     CDS             2804..3178
                     /gene="crcB"
                     /locus_tag="ACL3S0_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR1311523.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3172..3501
                     /gene="crcB"
                     /locus_tag="ACL3S0_000560"
     CDS             3172..3501
                     /gene="crcB"
                     /locus_tag="ACL3S0_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR1311524.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            3620..3967
                     /gene="rplS"
                     /locus_tag="ACL3S0_000561"
     CDS             3620..3967
                     /gene="rplS"
                     /locus_tag="ACL3S0_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGR1311525.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            4009..4080
                     /locus_tag="ACL3S0_000562"
     tRNA            4009..4080
                     /locus_tag="ACL3S0_000562"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4042..4044,aa:Arg,seq:cct)
     gene            complement(4247..5245)
                     /locus_tag="ACL3S0_000563"
     CDS             complement(4247..5245)
                     /locus_tag="ACL3S0_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003712 - transcription coregulator
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HGR1311526.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(5288..6094)
                     /gene="yidA"
                     /locus_tag="ACL3S0_000564"
     CDS             complement(5288..6094)
                     /gene="yidA"
                     /locus_tag="ACL3S0_000564"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGR1311527.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(6107..7411)
                     /locus_tag="ACL3S0_000565"
     CDS             complement(6107..7411)
                     /locus_tag="ACL3S0_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGR1311528.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLAE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSLIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            7483..7860
                     /locus_tag="ACL3S0_000566"
     CDS             7483..7860
                     /locus_tag="ACL3S0_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGR1311529.1"
                     /translation="MKIRMRNTIQFDEQLEVIDRLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            7951..8283
                     /locus_tag="ACL3S0_000567"
     CDS             7951..8283
                     /locus_tag="ACL3S0_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGR1311530.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            8295..9866
                     /gene="ffh"
                     /locus_tag="ACL3S0_000568"
     CDS             8295..9866
                     /gene="ffh"
                     /locus_tag="ACL3S0_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGR1311531.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVCHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(10061..11344)
                     /locus_tag="ACL3S0_000569"
     CDS             complement(10061..11344)
                     /locus_tag="ACL3S0_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGR1311532.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(11598..12311)
                     /gene="rsmG"
                     /locus_tag="ACL3S0_000570"
     CDS             complement(11598..12311)
                     /gene="rsmG"
                     /locus_tag="ACL3S0_000570"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGR1311533.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12405..12965
                     /locus_tag="ACL3S0_000571"
     CDS             12405..12965
                     /locus_tag="ACL3S0_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGR1311534.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            12967..13866
                     /gene="htpX"
                     /locus_tag="ACL3S0_000572"
     CDS             12967..13866
                     /gene="htpX"
                     /locus_tag="ACL3S0_000572"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGR1311535.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(13910..15469)
                     /locus_tag="ACL3S0_000573"
     CDS             complement(13910..15469)
                     /locus_tag="ACL3S0_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1311536.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRLLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(15708..16025)
                     /locus_tag="ACL3S0_000574"
     CDS             complement(15708..16025)
                     /locus_tag="ACL3S0_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR1311537.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYDHVKHVLSLYGPV
                     FEF"
     gene            16195..16737
                     /locus_tag="ACL3S0_000575"
     CDS             16195..16737
                     /locus_tag="ACL3S0_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGR1311538.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16737..17366
                     /gene="nth"
                     /locus_tag="ACL3S0_000576"
     CDS             16737..17366
                     /gene="nth"
                     /locus_tag="ACL3S0_000576"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGR1311539.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            17577..18098
                     /gene="pyrR"
                     /locus_tag="ACL3S0_000577"
     CDS             17577..18098
                     /gene="pyrR"
                     /locus_tag="ACL3S0_000577"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGR1311540.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            18117..19040
                     /locus_tag="ACL3S0_000578"
     CDS             18117..19040
                     /locus_tag="ACL3S0_000578"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGR1311541.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            19090..20169
                     /locus_tag="ACL3S0_000579"
     CDS             19090..20169
                     /locus_tag="ACL3S0_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGR1311542.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            20482..23658
                     /gene="carB"
                     /locus_tag="ACL3S0_000580"
     CDS             20482..23658
                     /gene="carB"
                     /locus_tag="ACL3S0_000580"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGR1311543.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(23933..24742)
                     /locus_tag="ACL3S0_000581"
     CDS             complement(23933..24742)
                     /locus_tag="ACL3S0_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR1311544.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPHYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(24744..25547)
                     /locus_tag="ACL3S0_000582"
     CDS             complement(24744..25547)
                     /locus_tag="ACL3S0_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR1311545.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(25557..27044)
                     /gene="tacF"
                     /locus_tag="ACL3S0_000583"
     CDS             complement(25557..27044)
                     /gene="tacF"
                     /locus_tag="ACL3S0_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGR1311546.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            27380..28087
                     /locus_tag="ACL3S0_000584"
     CDS             27380..28087
                     /locus_tag="ACL3S0_000584"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGR1311547.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            28092..29114
                     /locus_tag="ACL3S0_000585"
     CDS             28092..29114
                     /locus_tag="ACL3S0_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGR1311548.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            29131..30000
                     /gene="licA"
                     /locus_tag="ACL3S0_000586"
     CDS             29131..30000
                     /gene="licA"
                     /locus_tag="ACL3S0_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGR1311549.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            29990..30868
                     /locus_tag="ACL3S0_000587"
     CDS             29990..30868
                     /locus_tag="ACL3S0_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR1311550.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            30880..31569
                     /locus_tag="ACL3S0_000588"
     CDS             30880..31569
                     /locus_tag="ACL3S0_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGR1311551.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            31666..32514
                     /gene="dprA"
                     /locus_tag="ACL3S0_000589"
     CDS             31666..32514
                     /gene="dprA"
                     /locus_tag="ACL3S0_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGR1311552.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            33398..34441
                     /locus_tag="ACL3S0_000590"
     CDS             33398..34441
                     /locus_tag="ACL3S0_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGR1311553.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEHFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            34608..36695
                     /gene="topA"
                     /locus_tag="ACL3S0_000591"
     CDS             34608..36695
                     /gene="topA"
                     /locus_tag="ACL3S0_000591"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGR1311554.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            36801..37160
                     /locus_tag="ACL3S0_000592"
     CDS             36801..37160
                     /locus_tag="ACL3S0_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGR1311555.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            37253..37885
                     /locus_tag="ACL3S0_000593"
     CDS             37253..37885
                     /locus_tag="ACL3S0_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGR1311556.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            37929..38585
                     /locus_tag="ACL3S0_000594"
     CDS             37929..38585
                     /locus_tag="ACL3S0_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGR1311557.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            38655..39698
                     /locus_tag="ACL3S0_000595"
                     /pseudo
     CDS             38655..39698
                     /locus_tag="ACL3S0_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            39710..40746
                     /gene="leuB"
                     /locus_tag="ACL3S0_000596"
                     /pseudo
     CDS             39710..40746
                     /gene="leuB"
                     /locus_tag="ACL3S0_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            40743..41012
                     /locus_tag="ACL3S0_000597"
     CDS             40743..41012
                     /locus_tag="ACL3S0_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGR1311558.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            41016..41375
                     /gene="leuD"
                     /locus_tag="ACL3S0_000598"
     CDS             41016..41375
                     /gene="leuD"
                     /locus_tag="ACL3S0_000598"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGR1311559.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            41537..42105
                     /locus_tag="ACL3S0_000599"
                     /pseudo
     CDS             41537..42105
                     /locus_tag="ACL3S0_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004915491.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            42199..42264
                     /locus_tag="ACL3S0_000600"
                     /pseudo
     CDS             42199..42264
                     /locus_tag="ACL3S0_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42427..44358
                     /locus_tag="ACL3S0_000601"
     CDS             42427..44358
                     /locus_tag="ACL3S0_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGR1311560.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKV
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIGPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            44345..45661
                     /locus_tag="ACL3S0_000602"
     CDS             44345..45661
                     /locus_tag="ACL3S0_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGR1311561.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKEWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            45836..46822
                     /gene="guaC"
                     /locus_tag="ACL3S0_000603"
     CDS             45836..46822
                     /gene="guaC"
                     /locus_tag="ACL3S0_000603"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGR1311562.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPTKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            46886..46957
                     /locus_tag="ACL3S0_000604"
     tRNA            46886..46957
                     /locus_tag="ACL3S0_000604"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46919..46921,aa:Arg,seq:ccg)
     gene            47140..47838
                     /gene="rnc"
                     /locus_tag="ACL3S0_000605"
     CDS             47140..47838
                     /gene="rnc"
                     /locus_tag="ACL3S0_000605"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGR1311563.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            47829..51368
                     /gene="smc"
                     /locus_tag="ACL3S0_000606"
     CDS             47829..51368
                     /gene="smc"
                     /locus_tag="ACL3S0_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGR1311564.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            51365..52159
                     /locus_tag="ACL3S0_000607"
     CDS             51365..52159
                     /locus_tag="ACL3S0_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR1311565.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYRGQDLYEATMSREFYLTTFEKLKTSPYV
                     DINKLLLTGKKGAYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGIIMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            52159..52977
                     /locus_tag="ACL3S0_000608"
     CDS             52159..52977
                     /locus_tag="ACL3S0_000608"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR1311566.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            52981..54201
                     /gene="ftsY"
                     /locus_tag="ACL3S0_000609"
     CDS             52981..54201
                     /gene="ftsY"
                     /locus_tag="ACL3S0_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGR1311567.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQAEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(54245..55732)
                     /gene="zwf"
                     /locus_tag="ACL3S0_000610"
     CDS             complement(54245..55732)
                     /gene="zwf"
                     /locus_tag="ACL3S0_000610"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGR1311568.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(55881..56621)
                     /locus_tag="ACL3S0_000611"
     CDS             complement(55881..56621)
                     /locus_tag="ACL3S0_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR1311569.1"
                     /translation="MAKLKIDVNDLHKYYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(56621..58786)
                     /locus_tag="ACL3S0_000612"
     CDS             complement(56621..58786)
                     /locus_tag="ACL3S0_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR1311570.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQSTKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            58959..59912
                     /locus_tag="ACL3S0_000613"
     CDS             58959..59912
                     /locus_tag="ACL3S0_000613"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGR1311571.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            59989..61977
                     /gene="uvrB"
                     /locus_tag="ACL3S0_000614"
     CDS             59989..61977
                     /gene="uvrB"
                     /locus_tag="ACL3S0_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGR1311572.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMTYNEEHDIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKVLD"
     gene            61987..62550
                     /locus_tag="ACL3S0_000615"
     CDS             61987..62550
                     /locus_tag="ACL3S0_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR1311573.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            62516..63004
                     /locus_tag="ACL3S0_000616"
     CDS             62516..63004
                     /locus_tag="ACL3S0_000616"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311574.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIDDLKVVGFISYGSFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LVKVALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            63077..63544
                     /locus_tag="ACL3S0_000617"
     CDS             63077..63544
                     /locus_tag="ACL3S0_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR1311575.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFTGTLQS
                     SEEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(63541..64056)
                     /locus_tag="ACL3S0_000618"
     CDS             complement(63541..64056)
                     /locus_tag="ACL3S0_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGR1311576.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(64068..64595)
                     /locus_tag="ACL3S0_000619"
     CDS             complement(64068..64595)
                     /locus_tag="ACL3S0_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR1311577.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(64877..65440)
                     /locus_tag="ACL3S0_000620"
     CDS             complement(64877..65440)
                     /locus_tag="ACL3S0_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR1311578.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(65424..65975)
                     /gene="coaC"
                     /locus_tag="ACL3S0_000621"
     CDS             complement(65424..65975)
                     /gene="coaC"
                     /locus_tag="ACL3S0_000621"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGR1311579.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(65987..66676)
                     /gene="coaB"
                     /locus_tag="ACL3S0_000622"
     CDS             complement(65987..66676)
                     /gene="coaB"
                     /locus_tag="ACL3S0_000622"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGR1311580.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            66906..68576
                     /locus_tag="ACL3S0_000623"
     CDS             66906..68576
                     /locus_tag="ACL3S0_000623"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGR1311581.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCALIDVPVELASVWADGVEGGVELAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQVVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            68904..70079
                     /gene="mutY"
                     /locus_tag="ACL3S0_000624"
     CDS             68904..70079
                     /gene="mutY"
                     /locus_tag="ACL3S0_000624"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGR1311582.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            70135..70839
                     /gene="yycF"
                     /locus_tag="ACL3S0_000625"
     CDS             70135..70839
                     /gene="yycF"
                     /locus_tag="ACL3S0_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGR1311583.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            70832..72181
                     /gene="vicK"
                     /locus_tag="ACL3S0_000626"
     CDS             70832..72181
                     /gene="vicK"
                     /locus_tag="ACL3S0_000626"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGR1311584.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     LLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            72183..72992
                     /locus_tag="ACL3S0_000627"
     CDS             72183..72992
                     /locus_tag="ACL3S0_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR1311585.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
BASE COUNT        22173 a        13105 c        16028 g        21714 t
ORIGIN      
        1 ttataaaaag gagtgtggat gaacgccttt ttagaagagc tttcacaagc ttatcctttt
       61 actcgttatg gacaatgcta tatggcataa atcaagtacc ttaaatattc cgactaatat
      121 tgattttacc tttattcctc catacacacc agagatgaac ccattgaaca agtgtggaaa
      181 gagattcgta aacgtggatt taagaataaa gcctttcgaa ctttggaaga tgtcatgaat
      241 caacttcaag atgtcataca aggactggag aaggaggtga taaagtccat cggtaatcgg
      301 agatggacta gaatgctttt tgaaagcaga tgagtataag tcctcgtttt gaaaccttag
      361 agcaggccat tgcctccaaa gatttggaaa aagtccgaga agcttttaag aaaatgaatt
      421 ccacttggac catcaatgaa agtgtggttc gtgacaatag tatagctcat tatggacgtg
      481 ttgaaacagc tatttccttc ctgcctagta gcatggaaat cgaacctaca gatgagtctg
      541 gaacatgaaa acagcagttg atttcaagaa acaaaaaaga acagccaaaa ctgttctctt
      601 atcattattt gagaccgtat tttttgttga aacgatccac gcgtccatct gcttgagtga
      661 acttttgacg tccagtgtag aatgggtgtg agtctgatga aatttccaca cggatcaatg
      721 ggtaagtttc gccttcgaac tcaactgttt cgttagagcg ttttgttgaa ccgctaagga
      781 attggtaacc agtagttgtg tccatgaaga caactgggcg atattctgga tggatatctt
      841 ttttcatttt gcaatatttc ctttctgcca tggtctcttt gcgagccata gattgttact
      901 atactagtct atcagattct gaaaagtttg gcaagtattt tatcagtttt taagcaagtt
      961 ttttaacttt tggtagatga tttcgttttc ttctaggcta taggaattag caccacttgc
     1021 tagagggtgg cctccaccat catgctcctt ggcaatttca ttgataggat ggactttact
     1081 gcgtaagcga actcggtagt ggccatcagc ctgttcgaca aaaattcccc agagactcac
     1141 tctgtcaatg cgtccaggtg cacctacaat ggccgcagtt tcagcatcgg ttatattgta
     1201 ttgtttcaag attttctgac tcaggataac gcgagcagca ccattttcat ccacttccag
     1261 atggtcgtag atgtagcctt gcagtttagc aattttgtag ctcatagtgt ccattttgcg
     1321 agtgagagcc gcaaagtcaa agttatgttc tctcaaataa gcagccaggc gaagagtccg
     1381 tgcagtggta gaagggtaga ggaagcgacc tgtatcaccg acaattcctg caaagagcaa
     1441 ctcagcatcg cgatctgcca aggctagttg ggttgtttgg gcaaataggg taatcatctc
     1501 gctagcgcta cttgaactag tatcgaccca agacaggtca ccgtatacat catcatttgg
     1561 atggtggtca atcttaatga gaaaatcacc ttgactatag cgcttatcat cgatacgagc
     1621 agtattagct gtatcacaga cgatgacaag tgcgccttgg taggctctat cttcaacaag
     1681 atccatctca gccatccaag taagagttgg ttcatcaaaa ccgacggctt tgatggtttt
     1741 ttctgggaaa tgatgttcta gcaaggcttt caatcccacc tgacttccca aggcatcagg
     1801 gtctggtttc atatgacgat gaatgataat ggtgtcgtat tctttaattt tttctaaaat
     1861 ttgttggcaa atctccataa ataacctcaa ttctttctca tttcattgta gcacaagaat
     1921 ttttattttt aaaatgaaaa agatgtgata taatggagaa agataaattg aggaggacga
     1981 tatggcatta gcaaaaattg tatttgccag tatgaccggt aataccgaag aaattgcaga
     2041 tattgtagca gacaaattac gtgacttggg cttggatgtt gatgttgatg aatgtacaac
     2101 tgttgacgct tcagacttct tggaagcaga catcgctatc gttgcgacct atacttatgg
     2161 tgatggtgaa ttgccagatg agatgatgga cttctacgaa gacctagcag atctcaactt
     2221 gaatggcaaa atctacggag tggtcggctc aggagatacc ttctacgatg aattttgtaa
     2281 ggctgttgat gactttgacc gtgtctttgt gtcaacagga gcagaaaaag gttcagagtg
     2341 tgttaaagtt gatctttctg ccgaggaaga agatattgaa cgcttggaac aattcgcaga
     2401 agaattggct gctaaagtag gataagcata aaagtgcgct gatgtaatca atcagtgcat
     2461 ttttcttatc gagagttggg attttactag cctaattgat ggctttttga tacaataatt
     2521 caaataaagg aggagactgt atggatttag atattattcg tcaagaaatc gatcaaatcg
     2581 acgaccaaat tgtcaaactg ttagaagaac gaatgcactt agttgaagga gttgtcgctt
     2641 ataagaaggc ttcagggaaa ccgattttag atactaagag agaagcagtt atttttgaaa
     2701 aggttagaag tcgtgtagag gacaagcgct atcaggagac tattgtcgcg actttttcgg
     2761 acatactcaa acgttcgcgt gattatcagg atcaaaatat caaatgaaaa aagaacaatt
     2821 ttatccgcta gggatttttc tagctgctat gttgggcgga cttgtccgct acctagtttc
     2881 cacttggtta ccagccagtc cagatttccc ttggggcact ctctttgtca actatctggg
     2941 aattttctgc ttgatttatc ttgtcaaggg ctatctggtc tataagggga ctagtaaggg
     3001 cttgatttta gcactgggga cgggtttttg cggaggttta acaacttttt ccagcctaat
     3061 gcttgatact gtgaagctgc ttgatacagg gcgttatctt agtttgatac tgtatttgct
     3121 tttgagtatc ggtggaggcc tgcttttagc ttactatttg gggaggaaga aatggtaatc
     3181 gtctatcttg caatcgcctg tggcttggga gcactcgtac ggtatttctt ttctcgctat
     3241 aatcaagctt ctaaattgcc actcggaacg ctcatagcta atcttttagg ttgtttttta
     3301 attggagtat tctacaatca tgtagagtct aaggaagtat atgctattct agcaacagga
     3361 ttttgtggcg gtttaacaac tttttcgacc ttgaatgacg aacttcaaag actgctaagt
     3421 gataagaagg tcttttattc ttacctgact ttgacttaca taggtggttt ggttgcgatt
     3481 tttttaggaa ttttgctata aatttcttta cttttttgtg aaaatttggt aaactgtatc
     3541 ttgtgtgtaa tggacgcaca agaatacagt ttatccgctg aggaagtttc ctcaagattg
     3601 acaaagatag gagaataaaa tgaatccatt aatccaaagc ttgactgaag gtcaacttcg
     3661 tacagatatc ccatcattcc gtcctggtga cactgttcgt gtacacgcga aagttgtcga
     3721 aggtaaccgt gaacgtatcc agatttttga aggtgttgtt atcgcacgta aaggtgctgg
     3781 aatctcagaa aactacacag ttcgtaaaat ctctaacggt gtaggtgttg agcgtatctt
     3841 cccaatccac actccacgtg ttgaaaaaat cgaagttgtt cgttacggta aagtacgtcg
     3901 tgcgaaattg tactacttgc gtgctcttca aggtaaggca gctcgtatca aagaaatccg
     3961 tcgttaattc gactaaaaaa ctctgctttt cagcagagtt tttatctagc tcccttagtt
     4021 caatggatat aacaactccc tcctaaggag tagttgcagg ttcgattcct gcagggggca
     4081 tgtaattaga tatcaaagaa gtttgtcaaa aagtctttga tattaaaaga acgcataata
     4141 taggggattg tctccataat attatgcgtt ttattattga aaaatttggg caatcatcag
     4201 ataaaattga gactatatcg agtatataaa tgtttgtata gtcaatttat tcaaaatcgt
     4261 caagttctaa attatttaaa ggactataac attcatattt ctttaagtaa ttgtttattt
     4321 cttcagcagt ggaacgaggt aaattaactc ttaaatagtc aatatcttcc ttagataaaa
     4381 aatgatttgc attcaaaatt gagaagcgaa ataatgcttc atcaaaagca aaatcataat
     4441 cgtcatcaga taatgattcc attaatgttt gaatatgttt tagtgagtag tcaggtatcg
     4501 aatcgggata atatactgga taatcagtgg ctgaaaaatt gttttctaat cctgaaatag
     4561 taattatcaa agattctatg taatatatta aagcatgttt aatattacct tcttgttcca
     4621 aatgtcttcc ctgagccttt cgtgtgttag ataagcatcc aaaatctcct gatacagtat
     4681 tcctatgagc ttgtttattt aagagactcc attttatatc accaaaagtt gctttaaaag
     4741 agatattgtt tttttcttta caataatctt ccatagttat gtctttatca tagtatgctt
     4801 tgatatagtc actatgttcg ataataagat tttgtgcttc ttttgttagt ttaaattcga
     4861 acggaatatc taaattgtca atgttaacat tattaattat tcttgtaatt aattctgctt
     4921 tttttccaga agtagctaaa ttatgtttag ataatatagt ttttaattct actactgtaa
     4981 gatatgataa agtcttattt ttagtgaagt atcctaattt gtataattga ttgtgtgtag
     5041 attcagggtc aatttgaaga gagtatttaa aatatcttgg gaaattataa tttctccctg
     5101 ttttttgagt ccaatctatg agtatgagtt gcccaggagt aaggccacat tctaattcgt
     5161 ttaggtaaaa attgttacaa tcagaatttg tgtctctatt atgattattt tgttttaaat
     5221 taaatagttt gctaaaaaaa ttcattggat tttattgcta atcaattctt attgaaaaat
     5281 gatactttta cagtacccat gttcggatgg cgtgggcaac gccggattcg tcatttgttt
     5341 tagtgatgta tttggcgatt tttttgattt ctggatttcc attttccatg acaacggggt
     5401 ttccaacgac ttccagcatg gcacggtcat tttcttcgtc accgattgcc atggtttcat
     5461 ctttggtcaa tccgagtttt tcagccaagt gagtaatggc tgaacccttg tctacattct
     5521 ttgtaaggag ttcgaggtag aaaggagcag atttgttgat ggagtagcgc tcgtaaaatt
     5581 ctgctggaat tttttcaatc gcagcatcga gaatttctgg ttcatcgata aacatacatt
     5641 taacaatttc tttgccagcc atttcttcag gggtacggta gaagataggc atgctgacga
     5701 gggttgattc gtgtacagtg tattttccga tattgcgatt tgcagtatag ataccgtcct
     5761 tggtaatggc atgcatgtgg acaccgagct tgcgactgag gaattccata tccagataat
     5821 cctcataggt caaggattcg ctgataatct catggccagt agcagtttct tggacaaggg
     5881 caccattgaa ggtcaccaca tagtcacctt ggtctctcaa ctgcaagtcg tccagaagtt
     5941 tggcaacacc tgcgatgggg cggccagttg caatcacgac tttgacacca gcttctttgg
     6001 catcttggat ggcagaaaag acttcaggag tgatttcctt ttggctgttg actagggttc
     6061 cgtcaatatc gacggcaatt agtttaatac tcataaattt cctcttctag tttttatttg
     6121 gggtaaaatg atcgttctca atcaagtgta aaaattgctg ggtaatgctt gcgaagatgc
     6181 tgttttggtc taacatttct ttagggaaat agaaacgatt atctccgtgg cgactgccag
     6241 caagggattg gacgataaga gacaggctag agagttcggc cagttctcca tttttttgta
     6301 aaatctcaat ctgtgtccgt gggttttcag attcgggacg atagatatca taagggaggt
     6361 caaagttctt atgaatggca gtgtagtagt cgggatcaaa gccgatatcc tcagctaatt
     6421 ttctcatgct ggcgagttgg tcttggtcct cttgtgaaaa ggtaatggat ttaaagacct
     6481 tgcggttgac aaagcgttgt gacaagtctg cgagaatctt gtcaggactg gtcatccaga
     6541 gttgaaagta ggtattcatc acaccatcat ctagagccag atagtcagtc aaggtcacat
     6601 ttttttcaaa gaaaggcagg aggtgtggag aagttcgtgc aaagaagtcc ttgtcttcag
     6661 gatagagttc cttggcgcgt ttgagaagat tctgtaggag aacttccatg gcgcgtgttg
     6721 cggggtggaa ataaacctgc atgtacatct ggtagcgact gaggacgtag tcttcgatgg
     6781 cgtgcatgcc attgcgctga aaggcgatac cattttcgat aggacgaatg actcggagga
     6841 ttcgagtcag gtcaaattcc ccataggatg ctcctgtaaa ataggagtca cgcaagagat
     6901 agtccatgcg gtccgcatca atctggctag aaatgagctg cacgacctgc ttattaggat
     6961 aggtatggtc aatgacactg gccacctttt ctgggaaatc aggtgccact tgtagcagga
     7021 cttggtgaat ctctgtctca ggattttgaa taatctcctg agtaatggct tcatggtctg
     7081 tatcaaagag attttcaaaa gtatgggagt aggcaccatg cccaaggtcg tgtaggagag
     7141 cagcggtcat ggtcaagaga gactcggcag gattccattc ctcaggatat ttttcttcga
     7201 aaatctctgt gatgcgtcgt gcaatttcat agactcctag acagtgagag aagcggctgt
     7261 gctctccacc gtggaaggta taactggagg ttcccagttg cttgatacgg cgcaaacgct
     7321 gaaattcttt tgtattaatc aagtcataga taatttgatt attgacatgg atgtagttgt
     7381 gaactgggtc acggaatact ttttcgttca tatgaccatt atagcaaaat cctgctcttt
     7441 ttggtaaaat agtaggacaa gagacaagaa agagggcctg atgtgaagat tcggatgcga
     7501 aatacaattc agtttgatga gcagttggaa gtgattgacc ggctttatga tgtggaagtg
     7561 catgaaaaag gagattatag ctacctgctt ttctataatg aggaaaagga aaaagtagtg
     7621 attaaatttc atggtcaaga acttgtgatg agccgatttt ctaatcccaa gaccattatg
     7681 cgctttctaa aggatagcga tagtttagcc tatattccta cacctatggg catgcaggag
     7741 tttatcatcc aaacgagcca ttatcaagtt gataggcaaa agattgaact agattatcaa
     7801 ctacaaaatc aagagggaca tccttttgcc agctatcaat tggaaattac ttggggctag
     7861 gctcatgtct ttttcaaatt tagctatcta tcttcttgga tcggcttcct agtgtggtag
     7921 attaggctaa tttttggtat aataaaagtt atggaaatcg aaaaaaccaa tcgtatgaat
     7981 gcgctctttg aattttatgc ggcgcttttg acagataagc aaatgaatta tatcgagctc
     8041 tactacgctg atgattacag ccttgctgaa attgccgagg agtttggtgt cagtcgtcag
     8101 gctgtctatg acaatatcaa gcgaacagaa aagattctgg aagattatga gatgaaattg
     8161 cacatgtact cggactatat tgtccgcagt cagatttttg atcagatttt ggagcgctat
     8221 cccaaggatg actttctgca ggagcagata gaaattttaa caagcattga taatagagaa
     8281 taagaggaag aaaaatggca tttgaaagtt taacagaacg tttgcagaac gtctttaaaa
     8341 atctacgtaa aaaaggaaaa atctctgaat ctgatgtcca agaggcaacc aaagaaattc
     8401 gcttggcctt gctcgaggcc gacgttgcct tgcctgttgt aaaggacttt atcaagaaag
     8461 ttcgcgagcg tgcagtcggg catgaggtca ttgatacact taatcctgcg caacagatta
     8521 ttaaaatcgt tgatgaggaa ctgacagccg ttttaggttc tgatacggca gaaattatca
     8581 agtcacctaa gattccaacc atcatcatga tggttggttt gcagggagct ggtaaaacaa
     8641 cttttgcagg taagctggct aacaaactca agaaggaaga aaatgcccgt cctttgatga
     8701 ttgcggcgga tatttaccgt cctgctgcca ttgatcagct gaagacactg ggacaacaga
     8761 ttgatgtgcc ggttttcgct cttgggacag aggttccagc tgttgagatt gtacgtcaag
     8821 gtttggagca agctcaaact aatcataacg actatgtctt gattgatact gcgggtcgtt
     8881 tgcagattga tgagctcctc atgaatgagc ttcgtgatgt gaaagcattg gctcaaccaa
     8941 atgaaatctt gcttgtcgtt gatgctatga ttggtcagga agcagccaat gttgcgcgtg
     9001 agtttaatgc tcagttggaa gtgactgggg tcatccttac caagattgat ggcgatactc
     9061 gtggtggtgc tgctctgtct gtttgtcaca ttactggaaa accaatcaag ttcactggta
     9121 caggtgaaaa gattacggac attgaaacct tccacccaga ccgcatgtct agccgtatcc
     9181 ttggcatggg ggatatgctc actttgattg agaaagcttc tcaggaatac gatgaacaaa
     9241 aagcccttga aatggctgag aagatgcgcg aaaacacctt tgattttaat gatttcatcg
     9301 atcaattaga tcaggtgcaa aatatggggc cgatggaaga cttgctcaag atgattccag
     9361 gtatggccaa caatccagca cttcaaaaca tgaaggtgga tgaacgccag attgctcgta
     9421 aacgtgcgat tgtgtcttcg atgacacctg aagaacgtga aaacccagat ttgttaaatc
     9481 caagccgtcg ccgtcgtatt gctgctggtt ctggaaatac attcgtcgaa gtcaataaat
     9541 tcatcaagga ctttaaccag gctaaacagc tcatgcaggg tgttatgtct ggggatatga
     9601 ataaaatgat gaagcaaatg gggattaatc caaataacct tcctaaaaat atgccaaata
     9661 tgggaggaat ggatatgtct gcccttgaag gaatgatggg acaaggcggt atgcctgact
     9721 tatcagctct cggaggagca ggaatgccag atatgagcca gatgtttggt ggcggtttga
     9781 aaggtaaaat tggtgaattt gccatgaaac agtccatgaa acgtatggct aacaaaatga
     9841 agaaagcgaa gaagaaacgc aagtaagaca agagattgat gcaaatctca tttgatgaga
     9901 aaataaagta aaaatttcta tgataaaacg tacagtatca aggttttaga atatctgata
     9961 ttatacgttt tttgatttta ataattttgt taagacactt ttattatggt atacgaaaaa
    10021 tccactcagc tgtctgagtg gattaggtgt atttagactc ttagtcttta ttttcgtatg
    10081 gcaagatcaa gttcaagatg attcctgtca tggctgaaag ggcagtacct gaaagtgtaa
    10141 ctggaccaag tttaaggata gctcctccaa gtccaagaac caacatagca cttgcgatga
    10201 tgaggtttcg catttgagcg aaatcaacac gttctttaat caagactttc aaaccattgc
    10261 tggcgataac cccatagaga aggattgaca taccaccaag tacagcgttt ggaatagttg
    10321 aaatcaaggc agtgaattta ccaaggaagc tgagggcaat cgcgatgaag gcagcgttac
    10381 ggataactga gacagaagcg atacgagtca taccgataac ccctgtattt tctccgtaag
    10441 ttgtattggc tggtccacca aggaaggcag aaacagaagt tgcgataccg tcaccaagaa
    10501 gagtacggtg aagacctggt tcttttaaga attgacgacc acagatttga cccaaaacag
    10561 tatggtctcc gatatgttca gaaattgtta cgatagcgat tggcaagata gcgatggctt
    10621 ctggaccaaa gtaaagattg tactctttaa aggcaccacc tgtgctaaat ggcaagtaga
    10681 aaccaggaat ttcaaaccag ttagcttcta ggacaggtgt aaagtcaacc aagccaagag
    10741 ttagtgcgaa aaggtaacca ccgataatgg caaagaggaa tggaatgatt cgtaggaagc
    10801 cttttccttt tgtattgata aaggcagcaa ttaggaaagt aacaacggct accagagcat
    10861 ttttccaatt tccgtctgct acaagacctg cattggtaac agctgaacct gcaagtccaa
    10921 gaccgataac gatgatcata ggaccgataa tgattggtgg caagagttta tcaatccatt
    10981 ttgttcctac aaatcggatg ctggtagcaa caaggacata gaccaaacca gtcaagataa
    11041 cccctgtttg ggcagcagat acatcccccc ccatttcttt catagccagt gacatagctg
    11101 tgataaaggc aaatgaagaa cctagataaa ctggaacttt aaaaccagta gcaatcatgt
    11161 agatgagtgt tccaacacct gaagcaaaaa gggcaacaga tacaggcatt cccaaaatca
    11221 atggtaccaa gatggtcgca ccaaacatgg cgaaaacgtg ttggaaacta aggagaattc
    11281 cttttccatc cgaaggacgt tggtcaacgt ctagtaacaa atcaacagtt gattcttgtt
    11341 tcatataaac ctcacttttg ggcatcagaa aagagcccat tattttacag caataggccc
    11401 tcagagtaag acttctctaa aatctagact ttaaagagtt tcaaatattt ctgcgtcttc
    11461 gtcacctcac gggatgacat taaaaacctt tgcttaggat agtatagcag aaaaaaatga
    11521 ttttgtaaat cattttttcc cgagcctaaa aataagagag cgaggttgat tttgtaaata
    11581 tttttttact taaaaattta aagcgggcgt ttatttggca taccagcctt acgtggatat
    11641 ttatttggtg tttctttttt cttttctacc actgtgatgt aacgcggatc tctatttggt
    11701 agggcgtagc tgagattgtc ttcgacttta ctaaaaagga gattgagggc attcttagct
    11761 tctaacaact cctcaggcgc attgctggcc ttgagtgcca atagttttcc accaacctta
    11821 aggtagggaa tagtcaattc agataggacc tgcatacggg caaccgcacg agctgttaca
    11881 aaatcatatt gagcacggaa gttcttgtct tgggcaaaat cttcggcacg tccgtggtag
    11941 aaatgaactc cgttcaaatc cagttcttga gccaagagtt gtaggaagtt gatgcgctta
    12001 ttgagtgaat caataatggt cacatctaac tccggataga gaattttcat tggtagacta
    12061 ggaaatcctg ccccagcccc gatatcaaga agtttgatag tttcattggg aatcaaacct
    12121 tgaagaatgg gtgcaatcga atcgtaaaaa tgtttgagat aaacttcttc cttgtccgta
    12181 atcgccgtca aattaatctt ctcattccac tcgaccaaga gctcaaaata acgttcaaat
    12241 tgttcttttt gctggtccga aagtggaaga ttctgctcgg caagcaagtt gtaaaatgtt
    12301 tctggtttca tagttatttc cttctttagt atcatcttat tttaccacaa tcattaaaaa
    12361 tttgatatac tggtactaat ctaaaagtag aaaggactta tatcatgact tggattattc
    12421 ttggagttat cgctcttatt gttatttttg tgattgttag ctataacggt ttggttaaaa
    12481 atcgtatgca aaccaaggag gcttggagtc agattgatgt tcagttgaaa cgtcgaaatg
    12541 acctcttgcc aaacttgatt gagactgtaa aaggttatgc caaatatgaa ggttctaccc
    12601 ttgaaaaggt ggcagaacta cgtaaccaag tggcggcagc gacttcacca gcagaagcta
    12661 tgaaagccag tgatgccctc actcgtcaag tttcaggtat ttttgcagtt gcagaaagct
    12721 atccagattt gaaagctagt gctaactttg ttaaattgca agaggagttg acaaacacag
    12781 aaaataaaat ttcttactct cgtcaactct ataacagtgt tgtcagcaac tacaatgtaa
    12841 aattagaaac tttcccgagc aatattatcg ctggaatgtt tggatttaaa gcggcagatt
    12901 tccttcaaac acctgaagag gaaaagtcgg ttcctaaagt tgattttagc ggtttaggtg
    12961 actaagatgt tgtttgatca aattgcaagc aataaacgaa aaacctggat tttgttgctg
    13021 gtatttttcc tactcttagc tcttgttggt tatgcggttg gttatctctt tataagatct
    13081 ggacttggtg gtttggttat tgcactgatt atcggcttta tctacgcttt gtctatgatt
    13141 tttcaatcga cagagattgt catgtccatg aatggagcgc gtgaggtgga tgagcaaacg
    13201 gcaccagacc tctaccatgt agtggaagat atggctctgg tcgctcagat tcctatgccc
    13261 cgtgttttca tcattgatga tccagcctta aatgcctttg cgacaggttc taatcctcaa
    13321 aatgcggctg ttgctgcgac ttcaggtcta ctagctatca tgaatcgtga agaactagaa
    13381 gctgttatgg gacatgaagt cagtcatatt cgtaattatg atatccgtat ttcgactatt
    13441 gcagttgccc ttgctagtgc tatcaccatg ctttctagta tggcaggtcg tatgatgtgg
    13501 tggggtggag caggtcgcag acgaagtgat gatgaccgag atggaaatgg tcttgaaatc
    13561 attatgctag tggtttccct actagctatt gtactggcac ctctcgctgc aaccttggtt
    13621 cagctcgcta tttctcgtca gagggaattt ctggcagatg catctagtgt cgagctgact
    13681 cgcaatcccc agggaatgat taatgcccta gataagttgg acaatagcaa acctatgagt
    13741 cgccacgtcg atgatgctag cagtgccctt tatatcaatg atcctaagaa aggtgggggg
    13801 ttccaaaaac tcttttatac ccacccacct atctcagaac ggattgaacg tttaaaacag
    13861 atgtaaaaga atccagaggt cgtctctgga tttttgctat gttgcaaatt tataaatctt
    13921 ctaaattaac tagcttcaaa ccgtgttctg tcatgcgata gatgatcgag cagacttctt
    13981 ttaataaacg acggtcatgc gaaacagtga tgagaccgcc tggataggta gcaaagagtt
    14041 ttctgatttg gggttgagaa gtgggagaaa agtttcgtgt gggttcatcc agcaggagaa
    14101 agtttggttt gcgcaggact aaatccaaaa gcaggagttt tccctgttgt ccgccagata
    14161 aggagcgaat ttgatgctgc atttctggat aactgaaatt gagactagct aggtgagatt
    14221 ggattttctg tagttcctct ttttccccag ttttactgag ataggctatt ggggataaat
    14281 ccaattgcag ttttttgtgg taatcttgtg gcataaaacc aagtgaaatc tctcttttat
    14341 cattcagaag tctctgtaac ttggctaaca gagttgattt cccaacacca tttggcccga
    14401 taataccgat tttttcttgg ccacggacag ttagttgtag tttttgaacc aaaactcggt
    14461 cgtcaatgga caaattttct ttttccagtt ggactaagac tttagaagct ggtaatggtt
    14521 ggatgtctga aaagaaaagt tggatttgtt cctcttcaag tggcttttga gtcatggact
    14581 gagctgcctt ttcgtagcgt ttttcttgtg agaggacagt tttcatcttt ttagccaata
    14641 ggcgaccggc agtactatct ttggtagctc gaagcgcagt ttctacattt tgcttaactc
    14701 tccgatgttt ttccatggtt ttatcgtagg ctctttggtt gttagcagct tgctgacttt
    14761 gtttggcaaa attagccttt ctctgctcac tatagctatc atagtctaaa tgctctacta
    14821 gcgtttccgc ttctttacgg tgtttgacca gtcgcaagtg aacaatagtg tctgccgttt
    14881 cagaaagaaa gtcttcatca tgggaaatga aaataacggt ttgcctggtc ttttgaatct
    14941 ggccttttag ccaatcaact gtctcaaggt ctaggtcatt tgaaggttca tctaaaaata
    15001 gaatctcaaa gggtttggct aactcatgga taagctgaat tttcaaagct tcgccccctg
    15061 atagattgcc aatctcttgg tcacttgcga aacgattgct atcaaaatgc aattcctccg
    15121 ccaaacgata gaggatactg tagtctaaat caatagaatc taaaaagaag tagtcgtgta
    15181 aagttttctt ttttaggtcc tcagggactt tttgaggaat gtaggccagt gactgatagt
    15241 cagattggat gtttcccttg atagtgaaat cagacaaagc ttcccccatt aaaattttaa
    15301 gtaaggttga tttgccattt ccttcttcac caataatagc aaccttttcc ccgtcttgga
    15361 tggtcatggt taggtcagat acaagatctc gtaaatcttt gttttgtgtg atggttagat
    15421 gattgatttt tatcatatga tttccctttc tagaatgttc atagtgcata acaaaaagct
    15481 ctactttacc tagtagagcc caaagtctat gtcaaaaaaa ctctattaac atgccagaaa
    15541 aagagcataa aagagcacac aaaaagagac aaaaacaaga tctactaaat aaaggttctt
    15601 tatttgatag acttagttgt tcatgtctcc cttacctccg agtattagta tctttatatt
    15661 atacctttaa ggaaattttg tcaacagaaa actggaaatt ctatgctcta aaattcaaaa
    15721 acaggtccat agagacttag tacgtgtttg acatgatcgt aatggaattt atcatagttt
    15781 cgccaagcag tgcgtgcttg atcgtttagt tttaggctac ccagtccaat cagaagactg
    15841 gtaggttggt aaaatttctc aagatcaatt aagatactgt tgttcaactg ttccgttttt
    15901 ttgagctctt gcatagtagt gtttagcagc tcttgtagtc gaatatcatc tgccgtaccc
    15961 tgtttacagt tttggtagct tttatttaac ttggatagga gttgaatgag tttcttgtct
    16021 tccatgtgag catcctcctt gatctgatgt actctttccc tatagtatag cactaaaaaa
    16081 taaaactatc atagtaaata tgttaaaatt ttgaatttta attacaaagt ttggtgtgct
    16141 gatttgtagc cttttcatgg tataatcaag agagtaaatc tttatggagg aagtatgaaa
    16201 ttaaatattc aagaaattcg taagcagtct gaaggtttga actttgaaca aacgttagat
    16261 ttagttgatg acctgcgtgc acgtaatcaa gaaattttag atgtaaaaga tatccttgca
    16321 gttgggaaag tacaatatga agaccgtatg tatttcttag attatcaact atcttatacc
    16381 attgttcttg cttcgagtcg cagtatggag ccagttgagt tagttgaatc ttatccagtc
    16441 acggaagttt tcatggaagg cgcaactaac cagctagatc aagaagtttt agatgatgac
    16501 ttggtcttgc ccatcgaaaa tggggagctt gaccttgctg agagtgtatc agacaatatc
    16561 ctgctaaaca ttcctatcaa ggtcttgacg gctgaagaag aagctggtca aggatttatc
    16621 tcaggaaatg actggcaaat catgacagag gaagaatacc aagctcaaaa agcagtaaag
    16681 aaagaagaaa acagtccttt tgctggctta caaggactat ttgacggaga tgaataatgg
    16741 tcttgtcaaa aaaacgagca cgaaaggtgc tagaagaaat cattgccctc ttcccagatg
    16801 ccaagcctag tcttgatttt accaatcatt ttgaactcct ggttgcggtc atgttatcag
    16861 cccagacgac agatgcagcg gtaaataagg ccacaccagg tctctttgtt gcctttccaa
    16921 caccccaagc tatgtctgta gcgacagaga gtgagattgc ttcacatatt tctcgcttgg
    16981 gattgtatcg gaataaagct aaattcctta aaaaatgtgc ccaacagtta ctagacgatt
    17041 ttgatggtca agtccctcag acacgtgaag aattggagag tttggcaggt gttggtcgca
    17101 agacagccaa tgttgtcatg agtgtaggat ttggaattcc agcctttgca gtggatactc
    17161 atgtggagcg tatttgcaaa caccacgata ttgtcaaaaa atcagcgacg ccacttgagg
    17221 tggaaaagcg ggtcatggat atcttgccgc ctgagcagtg gttagctgcc catcaggcca
    17281 tgatttattt tggaagagcc atttgccatc caaaaaatcc agagtgtgac cagtacccac
    17341 aattatatga ttttagcaat ttgtaagatg ctacattgaa actttttgct tgattttaag
    17401 catgctttgt gctatagtaa atgataacta aatattcctt taaacctgtc ccgtgaggca
    17461 ggcaaggagc gcgataaagt agaagggtga agtctatact gtgtgcagta gggctcgctt
    17521 ggctataaat ttcaagtctc cttgtttaag gagacttttc tttttggagg tttgtcatga
    17581 aaacaaaaga agttgtagac gaattgaccg tcaaacgagc gattacgcgt attacttatg
    17641 agattatcga acgcaacaaa gatttgaata agatcgtctt ggctggtatt aaaactcgtg
    17701 gtgtctttat tgcccaccga atccaagaac gtttgaagca gttagaaaat ctttcagttc
    17761 ctgttgtgga attggatact aaacctttcc gtgatgatgt taaaagtgga gaagatactt
    17821 ctttggtttc tgtcgatgtg acagaccgcg aagttatctt ggtggatgat gtgctctata
    17881 caggtcgtac catccgtgct gctattgata atattgtcgg tcatggtcgt cctgcgcgtg
    17941 tgagtttagc agttctagtc gatcgtggac atagagaatt gccaatccgt ccagattacg
    18001 ttggaaaaaa tatcccaacc agtcgttctg aagaaatcat cgtagagatg acagaacttg
    18061 atgaccaaga cagagttctg attactgaag aagcttagaa agttaaagga gtagccatgt
    18121 cagaaaatca acaagcattg aaccatgtgg tgtccatgga agacctcact gtcgatcaag
    18181 taatgaaatt gatcaagcga ggaattgagt ttaaaaatgg agcccagctt ccctatgaag
    18241 accatccgat tgtttccaat ctcttctttg aggattctac acggacacat aagtcctttg
    18301 aagtcgcaga gattaaactt ggattggaac gacttgactt tgatgtgaag actagctcgg
    18361 ttaataaggg tgagacactt tatgacacca ttttgactct gtctgcttta ggagtggatg
    18421 tctgtgtgat tcgccatcca gaggtcgact actatagaga attgattgct agtccaacga
    18481 ttacgacttc catcatcaat ggtggagatg gttcgggcca acaccctagc cagagcttgc
    18541 ttgatttgat gaccatttat gaggaatttg gccactttga gggtcttaaa gttgctattg
    18601 caggtgactt ggaccactca cgcgttgcca aatccaatat gcagattttg aaacgcttgg
    18661 gagctgaact ctttttcgct ggacctgagg aatggagaag tcaagagttt gcagactatg
    18721 gacagtttgt aaccattgat gaaatcattg atcaggttga tgtcatgatg tttctccgtg
    18781 tgcaacacga acgccatgat agtggagctg tattttcaaa agaagactac catgcccaac
    18841 atggcttgac tcaagaacgt tacgatcgtt tgaaagaaac agcaatcctc atgcacccag
    18901 ctccaatcaa tcgtgatgta gaaatagcag accacttggt tgaagcacca aaatcacgga
    18961 ttgtccaaca aatgaccaat ggtgtctttg ttcgaatggc aatcttagaa tccgtactag
    19021 cgagtagaaa cgccaactaa aacacaagac gttaaaagac gccagtgagc gtccacgaga
    19081 ggtgaaaata tgacaaaaag aattctagta ttagaagatg gcacagtttt tgaaggcaag
    19141 gccttcggag cagatattga tgtaacaggc gaaatcgtct ttaatacagg gatgaccggc
    19201 taccaagaat ccattacaga ccagtcttat aatggacaaa tcttgacctt tacttatcct
    19261 ttggtaggaa attatggtat taatcgtgat gattatgaat ccattattcc aacttgtaag
    19321 ggagtcgttg tttttgaaga agcgcgtaga gctagcaact ggcgcaacca aatgaccttg
    19381 gatgaatttt tgaaagccaa gaaaattcca gggatttcag gaattgatac gcgtgctctt
    19441 accaagatta tccgtaagca tggtactatg cgtgcaacct tgacccatgt tggggacagt
    19501 atggaccatg tgacggacca gctccaagca acagttttac cgacagacaa tatcaaacag
    19561 gtttctacta aaacgtctta tccagctcca ggagttggtt tgagcgtggt gctagtggac
    19621 tttggtctca agcactcaat cctacgtgaa ctttctaaac gcaactgtaa cgtgacagtt
    19681 gttccttatt cgacaacggc tgaagaaatt ctccatctca atcctgacgg agttatgttg
    19741 tcaaatggtc caggtaaccc agaagacgtt ccacaagcac tcgacatgat tcgcggtgta
    19801 caaggaaaaa ttccaatctt tggtatttgt atgggacacc aactctttgc aatggcaaac
    19861 ggggctaaga cctataagat gaagtttggc caccgtggat tcaaccatgc ggtacgtgaa
    19921 atcgcaacag gacgagtaga cttcaccagc cagaaccatg gttatgcagt cagccgcgag
    19981 gatttgccag agcacttgat tattacccac gaagaaatca atgacaagtc agtggaaggt
    20041 gtgcgccaca gataccaacc tgctttctct gttcaatacc acccagatgc agctcctggg
    20101 ccacacgacg ctagctacct atttgacgag tttatcgaga tgatggaagt ttttaaacaa
    20161 tcaaactaag aacgagtaaa agctcgtcgg agaatttatg taactgaaca cggacggaaa
    20221 gctcagaatg tagagaaacc aacttggatt gtcaatcctt ccttgatttc ctaaaattca
    20281 atcgctttct attcgtcctt tgtatcttat ttaatgtcgc cctgagaggc gacgaataga
    20341 aaggagaagg gtgctccgta tttgctgaac tgaatacggg ctacggacgg tgctaaaaag
    20401 atagttattc ctagaactga cagttcttcg tcataactcc tattttagct ttgtccgctt
    20461 gacaccctta atatcttata tatgcctaaa cgtactgata ttcaaaaaat tatggtgatt
    20521 ggttctggtc cgattattat tggtcaggct gctgagtttg actacgctgg gactcaggct
    20581 tgcttgtcgt tgaaagagga aggttatgag gttgttttgg ttaactcaaa tcctgcaacc
    20641 atcatgacgg acaaggaaat tgctgacaag gtttacattg aaccgattac acttgagttt
    20701 gtgacacgta ttcttcgtaa ggaaggtcca gatgccttgc taccaacact cggtggtcag
    20761 acaggtctca acatggccat ggaattatct aaaaatggta tcctagacga gcttggcgtt
    20821 gaacttctgg gtaccaaatt atctgccatt gaccaagcgg aggaccgtga cctctttaaa
    20881 caattgatgg aagagcttga acaacccatt ccagaatctg aaattgttaa cacagtagaa
    20941 gaagcagttg cctttgcagc gacaattggc tacccagtca tcgttcgtcc agcctttacc
    21001 cttggtggta ctggtggtgg tatgtgtgcc aacgagaaag aattgcgtga aatcactgaa
    21061 aatggtttga aattgtcacc tgttacccaa tgtttgattg agcgttcgat tgccggtttc
    21121 aaggaaattg aatacgaagt gatgcgtgac tcagctgaca atgccttggt tgtttgtaac
    21181 atggaaaact ttgacccagt tgggattcac acaggggatt ccattgtatt tgcccctgcg
    21241 caaaccatgt cagactatga aaaccaaatg cttcgtgatg cgagcttgag cattattcgt
    21301 gccctcaaga ttgaaggtgg atgtaatgtt cagctagctc ttgatcctaa cagcttcaag
    21361 tattatgtta tcgaagtaaa ccctcgtgta tcacgttcgt cagcccttgc ttctaaagcg
    21421 acaggatatc cgattgctaa gttggctgcc aagattgcag taggtttgac cttggatgag
    21481 gttataaacc cagttacagg ttcaacctat gccatgtttg aaccagccct tgactacgta
    21541 gttgctaaga ttccacgttt cccatttgac aagtttgaaa agggtgaacg ccgtctcggt
    21601 acacaaatga aggcgactgg agaagtcatg gcaatcggtc gtaacatcga ggaatctctt
    21661 ctcaaggcct gccgctccct tgaaattggg gtgcaccaca atgaaatacc tgaacttgca
    21721 gcagtttctg atgatgcctt gattgaaaag gttgtcaaag cccaagatga ccgtctcttc
    21781 tacgtatcag aagccattcg tcgtggctac acacctgaag aaattgcaga gcttacaaaa
    21841 attgatatct tctatcttga taaactcttg catatctttg aaattgagca agaattgggt
    21901 gctcatccac aagatttaga agttttgaaa acagccaaac ttaatggttt ttcagaccgt
    21961 aagattgctg aactctgggg aacgactgat gataaagttc gccaacttcg cttggaaaac
    22021 aagattgttc cagtttataa gatggtagac acttgtgcgg cagagttcga ctccgaaacg
    22081 ccatatttct attcaaccta tggttgggaa aatgaatcta tcagatctga taaagaatct
    22141 gtacttgtcc taggttcagg tccaatccgt atcggtcaag gggttgagtt tgactacgca
    22201 accgttcact ctgttaaggc tatccaggca gctggttatg aagctatcat catgaactca
    22261 aacccagaga ccgtttcaac agacttctct gtatcagata agctttactt tgagccattg
    22321 acattcgaag atgttatgaa cgtcattgac ttggaacaac caaagggagt tatcgttcag
    22381 ttcggtggtc aaacagccat caaccttgcg gagccattgg caaaagcagg tgtgaccatc
    22441 cttggtacac aggttgctga cctagatcgt gccgaagacc gtgacctctt cgagcaagct
    22501 ctcaaagaat tggatattcc acagccacca ggacaaacgg ctaccaatga agaagaagca
    22561 gctcttgcag ctcgcaagat tggcttccca gttcttgtcc gcccatctta tgtacttggt
    22621 ggacgtgcca tggaaatcgt tgaaaacgaa gaagaccttc gttcttacat gcgaactgct
    22681 gttaaggcta gtccagacca cccagttctt gtcgactctt atatcgttgg gcaagagtgc
    22741 gaagttgatg ccatttcaga tggtaaaaat gtactcattc ctggtatcat ggagcatatc
    22801 gaacgtgctg gtgtccactc aggtgactca atggctgttt acccaccaca aaccttgtcg
    22861 caaaaggttc aggagaccat cgcagactac accaaacgct tagcaatcgg tcttcactgc
    22921 cttggaatga tgaacatcca gtttgttatc aaggatgaaa aagtctacgt tattgaggtc
    22981 aatccacgtg ccagccgtac tgttccattc ctatctaagg taaccaatat tcctatggct
    23041 caagtagcga ccaaactcat tcttggtcaa agtttatcag aacttggcta ccaaaatgga
    23101 ctttaccctg aaagcacccg tgttcatatc aaggcacctg tcttctcctt taccaaacta
    23161 gctaaggtag acagcttgct cggtcctgaa atgaagtcaa caggtgaagt tatgggttct
    23221 gatgctactt tggaaaaagc tctctataaa gcctttgaag cttcttatct acacttgcca
    23281 acttttggta atgtcgtctt taccatcgct gatgatgcca aagaagaagc cttgaacttg
    23341 gctcgtcgtt tccaaaacat tggttatgga atccttgcga cagaagggac agcagccttc
    23401 tttgctagtc atggcttgca agcccaacct gttggtaaga ttggtgatga cgataaggat
    23461 atcccaagtt ttgtacgcaa aggaagaatt caagctatca ttaacacagt aggaacaaaa
    23521 cgaactgctg acgaagatgg tgagcaaatt cgtcgttcag ccattgaaca cggggtgccc
    23581 ctcttcacag cgctagatac agctaatgcc atgcttaagg tacttgaaag tcgtagcttt
    23641 gttacagaag cgatttaaat agaaaaataa gatatagcag actgaattta gaacagtaca
    23701 caggaatact aaaatatttc tataaattaa tttgaatttt ctaattgatt tgttcgcatc
    23761 ttatttcaat ctactataga aaaaagtctt taaaattata aaacgcatca tatcaaggtt
    23821 tttcaaaaac cttgatatga tgcgttttat tgtgggaata tgtatttcat tttctactaa
    23881 aattatgttt ttgaataacc tctatcttag tagtttgtat aatccccctc aatcagtttt
    23941 tgcgataagc tttaatgcta tgactatacc actcttgcat ttcttttgat ggtggtgtca
    24001 tataatcgcc atacatctgg gttaaaaatt ggtcatattt tttgggaaca ggcaacatac
    24061 ggccctcaaa ctcagttaaa atcagttctt taaaggtatc aactgggaag atttctttca
    24121 tcccttcctt accgatccca actcctcctt catattgagg agtgttggtt acagcatttt
    24181 tgactagttg atcaattttc ttgtaaaagt agcgaggatt gacaaatcgg agagcgtacc
    24241 agctacataa tctaagaaaa tcttttagtt tgctatcacc gtgaactgct cgtgattttt
    24301 tgatataagc tagttgacga agagccacat acttatagct cttgtcgaca atgctcaagt
    24361 ctgtaaatcg atcaattggg aagacatcga tgaaaaggct ggtatcatga cgcttgtact
    24421 taacatggtc ttctataaca gtagaagtgt ccaaaatcga tgcgaaatta tggaagtacc
    24481 aagaagatgt atcgtaggaa agaaccttgt agtgagggtg attttcttct tcaataatct
    24541 tcagtaaacg ctcataatcc tcacgataaa gggaaatatc aatatcatca tcccaaggaa
    24601 tcataccttt gtggcggatg gctccaagca tggttccata actgagaaaa taaggaatat
    24661 catgtttctt acaagtctca tcaatatagt ccagcagggc tagttgaatt tctttaattt
    24721 cttttttttc taaatattgc atcctaatcc tccaatttat aagcgtgaaa ttcatgactg
    24781 tagaagcgtt tttcttctgg tggtagggtc atataatctc cataaaattg tgtcaaaata
    24841 gtatcaaatt tttcaggtgc aggaaggctt aaattctcaa agggtaaatc gattgtttta
    24901 tcaaaggtac cacttgggaa gacttccttt tccttaaatt ttgaagggat aaaagccata
    24961 tattgcccat tttcacgact atatttttga atttctttct cgattttatt tgcaaaataa
    25021 cgaggagaaa ccggtcgaag gagtaaccag aaggctgttc gtatccaatc ttttaaaagg
    25081 ctatccttat agacaatatt tttatgttta ctgaaagaca gcagtttgaa gctttccagt
    25141 ttataacaag tatcaatgac cttaggatca tcaaagcgat ctatagggaa aatatcgata
    25201 aagataccag actcataggt ttttgtattt cgagtatcaa taattttagt cgtactgtcg
    25261 gttatcttga taaagttgtt aaagtagttc ttatcagttt ctaaggatag gagcttatac
    25321 ttgctttttt ccttttgaaa aatgttaata aatcgttggt agtcttctct aggcatggac
    25381 agatcaatat cgtcgtccca agggataaag ccctcatgtc gaaccgcccc aatcagagta
    25441 ccgtagttaa taatatagtt gatattgtgc tttttacaga gagtatcaat ataatccaaa
    25501 atttctaatt caatttgttt ggcatcttca acggttagtt gtttcatttt aaactcctat
    25561 gattttttaa atttattttt taaggctagg acatggttta aaaattcata gaaaatgcta
    25621 tcttttgtga agacaagtag actaatataa gagatagctg atagcaagac aatcaaacca
    25681 gtattaatca aaaatggcaa attaatgacc atatctacag gatacacgaa attaatcagg
    25741 aaataaattg ctacaaagga aagtgaaaag agagagtatc gaacagtata gctaaagata
    25801 tgtcccaagt ggatgagttg ttttctatgg atgaaaatga tatagaaaac aagtagagaa
    25861 gtctctgata gcatagttgt cagtaagtag tattcaggag ccacgatatg gttgaaaaaa
    25921 aggagactat tcaagcccaa attgagtagc ccagcaaaga ctgtatagac tgtgatacgt
    25981 ttttcatagc cattggtaaa gagaatttgg gaaccaagaa tggtatctaa ggccaggata
    26041 atcgtacgaa aagcgaagag agaggtcaag atgccgcctc cgatatattt ttcactaccg
    26101 taaagtagga tggcatttgg tcctaaaacc atgagtccaa aactcagtgg aatgataaag
    26161 aagttaaaga ttcgactacc tctattaacc agagaaacat aggcttcttt gtctcctttc
    26221 cccagatagt aactgagacg aggcacactc actccaattg cacctgttac aaccccagct
    26281 ataacggtca caattcgctg agctatggta tagtaactaa cgttgacatc aatccctgtt
    26341 ttaacgagga agaggcgatc taaaaaagtg aagagcatat tggcattggc aaagactaac
    26401 atggctgtca gagggagaaa gagtggttta aaatcactta ggtgaatttt aacaagtttg
    26461 atgtctcttt taatccaaaa ataactaatc aggtagttaa tcagcgtcga taaactcatc
    26521 acaagtgtat agacaacaat atcgtgttca tttttaacaa ataagaaaat agagaccagc
    26581 atcaggatac ggatgaaggc agttttgtaa aagagaaaac tgtaattttc cagagcttca
    26641 ttgacccatt cgattgaaaa aatctgggca atgagttgaa tccccataac aaggtagacc
    26701 tttttgacga ttggattatc agtaaagaag agaggatagg ctaggatata gacagcagtg
    26761 gtcaaaatcg tacaagcgat gcacaaataa aaaagactag aaaaggttct gttaagatct
    26821 tttttgttat ccttgacatt actgatagcc cttaaaccgt agttatagac accataagtt
    26881 gcaaagggca agaaaaatga caaaatagtg tcgactgagt tgaagtaacc atagtcagtt
    26941 cggtccaaga cacgcgcgac ataggttcca gttaggatgg gaaaaataat attcaagaca
    27001 cgaattccca tgtaagatag agcatttaat tttatacttt tcattcaatt tacctcgttt
    27061 ttcattatat cataaagtta gctaataaga aatgaagggc agtaagtcaa gtaatcactt
    27121 tgaagtttca aatcttaagt tttaagtttt ctttaaggaa agtatattat tctgaaggac
    27181 tctaaaattt cgcagccatt tattagtaat tgctacagaa ttcctagtca ttactagaaa
    27241 tggactagtt tctttgaata atagaactgc ataattctcc tattctagaa ggggaggacc
    27301 agtatttctt ttatgatagg actagattgt ggtataatag agagaataag tttttttagt
    27361 aagacaaagg agaaaataga tgatttatgc aggaattctt gccggtggaa ctggcacacg
    27421 catggggatc agtaacttgc caaaacaatt tttagagcta ggtgatcgac ctattttgat
    27481 tcatacaatt gaaaaatttg tcttggagcc aagtattgaa aaaattgtag ttggtgttca
    27541 tggagactgg gtttctcatg cagaagatct tgtagataaa tatcttcctc tttataagga
    27601 acgtatcatc attacaaagg gtggtgctga ccgcaataca agtattaaga acatcattga
    27661 agccattgat gcttatcgtc cgcttactcc agaggatatc gttgttaccc acgattctgt
    27721 tcgtccattt attacacttc gcatgattca ggacaatatc caacttgccc aaaatcatga
    27781 cgcagtggac acagtggtag aagcggttga tactatcgtt gaaagtacca atggtcaatt
    27841 tattacagat attccaaatc gtgctcacct ttatcaagga caaacacctc aaacattccg
    27901 ttgcaaggac ttcatggacc tttatggatc tctttctgat gaagagaagg aaatcttgac
    27961 agatgcatgt aaaatctttg tgatcaaagg aaaagatgtg gctttggcca aaggtgaata
    28021 ctcaaatctg aagattacaa ccgtaacaga tttgaagatt gcaaaaagta tgattgagaa
    28081 agactagtaa aatgattaat caaatttatc aactaactaa gcctaagttt atcaatgtca
    28141 aatatcagga agaggctatt gaccaagaga atcatatcct tatccgtccc aactacatgg
    28201 ctgtctgtca tgcggatcag cgttactatc agggaaaacg tgatcccaag attttgaata
    28261 aaaagcttcc aatggcaatg attcacgagt catgtggaac cgtcatttct gacccgaccg
    28321 gaacctacga ggttggtcaa aaagttgtca tgattcccaa tcagtctcct atgcagagtg
    28381 atgaagaatt ctatgaaaac tacatgacag ggacccattt cttgtctagt ggatttgatg
    28441 gctttatgag agagtttgtt tctctcccta aagatcgtgt ggtggcttat gatgctattg
    28501 aagatacggt tgcagccatt acagagtttg tcagtgtggg catgcacgct atgaatcgtc
    28561 tattgactct tgctcatagc aagcgggagc ggatcgccgt tattggagat ggaagtttag
    28621 cttttgtggt tgccaatatt atcaactata ctttgccaga agcagagatt gtggttattg
    28681 gtcgtcattg ggaaaagttg gaactcttct catttgccaa agaatgctat attacggata
    28741 atattcctga agatttggcc tttgaccatg cttttgaatg ttgtggtggt gatggtactg
    28801 gaccagctat taatgacttg attcgctaca ttcgtcctca gggaacgatt ctcatgatgg
    28861 gagttagcga atataaagtc aatctcaata ctcgcgatgc cttagaaaag ggcttgattt
    28921 tggttgggtc atctcgttct ggtcgcattg attttgaaaa tgctatccaa atgatggaag
    28981 tcaagaaatt tgccaatcgt cttaaaaata tcctttatct agaagaacct gtaagagaaa
    29041 ttaaagatat tcatcgtgtc tttgcaaccg atttaaacac agcctttaaa acagtgttta
    29101 agtgggaagt ataagtactg gaggttaatt gtggagaaaa tcattaaaga aaaaatttct
    29161 tccttactta gtcaagaaga ggaagtcctc agtgttgaac aactgggtgg aatgaccaat
    29221 caaaactatt tggccaaaac aacaaataag caatacattg ttaaattctt tggtaaaggg
    29281 acagaaaagc ttatcaatcg acaagatgaa aagtacaatc ttgaactact aaaggattta
    29341 ggcttagatg taaaaaatta tctttttgat attgaagctg gtatcaaagt aaatgagtat
    29401 atcgaatctg cgattacgct tgattcaacg tcaatcaaga ccaagttcga caaaattact
    29461 ccaatattac aaactattca tacgtctgct aaggaattaa gaggagaatt tgctcctttt
    29521 gaagaaatca aaaaatacga atccttgatt gaagaacaaa ttccttatgc caactatgaa
    29581 tctgttagaa atgcagtctt ctccttagag aaaagactgg ctgacttagg tgttgacaga
    29641 aaatcttgtc atatcgattt ggtgcctgaa aactttatcg aatcacctca aggacgactt
    29701 tatttgattg actgggaata ttcatcaatg aatgatccaa tgtgggattt ggctgccctc
    29761 tttttagagt ctgaattcac ttcccaagag gaagaaactt tcttatctca ctatgagagt
    29821 gaccaaacac cggtttctca tgaaaagatt gctatttata aaattttaca agatactatt
    29881 tggagtctat ggactgtcta taaggaagag caaggtgaag attttggtga ctatggtgtg
    29941 aatcgttacc aaagagctat taaaggtttg gcttcttatg gaggttcaga tgaaaagtaa
    30001 aaacggagtt ccttttggcc ttctctcagg tattttctgg ggcttgggtc taacggttag
    30061 tgcttatatc ttttcgattt ttacagattt gtcacccttt gtggtggctg caactcatga
    30121 ttttttgagc atctttatct tactagcttt tctcttggta aaagaaggga aagttcgcct
    30181 ctcaattttc ttaaatattc gcaatgtcag tgttatcatc ggagccttgc tagcaggccc
    30241 tatcggtatg caggccaatc tttatgcagt taagtatatc ggaagttctt tagcttcatc
    30301 tgtatcggct atttaccctg cgatttcagt tctattggct ttcttctttt tgaagcacaa
    30361 gatttcgaaa aatactgtat ttgggattgt cttgattatt ggagggatta ttgctcagac
    30421 ctataaggtt gaacaggtta attctttcta cattgggatt ctttgtgctt tggtttgtgc
    30481 tattgcatgg ggaagtgaga gtgttcttag ctcttttgcc atggaaagtg aattgagtga
    30541 aatcgaagcc ctcttaatcc gtcaagtaac ttcgttcttg tcctatcttg tgattgtgct
    30601 cttctctcat cagtcattta ctgcagtagc caatggacaa ttgctaggtc tcatgattgt
    30661 ttttgcagcc tttgatatga tttcctactt ggcttattat atcgctatca atcgcttgca
    30721 accagccaag gctacaggct tgaacgtgag ctatgtagta tggactgtct tgttcgcagc
    30781 tcttttcttg ggaacatcat tagatatgct gaccattatg acgtcacttg tcgtcattgc
    30841 tggagtttat attattatta aagaataaag gagattcgtg tgaaagccat tatcttagca
    30901 gcgggattgg gaactcgctt gcgtcctatg actgaaaata cccctaaagc cttggttcag
    30961 gttaatcaaa aacctttgat tgaataccaa attgagtttc tcaaagaaaa aggaatcaat
    31021 gacatcatca tcatcgttgg ttatcttaaa gaacaattcg attatttaaa agagaaatac
    31081 ggtgttcgtc tcgttttcaa tgataaatac gctgactaca ataactttta ctctctctat
    31141 cttgtaaaag aagaattagc caatagttat gttatcgatg ccgataacta tctctttaaa
    31201 aatatgttcc gcaatgattt gacacgttct acttatttta gtgtctatcg tgaagattgt
    31261 accaacgaat ggttcttggt ctatggagat gactacaagg ttcaagacat tattgttgat
    31321 agcaaggcag gtcgcatcct tagtggtgta tccttctggg atgctccaac tgcagaaaag
    31381 attgtcagtt ttatcgataa ggcttatgca agtggcgaat ttgttgatct ctactgggac
    31441 aatatggtta aggataatat caaagagcta gatgtctatg ttgaagaatt agaaggcaat
    31501 agcatttatg agatcgatag tgtccaagac tatcgtaaat tagaagaaat tcttaaaaac
    31561 gaaaattaaa gattccaaca tctgacaaaa tagtcggatg tttttttgat tttttacgaa
    31621 cttttacgaa tagatagatg agtagaaaaa gaaatggagt tatttatgaa aatcacaaac
    31681 tatgaaatct ataagttaaa aaaatcaggt ttgaccaatc aacagatttt gaaagtgcta
    31741 gaatacggtg aaaatgttga tcaggagctt ttgttgggtg atattgcaga tatatcaggt
    31801 tgccgaaatc cagctgtttt tatggagcgt tattttcaga tagacgatgc gcatttgtcg
    31861 aaagagtttc aaaaatttcc atctttctct attttagatg actgttatcc ttgggatttg
    31921 agtgaaatat atgatgcgcc tgtactttta ttttacaagg gaaatcttga cctcctgaaa
    31981 ttcccgaagg tagcggtcgt gggcagtcgt gcttgtagca aacagggagc taagtcagtt
    32041 gaaaaagtca ttcaaggctt ggaaaatgaa ctggttattg tcagtggtct ggccaagggc
    32101 attgacacag cagctcatat ggcagctctt cagaatggcg gaaaaaccat tgcagtgatt
    32161 ggaacaggac tggatgtgtt ttatcctaaa gccaataaac gcttgcaaga ctacatcggc
    32221 aatgatcatc tggttctaag tgaatatgga cctggcgaac aacctctgaa atttcatttt
    32281 cctgcccgta atcgcatcat tgctggactt tgtcgtggtg tgattgtagc agaggctaag
    32341 atgcgttcag gtagtctcat tacgtgtgag cgagcaatgg aagaaggacg cgatgtcttt
    32401 gctattcctg gtagcatttt agatggacta tcagacggtt gccatcattt gattcaagaa
    32461 ggagcaaaat tggtcaccag tgggcaagat gttcttgcgg aatttgaatt ttaaaaatga
    32521 cctaagctag aattctaaga aaaaatcaat tttaagagaa aatgaaccca acatttccat
    32581 aataaaacgc atattagcaa gtttttaaca cttgataata tgcgtttttt ctaagtggat
    32641 tagtagagta gaggattttt ctcatataat actcttcgaa aatctcttca aactacgtca
    32701 gcttccatct gcaacctcaa aacagtattt tgagctgact tcgtcagtct tatctacaac
    32761 ctcaaagcag tgctttgagc aacctgtggc tagcttccta gtttgcgctt tgattttcat
    32821 tgagtataag ggaaagtata gtgaattgaa ataagatgtg aacaactcta tcaggaaagt
    32881 caaattaatt tatagaaata ttttagcagc caaggtgcac tgttatagat tcaatacact
    32941 ataatttagt gtaattgaga aaggagaaat gattgtgatt gatgttggct aggttatgtt
    33001 caatgattcc taccgtctca aatcttgtca gtaaggaaaa ataaattctt caaaagtaga
    33061 gattacaagg cttgtttaag aaagaattca aagaccttga caaataaaaa taaaatggtt
    33121 attataagaa atggtctaaa atagatgatg atacttttcg aaaatctttt tacgtcagct
    33181 cagctttgcc ttgctgtgtt ttgagcaagc tacggttagc ttccgagttt gattttcatt
    33241 tactagaaat gaaactgatg agagatatca gtagacattt gagtcaggat attatggaaa
    33301 atgataaaaa gagctcgtga gattggcata tcagactact aaagtattga gtttgttagg
    33361 attttagcga ctagttagct gggaaaggaa gatatttgtg acaaataata aactgtattc
    33421 gttgatagaa tttagaaata agatatatga agaattagaa ctttccagaa gtgatttagc
    33481 gattttacta tgtgccatgc ttatcgcctc tatcggatta aatatggatt cgactcccgt
    33541 gattattgga gccatgttaa tctctccttt gatgacacct attctgggag tggggctctc
    33601 tctagctata tttgatttta aattgttaag aaaatctttt aaaatattag ctattcaaat
    33661 tcttgccagt ttaatagctt caacacttta tttttatctt tctcccattt cgtatgctag
    33721 ttcggaaatt gttgctagaa cctctccgac tatttgggat gttctcattg cttttgtagg
    33781 agggatagca ggtattattg gtgctaggaa aaaagagacc aataatattg ttcctggtgt
    33841 tgctattgca accgccttga tgcctcctct ttgtacagta ggttatgcta ttgcttctgc
    33901 taatctaaaa tttatcatag gctcctctta cctattcctc atcaattgta gctttattgt
    33961 cattgcgact tatataggtg ttaggttgat gatggttaag aaacattatt ttaaagataa
    34021 tgaagaagac tctaaaatgc gtaggatttt gcttctagtt gctgttttgc tgatgattcc
    34081 gagtttcatc tctgcaacga ctttagtgag agaaacgttg aaaaaagagt cccttaagaa
    34141 atttatatca gagcagtttc aggggtataa tattttgaaa aaaacctatt ctaaaaagac
    34201 tcatacccta aagctaacca tttcaggaaa ttatttgaca gaagaagaac tcgatatgat
    34261 ttcaagtaag agaggtgact atggtttaag tgatgtttct gttcaagttt cacaattgtc
    34321 tgattcagaa caacttagta aggaagagct ggtggagcat ttcttccagt atatcaagga
    34381 taaggaagca aaagaaaagg agaaagccaa taaatttgat acagagtctg aggagcaata
    34441 atttcttgag aatagctggt ttctctcgtg agtcttctat gtatatcaaa ggaagactga
    34501 ggttttaagt ataaaacttt tcttctatta tagtagctaa gtcttgacag ggttcaaaaa
    34561 atggtttaca ctttataaag tttattactt tgaaaaggtg tgatactgtg gctacggcaa
    34621 caaaaaagaa aaaatcaaca gttaaaaaaa atctagtcat cgtggagtcg cctgctaagg
    34681 ccaagacgat tgaaaaatat ctaggcagaa actacaaggt tttagccagt gtcgggcata
    34741 tccgtgattt gaagaaatcc agtatgtccg tcgatattga aaataattat gaaccgcaat
    34801 atatcaatat ccgaggaaaa ggccctctta tcaatgactt gaaaaaagaa gctaaaaaag
    34861 ctaataaagt ttttctcgcg agtgacccgg accgtgaagg agaagcgatt tcttggcatt
    34921 tggcccatat tctcaacttg gatgaaaatg atgccaaccg tgtggtcttc aatgaaatca
    34981 ccaaggatgc agtcaaaaat gcttttaaag aacctcgtaa gatcgatatg gacttggtcg
    35041 atgcccaaca agctcgtcgg atcttggatc gcttggtagg gtattcgatt tcgcctattt
    35101 tgtggaagaa ggtcaagaag ggcttgtcag caggtcgcgt tcagtccatt gcccttaaac
    35161 tcatcattga ccgtgaaaat gaaatcaatg ccttccagcc agaagaatac tggacagttg
    35221 atgctgtctt taaaaaggga accaaacaat ttcatgcttc cttctatgga gtagatggta
    35281 aaaagatgaa actgaccagc aataacgaag tcaaggaagt cttgtctcgt ctgacgagta
    35341 aagacttttc agtagatcag gtggataaga aagagcgtaa gcgcaatgct cctttaccct
    35401 ataccacttc atctatgcag atggatgctg ccaataaaat caatttccgt actcgaaaaa
    35461 ccatgatggt tgcccaacag ctctatgaag gaattaatat cggttctggt gttcaaggtt
    35521 tgattaccta tatgcgtacc gattcgactc gtatcagtcc tgtagcgcaa aatgaggcgg
    35581 caagcttcat tacggatcgt tttggtagca agtattctaa gcacggtagc aaggtcaaaa
    35641 acgcatcagg tgctcaggat gcccatgagg ctattcgtcc gtcgagtgtc tttaatacac
    35701 cagaaagcat cgctaagtat ctggacaagg atcagctcaa gctatatacc cttatctgga
    35761 atcgttttgt ggctagccag atgacagcgg ccgtttttga taccatggct gttaaattgt
    35821 ctcaaaatgg agttcaattt gctgccaatg gtagtcaggt taagtttgat ggttatcttg
    35881 ccatttataa tgattctgac aagaataaaa tgctaccaga tatggctgtt ggagatgtgg
    35941 tcaaacaggt taatagcaaa ccagagcaac atttcaccca accgcctgcc cgttattctg
    36001 aagcaacact gattaaaacc ttagaggaaa atggggttgg acgtccatca acctatgcgc
    36061 caaccattga aaccattcag aaacgttatt atgttcgcct ggcagccaaa cgttttgaac
    36121 cgacagagtt gggagaaatt gtcaataagc tcatcgttga atatttccca gatatcgtaa
    36181 acgtgacctt cacagctgaa atggaaggta aactggatga tgtcgaagtt ggaaaagagc
    36241 agtggcgacg ggtcattgat gccttttaca aaccattctc taaagaagtt gccaaggctg
    36301 aagaagaaat ggaaaaaatc cagattaagg atgaaccagc tggatttgac tgtgaagtgt
    36361 gtggcagtcc aatggtcatt aaacttggtc gttttggtaa attctacgct tgtagcaatt
    36421 tcccagattg ccgtcatacc caagcaatcg tgaaagagat tggtgttgag tgtccaagct
    36481 gtcatcaggg acaaattatt gagcgaaaaa ccaagcgtaa tcgcctcttc tatggttgca
    36541 atcgctatcc agaatgtgaa tttacctctt gggacaagcc tgttggtcgt gactgtccaa
    36601 aatgtggcaa cttcctcatg gagaaaaaag tccgtggtgg tggcaagcag gttgtttgta
    36661 gcaaaggcga ctacgaggaa gaaaagatta aataagagga ggggcccgaa agtaaatttc
    36721 aggctccttt tggttagaac ttgacaaaat acatcatttt atgcgaaact agaagaagat
    36781 tattttaact aggagaagtt atgcgtctta tctatctgat aattggtttt ttatcactgg
    36841 ccttggctat tgttggggtt gttttaccct tgttgccgac aacgcctttc cttttgttgt
    36901 ctattgcttg tttctccaga agttccaagc gtttcgaaga ctggctttat catactaagc
    36961 tctatcaaac atatgtagct gattttcgcg agactaagtc tattacgcgt gaacgaaaga
    37021 aaaaaatcat cgtctctatc tacgtcttga tgggaatttc tatttatttt gcacctcttt
    37081 taccagtcaa aatcggtctg ggtgctttga ccatctttat cacttattat cttttcaagg
    37141 tcattccaga caaagaatag ttaaaacagt agttatttgc cttgataaaa ttgaaagcat
    37201 attcataata atatgatata ataaatttga agtaatattc aaggagaatc aaatgattta
    37261 cgaattttgt gctgaaaatg tgactttact tgaaaaagcg atgcaggctg gagctcgtcg
    37321 gattgaactc tgtgataatc tagcagttgg tgggacaaca cccagctatg gagtgactaa
    37381 ggcagcggtt gaactggcag ctaactacga tacaaccatc atgaccatga ttcggccacg
    37441 tggtggtgac tttgtctata atgacctaga aattgctatc atgctagaag acattcgttt
    37501 gactgctcag gctggaagtc aaggggttgt atttggaact ttaactgctg ataaaaagtt
    37561 ggataagcct aatctggaaa agttaattgc tgcatcaaaa ggaatggaaa ttgtctttca
    37621 catggccttt gatgaactaa gtgatgaaga tcaaccggaa gctattgact ggctcagtca
    37681 agccggtgtc actcgtatcc taactcgtgc tggtgtgtct ggcgactcct tagaaaaacg
    37741 ttttgttcac tatcacagaa ttttggagta cgctaaaggt aaaattgaaa ttctaccagg
    37801 tggggggatt gaccttgaaa accgtcaaac ctttatcgac caggtggggg taacacaatt
    37861 gcatggtact aaggttgttt tttaaaaaat agaaaggaac tgctagcttt gggtagcagt
    37921 tttcacttat gtttgaaatt tttaaatcct atcaatttaa tcaagaaaag gctcatgatt
    37981 atggttttat agaaaatagc gaagtctgga catatagttg ccagattttg caaggtgact
    38041 ttgtcatgac tgtgtccatc actgctgata atgtgaactt tcaagtcttt gaccaagaga
    38101 ctggtgacct ctatcctcac gttcatatgg aaagcatgag gggaagtttt gtcggaaatg
    38161 tccgtgaggc ttgtctggag attctttacc agattcggaa ggcttgtttt gatgtgcaag
    38221 attttatctg tcatcagact aagcgtatca tgactcaagt tcaggaaaag tatggaaacc
    38281 agttggagta tctgtgggaa aaatcgcctg atacagctgt attgcgccat gaaggcaatc
    38341 aaaagtggta tgccgtcttg atgaaaatct cttggaataa gctggaaaag ggcagagaag
    38401 gacaagtgga agcagtcaac ctcaagcatg accaagtagc taatttgctt tcacaaaagg
    38461 ggatttatcc agccttccat atgagcaagc gctactggat tagtgtgtcc cttgatgata
    38521 ctttatcaga tgaagaagta ctggaattga tagaaaaaag ttggaactta acctctaaaa
    38581 aatgaaatat tttaataatt ttcatgaact ttcaattggc taaatattct ttactgaaga
    38641 aattttcaga aaatatagga tttaccacac cagaggaata tggtgccatc ttcaaatacc
    38701 tgattgagaa tgtcaagacg gatcgtcaga tcatctattc gcctcactgt catgatgacc
    38761 tcggaatagc agtggcaaat agccttgctg ctgtcaagaa tggtgcagga cgtgttgaag
    38821 agactatcaa tggtattagg gagcgagctg gaaatgctgc tttggaagaa attgcagtgg
    38881 ctctcaatat tcgccaagat tactaccaag tagaaaccag tattgtccta actgagacca
    38941 tcaatacgtc agaaatggtt tctcgcttcc ctggtattcc agttcctaaa aacaaagccg
    39001 tcgttggtgg caataccttc tcccacgaat ctggtattca ccaagatgga gtccttaaaa
    39061 atcctctcac ttatgagaac atcacacctg aattggttgg tgttaagatt ccgcttggaa
    39121 aattatctgg tcgccatgct tttgttgaga aactgagaga attggcccta gattttacag
    39181 aagaggatat caaaccactc tttgctaagt tcaaggcact ggccgataag aagcaagaaa
    39241 tcacagatgc agatattcga gctttggtag ctggaaccat ggttgaaaat ccagaaggct
    39301 tccactttga tgatttacaa cttcaaactc atgcagataa tgacattgaa gcgctcgtta
    39361 gcctagccaa tatggatggt gagaaagtcg aatttaatgc gacagggcaa ggttccgttg
    39421 aagcaatctt taacgctatc gataagttct ttaatcaatc tgttcgtttg gtgtcctaca
    39481 ctatcgatgc gataacagat ggaatcgatg cccaggatcg ggttttggtc actgttgaaa
    39541 acagagatac agaaaccatc tttaatgcaa cagggcttga ttttgatgtg ttgaaggctt
    39601 ctgctattgt ctatataaac gctaatacct ttgttcaaaa agagaatgca ggtgagatgg
    39661 gacgcagtgt ttcttaccac gatatgccta gtgtgtaaag gagaaggcta tggcaaagaa
    39721 aatagtagct ctagtaggag acggaattgg cccagaaatc atggaggctg gtttagaagt
    39781 tctggaggct ctagctgaaa aacaggtttt gactatgaga ttgacagacg accgttcgga
    39841 ggtgcagata ttgatgcagc aggacctccc ttacctgatg aaacccttaa ggcaagtagg
    39901 gaagcagatg ctatcctact agcagctatc ggtagtcctc agtatgatgg agcagcggtt
    39961 cgccctgaac aaggcctgat ggctctccgt aaggaactca atctttacgc taatattcgt
    40021 cctgtaaaaa tctttgacag tctcaagtat ttgtcaccac ttaaaccgga acgaatttct
    40081 ggtgtagact ttgtcgtggt gcgtgaattg acaggcgaga tttactttgg agatcatatt
    40141 cttgaagagc gcaaagcgcg tgatatcaac gactatagct atgaggaagt ggagcggatt
    40201 attcgcaaag cctttgaaat tgcaagaaat cgcagaaaaa tcgttactag tatcgataag
    40261 caaaatgttc tagcgacctc aaaactctgg cggaaagtag ctgaggaagt cgcacaggat
    40321 ttcccagatg taaccttgga acaccagctg gtagactcag ctgctatgct tatgattacc
    40381 aatcctgcta agtttgatgt tattgtaacg gagaatcttt ttggagatat tttatctgat
    40441 gaatcaagcg tcttatctgg tacacttggg gttatgccat cagccagtca ttctgaaaat
    40501 ggaccaagtc tctatgaacc tattcacggt tcagcacctg atattgcagg tcaaggaatt
    40561 gccaatccta tttccatgat tttatcagtt tccatgatgt tgagagatag tttcggacgt
    40621 tatgaggatg cagagcgtat caaacgtgct gttgagacaa gtctggcggc aggaatttta
    40681 acgagagata taggaggtca ggcttcaaca aaggaaatga cggaagctat tattgcaagg
    40741 ttatgaagtt agacgaaaaa attactctag tccttttgat ttggaatgtc atcattttct
    40801 tgatttatgg cattgacaaa ttcaaggcaa gaagaagagc ttggcgcatc caagagaaaa
    40861 tcttactcat tttagccctt acttgtggtg gttttggggc ctggttagct ggaatcactt
    40921 ttcaccacaa gactcgaaaa tggtacttta aaacagtttg gtttcttggg atggtgacca
    40981 cactagtagc cttatatttt atttggaggt aatggatggc agggtcttcg agggaacacg
    41041 ctgcttgggt tctagcggac tatggcttta aggtcgtgat tgcaggatct ttcggtgaca
    41101 ttcattacaa taatgaactc aataatggcc tgttgccaat cgttcagcct agggaggtta
    41161 gagaaaagct agcccaactc aaaccgaccg accaagtaac tgtagacttg gaacaacaga
    41221 aaattatctc accagttgaa gaattcacct tcgagataga tagcgagtgg aaacataaac
    41281 tcctaaatag tttggatgat atcggtatta ccttgcagta tgaagagttg attgctgctt
    41341 atgaaaaaca acgaccagcc tactggcagg attagaaaaa atagaaaagg aaatatagta
    41401 aactgaaata agatgtaaac aaatgaatta gagcttaaca tccatttcca gcaatttttt
    41461 agaaactaca gtggactatt ctggattcaa cacattataa aattatgaca aaacacattc
    41521 acaagaaggc tacgacattt taaaaggtga gggcggatgt atcgtttgcc ctactaaagt
    41581 tggttacatt atcatgacca gtgacaaggc aggacttgag cgtaagttcg cagccaaaga
    41641 gcgtaagcgt aacaaaccag gtgttgttct ctgcggtagc atggatgaac tttgcgcttt
    41701 agcgcaactc aacccagaaa ttgaagcatt ctactaaaaa cattgggatg aagatattct
    41761 tcttggttgt atccttcctt ggaaaccaga agcctttgaa aaactcaaag catacgggga
    41821 tggccgtgaa gaacttatga ctgatgtacg tggtactagc tgttttgtta tcaagtttgg
    41881 aaaagcaggt gaacaattgg ctgccaagct ttgggaagaa ggtaaaatgg tctacgcgtc
    41941 atctgcttca atgacaaaac gattgaaact cgctatgagc aaggtgtaat ggtgtctatg
    42001 gtcgataagg acggcaaact catcccagaa caaggaggag cacgttcaac ttcaccagct
    42061 ccagttgtga tccgtaaagg gcttgacatt gatatagtaa aatgaagtaa gagcaggaca
    42121 aattaatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag gtgtactatt
    42181 ctagtttcaa tccactataa aatcatgatg cacctgtcag atacttttaa ctcatgggac
    42241 taccgtcagg ttgagtatta ttaggataga gaagaagtct agtgttaagg acattacagc
    42301 tcataatact aggctttttt atagaaattc ttttcttttt ctataggata tggtattcta
    42361 tgtagaaaat atatgttaat aagtaatgcc aatatttaaa catcattagt aaaaggagtt
    42421 agattgatga ataaaagaaa agttagttta gaagattttt ataaatggta tagtctaaat
    42481 aaagaagagt tattaaataa ggcaactgtt ggtgaaaagt ttaatgataa attaaaagaa
    42541 gagtttctcc aggaatggcc tttggatagg attttaacaa tgtcaatcga tgaatatgta
    42601 ataggaaagg gacagcaaaa taagtcttta tgctacgctc ttgagaaggg aaaatacaaa
    42661 aatctatttc ttggaatttc tggtggctca gcttcaaaat ttggtattta ttggaataaa
    42721 aaaacaaaca aatataaaga tcaagctaat aatgagattt cagagttgga tcagcgattt
    42781 tcaaaattaa aatcagattt gtatgaaatt atcaaagaag gtattcgttt taactttgaa
    42841 aatcctattt ttgatatgaa aagatcaaca aatgaattta ttggtcgttc tgctatggtg
    42901 acaaaattac tttgtatcta ttctgaggga gatcctttct ttggtgtaaa tattaatagt
    42961 cagaaagaat tttggaacca ctttgtttct cagacaaatc aaggtggacc ttatctgcaa
    43021 aatcataaaa taattgaact ggtgtccaaa acttatcctg agttggagcc atcgaaagta
    43081 ggaactatgc tttttgagta ttctaagctt tttatggaaa ataaggaaga caatagtaca
    43141 atggattcat caaacaattt tcgtcatcaa ttaactcaat ctctattaaa gtctccaaac
    43201 cttatccttc gtggtgctcc tggcacagga aagacttatc ttgctaaaga aattgccaaa
    43261 gaattaacgg atggcaacga agaccaaatc ggatttgtac aatttcaccc atcatatgat
    43321 tatacggatt ttgtagaagg tttaagacca gtatcaaatg gggatggagc tattgagttt
    43381 aggctacagg acggtatttt taaagatttt tgtcagaaag caaaagaaac ccaattgatt
    43441 ggaggacaag ataattttga tgaggcttgg gattcttact tagaatatat aaatgttgct
    43501 gaagaaaaag aatatataac aaaaacatct tacttatctg ttaatagtag acaaaatttg
    43561 tcagtaaatt atgatagtgg tgttccagga tggtcactac ctagcaaata tgtttacgag
    43621 ttgtataaag ataaaaatta taataagcaa gaatactaca aaagtggtgg aaaaactgtc
    43681 ctagaaacat tgagaaagag atttggtttg aaagactatg tttccccaac agaaattgat
    43741 actgataaga aattcgtctt catcatcgat gaaatcaatc gtggggagat ttctaagatt
    43801 tttggcgaac tctttttctc tatcggccct ggctatcgtg gtgaaaaagg aagtgtttct
    43861 acccaatatg caaatctaca cgaaactgat gaaaagttct atatccccga aaatgtttac
    43921 atcatcggaa ctatgaatga tattgatcgt tcagtggata cctttgattt tgctatgcgt
    43981 cgtcgttttc gttttgttga agttactgcc gagggtcaag ttggcatgtt ggataaagag
    44041 ctgaatatcc atgcagaaga agcaaaaatt cgtctaagaa acttgaacgc tgctatcgaa
    44101 aatgttcagg aattaaacag tcattatcat attggaccaa gttattttct taagttgaag
    44161 gatgtagatt ttgactatga attactctgg tctgattata ttaagcctct cctagaagac
    44221 tacttgcgag gttcttatga tgaggttgaa actttggaaa ctttgaaaaa agcatttgaa
    44281 ctgacaaata atgagcaaaa agatcaggca gtagctgatg acaatgaagg tgatgaaaac
    44341 gatgatgcgg attactgata atcaacacaa gattattaaa gaaaaatttg ttgaagaata
    44401 tcctaaacta agcaatcttc ttttagacag aaccttggaa agtttatccc aagatgaacg
    44461 tattttcatt tttccaaatg atttgactca tactcctgat ttggataagg accaaaagat
    44521 ttttgaaaca gtcaatcaga aaatcaagac agggaacgtg attggttttc ttggatatgg
    44581 tcaggaaaga ttaacgattt cctcacgatt ttctgatgag agtaatgacc attttttgca
    44641 ttatctctta aacaaggttc ttcatatcaa tctcactagt ttagatgttg ctttgtctcg
    44701 tgaagagagg ctttatcaac ttttggtgta tctctttccc aagtatctac aagctgctat
    44761 tcgaaaaggt ctttataagg aatatcatcg attttctcat aacgacagta atgttaaggg
    44821 agtgattgat gtaagaagcc atctcaagaa aaatcttcct ttcacgggaa atattgccta
    44881 cgcaacgaga gagttcacct atgataatcc cctcatgcag ttggtccgtc acactattga
    44941 atacattaag aatcagaaaa gcattggtca aggggtacta gataatctct caactagtcg
    45001 tgaaaacgta tctgaaatcg tgcgtgtaac gccctcttat aaactagctg atcgtgctaa
    45061 gattattcgg ggaaatcaat ctaaacctat acgtcatgca tactttcacg agtacagaaa
    45121 cttacaagaa ctttgtctga tgatcctaaa ccaagaaaag cacggtttag ggtatcaaga
    45181 tcaaaaaatc tatggtattc tctttgatgt tgcctggctt tgggaagagt atgtttacac
    45241 cttgttgcca aaaggttttg tacatcccag aaataaggat aagacggatg gaatttcagt
    45301 attttctgtt gggaaacgaa aagtatatcc agatttttat gacagagaac gaaagattgt
    45361 tctagatgca aaatataaaa aactggaatt gactgaaaaa ggaatcaacc gtgaggactt
    45421 attccagctg atttcctatt cttatatttt aaaagctgag aaggctggac tgatttttcc
    45481 tagtatggag cagtcagtaa atagtgaaat aggaaaagta gctggctatg gagctcaatt
    45541 gaaggagtgg tctattcgaa tccctcagaa tgcctcattc tatagtacat tttgtaaaat
    45601 gatggaaaat tcagaagaaa attttaaagc gattattgat gaagaagtgg ggagaaaata
    45661 atttcccctc tttcttttat ttttaacaca agtaaaaccc gaacgatata ttttaattca
    45721 taaaataatt tgacaaaaac tgtactttgg tttataataa attaaggaaa cgtcggaaaa
    45781 ggcgtagtga tgcaagagca taggtaggtc attacaaaag aaacgagaca tcgatatgtt
    45841 aaatgaattt ccaatttttg attacgaaga tattcaattg attccaaata aatgtgtcat
    45901 taaaagccgt gcagaagcgg atacaagtgt cactttagga aatcacacct ttaaactacc
    45961 tgttgtgcca gcgaatatgc agacgatttt ggatgaaaat gtagcagagc aactggctaa
    46021 aggtggttac ttctacatta tgcaccgttt tgatgaggca ggacgcattc cttttattaa
    46081 acgaatgcac aatcaagggc tcattgcttc catatctgtc ggtgttaagg actatgagta
    46141 tgatttcgtt agacagctca agactgatgc tcctgagtat atcactattg atattgctca
    46201 tggtcatgcg gatagcgtga tttctatgat tcaacacatc aagaaagaat tgccagatac
    46261 ctttgtcatt gctggaaatg tgggaacacc agaagctgtg cgtgaattgg aaaatgctgg
    46321 tgcggatgct actaaggtcg gaatcggtcc tggtaaggtt tgtatcacca aggttaagac
    46381 tggttttggt acaggtggtt ggcagttggc tgctctacgc tggtgtgcca aggctgcgcg
    46441 taaaccgatt atcgctgatg gaggaattcg tactcacggt gatattgcca agtctatccg
    46501 cttcggtgct agcatgatca tgattggttc cctctttgca ggacatattg aaagtccagg
    46561 gaaaacgatt gaagtcgatg gtgaacagtt caaagaatat tatggttcag cctcacaata
    46621 tcaaaaaggt gcttacaaaa atgtggaagg caaacgtatc ttgcttccta ctaaaggtca
    46681 tctgcaagac actttaactg agatggaaca agaccttcaa agtgctattt cttatgcagg
    46741 tggacgtcag gttgctgacc ttaaacacgt tgattatgtg atcgtgaaaa actccatctg
    46801 gaatggggat gcttcccact aagacggggt ctttgactaa aaaacttgtt attagagcaa
    46861 atttctgtta taataaaaca agtttccacc cttagtgtaa tggatatcac gtaagattcc
    46921 ggttcttgag atgggggttc gattccctca gggtggatgt aaacattcta aaaagccttt
    46981 aatagggctt ttttctttac actactctaa atttgccact aaaactgaga atctctgtct
    47041 aaagaattcc caaatgcttt ccagtcccgt tttagagtga ctcagggggc tttttttgat
    47101 ataataaaaa ggactgttat cagttagaaa gaggttggta tgaaagaatt acaaactgta
    47161 ctaaagaacc attttgcaat cgaatttaca gacaaaaagt tactggaaac tgcctttact
    47221 catacgagtt atgccaatga gcaccgcctc ttaaaaattt cacataatga acgcttggaa
    47281 tttttaggag acgctgttct acagttattg atttcagaat atctgtataa aaaatatcct
    47341 aaaaagcctg aaggtgacct atcaaaactc cgtgctatga ttgtccgtga ggagagttta
    47401 gctggttttg cgcgtgattg ccagtttgac cagtttatca agttgggtaa aggggaagaa
    47461 aaatctggtg gtcgcaatcg tgacaccatt cttggtgatg cctttgaagc ctttcttggt
    47521 gcccttcttt tggataagga tgtggccaag gtcaaggaat ttatctatca agtcatgatt
    47581 cctaaggttg aagcaggcga atttgagatg attacagact ataaaaccca tctccaagag
    47641 ttacttcagg tcaatggtga tgtggctatt cgttatcagg tgatttctga aacagggcct
    47701 gctcacgata aggtctttga tgtagaagtt cttgttgaag gtaagagcat cggtcaaggc
    47761 caaggtcgtt ctaagaaatt agcagagcag gaagctgcca aaaatgccgt tgagaagggg
    47821 ctggattcat gtatttaaag gaaatcgaaa ttcaggggtt caagtctttt gctgataaga
    47881 ccaaggtcgt ttttgaccaa ggtgtgacgg cagttgttgg acccaatgga tctggaaagt
    47941 ccaatattac agaaagtctg cgttgggctt tgggggagtc tagtgtcaag agtctccgtg
    48001 ggggcaagat gccggatgtc atctttgctg gaacagaaag tcgcaaaccg ctcaattatg
    48061 cttctgtagt tgtgactctg gataatcatg acggatttat caaggatgca ggtcaagaaa
    48121 tcagggtgga acgccatatc tatcgtagtg gagatagcga atacaagatt gacggcaaga
    48181 aagtccgtct gcgtgatatt catgaccttt tcttggatac aggtttggga cgagattcct
    48241 tctctattat ttcccaaggg aaggttgagg agatttttaa ttccaagtct gaggaacgac
    48301 gagctatttt tgaagaagct gctggagttt taaaatacaa gactcgcaga aaagaaaccg
    48361 agagtaaact gcagcaaact caggataatc tggaccgctt agaggacatt atctacgagt
    48421 tggataatca aatcaagcct cttgagaagc aagctgagaa tgcccgtaaa tttctagact
    48481 tagaaggtca acgcaaggct atttacttgg atgtattggt tgctcaaatc aaggaaaata
    48541 aggcagaact agagtcgaca gaagaagagt tggctcaggt tcaagaactc ttgatgagtt
    48601 attaccaaaa gcgtgaaaaa ttagaagaag aaaatcaaac tcttaaaaag caacgccaag
    48661 atttacaggc tgaaatggcc aaagaccaag gcagtttgat ggacttgact agtctgatta
    48721 gtgatttaga aagaaaatta gccctatcga aactggagtc tgagcaagtg gccttgaatc
    48781 aacaggaggc acaagctcgt ttggctgctt tggaggataa gagaaattca ctcagcaaag
    48841 aaaagtctga taaagaaagc tctttagctc tgttagaggg aaatctagtc caaaataatc
    48901 aaaaactcaa tcgtttagaa gctgaattgc tggctttctc agacgatcct gatcagatga
    48961 ttgagctctt acgtgaacgc tttgtagctc ttttacaaga agaagcggat gtctcaaacc
    49021 agttgacccg tattgagaat gagttggaaa atagtcgtca gctttctcaa aaacaagcag
    49081 atcaactaga aaagctgaaa gagcaattag ctatagctaa agagaaggct agtcagcaaa
    49141 aggaagagct tgaaactgcc aaggagcagg ttcagaaatt attggctgac taccaagcta
    49201 ttgccaagga gcaagaggag cagaaaactt cctatcaagc tcaacaaagc caactctttg
    49261 accgtctgga taatctcaaa aacaagcagg ccagagctca aagtttggaa aatatcctga
    49321 gaaatcatag taacttttat gcaggtgtta agagtgttct ccaagaaaaa gatcgcctag
    49381 gtgggattat tggtgcagtc agtgagcatc tgacctttga tatgcattat caaactgccc
    49441 tagaaattgc gcttggagcg agtagccaac atatcatcgt agaagatgaa gagtcggcaa
    49501 ccaaggctat tgacttcctt aaacggaaca gagccggtcg tgcaaccttt cttcctttga
    49561 ccactatcaa ggcgcgtacg atttctagtc agaaccaaga tgctatcact gtaagcccag
    49621 gtttccttgg gatggcagat gagttggtga cttttgatac tagactggaa gccattttca
    49681 agaacttgct agctacgacg gctatctttg atgccgtaga acatgcgcgt gcagcagctc
    49741 gccaagttcg ttatcaggtt cgtatggtga cattggatgg gacagaatta cgcacgggtg
    49801 gttcctatgc gggtggtgcc aatcgccaaa ataacagtat tttcatcaag ccagaactgg
    49861 agcaattaca aaaagaaatt gctgcagatg aagcaagctt gcgttcagaa gaagcggctt
    49921 tgaagacctt acaagaccag atggctacat tgacagaaag attagaagtc atcaaatctc
    49981 aaggagaaca ggcacgtatt caggagcaag gcttgtccct cgcttatcag caaactagtc
    50041 agcaagttga agaactggaa actctttgga aactccaaga agaggaaata gatcgtcttt
    50101 ccgagggaga ttggcaagcg gataaggaaa aatgccaaga tcgtcttgct gcaatcgcca
    50161 gtgacaagca aaatctggaa gctgagattg aagagattaa gtctaacaaa aatgccatcc
    50221 aagaacgcta tcaaaacttg caggaagagc tagcgcaagc tcgtttgctt aagacagaac
    50281 tgcaagggca aaaacgttat gaagttgctg atattgaacg cttaggcaag gaattggaca
    50341 atcttgattt tgaacaagag gaaatccagc gccttcttca agaaaaggtt gataatcttg
    50401 agaaggttga tacagaattg ctcagtcaac aggcggaaga agccaaaact cagaaaacaa
    50461 atctccaaca aggtttgatt cgcaagcagt ttgagttgga tgatattgaa ggtcaactgg
    50521 atgatattgc tagtcatttg gatcaggctc gccaacagaa tgaagagtgg attcgcaagc
    50581 aaacacgtgc tgaagccaag aaagaaaagg ttagcgagcg cttgcgctat ttacaaagtc
    50641 aattaacaga ccaatatcag attagctata ctgaagctct agaaaaggcg catgaattgg
    50701 aaaacctcaa tctggcagag caagaggtgc aggatttaga gaaagctatt cgctcactgg
    50761 ggcctgtcaa tatagaagct attgaccagt acgaagaagt tcacaatcgt ctggatttcc
    50821 taaatagcca acgagatgat attttgtcag cgaaaaatct gctccttgag accattacag
    50881 agatgaatga tgaggtcaaa gatcgcttta aatcaacctt tgaggccatt cgtgaatcct
    50941 ttaaagtgac cttcaaacag atgtttggag gaggtcaggc agacttaatc ttgactgagg
    51001 gagacttgtt gacagctggg gttgagattt ctgttcaacc tccaggtaag aaaatccagt
    51061 cgcttaacct catgagtggt ggtgaaaaag ccttatcagc tcttgctttg cttttttcta
    51121 tcattcgagt taagactatc ccatttgtca tcttggatga ggtagaggcc gcgctggacg
    51181 aagccaatgt taaacgtttt ggggattacc tcaatcgatt tgacaaggac agccagttta
    51241 tcgtcgtaac ccaccgtaag ggaaccatgg cagcggctga ttctatctat ggagtgacca
    51301 tgcaagaatc gggggtctca aaaattgttt cggttaagtt aaaagattta gaaagtattg
    51361 aaggatgaca attaaactag tagcaacgga tatggacgga accttcctag atgggaatgg
    51421 acgctttgat atggaccgcc tcaagtctct cttagcttcc tacaaggaaa aagggattta
    51481 ctttgcggtg gcttcggggc gcggatttct gtctctagaa aaattatttg ctgatgttcg
    51541 tgatgacatt atttttatcg cagaaaatgg cagtttggta gagtatcgag gtcaagactt
    51601 gtatgaagcg accatgtctc gtgagtttta tttgacgact tttgaaaagc tgaaaacttc
    51661 accttatgta gatatcaata aattgctctt gacggggaaa aagggagctt atgttctaga
    51721 tacggttgat gagacctatt tgaaagtgag tcagcactat aatgaaaata tccaaaaagt
    51781 agcgagtctg gaagatatta cagatgacat tttcaaattt acgaccaact tcacagaaga
    51841 aacgcttgaa gctggggagg cttgggtcaa tgaaaatgtc cctggtgtta aggccatgac
    51901 aactggcttt gaatccattg atattgttct ggactatgtt gataagggtg tggccattgt
    51961 tgaattggct aaaaaacttg gcatcataat ggatcaggtt atggcttttg gagacaatct
    52021 aaatgatttg catatgatgc aggttgtggg acatcctgta gctcctgaaa atgcacgacc
    52081 tgaaatttta gaattagcaa agactgtgat tggtcaccat aaggaccagt cggttatagc
    52141 ttatatggag ggcttataat ggcagatata aaattaatcg cattggactt ggacggtacc
    52201 ttgctgacta ctgataaaag gctgacggat cgcaccaagg caactttgaa agctgcgagt
    52261 gatcgtggta tcaaggtcgt attgacaact ggtcgtccct taaaagccat ggacttcttt
    52321 ctccatgagt tagggactga cggccatgaa gatgagtata ccattacttt taatggtgga
    52381 ttagttcaga aaaatacagg agaaatcctt gataaaacag tcttttcata tgatgatgtg
    52441 gcacgtttgt atgaggaaac agagaaatta tcactgcctc ttgatgccat ctcagaagga
    52501 acagtttatc aaatccaatc ggaccaagaa agtctttatg ccaaattcaa tccagctttg
    52561 acttttgttc cagttgactt tgaagacctg tctagtcaaa tgacctacaa caaatgcgtg
    52621 actgcctttg ctcaagaacc cttggatgca gccattcaga agatttctcc agaattgttt
    52681 gaccaatatg aaatctttaa atcacgtgaa atgttgctag aatggtcacc aaagaatgtt
    52741 cataaagcaa caggtttggc aaaactaatt agccatcttg gaattgatca aagtcaagtg
    52801 atggcctgtg gtgacgaggc caatgacctc tctatgattg aatgggcagg gctcggtgtt
    52861 gccatgcaaa acgctgttcc tgaagtaaag gcagccgcaa atgtagtgac gccgatgacc
    52921 aacgatgagg aagctgtcgc ctgggctatc gaagaatatg tgctaaagga gaactaagat
    52981 atgggattat ttgaccgtct attcggaaaa aaagaagaac ctaaaatcga agaagttgta
    53041 aaagaagctc tggaaaatct tgatttgtct gaagatgttg atcctacctt cacagaagtt
    53101 gaagaagttt ctcaagaaga agctgtgctt gaagaaagtc aggattcaga gccagctgta
    53161 ggggtttctc aagaagaaat agaagaatta ccagaggaag agaagcttga gcacgaagga
    53221 actatagaag aaaataattc tgaagttctt gaagcagaaa ggcctcaagc agaagaaacc
    53281 gttcaggaaa aatatgaccg cagtcttaag aaaactcgta caggtttcgg tgcccgcttg
    53341 aatgccttct ttgctaactt ccgctctgtt gacgaagaat tttttgagga actggaagaa
    53401 ctgctgatta tgagtgatgt tggtgtccaa gtcgcttcta acttaacgga ggaactacgt
    53461 tacgaagcca agcttgaaaa tgccaagaaa cctgatgcac ttcgtcgtgt catcattgag
    53521 aaattggttg agctttatga aaaggatggt agctacgatg aaagcatcca cttccaagat
    53581 aacttgacag ttatgctctt tgttggtgtg aatggtgttg ggaaaacaac ttctatcgga
    53641 aaactagccc accgctacaa acgaactggt aagaaggtca tgctggttgc agcagatacc
    53701 ttccgtgcgg gtgcagtagc tcagctagct gaatggggcc gacgagtaga tgttccagta
    53761 gtaactggac ctgaaaaagc tgatccagcc agcgtggtct ttgatggtat ggaacgtgcc
    53821 gtggctgaag gtatcgatat tctcatgatt gatactgctg gtcgtctgca aaataaggat
    53881 aaccttatgg ctgagttgga aaagattggt cgtattatca aacgtgttgt gccagaagca
    53941 ccacatgaaa ccttcttggc acttgatgca tcaacaggtc aaaatgccct agtacaggcc
    54001 aaagaatttt cgaaaatcac acctttaacg ggaattgttt tgactaagat tgatggaact
    54061 gctcgaggag gtgtggttct agccattcgt gaagaactca atattcctgt aaaattgatt
    54121 ggttttggtg aaaaaatcga tgatattgga gagtttaact cagaaaactt tatgaaaggt
    54181 ctcttggaag gcttaatcta atcagaagca aaaatcctgc aaggtacaaa cttgcaggat
    54241 ttttttattc gaaacgacca tcttgacgat aggcgatatc tggttgccaa gtccatttgg
    54301 catcgaattt ttcaagtagg tcaaagctgg cttgaggtcc catgcttcca gctttatagt
    54361 catgaagtgg ggcaccattt tcggcccaga gctcttcaat acggtcaatc aacttccatg
    54421 acgcaccaac ctcatcccag tggctaaagt tagttgagtt gttatttagg acatcataaa
    54481 tcaatttctc gtatggttct ggagaagcac cagttgcagt cgcgtctgta cgataatcaa
    54541 gtgagttagg agccaagtta aattcttctc ctacttgctt cccatttagg ctaagagaga
    54601 agccttctgt tggttgaata tagatggtca aaatatttgg agcaagtggt tctccaaaga
    54661 tagaatccat ttgtttaaag acgatgttga catgagttcc tttttcagtc agtcgtttac
    54721 ctgtacggaa aaagaaagga acaccacgaa atcgatcgct gtctacaaag aaggcaccag
    54781 atgtaaaggt ttcagttgtt gattctggat tcacatttgg ttcgctacga taagagatgt
    54841 atttcatgcc atcaatctta ccagagcggt attgtccacg gataaagtgt tctttgagtt
    54901 cttcatcagt tggatgatag aggtttttaa agaccttaat cttttcagca cgaatctcgt
    54961 cttttgtgaa gcttgctggt ttgtccatgg cgaggagcga aagaagttgt agagtgtggt
    55021 tttggaccat gtcacggagg gcaccggatt ggtcatagta gccaccacgt tcttctacac
    55081 ccaagcgctc cgcaaaggta atttgaacat tgtcgataaa atccttgttc caaacgtttt
    55141 caaaaatcaa gtttgcaaag cgaactgcaa agatgctttg gatcatttcc ttaccaagat
    55201 aatggtcaat acggaaaatt tgttcttcgt caaatgttgc taggagttca tcattcaact
    55261 tgcttgcagt tgcgtaatct gtaccaaatg gtttttcaac gatcaagcgc tcaaaacctt
    55321 tgccatcgac aatgttttca gatttgaggt gtttggcaat ggttccaaag aactgaggtg
    55381 ccatagacaa gaagaagagc ttattgtgtt cagcttggta tttttcatta agctcagctt
    55441 gtaattgacg caaagcaata taatgttccg aatcattgac atcatggctt tgatagtaga
    55501 agtggctagc aaattcttgg gcttgctcgg tactatctgc caaatcaagg atggactcga
    55561 caactacaga ttcaaaatat tccttactcc aaggtctacg ggcagttcca ataacggcaa
    55621 agtgcttgga aagattgccg gattgatata gtctaaaaag ggaagggtag agcttgcgtt
    55681 tagccaggtc tccactcgca ccgaaaattg taacaataac cttagatgac atctagctac
    55741 ctaatttcta tttttattcc tagtcttgct aggtatgagg aaacctcatt tcataaactt
    55801 aattctaaca taattttccg aaaaatcaaa aattccaata cgaggtagaa aaactgcaag
    55861 gaaatcctta cagtttgagt ttagacgttt aagaccttat ctaagaactc tttcagacga
    55921 gggtgttgtg ggttatcaaa gatttggtca ggtgttccgt cttcaaggaa ctcgccatct
    55981 gcagtaaaga taacgcggtt ggcaacctga cgagcaaatc ccatctcatg ggttacgata
    56041 atcatggtca tgccttgctc agccaattcc ttcataacgt taagtacgtc tccaaccatc
    56101 tcagggtcaa gggcagaagt tggttcatcg aagagcatga tgtctggatt cattgctagg
    56161 ccacgagcga tggccacacg ttgtttttga ccacctgata ggctatctgg attggcatta
    56221 gctttatctg ctagtccaac cttttcaagc aactccattc ccaattcctc agcttcttcc
    56281 ttagtcatca acttgtgctc aataggagca aaggtgatgt tgtccaatac agacatatga
    56341 gggaagaggt tgaagtgttg gaataccatg ccgatatttt cacggacgtg gtcaacattg
    56401 gttgtttttt cagttaaatc atagccgttc acagtgatgt gaccgctagt gacttcttct
    56461 aaaagattga ggctacggag gaaagttgac ttaccagaac ctgaaggacc gatgatacaa
    56521 acaacatctc cttcatagaa cttagtcgta attcctttta ggacttcatt ttttccatag
    56581 tacttgtgta aatcatttac atcaattttt aattttgcca ttaacgaatc ctcttttcta
    56641 agcgtttcgc tagtctagtc aaaagtgtga taattacaag atagaagata gcaaggattg
    56701 catacatctt gaaactttgg tagttacgag caatgataat cttaccagtt tggaagagtt
    56761 caaccaaacc gatagcagat acgatagttg tatctttaag agcgataacg aattggttga
    56821 caaagtttgg caacatcaat ttagttgatt gtggcaagat aatcttacgc atggtttttc
    56881 cataagagat acccaagctt cggctggctt ccatttggcc aactggaacg gcctgaatac
    56941 caccacgaac gatttcagcg atataagcag ccgcattgag tgagagggca attgttccag
    57001 ctacaaagtc gttaattggg ctttgttggc ctgtgataga ctcgatgaag tttggaattc
    57061 cccagaagat gaaggctgca agaatcatca atggaatacc acgaataacg tcaacgaaaa
    57121 tctcagagat gacgcgaaga gatttgtatg ggctaacgct aaacataccg aagataattc
    57181 cgatgacaat ggcaatagca aatgagataa gagctagagc aagagtgata ccaagaccgc
    57241 taaggagttg tttgtagttg ttttgaagca agccccagag cgttgtttcg tcaacagtac
    57301 ttgttgaagc agttgaagat tcgctagcta ggtatttgtc aagaatcttt tggaattcac
    57361 cgtttgcttt aaggtttgca agtccgttgt tgaacatttc aatcagttct ggatttgctc
    57421 cttttttaac ggcaaaggct gtttcaccga ttggagttcc agagattgga gttttcaatt
    57481 tttgaccttg gctgatagaa tatttgagaa caggttcatc atccataacg gcatcaatgg
    57541 caccagtgtt taaactgtca tacattgaag aaccatcagc aaaggttttg attttgtaac
    57601 cgtatttgct ttgattttct gttaggaagg tttgagaagc agttccgttt ttaacaccga
    57661 ctgtctttcc ttttagatct tcataagaag caatattgct tgattctttg acaccaagaa
    57721 tggtattagc agtgtagtat gattctgaga agtcaaaagt tgccttacga gcatctgtga
    57781 cagacatacc agcaatgata ccatcggctt gaccagcttg gacagcactg atagcagcat
    57841 caaaaccagg gttggtgatt tcaatttcaa aaccttggtc tttagcgatt gccttaatca
    57901 attccatatc aataccagtg tattggttgc ttgaattttg gaaaacaaaa ggtgcaaaag
    57961 aagaatcgct ggcaatgata tatttagcct taacaggaat agcttttaat cctgcgagag
    58021 tagttgtagt tggcactgct gaagatgatg aagcagtcca tttcttgata attttatcaa
    58081 gactaccatc ttttttcatt tcagccaagg cttggttaaa ttcagtaacc aggtgctcgt
    58141 atttacttcc ttttttcaca ccgaaagcaa aacttcctac agcttcacca tccatttcaa
    58201 tatggaggtc ttgaccttgg ttaatggcat attcgataac aggtttgtca tccatcatgg
    58261 catcgatggc accagcactc aagctgttgt tcattaaatc accagtgtca aatgttttaa
    58321 tagtaaagcc gtatttatct ttgattgttt caaggaaacg ttgagcggca gttccgtttt
    58381 taacaccaac ggttttgcca gttaattggt cgtacttgct aattttgtgt gactttgtag
    58441 tagcaatgac aacttttgta tcatagtaag tatcagacat ggtgaagact ttttcacgtt
    58501 ctttagtctt tgtcatccct gccatgatag cgtcggcttg cccagcttga accgcattga
    58561 ctgctgcgtc aaatccagga taggacatct gaatgttcca gcctttaatc tcagcgactt
    58621 tgttaataat gtcaacatca attcctttat aagtttgatc tgaatcttta aactcaaaag
    58681 gtgcataggc ggtatcagaa acaatcttaa tcgtttctgc tttggcaata cctaatgaga
    58741 aaattgggaa taaaattagc aaaaatgcta gaaatttttt cttcattttt agtctccttt
    58801 tccgaatatt ctctcattat atcagaaaaa gtaaaaaaag gcaaattttt atatttttcg
    58861 tgtcagaaaa tataacattg atttttcctt ttctttcttg aattgctatt aaaaagtgat
    58921 ataataatag tatatataga agaaaagagg acggggatat gaagaacaaa agaatattta
    58981 aagacttcca agcttcaaaa atgaatttaa acatttacac aagccccttg ttagcctttg
    59041 tttttgtctt cataggagag tttgtggctt atactttata tggtattagt ttgttagctc
    59101 tcatcggact tgctagaaat tttggagagg ctggtcaaaa tcttgcaagc tacttgcaga
    59161 ccttgcatca gagcttgacg gataaaacaa gtgactttcg tttaatttta ggattactgg
    59221 cctttggttt tattcttaac actgtgttca gatggacaag aaaagttgag aaaagaccta
    59281 ttcgaacctt gggattttat agagagaatt tcctcagcaa tcttctgaaa ggatttagtc
    59341 taggtctggc actttttctt ctgaccttgt taggtttggt ggtcttaggt caatatcgtt
    59401 tggaatccat tcacttgaat ccttattctc ttgcctttgt cgtctttact atcccatttt
    59461 ggattttaca ggggacagca gaagaagtgg tggcccgtgc ttggctactt cctcaattgg
    59521 cctcaagaac caatctaaaa ctagctattc ttatatctag cctgttcttt accctgcttc
    59581 atatgggcaa ttctggtctc acccctctat ctctagtaaa tctcttttta ttcggagttg
    59641 ccatggctct ttaccttctc aaaactgata cagtttgggg tgttgcaggt attcatggtg
    59701 cttggaattt tgctcagggt aatctctttg ggattttagt tagtggtcaa ccgtcaggaa
    59761 cgtctctgat gaccttttta ccacaaggca atcaagattg gctatcaggt ggttcttttg
    59821 gcatagaagg ttccattatg acaagtctgg tattactact gctgattgtc tatcttgcta
    59881 ataaattaaa gaaagaaaat gaaaggatgt gacttcggtc cgtccttttc ttcgtgaaaa
    59941 tactataagt atgctaaaat aggaatagca catggagaga ggattcttat gatcaatcac
    60001 attacagata atcaatttaa actagtatca aaatatcaac catcaggaga tcaaccccaa
    60061 gctatcgagc agttggtgga taacattgag gggggagaaa aagctcagat tctgatgggg
    60121 gcgactggaa cagggaagac ctatactatg agtcaggtca tttctaaagt caataaacca
    60181 actctggtta ttgcccacaa taaaactctg gctggtcagc tctatgggga gtttaaggaa
    60241 tttttccctg aaaatgcagt tgagtatttc gtatcctact atgattatta ccagccagag
    60301 gcctatgtcc cttctagcga tacctatatt gagaaggata gttctgtcaa tgacgagatt
    60361 gacaagcttc gccactcagc tacctcagcc cttttggagc gtaatgatgt tattgtcgtg
    60421 gcctcagtct cttgtatcta tggtttgggt tcgcccaagg aatacgctga tagtgtcgtt
    60481 agtctccgtc ctggtctaga gatttctcgt gataaactct tgaatgactt ggtcgatatt
    60541 cagtttgaac gtaatgatat tgatttccaa cgcggaagat ttcgcgttcg tggggatgtg
    60601 gtagagattt tcccagcttc ccgagatgaa catgcctttc gagtagaatt ttttggagac
    60661 gaaattgacc gtattcgtga agttgaggct ctgacaggtc aggtgttggg agaagtggat
    60721 catttagcga ttttcccagc gacacacttt gtgaccaatg acgaccacat ggaagttgcc
    60781 attgcaaaga ttcaggccga gttggaagaa caattagctg tctttgaaaa ggaaggtaaa
    60841 ctgcttgaag cccagcgttt gaaacagcgg acagagtatg atatcgaaat gttgcgtgag
    60901 atgggctata ccaatggggt tgagaactat tcacgacaca tggatggacg gagcgaagga
    60961 gagcctcctt atacgctctt agatttcttc ccagatgatt tcttaattat gattgacgag
    61021 agtcacatga ccatggggca aatcaagggc atgtacaatg gagaccgttc gcgtaaagaa
    61081 atgctggtta attatggctt ccgattgccg tctgctttgg acaatcgtcc tctccgtcgg
    61141 gaggagtttg agagtcacgt tcatcagatt gtttacgttt cagcgacacc tggtgactat
    61201 gaaaatgaac agactgagac agtgattgag caaatcattc gtccaacggg actcttggat
    61261 cctgaagtgg aagtccgtcc gactatggga cagattgatg acctcttggg tgaaatcaat
    61321 gcccgcgttg aaaaaaatga gcgtaccttt atcacaactt tgaccaagaa aatggcagag
    61381 gacttgaccg actacttcaa ggaaatgggt atcaaggtca agtacatgca ctcggatatc
    61441 aagaccttgg aacggacgga gattatccgt gacctgcgct tgggtgtctt tgatgtcttg
    61501 gtcggaatta acctgctccg tgaaggaatt gacgttcctg aagtgagcct cgtagctatt
    61561 ctcgatgctg ataaggaagg tttccttcgc aacgaacgtg gactcatcca gactattgga
    61621 cgtgctgctc gtaacagtga aggccatgtc atcatgtatg cagacacggt tacccagtct
    61681 atgcaacgtg ctatcgatga aactgcccgc cgtcggaaaa ttcagatgac ctataatgaa
    61741 gagcatgata tcgtaccaca gacaatcaag aaagaaatcc gtgacctgat tgccgtgacc
    61801 aaggcagttg ctaaggaaga ggacaaggaa gtcgacatca atagcctcaa caaacaagag
    61861 cgcaaggaac tcgtcaagaa actagaaaaa caaatgcaag aagccgtcga agtgcttgac
    61921 tttgaactgg cggctcagat tcgtgatatg atgttggaag tcaaggtctt ggattagggg
    61981 aatagtatga tttatttaag aaagttaaag agagaagatt tgatgtcttt atgggaaatg
    62041 gcttattcac aacttaatcc agtttggaaa cagtatgatg ctccctatta tgatgattat
    62101 cagtattttt caaattttaa agaattcgaa ctacaaaaat cagaatccat tttaagcaac
    62161 tcaaatcgcc ttggtatttt tgttgatgat aaactagttg ggactgtttc gcgttattgg
    62221 gtatgtaaac aaacaagatg gatggaattg ggaattggta tttatgataa aaaattctgg
    62281 aacactggta ttgggaaagt tgctatgttg cagtggatag ataggacgtt tcaggattac
    62341 ttggagttgg agcatctggg tttgacaact tggtcaggga atcttggtat gatgaaactt
    62401 gctgaaaaat taagaatgaa aaaagaagct catattccaa aagttcgtta ttatcaaggt
    62461 aaatattttg atagtattaa atatggtatt ttgagagaag actgggagaa aataaatgac
    62521 ggttattatc aaatcaatgg aaactcctga agagatagaa ggtaaatccc ttgttcactg
    62581 gcaaacgtgg agagaggctt atgatgacct tttgcctgca gaatttcagg aaacaatgac
    62641 attagaaaga tgtcgattct ttagtcaaaa gtatccagaa aatacattga ttgcgataga
    62701 tgacctgaag gtagttggtt ttatcagtta tggcagcttt cgtgatgaga ctattcaagc
    62761 tggtgaaatt attgctttat atgttttaaa agactattat ggaaaaggaa tcgcacaaaa
    62821 gttagtgaaa gtagctttga ctgctcttaa tcatttttct gaaattttct tatgggtatt
    62881 gaaagataat aagcgcgcca ttgctttcta tcaaaaaatg ggttttactt ttgatggaca
    62941 agaaaagata cttgaacttg gaaagcctat aaaggaaaaa cggatggtat tctattctaa
    63001 ataattttaa aaagtaaaag ctaatatctc tggtaccaag tctgaaaatt taataaatta
    63061 gaaagcgagt aaatttatgt cccgttcaca attaacgatt ttaacaaaca tttgtctgat
    63121 tgaagacctc gaaactcagc gcgtggtgat gcagtatcgc gctcctgaaa acaatcgctg
    63181 gtctggttat gcctttccag gaggccatgt agaaaatggc gagtctttcg cagagtctgt
    63241 cattcgtgaa atctatgaag aaacagggtt gactatccaa aatcctcaac ttgtcggcat
    63301 taaaaattgg ccactggata caggtgggcg ctatattgtc atttgttata aggcaactga
    63361 gtttactgga actcttcaat cttcagaaga gggagaagtt tcttgggtgc aaaaagacca
    63421 gattccaaac ttggatctgg cctatgatat gctacccttg atggagatga tggaagctcc
    63481 tgataagtct gaatttttct accctcgccg tacagaagac gattgggaaa agaaaatctt
    63541 ctagtctttt actaaataac ctagctgatc caaggcctcc tcgatatagt ggaggtcttg
    63601 ttgtgtttcg gcttcgacta ggtggtaatg gatgccatct gtcaattcag atagaggtct
    63661 aaagtcagaa tgctcgactt gttctagaaa atgttgcaca tctctgcgac aagacagttt
    63721 aagcaaggtt tcaatttctc cataaacggg atggtcaatc aaggtattct ggacatgccc
    63781 accattatcg acaatagcaa ggagttcctg accgatttct tcaacttcat gtttcacttt
    63841 gaaaagtttg tgaacataag gattggtatc aatttgctta tagatgtagc cacgattggt
    63901 ggataggata ggagcgccat cggctctcaa aattgcaatg tcctgcacaa tgacctgacg
    63961 tgtgacatga aaatgttccg ccaaactttg gccattaagg gctttaggag cttctttcaa
    64021 gagttggagc agggcttgtt tgcgatcttt tgtcatagct tttcctttta acggcgtttt
    64081 cgaagcactt tatagacagc tagtgctaat gtatagtcta ccatactatg gataattgtg
    64141 ccaaatccaa ctagcacaaa tagaacatag aacatgtttt ctacattggt acccgaagtt
    64201 gcgtaaaaaa ggacacaggc taatacttca gcaagggcat gaacaacagc caaaacaaag
    64261 ttgaaaaccc aggaagattt tggtttatct agggtatcgg ggaatttttg taggtaaaga
    64321 gctcctaaag caccaaaaga tatatgggaa aaagcccgaa aaacgataac catgggatag
    64381 ccagccatca aaaatccaaa actagaggct aggatgacaa aaactgccat caagggcgac
    64441 aagaacatgg ctataaaaat agcgatgtgg ctccccaaag tataggaagc aggtggaatg
    64501 acaatcttga aaggcataac aattggaatc aaaatcgcaa tagccgttaa aagggctgtc
    64561 attgtcataa attgtgtctt tttccgtgta ttcacaagaa tctccttttt aactgcatat
    64621 acactagtat ggtacaataa accagacaat aaagcaagaa tttacttggg tttatagata
    64681 attttttagt taaaagttat agtagattga aactagaata gtccacctct acttctaaaa
    64741 cattgttaga aatcgatttg gctgtcctga tcgatttatc ctgttcttat ttcgttttac
    64801 tatagtaaag atttcattaa aaagaaactg tatagagcaa aatctccacc ttcaggtttg
    64861 aaagcggaga ttgtttttat tttttcaagg tttgtagtcg tggaacaatg gctagggtta
    64921 gaattgcaga aatgaccaat tcagcaattg aatttgttga gataacggtt gccagaagaa
    64981 gttggatatt tccattataa acatttccaa ataggaagaa gattcctcca aggacaaaga
    65041 tagtatttgt caaggaacca agggctccag ctaaaatcag accagtcttg tttttcatca
    65101 gtttatagac taagtaagga gttaaaccaa tcaaaatacg tgggacgatg gcaatgatag
    65161 ctgagtagat gtttccgttt ggtacgaagg gagagaagag gtagcttgtc ggtagaatcg
    65221 taatcgtgtt aaccgtcaag ctaagtaatc ccatcaaaaa tccaagtgta accccaactc
    65281 gtggaccata aataatgctg gcaataatga caggaatatg aacaatggtc ggtttgattg
    65341 gaaatggaaa aaggttaaag ataagtgagc tcagaaagtg tatcacgagc atggtagcaa
    65401 aaaagatagc aatgggtgca atattagagc gttttttcat cgatagtttc ctttattctt
    65461 tctaaaataa ttgtgaggtc agctaaagct cctcgtccgt ggtctccaca agctagtagg
    65521 gattccttag gagcaatcag ctgatagccg taggtttcta atgttttcag attattctga
    65581 gttactggat ggtcatacat ttttgtattc atagcaggag ctattagttt gggaatatga
    65641 cttggtaggg ctagagctgt actggttacc atgttgtccg caaatccgtg agctagtttt
    65701 gcaatagtgt tagcagttgc aggtaccacg ataaataaat ctgctttttt tccaagttcg
    65761 atatgattga cctgatcagg atagggttcc ttcatgacat ccaagtggac aggattctgt
    65821 gagagtacct gtagtgtcaa aggttggata aactctgtag cagcctgagt cattaagaca
    65881 gtgacttgat ggccttgttt ttttagagaa ctgactaaat ctgccgactt ataagaggcg
    65941 attgaacccg ttacagccaa gagaatgttt gccatagttt tcctttctaa gaatgatagg
    66001 cttgaatttt ttcaaggagg agttctgcaa tttcttcttt agtctggact gtttgaagct
    66061 gatttttctc aacaaatata gctcggtgct gatctgctga aatttgagtc aggtcattcg
    66121 cgatgattaa atctgcttga ttcttgataa gactttttcg tgcaatgtca accagatgat
    66181 cttcggtaac atcaaccagc agtttgaaac caatcagatg aatagtagga ttccattcct
    66241 tgactaggga tatgattttg ggtgtctttt taaggaacaa aacctgaacc tcatcagttg
    66301 aagaaatctt ggcctgatga ttctgcttgc ttaaaaattc ttttagattg gagctagcct
    66361 gaacttcctc aagccctgtc atataaacag gagtgtagtc agaaacagcc attgagtgga
    66421 tcaagacctg ataatcctga acacgttctt gcatttctat tagaaggtcc ttggtattgg
    66481 taatttctcg aatacttagg ttaggatgag gctctggctt cagagctcgt tttgtcgtaa
    66541 ttaaacaaac ttcatgccct gcagaaagca aagtctctgt gataattttc cccaagtgac
    66601 ctgtagaatg gttagtgata gagcggacgc tatcgatagc ttcactggta ccgcccgatg
    66661 taactaaaat tttcatagca ctattgtaca caaaaataag cggtaagtaa aatgaaagtg
    66721 ataaattttt ggtaaaaacg aagatttatt atagtttcaa actataaagc catataaaat
    66781 ttaagaaagg actctaaaag ccttaaaaac agagatattt acgaacgttt agagagtttt
    66841 aggatgttaa aaatcttgtt ttgtgatata atgaattatc atataagagg ttagaggaat
    66901 tttgaatgaa aacagatatt gaaatcgcac agagtattga gttgaagcca attgttgatg
    66961 ttgtagagaa acttggtatt tcttacgacg atttggagtt gtacggaaag tacaaggcta
    67021 aactcagctt tgataaaatt cgggcagttg agagcaatcc agtcggtaaa ttgatcttgg
    67081 ttactgccat caacccaaca cctgcaggtg aaggaaagtc tacgcttacc attggtcttg
    67141 cggatgcctt gaacaagatt ggcaagaaaa ccatgattgc tatccgcgaa ccgtctcttg
    67201 gtccagtcat ggggatcaag ggtggtgctg ctggtggtgg gtatgcacaa gttctgccaa
    67261 tggaagacat caacctccac tttactggag atatgcatgc tattacaact gccaacaatg
    67321 ccctttctgc cttgattgac aaccacttgc accaagggaa tgagctggga attgatcaac
    67381 gtcgtatcct ctggaaacgc gttgtggact tgaacgaccg tgcgctccgc catgtgactg
    67441 ttggtcttgg tggtcctcta aacggtattc cacgtgagga tggttttgat attacagttg
    67501 cttcagaaat catggcaatt ctttgcttgg caacggacat cgaggacttg aaacgtcgtt
    67561 tggcgaatat cgttattggt tatcgctatg accgtacgcc tgtttctgta ggtgatttgc
    67621 aggttgaggg tgccttggct ttgattttga aggatgctat taagccaaac ttggttcaga
    67681 caatttacgg tacacctgcc tttgtacacg gtggtccatt tgccaatatc gctcatggct
    67741 gtaactctgt tttggcgacg acaacagccc ttcacttggc tgattacact gttactgaag
    67801 ctggttttgg tgcggacctt ggtgctgaga aattccttga tatcaagaca ccaaacttgc
    67861 caacatctcc agatgcagtt gttattgtcg caacccttcg tgcccttaag atgaatggtg
    67921 gtgtggctaa agatgctctg actgaagaaa atgtagaggc agttcgtgca ggttttgcta
    67981 acttgaaacg ccacgttgaa aatatccgta agttcggtat tccagcagtt gtagctatta
    68041 acgaatttgt atctgataca gaagctgaaa ttgcagcctt aaaagaactc tgtgccttaa
    68101 tcgatgtacc agttgaattg gctagtgtct gggctgatgg agtagaaggt ggagtagaac
    68161 ttgccgaaac agttgttaag acaattgctg aaaatccagc taactataaa cgtttgtatg
    68221 ataatgacct ttctgtccaa gaaaagattg aaaaaattgt cactgaaatc tatcgtggta
    68281 gcaaagtgaa ctttgagaag aaagctcaaa cacaaattgc tcaagtcgtt caaaacggtt
    68341 gggacaaatt gccaatctgt atggctaaaa ctcaatacag tttctcagac aatccaaatg
    68401 cgcttggagc accagaaaac tttgaaatta ccattcgtga attggtacca aaattaggtg
    68461 caggcttcat cgttgcctta actggtgatg ttatgaccat gccaggtctt ccaaaacgtc
    68521 cagcagctct caacatggat gttgaaagcg atggaactgt actaggcttg ttctagtgga
    68581 ttgaaattga ctttaagtga gtttggaaat aatatccaag ctcatttttt ctcagactgc
    68641 aagcagttca tcaataagat ttatactctt cgaaaatctc ttcaaactac gtcagcttca
    68701 ccttgccgta ggtatatgat actgactctg tcagttctat ccacaacctc aaaacagtgt
    68761 tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga gtataagtag
    68821 atagaaaagt tatatactat ctattgaaaa tattataaat cagatacaaa gacaggtgaa
    68881 accttctgtg ttatactaga gatatgttag atttgaaaga atacggtatc gtcatgtggc
    68941 cggaggagaa agtcatttct ttccgtgaga aacttctcgc ttggtatgat gaaaacaaaa
    69001 gagatttgcc ttggaggaga agtaaaaatc cttatcacat ctgggtatct gaaatcatgc
    69061 ttcagcagac cagggtggat acagttatcc cttactacga aagattcctg gactggtttc
    69121 caactgtcga aagtctggca actgcgtctg aggagagttt actgaaagct tgggagggct
    69181 tgggctatta ttctcgagtt cgcaatatgc aggctgcagc ccagcagatt atgactgact
    69241 ttggtggcca atttccaaat acctatgaag gaatttccag cttgaaaggg attggacctt
    69301 acacagcagg agccatttcc agtattgctt ttaacttgcc tgagccagct gtagatggta
    69361 atgtcatgcg ggtcttggcg cgtctgtttg aagtcaacca cgatattggg attccaagta
    69421 atcgaaaaat ttttcaggca atgatggaga tcttgattaa tccggatcgt ccaggtgatt
    69481 ttaatcaagc cttgatggac ttagggtctg atattgagtc tcctgtaaat cccagacctg
    69541 aagaaagccc agtcaaggac tttagtgcgg catatcagaa tggaaccatg gaccgttatc
    69601 caattaaatc tcctaagaaa aagccggttc ctatttatct taaagcctta gttgtgaaaa
    69661 attctcaagg acaattttta cttgaaaaaa atgaaagcga aaagctcttg gcaggttttt
    69721 ggcatttccc ctttatagaa gttgataact tttcgcaaga agagcagttt gacctctttc
    69781 atcaggttgc ggaagaaagt gtgaactttg gtcccagtcc agaagagagt ttccagcagg
    69841 actatgacct agatgttgat tggcttgatg tttgttttga tacagtccag catgttttta
    69901 gtcatcgaaa atggcatgtg cagattgtag caggtcaggt gagtgacttc catgattttt
    69961 cagataggga agttcgctgg ctttcaccag aagaattcaa gaattaccca cttgccaaac
    70021 cccaacaaaa aatctggcag gcttatgcac aagccaactt agacagtagc caagactagc
    70081 tattgtgtct tctgactatt tttttggtat aatagtggag aaaaaggtga acatatgaaa
    70141 aaaatactaa ttgtagatga tgagaaacca atctcggata ttatcaagtt taatatgacc
    70201 aaggaaggtt acgaagttgt aactgctttt aatggtcgtg aagcgctaga gcaatttgaa
    70261 gcagagcaac cagatattat tattctggat ttgatgcttc cagaaattga tggtttagaa
    70321 gttgctaaga ccattcgtaa gacaagcagt gtgcccattc ttatgctttc agccaaagat
    70381 agtgaatttg ataaggttat cggtttggaa cttggggcag atgactatgt aacgaaaccc
    70441 ttctccaatc gtgagttgca ggcgcgtgtt aaagctcttc tgcgtcgttc tcaacctatg
    70501 ccagtagatg gtcaggaagc agatagtaaa cctcaaccta tccaaattgg ggatttagaa
    70561 attgttccag acgcctacgt ggctaaaaaa tatggcgaag aactagactt aacccatcgt
    70621 gaatttgagc ttttgtatca tttagcatcg catacaggtc aagtcatcac gcgcgaacac
    70681 ttgcttgaga ctgtctgggg ttatgactat tttggtgatg tccgtacagt tgatgtgact
    70741 gtacgacgtc tgcgtgagaa gattgaagat acgcccagcc gaccagagta tatcttgacg
    70801 cgccgtggtg tagggtatta catgagaaat aatgcttgat ttactgaaac aaaccatttt
    70861 taccagagat tttatcttta tcctgatttt gttaggtttc atccttgttg tgaccctctt
    70921 attactggaa aatagacgtg ataatattca gttgaagcaa atcaatcaaa aggttaaaga
    70981 tttgattgca ggagattatt ccaaggttct tgatatgcaa ggtgggtctg aaatcaccaa
    71041 tattaccaat aatttgaatg acttgtcgga ggttattcgt ctcactcagg aaaatctaga
    71101 acaagagagt aagaggctaa atagtattct gttttatatg acagatgggg ttcttgcgac
    71161 caaccgtcgg ggtcagatta tcatgattaa tgatacagcc aagaagcaac tggggttggt
    71221 taaggaagat gttctgaata gaagcatttt ggaattgctc aagatagaag aaaactatga
    71281 attgcgtgat ttgattaccc aaagtccaga attgttgcta gattcccaag atatcaatgg
    71341 cgaatatttg aaccttcgag ttcgctttgc cttgatacgt cgagagtctg gctttatttc
    71401 aggtttggtg gctgttttgc atgatacgac ggagcaggag aaggaagaac gagaacgaag
    71461 actctttgtt tccaatgtta gccatgagtt acggactcct ctgactagcg taaaatccta
    71521 tcttgaagcc ttggatgagg gggctttgtg tgaaactgta gcaccagact ttatcaaggt
    71581 ttctcttgat gagaccaacc gtatgatgcg catggtgacg gatctcctcc atctttcacg
    71641 tattgataat gctaccagtc tcctagatgt ggaactgatt aacttcactg cttttattac
    71701 ctttatcctc aatcgttttg acaagatgaa aggacaggaa aaggagaaaa aatatgagtt
    71761 ggtgagagat tatcccatca attctatctg gatggaaatt gatacagata agatgacgca
    71821 ggttgtcgac aatattttaa ataatgctat taagtattcg ccagatgggg gtaaaatcac
    71881 tgtcagaatg aagacaactg aagaccagat gattttatcc atttctgacc acggtttggg
    71941 gattcctaag caggatttac cacgtatctt tgaccgtttc tatcgtgtgg atcgtgctag
    72001 aagtcgtgca caaggtggta caggtctagg actgtctatc gctaaagaaa ttatcaaaca
    72061 acataagggc tttatttggg ccaagagtga atacggcaag ggttcaacct ttaccattgt
    72121 gctcccttat gataaggatg cagtgaaaga agaagtatgg gaggatgaag tagaagacta
    72181 gaatgagtga aataggcttt aaatacagta ttttagcgtc gggttccagt ggaaattctt
    72241 tttatctgga aacctcaaaa aagaagcttt tagtggatgc aggcttgtct ggcaagaaaa
    72301 ttaccagtct gctagctgaa attaaccgca agccagaaga cctggatgcc atcttgatta
    72361 cccatgagca ttcagatcat atccatggag taggcgtttt ggctcgcaag tatggtatgg
    72421 atctttatgc caatgaaaag acctggcaag ctatggaaaa tagtaaatat cttggcaagg
    72481 tggattcttc gcaaaagcat atttttgaaa tgggtaaaac caaaactttt ggagatatcg
    72541 acatcgagag ttttggtgta agccatgatg cagtcgcacc gcagttctat cgctttatga
    72601 aggatgacaa gagttttgtc cttttgacag atacaggtta tgtcagtgac cgtatggcgg
    72661 gcattgtcga aaatgcggat ggctatctta tcgaggccaa ccatgatgta gagattttgc
    72721 gatcaggttc ttacgcttgg cgactcaaac aacgaatcct atctgacctt ggtcaccttt
    72781 ctaacgagga cggtgctgaa gctatgattc ggacgctagg aaatcgtact aagaagattt
    72841 accttgggca tttatctaag gaaaacaata tcaaggaact ggctcatatg accatggtca
    72901 atcagctggc tcaagctgat ctgggagtcg gagtagactt taaggtttat gatacctcac
    72961 cagataccgc aacaccattg acagagatat agaaagaacg ctgagaaggt gttcttttta
//
LOCUS       DBEJZV010000008        58674 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.08, whole genome shotgun sequence.
ACCESSION   DBEJZV010000008 DBEJZV010000000
VERSION     DBEJZV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 58674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.08"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            207..483
                     /locus_tag="ACL3S0_000628"
                     /pseudo
     CDS             207..483
                     /locus_tag="ACL3S0_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(608..736)
                     /locus_tag="ACL3S0_000629"
                     /pseudo
     CDS             complement(608..736)
                     /locus_tag="ACL3S0_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294374.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(804..1886)
                     /locus_tag="ACL3S0_000630"
     CDS             complement(804..1886)
                     /locus_tag="ACL3S0_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR1311586.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2012..2794)
                     /gene="gatD"
                     /locus_tag="ACL3S0_000631"
     CDS             complement(2012..2794)
                     /gene="gatD"
                     /locus_tag="ACL3S0_000631"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGR1311587.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2794..4137)
                     /gene="murT"
                     /locus_tag="ACL3S0_000632"
     CDS             complement(2794..4137)
                     /gene="murT"
                     /locus_tag="ACL3S0_000632"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGR1311588.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4236..5552)
                     /locus_tag="ACL3S0_000633"
     CDS             complement(4236..5552)
                     /locus_tag="ACL3S0_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGR1311589.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVTAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5745..6971
                     /locus_tag="ACL3S0_000634"
     CDS             5745..6971
                     /locus_tag="ACL3S0_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGR1311590.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKALT"
     gene            7170..8744
                     /locus_tag="ACL3S0_000635"
     CDS             7170..8744
                     /locus_tag="ACL3S0_000635"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR1311591.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9008..9796
                     /gene="codY"
                     /locus_tag="ACL3S0_000636"
     CDS             9008..9796
                     /gene="codY"
                     /locus_tag="ACL3S0_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGR1311592.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9796..10371
                     /locus_tag="ACL3S0_000637"
     CDS             9796..10371
                     /locus_tag="ACL3S0_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR1311593.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10453..10538
                     /locus_tag="ACL3S0_000638"
     tRNA            10453..10538
                     /locus_tag="ACL3S0_000638"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10487..10489,aa:Leu,seq:aag)
     gene            10821..11951
                     /locus_tag="ACL3S0_000639"
     CDS             10821..11951
                     /locus_tag="ACL3S0_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311594.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12452..13210
                     /locus_tag="ACL3S0_000640"
     CDS             12452..13210
                     /locus_tag="ACL3S0_000640"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR1311595.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13298..13810
                     /locus_tag="ACL3S0_000641"
     CDS             13298..13810
                     /locus_tag="ACL3S0_000641"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGR1311596.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13992..14936
                     /gene="metA"
                     /locus_tag="ACL3S0_000642"
     CDS             13992..14936
                     /gene="metA"
                     /locus_tag="ACL3S0_000642"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGR1311597.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14945..15622
                     /locus_tag="ACL3S0_000643"
     CDS             14945..15622
                     /locus_tag="ACL3S0_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR1311598.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTSQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15720..16478
                     /gene="tpiA"
                     /locus_tag="ACL3S0_000644"
     CDS             15720..16478
                     /gene="tpiA"
                     /locus_tag="ACL3S0_000644"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGR1311599.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16516..18021
                     /gene="lytC"
                     /locus_tag="ACL3S0_000645"
     CDS             16516..18021
                     /gene="lytC"
                     /locus_tag="ACL3S0_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGR1311600.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELKRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18519..19037
                     /locus_tag="ACL3S0_000646"
     CDS             18519..19037
                     /locus_tag="ACL3S0_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGR1311601.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            19167..19673
                     /locus_tag="ACL3S0_000647"
     CDS             19167..19673
                     /locus_tag="ACL3S0_000647"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGR1311602.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19673..19843
                     /locus_tag="ACL3S0_000648"
     CDS             19673..19843
                     /locus_tag="ACL3S0_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311603.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            19875..21107
                     /gene="clpX"
                     /locus_tag="ACL3S0_000649"
     CDS             19875..21107
                     /gene="clpX"
                     /locus_tag="ACL3S0_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGR1311604.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRMGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21116..21703
                     /gene="yihA"
                     /locus_tag="ACL3S0_000650"
     CDS             21116..21703
                     /gene="yihA"
                     /locus_tag="ACL3S0_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGR1311605.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21714..22094
                     /locus_tag="ACL3S0_000651"
     CDS             21714..22094
                     /locus_tag="ACL3S0_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGR1311606.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22146..23036
                     /gene="rapZ"
                     /locus_tag="ACL3S0_000652"
     CDS             22146..23036
                     /gene="rapZ"
                     /locus_tag="ACL3S0_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGR1311607.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            23033..24010
                     /locus_tag="ACL3S0_000653"
     CDS             23033..24010
                     /locus_tag="ACL3S0_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGR1311608.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            24007..24918
                     /gene="whiA"
                     /locus_tag="ACL3S0_000654"
     CDS             24007..24918
                     /gene="whiA"
                     /locus_tag="ACL3S0_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGR1311609.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(25006..26133)
                     /locus_tag="ACL3S0_000655"
     CDS             complement(25006..26133)
                     /locus_tag="ACL3S0_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR1311610.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSMMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(26275..26655)
                     /locus_tag="ACL3S0_000656"
     CDS             complement(26275..26655)
                     /locus_tag="ACL3S0_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGR1311611.1"
                     /translation="MTIEELVDSHGVTLAYFDNELWQRPGVYIKEISIIFINRELSED
                     AKKRVIYHELGHLEHSTALYQNNHTRCENEANRHMIHKLLEEELALSDDHQSFNYIQF
                     MQKHKLRTVTDELMVIDEYYELIG"
     gene            complement(26878..27972)
                     /locus_tag="ACL3S0_000657"
     CDS             complement(26878..27972)
                     /locus_tag="ACL3S0_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311612.1"
                     /translation="MTITEQDALLFNTLFENIYHQLPSVDSSKDYWFVRAQKGQFYKS
                     FQTGGYIAIGWNYITLDDLKNLDEDAIKGKIKEFDSRIEKPGSAYNQMMKFAYSLKIG
                     DIVIVPSESPNDFLVGEITSRPYTESESNIESASNVCPFNKRMNVHWFGVIPNRDIDP
                     KLYKLVYSGHTITDANAYKKFINRGLYDAYIDHDHMSITFKVQEENNIDAFEYSTFLH
                     TVLQMVNVVKESDELKDEKVVLRTNVQSKGPIELLGHPEILIPVLVFIIILTGGIAFR
                     NLIKRNGANFEVDSKLGKFKAQLNSDGDEAIKKAQANKINAEAIALLIDKGMSPQFKG
                     ATSQLDIKAPEVATRILQDELLESPEKVEE"
     gene            complement(27974..28327)
                     /locus_tag="ACL3S0_000658"
     CDS             complement(27974..28327)
                     /locus_tag="ACL3S0_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1311613.1"
                     /translation="MFSTLEKIKELAKKRGIPLTKLEESLGYSTNYFYTLKTKTPNSE
                     RLQQIADYFNVSTDYLLGRTDNPAIAGDDTISGYTSDDLRKMAENAKTFDGKPLTEED
                     IDAIQNIIEIYLRGR"
     gene            complement(28725..28817)
                     /locus_tag="ACL3S0_000659"
     CDS             complement(28725..28817)
                     /locus_tag="ACL3S0_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGR1311614.1"
                     /translation="MMELILKTIIGPIVVGVVLRLADKWLNKDK"
     gene            complement(29040..29129)
                     /locus_tag="ACL3S0_000660"
     CDS             complement(29040..29129)
                     /locus_tag="ACL3S0_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I addiction module toxin, Fst family"
                     /protein_id="HGR1311615.1"
                     /translation="MVDYIFTNIILPLVVGIVLIVIEKWLNKK"
     gene            complement(29353..29592)
                     /locus_tag="ACL3S0_000661"
     CDS             complement(29353..29592)
                     /locus_tag="ACL3S0_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311616.1"
                     /translation="MTFKEYLLKASKRDIYDDGKDFDFETIFAREILRYAHDSELETK
                     TGFFRHLEIMNADSWFVELARSIYQDFEKSISDSH"
     gene            29657..29848
                     /locus_tag="ACL3S0_000662"
     CDS             29657..29848
                     /locus_tag="ACL3S0_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGR1311617.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            complement(30031..30222)
                     /locus_tag="ACL3S0_000663"
     CDS             complement(30031..30222)
                     /locus_tag="ACL3S0_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311618.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTVELLEKYHEWLHS"
     gene            30563..30835
                     /locus_tag="ACL3S0_000664"
     CDS             30563..30835
                     /locus_tag="ACL3S0_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311619.1"
                     /translation="MEVVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            30832..31026
                     /locus_tag="ACL3S0_000665"
     CDS             30832..31026
                     /locus_tag="ACL3S0_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311620.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            31023..31214
                     /locus_tag="ACL3S0_000666"
     CDS             31023..31214
                     /locus_tag="ACL3S0_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311621.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            31226..31567
                     /locus_tag="ACL3S0_000667"
     CDS             31226..31567
                     /locus_tag="ACL3S0_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311622.1"
                     /translation="MTQAEQIREYYREHPAASCDEVAEVVGTTKSNVSANLAKDIKAG
                     RCVRLEDKSYDYSPYFNHTQALTELVDWKNDTRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            31568..31798
                     /locus_tag="ACL3S0_000668"
     CDS             31568..31798
                     /locus_tag="ACL3S0_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311623.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            31812..32534
                     /locus_tag="ACL3S0_000669"
     CDS             31812..32534
                     /locus_tag="ACL3S0_000669"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HGR1311624.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGVSLTEKQIKSYRRNNNLHSGLTG
                     RFEKDQTPHNKGKKYPNMPKNSGQFKKGNRPPNYVPVGTINYTTDGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            32527..33009
                     /locus_tag="ACL3S0_000670"
     CDS             32527..33009
                     /locus_tag="ACL3S0_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HGR1311625.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQAAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNENDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELIRTEKLVIK
                     "
     gene            33018..33368
                     /locus_tag="ACL3S0_000671"
     CDS             33018..33368
                     /locus_tag="ACL3S0_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311626.1"
                     /translation="MNKTRVTDSLAVVIGLESIEVLVTEGFLFDVAIRFVKVDETNLD
                     QGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQNWFN
                     TALYPGVLTEKVGV"
     gene            33368..33853
                     /locus_tag="ACL3S0_000672"
     CDS             33368..33853
                     /locus_tag="ACL3S0_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311627.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNEKSKDNSVAETIAYIQLCYPEAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            33816..35009
                     /locus_tag="ACL3S0_000673"
     CDS             33816..35009
                     /locus_tag="ACL3S0_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR1311628.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            35028..35345
                     /locus_tag="ACL3S0_000674"
     CDS             35028..35345
                     /locus_tag="ACL3S0_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311629.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            35345..36121
                     /locus_tag="ACL3S0_000675"
     CDS             35345..36121
                     /locus_tag="ACL3S0_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR1311630.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYVNH
                     VDDKAILKILATIRGAVEPAKTEKTKEAPKKEVASDDELF"
     gene            36141..36644
                     /locus_tag="ACL3S0_000676"
     CDS             36141..36644
                     /locus_tag="ACL3S0_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311631.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKDLNWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALKRKAVGSYYNLVISVTKGKDGREFRNYDLEEEAQPLTEADI
                     DDDDLPF"
     gene            36817..37638
                     /locus_tag="ACL3S0_000677"
     CDS             36817..37638
                     /locus_tag="ACL3S0_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HGR1311632.1"
                     /translation="MSSMKEYALQYQKLGFSVIPINPKNKMPLIDFADKPAMTPSEIE
                     NFWDGYPNANIALKITNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKDLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            37641..38984
                     /locus_tag="ACL3S0_000678"
     CDS             37641..38984
                     /locus_tag="ACL3S0_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HGR1311633.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERATEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQKEYLKDKTGER
                     RFLPIMADSKQQKKHPMEIDPDTIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKNTKGFVRVKNSEKTNR"
     gene            39277..39429
                     /locus_tag="ACL3S0_000679"
     CDS             39277..39429
                     /locus_tag="ACL3S0_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311634.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KMEEME"
     gene            39429..39767
                     /locus_tag="ACL3S0_000680"
     CDS             39429..39767
                     /locus_tag="ACL3S0_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311635.1"
                     /translation="MSYDLEILAKIESGDYICIAEPRYSSPTYNLGKMFRVAMDWDFD
                     QGTIYNVADIFENIKRGITELERQPEKYVQYEPANKWGTINDALYVLRSLRDCILEQD
                     IDTKYLYVRW"
     gene            39918..40232
                     /locus_tag="ACL3S0_000681"
     CDS             39918..40232
                     /locus_tag="ACL3S0_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311636.1"
                     /translation="MEELKRKVNTVYNWTVEDGKPQPPKQDLPQVVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGATKDWLPKSKEFDDWVGYSPSMAQVVIAVYLIYR
                     GN"
     gene            40234..40761
                     /locus_tag="ACL3S0_000682"
     CDS             40234..40761
                     /locus_tag="ACL3S0_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HGR1311637.1"
                     /translation="MNKQELIKKLEERRTITGNFQGYVVWWKDVKEIFEQLGEPQPVK
                     VPQFVADWIRKCKMFKHFAVSLSFALQPIVWEENGLSHECIEWLMDANNQELFALAWL
                     NGYEVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELEDANF
                     GWVFDCEGIDIEEVE"
     gene            40823..41140
                     /locus_tag="ACL3S0_000683"
     CDS             40823..41140
                     /locus_tag="ACL3S0_000683"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGR1311638.1"
                     /translation="MRYFKILCIVLFASLLVACHQISSGTVVDKYIDEPHTTFIPVIN
                     GKSSVLVPTRTKRKYILVVSGYAGNKQVEERFEVTANEYKHYEIGNTFIQDAVLENKE
                     EDK"
     gene            41258..41680
                     /locus_tag="ACL3S0_000684"
     CDS             41258..41680
                     /locus_tag="ACL3S0_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HGR1311639.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWIDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRLINKLKNPKSRSILRVTYITK
                     MYVDDICDKMEISRTTFYTWRNMAISELNEVLERMELN"
     gene            41766..41848
                     /locus_tag="ACL3S0_000685"
     tRNA            41766..41848
                     /locus_tag="ACL3S0_000685"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41797..41799,aa:Tyr,seq:gta)
     gene            42950..43462
                     /locus_tag="ACL3S0_000686"
     CDS             42950..43462
                     /locus_tag="ACL3S0_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0051276 - chromosome organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HGR1311640.1"
                     /translation="MAFFDCLKGGDGKLNERQRRFADEYIISGNAYQSALRAGYSEKY
                     AKARSSELLDNVGISDYIKNRMEELQDEKILTQKQILVMLSEIASGQAKETIVVTTKV
                     AELMTDPVTGKSVKVYNEIPQLVEYPTKNSDRNKALELLGKRHKMWTDKVEADVSGTV
                     VFANESDISD"
     gene            43440..44738
                     /locus_tag="ACL3S0_000687"
     CDS             43440..44738
                     /locus_tag="ACL3S0_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HGR1311641.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETSRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIVADSAELRL
                     IEELRSEHGITRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            44750..46219
                     /locus_tag="ACL3S0_000688"
     CDS             44750..46219
                     /locus_tag="ACL3S0_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046798 - viral portal complex [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0051027 - DNA transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGR1311642.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHNTESSRLKNLKSYYM
                     GDHAILNHKRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADSDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKYQAEVFTENLHYHMVLRSTDSGTTQNEQVTPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            46128..47765
                     /locus_tag="ACL3S0_000689"
     CDS             46128..47765
                     /locus_tag="ACL3S0_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HGR1311643.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPESEIKHLQSFSWVGDGSTYSTDIWKNTGKLTSSIKDELLMSLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVAYDEDADYSKLKRRARNPVTGKTELVPADM
                     TYKEWYSKYVAKDGEKVYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRIAGENKL
                     AGLEFRKKTVESLSRKIIADSLVENISLSKAVSKINDALRYTTIFDSDTFTEEYLKMK
                     QKLVAEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNGSLHELY
                     EKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            47767..47976
                     /locus_tag="ACL3S0_000690"
     CDS             47767..47976
                     /locus_tag="ACL3S0_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311644.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSIDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            47973..48386
                     /locus_tag="ACL3S0_000691"
     CDS             47973..48386
                     /locus_tag="ACL3S0_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGR1311645.1"
                     /translation="MIDIALAIAKKAHAGQVDKADVDYIQHPLYVASQVKTEQEKAVA
                     LLHDVIEDSDITAADLLASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIYYLST"
     gene            48428..48601
                     /locus_tag="ACL3S0_000692"
     CDS             48428..48601
                     /locus_tag="ACL3S0_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311646.1"
                     /translation="MDKAKIGITNVEFSGTGGIESATVKLELNIYGADTFSAIELLPK
                     ILTDIHSLSYEVD"
     gene            48868..49392
                     /locus_tag="ACL3S0_000693"
     CDS             48868..49392
                     /locus_tag="ACL3S0_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HGR1311647.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTNAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQT
                     VQQEVTEKWRKDFL"
     gene            49415..50440
                     /locus_tag="ACL3S0_000694"
     CDS             49415..50440
                     /locus_tag="ACL3S0_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-binding protein"
                     /protein_id="HGR1311648.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFSAALGNVSDNVTMGKEAGANNAYNAILDVSEKLDEL
                     GITKERLLFVTPKFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKKSAQGKTVNRAKAWKTGTAYKEGDTVTHEDKVYVAIKDITSSTNAPGSDSANW
                     KEKTGKK"
     gene            50450..50638
                     /locus_tag="ACL3S0_000695"
     CDS             50450..50638
                     /locus_tag="ACL3S0_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311649.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVA
                     ISDVLEKILPEPEFLEED"
     gene            50640..50951
                     /locus_tag="ACL3S0_000696"
     CDS             50640..50951
                     /locus_tag="ACL3S0_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HGR1311650.1"
                     /translation="MSIELLKKLTGEEDTQLLMLFQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            50932..51270
                     /locus_tag="ACL3S0_000697"
     CDS             50932..51270
                     /locus_tag="ACL3S0_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311651.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            51245..51760
                     /locus_tag="ACL3S0_000698"
     CDS             51245..51760
                     /locus_tag="ACL3S0_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HGR1311652.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELIISIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQANHSGISPEV
                     SVTYKSNPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            51757..52125
                     /locus_tag="ACL3S0_000699"
     CDS             51757..52125
                     /locus_tag="ACL3S0_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311653.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            52128..52541
                     /locus_tag="ACL3S0_000700"
     CDS             52128..52541
                     /locus_tag="ACL3S0_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HGR1311654.1"
                     /translation="MLANGIKLAFSETKGNYQNLVGLKEVPEFGIEPEKVENTTLADT
                     VKKYEFGIGDAGELEYKFAYNNSSATAPYRVLRKAADGKKKLYFEQTYPDGTKVTFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSELTFVDGIGG"
     gene            52546..52926
                     /locus_tag="ACL3S0_000701"
     CDS             52546..52926
                     /locus_tag="ACL3S0_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6096 family protein"
                     /protein_id="HGR1311655.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVVE"
     gene            52965..53315
                     /locus_tag="ACL3S0_000702"
     CDS             52965..53315
                     /locus_tag="ACL3S0_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311656.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYI
                     LSRMITNHVSLLLSNDAKIVELWEYAPELFVEEQQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEVNGNS"
     gene            53302..56895
                     /locus_tag="ACL3S0_000703"
     CDS             53302..56895
                     /locus_tag="ACL3S0_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311657.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGNTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSIATIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLAYAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFAETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIGNIFGNLGSWFGGRWNDSKNALAEANTWLGDKFKS
                     GRDKVNSAFEKVGSWFGDRWNDIKDGVKEADTWFGEKFESAKKKTQNPFQKIGSWFGD
                     RWKDMQDALKEIPNWFKNLFNDAMDNAKNIVKSGIDKLKSFFNFDWSLPKIKLPHFNI
                     SGSFSLMPPRIPSFSVDWYARGGVFNSPSIIGVGEAGQEAVMPLERNTGWISILAQKL
                     AERMPANNVPTGYSLPAGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI"
     gene            56904..57254
                     /locus_tag="ACL3S0_000704"
     CDS             56904..57254
                     /locus_tag="ACL3S0_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6711 family protein"
                     /protein_id="HGR1311658.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGARTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            57259..>58674
                     /locus_tag="ACL3S0_000705"
     CDS             57259..>58674
                     /locus_tag="ACL3S0_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HGR1311659.1"
                     /translation="MDALTRRQFDRSMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKHIKQQGGIEAKIQAQIEATDKDFDQKVDKIKKDFNDQVELAKAKAEEVKRE
                     LSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIAND"
BASE COUNT        18559 a        10320 c        13157 g        16638 t
ORIGIN      
        1 caagagggag agtacctgag agcggagaat gccatcctaa aaaagttaag agaactccga
       61 ttgaaggagg aaaaagagaa agaagaaaga cagaaattgt tcaagaatta atgactgagt
      121 tttcgttagt tcttcttcta aaagccatta aactagctcg ttggacctac tactatcact
      181 tgaaacagct agacaaaaca gataaggacc aaggctggca atatcaacac gattcttatc
      241 atcggtttct agagagtaag ggaattcaag catccatgtc acgtaagggc aacagcccag
      301 acaacggtat gatggagtcc ttctttggga ttctgaaatc ggaaatgttt taagtcgttt
      361 cagtcgctta agcaattgga acaagctatt gtagactata ttgattacta caacaacaaa
      421 cgaattaagg taaaactaaa aggacttagt cctgtgcagt acagaactaa atccttcgga
      481 taaattaatt gtctaactgt ttggggtcag tacacaatac ctgatagtat gcgttttatt
      541 gtgggaagat tttcctcatt ttctagtgaa attgaacttt ttctaacatc ttttgataga
      601 tgacttctta atcaattatc atttccattg ttgtttcttg gggtttcatc ccttgtcttt
      661 gataaaagcg gagagcaccc tcgttatcat tccagacact tagggttaga ttattgtagc
      721 caatttcttt agcataatag cagaaaaatg acaataaaat agcccctaga tattttgaaa
      781 ggaaagcata ggggctatat ggtttaatca aaataaagca aatctttgct ggtgcttgta
      841 aagaggtcga agccatcctt ggtaacaaca ccgcagtctt caatacgaac accgacttta
      901 ccagggatat agatacctgg ttcaacagag aagcacatgc cttcttcgat gaccatgtcg
      961 tttccttcca tgatagatgg gaattcatgg acatccatac cgataccatg cccgagacgg
     1021 tggttgaagt actcaccata accagctttt tcgatgacct cacgggcagc gcggtccact
     1081 tcatgagcag tcacacctgg cttgataaag tcaagagcag cttgttgggc ttcaagagtc
     1141 aagttgtaaa tatctttctt gaattggtct ggtttgccga cagcgactgt acgagtcata
     1201 tctgacgcat agccattgac cagaacaccc aggtcaaaga ggagaagagc atcattttca
     1261 accttattag ctgctggaat gccgtgtgga ttcgcagcat tatcaccagt caagaccatg
     1321 gtatcaaagc tcatttcgta accttcacgt ttcatggcaa agtcaatttg tgcgatgata
     1381 tctgtctcag tcttatcaag agaaatatta tcaaaaccaa catgaacagc cttgtcagca
     1441 taaagacctg caaccatcat tttttgcact tcatcagctg atttgatgag gcgcatgcgt
     1501 tggatacgag gagtgaggtt gtcaaactca gcagtctcaa aaactgtttt caaaccatgg
     1561 tatttggtca agatgagatt gtcaaactca acagcgacac gtttgaagtc aagttgtgga
     1621 agagcatgtt tgattttttg ccatggattt tcagaatcga catagcccac tactgggaag
     1681 gaaacggtgc tacttgcacg ttctacttca agagctggga caaagaggag aggttcctga
     1741 tccgctagga caaagaggaa catttggcgt tcatggggat cactgtaaaa accagtgagg
     1801 taattgattg tgacggggtc agatacgaca gcgacgtcta gtttttctga ttcaagatat
     1861 gttaggattt gttgtaattt agacatatgc taccttcttt ctacccctct attttggcaa
     1921 aaaatgagag aaaatgcaag ggagaagggt aaaagaaaag acaaaaaact ccgacaagat
     1981 aacggagttc tttgatatca ttttcctttg tttaagaaaa gtcagccttg cttttgacgt
     2041 cactgtactc ttcagcgatt tcttggctga ggatatcctc ataggcaggg agttggatat
     2101 cctgaccata tttcttcttg agggcagtag taactaggcg ataagccaga ttggcattac
     2161 gagagaggat aggtccgtgg aagtaggaac caaagacatt cttataatga accccttcac
     2221 cgaccttttc ttcgttgttt ccatttccat agacaacctg tcccagcggt ttttggtcat
     2281 cagagaggaa ggtacgacct tggtgatttt caaatccata gtaggtttca tcgaaatctt
     2341 cattgtgaat cttgatgtca ccgataaaac ggttattggt ctggttgagc gtgtagtgtc
     2401 ccatgacccc tagcccttcg atacgttttc ctgaagcttc aacataatat tgacccaata
     2461 gttggaaacc accgcagata gccagaacta caccgtcgtt ttggatgtag ttgtcaatgc
     2521 tctctttttt agcaggtagg tcgtctgcaa tgatactttg ttcaaagtct tgaccaccac
     2581 cgaaaaaggc gatgtcgtag tgattttcat caaagtcatc atggagagaa acgatgtcaa
     2641 cggtcacatg ggctcccagt ttttcagcca catacttgag catgaggatg tttccattgt
     2701 ccccgtaggt attcatgaga tttccgtaga ggtgggcaat gttgagctga taggggtaat
     2761 tgccatcttt tgaggaaagt gaagtataaa ccattagttc atctcctttc taacaatctg
     2821 acgactagcc agcagttcac gaaattccag catggcagta taagttgcca gaatataggc
     2881 atgcttgcag tcttgattct caatggtctt gagaacttgc tccagattac tcgtttcagt
     2941 gattttctca gctggatagc cagtcactcg gaggcgacga gcgatttcag aatgacgaac
     3001 accgccagcg ttgatttcag gaatgtccat gtcagtgatt tgttcaaagt ctgcatccca
     3061 gatccagcta gtgtcaattc catctgcata gttggcatta aggaggacag ataggctaaa
     3121 tggataaggt gctagtttga tcatttcgat agcttgggtt gcaccgactg gatttttaat
     3181 caagacaagg gtacattcct tgtcaccgat atgaaaggtt tcttggcgtc caaagacagc
     3241 acggctcttg tcaaatccct gtttgatgag ttgcgaatcg gcacctagga aacgggcgat
     3301 ggccacagca gctagggcgt tatagatatt atagagcccg ccgatttgga taccgtattc
     3361 ttggccgtct atgacaaagc gagagcgatt gttggtcaac tcaaccagtt ttgtcaaacg
     3421 atagtcgaga tcaggacgtt tgcatccaca accttcacag atataggcac ccaagtttgc
     3481 ataggtatta tgctcatatt tgaggatgcc ttggcagtca ggacagagaa tcccttcggt
     3541 attgtagtga gccagttggg ctggtccttt ttccaagtca aaaccaaaat actctatagg
     3601 gtttggaata gttggcttgt agaaaagtgg actgtctccg ttaaggagaa cagtagcagt
     3661 tggaactttc cgaatggcat ccaatatcat gttataggta gtatagattt caccgaaacg
     3721 gtccatctgg tcacggaaga tattagtaat gacaaaaaga ctaggctgga tatagtcaca
     3781 gatacgagat agactggctt cgtcaatttc gaggacggca atatttttcc cagtttttga
     3841 agatttggct gttaggaagg ttgttgcaat ccctgtaatc atgttggcac cgcttgggtt
     3901 ggttagaact tgaccataaa cctcttttaa aatgccgaca gtgagggcag ttgtcagggt
     3961 ttttccattt gttccagtga caacgacaat ctcgtagttc ttagctaggt tttgtaaaat
     4021 atctttatca aattgaaggg cgactttacc tgggagcgta cttccacggc caagacggct
     4081 taaaatgaag tgggaagaac gcccagcaag aaggcccaaa gtagttttta agttcatgtt
     4141 tctattatat cataaaagag gagaaagaca gatttgagat tccgcagaag taaaaacagc
     4201 ccaaagaggg ctgttcgata cgattaaatc tcaacttaaa tcgcaaacaa gtcattcaag
     4261 ttctcagcca aggttgggtg agtgaagatt tgttttgtga agtaagtgta aggaatcttg
     4321 ttgtccatag caacagtgat gatgttgatg atttcttgag aaccttctga gaagatgctt
     4381 gctccaagaa tttcttttgt ttcagtattg acaacagctt tgaaggcacc gcgaaggtct
     4441 ccatttacgt gaccacgagg cattgctgta acggggattt ccttaacagc gtatggaagt
     4501 ttcaaatcag ctgcttggct ttcagtcaaa ccaacttgtg aaagtgcagg tgtgatgaac
     4561 atagtatttg gcacattgag acggtcttca agtgtgtagc tgccatctcc agcaaggtag
     4621 ctgtaaacaa cacggaagtc atcaagtgaa atgtaagtaa attgaaggcc accgttgaca
     4681 tctccaactg caaagacacc aggaacgttt gtttgacagt gtttgtctac tttaatagca
     4741 ccacgttcag ttagttcaat atctgtattt tcaagttgaa gtggttctac atttggtttg
     4801 cgtccagttg cgtagagaag ggcgtcgaaa cggtaagttt cgtcttcagt tacgacaagc
     4861 acttggtcac catcgttttt gatttcagta gtatggatat tttgaagcaa ttcaatgcca
     4921 tcttcttcca tgtattgttt agcaagagct gcgatggaag gttctgcacg aggtaggaat
     4981 gtatccaagg catctaggac tgtgaccttg cttccaagtt tgttgtaaag gccggcaaat
     5041 tcaagaccga tatttccgcc accaaggatt ccaagttttt caggtaattt gtccaagctt
     5101 tggatacctg ttgagtcaaa gatgtttttg cttgtagcaa gtccagggat tggcaagacg
     5161 tttgaaacag caccagtgtt gatgacgatt gtttcagcag tcagttcttt cttttcatca
     5221 ccagcttgga tttcgatgac tttatttgaa aggaagtgag cttccgcatc aaagatatct
     5281 acgcctgtac cagcaacagt cgcatagttt ttaccgttga ggcgaccagt gatcgtgttt
     5341 ttagtagcaa tgacttcttc aaaagacaag tccttttcag cagcaactag caaggtttta
     5401 gttgggatac aaccaatgtt gatacaagtt ccaccgtaca tagccttgct gcgttcaacg
     5461 agggcaactt ttttgccagc tgaagccaat ttacctgcta gtgttttacc agctttacca
     5521 aatccaataa caattaaatc gtatgttaac atttatcttc ctcctattcg aatttcattc
     5581 tagcacaaga aaaaaacttt tgcacaattc tgctacggaa aagacagaaa aagataaaaa
     5641 cgctttccag acaaaaaact agtaattttt tgacaagctt gataaactaa aatcctatct
     5701 atttttatat aagatagaat aaatgttcga aaataggagg ttttatgaaa tcgaatcgtt
     5761 atattattgc ctttgctggg gtcattttac acttaatgct gggttcgact tatgcttgga
     5821 gtgtttatcg taaccctatt attgaaaaaa cgggatggga tcaggcttct gttgccttcg
     5881 cctttagtct agcaatcttt tgtttgggct tatcggctgc atttatgggg cgtttggtag
     5941 aaaaatttgg tccgaaagtc atgggaagtc tatctgcttt tctatacgca ggtggaaata
     6001 tcttaacagg atttgcaata gaccgtcagg agctgtggtt gttgtatctc gcttatggca
     6061 ttttaggtgg gcttggtttg ggagcaggct atattacccc tgtgtcgacg attataaaat
     6121 ggtttcctga taaacgtggt ctcgcaacag gtttagcgat tatggggttt ggttttgctt
     6181 ctttattgac tagtcccata gcgcaacacc tcatcgcagg ggtagggctt gtagaaactt
     6241 tttatatttt aggagcaagt tactttatta tcatgctcct agcttcacaa ttcattaagc
     6301 gtccaaatga gcaagagctt gcaattttat cttcttcagg gaaagaaaaa acagcctctt
     6361 tgacgcaagg aatggctgca aatcaggctc taaaaagcaa tcggttttat atgctttgga
     6421 ttattttctt tatcaacata gcttgtggtt taggcttaat ttcagcggca tcgccaatgg
     6481 cacaggagat ggctggcttg tctacaagtc atgcagcagt aatggtgggt gttttgggga
     6541 ttttcaatgg atttggtcgc ttgctctggg cgagtttgtc tgactatatc ggtcgccctc
     6601 taacctttag tatattactg cttgtcaatc ttttcttttc tctctcactt tggctcttta
     6661 cagattccgt tttatttgta gttgctatgt ctattttgat gacttgctat ggagctggtt
     6721 tttctttgat tccagcttat ctcagtgata tttttggaac caaggaattg gccgctctgc
     6781 atggttatat tttaacagct tgggcaatgg ctggtttagc gggacctatt ttattagcag
     6841 agacttataa aatggctcat tcgtacacac aaaccttgtt cgtttttctc attttataca
     6901 gtatcgcctt ggctttgtct tattatctag gtcgttcaat caaaaaagaa agtcaaaaag
     6961 cgcttacatg attttctgta gaaatggggc tatcttttgc tctggtcttg tgttatacta
     7021 gataggttgc aaagaaaaca gtacttttct tttgtggaaa agaagcaaca cgattttata
     7081 tctagttata tgaaaatacg tcataaaaag aaaagtataa actaagccct atagggtggc
     7141 ttcgcaccac ctttagaaag aagaataacg tgaaatttaa tgaattaaac ttgtctgctg
     7201 atttgctagc agaaattgaa aaagctggtt ttgtagaagc tagtcctatc caagaacaaa
     7261 ctattccttt ggcccttgaa ggcaaggatg ttatcggtca agctcagact ggtacaggaa
     7321 aaactgcagc ctttggcttg cctacccttg aaaaaatccg tacagaagaa gcgactatcc
     7381 aagccttggt catcgctcca actcgtgaac tagctgtcca aagtcaagaa gaactcttcc
     7441 gctttggtcg tagtaaggga gtcaaagtcc gttcagtata tggcggatca agcattgaaa
     7501 aacaaattaa ggctcttaaa tctggtgccc atattgtggt gggaactcca ggtcgcctct
     7561 tggacttgat taaacgcaag gccttgaaat tacaagacat tgaaaccctt atccttgacg
     7621 aagcggatga aatgcttaac atgggcttcc ttgaagacat cgaagccatt atttcccgtg
     7681 tacctgagaa ccgtcaaact ttgcttttct cagcaactat gccagatgcc atcaaacgta
     7741 tcggtgttca gtttatgaaa gcccctgaac atgtcaagat tgcggctaag gaattgacaa
     7801 cagaattggt tgaccagtac tatatccgtg ttaaggaaca agaaaaattt gacaccatga
     7861 ctcgtctcat ggatgtggca caaccagaac tcgctattgt atttggtcgt accaaacgcc
     7921 gtgtggatga attgactcgt ggtttgaaaa ttcgtggctt ccgtgcagaa ggaattcatg
     7981 gcgacctaga ccaaaacaaa cgtcttcgtg tccttcgtga ctttaaaaat ggcaatcttg
     8041 atgttttggt tgcgacagac gttgcagcgc gtggtttgga tatttcaggt gtgacccatg
     8101 tctacaacta cgatattcca caagatcctg agagttatgt tcaccgtatc ggtcgtacag
     8161 gtcgtgctgg taagtcaggt caatctatta cttttgttgc tccaaacgaa atgggttacc
     8221 ttcaaatcat tgaaaacttg actaagaaac gcatgaaagg tctcaaacct gcaagtgtag
     8281 aagaatcctt ccaatcaaaa aaacaggtag ctctcaagaa aatcgaacgt gattttgcag
     8341 atgaaaccat tcgtgccaac tttgagaaat ttggtaagga tgctcgcaaa ttggctgctg
     8401 agtttactcc agaagaattg gcaatgtata tcttgagtct gacagtccaa gacccagata
     8461 gccttccaga agtggagatt gcacgtgaaa aaccactacc gtttaaacca tcaggtaatg
     8521 gtttcggtgg taaagctaag ggaggtcgtg gaggccgtcg tggggacgac cgtcgagagc
     8581 gtgatcgccg tggcaatggt cgccgtgatg agttcaaaaa aggaagtcgt ggcaacgatc
     8641 gttttgataa ggaaaaacgt taccgtaagg ataataaaaa accacgcaat actttaagcg
     8701 aaaagcaaac aggctttgtt attcgtaaca aaggcgataa ataagaaaaa gcggttcaaa
     8761 atgaatcgct tttttatata aggagaccga atgtgaaaag acaaataaaa ttattatatt
     8821 atcttttata atgttataat acacaaaaat aggcaacttg tcaatagaaa aggaacaatt
     8881 taattaaaaa tattctggtt tttaattaaa ttgtaagtca atgcaagtca ataaggaatt
     8941 ttcagataat tattgaaaaa gagacgtttt tatgttataa tgatagcgat taaattcgag
     9001 gtgaaaaatg gcacatttat tagaaaaaac tagaaaaatt acatcaattt tgaaacgctc
     9061 agaggagcag ttgcaggatg agcttcctta caacgctatt acgcgtcagt tagcggatat
     9121 tattcattgc aatgcctgca ttatcaatag taagggacgt ctgcttggct attttatgcg
     9181 ttataaaaca aatacagatc gcgtagagca attcttccaa actaagattt tcccagatga
     9241 ctacgttcaa ggggctaata tgatttacga aacagaagca aacttacctg ttgagcatga
     9301 tatgagtatt ttccctgttg agagtagaga tgattttcca gatggcttga cgactattgc
     9361 accgattcat gtatcgggga ttcgccttgg ttctttgatt atttggcgta atgataaaaa
     9421 attcgaagat gaggacttgg ttcttgttga gattgccagt accgttgttg ggattcagct
     9481 tcttaacttc caacgtgaag aagatgagaa aaatattcgt cgtcgtactg ctgtcaccat
     9541 ggcggtcaat accctttctt actccgaact ccgtgctgtt tcagcaattt taggggaatt
     9601 aaatggaaat gaagggaagt tgactgcgtc agtgattgca gatcgtatcg gaatcactcg
     9661 ctctgtgatt gtcaatgctc ttcgtaaact tgagtctgcg gggattattg aaagtcgctc
     9721 acttggaatg aagggaacct atcttaaggt cttgatttca gatatttttg aagaagtgaa
     9781 gaaaagagat tactaatgac aaaggcttta atttcgattg attatacaga agattttgtt
     9841 gctgatagtg ggaaactaac agcaggtgct ccagctcagg cgatttcgga tgccatcagc
     9901 aaggtaactc gattagcttt tgaacgagga gattatatct tctttactat tgatgctcat
     9961 gaagaaaacg attgtttcca tccggaaagt aagttatttc ctcctcataa tctgattggg
    10021 acgagtggac ggaatttata tggagatttg gggatctttt atcaagagca tggttcagac
    10081 agtcgtgtct tttggatgga taaacgccat tactcagctt tttcagggac tgacctagat
    10141 attcgtttga gagagcgtag agtgtctacc gttatcttaa caggtgtctt gacggatatc
    10201 tgtgtcctac atacagctat agatgcctat aatctaggat atgacatcga gattgttaaa
    10261 ccagctgttg cttccatctg gcctgaaaat catcaatttg ccctaggtca tttcaaaaat
    10321 acactcggag ctaagttagt agatgaaaat ctaaatgaac tttctgagta acctggttgg
    10381 tgaaaatgaa aaaatttgaa aaaaagtgtt gacaagcatc ccaaaagttg atatactagt
    10441 aaagtaatcg acgcggggat ggcggaattg gcagacgcgc aggactaagg atcctgtgac
    10501 cgctttaggt cgtgagggtt caagtccctc tctccgcata ggaaaagagc tagctaaagc
    10561 tagctctttt gtatttctct aaaaaattag aatccagtca aatgtagtgg agaatcagcg
    10621 aaaatatggg aaaactgatc cttgtttctg cttttgtcat agaagaataa taaagattat
    10681 cttcttcaaa ttctccgata ttctctaaag ttttgtgcaa gttgcacaga acttgtttat
    10741 ttttttggtc atcttgccat agaaatataa agcgttttca tatataatat aattatcaaa
    10801 agacaaaagg agttcacctc atggtagaat tgaatcttaa aaatatttac aaaaaatatc
    10861 caaacagcga acactattca gttgaagatt tcaacttgaa catcaaagat aaagaattta
    10921 tcgttttcgt aggaccttca ggatgtggta aatcaactac actccgtatg attgctggtc
    10981 ttgaagacat tacagaaggt actgcatcta tcgatggcgt agttgtcaac gacgtagctc
    11041 caaaagaccg tgatatcgcc atggtattcc aaaactacgc tctttaccca cacatgactg
    11101 tttatgacaa catggctttc ggtttgaaat tgcgtaaata cagcaaagaa gacattaaca
    11161 aacgtgttca agaagcagct gaaatacttg gattgaaaga attcttggaa cgtaaaccag
    11221 ctgacctttc aggtggtcaa cgtcaacgtg ttgccatggg gcgtgcgatt gtccgtgatg
    11281 cgaaagtatt cttgatggac gaacctttgt caaacttgga tgccaaactt cgtgtatcaa
    11341 tgcgtgctga aatcgctaaa attcaccgtc gtatcggagc tacaactatc tatgtaactc
    11401 acgaccaaac agaagcgatg acacttgcag accgtatcgt tattatgtca gctactaaga
    11461 accctgctgg tacaggtact atcggacgtg tagaacaaat cggtactcct caagaagttt
    11521 acaaaaatcc agttaacaaa ttcgttgcag gattcatcgg aagcccagct atgaacttca
    11581 tcaacgtgaa attggttggt agcgaaattg tttctgacgg tttccgtttg aaagtgccag
    11641 aaggagcatt gaaagttctt cgtgaaaaag gctacgaagg aaaagaattg atctttggta
    11701 tccgtccaga agacgtgaat gcagaacctg ctttccttga aacattccca gactgtgttg
    11761 taaaagcgac tatctctgta tcagaactgc ttggttcaga atctcacctt tactgccaag
    11821 ttggtaaaga cgagtttgtt gcaaaagttg atgctcgtga ctacttgcaa acaggtgcaa
    11881 cagttgagct tggatttgac ttgaacaaag cacacttctt cgatgtagaa actgaaaaaa
    11941 caatctacta aaataaataa aattcaaagc actacaagaa aagatatctc tttatcaatt
    12001 gtagtggaga gatatcagtt aatctaggga gagaaacaaa atgcttctct cctttttgct
    12061 agggaagtca tattatgcat ctatattgtg atgctcttta atactcttcg aaaatctctt
    12121 caaaccacgt caacgtcgcc ttgccgtacg tatgattact gatttcgtca gttttatctg
    12181 caacctcaaa gatgtacttt gagcagctta cggctagttt cctagtttgc tctttgattt
    12241 ccattgagta ttatttgtgg gtaccatcta caagtgaagc tatatgcgta aactacgtga
    12301 gcaattgaat tcgaactaga gaggtaataa taaatttatg ctatagttat ggtgacttgt
    12361 atgcttttga ttctagttta tcaaataata gattagaatt gtcagataat atcattttgt
    12421 gttataatga agaaaaaaca gaggtgttca aatgtcagaa gcaggtcata agtttttagc
    12481 aaaattgggg aaaaaacgct tacgtccagg tggaaagcgt gccacagatt ggttaattgc
    12541 agaaggagga ttttcaaaag aaaagagaat actagaggtt gcgtgtaata ggggaactac
    12601 agcaattgag ttggcacagc gttttggttg caagataact gctgttgata tggatgctca
    12661 agctttagaa gtggctaaaa aatctgctgg aacggcaggt gttgctcatt taatcagttt
    12721 tgaaagagca aatgcaatga aacttcctta tcaagatgct agttttgata ttgttataaa
    12781 tgaagctatg ctgactatgc aagccgatca agctaagaaa aaatgtgtaa tggaatatct
    12841 aagggtatta aaacctggag gtcttctctt gacacatgat gtgcttctta aggaagctaa
    12901 agagtctatc agacaggaat tatcacaagc aattcatgta aatgtaggtc ctttaactca
    12961 agatggttgg gaacaggtga tgatagaatc aggttattgt gatgtgaaag cattgactgg
    13021 tgaaatgaca ttaatgaaat tatcgggtat gatttatgac gaaggtttgc taggaacttt
    13081 gaaaatttgt gtaaatgctt gtaaaaagga gaatagaaag cagtttttaa ctatgtataa
    13141 aatgtttgct aagaataaac agaaattggg ctttattgcg atggctagtt ataaatcgtc
    13201 aaaacgttag ataattattg aagttaactt ttcctttttt ctttcttaaa aaatatgcta
    13261 taatagagag taaaaaactt tgaaagaaag aaaaaagatg aatttaaaag attacattgc
    13321 aacaattgaa aattatccaa aggaaggcat taccttccgt gatattagtc ctttgatggc
    13381 tgatggaaat gcttatagct acgctgttcg tgaaatcgtt cagtatgcta ctgacaagaa
    13441 agtcgacatg atcgtgggac ctgaagctcg tggatttatc gtgggttgtc cagttgcctt
    13501 tgagttggga attggttttg cgcctgttcg taagccaggt aaattgccac gtgaagttat
    13561 ttctgctgac tatgaaaaag agtacggtgt cgataccttg actatgcacg cggatgccat
    13621 taagccaggt caacgtgttc ttattgtaga tgaccttttg gcgacaggtg gaactgttaa
    13681 ggcaactatc gagatgattg aaaaacttgg tggtgttatg gcaggttgtg ccttccttgt
    13741 tgaattggat gaattgaacg gccgtgaaaa aattggtgac tacgactaca aagttcttat
    13801 gcattattaa tgaaaacagt ccctagggct gttttctcta cactaggata taaaaataga
    13861 ctataactag ttagagaaaa actataattg aaaactatat cttcttgcag tataataaaa
    13921 ggactaagtg tttgagattt gtcttcaaac atatgcaatt attcctgaaa gagtacagtt
    13981 aggagagggt tatgccgatt cgaattgata aaaaattgcc agctgttgag attttacgga
    14041 cagagaatat ctttgtcatg gatgatcaac gtgctgccca ccaagatatc cgtcctttga
    14101 agattttaat tttaaatctc atgccacaga aaatggtcac agagacccag ttgttgcgcc
    14161 acttggctaa tacaccccta caactggata ttgattttct ctatatggag agccaccgtt
    14221 ctaaaacaac tcgttcagag cacatggaga ccttctataa aacttttcct gaagtcaagg
    14281 atgagtattt tgatgggatg atcatcacgg gtgctccagt tgagcattta ccatttgagg
    14341 aagtggacta ttgggaggaa tttagacaga tgcttgagtg gtctaagact catgtctatt
    14401 cgacccttca tatctgttgg ggggctcagg ctgggcttta tctgcgctat ggtgtagaaa
    14461 aataccagat ggacagtaag ctatcaggta tttatcctca ggacacccta aaagagggtc
    14521 accttctatt tagaggcttt gatgatagct atgtatcccc tcattcacgg cacacggaga
    14581 tttctaagga agaggtctta aacaagacca atctcgagat tttatcagaa ggacctcagg
    14641 ttggggtttc tattttggcc agtcgtgatt tacgagaaat ttatagtttt ggtcatttgg
    14701 agtatgaccg tgataccttg gcaaaagagt attttcgaga tcgtgatgca ggtttcgacc
    14761 cacatattcc agaaaattac tttaaagatg atgatgttaa tcaggtacct tgtctttgtt
    14821 ggtcttcatc tgcagccctc tttttcagta attgggtaaa ccatgcggtc tatcaggaga
    14881 cgccttttga ttggagaaag atagaagatg atgcatctgc atatgggtat ttataagagg
    14941 aattatgaca tatttagacg cttttaaatc aggtaccttg gttttaccga gtgccctgct
    15001 cttgcatttt aaggaactct ttccttctag cgacgatttt ctggtttggc aatttttcta
    15061 tttgcaaaat acgacaggct tagaagaaat gtcgccaagc cagattgctg aaaggattgg
    15121 caaggaaatt tcggatgtca accagtccat ttctaatctg acggaaaggg gactgctcca
    15181 gtatcgtact atcgaattaa atggcgaaat tgaattgctc tttgatgcta gtttggcctt
    15241 ggaacgtttg gatgacctgt ttggagcagt tcattcaagt tcagaccagc taacatctca
    15301 aaaccagctc aaggatttgg tggaaacctt ccagcaggag ttgggacgat tgttgacgcc
    15361 ttttgagatt gaggatttga ccaagacact aaaggaagat ggaaccagtg ctgacttgat
    15421 taaggaggct cttcgtgaag ctgttttgaa tggaaaacca aactggaagt acattcaggc
    15481 gattttgaga aactggcgcc atgaaggaat caagagtgtg gctcaaattg aggccaagag
    15541 agcagaaaga gaagcaagca atcctcagtt gacacaggta tctgcagatt tcagaaatgc
    15601 catggatctc tggaaggatt aatccatgca agtaggcttg aaatccgagt aagatttgca
    15661 agctgtgtat aattgtgata gaataaatag aaaataaatt gaaaaaagag gtatgtgaaa
    15721 tgtcacgtaa accatttatc gctggtaact ggaaaatgaa caaaaatcca gaagaagcta
    15781 aagcattcgt tgaagcagtt gcatcaaaac ttccttcatc agatcttgtt gaagcaggta
    15841 tcgctgctcc agctcttgat ttgacaactg ttcttgctgt tgcaaaaggc tcaaacctta
    15901 aagttgctgc tcaaaactgc tactttgaaa atgcaggtgc tttcactggt gaaactagcc
    15961 cacaagtttt gaaagaaatc ggtactgact acgttgttat cggtcactca gaacgccgtg
    16021 actacttcca tgaaactgac gaagatatca acaaaaaagc aaaagcaatc tttgcgaacg
    16081 gtatgcttcc aatcatctgt tgtggtgaat cacttgaaac ttacgaagct ggtaaagctg
    16141 ctgaattcgt aggtgctcaa gtatctgctg cattggctgg attgactgct gaacaagttg
    16201 ctgcctcagt tatcgcttat gagccaatct gggctatcgg tactggtaaa tcagcttcac
    16261 aagacgatgc acaaaaaatg tgtaaagttg ttcgtgacgt tgtagctgct gactttggtc
    16321 aagaagtcgc agacaaagtt cgtgttcaat acggtggttc tgttaaacct gaaaatgttg
    16381 cttcatacat ggcttgccca gacgttgacg gtgcccttgt aggtggtgcg tcacttgaag
    16441 ctgaaagctt cttggctttg cttgactttg taaaataatc agtaagtagc aaaagctagg
    16501 tggaacagca ttcagatgtc tgttacattt tttataggag agcaaagatt gaaaacaaaa
    16561 attggattag caagtatctg tttactaggc ttggcaacta gtcatgtcgc tgcaaatgaa
    16621 actgaagtag caaaaacttc gcaggataca acgacagctt caagtagttc agagcaaaat
    16681 cagtcttcta ataaaacgca aacgagcgca gaagtacaga ctaatgctgc tgcccactgg
    16741 gatggggatt attatgtaaa ggatgatggt tctaaagctc aaagtgaatg gatttttgac
    16801 aactactata aggcttggtt ttatattaat tcagatggtc gttactcgca gaatgaatgg
    16861 catggaaatt actacctgaa atcaggtgga tatatggccc aaaacgagtg gatctatgac
    16921 agtaattaca agagttggtt ttatctcaag tcagatgggg cttatgctca tcaagaatgg
    16981 caattgattg gaaataagtg gtactacttc aagaagtggg gttacatggc taaaagccaa
    17041 tggcaaggaa gttatttctt gaatggtcaa ggagctatga tgcaaaatga atggctctat
    17101 gatccagcct attctgctta tttttatcta aaatccgatg gaacttatgc taaccaagag
    17161 tggcaaaaag tgggcggcaa atggtactat ttcaagaagt ggggctatat ggctcggaat
    17221 gagtggcaag gcaactacta tttgactgga agtggtgcta tggcgactga cgaagtgatt
    17281 atggatggtg ctcgctatat ctttgcggcc tctggtgagc tcaaagaaaa gaaagatttg
    17341 aatgtcggct gggttcacag agatggtaaa cgctatttct ttaataatag agaagaacaa
    17401 gtgggaaccg aacatgctaa gaaaatcatt gatattagtg agcacaatgg tcgtatcaat
    17461 gattggaaaa aggttattga tgagaacgag gtggatggtg tcattgttcg tctaggttat
    17521 agcggtaaag aagacaagga attggcgcat aacattaagg agttaaaacg tctgggaatt
    17581 ccttatggtg tctatctcta tacctatgct gaaaatgaga ccgatgctga gaatgacgct
    17641 aaacagacca ttgaacttat aaagaaatac aatatgaacc tgtcttaccc tatctattat
    17701 gatgttgaga actgggaata tgtaaataag agcaagagag ctccaagtga tacagacact
    17761 tgggttaaaa tcatcaacaa gtacatggac acgatgaagc aggcgggtta tcaaaatgtg
    17821 tatgtctata gctatcgtag tttattacag acgcgtttaa aacacccaga tattttaaaa
    17881 catgtaaact gggtagcggc ctatacgaat gctttagaat gggaaaaccc ttattattca
    17941 ggagaaaaag gttggcaata tacctcttct gaatacatga aaggaatcca agggcgcgta
    18001 gatgtcagcg tttggtatta agcgatgatt tgaaagaggg atgtgatagt agcaccctct
    18061 ttttctttgt tttatgatag ttcatcctcg agtaaattca agatcttgct cggaaatgaa
    18121 gcttatatag tagattgaat atagacaaat accttgtgat tggtaaaaca ttttagaaat
    18181 tcatttacct ttcctaatcg acttggtttc atcttatttc aatctattat agtattgggg
    18241 aatttcttca aaccacatca gcttggtcag ttctacctgc gacctcaaaa cttgtgcttt
    18301 ggtcaagctg ggtttagttt cctagtttgc tgatggattt ccattgacta taagcatcca
    18361 accctctttt tgtcttctaa agaattctta aattatcagt ctattgcaac ttttctcatg
    18421 tgggtcattt ggcttgcaat tgtctttcct tagtagtata ctgaggtagt aatcattaag
    18481 aagtggttac ataaaaataa tgaatgaggt aaaataaaat ggtagaattg aaaaaagaag
    18541 cagcaaaaga tgtcgcaaca ttaacaaaag cagcgccagt agcattggca aaaacaaagg
    18601 aagttttgaa tcaagcagtt gctgatttgt atgtagctca cgttgctttg caccaagtgc
    18661 actggtatat gcatggtcgt ggtttccttg tatggcatcc aaaaatggat gagtacatgg
    18721 aagctcttga tggtcattta gatgaaatca gcgaacgctt gatcacactt ggtggaagcc
    18781 cattctctac tttgacagag ttccttcaaa acagtgaaat cgaagaagaa gctggtgaat
    18841 accgtaatgt tgaagaaagc ttggaacgtg ttctagctat ttatcgctac ctcatcactc
    18901 ttttccaaaa agcgttggat gtgactgacg aagaaggcga tgatgttaca aacgatattt
    18961 ttgttggtgc taaggctgaa cttgagaaaa cagtttggat gcttgccgca gaacttggac
    19021 aagcacctgg tttgtaagaa acaagacaac atagataaat ctgtaggaaa tttcttacag
    19081 attttttcta ttttgtaagc tattccaaac cagtcttttt ttgagttttt tgataaaata
    19141 gtactatcag tgaaaaggat ggaagcatga ctaagaaaat cgtagctatt tgggcccagg
    19201 atgaagaggg tgtgattggt aaggacaatc gtctgccttg gcatttgcca gcagaattgc
    19261 agcactttaa agaaacaact ctgaatcatg ctatcttgat ggggcgggta acctttgatg
    19321 gaatggggcg tcgcttgctt ccaaaacggg agaccctgat tttgacgcgt aatccggaag
    19381 aaaagataga tggggttgct acttttcagg acgtccagtc tgttcttgac tggtatcagg
    19441 ctcaagaaaa gaatctctac attatcggtg ggaagcaaat ttttcaggct tttgaagctt
    19501 accttgatga agtgattgtc actcacattc atgctcgggt ggaaggagat acctatttcc
    19561 ctgaagagct tgacttgtct ctttttgaga cagtttcaag caaattttac gccaaagatg
    19621 agaagaatcc ttatgatttt accatccaat accgcaagag aaaggaagta taatggaacg
    19681 gagtttattt ggtctattca cggcttttct gtgtttcatc tgctttctgg caggagcaca
    19741 ggcttttcgt aaaaagcgtt acgggctttc tatcctcctt tggttaaatg cctttaccaa
    19801 tctggtcaat agtattcatg ctttttacat gaccttattt tagatagaat gacagtatag
    19861 aatggaagga aatcatgtct acaaatagaa aaaatgatat gatggtttat tgctcatttt
    19921 gtggcaaaaa ccaagaagaa gtacaaaaaa taattgctgg caacaatgct tttatttgta
    19981 atgaatgcgt ggagttagct caggaaatca ttcgagaaga attggttgag gaagtcttgg
    20041 cagacttgtc tgaggtgcca aaaccaattg aactcctcca tatcttgaac cactatgtaa
    20101 ttggtcaaga tcgtgccaag cgtgccttgg cagtggcggt ttataaccac tacaaacgca
    20161 tcaatttcca cgatacacgc gaagagtcag aagatgtgga tttgcagaag tcaaacattt
    20221 tgatgattgg cccaactggt tcagggaaaa ctttccttgc ccagaccttg gctaagagct
    20281 tgaatgtgcc ttttgctatt gcggatgcga cagctctgac ggaggctggt tatgtgggtg
    20341 aggacgtgga aaatatcctc ctcaaactct tgcaggttgc tgactttaac atcgaacgtg
    20401 cagagcgtgg cattatctat gtggatgaaa ttgacaagat tgccaagaag agtgagaatg
    20461 tgtctatcac acgtgatgtt tctggtgaag gggtgcaaca agcccttctc aagattatcg
    20521 agggaactgt tgctagcgtg ccgcctcaag gtggacgcaa acatccacaa caagagatga
    20581 ttcaagtgga tacaaaaaat atcctcttca tcgtgggtgg tgcttttgat ggtattgaag
    20641 aaattgtcaa acaacgtatg ggtgaaaaag tcatcggatt tggtcaaaac aataaggcga
    20701 ttgacgaaaa cagctcatac atgcaagaaa tcatcgctga agacattcaa aaatttggta
    20761 ttatccctga gttgattgga cgcttgcctg tttttgcggc tcttgagcaa ttgaccgttg
    20821 atgacttggt tcgcatcttg aaagagccaa gaaatgcctt ggtgaaacaa taccaaacct
    20881 tgctttctta tgatgatgtt gagttggaat ttgacgacga agcccttcaa gagattgcta
    20941 ataaagcaat cgaacggaag acaggggcgc gtggacttcg ctccatcatc gaagaaacca
    21001 tgctagatgt catgtttgag gtgccgagtc aggaaaatgt gaaattggtt cgcatcacta
    21061 aagaaactgt cgatggaacg gataaaccga ttctagaaac agcctagagg tgactatgga
    21121 acttaataca cacaatgctg aaatcttgct cagtgcagct aataagtccc actatccgca
    21181 ggatgaactg ccagagattg ccctagcagg gcgttcaaat gttggtaaat ccagctttat
    21241 caacactatg ttgaaccgta agaatctcgc ccgtacatca ggaaaacctg gtaaaaccca
    21301 gctcctgaac ttttttaaca ttgatgacaa gatgcgcttt gtggatgtgc ctggttatgg
    21361 ctatgctcgt gtttctaaaa aggaacgtga aaagtggggg tgcatgattg aggagtactt
    21421 aacgactcgg gaaaatctcc gtgcggttgt cagtctagtt gaccttcgtc atgacccgtc
    21481 agcagatgat gtgcagatgt acgaatttct caagtattat gagattccag tcatcattgt
    21541 ggcgaccaag gcggacaaga ttcctcgtgg taaatggaac aagcatgaat cagcaatcaa
    21601 aaagaaatta aactttgacc caagtgacga tttcatcctc ttttcatctg tcagcaaggc
    21661 agggatggat gaggcttggg atgcaatctt agaaaaattg tgaggaaaag aaaatggcaa
    21721 aaacaattca tacagataag gccccaaagg ctatcggacc ctatgttcaa ggaaaaatcg
    21781 ttggcaacct tttgtttgct agcggtcaag ttcccctatc ccctgaaact ggggaaattg
    21841 taggagagaa tatccaagaa cagacagagc aagtcttgaa aaacatcggt gctattttgg
    21901 cagaagcagg aacagacttt gaccatgttg tcaaaacaac ttgcttcttg agcgatatga
    21961 acgactttgt tccttttaat gaggtttacc aaacggcctt caaagaggaa ttcccagctc
    22021 gttcagctgt ggaggtagct cgtcttcctc gtgatgtaaa agtcgaaatt gaagtcatcg
    22081 cagagattgg ataagctagt tgaagtttgg tgttgccaaa cttcttttga tataaggaga
    22141 aaaagatgac aaagaaacaa cttcacttgg tgattgtgac agggatgagt ggcgcaggga
    22201 aaactgtagc cattcagtcc ttcgaggatc taggttattt caccattgat aatatgccgc
    22261 cagctctctt gcctaagttt ttgcagctgg ttgaaattaa ggaagacaat cctaagttgg
    22321 ccttggtagt ggatatgcgt agccgttctt tcttttcaga gattcaagct gttttggatg
    22381 agttggaaaa tcaagatggt ttggatttca aaatcctctt tttggatgcg gctgataagg
    22441 aattggtcgc tcgttacaag gaaaccagac ggagtcaccc actagcagca gacggtcgta
    22501 ttttagatgg aatcaagttg gaacgtgaac tcttggcacc tttgaaaaat atgagccaaa
    22561 atgtggtgga tacgactgaa ctcactccac gtgagctgcg caaaaccctt gcagagcagt
    22621 tttcagacca agaacaagcc cagtctttcc gtatcgaagt catgtctttc ggatttaagt
    22681 atggaatccc gattgatgcg gacttggtct ttgatgtccg tttcttgcca aatccctatt
    22741 atttaccaga actgagaaac caaacgggtg tggatgaacc tgtttatgat tatgtcatga
    22801 accatcctga gtcagaagac ttttatcaac atttattggc cttgattgag ccgattctgc
    22861 caagttacca aaaggaaggt aagtccgttt tgaccattgc catgggatgt acgggtggac
    22921 aacaccgtag tgtggcattt gctaaacgct tggtgcagga cttatccaag aattggtctg
    22981 ttaatgaagg gcatcgcgac aaagaccgca gaaaggaaac ggtaaaccgt tcatgagaaa
    23041 accaaagata acggtgattg gtggagggac tggaattccc gtcattctaa aaagtctgcg
    23101 ggaaaaagat gtggaaatcg cagctatcgt gacggtggca gatgatggtg gttcttcagg
    23161 tgaactccga aaaaatatgc aacagttgac accgccaggt gatcttcgta atgtccttgt
    23221 ggccatgtcg gatatgccta agttttatga gaaggtcttt cagtatcggt tctctgagga
    23281 tgccggagcc tttgctggcc atccattggg aaatctcatc attgctggct tgtcagaaat
    23341 gcagggttca acctataatg ccatgcagtt attgagcaaa tttttccata caacagggaa
    23401 aatttatcct tccagtgacc atcctttgac ccttcatgca gtctttcagg atgggacaga
    23461 agtggctgga gagagtcata ttgtagacca tcgaggcata attgacaatg tctatgtgac
    23521 caatgcccta aacgatgata cgcctctggc cagccgtcga gtagtgcaga ccatccttga
    23581 aagtgacatg attgtcctag ggccaggttc tctctttacc tctattttgc ccaatatcgt
    23641 gattaaggaa attgggcggg ctcttttgga aaccaaggca gaaattgcct atgtctgcaa
    23701 tatcatgacc caacgtgggg agacggaaca ctttacagat agcgaccacg tggaagtctt
    23761 gcatcgtcac cttggtcgcc cttttatcga cactgtcttg gtgaatattg aaaaagtgcc
    23821 tcaggaatac atgaattcca accgttttga tgaatacttg gtgcaagtgg aacacgattt
    23881 tgtaggtctt tgtaagcaag tttcgcgcgt gatttcatct aacttccttc gtctggaaaa
    23941 tggcggtgcc ttccacgatg gagatttgat tgtggacgag ttgatgcgca ttatacaggt
    24001 gaaaaaatga gtttcacagt agcagtaaaa gaagaaatcc tgggccaaca ccatctgagc
    24061 tggcatgaat tatctgccat tatcaaaatg tctggtagca tcggtctctc gacttcgggc
    24121 ttgactttgt cagttgtgac agaaaatgcc aaactggccc gtcacctcta tgagtccttt
    24181 ctccatttct atgaaatcaa atctgaaatt cgtcaccacc aacggagcaa tcttcgcaag
    24241 aatcgcgtct ataccgtttt tacagatgaa aaggtgcagg atttgttaag tgatttgcac
    24301 ttggcagact ctttctttgg cctggaaaca ggtattgatg aggcgatttt atcggatgag
    24361 gaagcaggtc gtgcctatct ctgtggcgct ttcttggcaa atgggagcat tcgtgaccct
    24421 gagtcaggca agtaccagtt ggaaatcagt tctgtttatc tggaccacgc gcaaggaatt
    24481 gcctcccttc tccaacagtt tttactggat gccaaggtgc ttgagcgcaa gaagggggct
    24541 gtgacctatc tccagcgagc agaagacatt atggacttct tgatagtaat cggagccatg
    24601 caggcacgtg atgattttga gcgggttaag attttgcgag aaacccgtaa cgacctcaat
    24661 cgggctaata atgccgagac agctaatatc gctcggacag tttctgccag catgaagacc
    24721 attaacaata tcagtaaaat aaaagatatc atgggcttag aaaatttgcc agtagatttg
    24781 caggaagtgg cgcaactgag gattcagcac ccagactact ctatccaaca gttggcagat
    24841 agcctcagca cccctctgac caaaagtggt gtcaatcaca gactcagaaa aatcaataag
    24901 atagcggatg aattataacg atataaagca accccttgaa ttatcaatat cttcaagggg
    24961 ttttgttgtg ttatgaaatc aaaaaggggc aaccaagggg cagaattaaa aaatagtatc
    25021 taatttattg accagtttat cctccatatc ttcagtagta tgagaataga tttccaaagt
    25081 catttttgca tttgagtgcc caactcgatc catcattgat tttattggga ggccagactc
    25141 tgctaaaaac gaaatatgag aatgcctaaa aatatggcta gataaatttt tttctatttt
    25201 ggcctgtttt ccatattttt ttaatatctg tatgaagcaa gctattgttg taggttgatt
    25261 ccatttttca aaacagaaaa tataatcatc gcttgacaat ggctggaaac gttcgctaag
    25321 tcgtactatt tgtctttgaa tagcttctat gacactctct gatactttga ttgtccgtat
    25381 tgaatttgta gtctttggta gcgtcttgat tttgtttact gaatcaaaat tacctgtgat
    25441 ctcaattttg ttgttttcga agtctatatt cttcagttgt aaggcagtta actcaccata
    25501 tctcatacca gttaatgtca gcacaagaac catatcagcg tacttttggt gatattctcg
    25561 acgattaagg acatcgacaa gtgcttttat ttcttgcatg gtgagaaagt tgttacgctt
    25621 tttttccagt tcttctaaag tctttggttt ttgaggaatc gtagtataat cgacctcgtt
    25681 gttttcaatg taagagtatt gaacagcgta attaaagata cctctgagcc tatgccgtac
    25741 ttttttagct gtaatatatc cgttgctttc aataattttt tcaatagcct cttgaagaaa
    25801 acgcctgtca agattagcaa gtatggtatc ggatggtatg acttctttca tcttcttatc
    25861 aactgattta caattatgtt ttgttgattc ctttactgtt tgcgcccatg atttatagaa
    25921 aaggttatag atttcttcaa atgtaatgct ttctacttgt tttgtgctga gttttttatt
    25981 tatcttctct tgtaacaaga tagcagcttg atttcttgcc tggggagttt tcttctccat
    26041 ggttactgaa acttttttta atttctcagt atatggatct ttatatcgct caaaaaattt
    26101 atatttgccg tttggcaatt cttccatcca cattgcgttt acctcacttt tttgttaaaa
    26161 tgggtatagt aaaaagggct ttttaatgcc ttttactata ctggatatcc tcacactcaa
    26221 agtttggcga tggcgagtgt gaggattttt tgtttttata gttattctga tgaactatcc
    26281 tatcaattca taatattcgt caattaccat caattcgtct gtgactgttc taagcttatg
    26341 tttttgcatg aactggatat agttgaaaga ttgatggtcg tctgatagtg caagttcttc
    26401 ttctagcaac ttatgaatca tgtgcctatt agcctcattc tcgcacctag tgtggttgtt
    26461 ttgatatagt gcagtagaat gttccagatg tcctaattcg tggtatatga cccgtttttt
    26521 tgcatcttcg gacagttcac ggtttataaa gataatactg atttctttga tataaactcc
    26581 aggtctttgc caaagttcgt tatcaaagta agcgagagtg acaccgtgtg agtcaactag
    26641 ctcttcaata gtcataggct atcatccttc aaatattttt taaaattagt tgttttatct
    26701 cttgaactag agtaaaatag aattgaaagg aagtgattaa aatgaagttg aaactctatg
    26761 cacatttagc tgtactgttt caagtttcag catttgtttt tttgatttgt tacttttttc
    26821 taagacaaat cctaacactt ccaatcatcg ttttactcag tttcgttatt tctgaaatta
    26881 ttcttcgact ttttctggag attcgagtag ttcatcttga agaatcctag ttgctacttc
    26941 tggagcttta atatctagtt gagatgtagc gcctttaaac tgcggactca tccctttatc
    27001 tattaacaat gcaatagcct cggcatttat tttatttgcc tgggcttttt tgattgcttc
    27061 atccccatcg ctatttaact gagctttaaa tttcccaagc ttagaatcaa cttcaaagtt
    27121 tgcaccattg cgtttaatta aattgcgaaa agcaattcct ccagttagaa taatgataaa
    27181 tactagaacc gggattagta tttcaggatg tccaagtagt tcaatcggcc ctttcgattg
    27241 gacgttggtt cttagaacga ctttctcatc ttttaattca tcagattctt ttacaacatt
    27301 gaccatttgc aagacagtgt gcagaaatgt tgagtattca aaagcatcaa tattgttttc
    27361 ctcttgtact ttgaaagtga tactcatgtg gtcatgatcg atgtaggcat catatagacc
    27421 tcggttgatg aattttttgt aggcatttgc atcagtgatg gtatggcctg aatagactaa
    27481 tttgtaaagt ttcgggtcaa tatctctgtt tggtatgact ccaaaccagt gcacattcat
    27541 tcgcttatta aatgggcaaa cgttagatgc ggactctatg ttgctttcac tctctgtata
    27601 gggtctgctc gttatttcac ctacaagaaa atcgttagga gattctgacg gaacaatgac
    27661 aatgtctccg attttaagac tatacgcaaa cttcatcatt tgattgtagg cagaaccagg
    27721 cttttctatc ctactgtcaa actccttgat ttttcctttg attgcatctt cgtcaagatt
    27781 tttaaggtca tctaatgtta tatagttcca tccaatggcg atatagccac cagtttgaaa
    27841 acttttatag aattgccctt tttgagccct tacaaaccaa taatctttag aactatcaac
    27901 agacgggagt tgatgatata tgttttcaaa aagggtattg aaaagcaagg catcttgttc
    27961 ggtaatcgtc atactatcta cctctcaagt atatttctat gatgttttga atcgcatcga
    28021 tatcctcttc tgtaagtggc ttaccatcga aggttttggc attctctgcc atctttcgga
    28081 ggtcgtcaga cgtgtatcct gagattgtat catcaccagc aatagcagga ttatcagtac
    28141 gaccaagtaa gtagtctgta gatacgttga agtagtcagc gatctgttgc aatctttcag
    28201 agtttggggt tttcgttttt aaagtataga aataattggt actatatcct agactttctt
    28261 ctagttttgt tagaggaatc cctctttttt tagctaattc tttaattttt tctagcgttg
    28321 aaaacattgt taaatcaacc tttctaaggg tatcacaaaa aatatttcta aaattctaga
    28381 aaaaagtatt gacacaatct agaaaaaagt atagaatagt ttttgtaagt aagttacaac
    28441 taaaaaaaca actaagaaat aaattataaa aatgttttgg cgaacggtat ttatagtttt
    28501 attagtgttt ttgttatgat tttattttag actttattat agactttgtc aataaaaaag
    28561 tacaaaaaat agttacattt ttagttgttt cttgtttact tgttccttga caattgaata
    28621 gagcatgtga gataataaag gggaattaag gattagttct atatcatgga ctagaaaaga
    28681 ccccaggcta acttccacat taagcttggg gtcttttttt gacactattt gtccttgttc
    28741 agccatttat cagctaaacg aagaacgaca ccgaccacaa tcggtccgat gatagtttta
    28801 aggattagtt ccatcatggg ctatctcacc tcctttcgta ggcggtgtag aagtgccgta
    28861 aaatattata ccacatttct aattcagctt gtcaaaggtt tcttttgaca acttaaaata
    28921 gatgtgagat aatatagggg aagtgaagat gtagtctact acaactacaa aaaagcccct
    28981 gctgataacc acaaaagcaa gggctttttc tagtctacgc tagaaaggtg ggttagtcgc
    29041 tatttcttgt ttagccattt ttcgatgact atcaggacga taccgaccac caagggtaga
    29101 ataatatttg tgaagatgta atctaccata ggctccacct cccttctaag gcagatgtgc
    29161 cgtcactatt ataccacatg ctctatcagt tagatagggc attttttatt tttgaaaaaa
    29221 ggaggaacgt gtcgatggta agtattctta aaaatttaga acaagaaaaa gaccaccttg
    29281 aaaaaatcat taaggtagtc agcgctggtg gtaaatttct gagattgcca tatcaaaaaa
    29341 agtcacgctc gattagtgag aatctgaaat tgatttctca aaatcttgat aaattgagcg
    29401 agcaagttca acaaaccacg aatcagcatt catgatttca agatgacgaa agaaacctgt
    29461 tttggtttcc agttcagaat cgtgtgcata acgtaatatt tctctagcaa agatggtttc
    29521 aaaatcaaaa tctttaccat catcgtagat gtcgcgtttg cttgctttga gtaaatattc
    29581 tttaaaagtc ataaggttaa ctcctttctg cttatattat agcagaaaaa gaagaaagaa
    29641 aaagaaagga gaaaatatgc cagatattgc aaacggtcgc gaaagagtta ttgctttctt
    29701 gaaagagaaa ggcattaaaa aagcaactct agcggttgct tacggcttta aacgacagga
    29761 agtgacaaac attctaagtg gaacgactaa aggtccacga gcgaacagtt tcattcttca
    29821 ggttattgaa gattatggga ttgagtagga aagatttgag gagtaggaaa atgagaccaa
    29881 gacgatatcc gtatagtggg aaaaaagagt ccacctttgt aaaggccgac cctgagttag
    29941 ttgaaaaact tttaagaaac actagttttc ttgagtgttt acaaaaaaag cctatcaatt
    30001 ttcagataga cttagaagaa tttaagcgtc ttagctatga agccattcat gatacttctc
    30061 aagtaactca acagtagtta ttacagaagt caaaccactg accttcccca gttgcaatcc
    30121 gtctgtatgg tcaatctgtt tagtagcttc attagcttta gcagagatag cttgcatatc
    30181 ttcagctgtt aaagattctc gaaaatcttt aaaggatttc ataaaaactc ctcctttcta
    30241 ttggaatttt gactaaaacg gtgagaggtc ctagtcgaga ttattatagc aatttaggag
    30301 gatattacat cggtcttgag gctgattttt ggaggcaata ttggaagata aaatcataga
    30361 acttgctgat tacttcatca gcgaatctac aacgtacaga gaagcaaaaa tagcgtgtga
    30421 gaagctattg aaacaagtca gccatgagat agaactcagg gcgatggaaa gtaggacagt
    30481 ctagaagaca acaaaaagca cctgacggaa atcaggcgca tacttaaata ttcaacatga
    30541 ttataacacg aaaggagcaa aaatggaagt agttgaaatt gtaagaatta aagatgtgat
    30601 tattgaaaaa gtctctgcta atgatgaaga gttaaaacgt atctttggat gttcaaaacg
    30661 acaagcagga gagcgaagaa gagaaatgca aaaactccct agtcagcaaa aacatctttt
    30721 ggatagtgga caacttgtaa cgattaaagg tttctatgaa tacttgcaat atcgtggaac
    30781 taaagcttgg aaaaaagaaa tggaaacaag caagaaaatg aggtcagcag gatgaaccta
    30841 ctatcaagaa tcaaaaacta tttttcggaa gaggtcaaag aaactaatct cgactggaaa
    30901 gaggtcgctt tagacctcaa tcaatcacta attgaaacac aggaaaaact tcaagaagcg
    30961 aatcaagaaa tcgcagactt gaagaaaatc gtagcaatct acaaagaaaa ggagaaagaa
    31021 aaatgatgga atacatttac ctggtaataa tcgtaggaat tggactatgg tcgctagtaa
    31081 ataaactaga tgaccacgct gaaatgaaac aaaaagagcg ccagctgatg gcaaacaatg
    31141 tcgcacggat gaatctgaga aattcagata agcaatttac ttatgatgta gaaccgcctg
    31201 aagggttgaa ataaggagga gaaacatgac tcaagcggaa caaattaggg aatattatag
    31261 agagcaccct gctgcctcat gtgatgaagt ggctgaggtt gtcggtacaa caaaaagcaa
    31321 cgtaagtgca aacctggcca aagacatcaa ggcaggcaga tgcgttcgct tggaagacaa
    31381 gtcatacgac tactcccctt actttaatca cacacaagcg ctcactgagt tggttgattg
    31441 gaagaatgat accagacgtg agtgggtgga tatgctgaca agagcagcag agaaagaaac
    31501 ggatagcaac gttatgcgtt tgttaatcaa agaagcaaat aaattgatga aagaggtgac
    31561 taagtagatg gtacgaaata aaataggtga tttaactaac acgctcttcg ctcaattaga
    31621 gactctggat gatagggatc ttacagcaga tgaattaaaa gtagaattac agcgctcgaa
    31681 acaaatggtc gcaatctcag gtcaaatctt acaagcaggt caattggcgc tagatgctga
    31741 aaaattcaaa gacaaggtag gtgaagtcaa tgccccgatc gctttgctgg aaggatgagt
    31801 acacggagta catgcatgaa atatgccctg gtcgtttaac tcctgaagta accaggttgc
    31861 tgaatgaaaa atttggtacg aattataaca agagtcaaat cggtggcgta cgcaaacgtc
    31921 tagggttagc agttggaaaa gtctatcaag gtcgattgct gacaaaggag caacatgatt
    31981 atcttgtatt gatccaaaaa aataagattt ctcgtaatgt cgcaaatgaa atgaaccaaa
    32041 aatttggcgt atcgctaact gagaaacaga ttaagagtta tcggagaaat aataatctac
    32101 atagtgggtt gacgggaaga ttcgagaaag atcagactcc tcacaataag gggaagaagt
    32161 accccaatat gccaaaaaac agcgggcagt tcaaaaaagg taatcgacct ccgaattatg
    32221 tacctgtcgg cactatcaac tacacaacag acggttatcc aaaagaaaag attggagaac
    32281 ctaatcaatg ggttttgaaa catcgtaaag tctgggagga ccatcacggg ctgataccaa
    32341 aagggtactc aatcgttttt ctggacggtg ataaaacaaa ctatgatatt tcaaatctgg
    32401 catgtttatc taagaacgaa attgctagaa tgaatcaaaa tcatttattc acgtccaacg
    32461 ctgatttgac taaatcaggt attggactaa caaaacttac aaataaaatc agagaggtag
    32521 aaaaaaatgg ctagtttata cgaactaaca ggtcagttcc tgacaattta ccaattggat
    32581 atcgatgacg aaacaaaagc agacacgctt gaggccatcg attggcaaga acaatttgaa
    32641 cagaaagcag aaggatatgc ccatgttatc aagaatctag aagccgacgt ggccatgtac
    32701 aaagctgagg aagagagctt caaagccaag aaacaagcgg cacagaaaaa gctggattat
    32761 gtcaaggata acattatggc agctatgaat gtcacaggtc aaaccgaagt caagagtggt
    32821 gccctgatta taaaaattgc taaaaatcca gaatcagtca aggtcaacga aaatgacctt
    32881 ccgaaaaaat attttacaaa aaaagtgacg cttgcgccgg acaaaaaaac actcaaagag
    32941 ttgcttaaat ctggcaagaa agtcaaagga gccgagctca ttagaacgga aaagttggtg
    33001 attaagtaat ggaattgatg aataaaacac gagtaacaga ttcactagca gttgtgattg
    33061 gactagaatc gattgaagta cttgttactg aaggttttct atttgatgtt gcgattcgtt
    33121 ttgtaaaagt agacgaaaca aatcttgatc aaggaaatga aaagccagta ttcactccgg
    33181 aatacaagct ggtcacagtt gctaaataca aggaaaaacc tatctttgaa tcggaggaag
    33241 atattcgaaa atttgagaag caagcaaaag aagttaaatc gctatttgcc tttgcaaagg
    33301 taaataaaca aaattggttt aacactgccc tttatccagg agtgctgact gagaaagttg
    33361 gtgtttgatg aaaattttag ctattgatcc aagcagtaat aaaattgaaa ccagcacaac
    33421 aggagttgtc ttgttggata atgcaagatt agttgatagc tgggttgtct cttatggtat
    33481 gagaggtttc gctgattggt ttcacgaaat cggaacaaat cttgaattcg atgtagttat
    33541 tgttgaagaa tttaaggcga gggataacga aaagtcaaaa gataatagcg tggcagaaac
    33601 catcgcttat atccagcttt gttatccaga ggctattctt caatttaatg caggttacaa
    33661 gtcggatatt ccaaacgatc ttttgaaaat cttagacctt tggaaatttg aaaaaagtca
    33721 tcatcaagat attagagcag cagcaagact tggattattt tgggcaatga gaaatgatat
    33781 tgaagaagtg gttcatgata tcggaaaggt ggtgagtgag tatcacaata acgctaagaa
    33841 agtggcaagc tgaagcgatt aaaagaagtg aacatttatc taatggaatc tttttagagg
    33901 ctcttggggg cagaggcaaa actatctgtg cacttgctat tgcaaaacat aaaaaagcta
    33961 aaaaaatcat catcacaaac aatcgactag ctattctgaa tggttggata gatgcagtca
    34021 agtttatgaa ttttgataaa ggtgttgaga ttatcattca gacagataga tatcttcaaa
    34081 atcaagtcaa aaaggggcat aaattagatt gtgatgtgct gatagtagac gaatggcaga
    34141 atatgtcttc tgacaaacaa gtggccttat atcgcaaaat aaagcgaaaa tacacgatag
    34201 gtctttcagc gacaccaatt cggaaaaaag gacaaaattt ctatccgctt gaaaaaacgg
    34261 tatttggttg ggcaacccca aataataaat ttgactggca aaagactcat ggaaaaatgg
    34321 tctatgatcc atttagctat tcaaaagaga agtgggaaga ttttcaaaat tatgaaagtt
    34381 atatctcgag cttgcctaat ttcttccgct gggaagagat tgaaggaatt gagaatgcag
    34441 ttgagaataa cggttttgag attaagtttt accaaaagag agtcgcctct ggcaatccag
    34501 aaaaacttgc agaatttaga aaactaaatc ttgtaacagt ggacggcaaa actgcaatgg
    34561 ccaagcaatc gtttggaaga aagacctttg aacgctacct taatcaaaca ggcgtagcag
    34621 tcgattttcc aaaattaaag ccagtaaatg cggatacgcc attgatgtta caacttgacg
    34681 gtttaatcga acgagcacca cacgatatgt tgattgtcag taaatctaag cagattgtca
    34741 acgtcattag cgagcgccat cctgaaattg gaatctggac gggcgatatt caagaaggac
    34801 tttataagaa attcgtggtt gctactagtc aagtgttagg tgtcggagta gacggcttgc
    34861 aacacaaata ccaaactatt gtcgtattgg atccagtaga agaaggttct ggagaatatg
    34921 atgattatcg acaattgctc tggcgcataa caggaagtcg tcagcagcat gatgtaaatg
    34981 taattgaatt ttattataaa gaaagttaaa aaaaagagga aaacaaaatg aataaaacaa
    35041 ctgaaatgat cgtatttcgt agccgtaaaa ctggagaatt tcttaattct tacaaggaca
    35101 gaagttcttt agcatttgca gctgactttt gcagcttgga atattgtttg aagcttcctc
    35161 gtaaaaaata cgaagacaac aaaaagactt acaaggctct tgctgcagct tttgactgtg
    35221 aaattgtcgc agttgaagcg gaatacaaat tgacctatcc gaatggatca gaagttgaac
    35281 ctatcaagcg tgaccgttca tcaattgagg acatgattaa ggatattatt ggaggggttc
    35341 tctaatggca tttacacttc cagcaaataa accacaagtt cctaaagata ccccacgaaa
    35401 ttttttcatc tacggtgaaa ccatgagcgg aaagtcttat cttgcaaatg aattcccaaa
    35461 tccaatcgtt ttgaacacag acgggaatgc agaagctaac actgttccaa gcattcagct
    35521 gatcaatgaa aaagatgaca agggacgaat taccaattca gtaattaagc agcttggaga
    35581 tatcttgctt gctctccaga cacagaagca ctcttatgaa acagtcgtta ttgatgtaat
    35641 tgacgatgtt attgaaatga ttaagattgc agtttgtgat gaattaaccc cagttggtaa
    35701 acctcgcttg aaatccttgt cggaaattcc atacggcaaa ggatacgact tctttaacca
    35761 agctatcaca gaattagtca ttgacctcaa agcattgcca atgaatgtta tttacatcag
    35821 ccgtcaggta tctgaatatg atgacaatgg caatgccacc aaagacaaac caagcttgaa
    35881 agataagtat gtcaatctta tcaatggaaa ctctgatttg atgatccaca ctgaaaaact
    35941 cggcaacaac tacaaccgtg aggttgaccg caagcgtaag acctactatg tgaaccatgt
    36001 tgatgacaag gctattttga aaatcttagc aactatccgt ggggctgttg aacctgcaaa
    36061 aaccgaaaag acaaaagagg cgcctaagaa agaagttgcc tctgatgatg aactatttta
    36121 agaaataaag gagaatacac atgagcttac tagatatcgc aaaatcaatc aaaaaagagg
    36181 gctttgaccc acgcaaagac agcgccaacg gtcctgcacc aatcccagct ggtacttatc
    36241 cagtagtcct gaagaaagca actttcaacg tatcggacaa aggctgggaa agccttggtt
    36301 atcaatttga aatccgtggc ggtgattaca gtggacgctc tgaatttgca acatttggca
    36361 cactgactga atggaacggt aaggacctta actgggcagt tgaacgcacc atgaaattct
    36421 ttatcaaagc cttggtcctt gctggcgaca gtatgcaagg aaatgaagaa gacggtaaag
    36481 ccttggaaga ggctctaaaa cgtaaggcag ttggctctta ctacaacctt gttatctctg
    36541 tgactaaggg gaaagatggc cgtgagttcc gaaactatga ccttgaagaa gaagcacaac
    36601 cgctgactga agctgatatt gatgacgatg acctcccttt ttaagaaata acaagttctg
    36661 ggtcattgat gaaactgatg aaagattagg accattcaat acatttgaag aggcttatca
    36721 atcgttgtta ttttatttaa aaatgactga agatgaatat caatcaaatt atatggccca
    36781 agaacttgtt tatatttaca aaaaggagaa gtaatcatgt cgtcgatgaa agaatacgca
    36841 ttacagtacc aaaagttagg gttctcagtc attccaatca atcctaaaaa caagatgcct
    36901 ttgattgatt ttgctgataa gccagccatg actccatctg agattgaaaa cttttgggac
    36961 ggctacccta atgcaaacat tgccctaaag attaccaact tctttgtcat tgatattgac
    37021 aaacacggca aatcgaacgg ttttgaatcg ctaaaaaaat ggaaacatct aaatttaatc
    37081 gaaccgacac tgcaagctaa gacggctagt ggcggtaaac atctattcta cttcaaacga
    37141 gaagatgagc cgatcactca gatgattgga ttcttgcctg gtgttgatat taaggctcac
    37201 gaaaataatt atgtgttagt cgcaccctct gccacagata aagggcagta tgagtgggat
    37261 ctggaaaagt ctaaggaagg tggcacgatg gtcactcctt caaaagattt aatccagtct
    37321 ataaaaaaac agtatggcga aactcacggt tataagtatg atggtaagga cggtcttagg
    37381 gatttagtta gacgttcaca tactagagac cgaacacaga ctacagatct ctttgaaacc
    37441 atcgcccttg gttttggtga tgaaggtgga cgaaatgaca aactagcaaa attcgtaggt
    37501 ggtctcttat atcgtgcggt cgacgatggt gtagttgttc aacttgcaag attagcaaat
    37561 gcaaatagtc caaacccttt gcctgaaaag gaaatgatgc gtactattga aagtatgatt
    37621 aaaaaagata ggaggtgatt gtgattggta atgtagtaag tattgactca caacctaaga
    37681 tgataacgac tgccaaggga gacatcaagg ccaacagtcc aagtaatgtg ttgatgtctt
    37741 tcaaagctga tgatcagttg agtatttacc taaagcacaa cgatttttcc caagagcatg
    37801 aactccttaa agatatcaag atcggcaaca ctctttttaa aaaaggtgag ctcccttcta
    37861 actttgattc agtcgtaaaa gtttactttg aaagtgtgtt aggtgttgct ttctcaaacc
    37921 aagcgatgct tgatggcatg gagactttct tttcagaaag atcatacaat ccagttattg
    37981 agtatatgga gagagcaact gaaaagtggg acggcagaaa ccggattgac cgcatgcttc
    38041 aagtatatct cggcgctgaa gatatccctt tagtttctaa aatcgctcaa atgtggctag
    38101 ttggtgcagt tgctaaagtt tatgatccat acgttaagtt tgactatgtt ctggacctgg
    38161 tcggtggaca aggagttggg aaaacgtccc tccttcaaaa attgggtggc gaatggtata
    38221 cggatgccgt aacagatttc tctaataaag ataattacga cattatgtta aagagtctaa
    38281 tcgtcaacga tgatgaaatg gtggccagta atcggatgag ctttgcagaa actaaggcct
    38341 ttatttctaa aactagccta cgttatcgta aaccatacat gaaacgaaca gaagaatttg
    38401 ccaagaactt catcttagcc aggactacta atcaaaaaga atacctcaag gacaaaaccg
    38461 gtgaacgtcg atttctcccg attatggcag atagcaagca acaaaagaaa catccaatgg
    38521 aaatcgatcc tgatacaatc gaacaaattt ggggcgaagc cgttacaatc tatcgtgctg
    38581 gtgctgattt gatgtttgat gaaaatacag aggatgaact gaatatctac cgtgaacagt
    38641 tcatgtatcg tgatgaagtt gaattacaag tgcttgaata tcttgatatg cccgtccctg
    38701 aaaattggca aaactggtct attcagcaac aacatcaata cacaagtaaa tatttcgata
    38761 atagtagcga ctttgatcct ggaagcaaaa aactagataa ggtctcaact cgtgaaatga
    38821 tgtacaactt atttatgaga aattcgaatg acaggaagct gtcaacgaag attaacatga
    38881 tcatggataa tcatcctgat tggaaaaaaa gtgttttccg ggcaggaggt aaaaatacaa
    38941 aagggttcgt aagagtgaag aattcggaaa aaactaatcg gtagcaatta aaaaattatt
    39001 ggtagtcatc ggtagcagtt gagggggaga tcggtagcat tctaccgata aaataggaca
    39061 tcggtagcac atcggtagca gtctaacccc ttgatattac tgacttttat ttaatattta
    39121 tatataatgc tactcttcta cctatatttt taaaaaaagt atataaaata atagtaataa
    39181 taaagaaagc ctatagaata gggattcttg aaaaaaactt tttacttttt agaatttatc
    39241 ggtagcacgg tagcagttta gaaaaaagag gtaaaaatgt catacacagt aacattattt
    39301 tttgacaaca tggtagacga aactcacttt tttaagaaag agagtgatgc tgccaaatgc
    39361 aaggctcagt tagaaagcaa gtatcgaggg aatcgaatgt ataaagtaaa gatggaggag
    39421 atggagtaat gagttatgat ttggaaatct tagcgaaaat agagagtgga gattatattt
    39481 gtattgctga acctagatat agttctccga cctacaatct tggaaaaatg tttagggtgg
    39541 ctatggattg ggatttcgac caaggcacaa tttacaatgt tgctgatatt tttgaaaata
    39601 ttaaacgtgg cataactgaa ttggaaaggc aacctgaaaa atatgtacaa tatgaacctg
    39661 caaataaatg gggaacgatc aatgatgcgt tatatgtttt gagatcgtta agggactgta
    39721 ttttagaaca agatattgat acgaaatatt tatatgtgag gtggtaaatt gaaacgacca
    39781 aacagatacc cgtacactaa aaatcaatgg gttgaagaaa ccgttgatca ctatacttat
    39841 aaaaacgata tttgctatac aagtcacatt ttagaaaata gacttactgg agaaattaag
    39901 gacaaggagt tgaagtgatg gaagagttaa agcgaaaagt taatacagta tacaactgga
    39961 cggtagaaga cgggaagccg caacctccca agcaagattt accacaagtg gtgaaagacc
    40021 gggcggacta tttttgggaa atggcagaag atggtatgac gtttatggga gcgatggaat
    40081 gcatcttcgc tgatgaaaag cctacagact atgatttggg agctactaag gattggttgc
    40141 caaaatctaa ggagtttgat gattgggttg gttattcgcc aagcatggct caggtagtta
    40201 ttgcagttta tttgatttat agaggaaact aagatgaata agcaggaatt gattaaaaaa
    40261 ttagaggaac gaagaacaat aactgggaat tttcaaggtt atgtagtttg gtggaaggat
    40321 gtaaaagaaa tctttgaaca actaggcgaa ccgcaaccag tcaaagtacc gcagtttgtg
    40381 gcggattgga ttagaaaatg taaaatgttt aagcattttg ctgtaagtct atcttttgca
    40441 ttacaaccca ttgtatggga agaaaatggg ttatctcacg agtgcattga atggttgatg
    40501 gatgcaaaca atcaagaact cttcgcacta gcttggctta acggctacga ggtcgaaaaa
    40561 gagaagcggt attttgttaa gattaaaggg aatattaaag aaaatatgtt ggtttatgga
    40621 gaacttttga aaaggtattt ctttacaaaa agctttagtt tagacgatgt tatatattcc
    40681 cacacccgta aagaactaga agacgcaaac ttcggctggg tgtttgattg tgaaggaatt
    40741 gatatagagg aggtggagtg atggaagatg aggaaatcat aggcaacatc tacgcaaacc
    40801 cagagctttt ggaggtcaac gagtgagata ttttaaaatc ctatgtattg ttttattcgc
    40861 atccttactc gtagcatgtc accagatttc gagtgggaca gtggtagata agtacattga
    40921 tgaacctcac acaacgttca tacctgttat aaatggtaaa agttcggtac ttgtgccaac
    40981 cagaaccaaa agaaaataca ttctggtcgt ttcaggatat gcaggtaata agcaagttga
    41041 agaaaggttt gaagtgacag caaatgaata caagcactat gaaattggca atacttttat
    41101 acaggatgcc gttttagaaa ataaggagga ggataaataa tgagacctaa aaaataccca
    41161 caagatactc aatagctact aaaacaaaaa aagccaagac actctctgtc tcagcaataa
    41221 tctcaataat attattatat cacaaaggag acagagagtg aacaaggcta aagaactatt
    41281 gaaagagttg cagaatctgg acatggacat tcaaagccgt atagatgaaa ttaacgagct
    41341 tgaggcaggt ttgctttcaa gccccaagtg gattgacgtc aaagtccaag gtggtcaagc
    41401 tagaaaagtt gatgatgtct atactcagct tgtcgtgatg aaagaggcta tagaacagga
    41461 tactaaagag gttatcaaca gaaagcttga gcttggtagg ttgattaaca agctgaaaaa
    41521 tccaaagagc aggtctattc tcagggtgac ttacattact aagatgtatg ttgatgatat
    41581 ttgtgacaaa atggaaatca gcagaacaac tttctacact tggcggaata tggctatctc
    41641 tgaactgaat gaggttttgg agagaatgga actaaattga actttacaaa accgtacggg
    41701 aaaaaatgat acttgttagc acagttttgt aattctgata aaatggtagt atcaagaatt
    41761 gaaaagagag gtctcagaat tggtagatgg ttacctgtaa tgtcaggggg ctgtaatggc
    41821 cttggaggtt caagtcctcc cctctccttt gagtgtttgt gtcccagaat gagttaaatc
    41881 ttctgggtgg ggattcacat atcactcatt aacttctatc actcattaac ttaaaaatgg
    41941 ttgcagtagc gactgaacct tgcatgattg cgtagctaat tatattccgg ataagttata
    42001 agctagaggg tttgattccc tcagaggttg taaagactac aaaaaataaa aatgaagtca
    42061 aaatttaata cgcacgcaag gtagtagtcg ccttgcactt ttagggctta gcctagataa
    42121 tctgtggtaa ctaaggaaaa ggatgttttt aaatctatca aacatcctgc cagcaatggt
    42181 caatctaagc aatgtaatct taactatttc agttttggaa taggtaggcg aagttaaagc
    42241 aggaagattc caacggcaag gtgctgagga aatgcaaatg tggcagtttg gctgtgagac
    42301 gagtctataa gaggaatgag gtattcggtt tgaggtgcaa caagagctta ataccatatc
    42361 ttacaaaaat tgggcgcctc ccaaaagtat gtaaggtgag tcgattgtcc gcaaaacaat
    42421 cgataacaag caggcgctgt gcattttgtt cttcaaaaga gaatgaaaca catggcgatg
    42481 cgtgtctgtg atagatgaaa gatgattttt atattttaag gctattcaag atagaaaaaa
    42541 ctcaaaaaag caaaagtcat cgcccgtcgt aaacgaaagt gcacttcggc aattagattg
    42601 cctgctcaag tctcgcaagg atgagagtaa agtcaaagag taaagcagct tagactttta
    42661 gcggagtctt cgttaattga aaaatggcct agtagtttgc gatgtgagga gtgattggtc
    42721 taaccaatcg tgcatgagtg atacaagtag gaatatttgt ggacaagata ataaactata
    42781 agttatcaaa agtcactcgt ttaaagcagt agtctcatgc tagttaatgg atacatggta
    42841 gacggattaa gtcctgttta gggaattgaa acgtaggcag gttcgaatcc tgtcgttcca
    42901 attgcgattt taattcgcag agagaggtct tgaaaaggtc gcacatcgtg tggctttttt
    42961 tgattgtttg aaaggtggtg atggaaaatt gaatgaaaga caaaggcgtt ttgcagatga
    43021 gtacatcatc tcaggtaatg cttatcaatc agctttaaga gcaggatata gtgagaaata
    43081 tgccaaagca agatcttctg aattgttgga taatgtcgga atttctgatt acatcaaaaa
    43141 tcgaatggag gagttgcaag atgaaaaaat cttaactcaa aaacaaatac ttgtgatgct
    43201 atcagaaatt gcgtcgggac aagcgaaaga aacaatagta gtcacaacaa aagtagctga
    43261 gttgatgact gatcccgtga ctggtaagtc tgtaaaagtc tacaatgaaa tccctcaact
    43321 tgtcgaatac ccaacaaaga acagcgatag gaataaagct cttgaattgt taggtaaacg
    43381 acataagatg tggacagaca aagtagaggc agacgtttct ggaacggtgg tgtttgcaaa
    43441 tgagtcagac atatcagatt aaacagaacg atattgttgt tgacctacct aagacagtag
    43501 gagctggata cggacagttc tggcgctcaa gaagtcttta tcgtgtagtc aaagggtccc
    43561 gtggttcgaa gaagtccaag acaaccgctt tgaattatgt tatccgtctt ttgaagtatc
    43621 cctgggccaa cttgcttgtt attcgtagat actcgaatac caacaagcaa tcaacttata
    43681 cggattttaa atgggcgtgt aatgtgttgg gtgtgactca tttgtttaaa tttaacgagt
    43741 ctttgcctga aataaccata aaagcgactg gtcaaaaaat cctattccgt ggtttggatg
    43801 atgaactcaa aatcacatct atcacggtcg atgtcggcag tctttgttgg gcatggtttg
    43861 aggaagcata tcaaattgag actgaagaca agttcagtac agtagttgag tcaatccgtg
    43921 gtagcttaga tgtacctgat ttctttaaac aaatcacagt cacatttaac ccgtggaatg
    43981 agaggcactg gctcaaacgt gtgttctttg atgaagagac tagccgagct gatacattcg
    44041 ctactacaac cacttacaaa tgcaatgagt ggcttgatga agtcgatatt aagcgctatg
    44101 aggacttgta tcacacaaat ccaaggcgtg cgagaatcgt ttgtgatggt gaatggggag
    44161 ttgctgaagg tttaatctat gagaacgtga ccgtcaagga tttcgataag gatgaattgc
    44221 tacgagattc agctaataag ttatgtatcg gtcttgactt tggttttact cacgatccaa
    44281 ccgctttgtg ttgttcgttg ataaatgaca cgacgaaaga gatttatgtc tttgatgagg
    44341 cgtataaagt tgggttgata acaaaagaag ttgcgaagat gataaaagac aaaggttatc
    44401 atcgttcaca aatcgttgcc gatagtgctg aattgcgact gattgaggaa ctaaggtcag
    44461 agcatggtat aactcgaatt aaagagagtc gtaaaggtaa ggatagtatt atggcaggcg
    44521 tatccaaatt gcaaggatac gctatttatg tgcatccaga ttgtaaaaac atcatggatg
    44581 aattttatag ttactgctac cagcgagata aagaaggcaa ctggttgaat aaaccagagg
    44641 ataaaaacaa ccacttgatg gacgctttgc gttacagcct tcaatgtatc gaaggtggaa
    44701 aagcaaccgt ccgcagacgt tctgattatg gtctatagag aggaaagaca tgtaccaata
    44761 tttaacctat ccacgggatg gatatgatga gggttctttg aagaaagacc tgatttacaa
    44821 attgataacg atacataaca ctgaaagctc acgcttgaag aatttaaaaa gctactacat
    44881 gggtgatcat gctattttaa atcacaagag acgcaacgtg aacgcaccga attacaagac
    44941 ggtagctaat catgccaagg atatcgcaga cacggctaca ggctatttta tgggcaatcc
    45001 tattaagtat aacaatactg ctgacagtga tatcgatgaa ctacttacag cctttgatgg
    45061 tgctgagatt gaccaagtag atgctcagaa tgctttgaac atggctatct atggtcgtgc
    45121 ttacgagtac atctatgcta aagagggtat gactgagttg gattcaacta gtattgatcc
    45181 agaaaatacc ttcatggtct acgatgatag tattgagcgg aagcctttgt ttgcggtcta
    45241 ttactatgaa gtaaaagacg atacgaaaga cactaccaag taccaggctg aggtctttac
    45301 cgaaaatctg cactatcaca tggtgctgag aagtacagat tcaggaacaa ctcagaatga
    45361 gcaggtaacc cctcacaacc ttgggcaaat cccaattatc gaatatcgca acaatcactt
    45421 tgcgatcggt gactatgagc aacaaattag cttgatagac gcttataatt ccttgatggg
    45481 gaatcgtgtc aatgataagg aacaggctgt agagtctatc cttgtcttgt atggcacgca
    45541 gttagcagac actccagaag acgctaaggt agcgatgaag attctttctg aagaaggtct
    45601 tttggaatta ccgggcgata gtgcaagagc tgagttcttg aagaacacgt tggacgaaag
    45661 tgctactgaa atcttgcgta cagctcttaa agaggacatc tacacattta gccatgtgcc
    45721 taatttgact gatgagaatt tcgcagggaa tacatcaggc gtagccatgg aatttaagct
    45781 gatgggcctt gagatgatta ctaagaccaa ggaagcgaac tataagcgag gattgcgtca
    45841 gcgtattgcg atttttgctc attacttggg tatgaaacag attgcactag agtctcattc
    45901 aatcgttcca caattcagtc gtggtttgcc taagaacttg ttagaaatct ctcagatcgt
    45961 gaacaacctt gaaggtaaag tgacgaatag acagcttatt tctctcttgc cgtttgtgga
    46021 agaccctgac gctgaactgg aagccttgga agaagaaaaa aagaagaaca tggaagacat
    46081 gccgatgttc aacaaagaca acacgaaacc cgaagacgag gtagaggatg aagaatcagg
    46141 agtattgggc gaagaggaaa gccaatctga tttaccagca gatggacaag gccgaaaagc
    46201 aggcagacca gttcgataag gtctatcagg aagccaagac ttacttggat aaggaagtca
    46261 ataagatttt tgataagttc caacgtgatt atggtctaag tcaggtagaa gctagacaag
    46321 tcttgaagaa catgaaagac aagaaaaatc tgaatgaact tcgtaaagtg cttgaagcaa
    46381 gaccgaatga tccaaatatt caaagactac tggctgactt agatagtccg gcttattctt
    46441 tccgtatgaa gcgtctagaa cgtttgagtg atgatttaga ccgtatgcgt gaatctatct
    46501 atcattcaga aaagacaggc tcagacgcct tttatagcga cctgatgaag gatagttact
    46561 acaaggctac ctttgacctg cagcagcaga caggactagc atacggcttt tctgggcttc
    46621 ctgagagcga gattaaacat ctacagtctt tcagttgggt aggtgacgga agtacctact
    46681 ctacagacat ctggaagaat acggggaagc ttacttctag cataaaagat gaactactta
    46741 tgagcctcat gacaggccga gatacacgag aaactgcaca agcaattgct gagaggttca
    46801 atgtaggtca gaatgatgca aggcgtttgg ttcggacgga atcagccttt tttcataacc
    46861 aaatggaact actcagctat gaagaagcag acatagaaaa gtatatcttt gtggccgtct
    46921 tagacaagcg cacatcacgc atttgtcaag aacatgacaa tcaggtctat gatagggata
    46981 aggctgtccc tggtgtcaat tgtccaccta tgcacccttg gtgtaggtct actactgtcg
    47041 catacgacga ggacgcagac tacagcaagt tgaagcgcag agcaaggaat ccagtgacag
    47101 gtaagaccga gctggtgcct gctgatatga cttataaaga gtggtatagc aagtatgttg
    47161 cgaaagacgg ggaaaaggtg tataatcaag atacaagaga agccaaggcg aaattttata
    47221 gcgaacaact attgtccaaa atttcaggag ttgagccaaa aattacaagt gatatgcaac
    47281 gtatcgcagg agaaaacaaa ttggcaggtc ttgaatttag gaagaaaaca gttgagtcgt
    47341 tatcacgtaa aattattgca gatagcctag ttgaaaatat aagtttgtca aaagccgtga
    47401 gtaagattaa tgacgcctta aggtacacaa ctattttcga ttccgatact tttacagaag
    47461 agtatttgaa gatgaaacag aagcttgtcg cagaaggtta taaaattgta aaagtaaaaa
    47521 acacttggtt agtagatgga ccatacaaag gtgtgaatac agtcgttgaa aaagatggta
    47581 tcaactttga aatgcagtat catactcagg aaagtttcga cttaaaaaat ggttcattac
    47641 atgaactcta tgagaagtat cgtgatacga atacatctga tctagaacgc atgaaattat
    47701 ttaaggaaat gcttgattta agcaatgggc ttgagattcc taaaaatata gagagggtga
    47761 agtgatgtga aagatattaa atactaccgc acaacgacga acaatgctca agtacttcgt
    47821 ttgattgatg gtgtcatgca agtttttgac attgaaaaaa agtgggttaa tagcatagat
    47881 tggtttaata aaatcttttt taatgacttt acggattttg aagaaatttc agaaaatgat
    47941 gcatttactt atattgacag gatggtagcg gcatgattga tattgctttg gctatcgcta
    48001 aaaaagcaca tgcagggcag gtagataaag cggatgttga ttacatacag catcctctct
    48061 atgtggccag tcaagtcaaa actgaacaag aaaaagctgt cgctctttta catgatgtga
    48121 ttgaggatag cgatataact gctgccgatt tattggcgtc tggtttgtca aatgaagttg
    48181 ttacagcggt acaaattttg acaaagaaaa aaggtcaaag ttatcaagaa tatcttggga
    48241 aagtaaaatc aaataattta gcaagagttg taaaacttgc agatttgaaa cacaactcag
    48301 atttatcacg tttgaaatct gttaccaata cagactacga gcgtgttaaa aaatataaaa
    48361 atgcaattta ttacttaagc acctagagaa atctaagtgc ttttttcgta cccagaaagg
    48421 attgaaaatg gataaagcaa aaattgggat aactaacgta gaattttcag gaacaggcgg
    48481 aattgaatca gcgacagtga aattagagtt aaatatttat ggggcggata cgttcagcgc
    48541 gattgagtta ctacctaaaa tattaaccga cattcattca ttatcgtatg aagttgattg
    48601 attgtgacat taaaaggagt aagatatgtt tatatgggat tgggtatcaa tcgctttcgg
    48661 gtggttggta tttttgtttt tgatgctgat tatcatagca tttgtaaaaa aagtgattga
    48721 agaaaataca aaataatcta accgtatgga atcccgtacg gtttttatat tgtccaaact
    48781 gtgccgatga cattaaaagc tgcactgttc cgtcgccgga cgtaaagcga gattatcgag
    48841 tggcgacgta atcgctggag gacaattatg tcagaagaaa tcaatgcaac tgtatctact
    48901 gaatcaactg agactgtcga cactcaagga aatgttgatt cagtgcagga agaaaagcac
    48961 gaacgaactt tcactcgtgc tgaaatcggt aagatgctat ctgccgagcg ctctaaatgg
    49021 gaagctgagc aagaagccaa ggaaaacgaa gctaagaagc ttgctaagat gaacgctgat
    49081 gaaaaacaga aatatcagtt ggatcagcgt gagcaagaac tagctgaccg tgaaaaggct
    49141 attgctcgta aggaattgac cgcagaggct aaagcaatgc taagtgaacg tgacttacct
    49201 gttgagttag taaatgtagt cgatttgaca aacgcagaga cggtatctga atctatcacc
    49261 tctatccaaa aagcatggga agagtcagtt cagaagggag tctctgaacg tatgaaaggt
    49321 agtgcaccta tcaaaaatgc acaaacagtc cagcaagaag tcacggaaaa atggcgtaaa
    49381 gacttcttgt aataaaagaa aagaggaaaa ataaatggca tttgaagaat taaacacagc
    49441 agaatcacgc aagaaacatc ttgggattat tgaggatgta cttgcagtaa attcatattc
    49501 aacaccactt gtgacatcaa gcgatgcagt aaccttgcaa ggtcgctctt ttacagtagc
    49561 aactggtaac acaacagagt tgaaagacta caaacgtaac aaagacaacg aatttgatca
    49621 cgttgaagtt gaagaaaagg tttataccct tgatgaagaa aaatactggg gtcgtttcgt
    49681 agatcaattg gacgaacgtg actctaatgg tcaagtgaat atcaattatg ttattgcccg
    49741 tcaagcggca gaagtagtag ctccatatct tgatgaacta cgttttagtg cagcgcttgg
    49801 taatgttagc gacaacgtta ctatgggcaa agaagcagga gcgaacaacg catacaacgc
    49861 aattcttgat gtttctgaga aacttgatga gcttggaatt acaaaagagc gcttgctttt
    49921 tgtaacacct aaattctaca aagcgatcaa gtctgaaatc gttcgtctac cacatggtga
    49981 cgcagataag aaagtccttg gaaaaggata tgttggtgaa ttggatgatt acacagtcta
    50041 taaagttcct tctaaattct tgaaaggtgt taatgccctt gctactgctc caggtgttgt
    50101 tacatctcca gtacaagtag acaatactaa gtacaacgat aacattccag gtcgatttgg
    50161 tgaattggta gagcaattac tttacactgg tgcatttgtg cttgaacact tcaaaaaata
    50221 catcatcaca attgcagatt ctaagcctgc tgctaaaaaa tcagcccaag gcaagacagt
    50281 gaaccgtgct aaagcgtgga agactggaac agcctataaa gaaggtgata cagtaacgca
    50341 tgaagataaa gtctatgttg ctatcaaaga catcactagc tcaaccaatg caccaggctc
    50401 tgactcagct aactggaaag aaaaaactgg taagaaatag gtcttagtta tgaaatttaa
    50461 aatcaaacaa gatttctatg attgggaatc aaatgtgaaa cgactggcag gagaggaact
    50521 tgagattact gaggagcgct atgctgagct ggctgacaat attgccagca acggtgtcgc
    50581 tatctcagat gttcttgaga aaatcctccc tgaacctgag ttcttagaag aggattgata
    50641 tgtctataga gttgctgaag aaattaacag gcgaagaaga tactcagctt ctcatgttgt
    50701 tccaaacaag ggctacaaat cttatcttgt cagagactaa tcgcacatct ttgacacctg
    50761 ctttaagtct tttaatacct gaggttgcta tcgagctcca caaccgctca ggagcggaag
    50821 gagagcgttc tagaaccgaa ggtggtatag cagtagtcta cggagaaaat ggcctgtcta
    50881 cgggtcttct acagcgaata cgcatgcaca ggctagcaag ggtggcaggt catgtttttg
    50941 aagcagagta gactgaaacc ttatccaatg cgacggtttg aaaagactgt cactgaggaa
    51001 ggtgtcgcga aagaagggta tgccaaggaa gctgagacag tccgccttga attgtggcca
    51061 gctagtagca agttacaatc tgaattgtat ggcgagcgtg tcaatgatat tttgaacgca
    51121 aatgccaaca agtcagctac tatcaaagtg aaagatggtg tgtgtatcga tagccagaca
    51181 gaagtgactc acagggttat ttctaaaaag gtctacacac atcatcaagt tttggagtta
    51241 gagcgtgtca gggctactag gggcagatag gcttatagct aaatgtagac gattggctag
    51301 taaaaaaact ggcgaggata tcgtcttacg tgcggtacac aatgctacta taaaggttgt
    51361 ccaagcagat gcaagaagac tcgcaccagc gagagatgga gagcttataa ttagtatcaa
    51421 aactagagca aaaatggacg gagataaggc tataggcgaa gtttacacca accttaaata
    51481 cgctccttac gttgagtttg gaacaggacc aataggacaa gctaaccatt cgggtatctc
    51541 tccagaggtc agcgtgactt acaagtctaa tccttggtat gtgcatgaag accaaataaa
    51601 tgtaggaccg taccactttc aaaagattgg ggagttctac aagatgtatg gtcaacctgc
    51661 ccagccttat ctttatccag ctttgagaga caatcaagag cgtgtgtcta agaatatttc
    51721 gaattatgtc cgtagaaaga taagagaaca aataaaatga ttaatatcaa gcctgttatt
    51781 tataaagaat tgcaaaaggt tgcagataat gtgaccgata cttatcctag cgattgggag
    51841 actttcccag tcgttatttt tttagaagaa caaaacaagc cgggtgattg gtttgatgac
    51901 caggaacaaa aatcatctat ccgctataag gtggatatct ttgatgatac cagcactagt
    51961 gagttagctg ttaaaatcaa tcagattttt gagtctttag gtttgcgaag aactgactgc
    52021 caagacgtgc cagacccgtc tcatttgaga cataaggtca tgcgttttga aggtgtcgtt
    52081 gatttagact cagagcttgt ttttcaattt agaatggaga attaaacatg ttagcaaatg
    52141 gaattaaatt ggcctttagt gaaacgaaag gcaattatca gaatcttgta gggcttaagg
    52201 aagtacctga atttggtatc gagcccgaaa aagtagaaaa tactactctt gcagatacgg
    52261 tgaagaagta cgagtttggt atcggggacg caggagaact tgagtacaag ttcgcttata
    52321 ataattcaag cgcaacagct ccttaccgtg tattacgtaa ggcagcagat ggcaagaaaa
    52381 aactctactt tgaacaaacc tacccagacg gtactaaggt cacttttgaa ggtcaagtat
    52441 ccgttaaact gggcggtggc ggcgttaatg ccgttatcga gttcacactt aagattgcat
    52501 tgcagtctga attgacattc gttgatggaa ttggaggtta attaaatggc gttaaaatac
    52561 acaacttgga aagttactga cgaaaaagag ttgaagctac gtttgacatc tcatcaagct
    52621 gcaactgtgg aagaaaaaat cggcatgaac ttgttaaaga ttttcatgcc tgaagctggc
    52681 gaagagttca ctttaccgcc tttgaaagtt atgctgttgt tagttcatgg agccttgcag
    52741 cagtatgaac atgggtattc ctttgaagat gtctacgacc tatacgatga atacgtggat
    52801 aacggcggag accaaacgac attcatgaca gaggtgttga tgccgctatt tgaagtatcg
    52861 ggttttactc cacgaggaag caaggacaag aaaacttcca agaagaaaat gacagtagtc
    52921 gagtaatctt aacggtaacg cagattattg agaggcttta tcctatgttt ttagacatcg
    52981 ggggcaagcc tcttgatttt tgggatttaa cggtgcttga aatcagggaa atgatagaaa
    53041 gctacaaccg tgtcaaaatc caagagcgta aagaaaagat tattgactcg tacatacttt
    53101 cgcgaatgat aactaatcat gtttccttat tactgtccaa tgacgctaag attgttgagc
    53161 tttgggaata tgcgcctgag ttgtttgtag aagaacagca agcagtagaa caggaacgac
    53221 agagacaagc gcttttgttg cataaggaac ggatgcgtga ttttgcagag agacataatc
    53281 gaaaaaggaa ggaggaagta aatggcaact cttgatgaat tgaaggtcat gattgacgct
    53341 gagatagcgc ctttcaggaa aaagatgaaa gaagtcgaga atcaggtcaa aggaacatct
    53401 gaccaagtga aaaatgccac tgccaaagtt cgtgaacagt cgaactcaat cggtagtgcg
    53461 tttggtaagc tggctaagtt tgctggtttt gcaatccttg gtaagaaatt acttgatgtt
    53521 ggaatgtatt caacgcagac agctcttgaa gtgtcagcgt ctatgaacca aatcaagcga
    53581 cagatgggcg agagttcgca atctttcttg aaatgggtta acgataacgc caacgctatg
    53641 aatatgggag tgggtgaggc gaccaactac ggtgcagtct attcaaactt attttctgga
    53701 tttatcaaag ataccaacaa gctaagcgcc tatactgcta agatgttgca gacatcggca
    53761 gtggttgctg aaggttcagg gcgcacgatt acagacgtta tggagcggat tcgctcaggt
    53821 ctactaggga acaccgaagc aattgaggac ctaggaatca acgtcaatgt ggctatgatt
    53881 aagtccactg aagcttttaa gaagttcgca aacggacaaa gctggcaaca attagactac
    53941 caaacccagc aacaaatccg ccttatggct attctggaac aggctacagc caagtatggg
    54001 aataccttgt ctaattctgt aaatggtcgt atcagcctat ttaagtcgct gatgaaggac
    54061 gcagcattga accttggtaa ctctatgtta ccgattatca atgccattat gcctgtcttg
    54121 aactcttttg ctatggtttt gaagaacgtt actgctaaac tcgctgagtt tattgctttg
    54181 atgttcaaca agaaagcaac agtgaaagat ggtgttggtg gagcagttgg agacatgggt
    54241 aacgccatga aggatgctgc aggcggagca ggagaccttg ctgacgcagt agacgacgct
    54301 ggagattcag caggaggact tgctgacaat cttggagact cagccaaaaa cgctaagaaa
    54361 gctgctaaag agttgctagg tcttttggga tttgatgaga ttaacatctt gcaaaaacca
    54421 aaagatgacg acgcaggcgg ttctggaggc ggtggcaaag gtggtaaagg aaagggaggc
    54481 ggtggcggac ctttcaaaga catcttgcca gaagtcgagt tgactgacat ggacaacaaa
    54541 ttcaagagca tttttgatgg tcttggagat aagctcaaag ggttgtttga cctcttcaag
    54601 aaaggttttg atgcagcatt tagaccagaa ggtataaaac gcattaagac tgccttagac
    54661 caaatagcta agacaatggg agaaatcgcc actgacccaa gggttgtgaa tgcctttaac
    54721 cgaatggctg agaaaattgc ttatgcttta gggcaagtga caggctcaat agctactatc
    54781 gggctaggta tcggtgtttt ccttgccgaa agtattgcaa atggccttgg aaggcaaaaa
    54841 gaacgcatta ccagggcgct agtcgctttg tttgataatg ttggtaacct ttccgaggca
    54901 gtaggaaaca tagctcagga cttttctagt gctttctacg acgtcattac ctcaactggt
    54961 gcggttcgta tcggtagcgc tattgtgtca actctgttga gtttgacatc taccattgtt
    55021 gaagttggta gtaaattagc aggaagtttg tttaaaggtt ttgaaaaagt cgttgtgaca
    55081 agcgctccta aaatttcatc agtcttccaa agtttattag atactgttgc gcctgtattt
    55141 gagagcattg aaaggtctgt taacaaattt ggcgatggct taagtcgtgt ttatgatgaa
    55201 catgtagtcc ctgctattaa ctctattgct aatgctttta atgggctaat tgacattatt
    55261 cagattctct gggagaattc ctggcaacct tttgctgagt ttttatcagg agtattcggt
    55321 gttagtattg aaggaatttc agatttatta ggaggtggcc ttttagccac tttgggacta
    55381 ttggcgtatg ctattaagtt agtggcagat ggtttcaccg ttttttctga ctggtgtaaa
    55441 gaaaacaaag aacctatcgt agctttgata acaacttggc aaacgattaa tttcttatca
    55501 tgggcagaac aagctggagg acttgcagga gcattcagct tgttaggtag taaggtctct
    55561 ttgattgttg gaggaattaa gaatctaggt cttgctatta aagcattgac atttgataag
    55621 ttggtcagtt ttgctgaaac aatctatttg aacaccttat atgcaaaaga ttttgtggtc
    55681 aattcaggta aaacaattgc acagctagga aaaactgctt tagaacttgg taaatcagct
    55741 ctagcatgga ctgctcatgc agcgaaaatg ggattagcaa ccgcggcgga atttgcacat
    55801 tctgttgcag caggagtcgc tacagctgca acatgggctt ttaatgcagc gttagcagtt
    55861 ttgacaagtc caataacatg gattattgca gcaatcgcag ccttaattgc tatcggtgtt
    55921 ttgctctacc aaaattggga cactgttgtt gagtttgcta aaactgcatg gcaaggacta
    55981 tgtgatttta tcagtggtat ttgtcaagcg attggcgaat ttttcagcgg tctatggacg
    56041 aaactacaag aaatctttga gccgataggt caatggtttg gcgagaaatt ccagcaagca
    56101 tgggacgcta ttggaaatat atttggcaac ttaggctctt ggtttggtgg ccgttggaat
    56161 gattctaaaa acgcacttgc cgaagcaaat acttggcttg gtgataagtt caagtcaggt
    56221 cgggataaag tgaactcagc ttttgaaaaa gttggctctt ggttcggtga ccgttggaat
    56281 gatatcaaag atggagtgaa agaagctgat acatggtttg gagagaaatt tgagagtgca
    56341 aaaaagaaaa ctcagaatcc tttccaaaaa atcggttctt ggtttggtga tagatggaaa
    56401 gatatgcaag atgccttgaa agaaatcccc aactggttca agaatctgtt taatgatgca
    56461 atggataatg ctaaaaacat cgttaaaagt ggtatcgata aactaaaaag cttctttaac
    56521 tttgattgga gcttaccaaa aatcaaactc cctcacttta atatatctgg tagcttcagc
    56581 ttgatgcctc ctagaattcc atcattctct gtagattggt atgcacgagg cggtgtattc
    56641 aactctccta gcatcattgg ggtcggagaa gctggtcaag aagcggtaat gcctcttgaa
    56701 cggaatacag gatggatttc tatcttggct caaaaactgg ctgaaagaat gcctgctaat
    56761 aatgtaccta caggttattc attaccggct ggcgacatcg ttatccaaat cgcaggccat
    56821 gagttcggac gggtagctat ccaagaaatc aacaaggaac atgaacgagc aggtcaaacc
    56881 ttgctcaaga tttaggaggt taaatggcac aattgacaat caatggggtg gctgtgaagc
    56941 ctcccaaatc ttttcaagtc ggtattcaag atatcgatgg agagacaggg cgtaatgcca
    57001 atggcgacat ggtgcgtgac cgtatcacga ccaaacgcaa actagactgt gaatggggta
    57061 tgatgactca gggagaaata agtcagcttt tacatgctgt atcatctgaa ttttttgagg
    57121 tatcttatcc agaccccatg gatggccaag tcacaaagac tttctatgtc ggtgctagga
    57181 cagctcctag ctataccttt actgagaagt ttaaaccttg gtctggcgct aaatttaatc
    57241 tggtagagag gtaagaaaat ggacgcttta actagacgac aatttgacag atctatgttt
    57301 gccaaggaaa ggacgctggc tattcgtgtt ggtgaatatg cttcacggga tatcaaagag
    57361 gctagttttg agtatggcta catcaagggc gatacttata agcctggtgg aacctgcgct
    57421 ggtagcggta aaattacctt taccagtatc attaccacgt tcaataagct ggataccctg
    57481 caccctgaga ttggtctact ggttggggat acctaccagt gggtcaagat gggggaatac
    57541 ttcatcaacg atattgagat tgaccgaaac cgaaacacta ccacgcttga acttatggac
    57601 ggtatgttta agctcaatcg tgagtacgtg acggacttgc atttcccagc tgaagtacga
    57661 gaggttattc aggaaatctg cctgaaaaca ggcattgagt tagcgaatga ctatttcgga
    57721 atcagcgcga tgcgttatca tattgagcaa gttcctgagg gcaagaaact ttcctttagg
    57781 gatatgctga gcgctatgac tcagatgatt gggatgtctt gtttcttcaa cagagaaggc
    57841 aagatggaaa tccgtgattt gactgagtcc aatatcacga tcaacgctga cagttacttc
    57901 ttgcatggct tgaccaagag tgagattgag tatcagatag ctggtatcac ttgtaagacg
    57961 gacaagaagt ctctgacggt cggtatgaag acgggccggt ctttggaact ggacaatgtc
    58021 ttcatgaccc agagcgcttt aaatgacctg tattacaaac tgaaaaacct aacttactat
    58081 ccgtataatc tcaactacca agggcattta ctgcttgagg tcgggcagtg ggtaaccatt
    58141 cagaccaata agaaagagac ctttaaagtt cctgtgttaa gtcagagctt tacttttaaa
    58201 ggtggtctga gagggcgtat cagcgcagat agtaaggctg gaaacgatac tcagtattct
    58261 tacgagggta cgattaccaa gcatattaag caacaaggtg gcattgaagc gaaaatccaa
    58321 gcgcagattg aagcaacaga taaagatttt gaccaaaagg tcgacaaaat caaaaaagac
    58381 tttaacgatc aagtagaact tgccaaggcc aaggcggaag aagtcaagag agaactgtct
    58441 gacactatca atcagcgatt taatagcttt gacaacgggc cattgaaaga aactaagcgc
    58501 aaggctgagg aagctttgcg aaatgctggc gcaagtaccc tgcttgcaca ggaagctaag
    58561 cggattggac tggattctgt cgctagactt gaagcgttta agtcgcagac tacgagcgca
    58621 caaacggctc tgtcgggtga cttggacgct ctgaaacgga ctatcgcgaa tgat
//
LOCUS       DBEJZV010000009        57103 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.09, whole genome shotgun sequence.
ACCESSION   DBEJZV010000009 DBEJZV010000000
VERSION     DBEJZV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 57103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57103
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.09"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(17..496)
                     /locus_tag="ACL3S0_000706"
     CDS             complement(17..496)
                     /locus_tag="ACL3S0_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGR1311660.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            complement(618..2576)
                     /gene="ftsH"
                     /locus_tag="ACL3S0_000707"
     CDS             complement(618..2576)
                     /gene="ftsH"
                     /locus_tag="ACL3S0_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGR1311661.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMSGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2592..3134)
                     /gene="hpt"
                     /locus_tag="ACL3S0_000708"
     CDS             complement(2592..3134)
                     /gene="hpt"
                     /locus_tag="ACL3S0_000708"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGR1311662.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(3138..4415)
                     /gene="tilS"
                     /locus_tag="ACL3S0_000709"
     CDS             complement(3138..4415)
                     /gene="tilS"
                     /locus_tag="ACL3S0_000709"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGR1311663.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(4412..5680)
                     /locus_tag="ACL3S0_000710"
     CDS             complement(4412..5680)
                     /locus_tag="ACL3S0_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGR1311664.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5673..5795)
                     /locus_tag="ACL3S0_000711"
     CDS             complement(5673..5795)
                     /locus_tag="ACL3S0_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGR1311665.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            complement(5800..6168)
                     /locus_tag="ACL3S0_000712"
     CDS             complement(5800..6168)
                     /locus_tag="ACL3S0_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGR1311666.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(6161..6427)
                     /locus_tag="ACL3S0_000713"
     CDS             complement(6161..6427)
                     /locus_tag="ACL3S0_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGR1311667.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6495..10019)
                     /gene="mfd"
                     /locus_tag="ACL3S0_000714"
     CDS             complement(6495..10019)
                     /gene="mfd"
                     /locus_tag="ACL3S0_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGR1311668.1"
                     /translation="MVTLLDLLSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKRKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNK
                     KDYEILEGLLIFGESLLEIKEFKEENSI"
     gene            complement(10020..10589)
                     /gene="pth"
                     /locus_tag="ACL3S0_000715"
     CDS             complement(10020..10589)
                     /gene="pth"
                     /locus_tag="ACL3S0_000715"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGR1311669.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10660..11775)
                     /gene="ychF"
                     /locus_tag="ACL3S0_000716"
     CDS             complement(10660..11775)
                     /gene="ychF"
                     /locus_tag="ACL3S0_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGR1311670.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11895..13061)
                     /locus_tag="ACL3S0_000717"
     CDS             complement(11895..13061)
                     /locus_tag="ACL3S0_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR1311671.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIDFEKGGATVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLL
                     PAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIP
                     FNPARDVIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATG
                     LRIRECLALKWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKTVLMLRLY
                     KARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHA
                     SILLNAGLPYKEIQIRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKLKSS"
     gene            complement(13157..13609)
                     /locus_tag="ACL3S0_000718"
     CDS             complement(13157..13609)
                     /locus_tag="ACL3S0_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGR1311672.1"
                     /translation="MDKINYFSAEEAILLHDIEVIEKIGGLHGVKDKGRVFSVFEHLQ
                     NDDYYPDFETKLTVLVFNTVQFHMFNDGNKRSSIVFGIKFLTINHLDYLIPFFIETME
                     NIVLWVAMGLIDFNFLKEIISSILYYEELTEKVKEKLVQIALAEENNK"
     gene            complement(13609..14613)
                     /locus_tag="ACL3S0_000719"
     CDS             complement(13609..14613)
                     /locus_tag="ACL3S0_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGR1311673.1"
                     /translation="MTDLTTSQIERQNILNNSLALQKAEEILKVPGFYFEDTFYFTNS
                     QLATFFEVDIRTIERLVEAHKTELTENGYHTLRGEKLAKFKENAFATDTNVGSKVTQL
                     SISSFRTLLNFAMLLTNSDIAKQVRNTLLDIVINVLTEKTGGHVKFINQRDKNYLSTA
                     LEEDNARKIFTNAIDKYVSGSNFKYGQLTNEIYKAIFKERASEYKKILKLNKNDNARA
                     TMYSEVLIVIASFEKGVAYEIEQKSKSSNQKLTNTDVIEIIQRLANHPMQEPHLMHAR
                     EKMASRDLSFRNAKHEKLAEYIRPISEEDFERFIGEQSKSLSEQIDEHRQVFERLRDK
                     "
     gene            complement(14762..15718)
                     /locus_tag="ACL3S0_000720"
     CDS             complement(14762..15718)
                     /locus_tag="ACL3S0_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1311674.1"
                     /translation="MAKNSPQDLENREYFSKRLNLLMEQKGVRQIDLHNALDIPKSTI
                     TGYVKGKSLPTAGNLQKIADFLNVKKSFLDLRFIDTVSTSTLKELLDNNQREKVFEMF
                     FNKIKEILSFKKDYMNMEYIRGKIAFDQGVLGRVLQSSIINPGIVEIFNGLDLSDISK
                     NNEALLLSKQREAREYAYNNVLTMITNEYITRLINVIEREQALNTSYVHSEISNLINS
                     LNNKIDSYGAVVFEVNEIIEKIGIQDRKILGYCLQRKISSVQNEINDLVHNNTNNSFC
                     VTKNKIFTEKSDIIDTIEFDYYKGIQNRLNDLAEEIREHFSD"
     gene            15875..16108
                     /locus_tag="ACL3S0_000721"
     CDS             15875..16108
                     /locus_tag="ACL3S0_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1311675.1"
                     /translation="MEQWTLKACRVNAGYTLRQVAKKVNKNFQTVSKYEKDSTYIPFE
                     LLKELSAIYQVKLDNIFLGDSTKKIELNKRELQ"
     gene            16198..16824
                     /locus_tag="ACL3S0_000722"
     CDS             16198..16824
                     /locus_tag="ACL3S0_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HGR1311676.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIKTWEAKPKHAHSTMNNLLLKAVTDMNAKQLVKSRGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSV"
     gene            17276..17728
                     /locus_tag="ACL3S0_000723"
     CDS             17276..17728
                     /locus_tag="ACL3S0_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311677.1"
                     /translation="MTETTYENLTRRINRISAEMQEIGEKNGLSRLSLLASQTKFIKE
                     ELSRLLWIELPELNDSHKIEAVSKSTTGMFFHPGIFEMDAMRQAFFKRQAMHFFENEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            17725..17925
                     /locus_tag="ACL3S0_000724"
     CDS             17725..17925
                     /locus_tag="ACL3S0_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311678.1"
                     /translation="MTLDLDNMTQAEFDKQMAEIKERNPNIFQLISDFLDRKVTPEEV
                     DEFLKMERAEQVEYIKNYQARV"
     gene            17927..18142
                     /locus_tag="ACL3S0_000725"
     CDS             17927..18142
                     /locus_tag="ACL3S0_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311679.1"
                     /translation="MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPDYGRYIQLAGVNVWGGME"
     gene            18139..18432
                     /locus_tag="ACL3S0_000726"
     CDS             18139..18432
                     /locus_tag="ACL3S0_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311680.1"
                     /translation="MSYTMNLYPDIEKIPDETYFTKEIFLATCLNNTIRIAVARGVLT
                     SQLLDKETKEVVCKTLDTIIENQKAILQGVASGQITFVNKSKGEEGLDESIRE"
     gene            18413..18754
                     /locus_tag="ACL3S0_000727"
     CDS             18413..18754
                     /locus_tag="ACL3S0_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGR1311681.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            18747..19022
                     /locus_tag="ACL3S0_000728"
     CDS             18747..19022
                     /locus_tag="ACL3S0_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311682.1"
                     /translation="MFSLSRESEQDLAHGILEVVERYLEAREKVPPRLTKLINRVELK
                     EELKISDNTLNKWESQGLRRYQPPDDGARIIFYLVDDIRRFMGVENG"
     gene            19162..20022
                     /locus_tag="ACL3S0_000729"
     CDS             19162..20022
                     /locus_tag="ACL3S0_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HGR1311683.1"
                     /translation="MTIYEARGFQSNLVYPFDKMEPFQYIERFKPLVVPESADPEEYK
                     RTQAPYCLSGKVMPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSALFGY
                     SYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDTLF
                     NGFGDEGGRNVAVTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSS
                     IARAEYRKRG"
     gene            20066..21544
                     /locus_tag="ACL3S0_000730"
     CDS             20066..21544
                     /locus_tag="ACL3S0_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage/plasmid primase, P4 family"
                     /protein_id="HGR1311684.1"
                     /translation="MEVMEQEHPPRTMKELENRIFKAGEEWRAEHTETKVNETTGDVT
                     EKVAMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKT
                     FDVRIKPREWPQIKLMVRTLAKIRKPLESANLVPVKNGIIDLRTKELLPFSPKYVITS
                     KISTAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAI
                     FYGDGNNGKGTFQRFLINLIGESNISALKPAQFGEKHNLETLVGKVCNIGDEAPNEYL
                     KNPSDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVP
                     FNADFNGEKEKPWIKNEFLANKEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDN
                     DYLLSWVKHEYMEKGWHELDVVPVFIVTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQ
                     LTPNRYSLRKKRVPSEDFEKLEAWDVDKIKMRTPQHSITKQE"
     gene            21885..22052
                     /locus_tag="ACL3S0_000731"
     CDS             21885..22052
                     /locus_tag="ACL3S0_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311685.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEINDFMATVEVLDVKFSGTPSSESF
                     NSVAIVLVLYR"
     gene            22135..22665
                     /locus_tag="ACL3S0_000732"
                     /pseudo
     CDS             22135..22665
                     /locus_tag="ACL3S0_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22736..22993
                     /locus_tag="ACL3S0_000733"
     CDS             22736..22993
                     /locus_tag="ACL3S0_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311686.1"
                     /translation="MKRLAIETITKPMKLRGISKGIAELDGQRLEIDLDNLMIDFGGE
                     SFELDRIAGTKGGNRYFFALIVGDGAGCFINGIYILVAVLV"
     gene            23922..24332
                     /locus_tag="ACL3S0_000734"
     CDS             23922..24332
                     /locus_tag="ACL3S0_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HGR1311687.1"
                     /translation="MTPEQVKEKLEGVKWINKEIEGLYLELAALESGIIKKQELSNTR
                     VQTSRVNTTENNPISVLKLKEDTLQRIERLNEERMEISRLIDKLANPLERSVLRLFYL
                     NVLDAWQVAEEIDKSKTAVYIIRQKAIEHLANVG"
     gene            24488..24880
                     /locus_tag="ACL3S0_000735"
     CDS             24488..24880
                     /locus_tag="ACL3S0_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGR1311688.1"
                     /translation="MELDKFKTMMNVRERMTYFLRFQRMAGSENQVTIDEEAWKLVLP
                     YRWDLSGEHEKAIREGLEIFAQDINSIENKRARKYFIIHYCYMRKKTMSECVEMAATS
                     STSYHRYKQIAVLNFARIHQNGELEVYK"
     gene            24934..25092
                     /locus_tag="ACL3S0_000736"
     CDS             24934..25092
                     /locus_tag="ACL3S0_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311689.1"
                     /translation="MIEDFLIDLENIQLEDMEIDFNMDIDIDLNIDFEIDVDLDDLDL
                     TLLQELEA"
     gene            complement(25521..25715)
                     /locus_tag="ACL3S0_000737"
     CDS             complement(25521..25715)
                     /locus_tag="ACL3S0_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGR1311690.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANCWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(25780..26916)
                     /gene="dnaN"
                     /locus_tag="ACL3S0_000738"
     CDS             complement(25780..26916)
                     /gene="dnaN"
                     /locus_tag="ACL3S0_000738"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGR1311691.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(27075..28436)
                     /gene="dnaA"
                     /locus_tag="ACL3S0_000739"
     CDS             complement(27075..28436)
                     /gene="dnaA"
                     /locus_tag="ACL3S0_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGR1311692.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(28649..29407)
                     /locus_tag="ACL3S0_000740"
     CDS             complement(28649..29407)
                     /locus_tag="ACL3S0_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGR1311693.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(29465..30646)
                     /locus_tag="ACL3S0_000741"
     CDS             complement(29465..30646)
                     /locus_tag="ACL3S0_000741"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGR1311694.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            30829..31308
                     /gene="rlmH"
                     /locus_tag="ACL3S0_000742"
     CDS             30829..31308
                     /gene="rlmH"
                     /locus_tag="ACL3S0_000742"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGR1311695.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            31352..31425
                     /locus_tag="ACL3S0_000743"
     tRNA            31352..31425
                     /locus_tag="ACL3S0_000743"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31386..31388,aa:Arg,seq:tct)
     gene            31590..31715
                     /gene="comC"
                     /locus_tag="ACL3S0_000744"
     CDS             31590..31715
                     /gene="comC"
                     /locus_tag="ACL3S0_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGR1311696.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            31736..33061
                     /gene="comD"
                     /locus_tag="ACL3S0_000745"
     CDS             31736..33061
                     /gene="comD"
                     /locus_tag="ACL3S0_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGR1311697.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            33058..33810
                     /gene="comE"
                     /locus_tag="ACL3S0_000746"
     CDS             33058..33810
                     /gene="comE"
                     /locus_tag="ACL3S0_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGR1311698.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            33862..33933
                     /locus_tag="ACL3S0_000747"
     tRNA            33862..33933
                     /locus_tag="ACL3S0_000747"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33895..33897,aa:Glu,seq:ttc)
     gene            33939..34012
                     /locus_tag="ACL3S0_000748"
     tRNA            33939..34012
                     /locus_tag="ACL3S0_000748"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33973..33975,aa:Asn,seq:gtt)
     gene            complement(34053..34595)
                     /locus_tag="ACL3S0_000749"
     CDS             complement(34053..34595)
                     /locus_tag="ACL3S0_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR1311699.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            34774..36377
                     /locus_tag="ACL3S0_000750"
                     /pseudo
     CDS             34774..36377
                     /locus_tag="ACL3S0_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(36407..38959)
                     /locus_tag="ACL3S0_000751"
     CDS             complement(36407..38959)
                     /locus_tag="ACL3S0_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGR1311700.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMGFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIRFHVKLIYIIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(39021..40643)
                     /locus_tag="ACL3S0_000752"
     CDS             complement(39021..40643)
                     /locus_tag="ACL3S0_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1311701.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            40849..41874
                     /gene="trpS"
                     /locus_tag="ACL3S0_000753"
     CDS             40849..41874
                     /gene="trpS"
                     /locus_tag="ACL3S0_000753"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGR1311702.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFTKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            42026..43504
                     /gene="guaB"
                     /locus_tag="ACL3S0_000754"
     CDS             42026..43504
                     /gene="guaB"
                     /locus_tag="ACL3S0_000754"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGR1311703.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(43555..44652)
                     /gene="recF"
                     /locus_tag="ACL3S0_000755"
     CDS             complement(43555..44652)
                     /gene="recF"
                     /locus_tag="ACL3S0_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGR1311704.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNRN"
     gene            complement(44655..45023)
                     /locus_tag="ACL3S0_000756"
     CDS             complement(44655..45023)
                     /locus_tag="ACL3S0_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGR1311705.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SCRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            45182..46432
                     /locus_tag="ACL3S0_000757"
     CDS             45182..46432
                     /locus_tag="ACL3S0_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR1311706.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSEFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGISSADFKGWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            46429..47712
                     /locus_tag="ACL3S0_000758"
     CDS             46429..47712
                     /locus_tag="ACL3S0_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR1311707.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            47754..48575
                     /gene="rodZ"
                     /locus_tag="ACL3S0_000759"
     CDS             47754..48575
                     /gene="rodZ"
                     /locus_tag="ACL3S0_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGR1311708.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            48586..49131
                     /gene="pgsA"
                     /locus_tag="ACL3S0_000760"
     CDS             48586..49131
                     /gene="pgsA"
                     /locus_tag="ACL3S0_000760"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGR1311709.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            49128..49955
                     /locus_tag="ACL3S0_000761"
     CDS             49128..49955
                     /locus_tag="ACL3S0_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGR1311710.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPGELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            49940..50779
                     /locus_tag="ACL3S0_000762"
     CDS             49940..50779
                     /locus_tag="ACL3S0_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGR1311711.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            50772..51566
                     /locus_tag="ACL3S0_000763"
     CDS             50772..51566
                     /locus_tag="ACL3S0_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR1311712.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            51625..52443
                     /gene="mreC"
                     /locus_tag="ACL3S0_000764"
     CDS             51625..52443
                     /gene="mreC"
                     /locus_tag="ACL3S0_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGR1311713.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            52443..52937
                     /gene="mreD"
                     /locus_tag="ACL3S0_000765"
     CDS             52443..52937
                     /gene="mreD"
                     /locus_tag="ACL3S0_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGR1311714.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            53031..54209
                     /gene="pcsB"
                     /locus_tag="ACL3S0_000766"
     CDS             53031..54209
                     /gene="pcsB"
                     /locus_tag="ACL3S0_000766"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGR1311715.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            54433..55212
                     /gene="rpsB"
                     /locus_tag="ACL3S0_000767"
     CDS             54433..55212
                     /gene="rpsB"
                     /locus_tag="ACL3S0_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGR1311716.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            55291..56331
                     /gene="tsf"
                     /locus_tag="ACL3S0_000768"
     CDS             55291..56331
                     /gene="tsf"
                     /locus_tag="ACL3S0_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGR1311717.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            56686..56901
                     /gene="tnpB"
                     /locus_tag="ACL3S0_000769"
     CDS             56686..56901
                     /gene="tnpB"
                     /locus_tag="ACL3S0_000769"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR1311718.1"
                     /translation="MDSFSGQVFLFCGERKDRFKALYWDGQGFWLLYKRFENGKLTWL
                     STEKDVKALAPEQVDWLMKGFSITPQI"
BASE COUNT        18127 a         9855 c        10800 g        18321 t
ORIGIN      
        1 ttttttgcat gacttactag tgggtacgga tagtaaactc cttaaacaca atgcgtaagt
       61 ctcttaatac tctttgacgc cctcgaaatc gttcattgct taagacgcgt tctagttctt
      121 cttgcttctc tttactttgt ttgtttctat aatctcttag tgtttcatga aagagataat
      181 aatcatctag ccagagacct ccctcactta tacgatgact gagctcaccc acttcttcat
      241 agggttcttt atcgtatcta cgcttctgac tttcctgctt acggatatag tctaaaattc
      301 gatttcgaaa cttggttttg aaatatttcc ttaaacgtgg aatatcgtct accagtcctt
      361 cttctctact aatcaattca tgtaagcaga gcatgccttc ttggtcccaa tccgacaatt
      421 cccataaatg aaggtaatat tcatttctac acttatacac agtcccttgg acttcttcat
      481 acaattcttt aatcataatt ttcccctttc tagatacagt ctaacagatt agaaaacaca
      541 tttgttccat tttctccatt ctgttccctt tagctcctaa actgcacaaa aaagagaggc
      601 tccagcctct ctcagggtta tttttcgtca ttcatttttg actttacttc atcataggat
      661 agtgcatgag attcctcttc tactgcttca ggcatctttc ctgtttcgta aagagcttta
      721 atttgtgtac tatccaatgt ttcgtatttc aataatgctt ctgcaattaa cttgtgagtt
      781 tcacgatttg actgaataat ttcagcagct ttatttcgtg cctcatttaa taatgaacga
      841 acctcttcat caatttcata agctgtttgt tctgaaattg atttttgagg actctgtgca
      901 ccagacatag catggtttcc ttcatattgt actgggccaa gtttttcact cataccgtac
      961 tctgtaacca ttgcacgcgc catttgtgtc gcttgttcaa agtcgtttga agctcctgta
     1021 gtttggacat taaagataat ttcttcagct acacgtccac ccattaagcc agccaattgc
     1081 tctttcatat cttctttaga tagaagcatt tgatcctctt taggaagtgc aatcatgtat
     1141 ccgcctgcac ggccgcgtgg tacaattgta accttatgga caacgcgagc attcgacaag
     1201 actagaccaa caatggtatg tcctgcctca tggtaagcaa ccaattctcg ttctttttgt
     1261 gaaactgtct tatctttctt agaaggtcca gcaataactc tatcttctgc ttcatcaata
     1321 tctgaagcat caattatcga tttattgcga cgagcagcaa ctaaagctgc ttcattcaag
     1381 acattctcta aatcagcacc aacaaagcct ggagtttgtt gagccactaa tttcaaatca
     1441 acatcttctg ctaaaggctt gttcttagcg tgaactttca agattgcttc acgaccttta
     1501 acatcaggac ggccaaccaa tacttttcta tcaaaacgtc ctggacgcaa aagggcagga
     1561 tcaagtacat ctgaacggtt tgtcgcagcg atgacgataa tcccttcatt tccctcaaaa
     1621 ccatccatct caatcaaaag ttggttcaag gtttgttcac gttcgtcatt acctccgccg
     1681 agaccgactc cacgttgacg tccaacagca tcaatttcat cgataaagat gatagctggt
     1741 gctgcttttt tggcatcctc aaaaagagag cgaacacgac tagctccaac tccgacaaac
     1801 atttctacaa agtcagaacc tgagatacta aagaatggaa cacctgcttc tccagcgact
     1861 gccttagcaa gcaaagtctt acctgtcccc ggaggtccct ccaaaagaac acctgctgga
     1921 atacgggctc caagttttgt gaatcgtttt ggatctttta agaactcaac aacttcaact
     1981 agttcttgtt tttcttcctc agctccagca acatctgaaa atcttacttt aatatcttct
     2041 ttatttgctg ctttagcctt actacgtcca aaactcattg gattacggcc attgcctcct
     2101 cccatatttc ccatcataga gaataggaag aagaatagaa ttccaaatgg cacaatggat
     2161 acgagtagat taatccatat accacttgaa ctttcatgct taacagttac ttctgcttta
     2221 tggtcagtag caagtttttg caattctgat acggtagtat ctgcaggaag aatagtgctg
     2281 gtaaatttct ctaccttagt aacagatggc gtgaaaaact gaatgcctgt tccttcttta
     2341 cttgttttag gatttttata gacaccagaa acttcgataa cactaccatt tggttggtaa
     2401 gttaattctt ttacattacc atcggtaatt tcttgtacca actcagtata gttgatttgc
     2461 tgacttcctc ctgagttatt cccagaatag aaatactgga atcctgtcac aaggaaaaag
     2521 ataaataata accatagaaa aggattttta attaaaccat tattttgttt tttcattaaa
     2581 gattattctt tctaatttga atacacttcc tctttcaata ctccaatata aggaagatta
     2641 cgataatttt ctttgtagtc taaaccataa cctactacaa actcatttgg gatagtaaag
     2701 caggtatagt ctgcctcaat ttctacaaca cgtccttctg gtttatccaa caaggttgca
     2761 attttaacag aagctgcttc tctttcttta aacatatctc gcaaattctt caaagtttga
     2821 cctgtatcaa tgatatcttc tacaaataga acatgtcttc ctttgatatc ttgagtcaca
     2881 tcttgtttaa tattgataac accactactt gctgttccac catggtagct agaaaccatc
     2941 atgaagtcca tttcaatatg tgtatcaata tgtttgacca attcagccat aaaaggaata
     3001 gatcctttta aaatcccaac taagattgga ttttttcctg catagtcttt agttaattga
     3061 gcacctagtt ttttagctgc ttctgtaatt tcatcgtgtg aaacgaggac ttttttaata
     3121 tcgttttcta acatttttta cctatctatt ttttctatat aaagtacagt gttcattata
     3181 tcatttttcg tttttttact caaattattg gtcgcaattc ccaaaattga gacaatttca
     3241 ccaaattgct caataataag agcagagttt ctcttttcca tagggatttt caaatcaata
     3301 aataaacgtc tgagtttttt tctatgccca ttttgaatca aaacatctcc tgtttttcga
     3361 tgacgaatgt gtatggatgt ttcacgtgaa acaggtattt gttgaattga ttcaccttct
     3421 aatggaagtc caaaggaaaa taaatatcct tgataagcta cctgattttg atagtgtaac
     3481 acaagttcat cttccttttc atcagcctgc ggactgattt tacaaatctg aaactgttgg
     3541 tactctttta tcaattcata gccattttta atcggatgac gatactggct tttagatttt
     3601 aaaatctgct gaacttcagc aaactgagct tttgtaagat tcaaatctgg aaaacgattc
     3661 agataagttt gaagtaaaac tctttgtgta gactcagagt aagaaaataa ctgctgtaaa
     3721 tcttccacat taatattgtt agataattca gctattgcca aatcataatc taaaatttca
     3781 ttgccaatgc ctaagattgc atccctaaat cgaggatttt ctttttccaa ttctggtaag
     3841 taagagtttc gaatacgatt tcgaaaataa tgattctcct gatttgatgt atcttcaaag
     3901 tgaaaaattg atggaaagtc ttttttctga aaatgcaaga agggacgaat gatttctatc
     3961 tctccgacta cttgcttctc cttaattcct gatagatagc gcaagcgagt tcctcgaatc
     4021 aagcgcatca aaatcgtttc cacctgatca tcagcatggt gggcagtgac taaagctgtc
     4081 gcacctgtct ttttcataac ctcttgaaaa aaatcataac gaaaatttcg tgcacgcgct
     4141 tctgaaaatt ctcctgaaaa attgctgata taaataggaa gctctgcttc agcagccaac
     4201 ttccttaatt ccttttcttc ccaatctgat tcaattctct gcttatgatt cacatgagcc
     4261 agaatcaatt caatctctaa ctctttttga taagtagaca ataccttaaa tagaaacata
     4321 gaatctaatc caccagaaag agctagaacc gccttagcat gctttttgaa atatcccttc
     4381 ttgagaaaat gatttaaaaa atctggttcc ctcattttag aacctcataa acatccttgg
     4441 ctatcttaga aatcgtatca taatcagaat tcttagtgaa aatagaaaga ataaatggag
     4501 aatctgcata gacaacaccc gtatcatgct taaattcatc cgcatctcca attttatgag
     4561 ctactttaac agaaacacct ttggcaattc gctgactatc aaaatctgtt ttagtcaaag
     4621 actctagcac aaatccattt tgattataaa tagcttccat aaacttcccg gccatcttag
     4681 aagaaatcaa tttttctttt ggatcccaat catctcccat aatggcagac atcttggatt
     4741 tgaatgtggc atcagattgg tttgaaatgt aatatcccaa tagattatga gctacattat
     4801 cagattcttt tgatactttc gtaattaaat cctttaaaga atattcttta ttatcttctt
     4861 ttttaggaag actaccactt ccctctggtt tataagaacc tggaaaatca ttgactgcag
     4921 atacgtattt tacagtcgta tctaactgat aaagaccctc atttattttt tcttgcgtat
     4981 aatagagata ggagagtttc aaaacgctgg ctgcatacat cttttcatct tgattgatac
     5041 cagcttcttt tccagtagtc agttgcttaa cataaataga gaaagaatct ttctgatatt
     5101 tttcagataa catttcttga actttactca tccgattatc ttcttcagaa gttgattctt
     5161 tagctaccca tccagcctga tcaatatgta gaaattctct tccttctaca aacatggtct
     5221 tgtcgattga tacttgcgaa taagctgata aggatgattt cacttctttt aaatcataag
     5281 gactattgta cagtttaaag tcagattcta accatacttt ttttattgtt ggagttacct
     5341 ctgattgatc atataaaaat cgtttgtccg cagctataaa ttgatgattt gatagcttaa
     5401 atactggaat tccttgttta tttaagcgcc actcggttat ttgaaaactt gttttgggag
     5461 tcaatttccc agattccact actaaatctt cattcgcata aacaggaacc tctccataaa
     5521 ccatgggaga acttaatttt tctctaaaat aaataccaaa gtcagattgt gaaaggtaat
     5581 aaatttcttt cgaagtatag acgacttctt tttctgtgct aacgactttt gaaatggtca
     5641 aaaaacttgg taacaacaaa ataattaaga atttacgcat tcttcctttc cttttcttct
     5701 tgtaaacgca ataattgatt tttatcagcc aattcttcca gcttttcatc tgacaaactc
     5761 aaaaattgct ctattacgtc taataaattt tccattttat cacctttgaa gcaagtcagg
     5821 aatcgtataa actttttccc tcgacttaga ataatagtac ttcgctcgtg tatatttagc
     5881 agcataatct tcatctttca acttggtagc aaatgctgtc tccttatcct tttcatcact
     5941 caaagtttga tactgagttt gcaagtctgc taattgctga cgtctttgga gtaattgctg
     6001 ataactctgc gctaaattaa aagttggcaa gataaataat agcataatca aaatcaatac
     6061 ccctcccata aaacgattcc gtttttgtcg ttctttcatc aggtagcgac gacgttggta
     6121 ttcattttga ataaaagaat tattcaattg tacaatattt ttagacattt tcttctaccc
     6181 gtgtttcact gataatttca tacattcctg ctgcatcttc tttttttgta ctatctttca
     6241 tctctagtac ttttacaagc agcaacttat tgccaaagcg aatttcaact tggtcattaa
     6301 ctttcaagtc cgttgaactt ttggccaaga ttccattaac cttgattcta cctttatctg
     6361 ctacttcctt tgcgactgta cgacgcttga taattcgcga tacttttaaa tatttatcta
     6421 atctcatcct tattacctca atttattatt gtaccatttt tatctatttt tatctatttt
     6481 atagaagaaa aatatcaaat ggaattttct tccttaaact cttttatctc taataaactt
     6541 tctccaaaaa tcagcagacc ttctaaaatt tcataatctt tcttattttg gacatcaaat
     6601 acaagctcca ttaatccctt attctcagcg atgcctgctt ttaagttcgt tacggataaa
     6661 gctttaaaat aatcttgagc taaaaacaat cgttgagtga ctttttcaaa ttgaattgta
     6721 attttattat cttttctttt attatctttt ctttccacac gttgaacaaa gaccttgtcc
     6781 aagtatgatt taaccaaacc aatctctaaa agataggcta ctacatctgg gtattctcca
     6841 aaacggtcta tcaactcctc ttgtaactct tcataattga cacggttgtc aatttgacga
     6901 attttcttgt aaatttcaat cttatgtcgt tgatcagaaa tataagtatc aggaagatag
     6961 gcatcaattt gcaaaatcaa ctcagcattc cctttggttc ttgtgttagc gttagcatta
     7021 ccgtttcgtt tagcaatagc ttcctctaat aactgcgaat acaattcaaa accaacagaa
     7081 tcaatgaaac cagactggga ttttcctaaa agatttcctg ctccacgaat cgaaagatct
     7141 cgcattgcaa tcttaaagcc agagcccaat tctgtaaatc ctttaatcgc ttctaatctc
     7201 ttttcagaga cttcactgat tgatttttct ggacgataca tgagataagc ataagcaata
     7261 cgattactac gaccgactct tcctcttaac tgatataagg ttgacaagcc catatggtcc
     7321 gcattttcaa taaataaagt attagcattt ggaatgtcca cccctgtctc aataatagta
     7381 gtcgtcacca agatatcgta ttgtccctca ataaagtcta atagagtatt ttccaactgg
     7441 acttcactca ttcgaccatg aacatatcca atcgaagcct ccggaatcaa ctcctgtaat
     7501 tctgaaacct tctgaacaat tgtgtcaact ttgttgtaaa gataataaac ttgacctcca
     7561 cgctccattt cacgcaagac agcatcacga atgacactat cattcttttc caaaacatag
     7621 gtctgaacag gatagcgatt agtcggcgga gtttcaataa cagataaatc tctgattccc
     7681 agcatagaca tatggagggt acgagggatt ggcgtagcgg tcaaggttag gacatccact
     7741 tgtttcttca gttctttcaa agtttcctta tgcttgacac caaatcgctg ttcctcatca
     7801 ataatcatca agcccaaatc agcaaacaca acatcttttg acaaaacacg atgtgttcca
     7861 atcaaaatat cgacttgacc gtttttcaat ttttcaagtg ttgcagtctg ctctttttta
     7921 cttctaaagc gactcaacac atcaatatta actgcaaaat tttggaatcg ttccttaaaa
     7981 ttcgtatagt gctgttgcgc taaaaccgtc gtcggaacta gaatgacaac ctgtttgtga
     8041 tcattgactg ctttaaaggc tgcacgcata gcaacttcag tctttccaaa accaacatcc
     8101 ccaactaaaa gtcgatccat tggctgagaa gcctgcatat ccctcttgat ttcctcaata
     8161 ctacgaagtt gatcatccgt ttcaacataa gggaaagcat catcaaaggc atcttgatca
     8221 tcatcatcag ctgagaaagc aaaacccttc aactgactac gttcagagta gagtttgatt
     8281 aaatcatcag ctatatcctc tacctggttc ttaacctttt gcttggcctt tttaaaatga
     8341 ccgtcattta atttattgag ttttggagct ttaccatcac ttgaaatata tttggacagt
     8401 agatgaatct gttccacggg gatagaaatt tgatcaccat tttggtattg gacactgaca
     8461 taatcgcgat gaattccctt gatttcaatg gtttcaattc ctagatattg accaatccca
     8521 tggatatgat ggacaacata gtcccctttt tcaagttcat tgtaatcttt taatctctct
     8581 gcatttgaaa catgttgtct tcgaaaacga cgctttaatt tcttttgaaa aatctcatgt
     8641 tcagttatca ataaaatctt ttcatctaca aaatgaaaac catgtctgag attaccctct
     8701 attaagttta cagattcttt acagatactt gtcttatctc tagaatccaa tttaatctga
     8761 tattcctcta acatatcctc caatgtttta cttcccattg aattgctaga ctgcagaata
     8821 atggtgtaat ccattttttt atatcgttca atttcttctt ttagaaaaga aaactgattg
     8881 aaaaattcct gcataggata ttgattgaat tgataaattt tgtcaaattt gagatttcct
     8941 aaaccctttt gaagattaga gaaaaaggtc actggacttt gttttttata gatttgttca
     9001 atatcagaaa aatactgcat atcagaaaat gctttactat tctgtaattc ttctgtaaag
     9061 tactgcgcta attctctttc aaagacttca tactgattca tcaatttttg ataatcatca
     9121 aagaatattg gagtatcttt ttcaatataa tcaaagacag tccatgtctt atcatagcac
     9181 aaagataaaa acttccgaga gtctgcatga ctttgttttt ggtgaaaact tgaaagaatt
     9241 tcttctaggt atgatttcaa aataggtgat aaagtttttg aaatttgttt ttctaaagct
     9301 gactgtcctc gttgataatc cttttctctc aaaagcatat cactagctgg aaagatagtg
     9361 agttctgtct tattttcttt cgataattgt gtttctactt caaatgacct gataccatca
     9421 atttcatcac caaaaaactc aattcgacaa ggttctaact gggatatttc aaaaatatct
     9481 aaaatatctc ctcgaagact aaattcgccc tgagtttgta cttgagtaac ttttcgatag
     9541 ccattttcct ttaactgatg gataaacgcg tgttgatcat attcttcacc aactgagatt
     9601 tttacaatac tatctttgaa tgcattggga gacggtaaaa tcaatcgact tgctgcgata
     9661 ttacaaacta aaatcccttt cttagatgaa tcagtcaaaa aacgcaaggc ttcaacccgt
     9721 gaaataattt tttcctgtga agacatcaaa aactccacca taggagcatc atctaccaaa
     9781 aatggataga cgagttcctc acccaagata gatataagat cactaacaag tccttctgct
     9841 tctccataag ttgacgtcaa taacacaatc ctatcttctt tttctaaact gcttgcaatt
     9901 gcaagagcct tagtagatgt tgataaacca agtattagtt gtcttttctt atctgttaaa
     9961 ttttgatgcc attttttaat ctgatcattt tctgagagta aatctaataa ggtcaccatt
    10021 tatccgttat acctctgcat tgttttctca aaatttttct cttgtaaata gtagtttaca
    10081 gaatcgtcaa ctttgtcaac agactgtaaa ataccgatat aatcatccct gtcaaactta
    10141 ctcaaaacat gatgaacaac tgacatacca tttttaggtc ttccaattcc aatcttaaca
    10201 cggttaaaga cctgagttcc tatatgttga ataatagact tgataccatt atgaccacct
    10261 gctgagcctt ttgctcttaa acgaattttc ccaacttcca tgtcaagatc atcgtaaatg
    10321 ataagtaaat cgtcaatatc caaaccatag taagttaata aagcatgaac tgcttttcca
    10381 ctttcattca taaaggtcgt tggtttaacc agataaattt tttctccatt taggaaaaag
    10441 gatgctaggt cagcttgaaa tatcttatcg tgtgtaaaag tgacattctg tttcttcgct
    10501 agttgatcaa tcaacataaa accaacattg tgttttgttt caaaatattt atcccctgga
    10561 tttcccaaac ctacaagtaa tttggtcatt tatttttcct ttcaaaagcc aaaagggttg
    10621 gaattttttt ccaacctaat tgacaccatt tattaatttt tagacattaa agcggaattc
    10681 catgatatcg ccatcttgaa cgatatattc ttttccttct tcacgcaagc gtccagcttc
    10741 ttttacggcc ttttcagatc cgtatttcac tagatcttca tatgacatgg ttactgcacg
    10801 aataaagcct ttttcaaagt ctgagtggat aataccagct gcttgaggag ccttcatacc
    10861 acgtttgaaa gtccaagcgc gaacttcttt ttcaccagct gtgaagtaag ttcccaatcc
    10921 aagcaagtgg taagctgcac gcgtcaactt atctacacct gattctgtca aaccaatggc
    10981 ttcaagaaac tcttttttat cttcatcatc caattcagaa atttcttcct cagcacgcgc
    11041 agaaataacg actacttcag cattttctgt cgctgcaaat tcacgaattt gtttgacata
    11101 gtcgatagag tcaggttctg aaaccacatc ctcgtccaca ttagctacat aaagaactgg
    11161 tttagtcgtc aaaaggaaaa gacctttgac aaccttttgt tcctcatctg taaattcaat
    11221 ggtacgagct gatttcccgt cttctaggac tggtttaatc ttttgaagaa cattgaattc
    11281 tgctactgat tctttatctt tttgcgtacg tgccatcttt tctacacgcg catatcgttt
    11341 gttcactgat tctaagtcag caagaattaa ttccagatta attgtatcaa tatctgcaag
    11401 tggatctaca aaggcgtctt cacgtccttg ctcgcgcatt acattttcat catcaaaagc
    11461 acgaactacg tgaacaatcg catctacttc acgaatattg gccaagaatt tattccctag
    11521 cccttctcct tttgaagctc cttttacaat ccctgcaata tctgtaaatt caaatgttgt
    11581 gggaactgtc tttttaggag ttatcatttc agttagtttt tgtaggcgtt catctggaac
    11641 ttccaccatt ccaacatttg gatcaatagt cgcaaatggg tagtttgctg cctctgctcc
    11701 tgcttttgta attgcattaa atagtgttga tttaccaacg tttggcaaac caacgatacc
    11761 tgctgtcaaa gccatatttc tcattctccg ttttcatttc aatccctaat attataacac
    11821 aaaaagggaa aacttgctaa aattccttga tatagctatt tcccataact gaaataataa
    11881 ttttatggac ttttttagga actttttaat ttttcaatag ctttttcata aaatgaagta
    11941 gcatttttct gattgtcttt ggataggtgg ctataaatat ccatggtcat agaaagtttt
    12001 gcatgaccga gccgtatttg tatctctttg taaggtagtc cagcattgag caagatacta
    12061 gcatgagtgt ggcggaaggc gtggaacgta aaacgagggc atccagcacg ttccaaatgt
    12121 tttactaacc tgaaactaag cattctagcg tctatatgct tatcaaagct attagagaat
    12181 actttctcat aggtcaaccc catttctttc cctatttggg attgtcttgc tttatagagc
    12241 cgtagcatga gcaccgtctt attatccaag tcaattaccc taatacttga tttagtctta
    12301 gggccagtga tttctttgat aatatttaac gttttattta cgtctagtgt gccgtttttt
    12361 aggtcaatat cagaccattt gagggctaaa cactcacgaa tacgcaaacc agtcgctaaa
    12421 agcgtcttat atagcaccgt atcgtagaaa tttttgtaag tgtttggcag ctgctccagg
    12481 taagtcaaga atttttttaa gttatcatca tccagatatt tcagtttttg cccttctttt
    12541 tccttacgac gtggcacgat aacatcacgg gcagggttaa aggggatagc ttgcaaagat
    12601 acggcatatt taagtatgcg tttgtttaga gagtgaagga gcggatattc ttggaatcct
    12661 ttgcctagtt gattatagtc ttttgcccat tgattgactt gcttttgaat gattgggggc
    12721 gtcagtttat ccagcctata atttccgaaa gctggaagta gatatttatc tattttgaat
    12781 ttggtaccca ttaaggtcga ttttttaacc gtatggcagt acgtttctag ccaattctcc
    12841 accagttcgg cgtaagtctt tatctccacc gctttatata ctgtagcccc tcctttttca
    12901 aagtcgattt gagcctgtag cgctttggct ttgagttctc tcttggttcg ccctgatata
    12961 gtcgtcttga ctttcttacc tgttacggta tcgataccaa ggtagacgct agagcgatag
    13021 actgtagacc cgtctttttt ggtgtattct gttattttca tgatgataaa cctttctaaa
    13081 atacatcagc aggcaagcta ttattaaaaa ggttttagat tatggtttat atcatgttga
    13141 gcttacggga aagattttat ttgttatttt cttcagctaa agctatctgt acaagttttt
    13201 cttttacttt ttcagtgagt tcctcatagt agagaattga agaaataatt tcttttaaaa
    13261 aattgaaatc gattaacccc attgctaccc ataagacaat attttccatt gtttcgataa
    13321 agaagggaat gaggtaatca aggtgattga ttgttaaaaa tttaataccg aagacaatgc
    13381 tacttctctt atttccatca ttgaacatat gaaattgaac tgtattaaat actagcactg
    13441 taagttttgt ttcaaagtct ggatagtaat cgtcattctg taagtgttca aatacactaa
    13501 atacccttcc cttatcttta acaccgtgta aaccacctat tttctcaatt acttcaatgt
    13561 cgtgtagtaa aattgcttct tcagcagaaa aataattgat tttatccatt atttatctct
    13621 caatctttca aaaacttggc ggtgttcatc aatttgttcc gaaagtgatt tactttgttc
    13681 gccaataaat ctttcaaaat cttcttcaga aattggacgg atatattctg ctaatttctc
    13741 atgtttggca ttcctgaaag atagatccct actagccatt ttctctctgg catgcattaa
    13801 atggggttct tgcattgggt gatttgctaa tctctgaatt atctcgatta catcagtatt
    13861 agttagtttt tgatttgaag acttactctt ttgttcaatc tcataagcaa cccctttctc
    13921 aaaactagca ataactataa gtacctcact atacattgtt gcgcgagcat tatcattttt
    13981 attcaatttc agtatttttt tatattctga tgctctttct ttaaagattg ctttgtaaat
    14041 ttcattcgtt aattgaccat atttaaaatt acttccagag acatacttat caatggcatt
    14101 tgtaaatatt tttctagcat tatcttcttc taatgcagtc gatagataat ttttgtcacg
    14161 ctggtttata aattttacat ggccaccagt cttctcagtt aacacattaa tgacaatatc
    14221 aagtagggta tttcttactt gcttagctat atcactattg gttaacaaca tagcaaaatt
    14281 aagcaatgtt ctgaacgatg agatacttaa ttgtgtaact ttgctaccga catttgtgtc
    14341 ggtagcaaaa gcattttctt taaatttagc tagtttttct ccacgtaaag tgtgataacc
    14401 attttcagta agctccgttt tatgagcttc aacaagtctt tcaatagttc gaatgtcgac
    14461 ttcgaaaaag gtagctagct gagaatttgt aaaataaaaa gtatcctcaa agtagaaacc
    14521 aggtactttt aaaatctctt cagctttttg taatgctaaa gaattattta aaatattttg
    14581 tctttctatt tgtgaggttg tcagatcagt cataatttct cctttttgtc gagttaattt
    14641 gccaataact cccgatattt caagagtttt attttatttt cgtgtcgtta gagtatatta
    14701 gaaaatcttg aactccgcga atacacgcgc ttcaggattg ttgaacattg tggcgcgtgg
    14761 gttagtcgct gaagtgttcc ctgatttctt cagctaaatc attcaagcgg ttctgaatac
    14821 ctttatagta atcaaattca atggtgtcaa tgatgtcact tttttcagta aatatcttgt
    14881 tttttgtaac acaaaagcta ttatttgtat tattgtgaac aaggtcattt atctcatttt
    14941 gaacagaaga tattttcctt tgtaagcaat agcctaagat ttttcgatct tgaataccta
    15001 ttttttcaat tatttcattc acttcaaaga caactgcccc atagctatca attttattgt
    15061 taaggctatt gataagatta gaaatttcag aatgcacata ggaggtattg agagcttgct
    15121 cacgttcaat aacgtttatt aaacgtgtaa tatattcgtt agtaatcatg gtgagtacat
    15181 tattataagc gtactcccta gcttcgcgct gtttggaaag tagtagagcc tcattatttt
    15241 ttgagatatc tgataaatca agtccgttga aaatttcaac aataccaggg tttattattg
    15301 aagactgaag aacgcgaccc aaaacaccct ggtcaaatgc tatttttcct cgaatgtact
    15361 ccatattcat ataatctttt ttaaagctaa gtatttcttt gattttattg aagaacatct
    15421 caaaaacctt ttctctttga ttattatcta gcaactcttt tagtgtgctg gttgaaactg
    15481 tatcaataaa ccgcagatct aggaaagatt tttttacgtt caaaaaatca gctatttttt
    15541 gtaaattccc agcggttggt aaagattttc cttttacata tcccgtaatt gtacttttag
    15601 gaatatctaa agcgttatga aggtcaattt gtctaacccc tttttgttcc ataagaaggt
    15661 tgagccgttt agagaagtat tctctatttt caagatcttg aggactattt ttagccatga
    15721 ctttaaccct ttcagttgta agttatacat tgattataac acaaaataaa aacaaagtac
    15781 gaaaataaat aaactttttt ctaaaaacac ttgactaagt acgaaaataa tagtactatt
    15841 aacttatcac ttttgaaagg aattgttaga ttatatggaa caatggacgt tgaaagcctg
    15901 tagagtaaac gctggttata ctttgcgaca ggttgctaaa aaggtaaata agaattttca
    15961 aactgtctcc aagtacgaaa aagatagtac atatataccg tttgaacttt taaaagaatt
    16021 gtctgcaatt taccaagtta aattggacaa tattttttta ggagatagta cgaaaaaaat
    16081 agaactaaat aaaagagagt tgcaataatg agagtattat tttaagtcaa tggtggcaga
    16141 aatcaaacca gacataacaa tagatgaatt attttatagc tagaaaggag caaaccaatg
    16201 gaactagtct atatggacgg taaaaaagag ccgtatacac tgagcagtat tgtggcagag
    16261 tgtgcagaag tcaagcacag acatttgaag attttgctaa ataaacaccg agaggacttc
    16321 gagagtttcg gaaaggtgca atttaaaatt tcaccttcag aaagtgggca aaatgtacgg
    16381 gactatattt taaatgaaca acaagcaaca ttgctgatca cttacttacg aaatacagaa
    16441 cccgtaaaag agtttaagaa gaacctagtc aaagcattct ttgaaatgcg tgaggaactt
    16501 tctaagtttc gtatgcagag ggcgctagaa aagccaaaaa gaaaaacctt gcatgacagt
    16561 attaaaacat gggaggcaaa acccaagcac gcgcatagca ccatgaacaa cctgttactg
    16621 aaggcagtaa ctgacatgaa cgctaagcag ttagtaaaaa gccgtggggg ctataatggc
    16681 attgatagct tgaccagtga cgagctggag caataccagg catttgagga tatggtaata
    16741 gccatgattg gcttgaatat gagttatcag gaaatcaaag ctatggcatt cagaaataaa
    16801 aaaacacgcc aaagaagcgt gtgagagcaa caaaaaaggc ttagcaataa ccacaccgca
    16861 gagcctttca cactaacact aaaacgaatt taacaaaaag caggcaagct attatcaaag
    16921 aggttttagt aaagatttat acctagatta tagcatattt agggcaattt gaccatacgg
    16981 agagcgccaa ctctttaaac tggtactttc tcacgctttc aatttggcga gtctgagcgt
    17041 gaggctagta cttacaagaa aaaactgtat aagaaacaac tcaaaaagcc ccacgctcag
    17101 aagtttggcg accgagagca tgaggctgta ggcaagaaaa actgtataag aaacaaccat
    17161 tcaaaatccc cacactcgcc atcgctcaac tttgagtgtg aggatcagca ggtatagtaa
    17221 aaggtattaa atggccctta gggcaactac acaacataga aacagaggta aaaacatgac
    17281 agaaacaaca tacgagaatt taactagacg tataaacaga attagcgcag aaatgcaaga
    17341 aattggcgaa aaaaatgggc ttagtagact ttcgttattg gcaagtcaga caaaattcat
    17401 caaagaagaa ttatcccgtt tactttggat tgaactccct gaattgaatg acagccataa
    17461 aatcgaagcg gtctctaaaa gcactacggg aatgtttttc caccctggta tttttgaaat
    17521 ggacgctatg cgacaagcat tctttaaacg ccaagctatg cacttttttg agaacgaagc
    17581 agagcaacag gcgtatatag aacatgctga aaaggagtat ttagaggcta ctataacctt
    17641 aaaagatatt ctttttaact ctaaaaatgg aactcagaga gtaaataaaa gttgtcttat
    17701 agagaagttt gaggaggcaa tgcaatgaca ctagacctag acaacatgac acaagcagaa
    17761 tttgataaac aaatggctga aatcaaggag agaaatccaa acatttttca actgatttct
    17821 gattttttag atagaaaggt aacacccgaa gaggtggatg agtttttgaa gatggagcga
    17881 gctgaacaag tggaatatat taagaattat caagcgaggg tataacatga atgagctaga
    17941 tataagtaac acacaggctg ctgtcttaat cgtgattttg attggcttac tgctttattt
    18001 aaaccaccga gaccgcaaaa aaagcgccca aattgagcga gaaaaccaac agacgataaa
    18061 aacacctagc gaggatttaa accctgatta tgggcgatat atccagcttg caggagtcaa
    18121 cgtatgggga gggatggaat gagttacaca atgaatttat accccgatat tgaaaaaata
    18181 ccagatgaaa cctattttac taaagagatt tttctagcaa cgtgcttgaa taacacaatc
    18241 agaatagcag tagccagagg agtgctaaca tctcaacttt tagacaaaga aactaaagaa
    18301 gttgtttgta aaaccttgga tacaatcata gaaaatcaaa aagctatttt gcaaggggta
    18361 gcgagcggac aaataacctt tgtaaataaa agcaaaggag aggaggggtt ggatgagtct
    18421 atcagagaat gacaagcgag ttttaagact aatcaaggta ggggctgaga actccataac
    18481 agggtcagaa attagcctga caaccaagct aacagaaaga actgtacgtg acattatcaa
    18541 gcgtctagta gttaagcaca acatccctat tgtaggggtt agatgtggcg tttttagtgg
    18601 gtactttatt ccagcgaata aaggcgagtt actagatggc gctaaggctt tttacaacca
    18661 agtacaggag gagagcaagc gcctagcggt gttgatgaat agcgacctag aaagctacaa
    18721 agaaaccttg aaggaggtgg gcggatatgt ttagcctaag ccgagaaagc gagcaagacc
    18781 tagcgcatgg cattctggag gtagtggaaa gatacctgga agcgcgtgag aaagtaccgc
    18841 caagattgac caagttaata aatagagttg aactcaaaga ggaattgaaa attagtgaca
    18901 acacgctgaa taagtgggaa agtcagggtt taagacgcta tcaaccgccg gacgatggtg
    18961 ctagaataat attttattta gtggatgaca ttcgtaggtt tatgggggtg gagaatgggt
    19021 agatataaca cacacccagc gcaaggcgga ggtcattatc atgacattaa attgtataag
    19081 caccgtggca gatctttgga acagttccaa gaacaaaagc tactgaagaa gttaaaaaaa
    19141 aacgcaaaaa ggggcgatag tatgacaatt tatgaggcta gaggtttcca gagtaatctt
    19201 gtctatccat ttgataagat ggagccgttc cagtacattg aacgctttaa gcctttggta
    19261 gtccctgaaa gtgctgatcc ggaggaatac aaaagaactc aggcgccata ttgtttaagt
    19321 ggtaaggtta tgccggagaa aaacgggagt tacaaacgaa acaactccag tctaatctat
    19381 cgggatttga ttttccttga ttatgacgat atacagggga cgactgagga cttcatagaa
    19441 gccgtttcta gcgctttgtt tggctactct tatatcttat acccgactat caaacatagc
    19501 atagaaaagc cccgttttcg ccttgtggtg aaatctaaca acgtgatgaa cgaggcaacc
    19561 tataagcagg tagtaaaaga gattgctgac aagattgggc taccctttga catggccagt
    19621 ttaacctggt cacaactcca agggctacca gtaacaacag gcgacccagc aacttatcaa
    19681 aagattgtag agcatggact tgattatcca gtccccaagg ttgaaccaag agcgaagcaa
    19741 ggaactactg agcgttataa acctagagta agtggccaga ggtcaatgac tatgaggatc
    19801 attgacacgc ttttcaacgg atttggagac gagggagggc gtaacgtggc agtgacacgc
    19861 tttgtgggat tactcttcaa taagtgggtt gattgtgacc tagagaccgc ctatgaactg
    19921 acaaagatag ccaatagtgt gacagttgaa ccattgccta ttgaagagct agaccgcact
    19981 tttagcagta tagcacgggc tgagtataga aagagaggtt agaaccatag aactagaaga
    20041 attagcaaac ctaaaaagtg aaatcatgga ggtaatggag caagaacacc ctcctagaac
    20101 gatgaaggag cttgaaaatc gtatctttaa agctggagaa gaatggcggg cagaacatac
    20161 tgaaactaag gtaaatgaga ccacagggga cgttaccgaa aaggttgcca tgcctcagac
    20221 attcacagta gcaaaaatac tgagcgagat tgtcacattt acttttatca gcaagagcaa
    20281 tatacctgat tatagcctgc tctatatcta tgatttagac gagggtatct ataccgctag
    20341 taatgatcta ttcaatcttt tgtgtaagac ctttgacgtt agaattaaac ccagagagtg
    20401 gccacagatt aagttaatgg ttagaacatt ggcaaagata cgaaaacctt tagagagtgc
    20461 taaccttgta cctgtaaaga atggcattat tgacctaaga actaaggagc tactcccctt
    20521 tagtcctaag tatgtaatta caagtaagat aagcacggcc taccacgcgc ctaaacgagt
    20581 cccaacagat agagagggca aaacttttga tgattggcta aactcaatcg cttgtaatga
    20641 tagtgaactg gtaacactgt tttggcagat tatccttgaa gctattaacc ctaaccatac
    20701 ccgaaataag tttgctatct tctacgggga cggtaacaat ggtaaaggga cattccagcg
    20761 cttccttatc aatctgatag gggaaagtaa tatatcagcc ttgaagcctg cacagttcgg
    20821 agaaaagcat aacttggaga ccttggtagg taaggtttgt aatattgggg atgaagcgcc
    20881 taacgaatat ttaaaaaatc cgtctgattt aatgagtatc actagtggcg acactgttct
    20941 agtcaatcca aaaggacgcc cagcctttga agctactttc aagctattca atatcttttc
    21001 agggaattat attcccaatg gtggcaacaa gacaaaaggc tggtatcgta gaattatgat
    21061 cgtccctttt aatgctgact ttaacgggga gaaggaaaaa ccttggatta aaaatgagtt
    21121 tttagcaaac aaggaagtcc tagagtatgc cctctacaaa gctatcaatc aagagccatt
    21181 tactcacttt atcgaaccta aagcagttaa aggactccta gaagaatacc aggaggataa
    21241 tgactactta ctttcatggg ttaagcatga atacatggaa aaaggttggc atgagctgga
    21301 cgtagtacct gtttttatcg ttacaagatc actaaagcac tatgccgaag atatgggaat
    21361 acccaaaccc aatgtttacg gggctggtaa agaaactatc aagcacttac aacagttgac
    21421 acctaatcgg tattctctaa gaaagaaaag agttccttca gaagattttg aaaaactaga
    21481 ggcatgggac gttgacaaga taaaaatgcg gacacctcaa cactctatca ctaaacaaga
    21541 ataagtgtga cgttcttttt ttgcttaaac ccttgataat actgattttc ttaaaaaaag
    21601 tgtgacgttc tcaaaaaaga aggttacacc ccttgaagcc ttgatatatc tagctttagg
    21661 ggaataggtg tgacgttgtg acattctttc caactcttat atatagagaa aaatgcagta
    21721 tttatatata ggaacgataa aacaaaagaa cgtcacaggg tcacaggggt ggtgaaacac
    21781 ctagagcctc aagggtttga acgtgtgacg ttctttgtca cagaaggtca cagaacacga
    21841 aaaatattac ataatttacc ttaaaataaa gaaatgacaa caacatgaaa gttaaactat
    21901 ttgaatatac tagacgatgg gaaaaagaag actttgagaa agagatcaat gacttcatgg
    21961 caactgttga agtgctggac gttaaatttt ctggtacacc atctagtgaa tcctttaatt
    22021 cggtggctat cgtattggta ttatacagat aacaaaatgg ggtagatagt accgaccccc
    22081 ttgtaatggt gtaactacta gtgacacctt taaaacagaa agaggaaaaa caacatgaca
    22141 ttaaaaacat tttcggataa agccaaaaca tttactttca cttacgaatt taaagaccta
    22201 gatactgcta tggtagcagg tcacgcgcta ctgggatata tgactgggac ttatgaagta
    22261 ccatctattt caataactca caaggataaa gggacgcttg tcgctgagta tgtggaagat
    22321 cacaagctaa acaagacttt caagcgtatt tgtgacagtt tcaaagacta ttacaaccaa
    22381 ccagtggacg atgaagcatt tgaagaacgt tataaacggg agcgcgtgct ccaactcaaa
    22441 gagtaagagg actttgagaa cttgctggaa aaagtaacag actacgagct ggaactatta
    22501 gactatgctg atcgcttgct ttctgataag cctatcccta tggactctat gaccgctttt
    22561 ggtacgttgg aaatgctggg cgatgaaagt attagcctac tccaaaagtt ggacgtagag
    22621 ggcgaatata aaggccttgc tggttataca gagcatttga agtagaacac aggggagcaa
    22681 tccccttttt gttatcaagt caatagtttt gggtttttcc atataggggg aaataatgaa
    22741 gcggttagca atagaaacaa tcactaaacc aatgaagctg agaggaatat ctaagggtat
    22801 agctgagttg gacggtcaac gtttagagat tgatttggat aatttaatga ttgattttgg
    22861 tggagagtca tttgaattag acagaatagc aggaactaag ggaggtaata gatatttctt
    22921 tgccctgatt gtgggagacg gtgcaggttg ctttataaac ggtatttata ttttagttgc
    22981 ggtacttgtc tagatatcca caagagcacc ctgaaccgta gtaaaacgga ttgccaatac
    23041 tactgggagc ttgcactaaa agaagccaga aaggtagaac cagggtggag tcctagacgt
    23101 ggtggatata tgtttgatag tttccctgaa agaccaaagt atatgaagcg tgacaggtat
    23161 cataagcact ataagaagtt tttgaagtat attgaaaaag gagatagatt ttggctgaat
    23221 ggtttgagat tgtaggacaa tatgaagtag tgtgcaattt acaaaacaaa caaatactac
    23281 atatttgacg gtttgaatgt taaaaaagct agatatatca aggatttaag taagtagagt
    23341 gttccaaaag agggtgaggt aagggtgagg ttacatataa aaagtacaag gttagtacaa
    23401 ggtcacatac ttcaaaatag caaggtttta gcaaggtaca gggctttttt ctagtgatag
    23461 aaccctaata ttaccctaag gtatagctac ttttttagaa ccatagaacg gtaaggttac
    23521 ggtaaggtat cgaagttttc caatggtgag gtaagggtga ggtaagagca aaaaatgtaa
    23581 aggttttgtc aaggttgcgt atttaaaagc cccaaggtta ccacaaggta gagaggttta
    23641 ccgagggtta gaaaaggtga gattttgctt aggtagtggc agtaaatatg cctggaaaat
    23701 ggcagggtta tgtgtgttga actccgagcg aacgccgaga aagtggctat atctccctcc
    23761 ccacgcactt ctatgagctt cacaccgtca ttgtacattt tttctcacgg ggaagcattt
    23821 gaagctagag cgaacataga gaaaacgaaa aaagccaaga cactctctgt ctcagctaat
    23881 agttctcaca aagactatta tatcatagag gaggccgagg catgacacca gagcaggtaa
    23941 aagaaaaact agagggcgtt aagtggataa acaaagagat agaaggctta tatttagagc
    24001 ttgcagcttt agaaagtggt attatcaaaa agcaagaact aagcaatacc agagtacaaa
    24061 caagcagggt aaatacgacc gagaataacc ctataagtgt tctaaaacta aaagaggata
    24121 cacttcagag aattgagcga cttaatgaag agagaatgga aatatctagg ctaatcgata
    24181 agctagccaa tccgcttgaa cgttctgttc tcaggctgtt ctacttgaat gttcttgacg
    24241 cttggcaagt tgctgaggaa atagataaat caaagactgc agtatacatt ataaggcaaa
    24301 aagccataga acacttagca aatgtggggt aataggtgag cacaaaaaaa cgcctagaac
    24361 aatctaagcg ctaaagagta gtggacggtg tgcctgtccc gtcatctcat actatgaagt
    24421 tgcgtagcga cactatcatc tctacctcac ttctctttag actattatac cacaaaggag
    24481 cgaactaatg gagctggata agtttaaaac gatgatgaac gtcagagagc ggatgaccta
    24541 ctttctacgt ttccagagga tggcaggaag tgaaaaccaa gttacgatag atgaagaggc
    24601 ttggaaactt gtcttacctt atcggtggga tttgagcggt gagcatgaaa aagcaatccg
    24661 tgaggggttg gaaatattcg cccaagacat caacagtata gaaaacaaac gagctagaaa
    24721 atactttatt atccattact gttacatgag aaagaaaaca atgagcgaat gcgtagaaat
    24781 ggcagctact agctccacta gctaccaccg atataaacaa atagccgtct taaattttgc
    24841 gagaatccac cagaacggag agctagaagt gtataagtag gcgtttgtgg tgttttgttg
    24901 agaaatgttg agatttaagt gaggggggat gacatgattg aagatttttt gattgatttg
    24961 gagaatatcc aattagagga tatggagata gattttaaca tggatataga catcgattta
    25021 aacatagatt ttgaaataga tgttgacctt gatgatttag atttaacctt actacaagaa
    25081 ttagaagcgt aaatgttggc aaatgtaggc tgaggcttca tattcgtccc ctattttgct
    25141 ttggtttgga ctggacaatt aaaacaccat ggataaacta gaagccctca gaaacgagtc
    25201 taggggcttt tgtgaggtca taatcttata aaccacgcgc ttcatggtat aatataccta
    25261 tcagcaacca gcaataaaaa aagcacgttt aaccgtgcta gtttcttgcc tgctgaactc
    25321 gtcatttatt gcccttttgt ggggcttttt ttgtggactt tttgagaatt tttaagaact
    25381 tttaatgatt tctaatcaaa tgagattttt caaaaagtca gtaatatcaa gggtttaggc
    25441 gctttaaaca agtttaaaag cgtatagatt acaatctaac acaaaaaggg ataaagtgct
    25501 aaccctctaa ctaagggttc tcagtcaata attttattca tttttcgctc aaaatcatat
    25561 cgccccatca tgacaacatg ctcacaatta ctgcatttta ttttgatatc tgctcctaca
    25621 cgtgtaattt cccaacaatt agccttttta ccagtcgact tgattgtaca agcgtgtgat
    25681 tttttcatct caacaaaatt tccaacttga tacatactac tctccttttc tttttcgatt
    25741 atatcataaa agaggcgagc caggctcaac ctctttcact taatttgtac gaactggtgt
    25801 aatgagctgc atgaagtctt cgtcagtatc tgctggcaca agagtaaatg gacgaacagc
    25861 tgagataaag ctaatggtca ccttttcgct atttaaagct ttaagagaat caatcaagta
    25921 agttgggttg aaactaatgg tcaaatcttc accagtaacc tgatcagtat cgatttcttc
    25981 gtttacttta ccaacttctg gagagtgaac atgggcgcta acaaccccat ccttaatttc
    26041 aagtttcaca gtaccatttt gagtcgcact tgataaaaga cgggcacgct ccattgactg
    26101 gcgtaagttt accacattaa aagtaatagt agtgttaaag tctgttggaa tcaagcgatc
    26161 tgtatcagga tagtttcctt ctaggagacg agtatagaag ctaatatttt cgcttctaaa
    26221 gaggatttgg ttattggcaa agaaaatctc tacagtttcg atatcatctg taaataccgc
    26281 tgaaaattcg cgtagagaac ggctaggaat tacgacatca aaatcatcac tatttttttc
    26341 aagagtcaat tttttctggc ttaggcgatg agagtctgtt gcaactgttt ttaactcttt
    26401 gtgttgactc aatacgaagt ggacacctgt taaaatcgga cgactctctt gtgtacttgc
    26461 agcaaaggct gtttcattaa taattttctt gagtaatttt gtttcaagta ttaaaggagt
    26521 gcttgctgaa atttcttgga ttcgtggata ttgttcgcta tcttttcctt ttagggtaat
    26581 ttctgatttg ccactggtta aaacaatttg attttgttca atttctttaa aatcaagagt
    26641 tacatcaggt aaactagata ctacattgat aaagaaagaa gcttcaagaa ggatcgaacc
    26701 taaagaagta attaacaaac cagcatcttc atttttttga gaaataaaat tttcaattga
    26761 aatttgacca tttgaaccaa ttaaagtaat accttcattg gtcacgtcaa tttttactgt
    26821 tgataaaata ggaatggcat ttttagaact aatagctctc ttagtagtat ttaatgcttg
    26881 tagaaataaa tttttattaa ttgaaaaatg aatcatggat tctcctttat ttatttttag
    26941 tattagaaag ataatagtaa taatagagtc tgtgaaatct gtggaaaaca gcctttaaac
    27001 aagtcatatc aagtttttta gcttgtttaa aaaatgtgga taaaaaagat aaaaaactaa
    27061 aagttatcca caaattattt gattttcttt ttgattgatt caatttctaa acgtaaatta
    27121 tcgtcttgat caatcaaaga ttttattttg gcatgggcat gaatgactgt ggtatgatct
    27181 tttcccccaa attccttccc aatttttgga agactattat ctgttagttc tctagataaa
    27241 tacatggcta cttgacgggc caaaacaata ttttgaaggc gtctacttcc cttcatttct
    27301 ttgatactaa caccataaaa gttaccaact tcagtttgga ttttatcaat tgggatgacg
    27361 agcatttggc taacatcttg tttgcgggct ctaatggctt ctgcagcaat atcaatagtg
    27421 atatccttga ttttttttac tctggcaatt aaagtgatgt cgttgatggc tccctcaaga
    27481 tctcgaacat ttgaatcaaa ttgcccagct aggtattcta gagtatcact ttggaaattg
    27541 tagcctaaat gttccgtttt actttgtaaa atggcaatac gtgtttcaaa gtcagggggt
    27601 gtgatagttt gtgtcaatcc ccaactaaaa cgcgtgacaa gcctctcctc gagcccttct
    27661 agatgttttg gactacgatc actcgttagg acaatctgtt tttgcttgtc atgaagggcg
    27721 ttaaaggtat tgaaaaattc ttcctgagtt gcgacttttt ttccgctgag tgactggata
    27781 tcatcgatta acaaaagatc aagactacga taggtctttt taaacttttc catttcccca
    27841 agtcttaggt gatcaagaaa gtcattaata aagctttcgg cagggatata tttaacacgc
    27901 gcattaggaa tattttttag aatttcattt ccaatagcgt ttaataagtg agtcttacca
    27961 aggcctggtc ctccatagat aaaaagaggg ttataggtca gagccaaatc ttcagagaca
    28021 gctaaagcgg ctgacacagc ccaaacattt ccatcccctt gaataaagtt atcaaaggta
    28081 tacttttctt ttaatcccgt atctgaataa ggaatagata ctaactttgg actatagtta
    28141 taaagagtta aatttgtagc ttcttcaact tgtgagctag tcgtatcttg aggtttggtg
    28201 aaaatatagt ggggagttat ttcagcgtca taaatttcaa aaccagctac tacaataata
    28261 tcttttagtt gtttttccca gaccatttcc atttcagagc gaggtagaaa tatagtggca
    28321 acattttcct ctaccttgat gagttcagct tgaatagcat agaaatcata catggatcga
    28381 gtcagtcttt cttgtgcaaa ttctaatata cgattccaaa attgtttttc tttcaatcct
    28441 ttctcctcct ttactattta aaagtttaat actagagata ttttaccata gatagcaaga
    28501 attttccaca agctgtgaaa aataatccac aatgttacca aactttatcc acaggttggg
    28561 gataaaagaa gaaattattg atttattaag ctttttatcg aaaaacatag tggataacct
    28621 tgtgagataa aaaaataaaa gaacagcctt atttcaggct gttgataatt ctactatatt
    28681 cttcttgatt tgaaaaagaa ataatgattt ttccactgtc ttttttagat agtttaattt
    28741 ctacatctaa tccgagtagt tttcttaact gtttttcttc attttgtatg aaatgattag
    28801 ttttttgctg tttcttttgt tttttctctg tcagaagagc ttctaatttc cttacagaaa
    28861 tatcttcttc tataatccgt tgaaagaaat agtcttgttg ttccttattt aacccaacta
    28921 gggaacgcgc atgggcttgt gatagtttgc cattttctac ttctgaaaga atctgttctg
    28981 gcaaggaaag taaacgaatg gagttgctga tatatggacg agacttgccc atcttatctg
    29041 caatttcagc atgggtgaat cctttctcta cgagagattc ataggcgcgt gcttcttcta
    29101 ttgggtttaa attttctctc tgtaaatttt caataatgga ctggaccatc atctcttggt
    29161 ctgaaatctg tttaacaaca gctgggatag accgtagacc agctaaaagt gaagcccgat
    29221 agcgtctctc tcctgcaagg atttcataac caataacagg agattgacga acaataatcg
    29281 gttgaatgac cccattttct ttgatagact gtgctagttc atctagtttt tctctatcaa
    29341 attcttttcg gggttgatag ggattttttt gtatatctgt gatagaaatc atttcaaatt
    29401 tttccatgat tctacactaa cacatctttt ctcttatgta aagctttctt tacatagatg
    29461 tcaattaaga ttctaaatca cctgaactct tgttaagttt gatagaggta gtttcttctt
    29521 tcccgttacg atagtaggtt atcttaatgg tgtctccgat agaatggttg taaagagcac
    29581 tttgtaagtc tgttgatgaa gcaatctctt tgtcatctac ttttgtaatt acatcgtatt
    29641 tttcaaggtg accattggca ggcatattac tttgtaccga acgaacaact acaccagatg
    29701 taacattact tggaatattg agtcttctga tgtcgcttgt actcacatta gataaattaa
    29761 ccatctggat tcccaaagct ggacgcgtca cttttccgtt tttttctaac tgttcaataa
    29821 tattgatagc atcatttgca ggaattgcga aaccaagacc ttctacagat gttcctccat
    29881 ttgtagcaat tttacttgag gtaattccga taacctgccc ttgaatattg atcagtgggc
    29941 cgccagagtt acctgggtta atagcagtat cagtttggat ggcttttgta gaaatagctt
    30001 gtccatcttc cgattttaag gatacatttc tattgagact ggatacgata ccttgagtga
    30061 cagtatttgc atattcagaa cctaacgggc taccgatggc aatagcagtt tctcctacag
    30121 ttaacttact agaatcacca aactcagcta ctgttgtcac tttttctgaa gagattttta
    30181 cgacagcaat atcagagaaa gtgtcagctc cgacaatttc tccaggtact ttagtcccat
    30241 ctgacaatcg aatatctact ttgctggcgc catttataac gtgattgttg gtgacgatgt
    30301 aagcttcttt atcattcttt ttataaataa ctccagatcc ttcactagag attcgctgag
    30361 aatctgtgtc agtatcatca ttgccaaata cgctattttg tctgtttgcc gaataagtaa
    30421 taacagaaac aacagcatct tttactttgt taacagcctg tgttgttgaa ttttcgttct
    30481 tataggcagt ttgtgtaata gtactattgt tgttagagtt gtttacacta cttttttgag
    30541 ttagttgagt tattgaaaaa ctacccaagg ctccactaaa aaagctaatg acgataacga
    30601 ctaataattg aaaccatttt ttgtaaaatg tttttagatg tttcatattt gcctccatat
    30661 gtttgaatta ctgaaagtat aaactgacta gcttaattat aacttaaaca caaaagtttt
    30721 acacaaactg tggataactc ttttgaaact gtgattttct taattgaaat ctatttttta
    30781 ttttgtgaat aagatgtgaa aaaatagaga atatgttaga atagagtcat gaaaattaaa
    30841 gttgtaacag ttgggaaact gaaagaaaag tatttaaaag atggtatcgc agagtattca
    30901 aaacgaattt ctagatttgc taagtttgaa atgattgagt tatcagatga aaaaacacca
    30961 gataaggcca gtgaatcaga aaatcaaaag attttagaaa tagaaggtca gagaatttta
    31021 tcaaaaattg ctgaccgtga tttcgttatt gtgttagcca ttgaagggaa aactttcttc
    31081 tcagaagaat ttagtaagca gttagaagaa acttctataa aaggattttc tactcttact
    31141 tttattattg ggggaagttt aggattgtca tcatctgtaa aaaatagagc caatctttct
    31201 gtcagttttg gtcgcctaac cttaccccat cagttaatga gactagttct tgttgaacaa
    31261 atctatcgcg cttttacgat tcagcaggga ttcccctacc ataaatagaa aattgacttt
    31321 taattgaatt tttggtagaa taattgtatt aggtctcata gctcagctgg atagagcatt
    31381 cgccttctaa gcgaacggtc gcaggttcga atcctgctgg gatcaatata atagcaaagc
    31441 tgggaatttt cccggctttt ttcttaaaaa agtacacttt gggagaaaaa aatgacagtt
    31501 gagagaattt tatctaaaac gaaattccat tttgtataat ggtttttgta agttagctta
    31561 caagaaaaaa cattttagga gattttatta tgaaaaacac agttaaattg gaacagtttg
    31621 tagctttgaa ggaaaaagac ttacaaaaga ttaaaggtgg ggagatgagg ttgtcaaaat
    31681 tcttccgtga ttttatttta caaagaaaaa agtaatgaaa taaggggaaa gagtaatgga
    31741 tttatttgga tttgggacgg ttattgttca ttttttaatt attagtcaca gttaccattt
    31801 tatttgtaaa ggtcaaataa atagaaaaga attattcgtt tttggtgctt atacattact
    31861 aacagaaata gtatttgatt ttcccttata tattctatat ttagatgggt tagggattga
    31921 aagattttta tttcctttgg gattatattc ctattttcga tggatgaaac agtatgagag
    31981 ggatagagga ctattcctaa gtttactact atctctttta tatgagagca ctcataactt
    32041 tctgtccgta actttctcct ctataacagg agataatttt gttttacaat atcatttccc
    32101 attctttttc gttgtgacgg tgttaaccta ttttgttaca ttaaaaatca tttactattt
    32161 ccatttggaa ctagcctatt ttgacgagga ctacctttat cctttcttga aaaaagtatt
    32221 ttttgcttta ctattgctac atattgtatc tttcgtttca gatatggtaa gtacgattaa
    32281 acatttgaat agttttggaa gtattttgtc atctattgtc tttatctctc tccttttgac
    32341 cttctttgca atgaattctc ataaagttca aatggagaaa gagattgctt tgaagcagaa
    32401 gaaatttgaa cagaaacatt tacagaatta cacagatgaa attgttggtc tgtataatga
    32461 aatccgtggt tttcgacatg attatgctgg aatgcttgtc agcatgcaga tggcaattga
    32521 cagtggtaat ttacaggaaa ttgacagaat ttacaatgaa gttttagtca aagcaaatca
    32581 taaattgcgt tcagataagt acacttactt tgatttgaac aacatagaag actcagcttt
    32641 acgaagtttg gttgctcagt caattgtcta tgctcgaaat aatggtgtag agtttacact
    32701 ggaagtaaaa gatacgatta ccaagcttcc aattgaacta ttggatttgg ttcgtatcat
    32761 gagcgtttta ttgaataatg ctgtcgaagg atcggctgat agctataaaa agcagatgga
    32821 agtagcagtt attaagatgg aaactgaaac agttattgtg attcagaatt catgtaaaat
    32881 gacgatgact ccttcaggag atctatttgc cttaggattc tccactaagg gaagaaatcg
    32941 cggagtcgga ttaaataatg tgaaagaact actagataag tacaacaata ttattttaga
    33001 aacagagatg gaaggcagta catttagaca aatcattaga tttaagaggg aatttgaatg
    33061 aaagttttaa ttttagaaga tgttattgaa catcaagtga gactagagag aatattggat
    33121 gaaatttcga aagaatcgaa tattccaata tcatacaaga caacgggaaa agtccgtgaa
    33181 tttgaagaat acattgaaaa tgatgaagta aatcagcttt atttcctaga tatcgatatt
    33241 catggaattg agaaaaaggg atttgaagtg gctcagctca ttcgtcatta caatccttac
    33301 gctattatcg tctttatcac tagtcgatca gagtttgcga ctctaaccta taaataccag
    33361 gtatcagccc tagattttgt tgataaggat atcaatgatg agatgtttaa gaagagaatt
    33421 gagcaaaata tcttctacac gaagagtatg ttacttgaaa atgaagatgt tgtagattat
    33481 ttcgactaca attacaaagg aaatgattta aaaattcctt accatgatat tttgtatatt
    33541 gaaacaacag gggtctctca taaattgcgc attattggta agaattttgc aaaagagttt
    33601 tatggtacca tgacagatat tcaggaaaag gacaaacata ctcagcgatt ttattctcct
    33661 cacaagtcat ttttggtaaa tataggcaat atcagagaaa ttgatcgaaa aaacttagaa
    33721 attgttttct atgaagacca tcgttgtcct atttcaagat taaaaattag aaaattaaaa
    33781 gatattttag agaaaaaatc tcaaaagtga ttgacaatta gcaagaaatt gatataatgg
    33841 ttatatctgc tacagataga aggtccgttg gtcaaggggt taagacaccg ccttttcacg
    33901 gcggtaacac gggttcgaat cccgtacgga ctattttatc cgccatagct cagttggtag
    33961 tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc ctactggcgg agtatagata
    34021 aaagggaaca cagctgtgtt cctctttttg tatcaatttg tatcaccaag cattttcata
    34081 aggaagtctg ttatttcttg agaactttct ttttttccat gtgcaatcca agtttggcag
    34141 acaccaaaaa gtgcatgagt tagatagatg ctactatatt ctaattcggt ggtatttaga
    34201 ttcagttgca taaatcgctt ttgtaaatct gtactaagca tgatatgaag tttatttcgt
    34261 aagaaatttt ggatttcttt agtcccattt tcagaaagaa gggcagccag aagtggttct
    34321 gactctagat attcaaaaac ttctaaaata gcgtctcttt tgtgatgagc atgtttttga
    34381 aaaatatatt caaatgtatg gaatagcttg ctttgatagt gctcaatcat atcatactta
    34441 tccttatagt gagtatagaa gctggaacga ctaattccgg ctttttctac taatttgaca
    34501 gtagaaattt tatcaaatgg ctgttccatc agtaattgta ccatagcatt ttcaatagtt
    34561 cgctttgttt ttaagcgttt gttactttct tgcatatttc ctccttgtaa acaaattaga
    34621 ctatatgtct aaaaatagat tttttatctt gtaatttaga ttttttaatg tataatctat
    34681 tatatcaaaa ttttagacaa tatgtttaaa aaaggagaaa ctaagtttaa agaatggaaa
    34741 gcaatttaaa aaaaaccaac ctttattatt gtcatgatcg ggatttctct tattccagat
    34801 ctgtacaata tcatattttt gtcatcaatg tgggatccat atgggcaatt gtctgactta
    34861 cctgtggcag ttgtaaataa tgataaagag gcttcctata atggtaatac tatggcaata
    34921 ggaaaagaca tggtgtccaa tttaaaagaa aataaaacct tggattttca ttttgtagat
    34981 gaagaggaag gaaagaaggg attggaagat ggcgattact atatggtagt gactttacca
    35041 agtgatttat ctgaaaaaac aactacatta tccaatattc aatcgacagc agcttatcaa
    35101 tcattgacaa gtgagcaaca aactgagata agtgattctg tatctcaaaa ttcaactgat
    35161 agtattcaat cggctcagtc aattgtagct ttagtacaag atttacaggg aagtttagaa
    35221 aacttacaaa atcaatcttc taatctttcg actttaaaaa atcaatctaa tcaagtatca
    35281 cctattactt ctacttcttt gataggattg tcaagtggat taacagagat acaaggagat
    35341 gttactagca aattagttcc tgccagtcag tcgattgcat caggtgtaaa cgcatatact
    35401 acaggtgttg ataaagtttc tcagggcgca agtcaactaa gtgaaaaaaa tgccaccttg
    35461 acaggtagtt tgaataaact agtttcaggc tcaaacacct tgacacaaaa atcttctaga
    35521 ttgacagcag gagttggtta attacaatca ggatctgggt aattagcaga caaatccagt
    35581 cagttacttt caggtgcttc tccattagag aatagagcta ataaattggc agatggatct
    35641 gggaaactag cagaaggtgg aacaaagtta acttctggat tggaagattt acagacagga
    35701 cttgcttctt taggacaagg actaggtaat gctagtgatc aactcaaatc agtatcaaca
    35761 gaatctaaaa atgcagagat tttgtcaaat ccactcaatc tttcaaaaac agacaatgat
    35821 caagttcttg taaatggaat cgcaatagct ccttatatga tatcagttgc tctttttgtt
    35881 gcagcaatat caacaaatat gatatttgcg aaattgcctt caggacgtca tccagagagc
    35941 cgttgggctt ggttgaaatc tcgagctgaa ataaatggta ttatagctgt tttggcagga
    36001 attttggtat atggaggagt tcagcttatt ggtttaactg ctaatcatga gatgagaata
    36061 tttattctca tcatcctaac aagtttagta ttcatgtcta tggtgaccac tttaacaacg
    36121 tggaatagcc gtataggagc ttttttctca cttattttgc ttttactaca gttagcatca
    36181 agtgcaggta cttatccact tgctttgaca aatgatttct ttagatctat taatccctgg
    36241 ttaccaatga gctattcagt ttcgggatta cgacaaacaa tctccatcaa caagtcattt
    36301 tcctagctgt catactagct ctatttactg gtttaggtat gctagcctat caacataaga
    36361 aaatagaaga agattaaaaa aatcgaccga ttaactggtc gattttttat gccttagatg
    36421 actttcgtct gtgattatag attccaaata gtaagagaga agtaaaggaa cagattgctc
    36481 cagtaataaa accattggga atgaaggaaa gtgtaatagt tcctttcccc ttgggaatgt
    36541 caactttcat aaatccagtt tgagcttgtt taatttctat tttcttacca tcttggtagg
    36601 cagaccaacc tttgtcataa ggaatggtga agaaaataga tgtatcttgt tggacatcat
    36661 atgtagcaaa aaccttgttt ttagaagttg atactgtgac aggttgttct ttaatttttt
    36721 gaattgcctc ggtgaaagtt ttggtatcta aacgatagaa ggtaggagat tcaaatgata
    36781 cttgtgaatt tccagggaaa ctaacattga tattgaaagt ttttttctct ttagtatatc
    36841 ctagattaaa gaaggagaag acattatcag ttgtaaaagt ctttttttca ccatttacaa
    36901 ggatgtcaac cttcttttgt ttatcgttag aaaagtgaag gtttatgaaa gagagataaa
    36961 cttggctgtt ttctggaact tcaatttgat actggattgc tgcatcttca tttgaagaac
    37021 ttgtgacact aatcaaatca ttagtatttt ctattttttc tgttttttca taaggtattg
    37081 gagaaaaata atcaaaattg acgttagcaa gttgatttaa aaatgaggcc tgattatcca
    37141 aggtatgttc attgaacttg acatcattgt aaacagattg actagcaact gcaatcggaa
    37201 gagagtattg attttcatat agggtaagat tatctttttg atagatatct ttaaagccat
    37261 acttatcaat aggactgtct gagatattgt actggatacc aaataaacta tcagccaaaa
    37321 tactattatt tgcatatcgg agattgagat tagtcccaga ggatttaaaa ccaagtttat
    37381 ctaaagtaga gcttgatgaa cgatttcgaa cagatgaaaa ttgagagatt ccattgtagt
    37441 tgaatttcat actgtcattt cctgtctgag tttgtagttt ttcagtacga gtaaattgat
    37501 ttccaatata tgttgagaaa gattccatag ctgggatatc tcgactataa gcacttcgag
    37561 aagcaaatcc ccattcctta gcaattccgt ccatttgaga tgaagcattt aaactcattt
    37621 caaccagtat aaataaagag attagaatgg caaatagatt cacagatata aactttttga
    37681 taactgcaag gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc agaatattca
    37741 aatctgttaa aaaagaataa tgcgatttta gatagatggt agctaaaaat cctgttacta
    37801 caagaaaaag cgaaactaaa aaattccaga ctttaagttc tttcagacgc tttaagactt
    37861 ctgctgctgt gtaaattaac aaggtagaga aaatccaagc atagcgatgt aaaaacatgt
    37921 ttggagtatg catgccttgc caaaataagt caagagcttc tatgtaaaag cttgcaatta
    37981 gaaatgcaaa gaatattata tatatgagtt tcacgtgaaa cctaatagat ttcagcgtaa
    38041 aaaataaaat ggtcaaaata aagggaagta gtccaacaaa aatcattggg atggccccat
    38101 actttgttgt gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga taccagctac
    38161 tttcagtttg aaactttgta acttcagtca atttttcccc atgtgtctgt aaatcaaaca
    38221 gagtgggaag agtcataatc aaactagcca taccagctaa aaaggagata actatgaaat
    38281 caagaacaga tgattttcga gtcttaaagt cccacgaaat ttgacagaga taccagaaaa
    38341 taagaaacaa tactgtcata tatccaaaat aataattttg aataaataag attgacagac
    38401 ttgtaaagta caataggagt ttcttttcag ttatcagtag atgtaaacca gttataatta
    38461 aaggaatcaa gataaaaaca tctagccagg tttttatctc taattgactg acagtgaaac
    38521 ccatcagagc ataggaagta gataaggcta gttttaaagt ctgagggata gattgaaaca
    38581 atttattcaa actaaaaaag gttgacagac caatcaatcc aaattttaag agagtggtca
    38641 gatagacagc atctggcata ttcgttagat caaaaaagta aactagaggc gcgagaaaac
    38701 tacccaagta ataactagat agggcataga agtttagccc tagaccactt gtaaaggtgt
    38761 aaaacagact actatttcca tgtaggatat ttcgtaaggc tacatcaaaa ataacgtatt
    38821 gatgaaagcc atctcctaat agaggagagt tgtcgctatt ccagtagata ccttgagata
    38881 gatatactcc agacataatc actacaggaa tgatgaaaga aataaaatag gttcgatatg
    38941 tttttaaaaa tgatttcatg ttacctcgta gaatgataga aaactcagtt ggttaaccca
    39001 actgagtttt gaagttttat ttagtctttc caaagttctt taacttttgc ttgtacttct
    39061 gcattttcta ggaattcatc gtaggtttca tcgatacggt caatgacgcc atttttagat
    39121 aagacaatga tatggttagc caaagtttga ataaattcgt ggtcatgact agcaaagatg
    39181 attgattctt taaagttttt caatccatca ttcaagcttg agatagattc caagtccaag
    39241 tgatttgttg gatcatcaag tacaaggaca tttgatttta agagcatgag ttttgaaagc
    39301 atgacacgaa ctttttctcc ccctgacaag acatttacag gtttgttaac ttcatctcca
    39361 gagaagagca tacggccgag gaaaccacgt aggaaagtat tgtcatcttc ttctttactt
    39421 gcgaattgac gcaaccagtc aagaattgat tctcctcctg caaaatcagc tgagttatct
    39481 tttggtaggt aagattgact agttgtaact ccccacttga cagttccttc atagtcaata
    39541 tctcccatga ttgcacgaat taatgcagtc gtttgaatat cattttgtcc aataagtgct
    39601 gtcttatcat ctggacgcaa gatgaaacta atattatcca agatagtttc accatcaatc
    39661 tttacagtta gattttctac tgtcaagaga tcattaccaa tctcacgttc cgctttaaag
    39721 ttgataaatg gatatttacg actagatggt acaatctctt ctagctcaat cttatcaagc
    39781 attttcttac gtgatgttgc ctgccttgac ttagaagcat tggcagagaa acgagcaacg
    39841 aattcttgca attgtttaat tttttcttct gctttagcat tacggtctgc tagcaattta
    39901 gcagcaagct cagaagattc cttccagaag tcgtagtttc cgacatagag tttgattttt
    39961 ccaaagtcaa ggtcggccat gtgagtacaa actttgttta agaagtgacg gtcgtgggat
    40021 actacgataa ctgtgttatc aaagtcaatt aagaagtctt ctaaccaagt aatcgattgg
    40081 atatccaaac cgttagtagg ctcgtccaag agaagaacat ctggtttacc aaaaagtgct
    40141 ttggcgagga gaacctttac tttttcaccg ttggccaatt cgctcatgtt ttggtagtgt
    40201 aattcttctg gaatgtttag gttttgaagt agttgagagg cttcactctc tgcttcccaa
    40261 cctccaagtt cggcaaactc tccttcgagt tcggcagcac gaaccccgtc ctcgtctgag
    40321 aaatcttcct tcatgtagat agcatctttc tctttcatga tgctataaag tttttcattt
    40381 cccatgataa cgacatcaat ggcacgttca tcttcgtagt caaagtgatt ttgacgaaga
    40441 acagagagac gttcatctgg accaagagag atgtgaccag tagtaggttc gatatctcca
    40501 gctaaaattt ttaaaaaggt tgattttccg gcaccattag caccgattaa tccgtaagta
    40561 tttccttctg taaatttgat attgacatca tcaaaaagtt tgcgatcact aaaacgtagt
    40621 gaaacatcag atactgtaag caatattttt ctcctatatg tgtaatatat ttattctact
    40681 agaaaataca gaaatattca aatttttatt tatcaatttt gtgtaaatta tatttacagt
    40741 atcctttaca caaatctgta aaaagcaagg ctgatttatt ttgataaatt acggttattt
    40801 cattaaaaaa atgctataat tgaaaggact atatcgaagg agaacaaaat gactaaaccc
    40861 attattttaa caggagaccg tccaacagga aaattgcata ttggacatta tgttggaagt
    40921 ctcaaaaatc gagtattatt acaggaagag gataagtatg atatgtttgt gttcttggct
    40981 gaccaacaag ccttgacaga tcatgccaaa gatcctcaaa ccattgtaga gtctatcgga
    41041 aatgtggctt tggattatct tgcagttgga ttggatccaa ataagtcaac tatttttatt
    41101 caaagccaga ttccagagtt ggctgagttg tctatgtatt atatgaatct agtttcgtta
    41161 gcacgtttgg agcgaaatcc aacagtcaag acagagattt ctcagaaagg atttggagaa
    41221 agcattccga caggattctt ggtctatcca atcgctcaag cagctgatat cacagctttc
    41281 aaggctaatt atgttcctgt tgggacagat cagaaaccaa tgattgagca aactcgtgaa
    41341 attgttcgtt cttttaacaa tgcatataac tgtgatgtct tggtagagcc ggaaggtatt
    41401 tatccagaaa atgagagagc agggcgtttg cctggtttag atggaaatgc taaaatgtct
    41461 aaatcactaa ataatggtat ttatttagct gatgatgcgg atactttgcg taaaaaagta
    41521 atgagtatgt atacagatcc agatcatatc cgcgttgagg atccaggtaa gattgaggga
    41581 aatatggttt tccattatct agatgttttt ggtcgtccag aagatgctca agaaattgct
    41641 gatatgaaag aacgttatca acgaggtggt cttggtgatg tgaagaccaa gcgttatcta
    41701 cttgaaatat tagaacgtga actgggtcct attcgtgagc gccgtattga atttactaag
    41761 gatatgggag aagtttataa tatgattcaa aaaggtagtg aaagagcgcg tgaagttgcg
    41821 ggtcaaaccc tatctgaggt aaaaggggca atgggacttc attactttaa ctaagtttat
    41881 tttacaagaa actatctttt ctatctcgaa gaaaagatag ttttttattt acccctgtaa
    41941 catttgacaa atttttatag aatggtatga tagatacaat ataaaaagag tcaagctcaa
    42001 aaagaaagaa aagaggaaac ttcgaatgtc taattgggac actaaatttt tgaaaaaagg
    42061 ttttaccttt gatgatgtat tgcttattcc agctgaaagt catgtgttgc ctaacgatgc
    42121 agatttaaca actaaattgg cagataattt gactttaaat atcccaatta ttaccgctgc
    42181 catggacaca gttacagaga gtcaaatggc cattgctatt gctcgtgcag gcggtctcgg
    42241 agttatccat aaaaacatgt caattgctca acaagcagac gaggttcgta aggtaaaacg
    42301 ttctgaaaat ggagttatta ttgatccgtt cttcttgacg cctgaacata caattgctga
    42361 agcagatgag cttatgggtc gttaccgcat cagtggtgtt ccagttgttg aaacacttga
    42421 aaatcgtaaa ttggttggta ttttgacaaa ccgagatctt cgttttattt cagattataa
    42481 tcaaccaatt tcaaaccata tgactagtga aaatcttgtt actgctcctg tgggtacgga
    42541 tcttgcaacg gctgagagta ttcttcaaga gcatcgtatt gaaaaacttc cgttggtcga
    42601 tgaagaaggc agtctttctg gtttgatcac tatcaaagat attgaaaaag ttattgagtt
    42661 tccaaatgcg gctaaagatg agtttggtcg tcttctagtt gcaggtgcag taggtgttac
    42721 ttcagataca tttgaacgtg cagaggctct ttttgaggca ggagcggatg cgattgttat
    42781 tgatactgca catggtcatt ctgcaggtgt cttgcgtaaa attgccgaga ttcgtgctca
    42841 tttcccagat cggactttga ttgctggaaa tattgctact gctgaaggtg cacgtgccct
    42901 ttatgaagcg ggtgtagacg ttgttaaggt tggtattgga ccaggttcta tctgtactac
    42961 tcgtgtgatt gctggtgttg gtgttccgca agtaacagct atctacgatg ctgcagctgt
    43021 tgcgcgcgaa tatggtaaaa cgattattgc tgacggtggg atcaagtatt ctggagatat
    43081 tgtaaaagca cttgctgcag gtggaaatgc tgttatgctt ggatctatgt ttgctggaac
    43141 tgatgaagct ccaggcgaaa ctgaaatctt ccaaggacgt aaattcaaga cttaccgtgg
    43201 tatgggatca attgctgcta tgaagaaagg ttcaagcgac cgttatttcc aaggttctgt
    43261 caatgaagca aacaagcttg ttccagaagg aattgaaggt cgtgttgctt ataaaggagc
    43321 ggcagctgat attgttttcc aaatgattgg tggtattcgc tctggtatgg gttactgtgg
    43381 tgcagctaac cttaaagaac tacacgataa tgctcaattt attgaaatgt ctggtgctgg
    43441 tttgaaagaa agccatcctc atgatgtgca aattactaat gaggcaccaa attattctat
    43501 gtaaaaaaca atgaaaagaa ctccagtgaa aacaggagtt cttttacaat gttgtcaatt
    43561 tctatttaca gcagctttac catcctgaat agtgaagata cttagatttt ctggcagatt
    43621 ttgaagatgg tctaagcttg ttgttgtgat aaaggtttgg attgattgag aaatcgtttc
    43681 taataatttt aactgtctag tgttgtcaag ttcactcatc acatcgtcaa gcagtaatat
    43741 cggagattct gtggtaatgc tttccattaa ttcgatttct gctaatttta tcgagaggac
    43801 gagactacga tgttgacctt ggcttccgaa actagcatcc atcccattta tataaaaaga
    43861 aatgtcatct cgatgaggac cgacaccagt attcttttta aataaatctc tggatctact
    43921 tttttctaaa gcaattttga aagattcgga taagttttgt ttgtcagtta tattgacaga
    43981 agattgatag gatattgaca actcttcgat ctgattagag agttcaaaat gtttcttacg
    44041 cccaaatgat tctagttttt ttatgaaatc taagcggtga ttcattacac gacatccata
    44101 atcaactagc tgatcatcta acacagaaag gaatgtttca tctatttttt gagctgattt
    44161 taggtaagtg tttctttgct ttaggatgtg gttataattg gttaagtcag ataaatagat
    44221 tggcttaatt tgcccaagtt ccatatcaat gaattttcgt cgaatcgaag gtgctccttt
    44281 aattagttgt aaatcttcag gagcaaataa gacaacattc atgtgtccta cataatctga
    44341 aaggcgtgcc tgttttaagt gattaacttt tgttacacgg cctttttgtg ttagttcgat
    44401 ttctagggga atggatccag tttttttctg aacgagacct gaaagatgaa gttgttcctc
    44461 atcaaaatga atgagatttt tatctgttcg agttcgatga ctacgcgtta aggctaaaaa
    44521 atagatagcc tctaacatgt ttgtttttcc ttgtgcatta cgtcccaaaa agacattcaa
    44581 tttaggatta aagtctattt tcgtttcttt gtaattacga aaagtcttga gagatagatg
    44641 ttgtagccac atgattatct accagggaat cgtggagctt gttggctttt aggtgatgaa
    44701 gcaggtttcg atttgtcttt tttaactccc ttattcatct ttttgacaag tttagcgatc
    44761 cgttcttttt caactttatc agcttggtat tcatcttgtt cttcagaagt aggttgtgtc
    44821 aacaagatgt caatgttcat gtcagggatg tcaactttat cgccaatacg aagttttttt
    44881 ccacgacaac tctctaattc cctattaaag taaacagaat gttcagagag aaatgattta
    44941 atagctcctc cgctatgtgt aattccaagt tctttgagta gtgcttggag ggtaataaat
    45001 tcttcaaata atttgtattc cataattcac ctcaatcttt ggtattatac catattttcc
    45061 taaaaatagt gagagagaca gcgagaaatg taagcgattt ttatttcaaa agtgttacag
    45121 ggaacaagaa aatttcaggt tttcgtgata taatagaagt ctgtatataa ggaggtaaat
    45181 catggagtta gtgcatggaa tttcaacaca ttttatccaa tcaaaaaagt ttaaaacaaa
    45241 caaaattacc gtgcgtttta ccgctccatt atcccttgat acgattgcag gtcacatgtt
    45301 gagtgcaagt atgctagaga ctgctaatca gatgtacccc acttctcaag atttgaggag
    45361 acacttggcc agtctatacg gtacagatat gtcaaccaat tgtttcagaa gagggcaaag
    45421 ccacattata gaattgacat ttacctatgt tcgtgatgag tttttaagta ggaaaaacgt
    45481 gctaacctct cagattttgg aacttgtaaa agaaactctt ttttcacccg tagtagttga
    45541 taatgggttt gatccggcct tatttgaaat tgagaaaaaa caattgctag caagtttagc
    45601 agctgatatg gatgattctt tttattttgc acataaagaa ttggataaat tgttttttca
    45661 tgatgaacgt cttcaattgg aatatagtga tttacgaaat cgtattttag ctgaaactcc
    45721 acaaagttct tattcttgtt tccaagaatt tttagccaat gatcgaatag atttcttttt
    45781 cctaggtgat tttaatgagg ttgaaattca aaatgtatta gaatcatttg gctttaaagg
    45841 tcgaaaagga gatgtgaagg ttcagtattg tcaaccttat tctaatatcc ttcaggaagg
    45901 tatggttcgg aaaaatgtgg gacaatccat tttggaatta ggttatcatt accgttctaa
    45961 atatggtgat gagcaacatt tacccatgat tgtaatgaat ggtttacttg gtggatttgc
    46021 tcactctaag ctctttacaa atgtccgtga aaatgctgga ttagcttata ccatttcaag
    46081 tgagcttgat ttatttagtg aattcttgag gatgtatgct ggtatcaatc gagaaaatcg
    46141 taaccaggct cgtaaaatga tgaataatca actgcttgat ttaaaaaaag gttattttac
    46201 agagtttgag ttaaatcaga ccaaggaaat gattcgttgg tcgttgttac tttctcaaga
    46261 taatcaatct tcattgattg aacgtgctta tcaaaatgcc ttatttggaa tatcttcagc
    46321 agactttaaa ggttggattg caaaactcga gcaagttgac aaagatgcta tttgtagagc
    46381 agctaataat gtgaaactac aagcgattta ctttatggaa ggaatagaat gacaaaggtt
    46441 gtttttgaag aaaaatacta tccagctgta aaagaaaagg tttatcgaac tcgtttggcc
    46501 aatggattga cagttgctct tttgcctaaa aaggaattta aagaggttta cgggagtgtc
    46561 actgtacagt ttggttcggt agatacgttt gtcacagaag ttgacggaga tgtaaaacaa
    46621 tatcctggag gaattgctca ttttcttgaa cataaattat ttgagagaga agattctagt
    46681 gatttgatgt cggcttttac gagtctaggt gcagatagta atgcctttac aagctttaca
    46741 aaaacaaact atcttttttc agcaacggat tattttttag aaaatttaga tttacttgat
    46801 gaattggtaa catcagcaca ctttactgaa gcttccattc tgacagagca ggatattatt
    46861 cagcaagaac gagaaatgta ccaagatgat ccagattcgt gtttattctt ttcaacttta
    46921 gcgaatttgt atcctggtac acctttagca actgatatag ttggaagtga ggagtccatt
    46981 tcccaaatca atctaactaa tttgcaagaa aattttacaa agttttacaa acctgtaaac
    47041 atgtctctgt ttttagttgg taattttgat gtggagcgag tacaggacta ttttgaaagc
    47101 aaagaactga aagattcaga ttttcaggaa gtagcaagag aaaagttgtt tttacagcct
    47161 gtaaagccaa cagatagtat gagaatggaa gtatcttctc ccaaactagc gattggagtt
    47221 agaggtaagc gagaagtttc tgaagcggat tgctatcgac atcatatttt attaaaatta
    47281 ttgtttgcaa tgatgtttgg ttggacttcg gatcgttttc aaaaatgtta tgaatcaggt
    47341 aaaattgatg catccttatc tctggaagtt gaagtaacaa gtcgctttca ttttgtcatg
    47401 ttgacaatgg atacgaaaga gccagttgct ttgtctcatc aatttaggaa ggctattcgt
    47461 aattttacaa aggatttaga tattacagag gaacatttag atattatcaa aagagagatg
    47521 tttggcgaat ttttcagtag catgaactct cttgaattta ttgcaacgca atatgatgct
    47581 tttgaaaatg gtgagacaat ttttgatttg ccgaaaattt tacaggaaat tactttagag
    47641 gatgtccttg atgctggaca tcatttaata gatgatggtg acatagttga ttttacaata
    47701 ttcccatcgt agtaacctat tataatagac actagaaaga agggatgaca agtatgagaa
    47761 aaaaaacaat tggagaggtt ttacgattag ctagaatcaa tcagggattg agtttagatg
    47821 aattgcagaa aaagacagaa atccagttag atatgttgga agcaatggaa gcagacgatt
    47881 tcgatcaact tccaagtcct ttttacacgc gttctttctt gaaaaaatat gcatgggctg
    47941 ttgagttaga tgaccaaatt gttttggatg cttatgattc tgggagtatg attacttatg
    48001 aggaagtaga tgttgatgaa gatgagttga caggtcgtag acgttcaagt aagaaaaaga
    48061 agaaaaaaac atcattttta cctttatttt attttatcct ttttgcttta tcgattttaa
    48121 tttttgtgac ttattatgtt tggaactata ttcaaactca accagaggag ccttctcttt
    48181 ctaattacag tgtggttcaa tcaacaagtt caactagctc tgttccccac tcctcaagta
    48241 gtagttcttc tagtatagaa tcagctataa gtgtatcagg cgaaggaaat catgtagaaa
    48301 tcgcttataa gacaagtaag gaaacagtta aattgcaatt ggcagtttca gatgttacaa
    48361 gttgggtcag tgtttcagaa agcgaacttg agggcggtgt aaccttatcg ccaaagaaga
    48421 aaagtgcaga agcaacagtt gcaactaaaa gtcctgtaac aattacgtta ggtgttgtaa
    48481 aaggtgttga tttgacagta gataatcaga ctgttgattt atcgaaatta acagctcaga
    48541 ctggacaaat cactgtaacc tttactaaaa attaaggaaa aacgaatgaa aaaagaacaa
    48601 attcccaatc tcttaacaat aggtcgaatt ctctttatac ctatttttat ctttatttta
    48661 acgataggaa attcgataga gagtcatata gttgcagcta ttatctttgc tgttgccagt
    48721 attaccgact atttagatgg atatttagct cgtaaatgga atgtggtcag taattttggt
    48781 aaatttgcag atcctatggc ggataagtta ctagttatgt cggcttttat tatgttgatt
    48841 gagttaggta tggctccggc ttggattgtt gcagtgatta tctgtcgtga gttagctgtg
    48901 acaggtttaa ggcttttatt ggttgaaact ggtggaacaa ttttagcagc agcaatgcct
    48961 ggaaaaatta aaacttttag tcagatgttt gctattattt tcttgctatt acattggact
    49021 ttgcttggtc aagttctact ttatgtagcc ttatttttca ctatctactc tggctatgac
    49081 tatttcaagg gtagtgccta tgtatttaaa gggacatttg gttcgaaatg aaatcaataa
    49141 ttgatgtaaa aaatctttct tttcgctata aagaaaatca gaactactac gatgtgaagg
    49201 atattacgtt tcacgtgaaa cgtggagaat ggctttcgat tgtagggcat aatggtagtg
    49261 gtaaatcaac gacggttcga ttaattgatg gcttactgga agcagaatcc ggagagattg
    49321 taattgatgg ccaacgtttg actgaggaaa atgtttggaa tatacgtcgt caaatcggta
    49381 tggtttttca aaatccagac aatcaatttg ttggagcgac tgttgaagat gatgttgctt
    49441 ttggtttgga aaatcaggga ctttctcgtc aagaaatgaa aaagagagtg gaagaagctc
    49501 tggctttagt tggcatgttg gactttaaaa agagagagcc agcgcgtcta tcaggtggcc
    49561 aaaagcaacg tgtggccatt gcaggtgttg tagccctaag accagctatt ttaatcttag
    49621 atgaagcaac gagtatgttg gatcctgagg ggcgtagaga acttattggg acagtaaaag
    49681 gaattcgaaa agactatgat atgacggtca tttctattac ccatgatttg gaagaagtcg
    49741 ccatgagtga tcgcgtattg gtcatgaaaa aaggggaaat tgaatcaact agtagtccag
    49801 gggagctttt ctctcgaaat gatttagatc aaattggatt agacgatcct tttgctaatc
    49861 aattaaaaaa atctttgagc cagaatggct atgatttacc tgaaaattat ttgacagaaa
    49921 gtgagctaga ggataagcta tgggaattgc tctagaaaat gtgaatttta catatcaaga
    49981 aggtactccc ttagcttcag cagctttgtc ggatgtttct ttgacgattg aagatggctc
    50041 ttatacagct ttaattgggc acacaggtag tggtaaatca actattttac aactcttaaa
    50101 tggtttattg gtgccaagtc aagggagtgt gagggttttt gataccttaa tcacctcgac
    50161 ttctaaaaat aaagatattc gtcaaattag aaaacaggtt ggcttggtat ttcagtttgc
    50221 tgaaaatcag atttttgaag aaacggtttt gaaggacgtt gcttttggac cgcaaaattt
    50281 tggagtttct gaagaagatg ctgtgaagac tgcgcgtgag aaactggctc tggttggaat
    50341 tgatgaatca ctttttgatc gtagtccgtt tgagctgtca gggggacaaa tgagacgtgt
    50401 tgccattgca ggcatacttg ccatggagcc agctatatta gtcttagatg agccaacagc
    50461 tggtctagat cctctaggga gaaaagagtt gatgaccctg ttcaaaaaac tccaccagtc
    50521 agggatgacc atcgtcttgg taacgcattt gatggatgat gttgctgaat atgcaaatca
    50581 agtctatgta atggaaaagg gacgtttagt aaaggggggc aaaccaagtg atgtctttca
    50641 agacgttgtt tttatggaag aagttcagtt gggagtacct aaaattacgg ccttttgtaa
    50701 acgattggct gatagaggcg tgtcatttaa acgattaccg attaagatag aggagtttaa
    50761 ggagtcgcta aatggatagt atgattttgg ggcgttatat cccaggggat tcgattgttc
    50821 accgattgga tccacgtagc aaattgcttg ctatgatgct actgattttg attgtgtttt
    50881 gggctaataa ccccttgacg aatctgattc tttttatagc gacagggata tttattgcct
    50941 tgtcaggagt atctctttca ttttttattc agggcttgaa gtctatgttt ttcttgattg
    51001 ccttcacaac tatttttcaa ctatttttca tttctaatgg gaatgtttta tttgagtttt
    51061 cgtttgtgag aatcacggat tatgctttgc aacaagctgg gattattttt tgtcgctttg
    51121 tattgattat tttcttttca actttgttaa ccttaacaac catgccttta agtttggcat
    51181 cagctgtcga agctttatta gcacctttaa agcgtgtgaa agttccagtt catgaaattg
    51241 gattgatgct gtctatgagt ttgcgttttg tcccaacctt gatggatgat acgacgcgga
    51301 ttatgaatgc acagaaagct cgtggagtgg attttggaga aggaagtatc gttcaaaaag
    51361 taaaggcgat gattcccatt ttgattcctc tttttgcgac aagtttaaaa cgtgcagatt
    51421 ccttggctat cgctatggaa gcgcgtggct atcagggtgg aaaaggcaga agtcaatacc
    51481 gacaattgaa atggactcta aaggatacgc tgaccattct tgttattctc gtacttggtt
    51541 gttgtttatt tttcttaaaa tcttagtagc tttcaggaat tgataaaaag ttactgtaac
    51601 agtttttgat ataaaggtag ggatatgaac cgttttaaaa aatcaaaata tgtcattatt
    51661 gtttttgtca ctgttctgct tgtgtcagct ctcttagcga cgacttattc aagtacaatt
    51721 gtgacaaaat taggagatgg aatctcattg gttgatagag ttgtacaaaa accttttcag
    51781 tggtttgatt ctgtcaaatc agatttggct catttgacac gaacatataa tgaaaatgaa
    51841 agtttgaaga aacagcttta ccaattagaa gttaaatcaa atgaggtgga aagtttaaag
    51901 acagaaaatg aacaactgcg ccaattgctt gatatgaagt ctaaattgca agccacaaag
    51961 actttagcag cagatgttat tatgcgttct ccggtatctt ggaagcagga gttgacctta
    52021 gatgcaggta gatcaaaagg tgcttctgag aacatgttag ctattgcaaa tggtggcttg
    52081 attgggagtg tttcaaaagt agaggagaac tctactatag tcaaccttct gacaaatacg
    52141 gaaaatgctg ataagatttc tgttaaaatt caacatggct ctactacaat ttatggaatt
    52201 attattggct atgacaagga aaatgacgtt cttaaaatta gccaattaaa tagtaatagc
    52261 gatattagtg cgggagataa ggtgactact ggtggattag gaaactttaa cgttgctgat
    52321 attcctgttg gtgaagtggt tgccacaacg catagtacag actatttgac acgagaagta
    52381 actgttaaat tgagtgcaga tactcataat gtagatgtga tagaattagt ggggaattca
    52441 taatgagaca gttgaagcga gttggagtat ttttattgct tcctttcttt gttctaattg
    52501 acgcccatat tagccagctt ctgggctcat ttttccccca tgtacatttg gctagtcatt
    52561 ttctttttct atttctctta tttgagacga tagaagtatc agagtatctc tacctagtct
    52621 attgttttgt tataggcttg gtttatgatg tttacttttt ccatctaata gggattacaa
    52681 ctctcttatt tatcttattg ggagccttcc ttcataaatt gaatagtgtt attttgttga
    52741 atcgttggac aagaatgcta gctatgattg tgctgacatt cctgtttgaa atgggtagtt
    52801 atcttttggc ttttatggta gggttgacag tagatagcat gtcgattttt atagtctata
    52861 gcttggtacc gacgatgatt ttaaattttt tatggattac tgtttttcaa tttatttttg
    52921 aaaaatatta tctataagaa cgacatataa atgtaacaaa ggcgtaatat ttattaggcc
    52981 tttttttggt atactagtat tgtctttaaa agaaggagta tctacgtaat atgaagaaaa
    53041 aaatcttagc gtcactttta ttaagtacag taatggtttc tcaagtagct gttttaacaa
    53101 ctgcgcatgc agaaacgact gatgacaaaa ttgctgctca agataataaa attagtaact
    53161 taacagcaca acaacaagaa gcccaaaaac aagttgacca aattcaggag caagtatcag
    53221 ctattcaagc tgagcagtct aacttgcaag ctgaaaatga tagattacaa gcagaatcta
    53281 agaaactcga gggtgagatt acagaacttt ctaaaaacat tgtttctcgt aaccaatcgt
    53341 tggaaaaaca agctcgtagt gctcaaacaa atggagccgt aactagctat atcaatacca
    53401 ttgtaaactc aaaatcaatt acagaagcta tttcacgtgt tgctgcaatg agtgaaatcg
    53461 tatctgcaaa caacaaaatg ttagaacaac aaaaggcaga taaaaaagct atttctgaaa
    53521 aacaagtagc aaataatgat gctatcaata ctgtaattgc taatcaacaa aaattggctg
    53581 atgatgctca agcattgact acgaaacagg cagaactaaa agctgctgaa ttaagtcttg
    53641 ctgctgagaa agcgacagct gaaggggaaa aagcaagtct attagagcaa aaagcagcag
    53701 ctgaggcaga ggctcgtgca gctgcggtag cagaagcagc ttataaagaa aaacgagcta
    53761 gccaacaaca atcagtactt gcttcagcaa acactaactt aacagctcaa gtgcaagcag
    53821 tatctgaatc tgcagcagca cctgtccgtg caaaagttcg tccaacatac agtacaaatg
    53881 cttcaagtta tccaattgga gaatgtacat ggggagtaaa aacattggca ccttgggctg
    53941 gagactactg gggtaatgga gcacagtggg ctacaagtgc agcagcagca ggtttccgta
    54001 caggttcaac acctcaagtt ggagcaattg catgttggaa tgatggtgga tatggtcacg
    54061 tagcggttgt tacagctgtt gaatcaacaa cacgtatcca agtatcagaa tcaaattatg
    54121 caggtaatcg tacaattgga aatcaccgtg gatggttcaa tccaacaaca acttctgaag
    54181 gttttgttac atatatttat gcagattaat ttacagaggg actcgaatag agccctcttt
    54241 tcaggtttta ccgtgacaat ctctattaaa aattatatca aaatagcttg aaaatattgg
    54301 aaaagtatgg tagaatgaaa attgtcgtgt gaacgataat actcattctt gatgaattgt
    54361 gaagcagttg cccttgggtc gttttgcgag ttgaagtcaa gaagaggaaa aaaacaaaaa
    54421 ggagaaatac tcatggcagt aatttcaatg aaacaacttc ttgaggctgg tgtacacttt
    54481 ggtcaccaaa ctcgtcgctg gaatcctaag atggctaagt acatctttac tgaacgtaac
    54541 ggaatccacg ttatcgactt gcaacaaact gtaaaatacg ctgaccaagc atacgacttc
    54601 atgcgtgatg cagcagctaa cgatgcagtt gtattgttcg ttggtactaa gaaacaagca
    54661 gctgatgcag ttgctgaaga agcagtacgt tcaggtcaat acttcatcaa ccaccgttgg
    54721 ttgggtggaa ctcttacaaa ctggggaaca atccaaaaac gtatcgctcg tttgaaagaa
    54781 attaaacgta tggaagaaga tggaactttc gaagttcttc ctaagaaaga agttgcactt
    54841 cttaataaac aacgtgcgcg tcttgaaaaa ttcttgggcg gtatcgaaga tatgcctcgt
    54901 atcccagatg tgatgtacgt agttgaccca cataaagagc aaatcgctgt taaagaagct
    54961 aaaaaattgg gaatcccagt tgtagcgatg gttgacacca atactgatcc agatgatatc
    55021 gatgtaatca tcccagctaa cgatgacgct atccgtgctg ttaaattgat cacagctaaa
    55081 ttggctgacg ctattatcga aggacgtcaa ggtgaggatg cagtagcagt tgaggcagaa
    55141 tttgcagctt cagaaactca agcagattca attgaagaaa tcgttgaagt tgtagaaggt
    55201 gacaacgctt aatttataca aatagtaatt acctaggagg gcggggctta gcccggctct
    55261 cctattttca aaaaatatag gagaattaaa atggcagaaa ttacagctaa acttgtaaaa
    55321 gagttgcgtg aaaaatctgg tgccggtgtt atggacgcta aaaaagcgct tgtagaaaca
    55381 gacggtgaca tcgaaaaagc gattgaattg cttcgtgaaa aaggtatggc taaggcagct
    55441 aagaaagctg accgtgttgc tgcagaaggt ttgactggtg tttatgttaa cggtaatgtt
    55501 gcagcagtta ttgaagtaaa cgctgaaact gacttcgttg caaaaaacgc tcaattcgtt
    55561 gaattggtaa atactacagc taaagtcatt gctgaaggaa aacctgctaa caacgaagaa
    55621 gctcttgctt tgataatgcc ttcaggtgaa actcttgaag ctgcatacgt atctgcaaca
    55681 gcaactatag gagagaaaat ctcattccgt cgctttgcat tgattgaaaa aacagacgca
    55741 caacactttg gagcatacca acataacggt ggacgtatcg gtgttatttc agttgttgaa
    55801 gatggagacg aagcacttgc taaacaattg tcaatgcaca tcgcagcgat gaaaccaaca
    55861 gttctttctt acaaagaatt ggatgagcaa ttcgttaaag atgagttggc acaattgaat
    55921 cacgttatcg accaagacaa cgaaagccgt gcaatggtta ataaaccagc tcttccacac
    55981 ttgaagtatg gatcaaaagc tcaattaact gatgatgtta ttgctcaagc tgaagctgac
    56041 atcaaagctg aattggctgc agaaggcaaa ccagaaaaaa tctgggacaa aattattcca
    56101 ggtaaaatgg atcgcttcat gcttgataac actaaagttg accaagctta cacacttctt
    56161 gcacaagttt acatcatgga tgacagcaag acagttgaag cataccttga atcagttaac
    56221 gcttcggtag ttgagtttgc tcgctttgaa gttggtgaag gtatcgagaa agctgcaaac
    56281 gacttcgaag ctgaagttgc agctacaatg gcagcagcct tgaataacta ataatagaaa
    56341 ggaagcaaat tgcttccttt tttgtatagg gcttagattt ttcctgaaat tgttttttcc
    56401 ccagtctcac tcgattagaa taattaaaac aaaaagccct ataataaggg ctaagtgcat
    56461 ttaggagact atacttaaaa ttcatagtaa gcgcgttcat aacaaggtat ctatcctaat
    56521 tccccaactt ccagtatact agataaaaaa taattatcgg agtaaaggta ttgtactatg
    56581 ataattcaac taagtgattt aggtcaagtt caccttgttt gtggcaagac agatatgagg
    56641 tagggaatag actcattagc ctatgtagtt aaaacccact ttgaattgga ttctttctcc
    56701 ggtcaagtct ttctcttttg tggtgaacgt aaagaccgct ttaaagccct ttactgggat
    56761 ggtcaaggat tttggctact atataaacgc tttgagaacg gaaaactgac ttggctaagt
    56821 acagaaaagg atgtcaaagc tctcgcacct gaacaagtag attggcttat gaagggcttt
    56881 tctatcactc cccaaatata gtggatttaa actagaatag tacacctctg cttctaaaac
    56941 attgttagaa atcgatttga ctatcctgtt cttatttcat tttactataa attcatcaga
    57001 aagtcgtgat ttctattgaa atgaggactt tctttttata ctcatctgtt ttcaaaaagc
    57061 attctagtcc atctccgatt aacgatggac tttatcacct cct
//
LOCUS       DBEJZV010000010        56670 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.10, whole genome shotgun sequence.
ACCESSION   DBEJZV010000010 DBEJZV010000000
VERSION     DBEJZV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 56670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.10"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..795)
                     /locus_tag="ACL3S0_000770"
                     /pseudo
     CDS             complement(1..795)
                     /locus_tag="ACL3S0_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1281..1679)
                     /locus_tag="ACL3S0_000771"
     CDS             complement(1281..1679)
                     /locus_tag="ACL3S0_000771"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311719.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            1807..2040
                     /locus_tag="ACL3S0_000772"
     CDS             1807..2040
                     /locus_tag="ACL3S0_000772"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311720.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHGFEVVDRTDEVS
                     SKHGFEVVDETDEVSNHIYGKATLTWFEEIFEE"
     gene            complement(2097..2579)
                     /gene="greA"
                     /locus_tag="ACL3S0_000773"
     CDS             complement(2097..2579)
                     /gene="greA"
                     /locus_tag="ACL3S0_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGR1311721.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(2650..4305)
                     /gene="mltG"
                     /locus_tag="ACL3S0_000774"
     CDS             complement(2650..4305)
                     /gene="mltG"
                     /locus_tag="ACL3S0_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGR1311722.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVSTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(4386..4880)
                     /locus_tag="ACL3S0_000775"
     CDS             complement(4386..4880)
                     /locus_tag="ACL3S0_000775"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311723.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(4877..5341)
                     /locus_tag="ACL3S0_000776"
     CDS             complement(4877..5341)
                     /locus_tag="ACL3S0_000776"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311724.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(5351..6685)
                     /gene="murC"
                     /locus_tag="ACL3S0_000777"
     CDS             complement(5351..6685)
                     /gene="murC"
                     /locus_tag="ACL3S0_000777"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGR1311725.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(6696..7313)
                     /locus_tag="ACL3S0_000778"
     CDS             complement(6696..7313)
                     /locus_tag="ACL3S0_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR1311726.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(7361..10459)
                     /locus_tag="ACL3S0_000779"
     CDS             complement(7361..10459)
                     /locus_tag="ACL3S0_000779"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR1311727.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINRQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADTNLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKVLPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADSHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(10552..11718)
                     /locus_tag="ACL3S0_000780"
     CDS             complement(10552..11718)
                     /locus_tag="ACL3S0_000780"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGR1311728.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNESKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(11726..12820)
                     /locus_tag="ACL3S0_000781"
     CDS             complement(11726..12820)
                     /locus_tag="ACL3S0_000781"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR1311729.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVFAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(12978..13700)
                     /locus_tag="ACL3S0_000782"
     CDS             complement(12978..13700)
                     /locus_tag="ACL3S0_000782"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311730.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLEQFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEIL
                     IFDESTANLDAYSEYAIISILYSALKEKTVVIIAHRLSTVKDVDCIFFLEERKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            complement(13725..14660)
                     /locus_tag="ACL3S0_000783"
     CDS             complement(13725..14660)
                     /locus_tag="ACL3S0_000783"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1311731.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            complement(14832..16790)
                     /locus_tag="ACL3S0_000784"
     CDS             complement(14832..16790)
                     /locus_tag="ACL3S0_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1311732.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDANNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(16994..18616)
                     /locus_tag="ACL3S0_000785"
     CDS             complement(16994..18616)
                     /locus_tag="ACL3S0_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGR1311733.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            18722..20167
                     /locus_tag="ACL3S0_000786"
     CDS             18722..20167
                     /locus_tag="ACL3S0_000786"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGR1311734.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMVIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(20210..20407)
                     /locus_tag="ACL3S0_000787"
     CDS             complement(20210..20407)
                     /locus_tag="ACL3S0_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR1311735.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(20508..21079)
                     /locus_tag="ACL3S0_000788"
                     /pseudo
     CDS             complement(20508..21079)
                     /locus_tag="ACL3S0_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(21063..21575)
                     /locus_tag="ACL3S0_000789"
     CDS             complement(21063..21575)
                     /locus_tag="ACL3S0_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGR1311736.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLRDSDF"
     gene            complement(21661..22596)
                     /locus_tag="ACL3S0_000790"
     CDS             complement(21661..22596)
                     /locus_tag="ACL3S0_000790"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGR1311737.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(22667..22966)
                     /locus_tag="ACL3S0_000791"
     CDS             complement(22667..22966)
                     /locus_tag="ACL3S0_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGR1311738.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(22956..23705)
                     /locus_tag="ACL3S0_000792"
     CDS             complement(22956..23705)
                     /locus_tag="ACL3S0_000792"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGR1311739.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(23759..24118)
                     /locus_tag="ACL3S0_000793"
     CDS             complement(23759..24118)
                     /locus_tag="ACL3S0_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGR1311740.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(24120..25520)
                     /locus_tag="ACL3S0_000794"
     CDS             complement(24120..25520)
                     /locus_tag="ACL3S0_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGR1311741.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(25815..26054)
                     /gene="rpsR"
                     /locus_tag="ACL3S0_000795"
     CDS             complement(25815..26054)
                     /gene="rpsR"
                     /locus_tag="ACL3S0_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGR1311742.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(26086..26556)
                     /gene="ssbA"
                     /locus_tag="ACL3S0_000796"
     CDS             complement(26086..26556)
                     /gene="ssbA"
                     /locus_tag="ACL3S0_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGR1311743.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LERRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(26568..26858)
                     /gene="rpsF"
                     /locus_tag="ACL3S0_000797"
     CDS             complement(26568..26858)
                     /gene="rpsF"
                     /locus_tag="ACL3S0_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGR1311744.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(27011..28357)
                     /gene="asnS"
                     /locus_tag="ACL3S0_000798"
     CDS             complement(27011..28357)
                     /gene="asnS"
                     /locus_tag="ACL3S0_000798"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGR1311745.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(28373..28738)
                     /locus_tag="ACL3S0_000799"
     CDS             complement(28373..28738)
                     /locus_tag="ACL3S0_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR1311746.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(28731..29918)
                     /locus_tag="ACL3S0_000800"
     CDS             complement(28731..29918)
                     /locus_tag="ACL3S0_000800"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR1311747.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAAVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(29915..30403)
                     /locus_tag="ACL3S0_000801"
     CDS             complement(29915..30403)
                     /locus_tag="ACL3S0_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGR1311748.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            30724..31272
                     /locus_tag="ACL3S0_000802"
     CDS             30724..31272
                     /locus_tag="ACL3S0_000802"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR1311749.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(31550..32278)
                     /gene="yaaA"
                     /locus_tag="ACL3S0_000803"
     CDS             complement(31550..32278)
                     /gene="yaaA"
                     /locus_tag="ACL3S0_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGR1311750.1"
                     /translation="MKILIPTAKEMNTDLPSIEATPLKPESQAVLDALALYSASQLES
                     FYKVSAEKATEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(32357..32521)
                     /locus_tag="ACL3S0_000804"
     CDS             complement(32357..32521)
                     /locus_tag="ACL3S0_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGR1311751.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGIALV
                     LAAVWLGWPK"
     gene            complement(32688..34283)
                     /locus_tag="ACL3S0_000805"
     CDS             complement(32688..34283)
                     /locus_tag="ACL3S0_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311752.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            complement(34295..34705)
                     /locus_tag="ACL3S0_000806"
     CDS             complement(34295..34705)
                     /locus_tag="ACL3S0_000806"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR1311753.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANHDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(34821..35612)
                     /gene="yghU"
                     /locus_tag="ACL3S0_000807"
     CDS             complement(34821..35612)
                     /gene="yghU"
                     /locus_tag="ACL3S0_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGR1311754.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTVGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(35625..38321)
                     /locus_tag="ACL3S0_000808"
     CDS             complement(35625..38321)
                     /locus_tag="ACL3S0_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR1311755.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38625..39809
                     /gene="mntE"
                     /locus_tag="ACL3S0_000809"
     CDS             38625..39809
                     /gene="mntE"
                     /locus_tag="ACL3S0_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGR1311756.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(39952..41823)
                     /locus_tag="ACL3S0_000810"
     CDS             complement(39952..41823)
                     /locus_tag="ACL3S0_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR1311757.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQVKDRIGIVGDNGVGKSTLLNLIAGSLESTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(41820..43019)
                     /locus_tag="ACL3S0_000811"
     CDS             complement(41820..43019)
                     /locus_tag="ACL3S0_000811"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGR1311758.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNLQAI
                     TEKYQSLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            complement(43016..43783)
                     /gene="dapB"
                     /locus_tag="ACL3S0_000812"
     CDS             complement(43016..43783)
                     /gene="dapB"
                     /locus_tag="ACL3S0_000812"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGR1311759.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWIDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(44049..44897)
                     /locus_tag="ACL3S0_000813"
     CDS             complement(44049..44897)
                     /locus_tag="ACL3S0_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR1311760.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(44899..45273)
                     /locus_tag="ACL3S0_000814"
     CDS             complement(44899..45273)
                     /locus_tag="ACL3S0_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGR1311761.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(45347..46699)
                     /gene="glmM"
                     /locus_tag="ACL3S0_000815"
     CDS             complement(45347..46699)
                     /gene="glmM"
                     /locus_tag="ACL3S0_000815"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGR1311762.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSVIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(46723..47502)
                     /locus_tag="ACL3S0_000816"
     CDS             complement(46723..47502)
                     /locus_tag="ACL3S0_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGR1311763.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(47489..48346)
                     /gene="cdaA"
                     /locus_tag="ACL3S0_000817"
     CDS             complement(47489..48346)
                     /gene="cdaA"
                     /locus_tag="ACL3S0_000817"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGR1311764.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            48482..49450
                     /locus_tag="ACL3S0_000818"
     CDS             48482..49450
                     /locus_tag="ACL3S0_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR1311765.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(49703..50659)
                     /locus_tag="ACL3S0_000819"
     CDS             complement(49703..50659)
                     /locus_tag="ACL3S0_000819"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGR1311766.1"
                     /translation="MDIDTSRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGFYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYWFDNSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGSMADKPEFTVEPDGLITVK"
     gene            complement(50659..50994)
                     /locus_tag="ACL3S0_000820"
     CDS             complement(50659..50994)
                     /locus_tag="ACL3S0_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HGR1311767.1"
                     /translation="MQQITEIITNGAISILVVLAGVVVRAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            complement(50998..51297)
                     /locus_tag="ACL3S0_000821"
     CDS             complement(50998..51297)
                     /locus_tag="ACL3S0_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311768.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            complement(51307..51657)
                     /locus_tag="ACL3S0_000822"
     CDS             complement(51307..51657)
                     /locus_tag="ACL3S0_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311769.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVKPKE"
     gene            complement(51660..51863)
                     /locus_tag="ACL3S0_000823"
     CDS             complement(51660..51863)
                     /locus_tag="ACL3S0_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311770.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(51844..51960)
                     /locus_tag="ACL3S0_000824"
                     /pseudo
     CDS             complement(51844..51960)
                     /locus_tag="ACL3S0_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
     gene            complement(51957..>56670)
                     /locus_tag="ACL3S0_000825"
     CDS             complement(51957..>56670)
                     /locus_tag="ACL3S0_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0098024 - virus tail, fiber [Evidence
                     IEA];
                     GO_process: GO:0019062 - virion attachment to host cell
                     [Evidence IEA];
                     GO_process: GO:0046718 - symbiont entry into host cell
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HGR1311771.1"
                     /translation="KSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIAS
                     VQVGGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKTIDVSDSPATGFDKAIRLTSSN
                     ARDQIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQVNDNSGISPIFTLKDENW
                     TKLSFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQLEDGSLATSSKEAPEDIEGQI
                     STVESTFKQRANSLEAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQ
                     KLSQAEFEVRAGSIHQEILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLF
                     KQDISKTGIWTTSTYTAAIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGK
                     VIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWT
                     NESKQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRA
                     NSLDAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRA
                     GSIRQEILNATKDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPEN
                     HVTGQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFK
                     HYLFRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEG
                     ATSGTAWVTGIKVEIGSVATDWSPAPEDADGLITEAKATFERTAQGLRTDLSAIQEYV
                     NKNGQRQEALQRYTREESTRQATAVRELVNRDFVGKVTYQEDVKGINQRIEAVKTSAN
                     KDIASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGATTQISNIS
                     NRINSNKQGTDNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLA
                     RKVETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLI
                     KNSDFKNATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNT
                     DYVLNFRGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNS
                     GEMDNAYIRFDNNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDVVADANKKLEATQT
                     KMTLLTGSWAVQNINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVD
                     KLKTGNFEAGSVTTTILEAEAVTAEKLKVDNALIKKLTANDAFIDQLTSKRIFSTKVE
                     SVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGHGVRTAFWANW
                     GNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGI
                     ELGSKDVLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKENITDTAVKALDK
                     INRLRMVAFDFIESKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLI
                     KAIQELNQKIEKMEKTIA"
BASE COUNT        16061 a        12902 c        10641 g        17066 t
ORIGIN      
        1 ttctttggga gtcattttct tggttccctt aggtaaccat ctacgaatga gcctgttgtg
       61 attctcatta gttccccttt cccaagaggc ataggggtgc gcataataga tgtgctcctc
      121 agaaaacaca tcaaacaagc gattgaattc cgttccatta tctgccgtga tggaaagaat
      181 cttgtgttgt tttaagatga gttttagagc ctgattgacc acctcagcac ttttatttgg
      241 aatcaatcgg atgatctgat gtctactctt tcgatccgtc aagacaagca agcagtagtt
      301 tttcgctctc gtaagtagaa ccgtatcaat ctcataatgc ccattctcca aacgaagatt
      361 gatagcttca ggccgctgtt cgatggattg accagcaggt ttaaagttgg tgctggcctg
      421 tttcttaagc gcttttcctt ttctagggta aagcagatcc tgcttgcttt accccaattt
      481 tccatgatga atccaatagt aaatggttga aattcccacg ttaacccctt tagccataac
      541 catcatttca ggcaaaaatt tttggttatg atagtggaga atcttttcct ttagttcctt
      601 ggtcacgctt gatctcttga ccgagtgctt gcgattattt tcataagact gttgagcata
      661 gtcggcagaa taaacctctt tgaagcgccc ttttccaaga cattttcgga ctgtcctacg
      721 cttgatttta gtgtggatag tttgaggagc ttttccaagc agagaggcaa tttctctatt
      781 tgatttccct ttgttcgcct tttgtagtat aatggttttg catctctgtg cctttcttgt
      841 gtttgtggtt gaacaacaag tataacacag aggtgttttc ttatgcctac aagagctttc
      901 attatttcca ttttctttcg gatttcactc tattctgaaa aacttgtgta tatttactga
      961 agctagcaag tcttacctgt aaatttaatg aaagcaacac aaaatccgag aggggaatct
     1021 cggattaatg tcaatttaaa aagatagaga gtttttagtt taaataaatt gttttaaaat
     1081 atcaacaaca tcacttcttt tcttaacctg ataagccttg attcctaatt ttggagctac
     1141 gattatattg tcctcaatat cgtctagaaa gacacaattt ctaggttata actggtattt
     1201 atcgatagtt actcatatac atcagtccac ctccatactt atgtgcgagc ctctctttgt
     1261 attatacctc catactcacc ttacagattc ttttggtaat aatatctttg cctaatgtag
     1321 agatagtctt gcaaagaaaa aacttccttg tagccatgtt tctgataaaa gtccggtgcc
     1381 tggaactgat aagtattgac aaaggcaaaa caacaatttc gattcttagc ttcactttct
     1441 gcctgttgca atagttttga accgattcct tgccctcgca gttcctcttt tacaaacaaa
     1501 tactcgattt ctagccaatt tccaaaagtc tctgctatca aacccgcaag gagattgccc
     1561 ttttcatctt cgacataaag attaagtggc tcactttcag cctcttccct ttttgaacgg
     1621 ttataaacac gaatcagatt ccctatttct tgcgatttat gtgattcctt attttccaat
     1681 ctaaagtata atgaaatgaa ataaaacatg cgcaaatcga ttaaggaatt taatctaatt
     1741 tctaataatg tcttagaaat caaagtttac tattttaact tcaatgcact atacatctaa
     1801 tactcaatga aaatcaaaga gcaaactagg aaactagccg caggttgctc aaaacactgt
     1861 tttgaggttg tagatagaac tgacgaagtc agctcaaaac atggttttga ggttgtagat
     1921 agaactgacg aagtcagctc aaaacatggt tttgaggttg tagatgaaac tgacgaagtc
     1981 agtaaccata tatacggcaa ggcgacgctg acgtggtttg aagagatttt cgaagagtag
     2041 caaaatggaa aaaggagtga gtgaagcaca tcgcctcccc actccttttt ctgtttttag
     2101 gctgtttttt caaccttcaa gatttttaca tcatagctac caacaggcgt ttcaattgtt
     2161 gctgtgtcac ctgttttctt gccaatcaag gcctgcccaa ttgggctttc atttgaaacc
     2221 ttacctgcaa aggcatccgc accagctgaa cctacgataa tataaacttc ttcttcgtcc
     2281 tcgccaattt cttggatggt gactgtttta ccaatcgcta cttcgtcctg ggcaactgcg
     2341 tcgctattga cgatttcagc atagcggatt tttgtttcta agctagagat ttgtccttcg
     2401 acaaaggctt gttcatcctt agctgcttcg tactcactgt tttctgaaag atcaccgtat
     2461 gaacgggcaa tcttaatgcg ttctaccact tctggtcgac gaaccaattt caattcttct
     2521 aattcttttt caagtttctc cttttcctca agggtcatag gatatgtttt ttctgccatt
     2581 tttctcaact ttcttctgat aatattttct aaagaaaatt atgtgacgta tcacataatt
     2641 ttagtttgtt tagtttaatt tgctgttgac atgttcagcg acattgcggt cgtggtcttc
     2701 ttgattgtta gcatagtaga ccttgccttc tgtgacatct gctacaaagt agaggttatc
     2761 gctcttagtt tgattgatgc ttgactcaat cgcatccaga cttggactat cgactggacc
     2821 aggcatgaga cctacatttt tataaacatt ataaggtgaa tcaatgttgg tatcaatcgc
     2881 aacatcctca gctagactga tattttgccc cagttttcct tgggcataca agattgcaat
     2941 attactttga agtggcatat cacgatttaa acgattgtag aatacacctg caatgagctt
     3001 acgatcttct gtcttggcac cttctttttc gaccaaggaa gcaatggtca acaactcatt
     3061 gacagtcaaa tttttagatt tgatagtact atagtaagga gataggttct tatccatagc
     3121 agctaacatc tcatcaatca agctctcaat agttgtgctt tccttgatag agtatgtagc
     3181 tgggaaaagg tatccttcca aacgataacg cgcaccgctg tcttttacag gcaaactttc
     3241 cagtaaagta ggatatttcg ctactgcttg actgataaac gtctcatctt gaactttagc
     3301 caagaaagcc tccgctgtca aagactcttt gaagtcacct tgcaattgac ccacagcttg
     3361 agcaatctga tccaaggtat aaccttctgg aattgtcaaa gtcgcaagta caggttcttg
     3421 cggttcatct gttccacctt tttgcaactc tttgagtaag tcttctgtac tcatactctt
     3481 ttgcaaattg tagtaacctg ctttcaagtc ggtataattt ttatacttgg cataaaaact
     3541 aaaaatcaga ccatgcttta ccaaaccagc tttttcaagc gtcgtaccga tttcttgaac
     3601 gtttgaacct tctggaattc caaccgtcac atatttctta gaattagcat cgataggtaa
     3661 caaagaatct agcacgtact ggtaaccaaa gtaaccacct gctgagagca aggcaaggaa
     3721 tacaaggaat gaaatcacaa aagctttcac atgtgacttc ttctctttct taggattaac
     3781 gggttttgct ccttctctac ggctacgacg tgatgtatcg ctgatgatat ccactgtttc
     3841 tgtagcaggc gtaggtgttt ctggacctgc ttgttctgct tttttctctg ccgtcgtata
     3901 ggaaacagct acccttgttg gggtttcatt gtattctctt tcaagtttct taggtctaac
     3961 aggacctgga cctggtcttg atccactttc ttccgctgga gaagaaggta catcttgact
     4021 tggatgactt ggaacaccag gagtttctct ttgaatctca tctgctggag aagctggtac
     4081 accttgactt gggtgagtag acacggtagg agcttttctc ataatctcct ctaccgttga
     4141 caaggaatca gccatgagtt cttcagctga aggttcattt gcaggagtgc gaactactgc
     4201 ctcatcttct ttcagaactt catcatagcc ttttactttt tctaaatctc tcagaatctg
     4261 ctctttaaag cttaatttct cttcttctct tgacttttca ctcaaaagtt tttcctcctt
     4321 gttgataatc cataatatta tatcttaaaa gtccaaaaaa agcaatctat gatacttttc
     4381 ctaacttatt ttttcatttc ccagaccata tcataccatg tttcccctgc aaaggttgac
     4441 tgggactggc cttcgttgac aaatccatgt ttttcatagt aggcgatgag atagtcatga
     4501 caggttagat taatgccatc tctctcatct tcaagagcaa cttctttcaa ggctgtcagc
     4561 aatttctgac ccagtccgag tccctgtgcc tccttggcaa tagacagaca ggtcacagag
     4621 atataaccac caggctcatg actatagtct tttatttctt ctgtaaaaga ctggtcttgc
     4681 agatggcggt gcaggccaac tggtccttcg atataaccca tgattcttcc ttctttttca
     4741 gcaaccagaa aagaggtctg aatttctctc aaatgtgctt caaagacaga aggaggaatg
     4801 gcttcttcga ccgaaaaatt ttcaaattca agttcaacaa tccgatccaa atcttctaat
     4861 cttgcttgtc tgattttcat tgttcctcca gataaaaggg attaaaccaa atcatactat
     4921 agccctggct agttgcatag agcaaagttg cttcttcatc aacaaaaccg ttcatttcaa
     4981 aataggaaag cagctcatca ggactctcca aacgaatccc tttgtaatcc agctcaactg
     5041 ccacctcttt caaggctgca agaagaagtg ttcccaagcc ctgtctctga tggtcagact
     5101 cgatgactaa agaatgtact tttagatatt gcggattgtc tgactgggga cttgataaaa
     5161 tatagcctaa aagttgattt tcatccctag ctagaagaaa ggtatccgca cacttacgga
     5221 tactttcttc taaaatatgg gaaagttgct gcttttcagc tggaaaagac gaggtctgaa
     5281 gtgcccctat ctcaggcaaa tcagacttgc ttgcctgaat gatcttaatt ggaatttcca
     5341 tgggaacatc ctattgaaca ttgcttgtca agttagacaa gagacgctca aatgagtatt
     5401 cataggtttg gatgtctcct gctcccataa agacgtaaac agcattgtca tggtctagga
     5461 gcggagaaac attttcaaca gtaatcactt ggtgtttttt gttgattttg ttggctaggt
     5521 cttctacctt aacgtcacca tgatctactt cacgagccga gccataaatt tgcgctagat
     5581 aaacagcatc tgcttggttt aaagcatggg caaagtcgtc caacaaggca atggttcttg
     5641 taaaggtatg cggttgaaag actgctacaa tttccttgct tgggtatttc tgacgagccg
     5701 catccaaggt cgcaataatt tctgttggat ggtgggcaaa gtcatcgata atcactgtat
     5761 cattgacaat tttctcagtg aaacgacgtt taacaccggc aaatgttttc aagtgctcac
     5821 gcaccaagtt caaatcaaat cctgctgtgt aaagaagacc aataacggct gtcgcattca
     5881 tgatattgtg acgaccaaag gttggaatgt ggaattgccc caagttttgt ccacggaaat
     5941 gaacggtgaa ggttgaacca gttattgaac gaagaagatc actagctaca aagtcattgc
     6001 cttcaacttc aaaaccataa taataaattg gtgcatcaga cgtaatctta cgcaattcag
     6061 catcttcacc atagacaaaa agacccttgg tgatttgttt ggcatagtcg ttaaaggcat
     6121 taaaaacatc ctcgagactt gtgaaataat ctggatggtc aaagtcaatg ttggtgataa
     6181 tagagtattc tgggtggtaa ggcatgaagt gacgctcata ttcgtcagat tcaaagacaa
     6241 aatatttggc attggccgaa ccacgacctg tcccatctcc aatcaagaag ctggtatctg
     6301 taatgtgaga caagacatga gacaacatac ctgtcgttga agtttttcca tgtgctcctg
     6361 ctactcccat gctaacaaag tcacgcataa agctacctag aaactcatgg taacgtttgt
     6421 agctgatacc attttggtcc gcataggcaa tttcgacgtt gttatctgga cgaaaggcat
     6481 ttccagcgat aatttccata tcaccgtcta gattcttttc atcaaaagga agaatggtaa
     6541 ttcctgcctg ctcaagaccg cgttgggtaa agtagtactt ttcaacatct gatccctgaa
     6601 ccttgtgccc catctggtgc aacatcaagg ccaaggcact catccctgat cccttaattc
     6661 cgataaaatg atatgtcttt gacatgtttt ctcccctatt ctgtcattct ggtcagattc
     6721 aactcttggg caacccgacg ttcttgttct gtttgtttac tttttttatt gtagatttgg
     6781 ctcttcttta gaaaatcata attgtttttc tttggagcag gtgctgacac ttcttcattc
     6841 ttggtaggga tagaatgaac ttcttccgcc aagatataat gagactgggt caatttttgg
     6901 ctatatttga caaattcacc aggattttcc ttttggaaag gagttgtcgg ttgattgccc
     6961 tgtctaacta gactgggctg agaatgacgt ctcgcaaggc tgaaatcctg agttaggtag
     7021 ttagcagagc gtttcttttt caagtccgca cgcgcttctt cacgcgccac ctccgcatag
     7081 ctctttcctt cttttttaac ccctaaagga gcctttttag gtttttcgac ttgcttttca
     7141 atcggtttta ctggtttttc ttcagcaata ggagcccatt ctaaataatt tttatctcga
     7201 tactcaccct tgatattact gatcagatca gactcatcat agagattcat gactggcatt
     7261 tcagtcaaca tgacctcgtc atctgacacc aatggaaatc gttcttgttt cattttctat
     7321 ttcctttcaa cacttcatta tagcgtattg tcttgatttt tcaagtgctg gcttcagaaa
     7381 ttcccaaaat ttctctaatt tctgctaggg tcagactacc acgtgactct gtgccgtcca
     7441 atacttgtga caccagatgt ttcttttgtt cttggagttc ctgaattttt tcttcaatgg
     7501 ttcccttggt caccaagcga tagacctcaa ccgtttcttc ctgacccatc cgatgggcac
     7561 ggccaatggc ttgcgcttcc accgcaggat tccaccaaag gtcaaccaag atcactgtat
     7621 ctgcacctgt caggttcaga ccgaccccac cagccttgag ggaaatcaga aaggcatctc
     7681 tttctccttg gttaaaggcc ttggtcatgt cttgtctttc cttggctggg gttgaacccg
     7741 taattttaaa ggaagtcagg cccaagtctg gcagttcttg ttcaattttt tccaacattc
     7801 ccttgaactg agagaaaatc aagacacggt gtccgccgtc tgccacctgt accagtaggt
     7861 ctcggagact atctagtttg ccgctggctc cctgataatc ttccataaac agggcaggag
     7921 tgtcacatat ttgacgcaag cgcatcaaac cagataaaat ttccacacga cttcgctgaa
     7981 attcctgttc tgacacttga gccagatggt ctcgcatctg ttgtaactgg gcaaggtaaa
     8041 tagccttttg ctggtcttcc agttcatttt tataaaccac ctcaatcaag tctggcaatt
     8101 cagtcagaac ttcttctttc ttgcgtcgca tcacgaaagg cttgataaac tgagccactc
     8161 gctctgctgg caatttcata aattctttct tgcttggcaa aagtccgggc atgacgattt
     8221 ggaaaataga ccacaactca cccagatggt tttcaatcgg agttcctgac aaggcaaaga
     8281 ccgacggcac cacaaattgt ctcaaggtct gggcaatctt ggtctgggca tttttcatga
     8341 cctgagcttc atctaagaaa aggaagtcaa aggccatccc ctgataaagc tcactgtcct
     8401 gacggaaggt ggcatagcta gtcacataga tttgatggct atcggcaaga atctcctcac
     8461 gacttgcttt caaaccatga acaacagcca catccaactg tggggcaaat ttctgaaact
     8521 catccgccca gttgtaaatc aaacccgacg gagcgagaat caagactcga ctttcttttg
     8581 tcacttgact agtcaaaaaa gcaatggtct gaagggtttt cccaagtccc atatcatcag
     8641 ccaaaatccc accaaaacca taatgatgga gcatctgcaa ccagccaatt cccttttcct
     8701 gataatctcg caagtcagcc ttgacctgag ttgcttgcaa aggaaagtcc tctggatgcg
     8761 tcaaatcctg ggccagattc tggaattctt gtgaaaaaga aacacggtct cgcccttcaa
     8821 agagatgagc taaactgtag gccaaggatt tccgagcctg caaggtccca tcttttaatt
     8881 caaattgccc cagttcctgt agattttggc gaattttctt ggtttcttca tcgaaaaagt
     8941 aaacttgatt agacgaatca atataaaaat cctgattggc aaccaaggcc tgcatggctt
     9001 ggtcgatttc ctcctgggca atattttgaa aatcaaactg gatttccaag agacctccct
     9061 tggaggcaat ctgcacctga ggactcgcta ggctataaag ctcttctagt ttatctgata
     9121 ggtcaacatg cccgagtttt tcaaagactg gaatgatatc atgaaaaaaa tgatagacag
     9181 actccgcttt taaggcctga cgccaagatt gaaaatcggc ttcaaagccc gcagccaaac
     9241 agacttggaa aattctttct tctaagtccg cgtcacttga aaatggtaat tcttctagct
     9301 cttgtcggct agatacctgt ctatttccat aatcaaactg aatttctaaa cgaatccgat
     9361 tatcttcttc cctgtcaaag taaaaagagg gcgcaaaagt tttgatttgt agacgttctg
     9421 gagctgaaac ggtgcccatc tggataaaaa gagtcagaca ggaggccaat ttgtctcgat
     9481 cactgctatc aaattgcagg tatttctttc cttgttgacc cacaggtaac actttaattt
     9541 ccttgagaag acgcatctgc tggtctgtta aaaaataaac ctgaccttta tggaaaagta
     9601 ctgctccctg ataaaagaca ttgaccctag gactctcact gatttccatt tcaaaatagt
     9661 ccgagtattc tgttactgta aaggcaaata gattggtatc agcatgcata tcctgaaaaa
     9721 gcagggtttg gtagctatcc acttgatggt caaattgaaa atggggcaag gccatcagta
     9781 aattcacacc ctgctcaaaa aaggtcagag ggaaaaagag gtgccgacct tggttttgga
     9841 aaaagaggtc tggaaccagc ccttcctccg ttagtccgtg caagaaagtc aaaagttctt
     9901 ggctggcatc atcaaaggct tcccaagaaa gagactcctc ataaatcttg ccaatcatat
     9961 acgactttct ctgctcgaca atccttaaaa aaagtggaat atcccgaatg acatagtatt
    10021 tttgtctatt gatttggccg attctcagag tccacaagat atgattggtt cctgcttcca
    10081 cctgacccac agctgataac tcataggcgc attctgattt cggagataaa attcgattca
    10141 aaaacttgcc acccaaggtc accttggttt caacggcctc tttttcttca tgaccttctt
    10201 ccagactcca caagatttcc tgaccacgct catcattttt cagaaaatgc tctagcgctg
    10261 ccaaatgcac acagtagccc ctcttttgaa aagaatcaca ggcacaaaaa accaaatcat
    10321 cctctaaact atagcgcagt tcttcttctg caacgcgagc gtagagccga ttgttctttt
    10381 ccttgatgat atcaacctta ccagtttcat aaagggcaac accttcgata cgaactttcc
    10441 ccggaatcaa tttagccata ttttcacctt taccttatct ttttattata ccatattttc
    10501 gcctatgaaa atagccttct aggaagactt ttctcctaga agactggatt tttaacgttt
    10561 ggcaaaagta gccacaatcc gctgacagac ttcctgcaac agagatttgg gcatagctat
    10621 attgatgcgg gcatggagac ttccttcctc tccaaaatcc aaaccacggt tgaggataac
    10681 cttggattca tttctcaaca actcttgcaa tgtttcatca gtcaggtcat aggctgaaaa
    10741 gtcaagccaa atcaagtagg taccttgcgg tttcatgacc ttgattttag tctcttttcc
    10801 aaatagatct accacataat tgatgtggtc ttcaaagact tgcttgagtt cctctagcca
    10861 atctttaccg tatcgatagg cagcttctgt cgccaaataa cccaagcctg aaatttcatg
    10921 ctgattattg gccaacaggc gtttctggaa agccagtctc aacttaggat tttcaatgac
    10981 tgcataggaa ttttttgttc cagcaatatt aaatgtttta gtggcactgc tcaagacgat
    11041 agcaaaattt ttgaaggcag gattgatggt attgaaagac tggtgtttgt gaccaaagag
    11101 ggtcaaatct tggtgaatct catccgaaac taacaaaaca ccgtgttttt ggcagagttg
    11161 gccaatcttc tccaacactt ctttttccca aacacgtcca ccaggattgt gaggattgca
    11221 aagaatatag agtttaacct cctcttccac caaatccttt tcaagttggt caaagtcaat
    11281 ctcaaacaga ccatcctttt ccactaagga attagtaatc aatctacgat tattcaactt
    11341 gacactgcga gcaaagggtg ggtagacagg cgtgttaatt aaaaccgcct cgccttcttt
    11401 tgtaaaggtt tgaatagctg ttgagatggc tggtaccaca ccctcgataa agacaagagc
    11461 ctctttgtca aagttgtaac cgtattgtgt agcttcccac ttttgaactt ccttaattaa
    11521 gtcttcactg gcataggtat aaccataaac cagttggtct gcgtaagttt gcacggcttg
    11581 gcggatttca ggcaagacca caaagtccat atccgctatc caagctggta gaacttcact
    11641 atccgtttct gtttctttcc atttataggt atggtgccct aaacggttgg gcaggcttgt
    11701 aaaatcatat tttcccatct ttgtcttatc cttctaaggc ttggcgcaaa tctgcaatca
    11761 aatctctagc atcctcaatc ccaatagaca aacgcaagag gtcatctgtc aaaccataag
    11821 aatggcgtac ttctgctgga atatcagcat gagtttgagt cgttggataa gtaataagac
    11881 tttccactcc gcccaaactt tccgcaaaag agaagacctt gagactgttc aaaatatgag
    11941 gaatgcgtgt ttcatcggct actttaaagg aaatcatgcc tccacgacca gtgtagagaa
    12001 cttccttaac tgctggagaa tccttcaaaa aggcaaccac ttcttgggcg ttagctgttg
    12061 agcgctccat acgaagagac aaggtcttga gaccacgaag caactggtag ctgtcaaatg
    12121 gagacaagac tgcccctgtt gtattaagat tgtaaaaaag cttctcgtat agttctaaac
    12181 tattggtcac aaccactcca gccaagacat cattgtggcc tgctagatac ttggttgctg
    12241 aatggagaac gatatctgct ccatcttcaa tcggacgttg gtagataggg ctatagaagg
    12301 tattgtccac caccactttg gcacccttag catgagccaa ttttgctagt ttttcgatat
    12361 caaattccaa catcaaggga ttggttgggg tttcgatata gagaacatcc acatcctttt
    12421 ctaactcggc aatcaactct tcttctgtat tggcataggt aaaatggaaa cgaccttcct
    12481 gctccacttg gttaaaccag cgaaaagaac caccgtaaag atcacgcact gccaagacct
    12541 tacttcctac tggaaagacg ctaaaggcca gtacaatagc tgacatccct gagctagtcg
    12601 ctagggcata gtctgctgac tcaatagccg caaagacttc ctcagcctta ctacgagttg
    12661 gatttttagt gcgcgtatag tcaaacccag tagatcgacc aaactctgga tgctgatagg
    12721 tcgttgaaaa atgaagcggt gtcaccaatg cacctgtcgc ttcatctgac ttaatacccg
    12781 cctgggccaa aattgtgtta atgtgtaatt ccttgctcat acaatacctc caaatctata
    12841 gtaactattg taccacttat tttcatcaac tcattttctt cttttcaaga gctagttata
    12901 gtttcaaact atataaaaag ggagtttttc ctgctccctt taatagacta taaaatggtg
    12961 aatctcaaaa gacaccttca ctctatcatt tgctcctgca caaaacgagc ataacgctca
    13021 tgattttcca gtagttcctt atgagttcct gagccagtga ttttcctctc ctctaagaag
    13081 aaaatacaat ccacatcttt taccgttgac aaacgatgcg ctataatcac aaccgtcttc
    13141 tcctttaatg cagaatagag gatactgata atcgcatact cagaatacgc atcaagatta
    13201 gcagtggatt catcaaatat aagaatttca gcatctttta agtaggttct agctatttga
    13261 agtctttggc tttgcccccc tgacaagaat cgtccgcgtt caccaacttc agtatctagt
    13321 ccctctttca tggagcgaat ctcatcacct agtgatacta agtctagcac tttcatcaat
    13381 tcatcatcag ttactaagcg attcaaaccg agacaaagat tgtcacgaat actgccagat
    13441 aagactgcat tattttgtga aacccaagcg attttacttc tccattcttt taagttaaaa
    13501 tcatatatac ttgattgctc cattagaata tctcctgaaa gcggtttata aaactgctct
    13561 aacaaacgca caatcgttga ttttcctgat ccagatggtc caacaaaagc aattttttgc
    13621 cccttgaaaa ttgaacaagt aatatccttt aagacaggtc gattttcatc ataaccaaaa
    13681 tagacatggt taaaattcaa cccttgtcct gataccgatt ttcctcactc aaatttttct
    13741 ttaggaactg caagcaagtt ctccagtgca actgaagatc ccttgctcct agaataaaca
    13801 gttacaaaat tagctatatt actaatagga ttaagtaatt gaaagaggta aatcaaaaac
    13861 gaaaccaagg ttcccacaga tatatatcct gcgctgaccc gataaccccc ataggttagc
    13921 atcacagcta tagtcgcaaa gataaataag agagcaaacg gggtctcaaa agaagtaacc
    13981 ctatctgatt tcagtgaatt gttttgtacc ctttcaatac aattatccaa aacatcctgt
    14041 acacttttct ctgcttggtt agtcttaatt aattcatgtt cttgaatctt ttcagtcaat
    14101 tgccctgtta aaaatccgat ttcctcctgt aaacgacgac tatacttttc actgatattg
    14161 gaaaggggca agataataaa catcatacaa ggaagagtga tgaataaaag tagagaaaga
    14221 ttccaatcaa gactaaataa gactacaatg gaaccaagta ccataactaa actcagaata
    14281 atatttggga aagtcgtaat taaaaactca cgaatgacac tcgtgtcatt gacaatggca
    14341 gaagtcaact ccccactttg gctcttatca aagaaggatt tctctgcata aatcaacccc
    14401 tctatcactt ttttcctgat ttttgctatc tttttttcac ccgattgact aaacagatag
    14461 taaccaatag aagaaaacaa ggcttgacca ataaaaatca aaaacgattg aaatactttg
    14521 gaacctatat tttcaataga actcccatct attaaaccct ttaagataag gggaagcaac
    14581 aaagcaagta gactagacag aacaagtaag aaactcccca taatcacctt agtatctact
    14641 cttaataatt ttaatttcat aaatactcct tataatattt caacggataa agtcgggaat
    14701 aactcaattt gaggataaaa tctaataaat cttcctataa caaaacgcat aacatctagg
    14761 attttatata cctgatatta tgcgttttta agcacaaaga cttcttacac aaacttatct
    14821 acaattagat tttatttgac atgttttgcc aattcttctt gggctttttt attggattct
    14881 tctttttctt tcaaccattt ttctctggct tttgcatatt cgtctgttgt gacaatctta
    14941 tcttgtactt tgaggtattt atatgattca accccttttg taccggttaa accataggca
    15001 gcagcaaatg gtacggttct tctcaatgat ggtgttcccc cacgcgaaac acttggaaga
    15061 actaaagaac tatcaatcaa ccaagcttga atatcagcat atttctcata acgtttggct
    15121 ggatcttgct ctttattagc ttcttccaac atttgagtat agacatccag tccaactgcc
    15181 ttagccttgt cattggcctc accaggctct agtccaagat tttgcagaaa tcctccacta
    15241 ttagtattaa aaatatcgag ataggttgac gggtcttgat aatcaggtcc ccaaccgcca
    15301 tgatataaat catagtcttt ctgagcagct gtttgagcaa agtagcctga actgtcaaac
    15361 tcatctgatg ttaattgctg aatgtcaatc actacattat cagaacctaa aacagattca
    15421 attgattgtt tgatagaact aactccttgt atgcctactt tatctgttac ttccacagtc
    15481 ttatccaagt ggattgggaa ttgaacaccc tttgcttcga gttctttctt agcttccgca
    15541 aacttagcct tggctttctc aggattgtag taagggtctt gaccatccgc aaagttgata
    15601 ccttgccatt ccttaccata gttgaccatc ttagaggcta caacttcacc aaagtctttt
    15661 cccttgatac tgacaaagtt tggaggaacc actaggttac gcaaaatctt tgttgcacct
    15721 tctttccctt cagactgagc cccataagat gttctgtcaa aagcaaaatt gatagcctga
    15781 cggaagtttt tattgagaac tgcttcctgg gtcgatttct tttcaatgtc acttgtttta
    15841 gaagtataat tgtaagactt cctatctagg ttaaaattaa agaaatatga agttgaattt
    15901 tgcatactat agatgatatt gtttttgtat ttttctttaa tcccttcata gctggagctg
    15961 ttaggaaaaa gacgagccgt agtataagca ccagctgtaa aattacgttc cagtgattct
    16021 tggtcgctac catcatagta ggtcaatttc acatcgtcta caaagacatt attagcatcc
    16081 cagtaattag ggtttttctt atattcaata gcagattttg agacaagtgc tttcatcaag
    16141 aaaggtccat tgtacaaaat actagatgga tccgccttcc caaaatcatc cccttttgat
    16201 ttcaggaaat ctgcattaac aggaaaaagt atcgttgcaa gtgtttttga attccagtaa
    16261 agttctggtt taaccaaagt atattgaacc gtttggtcat caagtgcctt gacaccgaca
    16321 gttgaaaagt cgcttgtttt accagtgata tagtcatcca aaccagcaac agagtcctgc
    16381 actagataca aggcttctga ttttttatca gctgcatatt gcaaacctgt cacaaaatcc
    16441 tgggcagtta caggcgcata ttcttctccc tcagaagtaa accacttggc atccttacga
    16501 agtttgtagg tataggtcaa accgtcctga gaaacagtcc aatcctctgc taatgatgga
    16561 ataatattcc catattggtc attttctaat aacccgtcta ccaaatttgc aacaatatcg
    16621 gatgttgctg cgcggttttc tgctagatag ttcaagctag atggatcact tgaataaaca
    16681 tagttgtagg tttttgacgc cgtgctagaa tttccacacg cgctcaataa aactcctgta
    16741 cccaggacaa gacctgccaa ggttagatat ttgctcttag actttttcat ttccagaacc
    16801 tcctgcttta aatatttgtt ttattataca actcttggtt tgtttagtca attgtttttt
    16861 ccaaaaaatc aaaaaaaacc tcattttcta tttttgaaag ataattttag ctatttttac
    16921 gctaaaaaag gaataagttt caagttctcc taaaagattg ttcaacttat tccttttatt
    16981 tataaatgct accttacgaa agcttaaatt ttgctcgcag gcgatctgct tgggcttttc
    17041 ctattacctt atctaacaaa taggtacgca gactcataac catataaagt ccacccccca
    17101 tggcaccgac aagagctaca taaaagaagc tccacaaacg tccacttggt tggaagaaaa
    17161 atcctaacag ccactggatg gttcctatta acagaaacat gactagggtc agcaaactga
    17221 ttaaaatggt tcgcttcaaa atcaccttgc gcttgacacc agttacttta caaatatccc
    17281 gatacatcaa gacgttagga atgatgagag caatggttgt tgaaatcaaa ggaccataac
    17341 tgtggaagag ggcgatggta ggtagttgca agactagctt ggcaatagaa ccatagataa
    17401 aatagagaac ggcctttcgg ttgcggaaca tggcctgaag cattggagac aagaccatgt
    17461 acaagcctaa aataatagac tgcaaaactg caaagacaaa taagcccaga gccaaactat
    17521 ctggcttacc atagaagact gtatatagag gttctcctac cataaccact ccaaccgttg
    17581 ctggtagcaa gaacataaag agtagggtga gactgtcctg aaccagacga gaagctgctt
    17641 tcaagtcccc cttgacatag ttttccgtca aaagtggcaa accaacactc ccaatcgaaa
    17701 cccctacaga aatcaaaatc atcgtgattt tattaggatt ggctgagaaa taagaaaaca
    17761 tgacaaccaa gtcctcattg ctgtagttgg taaaccagct catactattg ataaaggtca
    17821 gctgatccaa aatctggaag agctggatgg cagaccctgt caggataaaa ggaatggctt
    17881 ccttaatggt atcaaccaag agacgcttac tgttaatctt atctcctgtt tcaaagactc
    17941 ttttgagtga accttcttgg gcaaggaaat aaatcaagac tgcaaaactg gctaccatac
    18001 cgacaaaggc agcaaaggtt gattgggtaa cggctgctag ataatctcct gaaccgagct
    18061 tcataatgat aaaggttgct aggagcatcc agataacacg aatgacctgc tcagcaattt
    18121 ggctcatggc atagggtttg aggttattca tcccttggaa aaatcctcgg ataacactca
    18181 tagacgggaa aatcaagact ccccaagcca agctttgcat gattgggatc aagtctttgc
    18241 ccacgccaga caagtctgct agccaaggag caaagacata caagactaaa gcaaaaacca
    18301 ggcctagtcc tgtcataaag cctaagaagc tccgaatcag ggcaaagcta tgctcttctt
    18361 ctcgcatggt attatacttg gcaacttgct tggccaccgc aactggaatc cccgctgttg
    18421 aaaccaacaa gaaccaagca tagatattgt aacccatggt aaagagacca tttgccttag
    18481 ctgcataagc ccccatccag atgtaccaag ggataatgta aacagccccg agtaggcgac
    18541 tgataaagtt actagccgtt agccaagcag tcccccgtaa catctgggcc tgctggtgat
    18601 tgttttcgtg cgacatagat tcctcattca attttgatag ctaggaaaaa ctccttatct
    18661 tccattataa acttttcctt gttacttgta aatttacgac tttcggttta caatagaaag
    18721 tatgattaag attgaaaccg tattagatat tttaaagaaa gatggccttt ttcgcgaaat
    18781 tattgaccaa ggtcattacc actacaacta cagcaaagtt atttttgata gcatcagcta
    18841 cgacagccga aaagtaacag aagacactct ttttttcgca aaaggcgctg cctttaaaaa
    18901 agaatacctt ctttctgcta taacacaagg attagcttgg tatgtagctg aaaaggacta
    18961 cgaagtcggt atccctgtca tcattgtgaa cgatataaag aaagccatga gtttgattgc
    19021 catggagttc tatggtaatc cacaggaaaa actcaaactc cttgccttta ctggtactaa
    19081 gggtaagaca acagcagcct atttcgccta taacatctta tctcaagggc atagacctgc
    19141 tatgttgtcg accatgaaca caactcttga tggcgagact ttctttaagt cagcgttgac
    19201 aacccctgag agtattgacc tctttgacat gatgaatcag gctgtgcaaa atgaccgtac
    19261 ccacctcatc atggaagtct ccagtcaagc ctatctggtc aaacgtgtct atggtctaac
    19321 ctttgatgtg ggagttttcc taaatatcag cccagaccat atcggcccga ttgaacaccc
    19381 tagctttgaa gactatttct accacaagcg tctcttgatg gaaaatagcc gagcagtcat
    19441 cattaacagt gacatggacc acttctcagt cttgaaagaa caggttgaag atcaagacca
    19501 tgatttctat ggtagccaat ttgataacca aatcgagaat tccaaagcct ttagcttttc
    19561 agctacgggt aaactcgctg gagattatga tattcaactc attggcaact tcaaccaaga
    19621 aaatgcagtt gctgctggac ttgcttgtct ccgtctcgga gcaagtcttg aggacatcaa
    19681 aaaaggcatc gctgcaaccc gcgttcctgg tcgtatggaa gtcctcactc agaaaaatgg
    19741 agccaaggtc ttcatcgact atgcccacaa tggggatagt ctgaaaaaac tcatcaatgt
    19801 ggttgaaact catcaaaccg gaaagattgc tctggttctg ggatcaacag gaaacaaggg
    19861 agaaagtcgt cgtaaggact ttggcctcct cctcaatcaa caccctgaga ttcaagtctt
    19921 tctgactgct gatgacccta actatgaaga cccaatggtc attgcagatg aaattagtag
    19981 ctacatcaat catcctgttg aaaagattgc ggatcgccaa gaagccatca aggcggcaat
    20041 ggctatcaca aatcacgaat tagatgcagt tattattgcg ggtaagggag ccgattgtta
    20101 ccaaatcatc cagggcaaga aagaatccta cccaggagat acagccgtcg cagaaaatta
    20161 tttataagaa tagaaaaaat caagggaaaa tgaaaccctt gattttttcc tattctttag
    20221 taaaaacgtt tttcaaacct tcaacggcac cttctacagc accttttgcg tcttctacaa
    20281 cgtcttttgc cttagcaact gttttttcaa cagctccttc aagttctgtc ttgctgtctc
    20341 cagtaacttt accaaaacct tctttgacag cacctgttgc ttgttccaat ttgttttcaa
    20401 gtgacatatg attgtctcct ttagtttatt ccgatatgtg ttaccggtta catatagttt
    20461 ataccgaata ctaaggaaag tcaaacaatg ttctcagaaa caagaaatca cgctaagtag
    20521 aaagttaatc tctccttatc aaaatcgata gccaactcat actttctatc ttcattttgc
    20581 acaatatagc ctaagacaac caaactgtcc acaaagatat cacggcattt ctgcataagc
    20641 tggtcttttt tgagaaattt caacaaaaaa gccgtcatat acttgagggc atactcagga
    20701 ttaacatctc ctaaaatgtc atagagctcc tgctgttttt ctgtcaaagg atactgctgt
    20761 ttgaccttgt aaaaataatt ggacagggtc attttaatgc gcgcaaagtc cgtcttttca
    20821 actaaaatag ctgcattgat ttgattgcgc aattccgtct caaaactctg ctccaacaag
    20881 gcttgataga ccggactagc ttctctgaca aaaatctctt gatccagttc aagactatca
    20941 agtgattcaa gcgtaggaaa attaaggtaa tggcgcttat tttcacatag aatcacatcc
    21001 tcatactggt ccagatagcg gatcaattct ccaaaaatgg ctgtctcgtc aaacgagatg
    21061 gattaaaaat ctgaatcacg aagattcctt tctttacatt gtaacagagg cgatgctgcc
    21121 aactgactag gattggtccc agcttggttc agaggaacag gcagacctag ttctatgtaa
    21181 tactccctcc aaaaatcact aatctcctgt tccccatctc caaatttcat aggaatagtt
    21241 tcaaaaatag gtaggatttc tgctatatac tgggagcagt agaaaccagc tgcatctgga
    21301 tagaaagaag cattgtaggg tgctccaaga tgtttgcaag ctctttcctt caccgactgg
    21361 atatccattt ctgggtaaac atagaggtcg tataaatgat tggactcaaa gaagtctgcc
    21421 ggttcttgac agacaacacc agcctgtcca ctagcatgat aaatcatccc atccaaataa
    21481 atggcaacat ggctatagtt acctgtggaa gtctggatgg cctgtcccat gtctgaccca
    21541 tctctcacaa aaatcaaatc gccattttct aacatacttc actcctagaa aaaaggagcc
    21601 gaaactcctt tcgatataag gcaaactaga ctttccgatt ttgagctgac acccaaaatc
    21661 ttacgcatta aagctttcag tcaattgagg taccacttgt ttcttacgtg aaacggcacc
    21721 agcaaggaag gcatgattgt tttcaagttt gaagttgaaa gccgcttcga ccttgtccat
    21781 attggcacca agagccaaga tttctgagtt tgagttgacg atatctgtaa tcatcaagac
    21841 aaagtcagag tagccgtttg attcgttggc agcttgcatt gcagcttcaa tttctgcttg
    21901 gcgttccaaa acttcagcga tgtcaactgt gttcacttgg gcaacacgga cattatttcc
    21961 gttgagttca aaagtcttag catcgatgtc aatcaattct tcagcagatt tgctagccaa
    22021 gttggtacca gctttcaaca ttgccaaacc atattcttcc aagttcacac cagccaattc
    22081 agccaattca ggagcaatga ttttatctgt tgggtgtgtt gttggtgatt tcaaaagaag
    22141 ggtatctgaa atcaaacctg aaagcatcaa acctgcaatc tctttaggca cagctacacc
    22201 atgttctttg aacatacggt aaacgattga agacgctgat ccaactggct ccaaacgcat
    22261 gtaaagtggg cttgcagttt caaagttagc cacacggtgg tggtctacaa caccgtaaac
    22321 ttctacttca gcgatatctg atacagattg ttggaattca ttgtggtcag tcaagataac
    22381 ttgctctgcc ccctctgctt tggcagaagt gataacacgt ggtgcttcca caccaaaata
    22441 gttcaagaca aaggctgttt cttcatttgg agttccaagg gcaacagctt ccgtatccaa
    22501 accgtaagct tcttttgcaa ggtaggcaaa agctacagat gatccgatgg catctgagtc
    22561 tggattttgg tgaccaaata ctagaatctt ggacatgata atacctcatt ttgtttattt
    22621 tctttattgt agcatttttt tcgctttttg acaaaggtaa gaggagtcaa aggactcccc
    22681 acgattcttc aaaataactg agtaaatttc tatcttgatt ttcagataaa aattcttcct
    22741 tctgtggcct cttcttacgc ttgagaagag cttcagccga catggcttct tccttactgg
    22801 caaaaccttg agcatagata agtttgactg gcaagcgtgc tcgtgtatat ttggctccct
    22861 tcccactatt gtggatagcg aggcgtcttc tcatatcagt cgtatagcct atatagtagg
    22921 atccatcacg acactccaga acgtacatat aagccttatg atccataata aatctcttcg
    22981 atttcgggcg tataagagcc atcatcattg tggacaatca aaggaggtaa gaccttaaag
    23041 ccacttgttg agccatcctt gatcgcctca atcaaaagca tattggcttc cttttctctt
    23101 tttggataaa caaactgcag gcgcttaggg gctagattat gtcgttttaa cgtatccaaa
    23161 atatccagaa gtcgatcagg acgatgaacc atggccaaac gcccattaga cttgagaata
    23221 ctctgggcac tatgacagat ttcttccaaa ttagtcgtga tttcgtgtcg agccaagaga
    23281 taatgttcac tctcgttcag attagaataa ggatccacct tgaaataggg tggattacac
    23341 aaaatcatat ccaccttact cccctgaatg tgagcaggca tatttttcaa atcatcgcag
    23401 atgacctgca tttgctcctc taatccattc aaacggacag agcgttcagc catatccgcc
    23461 aaacgctcct gaatctcaac agacaatatc tgtgcttgag tacgagtgct agcaaaaagc
    23521 cccactgctc cattcccagc acagaaatcc acaatcaacc ccttcttagg aaaacgtgga
    23581 aatcgtgata agagaacact atccaccgaa tagctaaaaa cctctctatt ttgaatgatt
    23641 ttgatatctg tcgaaaagag ctggttaatg cgctctcctg attttaataa ttgttcttct
    23701 tccatggtcc tattatagca aatttatatt aacattacaa aaaatataaa actctaaact
    23761 acttcttctt ttttaaatgg tgcagggctt ctccagtcca gattggtagc attcgtcgaa
    23821 agggagcaaa accgtagtta aagcggtcgc ttgaaaagcg tctccgtcta ggaaactggt
    23881 acttttcttc ctccaaagtg cggatagaaa gactggcttt ccctgtaaat tcatctaaat
    23941 ccactacctg aacttgaacc tcttcatcga ctttcaaggt ttcatgaata ttttcaataa
    24001 atcctgtccg aatctctgaa atgtgaatca gccccgtatc acccgtctct aactcaacaa
    24061 aggcaccgta gggctgaatc cctgtaatac gcccctttag cttatcaccg attttcatct
    24121 tagtcctcga tttcaatagt ttcaattaca acatcttcaa ctggcttgtc catagctcct
    24181 gtctcaacag cagcaatgac atccaagaca gcgtaagatg cttcatcagc taactgacca
    24241 aaaaccgtgt gacggcggtc taggtgaggt gtcccacctt gattggcata gatttctgca
    24301 atcggttctg gccaaccacc acgagtaatt tctttcttag aataaggtag gtgttggttt
    24361 tgcacgataa agaactggct gccgttggta tttggaccag catttgccat ggaaagagca
    24421 ccacggatat tgtaaagctc ttctgagaat tcatcctcaa aagattcgcc gtagattgac
    24481 tcgccaccca taccagttcc agttgggtct ccaccttgga tcataaagtc cttgataata
    24541 cggtggaaaa tgacaccatc atagtagcca tcttttgaaa gagatacaaa gttagccact
    24601 gttttaggag catgttcagg gaaaagcttg atacgtaagt ctccgtgatt ggtcttaata
    24661 gtcgcaagag gaccttctac tgtttcaatg tctacttgtg gaaaatgcaa ttctttttct
    24721 accataccaa atacttctaa ggcatcaaaa atgccatctt cttctaatgt ttttgtaata
    24781 taatctgctt tttctttgat tttatcatga gaaattccca tggcaacgct gattccagca
    24841 taatcaaaga gttccaagtc attgagacca tctccaaaaa ccatgacctt ctctggtttc
    24901 aagccaaggt gttccacaac cttttccacc cccgtcgctt tggagcctga aatcggcaca
    24961 atatcagacg aatgttgatg ccaacgaacc atgcgaagtt tgtctgagag actgtcaggc
    25021 aagtgcaagt catctccctt atcttcaaaa gtccacatct gatagatatc ttctttttca
    25081 tggaaatcgg gatctacatc taagtcggga taaattggat tgatagcttc actcatcata
    25141 tcggtgcgag tcgacaactt ggcatcatga ctcccaacca agccatactc aattccttct
    25201 tgcttagccc aagagatata ctcctcaaca tctgactttt caatctgatg ctgataaatg
    25261 acctgacctt ttttatcttc gatataagcc ccattcaaag ttacaaaaaa gtcaggcttg
    25321 agatcacgaa tctctggaac aacaccaaaa atgccacgtc cagaggcgat tcctgttaaa
    25381 attccttttt cacgcaactg tttaaaaaca gtgggaattg tagttggaat aaaccctgtc
    25441 tttgaattcc gcaatgtatc atcaatatca aaaaagacaa tcttgatctt ctttgccttg
    25501 tatcttaatt tcgcgtccat ctcactacct ctttcaatct aactctttcc attatatcat
    25561 aaagtaggca aatcccctat tttcaaaaag tttatcattt ttattttaat ttcttggatg
    25621 agaaaagaga catatttatg aaaaagctcc atcgtgcttt taatgtgttc tcttgttttc
    25681 aaactcgtaa aaagggagcc actgagccta actcgctctc tcatttcaaa gcttgtgaaa
    25741 aaagacccgt tggggtctta attcgctttc ttgttttcaa gctcatgaaa aagagaccca
    25801 actgggtctt ttctttaatc ttcgtttacg aaaggcatca aagccattac gcgagcgcgt
    25861 ttgatagctg ttgttacttt acgttggttt ttagctgaag ttcctgttac acgacgagga
    25921 aggattttcc cacgttctga aacgaaacgg ctaagaagct cagtatcttt gtaatcaaca
    25981 tattcaattt tgtttgctgc gatgtaatca acttttttac ggcgtttgaa tccgccacga
    26041 cgttgttgag ccatgttttt tctcctttat aagtttagtt gtccattaga atggtaaatc
    26101 atcatctgaa atatccaatg ggtttgttgc tccaaatgga ttttcattac gtgaaaagtc
    26161 tggtactgaa tttgtaggtg ctgaatagtt tgcagttggt gcagagtaag ctccacctgt
    26221 gtgaccctca cgcacactac gtctttccaa catttggaaa ttctcagcca cgacctctgt
    26281 cacgtagaca cgttgtcctt gctggttatc gtaactacga gtctggatac gacctgtcac
    26341 cccgataagt gagccttttt tagcccagtt agcaagattt tcagcctgtt ggcgccacat
    26401 aacgacattg ataaaatcag cctcacgttc accattttga ctcttaaatg tacggtttac
    26461 tgcaagagta aaagtcgcaa ctgctacatt tgatggggta taacgcaact cagcgtcacg
    26521 tgtcatacgc cctacaagta caacattgtt aatcatagtt taccttctta cgcgtcaatt
    26581 ttgacgatca tgtgacgaag aatgtcagcg ttgatttttg aaagacggtc aaactcttta
    26641 agagctgcat cgtcatttgc ttcaacgtta acgatgtggt aaagtccttc acggaaatct
    26701 tggatttcgt atgcaagacg acgtttttcc caagtttttg attcaacaac agttgcaccg
    26761 ttgtcagtca aaatagagtc aaaacgtgct accaaagcgt ttttagcttc ttcttcaatg
    26821 tttggacgaa tgatataaag aatttcgtat ttagccattg atatgttcct ccttttggtc
    26881 taatgacccc aagactttgc aaggggtaag tgaggttcgc tcacaataaa ctattatact
    26941 agaaaaaatt tttttacgca agtaaaaaca ctagaattcg aaaaaacgcc acatgggcgt
    27001 tttcctgttc ttatggtttg atacggtgca acatacgtgg gaatggaata gcttcacgga
    27061 tatgttttgt tcctgctgcg aaggttacca tacgttcgat accgatacca aatcctccgt
    27121 gtggaactgt accgtattta cgaaggtcaa ggtagaattc atattctgta cgatccatgc
    27181 caagttcatc catcttagcg acaagggcat cgtaatcttc ctcacgcata gacccaccga
    27241 taatttctcc atagccttct ggagcaagca agtctgcaca aagcacgcgc tctggatttc
    27301 caggaactgg tttcatgtag aaggccttga tggctgctgg atagttcatg acaaatgttg
    27361 gcacaccaaa gtggtttgaa atccaagttt cgtgtggtga cccaaagtca tcaccatgct
    27421 caagatgctc gtagtcagca tcttcatcat tttcatgctc ttgcaagagg tcaatggctt
    27481 gatcgtaagt gatacgtttg aatggctctg caatgtagcg tttcaagagt tctgtatcac
    27541 gttccaaggt ttccaaggct tgaggcgcgc ggtcaagaac accttgtaga agagctttca
    27601 cataagcttc ttgcaagtca agcgactcat catgtgtcaa gtatgagtac tcagcatcca
    27661 tcatccagaa ttcagtcaag tgacggcgtg tttttgattt ttcagcacgg aaaactggac
    27721 caaagtcaaa gacacgacca agagccatag cccctgcttc taggtaaagc tgacctgatt
    27781 ggctcaagta ggctggcgtt ccgaagtagt cagtttcaaa gagttctgta gaatcttctg
    27841 ccgcatttcc tgaaagaatt gggctgtcaa acttcataaa accgttcttg tcaaagaact
    27901 cataagttgc atagataata gcgttacgga tttgcaacac agctacttgc ttacgagagc
    27961 gtagccacaa gtgacggtta tccatcaaaa agtctgttcc gtgttctttt ggtgtgattg
    28021 ggtagtcttg agattcaccg atcacttcga tgtctgtgat gtccaactca tagccaaatt
    28081 tagaacgttc gtcctctttg acaatacctg tcacataaac agacgtttct tggctcaagc
    28141 gtttgataac atcaaacttc tcaagtccca cttcttcacc aaatttttcg acaaagtttg
    28201 gtttaaaagc cacaccttga aagaaggctg ttccatcacg caattgtaag aaagcgattt
    28261 ttccttttcc tgatttgttg gcaacccaag cgccaatcgt cacttcctga ccaacatagt
    28321 cttttacgtc aataatcgtt acacgttttg tcattatttt tccttttctt ttttattctt
    28381 tatggcaaac cacctctata ttgttcccat ccaggtcaat cataaaagca gcatagtaaa
    28441 tcggatgctc acttcgataa ccaggagccc cattgtctcg cccacctgcc tctaagccag
    28501 cctcataaca agcctgaact tcttccttat tttctgctaa aaaagcaaaa tgaacaggat
    28561 cttgtgttcc ctgagtcagc caaaaatcac caccaggatg agggctgttc ggggatagaa
    28621 aactaattag agaactagtc ttaaaagcca atttatagtc caaaggagcg agaaaactcc
    28681 tataaaatcc ttctgaaatt tgtaaatcct ttaccttaat ctcaaaatga tcaatcattc
    28741 tcactaccca taaatgcttt caagcgttcg actgcttctt taagcgtgtc taggtctgtc
    28801 gcatagctga ggcggacatt ttctggtgct ccaaatccag ctcctgttac caaggccact
    28861 tcggcttctt ctaagatagc agttgtaaag tctgtcacat ccgtgtagcc tttcatctcc
    28921 atggcctttt tgacatttgg gaagagatag aaggcccctt gcggtttgac cacttcaaat
    28981 cctggcacct ctgcaaggag gggatagatg gtattaagac gttcctcaaa ggcctgacgc
    29041 atgctttcta cagtatcttg ctcacctgat agagcctcaa ctgctgcata ttgggctact
    29101 gctgacggat tcgaagttgt ttgacctgca atcttggaca tggcagcgat aatgtctgct
    29161 tctccaacgg cataaccaat ccgccaacca gtcatggcat aggttttaga aacaccattg
    29221 atgaccactg tttgcttgcg aatcgcttcc gataggctag aaatcggtgt gaactcatga
    29281 ccattataaa ccaagcggcc atagatatca tctgctagga tgagaatatc attttctaca
    29341 gcccagtttc caattgccaa gagttcctca cgggtgtaaa tcatacctgt gggattagat
    29401 ggcgaattca gcaccaaaac cttggtcttg tcagtgcgag ctgcttctaa ctgatctacg
    29461 gtcaccttaa agtgattgtc ttccttagta gaaacaaaga cgggaacgcc ttctgccatc
    29521 ttgacctgat ctccatagct aacccagtat ggggttggga tgatgacttc atcacctgga
    29581 ttgaccgcag ccataaagaa ggtatagaga gaatatttgg ctcccgcagc gactgtcact
    29641 tgatttgacg ctacagaata gccgtaaaag cgctcaaagt agctattgac cgccgcctta
    29701 agctctggca gacctgaggt tactgtataa aaagaagcac gcccatctcg aatcgatgca
    29761 atggcggcat cttggatatt tttgggagta gtgaaatctg gctcacccaa ggttagagac
    29821 aaaatatctc tgccctcagc cttcagtgct ttggcacggg ctccagcagc caaagtcaca
    29881 ctttcttcca tttctaaaac acggttggat aatttcatag gccctccttg ttgaccaatg
    29941 ctcctgtttc aaaatctact agataaaaat cagatcctga cttgacttcc cagattggct
    30001 tatcttgata acgaccaaag ataatcttgt caatttcgcc agctcccttt tccttagaaa
    30061 ccgtttctgc tttttcttgt gaaacaccct gatttagctg ataaacgtaa atcttatgat
    30121 catcttttcc aatcagaaca gcaagtgctt cttgctgttt attacgacca agaacgctgt
    30181 aataagattc caagccattg tataaatcaa cctgatcggc ctgctctaat cctgcatact
    30241 gctgagctaa tttttctcct tcacttttag ctgtttgata gggtttcatg ctaagagaaa
    30301 ccatatacag aaaggaagca ctgataacca caaacaaaat cgtcatccct agaccatact
    30361 gccacagtag attatttttt gctttgtttt gtcttttttt cactcgtcta ttttaccatc
    30421 tattaagctt tattacaagt gaatataaga atactcttcg aaaatctctt caaaccacgt
    30481 cagctttatc tgcaacctca aagctgtgct ttgagcaacc aattctattt ctcccttcaa
    30541 acaaaaccga ttttgaaagt gaaacagttc ttactttttc agtcacaaat gactagagtt
    30601 tccgaaattt tacaattttc aaataaactc tgagcaaatt tcttgcaagt tcttttgttt
    30661 tgttgtaata tattttataa caacgagaga gttctcgaaa ttttaagaaa aaggagacac
    30721 atcatgtcta aaaaagtatt atttatcgtc ggatcactac gtcaaggttc tttcaaccac
    30781 caaatggcgc tcgaagctga gaaagcactt gctggtaaag cggaagttag ctaccttgat
    30841 tattcagccc ttcctctctt cagccaagat ttggaagttc caacacatcc agctgtagct
    30901 gctgctcgtg aagcagttct cgttgcggat gctatctgga ttttctctcc agtctacaac
    30961 ttctctatcc ctggtacagt gaaaaacttg cttgactggc tatctcgtgc ccttgacttg
    31021 tctgatacac gtggcgtttc tgcccttcaa gacaagtttg tcacagtatc atctgtagcc
    31081 aatgcagggc acgatcaact tttcgctatc tacaaagacc tcttgccatt tatccgtaca
    31141 caaggcgttg gtgatttcac tgctgcacgt gttaatgact ctgcctgggc agacggaaaa
    31201 ttggttcttg aagaaacagt cctaaactca cttgaaaaac aagctcaaga cttggtcgaa
    31261 gctatcaagt aactaacact caataaaaat caaaaagcaa actaggaagc tagccgcaag
    31321 ctgctcaaaa cactgctttg aggttgtaga tagaactgac gaagtcagtg acatatatac
    31381 ggtaaggcga cgctgacgtg gcttgaagag attttcgaag agtataacat aataaaagcg
    31441 aacaagacta cttttctgac actcagaaga ctagcttgtt cgcttttttt ctcatttata
    31501 aactaaaaca gctgatgata catattgcca aatacaaaat atctgatttc tatacttcct
    31561 ttacaaaaac caatccctgt ggttgtgaca aatcttctcg gtaaacaaat ccagcaaagt
    31621 tcaagcgacg tgcttccccc acagtttgta cttgattttc tattaaagct gttagaaagg
    31681 ccccgcgcgc tttcttggag atagttgagt gaatcttcag ctgaccgcct ctatcctcca
    31741 tgaatttgaa ggtcaccatc tttgctctga tttccttaga aaatacagtc tcaaactctg
    31801 atgacaagag agagaaaatc acttcttcct tcttcagagc ttcatcatag actgccttcc
    31861 aatggctctt caaagtctta ccagcgactt ttaatttcat caaaaaatcc aaacggtgag
    31921 gagccatggg tgacaaggct ggaacaacac cgtacaaagc cgaggtaatg aagacatgat
    31981 tttcaagata atcttgttcc gcctcggtca gcttatctct cttaatgttg cggtacataa
    32041 gcccatcaaa aagtttcaag gctggatagt gttgagcagt ttgccttttc aaagcttgga
    32101 tattttgaaa ttcttccgtc gctttctcag ctgatacctt gtagaaactc tccaattgac
    32161 tggcagaata gagagccaag gcatcaagca cggcctgact ttctggtttt aaaggagttg
    32221 cctcgatact tggcaagtct gtgttcattt cttttgctgt tgggattaaa attttcatat
    32281 tgatagtgta gcatattttt tagccacaac caagaaattc atttgaaaaa cctcggtttg
    32341 actgaggttt ttctatttat ttgggccatc ctaaccagac agccgcgaga acaagggcta
    32401 tgccagctaa acttgttaag atagataaga atttatcttt tttctccttg aactgagaaa
    32461 aacctatctt caaagcgagc agtccgagta gcattgaagc aaccatcaaa taaaaaccca
    32521 tttctttgtc ctccattagg cttaatttac cttattataa catatattta ttaaataaac
    32581 cttttttata ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggctgctcaa
    32641 aacactgttt tgaggttgca gatagagcta gagattttcg aagagtatta ttgtacttta
    32701 aaggtcttga gataattgtc ttttcctact tgaccttcga aggttttacc attttcaagg
    32761 taaggaaggt catcggatac tgaagccttg accttgtata tcttgccatc aactttaaag
    32821 aagtagacag tgtctccctt gataacagct gatttgaggt ctgctactac tcccttgatg
    32881 ctttctgtcg ttgcattgtc aatttcaagg tcgtttttat tggcatactt gctgagcatc
    32941 tcttccactg tagtagcaac gataacattt tggtactcga ctgcgtctac cagggcgtac
    33001 tctttgacca agccagcatt gtccttcaag cccatgatgt agagaggctt gtcattgagg
    33061 ttgatgagga ttgggaaggt tgctttgtag gatttctcct gaacagcacc ttctgctgat
    33121 tcacgggctg attcttctgt cgcagaagcc aagctatact tagtgatttc tcctgttcgc
    33181 atattttcaa ggatgaaacc aagattactc tcatccgcat tagccgacgt cacacctgtg
    33241 tagagataga tgtcattacc gatagacaag taattatagc ccttggtagt ctgggtcacg
    33301 tttttcttgg aaatcatggc attcaagaaa ccgtccttgt acttgccgtt gtagttgatt
    33361 tgctcaatgg tttcctctgc tggatagatc ctgtccaccc attctggaac atctgataag
    33421 ctgtattcct tggtttctcc atttgtagca tccaagataa tgactgaagc aggacgagga
    33481 acagcaagtc caaattgctt ttggtaaacc gttgctacat agaaaggatt gccctcatcg
    33541 tccacctcaa aagatggagt tttaaagatt ttggtcgggt acttcaagcg caggtgacgt
    33601 ttgacatcac ggttaaaata ctccgagtct gaatacttga ttggtgtctt caagtccacc
    33661 aaatccgcat ttccagttac catgtccacc ttgatatact caccgattcc cttggcttga
    33721 ttgttaaacc atttgatagg gtctgcatat tctagtggtg tgacccgata aggtttccca
    33781 tcaattgtca attgggtata ggtatctgcc gctacgtatt gcgacacctt atcggttagg
    33841 gaacccaagt agcggtctcc aattttttca gcagtacttc tatctaggat aggaacctta
    33901 ctggtgtcac tcctaggaaa ttcagtaaag tctttttccg taaccgtgac tacattggca
    33961 taatttttag cctgaaacat gctggaagtt accaaggaaa ccaaagctgc caagagaaga
    34021 attcctccaa tcgaagctaa cagaattttc cctaaccgat tgattttgaa accctcaaga
    34081 tttaaggcag cttccgcctt accgtggcgc acatgaaccg ttttgacaag gtttatcccc
    34141 ttgccaaagc caaataagat tgccacaact aacaaatgcc cacagaggaa gaagagaaat
    34201 tcccagctgg tcaggttaag gggcggtaaa aagatatacc aggtcgttgc gataaaaata
    34261 agttcaaaga ctattcgttt catttgcttt cctcctaaat gattcgtcct tccaagtgat
    34321 ccagctcatg ctggcaaatc tgagctggga agcctgtcaa ggtaatggtc tgttcctgcc
    34381 acttgctgtc acgataggca acccttatgg tttcataacg cttagttgat ctcacgccta
    34441 ccaaggacaa acagccttct tctgcctcat aggatccttc aaaggacaga agcactgggt
    34501 taaacatgac cacgggaacc aagccaagat taaagataat cacgcgcttc tgcaccccaa
    34561 tcatattggc agctagacca acacaggtat catgatttgc taagagtgta tcctgcaaat
    34621 ctctggcaag ataaaggtcc tcctgacttg ccggctgaga cacttgagat aaaaataaga
    34681 tatccttcac aattttcttt tccacttcct cacactcctc ttgcttttta ctatattata
    34741 gcaattatag cacaaaagcc gataactgca aaccctttcc ctcaactgta gcaaaaagcc
    34801 atccgaagat gacttttttg ctatttaatt tctgtataag ttacttccaa gccacgctta
    34861 acagctggac gattggcaat tttttctgcc cattttacta gattttgata acttgaggca
    34921 tccaagaatt ttgcagaacc ttggtaaaga tttccttgaa ctaactgtcc ataccaagac
    34981 cagatagcaa tatctgcaat cgtatagtca ttgcctgcaa tataaggttt ctgagccaat
    35041 tccttatcca ataaatccaa ctggcgtttc acttccattg taaaacggtt aataggatat
    35101 tccaattttt caggagcata attgaagaaa tgtccaaatc ccccacctag aaaaggtgct
    35161 gcacctgctt gccagaatag ccaattcaaa acttctacct tttccacagg attacttggt
    35221 aaaaaggctc caaatttctc agcaaggtaa agaagaatat gagcagactc aaagactctt
    35281 acatcttcag tacctgactg gtccaataag gctggaatct tggaatttgg attgagcttc
    35341 acaaagtctg atccgaattg atccccatcc atgatagcaa tcttatacaa gtcgtaagcc
    35401 gcttccttaa aaccagcttc tagtaattct tccaataaga tagtaacctt cacaccattt
    35461 ggtgttccca gtgaataaag ctgaaaagct tgttctcctt ttggcaagtt ttgttcgaaa
    35521 cgggcaccta ctgttggtct gtttagcccc gtaaaagctc cttgattact agcttcatcc
    35581 tgccatacgg tcggtaattg atatgctgac atccgaaacc tcccttaaat cgcattcttg
    35641 tcaaaaccga gtttgcgttg aataaactta acgatttcga cgatgataat cattgagaag
    35701 cttccagcca taacaattcc ccattgtgac aagtctagtt tggttacgtg gaagattcct
    35761 tcaagcggtt ctacaacgat tgttgccatg agaaggataa aggataccaa gatggaccag
    35821 ttaaaggtct tagacttgaa tgggccaact gtcaagatgg attggtagac agacttgaca
    35881 ttgtaggcat ggaagagctg aatcaaacca agggttgcaa aggccatcgt tagggcatct
    35941 gcatgaatag catgattgtc acccacatga actgggtaag caatcgcaag gccataaaca
    36001 ctcataacaa gagctgcttg gagtacacct tgataaatga tagaactcaa aacaccacct
    36061 gagaagaagc ttgccttgcg tccacgtggt ttatgattca tgacaccagg ttccgcaggt
    36121 tcaacaccta gtgcaattgc tgggaaggta tccgttacca agttaatcca caaaagatga
    36181 actggctgca agacgtccca accaaacaag gttgatagga agatggttaa tacttcagca
    36241 gtattggcag aaagtaggta ctgaatagtc ttttgaatat ttgagaagac cttacgtcct
    36301 tcttccactg cgacgataat agtcgcaaag ttatcatctg caagaatcat atcagaagcc
    36361 cccttagaaa cctctgtacc agtgattccc ataccgatac cgatgtctgc tgttttcaga
    36421 gctggggcat cattgacacc gtcacctgtc atggcaacga ccttaccttg tttttgccaa
    36481 gccttgacga tacgaacctt gtgctctgga gacacacggg cataaacaga gtattgacca
    36541 acaacttttt caaagtcttc atcagataat tcgttgagct cagcaccagt taaaacgtgg
    36601 tcttctgtat cgtttgcgtc aatgattccc aaacgtttgg caatagcttc tgcggtgtct
    36661 tggtggtcac ctgtaatcat aattggacga attccagctt ccttagccac acgaacagcc
    36721 tcagcagctt caggacgttc aggatcaatc atcccaatca aaccagtaaa aattaaatca
    36781 ttttcaagct cttcagaagt gagattttct ggaatactat cgataatctt ataagcacct
    36841 gcaaggacac gcaaggcttg atgagccatt tcagaattgt ttgtatgaat gagatttgta
    36901 accttctcat caatcggagc aatatcccca gccttatcac gaagaagaca acgttttaag
    36961 agttggtctg gcgcaccctt gactgctaca aggaaacgac catctggcaa tgggtgaact
    37021 gttgacatga gcttacggtc agagtcaaat ggcaattcag ctacacgagg atatttctct
    37081 aagaaacctt tgacatcata gcccttgtcc aaggcatatt ggataaaggc tgtttcggtt
    37141 gggtcaccaa tcaagttacc ttccacatcg attttcgtat cattggccaa gacaactgaa
    37201 cgaagtagtg gcatttcaag acctagttca atatcatcag ctgagtcatg tagaaccgca
    37261 tcgtagaaga ctttttcgac tgtcatcttg ttcatagtca gcgtaccagt cttatcagaa
    37321 gcgatgattt cagttgaacc aagtgtttca actgctggca acttacgaac gatggaatgt
    37381 cgtttggcca aaacttgagt accaagagaa agaacgatgg taacgatagc aggaagtcct
    37441 tctggaatgg ctgcaacagc aagggcaaca gaagtcaaca actcaccaag tggatttttc
    37501 ccttgaatga agacacccac tacaaaagta acaagggcaa tgaccaagat agcataggtc
    37561 aagaccttag aaaggttgtt caagttttgt ttgagtggtg tatcagtctc atccgcatct
    37621 tgaagcatac cagcaatatg accaacttca gtgtacatac ctgtattgac aacaacaccc
    37681 atcccacgac cataggttac gtttgagttt tggaaggcca tgttgacacg gtcaccaata
    37741 ccagcatctg tcgcaagctc gactgacaag tctttttcga ctggtacaga ttcacccgtc
    37801 aaggctgctt cttcaatttt aagagagttg gcttctagca aacgtaggtc cgctggtacc
    37861 acgtcacctg cttcaagggc aacgatatcg cctggtacca attctttaga gtcaatctct
    37921 gccatgtgtc catcacgaag aacgcgggca actggactag acatggattt gagggcttca
    37981 atagcttctt cagcttttcc ttcttggtaa acaccaaagg cagcgttgat gataaccaca
    38041 gctaggatga taatggcatc tgcgatatct tccccaccag aagtcacgac tgacaagatt
    38101 gctgccgcaa ctaggatgat aatcatcaaa tccttaaatt gctcgatgaa tttgaccaag
    38161 attgatcgtt tctcgccttc ttcgagttca ttgtgcccaa attcggcaag gcgcttttcc
    38221 gcctcacttg atgacaaacc ttgctcggtc gcatccacag cctgcaagac ctcttcaggg
    38281 ctctgagtat aaaacgcttg gcgtttttgt tcttttgaca tgtgtctcct ccttgacatt
    38341 gtgtgcaaaa cagactctct ttctgtcata tcttttcacg acaaacaaaa agagacctgt
    38401 taatcataac aagtctcgct gtttaagata gggccggaaa gcatactttt cagcataaaa
    38461 ttcggaatga cgacactatc acaggtttct gccagctact cccttgagta gtaccattat
    38521 accaaatttt ggggagtttt caaagagtaa aaactgcctt atttgaattt ttccttgaaa
    38581 accagtataa tggtagaatg ctatgtgact agaaaggaag ttgaatgaag caatctatct
    38641 caaatctcaa gttagctgag cgtggagcca ttatcagtat ttcgacctat ttgatcttgt
    38701 ctgcagccaa attagcagct ggtcatctcc ttcattcatc cagtttggtg gccgatggtt
    38761 ttaataacgt atcggacatc attggaaatg tggccctctt aatcgggatt cggatggcgc
    38821 gccagcctgc agaccgtgac caccgttttg gtcattggaa gattgaagat ttggcaagct
    38881 tgatcacttc tatcatcatg ttctatgtcg gtttcgatgt tctaagagat accattcaaa
    38941 agattctcag tcgggaagaa acggtcattg atcctcttgg tgcaactcta ggaatcattt
    39001 ctgcagcgat tatgtttgtg gtctatctct acaatactcg cctcagtaag aaatccaact
    39061 ccaaggcgct gaaggcagct gctaaggaca atctttctga cgctgttacc tcacttggaa
    39121 ccgccattgc catcctagct agtagtttca attatccgat tgtggataaa ctggttgcta
    39181 tcatcatcac tttctttatc ttgaagactg cctatgatat cttcatcgag tcttccttta
    39241 gtctttcaga tggctttgac gaccgcctgc tcgaggacta ccaaaaggct atcatggaaa
    39301 ttcccaaaat cagcaaggtc aaatcgcaaa gaggtcgcac ctacggtagc aacatctacc
    39361 tggatattac actagagatg aatcctgact tgtctgtttt tgaaagccat gaaatcgcgg
    39421 atcaggtcga gtctatgctg gaggagcgtt ttggcgtctt tgataccgat gtccatatcg
    39481 aaccagcacc tatccctgag gatgaaattt tagacaatgt ctataaaaaa ttgcttatgc
    39541 gtgaacaatt gattgaccaa ggaaaccaac tagaagaact cttgactgat gattttgtct
    39601 atattcgcca agatggagag cagatggata aagaggctta taagaccaaa aaagagttaa
    39661 attctgctat caaggacatt caaattactt ccatcagtca aaaaaccaaa ctcatctgct
    39721 atgagttaga tggtatcatc cataccagta tctggcgtcg ccacgaaacc tggcaaaata
    39781 tctttcatca agaaaccaaa aaagaataga gaaatccttt catgagacgg gatttttcta
    39841 ttcttttata ctcaataaaa atcaaagtgc aaattaggaa gccggtcaca ggctgtactt
    39901 gagtcggcaa tgtgaagccg acatagtttg cactttgatt ttcgaatagt cttaactatc
    39961 aaattcactg agatactcat agcgttcgta tttttcaagg agtgcttcat ttttctcatc
    40021 caattctttt tggagagtag ccagcttacc aaagtcagag ccgttagcct gcatttcctc
    40081 ttcaatagca gcgatacgtt tttccaaggt ttcaatatca ccttcaatac ttgcccactc
    40141 ctgcttttct tggtaggtca tgcgtttctt gtcttctcga accttgacca ctttttcctt
    40201 ttcggccttt tgcacttgat tggccatatc tgtttcaaaa gctttttcat caagatagtc
    40261 ggtgtaatga ccaaagaaag gacgaatctt gccatcctca aaagcgagaa tcttggtcgc
    40321 taccttatcc aagaaatagc ggtcgtgact gactgttaaa acgggacctg caaaaccttg
    40381 caagaaattc tccaagactg tcaaagttgc aatatctagg tcattggttg gctcgtctaa
    40441 aagaagaaca tttggttttt ccaaaagcag tttgaggaga taaagacgtt ttttctcacc
    40501 ccctgacaat ttctcaatca aggttccatg cgtcgaacgt gggaaaagga actgctccag
    40561 caactctgca atcgaagtcg tagaaccacc actggtcttg acctcctctg ccacttcctg
    40621 caggtaattg ataactctct tgctttcatc caagccctca atttgctgag agaaataggc
    40681 gatgcgaaca gtttccccaa tcacaacttg tcctttagtt gactcaagac ttcctgcaat
    40741 taagttgagt aaggttgatt ttccaacacc gttgtcccca acgattccga tacgatcttt
    40801 gacctgtacc aagagattaa aatcttgcaa aatgggcttg ttttcatagg caaaggaaac
    40861 atcctgaaac tcgatgactt tcttcccaat ccgactggtt tcaaagttca tagtcaagtc
    40921 tgtctcagca ctactgcctg aaacttcctt tttcagatca tggaaacgat tgatacgagc
    40981 ttgttgcttg gtcgcacgtg cctgcggttg tctgcgcatc caggccagtt cttgtttgta
    41041 gagttgttct tttttatgaa gtagagctgc atcgcgctcg tcctgttctg ccttaaggcg
    41101 aacatagtcc tggtaattgc cctgatattc tgtcaagcct gctcgctcca actcgaaaat
    41161 ccgtgttgac aaagcgtcta agaaataacg atcgtgagtg ataaaaagga cggtcttctt
    41221 agaatttttc aaaaagaggg tcagccactc aataatcgca atatccagat ggttggtcgg
    41281 ctcatccaaa agcaaaaggt cgtggttgcc aagtaagact tgtgccaact gtacccgtct
    41341 tctcagacca cctgacaatt ccccaacagg agtagataag tcttgaatgc ccaatttgct
    41401 aagaacggtc ttgacctgac tctcgatttc ccaagcttgg agagagtcca tctctgccat
    41461 gacacgttcc aaacgcgcct gcttgtcctc actatagtcg agcataatca attcatactc
    41521 acgaatgagc tggatttcct tgagttcact agatagaacc gtatccaaaa ctgtctttct
    41581 atcatcaaaa tcaggatcct gagtcaagta accaatctgg taatcatttt tagctgaaaa
    41641 aggactgaca tccccatcaa atccagaaac accagaaagg acgtccaaaa gggtggtctt
    41701 gccagtccca ttgacaccga ttaaaccaat tctgtctaag tcatggataa taaaggaaat
    41761 atccctaaaa acggtcttgt caccaacgga tttacttagt ttttcaacga taaaatcact
    41821 cattttttct ccctcaggta agcatggatg gcttcacgat tattctccaa ttctccatcg
    41881 acaatggcaa actcaatctc tgttaaaatc tctcccaagt ctgggcctgg ctgatagcca
    41941 tattccttga tcaaaatatc gccattaatc tgaatctctt tcttgtcatg gatagtcaag
    42001 ctttggtatt tttctgtgat ggcttgtagg ttgacttctt ttccttgagc ttgacgaaga
    42061 ttttcagcct gtaaaagcaa atctatatca aagcgataac aatctcgctt gctcaattct
    42121 ccattttcac gcagagccaa aataatcagc aaatcctgaa cttgcttggc aaactggcgt
    42181 gaggtcttcc aagatttcaa aaatgactgc gcattttcaa tctccaaagc ccatagtaaa
    42241 gccgcccagg cttgttcaga ggattcaaaa gtaaaatcag tctccaaatc aaacagtctg
    42301 ttgagcttgt cctggctaga tgccatatca gggagatagt cataagcttg actctcaatc
    42361 atggaagcca agccccttct ccaaaatgga gccagcaaga gtttatcaaa ctcgacgaag
    42421 gtacgctcta cagaaatttt ctccaaaagc ggcgtcaagg tcttcatagc tttaaatgtt
    42481 tctggctcaa gtgcaaaacc aagactagcc tgaaaacgga aaccacgcat aatccgtaaa
    42541 gcatcttcgt tgaaacgctc actagccact ccaactgctc gcaagacttg cttttccaaa
    42601 tcttctaaac catggaacaa gtcaacgatt tctcctgtct catccaaggc aaaggcgttg
    42661 actgtgaaat cacggcgttt gaggtcttct tctagcgagc gcacaaagga aaccgcactg
    42721 ggtctgcgat agtccacata gacatcctct gtccgaaagg ttgttacctc atactcctca
    42781 tccccatcta agaccaagac ggttccatgc tcgattccga tatcggctgt tcgcggaaaa
    42841 atctgcttgg tctcttctgg ataagaagac gtcgcaatat ccacatcgtg gatagggcta
    42901 tggagaaggg catctcgaac agagccccca acaaaataag cctcaaagcc tgcttcttta
    42961 attttttcta atactggtaa agccttctga aattcagaag gcatttgcgt taatctcata
    43021 ataagtgttc taatccatag acaagctcat gacgcttgac aacttcttta attcccaaat
    43081 tgactcctgt catgaaggag atgcgatcat aggagtcatg acggagggtc aacccttctc
    43141 cctgattgcc aaagatgact tcctgatgag ctaccaagcc tggcaaacga actgagtgga
    43201 tgcgcatacc atcaaagtca gcaccacgag caccagcaat cagctcttcc tcatctgctg
    43261 caccttgctg aattgactct cgaacctctg ccatcaactc agctgtttta atggctgttc
    43321 cactcggagc atcctttttc ttgtcatgat ggagctcaat aatctccaca tttgggaaat
    43381 atttggcagc ctgcgtcgca aattgcatga gtaagacagc acccaaggca aagttagggg
    43441 caatcaggcc acccaagtct tgggcacgag aaaattcttt tagctctgca atttcttcac
    43501 tcgtgaaacc agtcgttcca actactggag caaagccatt ttcaagagca aaacgtgtat
    43561 tttcgtaggc aacagctgga gtagtaaaat ctatccagac atccgcttca aaaccagcta
    43621 aatcagcctt atccttgaaa acaggaatac cctgccattc tgactcagac tcaaaaggat
    43681 ccaaaactgc taccaagtcc aagtctggat cagtcaatac catctgacaa gcagcctggc
    43741 ccatctttcc cttaaaaccg gcaataatta ctcgaatact catctctact cctgtccaag
    43801 atacaaagcc tgtaagaaca caaagtgaaa ataggaattc tgatcaagaa gtgtctactt
    43861 cttggaagaa ctatcttttt cacacagggt tccaggcgtg ttcaattatc aagatacaaa
    43921 ggaccttagc tgcccctgaa aaatagggaa tggcactgac tttccacgaa aggcaagaca
    43981 ggcatctttt ttcaagaggc aggtagtccg tgttcaattt ctaagattaa ctagcctaga
    44041 agtgccaact aaatcactgg aatataacct agagcaatac ttcctgctcc taggtgcgtt
    44101 ccaatgacac taccaaatgt agcaagtgaa acatccgaac ccaagccaaa atcaagcaaa
    44161 tgctgacgca attcttcagc cttttcagga gcattcccat gaatgacaat gacccggtat
    44221 tgacctgaag ccgttgtttc cttgataatt tcaattaagc gtttggtggc cttcttttca
    44281 gtacgaactt tttcgtaaac ttcaatcaca ccttgatcgt taaaataaag gattggctta
    44341 atgctaagca aattgcccaa aatggcagcc ccatttgaaa ggcgtccacc ttttaccaaa
    44401 tgatccaagt catctaccat gataaaggct gacgtacggc tgatttgaat ggctagctta
    44461 tcctgaatgc tggcaaaatc atcgccctga tcacgccaat taaagacgct ttcaaccatg
    44521 atgcctaggg gagcacttgt aatcaaagtg tctgggaaag caatggttaa gccctcatag
    44581 tcatcgacca tatactggat attttggtaa aaacctgaaa ttccagaaga taggaaaagc
    44641 cccaaggcat gtgtataacc ttgttctttg agcgaagtta agatttcatc taacttggca
    44701 atacttggtt gactggtctt aggcaattca gaagcctgag ccattttttg gtaaaattcc
    44761 tcagcagaca gattgatgcc ttcgacatat tcctcaccat caatattgac aggaatatcc
    44821 aagacaaaca agtcttctct ttgcaagatc tctgcactga gataagcaga ggaatctgtg
    44881 aaaacagcta atttcatatt agaactccaa attaattcct ggtaagtcta atgcaatttc
    44941 agtcacttcg taagtcaaac gattgagcat gttcaaacat ggacgagcca aggtttccac
    45001 ctcttcttgg ttcaattcac ttggttcatt gacaatacgg ccatcgatat ggtttacttg
    45061 tgagattgtt ccactaatga caaacttatc aaatacaatc ataaagctca agatgacaat
    45121 caaggaagtc acttgatttt cttggtcatg ttggagcaat tggaaattca catccacctt
    45181 ggtttcagga gctccatttt cattttccca ttcaaaatta cgtgcatcaa aatgatactg
    45241 actaacaaat tcttgttcac gtttaagatt catgtctttc tccatcggct acaatattat
    45301 aagctattgt accataattt tttattttca tctagttttc taggatttag tcaatcccaa
    45361 tttcagcacg aactacatct gtgatagtat caacatagta gtccacttct tctgttgtag
    45421 gcgcttctgc cataacacgc aagaggggct ctgttccact tggacgaaca aggatacggc
    45481 cgttccccgc catttcttct tccatcttct cgatgatggc cttgatagct ggcacttcca
    45541 tggccttttc cttcatgacg ttttccactc ggatattaac taatttttgt ggataaatcg
    45601 ttacttctgc cgccaactct gataagctct taccagtttc cttcatgatt ttagtcaatt
    45661 gaactgctga taattgacca tcacctgtgg tattgtaatc catcaagata acgtgaccag
    45721 actgttcacc accaaggttg taacctgatt ttctcatttc ttcaacaacg tagcggtcac
    45781 caactgcagt aactgccttg ttaatacctt cgcgattcaa ggccttgtgg aaaccaaggt
    45841 tagacataac agttgtcaca attgtatttt gagccaattg tcctttttca gaaaggtatt
    45901 ttccgatgat gtacataatc ttgtcaccat cgacgatgtc accattctca tcaacagcaa
    45961 tcaagcggtc actgtctcca tcaaaggcca aaccaataac tgacccactt tctttgacca
    46021 cttcttgaag ggcttctgga tgtgttgaac caacattaag gttgatgtta agaccgtctg
    46081 gtgtttcccc gataaccgtc aattgggcac caaggtctgc aaagatttga cgggcactgg
    46141 tagaagctgc tccattagct gtatccaagg caaccttcat tccatcaaga ggagttccag
    46201 ttgaaacaag gtatccttca tacttacgca agccttctgg ataatctacc aaaattccta
    46261 agccttctgc acttggacga ggaagagtgt cttcctcagc atctagcaag gcttcaattt
    46321 ctgcttcttt ttcatcatct agtttgaagc catcaccgcc aaagaacttg attccgttat
    46381 caagggctgg gttgtggcta gcagaaatca tgacaccggc acttgctcct tcagtttcaa
    46441 ccaagtaagc tactgctggt gttgcaagga caccaagttt gtatacgtga atccctactg
    46501 aaaggagacc tgccaccaag gccgattcca acatttcccc tgaaatacgt gtgtcacgtc
    46561 ctacaaagac tttcggcgct tccgtttcat gttgactaag aacatagcct ccaaaacgtc
    46621 ctagtttaaa ggctaattct ggtgttagtt ctaggttagc ttctccacgg actccatcag
    46681 tcccaaaata tttacccatt gttataaaat ccttttctat ttttaattcg tttttgaact
    46741 agttgctttc gttgacgaag atgtctccga tgaactgctt gtacttgaat ttgatgtgct
    46801 tgaacttggt gctactggtt ttgtagtcac cttcattatt gtatcaaacg gagtgataac
    46861 tgccggtaag acaacaccat tgcggtcgat tgcctgcaaa ggtactgaac cactgtaatt
    46921 acctgttatg cgttcgctag ttggcaagac agcgataatc ttatcaattc tatccaatgt
    46981 ctcttggtca ctcgtaatag acacttcttt atctgacacc atgacatttt caatttgtac
    47041 ccgactatca atttgactag ggtcaatctc tggtacaatc tttaccttat ccttctgagc
    47101 cttcttacca atcttgactg taattttttg cggagtcgcc acagcggtca gcccattggg
    47161 taaatcttca atgctcaaag gaacttcaat cgttccaaca ccggcatctg ttaggtcagc
    47221 agtaaccttg aatttacgtg tactttcttg catttcacta gctagcgata ggcgatttgc
    47281 cccagtcaag accactgata cttctgaagc aaaaccgcta ataaaatact tatcactatt
    47341 atagcgtatg tcaataggga catttgttac tgtattagta taggtttccg tttttacctg
    47401 cctagcactg gtactgtttt gaaaattcgt cgccgtagca tagacaaata agacacaagc
    47461 aaaaaagagt gaggatatga tatataaact attttttttc atgtttccat cctcctagca
    47521 atcgttcttt aaaactaaga cccacttcct cttttggaag taagatttca cgtaattctg
    47581 tttcaaattc atcaagtgtt aggttgtgct taaaccttcc attataggtt atcgaaattc
    47641 ctcccgtttc ctctgatacg acaaaagtca aggcatctga gacttctgat aaaccgatag
    47701 ccgcccggtg tctggtccca aattccttgg aaatccctgt gttttttgtc aagggcagat
    47761 aggcagacgt cacagcgata cgttcttctt tgataatcac cgcaccatca tgtaggggag
    47821 tgttgggaat aaaaatgtta atgagaagtt ctgcagaaat cttagcatcc aagggaattc
    47881 ctgtcgaaat atactcctgc aaggtacgta cacgctgaat agcaaccaag gccccgattt
    47941 tacgaggact catgtattca acagacttaa caaaggcacg aatcatctgt tcctcagcac
    48001 taataggggc attggaaaaa aaatctgtcg ctcttcccaa acgttccaaa ccagtccgaa
    48061 tctctggaga gaagataaca accgccgcaa taaccccata agtaataatt tgattgatta
    48121 accaagaaat cgtagtcaaa ccaatcatat ttgcaaggat ttgagctaaa ataaacacca
    48181 aaactccacg taccaaaatc ataatcttgg ttcctgcaat agcttttgta aaatggtata
    48241 aaatataagc aacaatcaaa atatcaatca gattgatagc tatcgtccat ggacttgcaa
    48301 acaaactggt ccaatattgc agattggata attgttgaaa attcatccct gatatcctcc
    48361 ctatcaaaac actttcgtcc tattatacca ttttctggca tttttttccc tatcctagtc
    48421 cattttacat tgaacaaaaa tatgataaaa taaactgact agaaaaaaca aaggagaaac
    48481 tatgtctcaa ctctatgata ttaccattgt gggtggtggt cctgtcgggc tttttgcagc
    48541 cttttatgcc cacctacgcc aagccaaggt tcaaatcatc gactctcttc cccagctagg
    48601 tggacaacct gctattctct accctgaaaa ggaaatccta gacgtaccag gcttcccaaa
    48661 cctgactgga gaagagttga ctaaccgctt gattgaacag ctaaatggat ttgatacccc
    48721 tattcatctc aatgaaacgg ttcttgagat tgacaaacaa gaagaagaat ttgccatcac
    48781 aacttctaaa ggaagtcacc tgactaaaac agttatcatc gctatgggtg gcggtgcctt
    48841 caaaccacgt ccgctggaac ttgaaggggt tgagggctat gaaaatatcc actaccacgt
    48901 ttctaacatt cagcaatacg ctggtaagaa agtgacgatt cttggtgggg gagactcggc
    48961 tgtggattgg gctttggctt ttgaaaaaat cgcaccaact acccttgttc accgcagaga
    49021 taatttccgt gccttggaac acagtgttca agccttgcaa gaatcatctg taaccatcaa
    49081 gacaccattc gcccctagcc aactccttgg aaatggaaaa acacttgata aacttgaaat
    49141 cacaaaagtc aaatctgatg aaactgaaac cattgaccta gaccacctct ttgtcaacta
    49201 tggtttcaaa tcttctgtcg gtaaccttaa aaactggggg ctcgacctca accgtcacaa
    49261 gattatcgtc aacagcaaac aggaatccag ccaagcaggt atctatgcta tcggtgactg
    49321 ctgctactat gacggaaaaa ttgatctgat tgcgacaggc ctcggagaag ctccaactgc
    49381 tgtcaacaac gctatcaact acattgaccc tgaacaaaaa gtacaaccaa aacactctac
    49441 tagtttataa aaaagaacca cgagtcacat agaattcgtg gttttataat tcatccgcat
    49501 ttaaaaatac ctttacatcg ttttactata tcttacaata ccttttaaaa cagctatatt
    49561 ttgagctttt aaataaatgt ttttacatca ttttacagag atttacgaca cttttgcccc
    49621 ttttttgccc cttttgagca aacaaaaaaa ccgcaagcct gagcctgcgg tgaaagaaca
    49681 atttagaaag tttcctttct atttatttaa ctgtaatcaa gccatctggc tctactgtga
    49741 actctggctt gtctgccatg ctaccgtctg gtttgaggta gtaccagcct gttccgtccg
    49801 ctgactggat aaaggcattt gataccatgg cgccttcttt agcgtctaag tagtaccagg
    49861 tgtccttgta cttgacccag cctgtcttca tggcaccttc tacatcaaaa tagtaccact
    49921 tctcagcgat tttcttccag cctgtagcca tttcgcctga gttgtcgaac cagtaccaat
    49981 taccgtctgt gtgcttcttc cagcggtctg aaagcatata gcctgagcca tcgaaataat
    50041 accaggtacc gttgattttc tcaaacttat cttttggata aaagccgtct gagtgtacgt
    50101 accagtagcc agtgccattt ttctgccagc ctgttgcagc gctcaagccg ttttcgatgt
    50161 cttgcttaaa ctgttcacgg ctaatgcccc aacttgcaag atatggatat ggatccacat
    50221 ggtctgagtg gttgtttggt tggttattgg tacagtattc atgcgtcttg atacctgcca
    50281 agtcgtctgt atcaagagtc ttcggcaagc ctgcttcgtc cgctagattg cgtagcaatt
    50341 cgatatagag gcgatagtca gccataaact cttccttagt tgaatggctt tcaatcagtt
    50401 caaccgctgc ataactctca gcattccaac cgcccccaac atcccaactt ccgttgttca
    50461 caggacctac ttgcatgatg cgaccgttcc caacaacgtg cgagaaaaaa cctaattctg
    50521 ggtctttccg ccagtgataa tccgcttcat tttgagcggt tgagttacgg ttgcctgttg
    50581 agtgggcatg tacttgtcga taaggctgca ccccaacctg gggcaagcct gttcgtagtc
    50641 tgcttgtatc gatatccatt actcttgtcc tttccaagcg tcgttcatct gtttcactgc
    50701 tgactctacg aaggtgtcta agtctttgtc agtcatgcta atattgtatt ttgtaagctc
    50761 agcacgaatt ttagcgcgag cctgtgccag tttttcatct cccttgtagc cagtttcagc
    50821 agctacctgc tccacggcat ttactgcatt tttggccaag atttcaacaa tcttgatggt
    50881 cttttctcca cctttttgaa ccaggtagtc cttgactgcc ctaactacaa cccctgccaa
    50941 aacgactagg atgctgattg ctccattagt aatgatttca gtaatttgtt gcatttgtta
    51001 ttctcctttt tcgatttctt ccatgcggtc gttcatgcga accatttctt tttgaatgtc
    51061 tccgaccgcg tgagtgattg tggttaattc tgtagtggtc ttttctaggt gagtcatcaa
    51121 acgctcttct cgtctattag agtcggcctt tgattgctcg tgcaaatcca taatcttctt
    51181 ctctcgcttg tccgaagtct tgataagata tcgaatgata ataaagaaaa gcaagataaa
    51241 caaaatcgcc caagctacct gactttgagc gattttttca gcttcttcaa ttggcataca
    51301 cacctcctat tctttaggtt ttaccgttgg atccgtccag tcaggattgc cctctgcatc
    51361 aaatttcatg atatagaatt catgattcaa cagaacggct acgttgattg ttgcgattgt
    51421 accaccccac tggttgaacg cccaaacggt ttcaacatcc tttaattggc gacggccatt
    51481 tacgatcaca ggacgttttt gaacatcacg atacatatag aagtcatcgc ttacattctt
    51541 gcaacgaatg aactctccat tttctttcat gtagcgcaaa gcgctcgcaa gatcaaatgg
    51601 ttctgtgatt tttgtaaggt ctagtaagtt atctgtgttt tgaattgttt ctgccatgtc
    51661 tattctcctt tgtctgctgg tttagtttgt tcatcaagca gagcttccag ctcatccact
    51721 cgtgcttgaa gtctttgatt ctcttccctt tgctcattca actgaatact caagatatta
    51781 cttgtaatca tcgaatttgt tgaagttgtt gacatttcac taattgtcat ttgtaaggct
    51841 tggttaagct gttctgtgtt cattttctaa gttctccaat ctgtgtgttc gttttctatt
    51901 ttcaagagca agctcttaaa ttgctttaag tgcgatattg gtcaacatgt tgttattcat
    51961 gctattgttt tctccatttt ttctattttt tgatttaatt cttgaatagc cttgattaag
    52021 taaggaacta aagcggtata gtcgatatgt agatagccat ctggattctc aggatctcgt
    52081 gagacaattc ttggaacgat ggtttcagcc tcttgagcta ttagaccaat ctcctcatgt
    52141 ttcttacttt cgatgaaatc aaatgcaacc attcttaatc tgttgatttt atccaaggct
    52201 ttcacagctg tatctgtgat gttctctttt aagcgtctgt ctgatttttg ttccatccaa
    52261 tacttcacgc taccgctacc gacctgattc caccaaacaa ccgcattcct tccgcctttg
    52321 ggattccaac catcaccaag cacatcttta cttccaagtt cgataccatt tgaaaacaca
    52381 ggagaacgag aaaaagtagt attcccatag aagtttgctc tcgatgaatt cgaaaaatcc
    52441 acttgatcat aaaaaccgac ttcattccta cagtacattt tcccatcagt attgacgttc
    52501 catgctttag gtccggcata gttccaatta tttccccagt tcgcccagaa ggctgtccgg
    52561 actccatgcc cggcaccatt ccccatacca acagagaact gattgacacc tgaaatccag
    52621 cgaccgccac cctggtcaaa ttgaccaagt gtgaatccac caattcgacc ttgataggct
    52681 tctaggaagg ttgaactaga aatgacggac tcaaccttag tagagaagat acgtttagat
    52741 gtcagttggt caataaaagc atcatttgca gttaattttt taataagcgc attgtcaact
    52801 ttcaacttct cagcagttac cgcttcagct tctaatatcg tagtcgtgac cgaaccagct
    52861 tcaaaattgc ccgttttcaa cttatcaacc atggcagact tgatgactgc tctgtcaatc
    52921 agggtctctc cagtgatgtg ggtcaatttc ccaacaaagc ggttatgtcc attggcgcca
    52981 agattgattc cagagatgat atctccagcc gagttgatgt tttgaactgc ccatgagcca
    53041 gttagtagag tcatttttgt ttgcgtggct tcaagcttct tattcgcatc tgcgaccaca
    53101 tcttctggat gtggttgcca tgttctaggt ttataacctt tgtacaagtc aacttctgta
    53161 atatacaaat cagctgttcc tgatgatgag ccattgttat caaaacgaat gtaagcatta
    53221 tccatttctc cggaattaaa agttactgag acatcttcgc atctagaggt agatagtttc
    53281 ttgctgctaa caactttctt aacgattgtg aatccatcgc tctcgcctgc tcttcgtccc
    53341 aaaatataaa catcatagct tgcgagagca ctgttgttaa atcctctaaa attcagtaca
    53401 tagtcagtat ttcgttcaag attaaaacgg tgactataca aaaagttttc gtttttagtt
    53461 gcattactta aacgcataag gtctttctgc ccgttgtgat aaaagctatg cttaaccaat
    53521 cttcctaaat tttgagttga gccccattca ttcgtagcat ttttaaaatc actattctta
    53581 atgaggttag ggccgcttac actatatttc ccaacctcaa cctgaaacag ttgattggtc
    53641 agagccatgc gagcaacctt atccgcaatt ccattttcag tattgcccaa aatccgctcg
    53701 taaagtttac tggtttcctt aacacgctgg aagtcagtag tctctacttt tcgcgctagt
    53761 tgattggtca cattcgcaaa ttgactatca gcattcgctt tgtttgcaga aacctgatca
    53821 gatattctac ccatttgtcg ttcagcatta tccttgtttg tagcgacctg agtctttaaa
    53881 tttgaaatct gattatctgt gccttgttta ttactgttta tccgatttga aatatttgaa
    53941 atctgagtag tggctccttg ctcactgctt gtaagtctat ttgatagacc actgatttga
    54001 ccgcccacat cttgcttata agtagttatc tgacttgaaa tatccgtgaa cttaccatct
    54061 acagattgac gatagctagc gatttgacta gcgatgtctt tattcgcact agttttaaca
    54121 gcttcaatcc tctgattgat acccttaaca tcttcttgat aagtaacctt accaacgaaa
    54181 tcacgattga ccagctcacg gactgctgtc gcttgtctcg tgctctcctc acgagtatag
    54241 cgctgtaggg cttcctgtcg ctgaccgttt ttatttacat attcctgaat agctgataaa
    54301 tcggttcgca agccctgagc tgtccgctca aaggtagcct tagcttcagt gatgagacca
    54361 tcagcgtcct caggcgcagg actccagtcc gtcgccacac taccgatttc aaccttgatt
    54421 cctgttaccc aagctgtacc gcttgtagca ccttcaagat tgaatcgcaa tgatgtcttc
    54481 aattgatcaa aatttgtttt ttcagagtag tcataagtga atgtaatata tttccaatct
    54541 gccgaacctt tatacatacc aagcgtagca taatctggac cactctgtac tccggtctca
    54601 ctattttttc taaaaagata atgtttgaag caattaaata cattccaaaa atttcgacct
    54661 tggactacat tttcgtactt gatccaagcg ctaaaagtaa ctttttggta caaccttgag
    54721 ctgaaatctg gttcaaggtt gaacgttaaa gtagagttgt tctctagcct atagcattct
    54781 ttttgacctg tgacgtggtt ttcaggtaat ttttcaatta cagctccaac cgtcttggat
    54841 tttatccata gattccggcc tcccaccttc atttttgaaa attcttcacg caatttccca
    54901 gcttcagata caactaaagt cttatctgct ttatccttgg ttgcgttcag gatttcctga
    54961 cggatagagc cagctcgcac ctcaaattca gcctgactca acttctgatt tagtttgttc
    55021 tgcgtgtctg tctcaagact cttcacagat tgccggatat tttcagcagt cacattgagt
    55081 gagctgatat cggctttggt tctaaggcct tcagtcagac ggcttacacc agcgtcgagt
    55141 gagttggctc gttgtttgaa ggtcgattca actgttgaaa tctgaccttc tatatcttca
    55201 ggagcttctg aataagaagt atctacatcg cttatttcaa acttcggcat ccaaatccaa
    55261 acggttcctt cctggttgaa attgaacaac cattcatttg tggtctgctt ggattcgttt
    55321 gtccaacctt ttggaatatg gacaacatat cgtttaattt ctgtcgacaa tgtcacattt
    55381 ccagttttat atccgatatt ccctaatcga gatcttagca ttattccatt tttatttgcc
    55441 ttagcataaa aactaatggt tacatcttga ttagtcgtac ttccgggaat tactttcccg
    55501 aattgaccca gagctgggta agtaaccttg ggattccctc catcacggcc agatggattc
    55561 agacctataa ttttaagagc cttatgtcca agatacttac tttcgctatc gatagcagcc
    55621 gtatatgtac tcgttgtcca aattcctgtt tttgaaatat cctgcttgaa tagtgagttc
    55681 aagaatagat ttcgaccgga tgcctgcaca ctcgcaatcc gactagccag ctcctcagct
    55741 gtctgcgtga gttctgactt gctggcttta tccttggttg cgttcaggat ttcctgatgg
    55801 atagagccag ctcgcacctc aaattcagcc tgactcaact tctgatttag cttgttctgc
    55861 gtgtctgtct caagactctt cacagattgc cggatattct cagcagtcac attgagtgag
    55921 ctgatatccg ctttagttct aagcccttca gtcagacggc ttacaccagc ttcgagcgag
    55981 ttggcacgct gtttgaaggt cgattcaact gttgaaatct gaccttctat atcttcagga
    56041 gcttcttttg agcttgttgc caaacttccg tcttccagct ggggcgcaag aacatctaaa
    56101 tattctccga cctcagcatt tacgagatac acatagccaa ttgatgcgac tccagcccta
    56161 tttctagcgc tagtaaacga tagctttgtc caattttcat cctttaatgt aaagatgggc
    56221 gaaatacccg aattatcatt gacttgccaa taagtttgta gcttgacctt ttgacctctt
    56281 ctgcctttga cccaacaaga catcgtgtat gtgccttgcg agatataaaa tccatcttga
    56341 gcaataccta tttggtctct agcattgctt gaggtcaatc gtatcgcttt atcaaagcca
    56401 gttgctggac tgtctgatac atcaatcgtc tttgccgtcc cagcgcctga cggtctaaaa
    56461 gtacctgatg cccacaatcc tctggctagc atcatgcgct ttgtaccccg gatataattc
    56521 ctacccccga cctgcacact cgctatccga ctagccagct cctcagctgt ttgcgtgagt
    56581 tctgacttgc tggctttacc attggccaag ttggtcagtt ctgaaagtct acgagtcgtc
    56641 gtctcctcat acgtcgcttg cgctgacttc
//
LOCUS       DBEJZV010000011        56451 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.11, whole genome shotgun sequence.
ACCESSION   DBEJZV010000011 DBEJZV010000000
VERSION     DBEJZV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 56451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.11"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(183..320)
                     /locus_tag="ACL3S0_000826"
                     /pseudo
     CDS             complement(183..320)
                     /locus_tag="ACL3S0_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(698..1387)
                     /gene="rplA"
                     /locus_tag="ACL3S0_000827"
     CDS             complement(698..1387)
                     /gene="rplA"
                     /locus_tag="ACL3S0_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGR1311772.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1595..2020)
                     /gene="rplK"
                     /locus_tag="ACL3S0_000828"
     CDS             complement(1595..2020)
                     /gene="rplK"
                     /locus_tag="ACL3S0_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGR1311773.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2329..3045)
                     /gene="ldcB"
                     /locus_tag="ACL3S0_000829"
     CDS             complement(2329..3045)
                     /gene="ldcB"
                     /locus_tag="ACL3S0_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGR1311774.1"
                     /translation="MKKRYLVLTTLLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKYYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3048..3518)
                     /locus_tag="ACL3S0_000830"
     CDS             complement(3048..3518)
                     /locus_tag="ACL3S0_000830"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR1311775.1"
                     /translation="MCLICQRIDLIKKEENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSLVQEAVAKAFTAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQVKPEEIKRLVECLSSEVDKLLEIKE"
     gene            complement(3520..4557)
                     /locus_tag="ACL3S0_000831"
     CDS             complement(3520..4557)
                     /locus_tag="ACL3S0_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGR1311776.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KNQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSGLVD"
     gene            complement(4655..5980)
                     /gene="brnQ"
                     /locus_tag="ACL3S0_000832"
     CDS             complement(4655..5980)
                     /gene="brnQ"
                     /locus_tag="ACL3S0_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGR1311777.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFVAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6151..6423)
                     /locus_tag="ACL3S0_000833"
                     /pseudo
     CDS             complement(6151..6423)
                     /locus_tag="ACL3S0_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(6630..7208)
                     /locus_tag="ACL3S0_000834"
     CDS             complement(6630..7208)
                     /locus_tag="ACL3S0_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGR1311778.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7262..8662)
                     /gene="pepV"
                     /locus_tag="ACL3S0_000835"
     CDS             complement(7262..8662)
                     /gene="pepV"
                     /locus_tag="ACL3S0_000835"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGR1311779.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8675..9280)
                     /locus_tag="ACL3S0_000836"
     CDS             complement(8675..9280)
                     /locus_tag="ACL3S0_000836"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGR1311780.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFACYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            9451..10251
                     /locus_tag="ACL3S0_000837"
     CDS             9451..10251
                     /locus_tag="ACL3S0_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1311781.1"
                     /translation="MKKFSLLLAILPFLVACENQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10433..11266)
                     /locus_tag="ACL3S0_000838"
     CDS             complement(10433..11266)
                     /locus_tag="ACL3S0_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR1311782.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDCVLEVLDGQYGLENPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11256..13100)
                     /gene="uvrC"
                     /locus_tag="ACL3S0_000839"
     CDS             complement(11256..13100)
                     /gene="uvrC"
                     /locus_tag="ACL3S0_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGR1311783.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPSI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13140..13841)
                     /locus_tag="ACL3S0_000840"
     CDS             complement(13140..13841)
                     /locus_tag="ACL3S0_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGR1311784.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13920..15152)
                     /gene="murN"
                     /locus_tag="ACL3S0_000841"
     CDS             complement(13920..15152)
                     /gene="murN"
                     /locus_tag="ACL3S0_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGR1311785.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15157..16377)
                     /gene="murM"
                     /locus_tag="ACL3S0_000842"
     CDS             complement(15157..16377)
                     /gene="murM"
                     /locus_tag="ACL3S0_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGR1311786.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16489..17268)
                     /locus_tag="ACL3S0_000843"
     CDS             complement(16489..17268)
                     /locus_tag="ACL3S0_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR1311787.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYMALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17337..18998)
                     /locus_tag="ACL3S0_000844"
     CDS             complement(17337..18998)
                     /locus_tag="ACL3S0_000844"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR1311788.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19173..21395)
                     /gene="recJ"
                     /locus_tag="ACL3S0_000845"
     CDS             complement(19173..21395)
                     /gene="recJ"
                     /locus_tag="ACL3S0_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGR1311789.1"
                     /translation="MITPTYEWQFALQVENADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIAFMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEVSFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMMDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21672..22431
                     /locus_tag="ACL3S0_000846"
                     /pseudo
     CDS             21672..22431
                     /locus_tag="ACL3S0_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22471..23235
                     /locus_tag="ACL3S0_000847"
     CDS             22471..23235
                     /locus_tag="ACL3S0_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGR1311790.1"
                     /translation="MISLFGLVAAKPVQANTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23248..23925
                     /locus_tag="ACL3S0_000848"
     CDS             23248..23925
                     /locus_tag="ACL3S0_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1311791.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23935..24594
                     /locus_tag="ACL3S0_000849"
     CDS             23935..24594
                     /locus_tag="ACL3S0_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1311792.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALVEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24852..26042
                     /locus_tag="ACL3S0_000850"
     CDS             24852..26042
                     /locus_tag="ACL3S0_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGR1311793.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTIKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26363..27244)
                     /locus_tag="ACL3S0_000851"
     CDS             complement(26363..27244)
                     /locus_tag="ACL3S0_000851"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGR1311794.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27385..28713)
                     /gene="vncS"
                     /locus_tag="ACL3S0_000852"
     CDS             complement(27385..28713)
                     /gene="vncS"
                     /locus_tag="ACL3S0_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGR1311795.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMYLDAQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(28710..29366)
                     /gene="vncR"
                     /locus_tag="ACL3S0_000853"
     CDS             complement(28710..29366)
                     /gene="vncR"
                     /locus_tag="ACL3S0_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGR1311796.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29415..29498)
                     /gene="pep27"
                     /locus_tag="ACL3S0_000854"
     CDS             complement(29415..29498)
                     /gene="pep27"
                     /locus_tag="ACL3S0_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGR1311797.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(29678..31057)
                     /gene="vex3"
                     /locus_tag="ACL3S0_000855"
     CDS             complement(29678..31057)
                     /gene="vex3"
                     /locus_tag="ACL3S0_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGR1311798.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31109..31756)
                     /gene="vex2"
                     /locus_tag="ACL3S0_000856"
     CDS             complement(31109..31756)
                     /gene="vex2"
                     /locus_tag="ACL3S0_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGR1311799.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31769..33046)
                     /locus_tag="ACL3S0_000857"
     CDS             complement(31769..33046)
                     /locus_tag="ACL3S0_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1311800.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKKMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(33403..33573)
                     /locus_tag="ACL3S0_000858"
                     /pseudo
     CDS             complement(33403..33573)
                     /locus_tag="ACL3S0_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(33716..34315)
                     /locus_tag="ACL3S0_000859"
     CDS             complement(33716..34315)
                     /locus_tag="ACL3S0_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311801.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNLSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNTK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(34452..35336)
                     /locus_tag="ACL3S0_000860"
     CDS             complement(34452..35336)
                     /locus_tag="ACL3S0_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1311802.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(35340..35726)
                     /locus_tag="ACL3S0_000861"
     CDS             complement(35340..35726)
                     /locus_tag="ACL3S0_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGR1311803.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(35719..37062)
                     /gene="cysS"
                     /locus_tag="ACL3S0_000862"
     CDS             complement(35719..37062)
                     /gene="cysS"
                     /locus_tag="ACL3S0_000862"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGR1311804.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(37149..38033)
                     /locus_tag="ACL3S0_000863"
     CDS             complement(37149..38033)
                     /locus_tag="ACL3S0_000863"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311805.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYQLAKLSNLEVLLADSSY
                     QEQISQLKFQAFSGEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(38045..38662)
                     /gene="cysE"
                     /locus_tag="ACL3S0_000864"
     CDS             complement(38045..38662)
                     /gene="cysE"
                     /locus_tag="ACL3S0_000864"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGR1311806.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(38678..40891)
                     /gene="pnp"
                     /locus_tag="ACL3S0_000865"
     CDS             complement(38678..40891)
                     /gene="pnp"
                     /locus_tag="ACL3S0_000865"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGR1311807.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(41578..42444)
                     /gene="metF"
                     /locus_tag="ACL3S0_000866"
     CDS             complement(41578..42444)
                     /gene="metF"
                     /locus_tag="ACL3S0_000866"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGR1311808.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(42508..44757)
                     /gene="metE"
                     /locus_tag="ACL3S0_000867"
     CDS             complement(42508..44757)
                     /gene="metE"
                     /locus_tag="ACL3S0_000867"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGR1311809.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVSAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLTVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEVILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(45018..45284)
                     /locus_tag="ACL3S0_000868"
     CDS             complement(45018..45284)
                     /locus_tag="ACL3S0_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1311810.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVPLEQGKS"
     gene            complement(45410..45813)
                     /locus_tag="ACL3S0_000869"
                     /pseudo
     CDS             complement(45410..45813)
                     /locus_tag="ACL3S0_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            45969..46970
                     /locus_tag="ACL3S0_000870"
     CDS             45969..46970
                     /locus_tag="ACL3S0_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR1311811.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(47143..49548)
                     /gene="pheT"
                     /locus_tag="ACL3S0_000871"
     CDS             complement(47143..49548)
                     /gene="pheT"
                     /locus_tag="ACL3S0_000871"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGR1311812.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIEFSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVSLLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(49625..50134)
                     /locus_tag="ACL3S0_000872"
     CDS             complement(49625..50134)
                     /locus_tag="ACL3S0_000872"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1311813.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(50134..51180)
                     /gene="pheS"
                     /locus_tag="ACL3S0_000873"
     CDS             complement(50134..51180)
                     /gene="pheS"
                     /locus_tag="ACL3S0_000873"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGR1311814.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHHHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(51772..53187)
                     /locus_tag="ACL3S0_000874"
     CDS             complement(51772..53187)
                     /locus_tag="ACL3S0_000874"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR1311815.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(53200..55038)
                     /locus_tag="ACL3S0_000875"
     CDS             complement(53200..55038)
                     /locus_tag="ACL3S0_000875"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGR1311816.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     MKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(55056..55895)
                     /gene="licT"
                     /locus_tag="ACL3S0_000876"
     CDS             complement(55056..55895)
                     /gene="licT"
                     /locus_tag="ACL3S0_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGR1311817.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
BASE COUNT        16197 a        12711 c        10357 g        17186 t
ORIGIN      
        1 gcacggcaag gcgacgttga cgtggtttga agagattttc gaagagtatt agaaagctcg
       61 atggactatt ccagattcat tccactagat ttcgaaatcg agtaggggat aatctctagc
      121 ccctctcaca ccaccgtacg tgccgttcgg catacggcgg ttcaactaac tgttaacgca
      181 tgtcattcaa ggtaataatc caaacacgaa accagtccac gtttttcaag gactggtttt
      241 gatatagcac gtttaagtac cgacttctga gctactaatt gatagtggtc gccccagcca
      301 gataccttat ccgctatata ggccttatta tcacgttcct gttcgtagag ccacgatttc
      361 gctatccctt cctctgacga ttcttatttc cagcgtcaga cttaaaacgg tctatcccca
      421 gaccgtttta atccgctacc tcacgatagt cagacttggg aatcgctatt gggttcaccg
      481 gtagcaggtg cccaccgagg acttacacct caaatatata ataaaatgaa ataagaatag
      541 gacgaatcga tcaggacagt caaatcaatt tctaacaatg ttttagaagt agatgtgtac
      601 tattctagtt tcaatctact atacaacatg cccgtcgtac atcaaaaaaa gttgagacat
      661 agcgtcttca acttttttac attactttaa ctactgatta aagtgagttt acatcaactt
      721 tgataccaac accttgagta gttgtgatag tcaagtttgt tacgtaagtt cctttagctg
      781 tagctggttt tgctttttgg attgtttcgt tgaaagcttt aaagttttca accaattttt
      841 cagcttcaaa tgatacttta ccgatgattg cttgaacgtt acctgcacgg tcagcacggt
      901 aagtgatttt accaccttta gactcttcaa ctgctttagc aacatccatt gttacagtac
      961 cagttttagg gtttggcatc aagttacgtg gtccaaggac acgtccaaga cgcccaacaa
     1021 gagccatcat atcaggtgta gcgataacta cgtcgaagtc caaccaaccg tcgttgattt
     1081 tagcaacaag gtcatcttca ccaacaaagt ctgcaccagc agcttttgct tcttcagctt
     1141 ttgcaccacg tgcgaaaaca agaacacgtg aagttttacc agtaccgttt ggcaatacca
     1201 ttgctccacg gatttgttgg tcagcttttt taacgtcgat gttcaagttg taagcaactt
     1261 ctacagttgc gtcaaatttt gcaaagttag tttcttttgc aagtgctaca gcttcttcta
     1321 cactgtatgc ttttgtgctg tcgattttct caagagcagc acgaagttgt ttgctttttt
     1381 tagccatttt ctattctcct tgtaagtggt tcaatcgatt ttcatctccc acgtcacttc
     1441 tcgaaatgat gaagtcttgc gggttttcag tctactattt ttctcttcct acggccttaa
     1501 gctcccttgc tgtacccaag tacaaggctc agtcacttgc ctagtatgaa aagcaactaa
     1561 tagactgctg tgagattttc tactgtgtta ttgattagtc aacaacagtg aatcccatag
     1621 aacgagcagt accttcgatc atacgcattg cagactctac gtttgctgcg ttcaaatctg
     1681 gcatcttagt ttctgcaatt tcttgtactt gtgcacgagt aactgtagca actttagttt
     1741 tattaggtgt acctgatcct ttttcaacac ctgcagcttt tttcaaaaga acagcagctg
     1801 gtggtgtttt cgtaacgaaa gtaaatgatt tgtcttcgta tactgagata acaactggaa
     1861 tgatcatacc agcttggtca gctgtacgag cgttgaactc ttttgtgaat cccatgatgt
     1921 tgataccagc ttgaccaaga gcaggtccaa ctggtggagc tggtgtagct ttaccagcag
     1981 ggatttgcaa ttttacaagt ttttcgactt ttttagccat ttttaaatcc tcctttgtgg
     2041 ttttggcggt aattaaagat ttttacctcc cacaagtatg ctttacacat acccatctat
     2101 tatacactat ttatctaaaa atgcaagaga aaagtttatt ttttgtactc aatgaaaatc
     2161 aaagagcaaa ctaggaagct agccgcaggc tgctcaaagt acagctttga ggttgcagat
     2221 aaaactgacg aagtcagctc aaaacactgt tttgaggttg tgaatagaac cgacgcagtc
     2281 agtaggtaag gcgacgctga cgtggtttga agagattttc gaagagtatt aatcgacgta
     2341 gtctccgcct tcaaagccat agtattcttc caaactgaga ccacttgcag caatttcttt
     2401 agcttctttt cctacataac gcaggtgcca ttcttcagcc atatagcctg tttccttttc
     2461 cttgcctttg agataacgga caacaaagcc ataatcagct gcatgatcca agagccattg
     2521 ggctgctttt tcttctgtca ccaaatcacc atcagtccca atcacatcaa aggccaagcc
     2581 tgtctggtgt tcgctatagc caggacgggc agagtaacgg tcagctgctg cctttccatc
     2641 ttggttgaca taatcttgat agagcttggt ctgagtttca taacttctaa aaccactgta
     2701 atgatcacta atagggaaac ctgcctcttg catcgctttg atgagtttga ccaactcagc
     2761 cttggctgtt ggattttccc cgggattata gtctttcgac aaaggataat atttattggc
     2821 tacgatgatt tcgtcgtatt ttccttggat gctgtagtaa tcacctttat tgaccacttc
     2881 tgcttttttc tgggcagccc cttgagactt actgccgact gtcccatcag ctttggctgt
     2941 ctgttctgtc ttagctgtgc catcttcatt ttttgctttt tcttgtgaac aagctgctag
     3001 actcaaggct agcaaggttg tcaagacaag gtatcttttt ttcatttcta ctcctttatt
     3061 tctaatagtt tatctacttc tgacgataaa cattcgacta atcttttaat ctcttccggt
     3121 tttacttggc aagtttctgc tgtcatttct tcaaagggaa cccaccaaac tggcccacga
     3181 cctttaagac cgtggccatt catatcacct gtccgtcgtg gaaacagatg ccaatgaaga
     3241 tgggcatcgc catttcctag cagttcgata ttcattttct cagcagtaaa ggccttggca
     3301 actgcctctt ggactagact catttcttcg agaaaacgga gtcttgtttc ctttttcaaa
     3361 tggtgcaatt cggtaacgtg ttccttagct agaaaaagac tatatcctgc aaaatactgg
     3421 tggtctccaa tcacaagata gcctgtttcc aactctttga caaagtaagg attttcttcc
     3481 ttcttgatga ggtcaattct ctggcaaatc aggcacatat tagtctacca acccactctt
     3541 aagataagca tcaaccatac gctctgttgc gaccaccgag tcaatatgag tacgctcata
     3601 agaatgacta gactcgatac ccgcaccaag aagagcgtgt ttaacttctg cacctgcaga
     3661 catagccgct gaagcgtccg aaccataaaa tggatagata tccagcttga atggaatatc
     3721 ttggttttta gccaaggtca ccaaatgttg acggaagtca tagtgataag gacctgaagc
     3781 atccttgaca cagatggaca ctgtgtactc atctgtttgc tgatcatccc ccatagctcc
     3841 catatccaca gccagatatt cgactacttg agcaggaata ttagaattag caccatgtcc
     3901 tacttcttca aaaactgaaa aagcaaaatg agttgttact ggcaattcaa tcttctcttt
     3961 cttataaata cgaagcaggt tgagcaaaat cgctgcgctg accttatcat ccaaatgacg
     4021 agacttgata aaacctgtat cagtcacaac agttcgtgga tcgaagctga taaaatcacc
     4081 gacctcaatc ccaagagcac gagtttcttt ttcattgctt acttttacat ccaaacgcac
     4141 ttccatattg tcctgcgtgc gctctgcagt tcctgcatcc ttgtagacat ggcaagaagt
     4201 ttggtggatg aggatggttc ctgatacctt ttgacctgtg ctagccacat gaacggtaca
     4261 gttttcacct tcaatcatgt tccaaggaaa accaccgata cggtccaatt taagacgacc
     4321 atctggtttg acagcacgaa caatagcacc cagcgtatcc acatgagcag tcacatagcg
     4381 atgttgctca tcattttgac ctttgatggt cacattgaca ccacccttag ctgtgcgaac
     4441 tggctggtaa ccaaaacctt ctagagtctt gactaaataa ttcgaaattt cacgagtaaa
     4501 gcccgttggc gatgcgatgg ctgtcagttc tttgatatat tctactgttt gattcatttc
     4561 ttcacctctt tcgctaccta ttataacaca tttatcatcg gataaaaaaa gaaaatcact
     4621 cctgtagact tggctacaaa agtgatttaa gtgattattc catttcaaaa acatcgcttt
     4681 cttgcttgtt tggtagaacc aatgagagca agattccaac aatggctggc accaaccatg
     4741 ggagagatgc cttggcaaaa ggaagaacgc taacaagatt tgcaagaaac tcaaccttaa
     4801 acgagcttcc tagtacgctt gcaatggcaa taactgtaac cacagcaatt gtcaactgca
     4861 tacctggttt tgaaagggca acaaatttgt tgacaatgac aatcataacg atagcaatcg
     4921 tgattgggta caagataacc agtactggaa ttgagtactt gataatcgca tcaagaccca
     4981 aattggcaat agcaaatcca atcaaggtaa aggctgtcgc ataaaccttg tagctgattt
     5041 gtgggaagcg ctcattaaag aactcagctg ttgacacaat caaaccaaca gtcgttgtga
     5101 agcaggttac ggtaaccata gctgcaagga agagttgagc tgttgagcca aagatttctt
     5161 gagtggcttg tgacaagatg taaacacctg gtgttccacc cttcatcgct tcagctggta
     5221 ctgggaaatg atttccaaga aaacctaaac cgatgtaaag agcgctgaag gcaagggcaa
     5281 caacgatacc aacaacccaa atagttgaaa tgtattcttt cttacttgaa aatccaagtt
     5341 gtttcaaggt ttgaactgcg attacgctaa aggccactga ggcaagggcg tccaaggtat
     5401 tgtaaccttc taggaaacct gtaccaaagg cagaagcttg ataagcagct gaagcagctt
     5461 gaggacttgt tccaccatat ttgatagctc ccagaacgac caagataaca atcaaaattg
     5521 caaagactgg cgttaaaata cgtccaatgc ggtctaagat ttttgatgga ttaagcgaaa
     5581 tcaaataggc tgccacaaaa tacagaaccg taaatacaat caagccaagt cctttatttg
     5641 catccgacaa aagggggcta atccctactt cgtaagctgt tgtagcagta cgtggggtag
     5701 caaagaatgg accgattgac aagtaaagaa ctgagaggta aagagtcgca aaccaaggcg
     5761 ctatcttcgt tgaaatctcg tagatatatc ctttaggatt tagcgttcca ataataaggg
     5821 tcaagacggc gataccaacg cctgaaaaga caaaacctgc gatggcagga agaaaatgtt
     5881 ctccagatag agcacctaga gaaggcggaa aaatcaagtt ccccgcacca aaaaatattc
     5941 caaacaggag caaacctgtt agggtacctt ttttagccat aaaaatctcc ttcatattta
     6001 taaaatactg acctagtata ccacgattag gagtctgaaa aaagcatcac gaggcaaata
     6061 ttaaatgttt tcaattttct taaaaataag aattatctaa aaataaaact ctcctaccca
     6121 gtccacacca agtaggagaa atgcaaaatt ttaaagttct tcaaaggcta acatgccacc
     6181 ctggacattg ataacattat aaccttgttc taacaggaat tggcaagcac gcgccgatct
     6241 cattccagat ttgcaaataa tataatgcaa gcgatctttg tccaattaat cataactatc
     6301 agccaattga ctaagcggta ggttgtgggc acattctaaa tgaagagctg caaactcatc
     6361 cactagagaa agctggtcgt tttggtaaag ctggtaaaat gcgtcaaagg ctatttcttt
     6421 cattcttttt cttctaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac
     6481 cgtgcgtata tgtaactgac ttcgtcagtt ttatctgcaa cctcaaagca gtgctttgag
     6541 ctgacttcgt cagttccatc cacaacctca aagctgtact ttgagcagcc tacgactagc
     6601 ttcctagttt gctctttgat tttcattgac tataaaatgg ttttaattct ttttttcaaa
     6661 tctggcacta cttctgcctc aaaccaagga tttttggcca tccagatttg atttcgtggt
     6721 gatgggtgaa ctagcggaaa ataggctggc agatagtctt tatagtgttt caccctctcc
     6781 gttaccttcc cactgatttt ctcctgtaaa tagtaggctt gggcatattg cccaatcaag
     6841 agggttaact gaatatcagg caattcctgt aagagctgcg gatgccattt ttctgcaaaa
     6901 cctgtacgag gcggaagatc acccgacttg ccatgtcctg gaaagtagaa atccataggc
     6961 aaaacagcaa aataacctga attgtaaaag gtatcttcat ccacacctag ccagtcccgc
     7021 aagcggtcac cacttttatc tttccagtaa aggcctgctt cttgagtttt aagtcccgga
     7081 gcctgaccga tgatattgat gcgagcagtt tttggcgctg caaagagagg ctcaatgcca
     7141 cgctctgtat agctggcatt ctgtgaatcc gccatgatag cctgtttgat tctttcgatt
     7201 tgagacatct actttccctc caaaaagaag tccaagcata agatctcaga cttctatcgt
     7261 tttatttgat caattcgtaa atagcttcgg cataaattgc tgctgctcgg aaaagatcat
     7321 ccaaggcgat aaattcattg gcttggtgca tggtatcaat cgagtctggg aacatagcac
     7381 cgtaggcaac tccgcgttct agcaagcgac caaaggttcc accaccgatg acttgttcat
     7441 gacctttaag gccagtttgt ttttcataga tattcaacaa ggtttgcaca agtggatctt
     7501 ccattggcac atagtgaggc gtgtgaccgt gttcagacag gctaacagaa acaactggca
     7561 agttttcaag gattgacttg atttgttctg gacttgttcc ttttggatag cggatgttga
     7621 gggcaatggt attatcagca cttgtttcat cgaagcggaa gacgccggca ttcatagaaa
     7681 gagcacccat cttttcatcc acatgagcaa tcttaagatt ttcaccctca tgatcgttca
     7741 agagaatttt acctgcgatg tcaaggtagt ctttggctgg accagcaaag ccaaactggc
     7801 tgaggaagag ggcaaggtaa gttgcgccat tgacacctga agcaggcata gcaccgtggg
     7861 ctgatttacc aatgatcgtc accttgtatt tgccagcttc ttcttggagt tctcctctaa
     7921 gtttgtgttc tgcaacaaag gcatctagtt tagcttgcaa gtcagccaag tcacctgaaa
     7981 cgactgctgt tgctgattct ggtaccatat tttcacgtaa accacctgta aagctgtgaa
     8041 gacgggcaac acctgtattt tctcctgcaa agtggaggta ttccgtgata tttccttttt
     8101 caccattgat gattggaaat tcagcatctg gtgagaaacc gaaatctggt ttggcaagtc
     8161 ctacgtgctc aaagtagtag tccatgtctg cccagcctga ttcttcgtct gttccaacga
     8221 tgaagcgaac tttcttagaa gttggaagac ccaattcttt gatgattttc aaaccatagt
     8281 aacaagctgt tgtaggaccc ttatcgtccg aagccccgcg cgcataaagg cgaccatctt
     8341 tgatagttgg tgtgtaaggg tctgtgtccc aaccgctacc agcaggcacc acatccatat
     8401 gggcaaagat tccgagaact tcttctccat caccaaactc aaaatgtcct gcatagttat
     8461 caacattctt agttgggtag ccatcgcggt ctgcgatttc aaggaatttc tccaaggctt
     8521 ttactggacc aggcccaaat ggatgctggg catcagcctt gctgtcatca cgttctgaat
     8581 tgatttccaa aaggctaaac aagtcagcca agaggtcttc tttgcgtttt tctacttctg
     8641 ctgtaaaatc aattgctatc attttttctt cttcctatct tttttcgatg atttcatcta
     8701 ctggcaagcg gtagcttggt tccaatttgt cgtctgtata acccactgtg atcaagagtt
     8761 ctgggcggaa acggtcttcg atttccaaaa cttcattaac ttttgatttg tcaaaaccaa
     8821 gaataatgtt agaaccaatt ccttggtctg tcaatgcaag aaccaagttc atggcaacca
     8881 aacctgcatt gagagctagg tagtcgctga cttgttgctc actgtaacag gcaaactcag
     8941 ctggcagatt tttcataaaa tattgaagtt gctcttcaga aaagttatta gcaccaccaa
     9001 cacgggcaat cttacgagca cgtttggcta agtccgtatc tgtaaacaag gcaatggtta
     9061 caggcgctga tgatacctgt tcaaaattgg aaccataagc taactttgcc agttcagcat
     9121 ttttctcacg taccaccaca aatttccaag gctggctgtt gtgggcgctt ggcgccaagg
     9181 ttgcaatttc gatagccgta cgcacatctt tgggatcaac aggcttatca gtaaaatgct
     9241 tagtcgcatg acgtttttta tttaattcaa gaaatttcat aatcgatttc cttttctaat
     9301 tctactgctt ccattctacc ataatttgaa agagcttgca gggttttttc atgattaagt
     9361 ttttctatca cagacataaa agatatatat tggtttatca ggaaagtttc tgataaacta
     9421 gcaagtactt tacatttgaa tggagacagt atgaaaaaat ttagcctatt actagctatc
     9481 ctaccatttt tggttgcctg tgagaatcaa gctacaccca aagagactag cgctcaaaag
     9541 acaatcgtcc ttgctacagc tggcgacgtg ccaccatttg actacgaaga caagggcaat
     9601 ctgacaggct tcgatatcga agttttaaag gcagtagatg aaaaactcag cgactacgag
     9661 attcaattcc aaagaaccgc ctgggagagc atcttcccag gacttgattc tggtcactat
     9721 caggctgcgg ccaataactt gagttacaca aaagagcgtg ctgaaaaata cctttactcg
     9781 cttccaattt ccaacaatcc cctcgtcctt gtcagcaaca agaaaaatcc tttgacttct
     9841 cttgaccaga tcgctggtaa aacaactcaa gaggataccg gaacttctaa cgctcaattc
     9901 atcaataact ggaatcagaa acacactgat aatcccgcta caattaattt ttctggtgag
     9961 gatattggta aacgaatcct agaccttgct aacggagagt ttgatttcct agtttttgac
    10021 aaggtatccg ttcaaaagat tatcaaggac cgtggtttag acctctcagt cgttgattta
    10081 ccttctgcag atagccccag caattatatc attttctcaa gcgaccaaaa agagtttaaa
    10141 gagcaatttg ataaagcgct caaagaactc tatcaagacg gaacccttga aaaactcagc
    10201 aatacctatc taggtggttc ttacctccca gatcaatctc agttacaata acactcttcg
    10261 aaaatctctt caaaccacgt cagctttatc tgcaacctca aagctgtgct ttgagcaacc
    10321 tacggctagc ttcctagttt gctctttgat tttcattgag tataagatat actaaaagcg
    10381 attggaccag ccaatcgctt ttttagtttg cattggctat tttaggaaac tcttacaaaa
    10441 aatcaaaaaa attcttcaca tcctctacat acccatgctt ttctattaag ctggctaaaa
    10501 gttccagatt gtgcccctga tagttatcgt cacgacgcag ttcttcatac atttcaataa
    10561 agggaagccc cttggacttg gccaattcta actcagcctc gtaatcataa gcaactttac
    10621 gaaattggat attgaccaat tccccatctt caacttctat cacggcatac tgggcacggt
    10681 gattttttaa cgcctcccaa ttaaaatagg gcatgccaat cgaccctgga ttgatgattt
    10741 gttgcccttg acttccataa cgaagcaact gcttgtgaac atgaccataa actgccacgt
    10801 ccgtttccgc atctagcagt tggtcaaatt tctctgtatc attctcaact agcaagtcac
    10861 caccatagtt cttatttggc aaattatgag agatagaaaa gcgcagtcca gcaatttctt
    10921 tcttttccag caaaggcaag cttcgtagcc agacagtcgt tgcaggatcc attcgctcca
    10981 tcaaaaactg agtcattcgc atgagctgga tttcttgcgg attttccaaa ccgtattgcc
    11041 catccaagac ctccaggaca caatcatccc aattgcctcg aacactggct gtgataggaa
    11101 ggtcctttag cagggcgact aagtcatttg cgcctggacc aggaagaaaa atatctccca
    11161 gaagccaata ttcactggcc ccttgatttt tagcatctgc aatcactgct tctagcgccg
    11221 tcgcattgcc atgaacatct gataaaattg cgattttatg gttcattgtg gtttccttcc
    11281 gtttggtaat ctactctttc ttctgctact tgaggcaagg cttctccctg cgggttcaac
    11341 tttctttgca cagcctctgc tactgctctt ggtactccaa cttcgacaat ctcatccaca
    11401 ctggcttcct tgattttggt cagagacttg aagtgcctca tgagattttg cttgcgttta
    11461 ggtcccagac catcaatccc atccaattga gatgagaaag aatttttgga gcgcagttgg
    11521 cggtggaagg taatggcaaa gcggtgcacc tcatcttgga tgcgttggag gaggaaaaat
    11581 tcctgagaat tgcgagacaa gtccaccacc tcaagcggat ctccaaagag cagttcatgg
    11641 gtttggtgct tatcattctt ttgcagccca gcaattggaa tatccaagcc cagttcctct
    11701 tggataacct gcttagcgat attgacttga ccttgccccc catcaatcac aatcaaatct
    11761 ggaggagtca aagcctcacg ctgtactcga ccatagcgtc tgcgaatgac ctctctcatg
    11821 ctggcatagt cgtctggtcc aacaaccgtt tttatcttgt acttgcggta atccttctta
    11881 ctcggtttac cgttgacaaa gaccaccata gccgaaacag ggctagttcc catgatatta
    11941 gagttatcga aggactcgat acgtactggg gtcgggattt ggagcaaacg tcctagattt
    12001 tcaatagctc cttgggtctt ctcgacagat ttctctagca ggttaaattt ctgctccaga
    12061 ctaacacgtg cattttttat ggctagattg accagctgtt ttttctctcc acgttggggt
    12121 ttgagaatct tggtatccac caaagccttg acagcttctt cgtcaatatc ctgcggaatc
    12181 agtacctcat tgggaactag gtgagatttt tcttgataga attgtcctac ataggtcaaa
    12241 aaatcctcat ctggatcatt gaagtagggg aagagattga catcgcgctc gatgagctta
    12301 ccctgacgga caaagaaaac ctgcacacac atccagccct tatccacata gtagccaaag
    12361 acatcgcgat tttggagatc cttagccatg acccgttgct tggttcgaag cgttccaata
    12421 gcctgaatca ggtcacggta ttccgccgca cgttcaaact ccatagtctg ggctgccgct
    12481 gccattttgc cctttagctc atcaatgatt ttgttatcct gccctttcag aaaatcagaa
    12541 acctcctggg ccatagactt gaaataagtc tcatccttct tacagatggt gtgggccatg
    12601 cattgaccga tatggtaata aaaacagacc ttagagggcg ggttggtaca cttacgaaaa
    12661 gggaatatcc gatccagcaa ccgcttgatt tcattggccg cccccacatc gggatagggt
    12721 ccaaaataaa gacctccgtc ctttttgacc tgacgagtga taatcaagcg tggatagcgc
    12781 tcattggtga ttttgatgga aggataggac ttgtcatcct tgagcatgat attgtacttg
    12841 ggcttgtttt ccttgatcag gttgatttct aggagaagtg cctcaatatt agactccgta
    12901 acaataaatt caaaatccac aatttcagac accagagcct ctgtcttggt atcatgactt
    12961 ccacgaaaat aggaccgtac tcgattacgc agatttttag cctttcctac atagataatg
    13021 gtgccatttt tatccttatg aatgtagcaa ccagggctgg tcggcaagag ctctagtttt
    13081 gatttaatca agttgttcat agttccatta tagcaaaaaa agtagggaaa gatagtaccc
    13141 tactcactag tctcatatat ttttcggagg tttgcaacat cctcttcctg gataccataa
    13201 aaggaacctg ctggttgcat gacagacttc tcatctgtat ggtccaagcc aatcgcatga
    13261 cctaactcat gttctgccgt atggacaagg cgttcatagg agtagccata gtatggattg
    13321 gacaaataat aatgattcaa ccgcaccgtt acggacaaga attgccctgt taagagatta
    13381 gtttgacttt ccgcctctcc tgccacagga gtgcctccgt cgttcatctc cgtagccgta
    13441 atatccgcct tactagactc agtcacgagt tcaaagttaa aagcaccagt ttgattccag
    13501 ttctggattg cttctaaata agcctcttga aagcgtgaat ccatctgcgg atccaggtaa
    13561 atacgagcag aggcctgtgc ccaccttcct tcagaatgct ggtgactatc tgtctggctt
    13621 aacttaggca gttgccctgt tttctcccat tggtcaatac tttgttgacc aatttttact
    13681 gaccgttctg cttgctttag cgctccttga aaatctccgt tcagatacca gagaagtccg
    13741 aaagcaagca cacataagag cacaactatc caaaccagac gccaaaacaa acgccacaca
    13801 aaagaaaaga aagcccctat caaacgaaaa agccagcgca tgtctctcca cctttctagc
    13861 aaataagaat tattttacta aaagaagcta aaagaaatct aaatactgac tttttcatct
    13921 taacgtccta ctattttttt gagtaactgg atagctttgt attttaaagg cgatggatgg
    13981 taacggaaag tacccgcttt gcgtacaata tagccattaa aattctgttt aaaacgcaaa
    14041 acaccatcac ttccatcaaa aatcccttga atgcctagga aattgtattt aggtattcca
    14101 cgttttatgc tttccaacat aacatatttt tgaagcagtg caggggcata gaacttatta
    14161 aactcagtgt aggaaccact aaagagataa gtcgtttcct gaggcatata aacaaataaa
    14221 ctcccagcta aaacaatatc ttcttctcca tatttttcaa tcaagtctcg cgcttctgct
    14281 tttcgaactt caaacgtttc aaattgacta gaatattctc tcagttgatt ttgttttttc
    14341 tcagaatgag gatttttact caaatcaagt cgcaacttgt ccaagttttc ttctagttta
    14401 ctttgttcac cttgcaattt gctcatatac tccgaaaaat tcaagcttgc tatgagaaac
    14461 tccgcttgtt ctccaaaagt atcataaaaa tgctcataat attctaaact tttatcacta
    14521 tattctctac gttcagaggt ttcttttgtt atattcttaa aaatcgatag ttcttcacgt
    14581 tttaactttt tcaaccgaat gccaaaggtt tcagcctttt tcaccaaggg tttacccttt
    14641 ttgctaaaac ttttaagcaa actcttttca gttaattcag ttaaatcttt atagtataac
    14701 caatctggtt ctccacctgg gtaacctgtt gtcaagccat caaattgata acctaaatca
    14761 gtcaaacctt gaataatact ttttttctca gcatctattg gattaccttg gctatcaaaa
    14821 gtttgataag tttcataggg ttttacaagc aactctaata caccattttg cttggcatat
    14881 tcttttaact ctgcataaaa aactggaaga gcatcttgtt gggtataaat cggccccgaa
    14941 ttgagttcca tatgcagacc acccagcatg ggcaggctat aaaccagagc tgcaacttga
    15001 atttctcctt cttgtttcaa agcaagataa acaattcgag cccctctttt ttctagcaaa
    15061 tcccccatct ggacagattg cataaaggaa cgagaagaaa cctgatcaga ataagtctga
    15121 aactcttctt tcgtgagtgt tgttagtgcc atatacttac tttctatgtt tttttcttaa
    15181 tgttttacgg aaatcaagag caagtcttaa cagaggatag agaggatgag tgggcattgt
    15241 aaattcaccc aagtattctt caatcgttgg attaaatttt tccttaaaat gataaagtcc
    15301 accattgaga gagttttcaa caccacctaa attttgccag atcatacctc gttcaaaggc
    15361 atagcgagcc gtttcatacc aagttaaaat tggtgcattg taacgtttaa aatcatcatc
    15421 cataccagca tatatattga cagaggtagt accaaattcc aaactcaaag tagccgctaa
    15481 aggaactctc gcttgaccta catctatata ttcctgcaag aaggtcaatt cctctaacaa
    15541 acgttctttt tccttcttct gcgcttctac ttttgaagtt cgagtcgact cagtaaaggt
    15601 ctcttccaag gctctatttt tcgctaactg ttcttctaac tcttgcgaac gtttagaaac
    15661 atccaaggtg gccaaggtga tataggcctt gtccttaaaa ttatctaaca attttttata
    15721 ataggcttca ttcctcaaat gaatctcttt tcgcttctca gtttttttca tcaactccga
    15781 aaatgaatct aatagttcca gtccaccata ttgaatctca agccctttgt ttcgtgctgt
    15841 tcgaatagcc tgttttgttg acttggaaag tttatcttct tcaaaatttt ccttgtatat
    15901 tttcgcctga atacgaggtt gaatggtgtc tcccatttcc tccgtttttc ctgaccacct
    15961 tactcccatt tgttgcaaac tatcaataat agccagattt tcaggaaatt ctgtcttttc
    16021 ctgattgatt aaactttgag ataggcaaat acttgggtca aaagtcacaa aaaccgctct
    16081 cttactgcga gcataggact taatagactg aatggcaaaa ttcaagagtt ctttatcccc
    16141 ataatccaat ataggtcctc ttgggatgta aaacatttta tagcctagcg gaagagttct
    16201 aatcaaaata ctagctgtcg ccagtaattt ttcttccctg taaacaccaa acttctcatg
    16261 ttgccaatta gacttaactt cctcccaagc actactttgt aatacattgg ctaattcatg
    16321 ttctttgaca aactgatcat attctaatgt gggaatgcca atttgataac ggtacatttc
    16381 ctactctctt tcctccagta ttttattact attctactac tttcgtttga aaagtctagt
    16441 gaaaacatat tttattttag ttctactccc cctatgctga agttcaaact aagtcagtct
    16501 ctcttctaat ttgaaatcaa ttggtagggt tgttaaaaaa acttccaatt gtttttccca
    16561 gtagtaccac tcgtgagttc cagcgctatg gctataggtc acatcaaaac ctagtttttt
    16621 gagatttttc actgcgagat tattggcttc gtacaagaaa tcctgttcgc cacaccacgc
    16681 ccaaagtttg gtctttttat ccgatttttt agccagactt tcaagagaat agggactagt
    16741 tgtccagtct ctaatctctc caaaaacacc tctccagtag gctggacttc ccagattttg
    16801 actttcagga gaaaagtttt gaaagctgag ggcacctgaa aaactagctg catgagaaaa
    16861 acgatttgtc gtaagagcca gtttgaagca gccgtagcct cccatagaaa gaccagcgat
    16921 aaaggtcttt tcacgcttgc tagtcatatt agggaagaag cgtttcagaa cctgtggcaa
    16981 ttcctctgct agagccatgt agtagtcaaa accatactgg gtatcggtgt accaaccatt
    17041 gctggtattg ggcataacaa cgatgagatt agttcctcga agcaagcgtt ctacattggt
    17101 ccgcttaagc caactattat gatttccaga catcccgtgc aaaaggtaca agacgggaat
    17161 atcttcacac tctggttctt ccactcgatt ggcatcaggg tagaggacat tcacccccca
    17221 ctccatatcc aatacttgtg agtaatactc gattttcatt actgccatga ttttctcctt
    17281 ctatttttct ataagaaaaa gccgaaactc gactttctct ctgtttattt caacgattat
    17341 tttgcttcca tgactactgg taaaatagct ggacgacgct tggtttggtc aaagagatac
    17401 ttggtcaaat tatctcgaac cttcccttta agatctgccc agtcaaagtc atctccttga
    17461 agatactctt ctaccgtttg gttaatcaat tctgaacttt cacggagaat atcgcgactc
    17521 ttcttgagat aaacaaatcc gcgcgtatga acacgagccc tagccacaat tttcttctca
    17581 cgacggttga ctgtaatagc cacgatgaaa attccatcct ctgacaagac cttacggtca
    17641 cgaagaacaa catttccaac atcaccaatg gcattcccat caatcaagat atctcctgct
    17701 gaaaccgatc cagctggaac aaagtctcca ttctcgtaag ccatggtcgt ccccttttta
    17761 ggaatgaaga tgcgttctgg caacatccca actgccatgg cagccttagc gtgagcatcc
    17821 aactcacgat actccccttg gacagggaag aggtacttag gttgcaaaag attgatcatc
    17881 agctgcaaat cacgcacatt tccgtgccct gatacatgta aactttgggt aatcaatttg
    17941 acaaccccac ctgcctgata aatcatattt tccacacgcg caacaaaggc ttctttagca
    18001 atagacggag ccgtagcaat atagaccagg tccccatcct tgatttctac ataacgatgg
    18061 cgaccaatcg acatcttacg aagtccattg ataggttcac ccatacgacc tgtctcaaga
    18121 ataatcaact catggtcttc aaagcgagac atatctttag gcttaatcaa gagaatttcg
    18181 ttggctaaag acaacttctt aagacgaatc gctgtgcgga cgatattttc aatatcaaat
    18241 cctgtcaaga cgatacgtcg acctgtttta tccgcagcgt caaaaatctg ctgaatacga
    18301 gaaagattac tggaaacagc tgcaacgatg atacgacctt cccagtcagc aatagtttgg
    18361 gtaatttcat ccctaacttc actttcacta gccacctgaa tattgctgtc tgcattggcc
    18421 gaatcactga ggagagccag gacgccgtca cgaccaatct ctgccaaacg agcaaaatca
    18481 gttgcataag attcactagc cgtttggtca aatttgaagt cacctgtata aacgatgctt
    18541 ccttccgatg tcttcaagac aattcccaga ctctctggaa cggagtaagt cgtagggaag
    18601 aaggaaacca ctgtcccacc aaaatcaatc tccgtattct catcaatgac atggaaatca
    18661 ttaaatttct taacggcatc atttcctttg acaaagagct ttgccaactc aatggtcaac
    18721 tcagacccaa atacaggaac tttagcctct gccaagagat aaggtagagc accaatggca
    18781 tccgcatgcc cgtgggtcaa gaaaacccca gcaatacggt cgctattttc aaaaaggtaa
    18841 tccatgtttg gaatcaccac atcgacccct aattgttcat tttcaggata ttttaaccct
    18901 acattcaaaa caaaaatgga ctctccaatt tcagcaatgt acatattttt tccattctca
    18961 cgcacaccac caagtgttgt taaactgata ttactcattt ttcctccaaa atcttagttt
    19021 atcttgatta tagggcaact ctaccctctt attctaaaag ttctaatact ttcagccgaa
    19081 tcttttccta ccattatacc atttttttga tgattttcaa aatgaaggtc tgttttcaaa
    19141 aaagagttga tttcccaact ctttcctaac ttctactctt tttccatcaa aaaatcataa
    19201 atttcttgca ccgtacccag cgccatcatt tcttggtctt taacggtttg tttgagattt
    19261 tggtaaattt gactttctcc tatctcccgc tttggcgcct ctttattgac tgtcatcaca
    19321 ccatctttta tcgtcacaaa gcctagttct tcaaatactt gaatcatctt gaccagcaag
    19381 atttgttgaa tattaagata tgcagccaaa tctttcagct tgtagcgaat atcaaactct
    19441 gggaactggt aaatagtctt gtacaatttg gcaaactgat ctctagtccc ataacctgtc
    19501 agataatagg ccttgtcaat atcatttttg aaatagacag cagagaaatg ctgttcctga
    19561 aaaatggtct tcagctgagt aatatcctct ggaatgtttt ttacgacaac agcttcacta
    19621 gccgcaagat ttggcagttc tccaggaaaa tccaagactg gaacaccttc tggcaagact
    19681 gcattttttc cacgaatgtt aaaaagttga acaccttcca ctcgcgcatc catcatcatc
    19741 aactggaggg cagtttggcc gttccattgg ttgacagaca atttaaccgc taactctaga
    19801 ttcttggttt gagaaaactc tgtcgcccat ctgccttgac caaaggctac cacttcaaaa
    19861 ctcacctcac ccttggaaat tttcagcttt agatgggcat tacctgcccc catagtacga
    19921 gcactttcga cctgaaaatt cttgatataa aaaataggtt tctgattatc cattccaaaa
    19981 ggagctaaac gttcaaaact tttgaccgtt tccaagctaa gtgcctccaa atccaactct
    20041 tcatctaggt ttaacttatt cttgccacca gcatctgcac ctttttcacg aacataatct
    20101 tccaaaacct gagataaatc tgagagttgc tcaacttcca gcgtcatacc cgctgcacct
    20161 gcatgacctc caaaggcgat aaagaggtct cgatggggat ccagagcttc aaaaatatcg
    20221 accgcttcca cactacgagc actgcccttg gcacgaccgt cttctatatt aagaacaatg
    20281 actgtctgtc ccaattcttc caataaacga ccagccacga ttcctagaac cccaggattc
    20341 cagccttcct tggccaagac ctgaaccttc ttctcaggat ccaccatggt cttggcttct
    20401 tcatagatag actgaacgat ttccttgcgc tcttcgtttt tctggtgaat cataaaggca
    20461 atctcatgcg cttcctcatc atcaaatcca gtcaacaaat caatggcagg attgggatca
    20521 tccaagcgac ccaaggcatt caaacgagga gcaatctgga aaccaaccgt ttcttctgtt
    20581 acttcgttgg cagcaatccc agccatgtcc agcatttctt gcagaccaat gcgctgggta
    20641 tgacccaaca tttccagacc atattgaact aagatacgat tttcatccgt cagactcacc
    20701 atatctgcaa tagttccaat agcgaccaaa tcaagcaatt ccacttgcac ttcttctaac
    20761 agggcacaag ccaacttgaa agcaactcca caaccagcca aatatttaaa aggataatcc
    20821 gcatctggat gttcaggatg gacaatagca taagcatctg gcagggtttc aggcatggaa
    20881 tgatggtctg tcacaatgac atctactccc atagactgag ccaatgcaat agcctcatga
    20941 ccagcaaccc cattgtccac cgtcacaatc aaggaaattc cttcttgctc gataaagtat
    21001 ttataaacac tagcattagg gccatagcca tcggtaaaac gatttggcag gtaaactcgg
    21061 cactcagcac caagttgttc caaactttcc ttcacaatag aagccgaagt catgccatcc
    21121 gcatcatagt ctccataaac gagaatattt tccccttctt caatagcctg acgaatccgc
    21181 tccactgcct tgtccatatc atggagcaga taagcatcat gtaagtcctc caaggaaggt
    21241 tctaaaaact tcttcagact ttcttggtcc tgaatccctc tctcaaacaa taaccgagcc
    21301 acctcaggac ccagtccagc cttcttggct atctttgtaa aatccgcatt ttctacctgc
    21361 agggcaaact gccattcata agtaggtgtt atcaaaaaga catccactct ttctaagaat
    21421 tctattgctt cattataaca tgatttagac gttttctcta tccagattgc ttttttataa
    21481 cattttatag tatattgaaa ctagaatagt acacctctac ttctaaaata ttgttagaaa
    21541 tcgatttgat tgtcccgatc gatttttcct gttcttatat cactatagtg aattttttca
    21601 gatatgattt gacaagaaca ttcttttatc gtagaatcat gctataaaat ctaacacaag
    21661 ggagatctct catggcttta gtagaattta aaaacgtcga aaaatattac ggagactacc
    21721 acgcactccg caacatcaat ctccgttttg aaaaaaggac aagttgttgt cctgcttgga
    21781 ccttctggct ctgggaagtc cactcttatc cgtacgatca atggtttaga ggctgttgac
    21841 aaaggaagtc tcctagtcaa tgggcaccaa gttgctggtg ccagccagaa agatttggta
    21901 cctcttcgca aggaagtcgg catagttttt caacatttta acctttatcc acacaaaaca
    21961 gtgttagaaa acgtaacact tgcacccatt gaagttctag gaattgataa aaaagaagct
    22021 gaaaaaaccg cccaaaaata tctggaattt gtaaatatgt gggacaagaa agattcctat
    22081 cccgccatgc tatctggtgg acaaaaacag cggatcgcca tcgctcgtgg tcttgctatg
    22141 catccggaac tcctcctctt tgatgaacca acatctgctc ttgatcctga gactatcgga
    22201 gatgttctag cagttatgca gaaactggcg catgatggga tgaacatgat catcgttacc
    22261 cacgaaatgg gctttgctcg agaggttgcg gaccgcatta tctttatggc cgacggagaa
    22321 gttttagtag atatgacaga tgtcgatagc ttttttgaca atccaagcga acctcgtgcc
    22381 caacaattcc tcagcaaaat tatcaaccac gaaagtgaca aagtcaaata aggaggcgcc
    22441 tatgaaaaaa aattcttttt atcagcatta ttgattagcc ttttcggcct tgttgctgcc
    22501 aaaccagtcc aggctaatac tagtatcgca gacattcaaa aaagaggcga actggttgtc
    22561 ggcgtcaaac aagacgttcc caattttggt tacaaagatc ccaagaccgg tacttattct
    22621 ggtatcgaaa ccgacttggc caagatggta gctgatgaac tcaaggtcaa gattcgctat
    22681 gtgccggtta cagcacaaac ccgcggcccc cttctagaca atgaacaggt cgatatggat
    22741 atcgcgacct ttaccatcac ggacgaacgc aaaaaactct acaactttac cagtccctac
    22801 tacacagacg cttctggatt tttggtcaat aaatctgcca aaatcaaaaa gattgaggac
    22861 ctaaacggca aaaccatcgg agtcgcccaa ggttctatca cccaacgcct aattactgaa
    22921 ctgggtaaaa agaaaggtct gaagtttaaa ttcgtcgaac ttggttccta tccagaattg
    22981 attacttccc tgcacgctca tcgtatcgat gccttttccg ttgaccgctc tattctatct
    23041 ggctacacta ataaacggac agcactacta gatgatagtt tcaagccatc tgactacggt
    23101 attgttacca agaaatcaaa tacagagctc aacgactatc ttgataactt ggttactaaa
    23161 tggagcaagg atggtagttt gcagaaactt tatgaccgtt acaagctcaa accatctagt
    23221 cataccgcag attaaggagg ataccctatg acagatttat catcttggac agcctatttt
    23281 caggattttg gacaattttt caatggtttc ctctttactc ttgccctagc gattggatcc
    23341 tttatcctcg ccatggtctt aggaatcttc tttggtgcca tgtcaaccag taaacgtcca
    23401 attttacgca ttttagctcg catctttgtt gaattttacc aaaatactcc cctcttggtg
    23461 cagtttgtta ttgtttttta tggcctacct cttatcagtg accatatcat catgattcca
    23521 atttattgga cagccgttct ctgcgtggga ctctatcacg gcgcttatat cgctgaggtt
    23581 attcgttcag ggattcagtc tattcctagt ggtcagatgg aggccgcctt gtcgcaaggt
    23641 tttacctata tcagtgccat gcgcttgatt atcttgcctc aggccttccg catcattctc
    23701 cctccattga ccaaccaaat tgttaacctc atcaagaaca cctctactgt agctatcatc
    23761 tctggagtag acttgatgtt tgtgactaag tcttggtcgg ctctcaacgg aaactatatc
    23821 ccagcctttt taggtgctgc tcttctctac tttgccctat gcttccctgt tgcccagttt
    23881 ggtcgcaaga tggagcaagc caacaaaaaa gcctattcac tttaggaggt tactatggaa
    23941 tctattttag aagttttaac cccagataac ctagtcttta tctttaaagg atttggcttg
    24001 accctctata tttctctgat tgccatcatc ctctctacta tcatcggtac ggtgctagct
    24061 gtcatgagaa atggcaaaaa tcctgtcttg cgaatcatct ccagtattta tatcgagttt
    24121 gtgcgcaacg ttcccaacct tctctggatt tttactatct ttttggtgtt caaaatgaaa
    24181 tccacaccag caggtattac agcctttact ctctttacat cagcagcctt ggttgagatt
    24241 attcgaggcg gtctcaatgc cgtagacaag ggacaatacg aagcaggaat gtcacaaggc
    24301 ttcacctcag cccaaatcct ctactacatc attctcccac aagccatccg caaaatgcta
    24361 ccagccatca tttctcagtt tgttaccgtg attaaggata ccagtctcct ctactctgtt
    24421 atcgccctac aagaactctt tggagccagc caaattctca tgggccgtta ttttgaacca
    24481 gagcaggtct tcagtcttta catcctgatt gccctcatct acttcagctt taacctagca
    24541 atttctagcc tgtctcatat gctagccaaa cgttggcaac aagctgcaga ataatactct
    24601 tcgaaaatct cttcaaacca cgtcagctct atctgcaacc tcaaaacagt gttttgagca
    24661 acttgcggct agcttcctag tttgctcttt gattttcatt gagtataaac agccactctc
    24721 cagttcaatt ggagagtttt ttgatgagag tagatattta tagacctcaa tttgacacca
    24781 tacattttct atgataaaat gtaacaaatt catttacaac aaatcgaaat ctaaatgaaa
    24841 tggaattttc tatgaaatca gtcaaaggac tactctttat catagctagt tttatcttga
    24901 ctcttttgac ttggatgaac acttctcccc aattcatgat tccaggacta gctttaacaa
    24961 gcctatctct gacttttatc ctagccactc gtctcccact actagaaagc tggtttcacg
    25021 gtttggagaa ggtctacacc gtccacaaat tcacagcctt tctctccatc atcctactaa
    25081 tctttcataa ctttagtatg ggcggtttgt ggggctctcg cttagctgct cagtttggca
    25141 atcttgccat ctatatcttt gccagcatca tccttgtcgc ctatttaggc aaatacatcc
    25201 aatacgaagc ttggcgatgg attcaccgcc tggtttacct agcctatatt ttaggactct
    25261 ttcacatcta catgataatg ggcaatcgtc tccttacatt taatcttcta agttttcttg
    25321 ttggtagcta tgccctttta ggcttactag ctggttttta tatcattttt ctatatcaaa
    25381 agatttcctt cccctatcta ggaaaaatta cccatctcaa acgcttaaat cacgatacta
    25441 gagaaattca aatccatctt agcagacctt tcaactatca atcaggacaa tttgcctttc
    25501 taaagatttt ccaagaaggc tttgaaagtg ctccgcatcc cttttctatc tcaggaggtc
    25561 atggtcaaac tctttacttt actattaaaa attcaggcga ccataccaag aatatctatg
    25621 ataatcttca agccggcagc aaagtaaccc tagacagagc ttacggacac atgatcatag
    25681 aagaaggacg agaaaatcag gtttggattg ctggaggtat tgggatcacc cccttcatct
    25741 cttacatccg tgaacatcct attttagata aacaggttca cttctactat agcttccgtg
    25801 gagatgaaaa tgcagtctac ctagatttac tccgtaacta tgctcagaaa aatcctaatt
    25861 ttgaactcca tctaatcgac agtacgaaag acggctatct taattttgaa caaaaagaag
    25921 tgcccgaaca tgcaaccgtc tatatgtgtg gtcctatttc tatgatgaag gcacttgcca
    25981 aacagattaa gaaacaaaat ccaaaaacag agcttattta cgaaggattc aagttcaaat
    26041 aagtaatcat actctcctgg gaaatcccag gagagttttt tatagccaaa tgaaataaga
    26101 caggaacgat ggaattttgg cattcaaatc aattgataag actattttat agtggagtga
    26161 aataggatac gaacaaattg attaggaaaa tcaaatgaat ttatagaaat cttttagcag
    26221 ttatgttatc ctattctagt ttcaaaacgc tatagaagca gcattgtgct agtctagatt
    26281 cagtttacta tactaaaacg agtagcttga aatcaaaaaa cccaccctca caggcaggtt
    26341 ttatctgtat tattcagcta gattatgctt taccttctga accgaatacg tcgatacgtt
    26401 cttcaaccga tgcttggata gcttttacac cgtcagccaa gaatttacgt gggtcgaaga
    26461 gttttttctt gtcgtattct gcttcgtttg cttcgtagtc acgagcaaat ttacgagttg
    26521 cgttagcgaa tgcgatttgg cattctgtgt taacgttaac tttggcaaca ccaagtttga
    26581 tagctgcttg gatttgctca tcaggaatac ctgatccacc gtgcaatacg attgggaatc
    26641 ctggaagagc ttctgtcaat ttttgcaagt ggtcaaggtc aagaccttcc cagtttactg
    26701 ggtaaggacc gtggatgtta ccgataccag ctgccaagaa gtcgatacca gtttcaacca
    26761 ttgctttagc gtcttcgatt ggagccaatt cacctttacc gatgattccg tcttcttcac
    26821 caccgatagt accaacttca gcttctactg agataccttt agcgtgtgct ttttcaacaa
    26881 cttctttagc caatttaagg ttttcttcaa ctggaaggtg tgaaccgtca aacatgattg
    26941 aagtataacc aacttcgata cactcaagtg catcttcgta gtgaccgtgg tcaaggtgga
    27001 tagctactgg tacagtgata cccattgatt caacaaggtt agcgatcaag ttgcgagcaa
    27061 ctttgtaacc acccatgtat ttagcagcac ccattgaagt ttggatcaaa actggagctt
    27121 ttttagcttc tgctgcgcgc aagatagctt gagtccactc aaggttgttt gtgttaaatc
    27181 caccaactgc ataaccgttg tcacgggctg cttggacaaa tttttctgct gaaacgattg
    27241 ccattttatc aggcctcctg tatattttta tgggtcatcc catttacatt gttcatttta
    27301 tcactttttg ccaaaaaaat ctagtttttc ccgcagtttc gattgatttt cttctaactc
    27361 catctatgta aaccctttct ctccctagtc ttgggcgact tttggaaaag ctataaagaa
    27421 ggttaaacga ttctcctcca tctcgaaacg ataagctaat ttttcatgtt ctaatagact
    27481 cttaaccaca aagagcccca taccagaccc cttgaccttg cgactggcat tgtcagaaaa
    27541 agactgggct agtttttctt gttcctctga gctacagcta ttttcgataa aaagttctcc
    27601 ttctctttct ccaattcgaa ctaagccacc tggaacagag tgcttaatgg cattgctgat
    27661 gagattagaa agaatcaact tcataactga tgggtttaga taagcctgct gatgggtcaa
    27721 actattgtct atctggagct ctctttcctt ggctagcaag gcataatctt tgaccagatt
    27781 ttgcgtcatc tggaggaggt caattgtttc cctatcatct cgcaattcct gcacagaaga
    27841 gagggaaagt atctgcagaa catggtgatt gagttcatcc acaatcccca aggcaactcc
    27901 cagatactgg tctctatcct tataacgacc gatattctct ctcatatttt cgattaggat
    27961 tttcaaacta gccagcggtg ttttcaattc atgagaagct cctcgtagga attcgacctt
    28021 catcttctcc agctggagaa tggcttcatt cttttcatgc aagtccgcaa taacagtcaa
    28081 gagatgctgg tagaggctat tgatttgttc cttgagatta cctatctcat ccttagaatc
    28141 cacgcgcaat cgcacttggg catccaggta catcatccga cgagtcaccc gcttgatttc
    28201 caaaatcggt gcaacaatag tccgagcgta gatgtaggcc accaagaggg aaatcagaaa
    28261 ggaggccagc aaggtatagg gaagaaactg gagactgatt tgctccgctt ccttttgtaa
    28321 atccatggaa gctagaaact ggagaatcat agtaccaccg tcttgcgttt tcacctcgcg
    28381 ctcctcaata aagagagagg ttgtctggcg gtctgtgtcc agaggaagac tgtccttgac
    28441 ttctaacttg tcctcggtca tctcaccttt gacggtcccc ttgatatcac tagtctggga
    28501 atacaagtct aacacttgct cgatactctg cctatctttc ccttctaggg actgggcaat
    28561 ggctgttgcc ttttgaccaa tggtttcctg acgatgactc agataagtcg aaggaaaaag
    28621 aaaataaata gctaaatgaa ggcagataac cagaacacta aatatcgaga aggtatagat
    28681 aaatatcttt gcaaataaac ctgttcgttt cattttcgct ccaatttata accaacattg
    28741 cgcacagtga ggatacaatc caagtctagc tttttccgca attccttgat ataaacatca
    28801 ataacacggt caaagggaac ctcatctgtc gctttccaga cggcatcgat aatctgagat
    28861 cgagtcaagg cccggccttc atttttcact agatagtcca gaatttccaa ctctttggca
    28921 ttgataggca cttcttgacc tgcgatgctt gcactgtagc tttcaaagtc caccttggta
    28981 tccttgtaag aaaagattcg tcctgtatcg tagtagcgct tgaaaatcgc gtccaccctc
    29041 acttttaaaa gggagaggga gaaaggtttt tccagatagc catctgccaa agaggcaaag
    29101 gcactcatct tgtattcctc atcctgaaaa gctgtcaaca tcaagacagg aacctgactg
    29161 gttttacgaa tctcagctag gacttctaag ccgttgagct tgggcatctg gatatccagt
    29221 aaaaccaggg ccacctcata gctagaaaat tgctccagag cttcctgacc gtccgctgcc
    29281 tcaatagttt catagccaca atccgtcaaa taatcactga ccccctcacg gatcatctct
    29341 tcatcttcta caattaaaat tttcatactt taactgctct ctatttttta tttttcttag
    29401 aataaatacc tactctattt tctattatag tctcttgctg gccttttgtc tgtaagtaac
    29461 tgaccactag ataaaacgtt gtgaaattcc tttctcataa attccataac tttagtatat
    29521 tatatttaag cactaaagta caaagaaagc aactgaaagc aatgattttc accactgctt
    29581 tcagatttat tttgaattgt taaatagcca ttcctatcca ctattcttga atagaaacac
    29641 aagatgcaat ctttattcca gactcatttt ttcaaattta ttcaccatcc agcaagagtt
    29701 cttttggttg ttttctaagg agattgcttg aagcaagcgc cataacgaga accactagaa
    29761 ccaaggcaag gacaaaaatg atgataaagt ctgatgtctg aatggaaatg tctaggctcg
    29821 acaaggtctt gctaaagcca tctacttctg caccaccacc aaggttagag gcttgagccg
    29881 ccttactagc ctgtttggca acacctgaag tcacattggc aaggacagtg tttccaattg
    29941 cacgggcagt gtaattagct aggaagtaag cagaaactag agcagggata gcaatcaaga
    30001 tagattcggt gatgaattga cccaagatac ttgcctgctt gaggccgata gagaggagaa
    30061 ttcccacttc cttgcgacgg gcgttgatcc aaaggctgag caagagggca aggaggagaa
    30121 ctgagaagct caagctaccc cagaagagga ggttggccat cttgtacata ccagagatag
    30181 attgctcaag agctgggtag ttagaggagc tcttgacgag tgtgtagctc ttccagttga
    30241 taccactgat gccattcaac tctttcataa catcatccaa gttcttgtct gctgttacaa
    30301 agaaggttgc gtccccataa atggctgtgt cttctgtgta tccataaagt tttgcagcag
    30361 tgtgaatgtc tgtaatagct gtgttttcgt aaagttcttg tgagtaggtt actgctgact
    30421 tattatgacc atcaaagagt cccttgattg tcacttcaac tgtttccttg gctccttttt
    30481 cattatctgc atcgtagata ttagagtcca gtttaacctt gtcccctact ttccagccgt
    30541 gtttggctgc caagtccttg tgcaagagga ttttatcctt gtcgtcgttg gttaagtgct
    30601 ctccttcgac tagtttataa gaaccagaga caaacttgtc ttctttagag gagtcattga
    30661 cacctgtaat catcaagcta cttccaaaac gtttggcacg atcagcagtg agattcttct
    30721 tggtttctgg cgtttcaatc aggtcatatc cagtcaaatc tccgatagcg ttgatacgtt
    30781 tgacataaga ctcgatggcc ttgttttcgg tgattttttt gatgtcttca cccttgatat
    30841 tcccagcacc acgaggcgtt ccttggttga cgcgacgatt gatttgcatg gagaagctat
    30901 tggtgatatt tttaaaggtc tcctgagaag ccttggcagt agctcccttg attgacaagc
    30961 cgaccaaact caagctcgcc atgaggagaa taatcaggaa gatgacaatc gatttgaaaa
    31021 acttccttgt aacataggca aatgcgttgt gtaacataga ttccctttct agattttgtt
    31081 ttaatcattc tatcaaaata agctcaaatt atttactagt attgcgcgtt tcagtcagtt
    31141 tcttatcctt taattcaagt gtaatatctg acgcttgtgc cacttcttta ctgtgagtta
    31201 cgacaatcac acatttacct gttttctggg caagtgattt gagtagttcg acaatatctc
    31261 cagcagtttt aggatccaga tttcctgttg gctcatcagc tagaataact ggagcttctg
    31321 agaccaaact gcgagcaatg gcaacacgtt gctgttgacc acctgataac tggagaacat
    31381 tccgcttgat ctggctttca tccaaaccaa gctcaagaag tgtatccttg cttgcctttt
    31441 tgttgaccaa gcggatattt tccagcggag aaagataatc tatcaagtta taattttgaa
    31501 agaccaggga aatatggtgc atgcgatggt aagaatagcc cttcttacga atatcctctc
    31561 cttgaaaaag gatagaacct tcaacaggac tatctagacc agcaagtagg gacaagagtg
    31621 tggattttcc tgctcctgac tccccaataa tactgtaaaa ttttccaggt tcaaaattat
    31681 aatcgatctg atataggact gcttcagcag tattcttata acggtaggta acatcttgta
    31741 attgtaataa agtcatgatt tctccttctt aactaataga tgataaaatt tctttcggtg
    31801 attttctaaa taagaatagg aaacaaaggg ctacagataa gcaactaagc agaactagaa
    31861 aaacatagga ttctgcaaaa gataagatgc tagttgataa actgcttgct ttggctagtg
    31921 tatcttgtaa gcttgcctga tctccacttg ctagtagagt ttggagtagg taagttgtga
    31981 ttgcgtttcc tgcaacaaat gctggaagca aagctccaag agataccaaa actacctcta
    32041 aacagaattg taggaagatc gagctcttgc cttttccaag tgcaagtaaa atccccactt
    32101 catagacccg ttctctcaac cagagagaca aaaccagaat taaggctcca gctcctgcta
    32161 tcaacatccc ataaaggaag atggtcagga aggtttggaa agttgcaact gagtctttga
    32221 tttgttcaaa agccttgttt tccttttcga cttggtagcc ttgattttcc aaggccaagt
    32281 tttctacctg cttcatgagt ccgtccattt tcttaggatt ttctacatag aagcgtgctg
    32341 cactgacttg agcttcacta ttgcccaaaa gggtttggct actttcatag tctgtaaaga
    32401 cttgattttc actgaagtca gaagacaagc ctgtgaattt ctcttgtttt ttaccagaaa
    32461 agatgccaat aatctcaaac tctactgttt gtccttttcc agattcagac tgaccagcat
    32521 ccaagccaat cttgtcatga agtgaaagac cgttcttctt agccaattct tcgtggataa
    32581 ggattttctt ggaatcccct ttttgaaggt gtcgcccttc ttttagattg aaagccgaac
    32641 tggtaaaggt tacatccttg gatgaatcct caagagccgt taagctaacc aagttattgt
    32701 ctgcagctga taaatcatca cgctccacgc tctgctcgcc agtcactgct tccttgtctt
    32761 ttagttttgc gaccgtctca agttcaggag agacattttc cagcccctta atcttgctta
    32821 cagatgctag gtctgacaac ttgaatgtct gaccattctc tatcttctta atagaaaaag
    32881 atgtattgag tgatttataa agattgcttt ctactgtttt gttggacttc atcagagtca
    32941 aacaggctga aattccggcc aataagacca ataaaatcag aaataaaata aaacttctca
    33001 gtcgctttct gctgacataa gcccaagatc tttggattgg attcatttgt cacctccata
    33061 tttgtaagac tattataaaa cccaaatatg aaatgtttat gaaatacgaa aaaaaaatat
    33121 cgagtagggg ataatctcta gcccctctca caccaccgta cgtgccgttc ggcatacggc
    33181 ggttcaacta acttttaacg catgtcgttc aaggtaataa tccaaacacg aaacctgttc
    33241 acgtttttca aggactggtt ttgatatagc acgtttaagt accgacttct gagctactat
    33301 agtagattga aactagaata gtacatctct tcttctaaaa cattgttaga aatcgatttg
    33361 gctgccctga tcaattcgtc ctactcttat ttcattttac tataattgat agtggtcgcc
    33421 ccagccagat accttatctg ctatccattt aggaacccct aacttaagca atccccataa
    33481 tcgtctcgat ttcttcttcc attgcttcca gataatcact cgtaggcgag tacgcaagcg
    33541 ctcatctatg ctagtgacta tacttttcat atttataatt cattcctttc gtttcactca
    33601 aggcacaaca cagaatgaaa aagtgttgtg atctttattt tgttttataa taatagtgag
    33661 aaagcctatc actactacaa atcacgggga ggtgaataag tgagtggtac agccactacc
    33721 tcgcatattt tgtcacatca tttaacggta cataataagt tgtaccatct gaataagttg
    33781 ctacaatatc atttgcatgc tctccttcac ctttagcaaa ggttggagct cctgctggat
    33841 gatttttatt tgcctctttc aatttttcaa taatggcatt tttttctgta tcttttatat
    33901 tatcaggatt tttcactaag attttgtctg gatatgtcgg tttagcagaa acaattttta
    33961 ctgttatttc ttttttattc gaagcacttg tccagtttcc agcattatct ttagtattta
    34021 attttacagt aattcctgaa ctaggaactt cagtagcagg ttgattatca acattattca
    34081 actttaattt caaaagagct gttgcatcag acgttttatc aatcgttata tataatgata
    34141 aattgttatt ataaccagtt tcttcatatt tagctgtttg tgagctactt gaaacagaac
    34201 tgaaattatg cccactacct ccctgattat cttcaatgct tacgtctaaa tgaacttccc
    34261 cactattatt tggcttagca acaactgtta tagtaaaata acataaaatt tgcataaata
    34321 gattagggaa atcaaagcaa cttctaggaa tgttttagca gtcacagtgt actttcccag
    34381 catcaatcca ctataactct gcacataaaa atggagaaga tggccatcct cttctccaaa
    34441 tattaacttc tttacaaacc aactatagtt gacaaagaac ctaaaatcaa ttgataacac
    34501 aaggtcaggt cggtcaactc tttcaactga agccctgtca actcttccca tttatcaatc
    34561 ttgtattgga gagaattgcg gtgcagatag agttgctggg ctgttttagt gagaacagca
    34621 ctattttccc aaagagagag aatgatttcc tgaatctgat cttgatccaa aatcatctgg
    34681 tgtagacatt ctttaattgg cttcaagtcc acgagtcttt ctcccatact ccaaagatag
    34741 agctgagaaa aagtatgaac accttggtga ccctgacgcc accatgtctt gaacaaatcc
    34801 cgctcagctt tgattaagtc tgatagggct tgatgtcctg tctgagacca aacctgaccc
    34861 aacatgatag aaagacgaag tccaaagtca tactcaaccg cttcaatcgt atcacttaaa
    34921 atatctctta cagaagtgta tttgtcttgt tgaagcacga aaacataatc ctgagatccg
    34981 acctgtagca ctgtctgaca attcggaaaa agagtccgca tcatatctag ccaagaagcc
    35041 agattttcct gctgaaaata agaaagatgg caataaacca actgaatctt tttaaaaact
    35101 tgcggtgcct gtcccttgcc ttcaaccaga taggaatacc aagggtttag cgaacgagcc
    35161 tgctcctgct gggtcaaaag ggcaaccaac tgcttttcac gctcgctgag cccagcttcc
    35221 tccagcaaaa tccactgctg agaagctaaa gggagcgtga gatagccctc tttctctact
    35281 ggttggtctg aaatccgagc ctcaggaaac cagtcttgta gttctttttc cctcatgttc
    35341 tagccctcca ctttttggat gcaccatgaa accaaactct caagacgttc cagattctca
    35401 gtcatatgga gatagcccat aaccgcttca aatcccgtgg acatacgata agtcacgaca
    35461 tctgcatttt tagcctttgt gtggctattg gtattgcggc cacgtttgta gatttcttct
    35521 tctttttccg ttaggacctg ctcctccaac atgagagcaa tcaggcgagc ctgagccttg
    35581 gctgacacat acttggttgc ttcttgatgg agtttattgg gtttggtcat acctttgagg
    35641 atgaggtgac ggcgaatata catagaatac accgcatccc cctcaaaggc tagcgcaatc
    35701 ccgttaatga gattgacatc aatcacgtgt ccacctcact ccatccttgg tatcaaggag
    35761 cttaattcct tgagtaacca attggtcacg gatttggtct gctgtctcaa agtctcgatt
    35821 ggcacgcgcc tcttggcgtt tttgaatcaa gtcttcaatc tctgcatcca aaacttcctc
    35881 aacaaagaca attccaaaaa tttctaacat atctgcaaga gcttgcttga cacttgcatc
    35941 atagttccct gagttgatcc atttggccat ttcaaagaca actgtgatac cgttggcagc
    36001 attaaaatct tcatccatag ctgctacaaa cttatcttta aagttttgta actcttgggc
    36061 atccacgttt cctgtaaatg gttgttcgta agtattcttc agatacttga gattggtctc
    36121 ggcatcgcga actgcctttt ccgtgaagtt gataggctta cggtagtgct gggtcgcaaa
    36181 gaagaaacga agtacttgcc catcaagagt tttaagggca tcgtgtaccg taatgaagtt
    36241 acccaaggac ttagacattt tgacattgtc gatattgaca aagccattgt gcatccagta
    36301 gttagcaaaa gccttgcctg ttttagcttc agattgggca atttcattgg tgtggtgtgg
    36361 aaactctagg tcagctccac caccgtggat atcaatggta tcacctaaaa tctctgtcga
    36421 catgactgaa cactcaatat gccaacccgg acgtccaggt ccccaaggac tatcccaaga
    36481 aatctcacct ggtttggaag atttccatag agcaaaatct acaggatttt ccttacgagc
    36541 cgtttcttca tcggtacgac ctgaagcacc tagctccaaa tcttccaagg ttttattagc
    36601 caatttagca tagttgtggg atttttctac acggaaatag acatcccctt gactctcata
    36661 ggcaaagcct ttctcgatca agtcttccac aaaacggatg atgtctgcca taaactccac
    36721 tacacgcgga tggcgagtcg caggtttcac gcctaaggcc gtcacatcct cacgaaaggc
    36781 agcgatgtac ttatccgcaa cctcctgagg tgtgatgcct tcttccctgg cacggttgat
    36841 aatcttatca tccacatctg taaaattgga aatataggca accttatacc cacggtactc
    36901 aaaatagcga cgaatcgtat caaaagctac cgtcgaacgg gcgtttccca cgtgaatata
    36961 gttgtacacg gttggcccac aaacatacat cttgatcttg ccgtcctcaa tcgggacaaa
    37021 ttctcgcaaa tcacgagaca tggtgtcata gattttaatc ataaatcata atcaagaaag
    37081 ctaaaatcca agaactgtta gtttcatcac taaactaaga gctcaagtaa atttcagtcc
    37141 gaatgtctct acacttcgga atcccttgct cctttctcat tcagataaac cacctgtgtc
    37201 tgtttgacaa agccaatttt ttcatacaaa cgtttggcac ctacattgct atcttccact
    37261 gcaatctgaa attccttatc attttgctca attagttggt tgacaaggga ttttgctaag
    37321 tagcttccat agccttttcc acgttcaggt tctgatattg ctaaaccgta gaagtaattc
    37381 gtatcgctcg ataaatcaac cgtgcaagtc ccaataacct gaccgtcttt taacaaaata
    37441 tataagcgac tttctggatc cttcagagct tcagcgacat atctatccac aacttctctc
    37501 gattcatgtt cccctgaaaa tgcctgaaat tttaactggc taatttgctc ctgatacgaa
    37561 ctatctgcta acaaaacttc aagattagaa agttttgcta actgatatgg tcttctatcc
    37621 ttacctaacc aggtttctgt ctcttcatcc tcgattagtc cccagttact ggcaaagtca
    37681 ggatgattct ctaaaaaaat acgttctgtc tgaaaagtga ctgaccgaat ggggaaagaa
    37741 gctgtttctc tctcaaaact agtaaacaat gcacgcgcaa tcccctgacg gcgatgacct
    37801 ggatgaacca gtatcgtcac ttctacatct tggtcatctg catagacagt taataaacca
    37861 acaagtttgc ctttttcata ataaaggaaa aaggcgggca tgtttgggtc aaaattaagc
    37921 atgttagaga gatagggatc gcgataggta ccgtcatagt tttggcaaca gttaattact
    37981 tttttcgcct cagatagctc ctcttggctt aacttgtttc ttgcttgaat catataggta
    38041 tcctctacaa accagacgat ctgtgactgg catctttagc ctgctcgagt ttattgacat
    38101 aatactcccg tttttcttcg acttcgtgaa taacaggctc atctttctta ccatgaagac
    38161 ggacaatctt ggccggaata ccgacaaccg tcacatcact aggtacatct gctacgacaa
    38221 ctgctgcagc accgaccttg gcattttcac caatttccac aggcccgata acttgggcat
    38281 gggctgatat gagggctccc tttcgtacag tcggatggcg tttgccacag tctttccctg
    38341 ttcccccgag agtcactccg tgatagagaa gaacgccttt ttcaacaatc gctgtctctc
    38401 caatcaccag accagaacca tggtcaataa agacacctga atcaatctgg gctcctggat
    38461 gaatctcaat ctgagtccaa aagcgccaaa actgactgtg catacgagct aagagtttga
    38521 agtcgtactt ccagagaaaa tgcgagagac ggtgggccgc caaggccttg acacctggat
    38581 aagtcagcaa aacctccaaa gtggtgcggg ccgctggatc attttctttt acgatatcaa
    38641 tggtttcgtg ccaccacccc atacatttct ccttttctta ctctgaatct tttggtgttt
    38701 ctgtaaattc tttcttaggt ttgtgatcct tgtgatgacg tgggcggtga gggcgctcag
    38761 acttttcacc tttttcatca tgctcaggtt ttggcggacg aggtagaaga gccttcatag
    38821 aggcatcgat acggcctttt tcatcaatct tgataacctt aacatcaact tcatccccga
    38881 tttctaccaa atcctctaca cgattggtac gagtccaagc catctcagag atatgaacaa
    38941 gggcatctgt cttatcaaag aggttaacaa aggcaccaaa tttctcgata cgaacgactt
    39001 tagcacggta aacttcatcc actttggctt cacgaaccaa accagcaata atttctttgg
    39061 cacggttaat agcatcttgg tcactagagt agatagacac atttccttct tcgtctatat
    39121 caatcttaac acctgtttca gcgataatct tgtcgatggt ttctccaccc ttaccgatga
    39181 caatcttaat cttgtccaca tcaatcttga tcgtatcaat tttcggagca gttggagcca
    39241 attctggacg aacttctgga atggttgctt caatgacatc aaggatttca aaacgcgctt
    39301 tcttggcttg agcaagagcc tccgtcaaga tttctgcagt aatcccttga atcttgatat
    39361 ccatttgaag ggctgtaatc ccatcacgag tacctgcaac cttgaagtcc atatctccaa
    39421 agtgatcttc caaaccttgg atatctgtca atactgtgta gttatttcca tctgagataa
    39481 gtcccatagc aataccagct actggcgcct tgattggcac accaccagtc ataagggcaa
    39541 gagttcccgc acagatagaa gcttgagatg aagaaccgtt tgattccaaa acttctgcta
    39601 ctagacggat agcgtatggg aattcttcca agcttggcaa gacttgagca agagcacgct
    39661 caccaagggc accgtgaccg atttcacgac gacctggcgc accgtaacga cctgtttccc
    39721 ctacagaata ttgagggaag ttatagtggt gcataaagcg tttcttgtac tctggatcca
    39781 aaccatcaat gatttgagtt tctcccatcg gagccaaggt caagactgaa agagcttgag
    39841 tttgcccacg agtaaagaga cctgaaccat gtacacgagg aaggaagtca acaaccgcat
    39901 ccaaaggacg gatttcatcg accttacgac catcaggacg caccttgtct tctgtaatta
    39961 aacgtcgcac ttctgcgtgt tccatttgtt ccaagatttc agccacatca cgcataatac
    40021 ggtcaaattc ttcgtggttc gcatattttt cttcgtaaac ggcagtcact tggtctttca
    40081 ctgcttgagt tgcagcttca cgggccaatt tctcttctac ttgaactgcc ttttggaggt
    40141 cactgttgta ggctgcaatg atttcagctt gcaattcagc atccacgtga agcaattcca
    40201 cttctgcttt ttctttaccg acagcagcaa cgatttcttc ttggaaggca atcaattctt
    40261 tgacagcttc gtgcccttta agaagcgctt ccaacatgat ttcttctgac aattctttgg
    40321 caccagactc taccatgttg atagcgtgct tggttccagc tactgtcaat tcaagaagag
    40381 attgctctgc ttgttcttga cttgggttga tgatgatttg gccatctaca tatcccactt
    40441 gtaccccagc aattggtccg tcaaatggaa tatctgaaat agacagtgcc aaagatgaac
    40501 caaacatagc agccattggt gcagatgcat tttcatcata agaaagcact gtattgatga
    40561 cttggacttc attacggaaa ccttccgcaa acataggacg aatcggacgg tcaatcaaac
    40621 gcgctgtcaa ggtcgcatct gttgaaggac gtccttcacg tttcataaag ccaccaggaa
    40681 acttcccagc cgcatacatt ttttcttcgt agttgacttg gagtgggaag aaatccccag
    40741 ttgccatttt cttagacata acggcagcag tcaagacagt tgactcaccg taacgtacga
    40801 caacagagcc atttgcttgc ttagcaacct gaccagtttc tacaattaac tcacgacccg
    40861 caaaagtcgt ttgaaacact tgttttgcca ttttaatccc ctttggattg atgaaattat
    40921 acgccttgcc tacaaagatc aagataccaa ggacgtcaaa agcaaagtaa aaataggaaa
    40981 ctgacgaagt cttcgatgaa gacaagacag tttatctttt ttacacagct tttcggccgt
    41041 gttcaattac acaagatatt ttggacggtt cggcttgccg aacatttctg tagaaaaata
    41101 ggaaggtgac gtcgcactcg acgagtgcta ggaagcttat cttttttcct aagaaatgag
    41161 accaaaattc aattactcaa gatactaagc cgtcaagcaa ctcaaaggaa aataggaaat
    41221 cgaacgacgg agcgactgct cctagggaga tttatctttt tccacagagt tgtaggcgag
    41281 ttcagttttc aagatataaa tcattagaaa ggtttaatac taaagtatct aaagctttca
    41341 cgctaatcgc tatcgggcga ttagttaaat gctttactaa ctctctcgtc aaataacatc
    41401 gatttgactc actcgtgtcg ttaaatctta cagtttaaat gcattgtatt atttaatacc
    41461 ttcatctttg tatcaagtac gtacagaatt tattttatca tatttttctt aaaaagtgag
    41521 gtctttacca ttaaaaagga accattcccc tcacctgaga agaatggttt gcttttatta
    41581 tcctagagac tggtgattaa acaaggcatg ggttgcttga tggatgtatt ttgctgtatc
    41641 agcattattc atcgtataga gatgcacacc ggcaacatcc tgagttacca agtccacgat
    41701 ttggtccact gcataggcaa gtcctgctgc tctgagcgac tcagggtcat gctcatactt
    41761 gtctaagatg gctttaaatt tgcgtggaag atggatattc tcacaagtct tcaagagtcg
    41821 gagagcctga tttcgattca gaattggcat aattcctgca tgaatgggaa catcaatccc
    41881 agccaagatg cacttgtcct gaaaatcata gaagcgctca ttgtcaaaga agagctgagt
    41941 tacgaggctc gaacagcctg catccacttt cttcttaaga ttttgaatat ctgaaatctg
    42001 atttggcgaa tctggatgcc cttctggata gcaagctcca ataatatcaa agtgaggggt
    42061 ttgttccttg ataaactcaa tcaagtctgt tgcatagcgg aaatcctttt gtggttccac
    42121 gtctggaata atatccccac gaagagccaa gattttctgc accccaactt tgtccaagtc
    42181 agcaatagtt tcagcaacct tgtccttagt tagataaata gctggcaagt gggcaatggt
    42241 cggaatcgcc aaatcatttt ggataaagtc agccaaacga accgtcgttt ccttgatatt
    42301 aaatttatta ttgctggcag ttacactgat aaaatgggga gccaactcct gcatatcctg
    42361 caaggctgaa ataatgttat cattacccac ggctgggttt ggagggaaca cttcaaatga
    42421 gagtgacggt gtttggcgtg acatatgtaa taaccttttc tagttgattt ctttttgaac
    42481 aaccactgta tggagagaaa tccaatctta caatttctca cgcgcagctt tagctgcttc
    42541 aacaaggcgg atcaagcttt cttttgtttc tgggatacca cgtgttttca aaccacagtc
    42601 agggttgatc caaactttct tgcttggcac tttagcaagg atgacttcga ttgtgttgtc
    42661 gatttcgcct tcatttggta cacgaggtga gtggatatcg taaaccccag gtcccacttc
    42721 tgtttggaag tttttcgctt tgagttcgtc caagatttca aggtttgaac ggctagcttc
    42781 aaaggaaata acgtctgcat ccatgttatc gatagctggg atgatatctg taaattctga
    42841 gtaacacatg tgagtgtgga tttgtgtgtc tggcgctact gttgagtgta ccaagcggaa
    42901 ggcaggaata gcccagtcaa ggtagtcttc gtaccagtcg ctacggcgga gtggcaattt
    42961 ttcacgaaga gcagcctcgt cgatttggat gattttcaca ccagcagctt caaggtcaag
    43021 tacttcatcc ttgatagcaa gggcgatttg gagagttgaa tccttgatag agatgtcttc
    43081 acgtgggaat gaccagttaa ggatggtaac aggtccagtc aacatacctt taacaggttt
    43141 gtttgtacga ctttgtgcat agctagacca tttaacagtg atagggttaa gacgagtgac
    43201 atcaccccag atgattggtg gttttacccc acgcataccg tatgattgta cccatccatt
    43261 tttagagaag aggtatcctg acaagttttg accgaagtac tcaaccatgt cattacgctc
    43321 aaattcaccg tgaacaagga catcaaagtc aatatcttct tgccacttga tccattcgtc
    43381 aatcgtttca gcaaggaaag cgtcgtactc tttttgagac aattcacctt tacggtaagc
    43441 caaacgtttg gcacgaactt cttttgtttg agggaatgaa ccaatcgttg ttgttggaag
    43501 agctggaagt ttgaaagctt cttcttggat agcttcacgt tctgcaaagg ctggcaaacg
    43561 agtgtagtct gcgtctgtca agccagcgat acgcgcacga agttcagcat tttcaccaac
    43621 acgctcagtc gcaaagagtt ctttgttggc tgcaagagct tctgaacctt gaccatttcg
    43681 gatagcatcc aagtcacgga tttcatccaa tttttcaact gcaaaggcaa agtggttcaa
    43741 gagtgctggt tcaaattctt cattagcagt tgtaaatggc acatgaagaa gtgagcaaga
    43801 gcttgtcaaa acgatgtttt cagctgggat ttgctcaaga acagtcaagc tcttttcgta
    43861 gttgttgcgc cagatgtttt taccattgac aatacctaca tagagagtct tgtcagctgg
    43921 gaagccacct ttaacgagtt caagagtttt cttaccttca acaaagtcaa gaccgatagc
    43981 atctactggt aagtttacaa ggtcagcgta tacgtcacga acatcaccga aataagtttg
    44041 aagcaagact tcaagacctt ttttgtcagc caagagtttg ttgtaaaggt tcaagaaaag
    44101 agctttttct tcagctgtca agtcttttac aagagccgct tcatccaatt ggatgcgagt
    44161 cgcaccaagt tcagccaatt tagcaaaaac ttcttggtaa gcagacacta agctatctac
    44221 gaagtcgtct gctttcacgc cttcttcaaa gtctgacaat tgaaggaaag tgaagggacc
    44281 tacaagaaca ggacgagtgt tcaatccaag ttctttggct tcttggaact catcgaaaat
    44341 cttgtgacca gccaatttta cttgagtgtc tttttcaaat ttaggaacga tgtagtggta
    44401 gttagtgttg aaccatttct tcattggaag ggcgcgaacg tccccttttt ctccctggta
    44461 accacgtccc aaagcgaagt agcgctcaag gtcagacaag tccaagtttt gaacggatgc
    44521 aggcaccacg ttgaaaagga aagccgcatc taggaagtta tcatagtgag aaaagtcatt
    44581 tgatggaatt tcagtgatgc ctttttcttt gacaatgttc cagtgtttag cacgcaagtc
    44641 ttttgctgct gctaaaagtt cttcttctga gatttctttt ctaaagtatt tttcagttgt
    44701 aaattttaat tcacggaatt cgcccaaacg agggaaaccg atgattgtag ttgacatgat
    44761 gtgtcctcca aaatttgttg ttgaaactat cttaacagaa aagaaagcgt ctgtataatt
    44821 gtaaaaaatt agggtttgat atagtttgaa actatatatc tgtttcggac aaaagaaaaa
    44881 gacttgaagc aaacgtctca aatcctttgt aattcttact ttacagctat attccaatta
    44941 gaatactaaa acatgttatt agtaattctt ataagtgact atgacctgtt attagaaaag
    45001 actataactg attctagtca actttttccc tgttcaagtg ggacgactgc tagtgtcttt
    45061 cctaaactgg ctaggacttt taagactgta tccaactgag gactagtctt tcctgtctcc
    45121 atcctagcta tgacaggctg gcttattcca ctgacttctt ccagcttttt ctgactgatt
    45181 ccttgttcat acctagcctc aatcaactcg ctcatgatag ccactcgcat atcactttca
    45241 aggatttcct ccttgctaaa gagctcagat ggacatcctt ccaattactc ccaatagcac
    45301 tattcttcat cacttaaccc tctttttttt acgtctatgt atttttaaaa aaatgagcga
    45361 attatgattc gatagattga ccagtgggtt taaagttggt gctagcctat ttcttaagcg
    45421 attttccttt tctaggataa agcagatcct gcttgcttaa ccccaatttt ccacgatgaa
    45481 tccaatagta aatggttgaa attcccacgt taaccccttt aaccataacc atcatttcag
    45541 gcgaaaattt ttggttatgt atagtggaga atcttttcct ttagtttctt aagactgttg
    45601 agcgtagtcg gcagaataaa cctctttgaa gcgccctttt ccaagacatt gtcggactgt
    45661 cccacgcttg atttcagtgt ggatagtttg aggaactttt ccaagcagag aggcaatttc
    45721 tctatttgat ttcccttctt ttttccatct ttcgattaag caacggctat cgattgtcaa
    45781 atgtttgcct tttgtagtat aattgtcttg catttctgtg ccttttaatc atttcaatct
    45841 taaattggac tttttttact tgggttgtac ttaatctatg aggaagacaa gaaaaagaat
    45901 atcaatcaag taaagtcaca aagtcacatt agctccgagc aaccattgca aattgaggta
    45961 ctcacacaat gattaaaaca tttctctctg ccctttcggt cattctcttt tctatcccta
    46021 ttataactta ttcttttttc ccatcttcta atcttaacat ttggctatct acccaaccta
    46081 tcttggcaca gatttatgcc ttccccttag ctactgcaac tatggctgct attttaagtt
    46141 tcgtattttt ttccctatct ttttacaaga aaaataaaca aatacggttt tactctggca
    46201 ttttgctctt actatcgctc atattactat tattcggaac agataaaacc ctttcttctg
    46261 catcaaataa gactaaaacc ttaaaattag taacttggaa cgtcgctaat caaatagaag
    46321 cacaacatat tgagcgaatt tttagccatt ttgacgccga tatggctata ttccctgaac
    46381 tagctaccaa tatcagaggt gagcaagaaa accagagaat caaactattg tttcatcaag
    46441 ttggactttc tatggccaac tatgatattt tcacttctcc acctaccaat agtggaatag
    46501 ctcctgtgac tgtgattgtc aagaaaagtt atggtttcta tacagaagct aaaacttttc
    46561 atacaacacg gttcgggaca attgtattac attcgagaaa acaaaatata ccagatatca
    46621 ttgccttgca tactgctcct cctctgccag gtttaatgga aatctggaag caagacttaa
    46681 acatcattca taatcaattg gcttcaaaat atccaaaggc tattattgca ggtgatttta
    46741 atgcaactat gcgtcatgga gcacttgcaa aaataagctc tcatagggac gcattaaatg
    46801 tactaccacc ttttgaaaga ggaacttgga atagccaaag tccaaaactt tttaatgcaa
    46861 caatagatca tattttattg cctaaaaacc actactatgt taaagattta gacattgtaa
    46921 gttttcaaaa ctctgatcat agatgtattt ttacagaaat cacattttaa ttattttata
    46981 ctcttcgaca atctcttcaa accacgtcag cctcgcctta cagtactcaa gtacagctta
    47041 cggctagctt cctagtttgc tttttgattt tcattgagta ttatataaaa tcacccctct
    47101 agtgttcata aactagaggg ggaatttgta tcctactatc gtttaacgca cttctgcgtt
    47161 cacttttttt tcaagcgatg cttggatttt ttccatgtag cgtgcgactt cttcgtccgt
    47221 taagctgtct tctggatttt ggaaggtcaa gctataagcc attgacttca taccaagtcc
    47281 caatttctca cctgagaaaa cgtcaaagag tttgatatct gtcaaacgtt tcacgccggc
    47341 agcttggata gcatctataa cttcttggtg agttactgct gccttgagga gaagggaaac
    47401 gtcacggctg actgctggga atttcgtgat ttccacaaat ggagcagcag gttgaagggc
    47461 agcttcgatg actgaaaggt tgagctcagc cacatacgtt tctggaatat cgtaagcctt
    47521 agcagtgact ggatgcactt ggccaagaaa accaagaact tggtcaccga gtgaaatgac
    47581 tgctgtacgt cctgggtgaa ggctggcaat ctcagctgtt gctgtatagg tcacttctag
    47641 tcccaagcga gtaaagagcg cttctaggat tcctttagca tagaagaaat caactggaac
    47701 tgctgctgtt tggaaatctt tttcagcaac caagcctgtc aaggcaaagg caaaactgtt
    47761 gatttcattt ggaagttctt cttttggatt acctgtttgt tcaaagactt ttccaatctc
    47821 gtaaagggcc aagtttttat tcttacgagc cacgttgtag gcaacggtat caaggatacc
    47881 tgaaatcata ttttgacgga ggactgaacg atccacagtc attggccaca tgagttccgt
    47941 aaggttactt ggttgagccg taaactcaac tgctttttca ggagttgtta gagcataggt
    48001 gatgatttct gtcaaacctg ctccttcagc aatggtacga acttgacggc ggagtttttg
    48061 tgtcacagtc aattcaccag ctgtaccatc gtcttttgga aggctggttg gcaagcggtc
    48121 atatccatag atacgagcga tttcttcaaa gagatcagct tcgattgtga tatcccaacg
    48181 acgacgtggt acgctgactg taaagctgtc tgcatttcca gaaagaccaa agccaagacg
    48241 acggaagacg tcttcgacat cagcataaga cagctcagtt ccgaggacac ggttaacatc
    48301 agcaagagtt gaagaaactt ctacatctga agtatcaagc tcacccgctg aaacgatacc
    48361 cttacgcacc gtcgcacctg caagttccgc aatcaggcta gctgccgcat caagggcttc
    48421 attaactgtt gccacattaa ttcctttttc aaagcgagaa gatgactcag aacgaaggtt
    48481 caggcgacca cttgtcttac ggatagattt gccattgaaa acagcagctt caaggacaac
    48541 atgactagat ttttcagaga tttctgttgc ttgaccaccc atgacacctg caagggctac
    48601 tggcttgtct gcaacagtga tgactaggtc attcacgtcc aagtcacgtt cttcaccgtc
    48661 caaggtcacc aatttttcac cagcacgcgc ttcacgcaca cggatgtcag tcccttcaaa
    48721 tgtgtccaag tcaaaagcat gcataggttg accaaagtag agcaggatgt agtttgtcac
    48781 gtctacaacg ttattgatgg gacggatgcc ttcgttcatg agaaggtttt gcaaccattg
    48841 tggacttggt gcgatagtca cattgtccaa gatacgagct gcatagtaag gcgccttgtc
    48901 tgtctcaatg cccacagaaa gggcatctgt cgcagcttca tttgtttctg tcaaagtaaa
    48961 ttctttaaag ttgactgcct tgtcatatat ggctgccact tcgtgagcca ctccacgcat
    49021 agaaagggca tctgcacggt ttggtgtgat agaaaattcg atgatttcat catccaagtc
    49081 tagatatgaa aagacttcct cacctggaac ggcattttct ggcaaaattt gaataccatc
    49141 tgcgaatttc ttaggtacaa ctgagtcaga aatacccaat tcaccaagtg aacagatcat
    49201 tccaagtgac tctaagccac ggatttttcc ttttttgatt ttgtaattgt cagcgatacg
    49261 agctcccgga agagccacca taaccttgat gcctgcacgc acatttgggg caccacaaac
    49321 gatctgacgc tcttcttctt cgccaacgtt aacctgacaa acatgaaggt gagtttctgg
    49381 cacatcttcg caggacaaga tctcaccgac gacaattttt gaaagaccgg cagctggtga
    49441 ttcgacacct tcgacctcga tccctgtggt tgacattttt tcagccaact cctgtgatgg
    49501 cacatcaatg cccaccaatt cttttaacca tttataagat acaagcataa tttagttctc
    49561 cagaatgacc attgccacac tggttctttt cctttcctat catttcaata gaagaattct
    49621 cttcttacct taatttcttt ctcagtaacc aatccgtatc tactttttga ccaaccataa
    49681 aatgatgttg gctaaatttt tcaaaaccat atcggttata aaacgcttga gcttttgtat
    49741 tatgctccca aacacctagc caagcccaag aaaaactatt ttttgtagca agttcaagtg
    49801 cgaattcaaa cagttgctta cctagtccaa atccttggaa tttttgtagc acatagaggc
    49861 gttgaatttc aaaagcgtcc tctaattctc tctcagtttg agcacttccc cagttgactt
    49921 tgagaaaacc agctatctcc tcctcatgca taatgaaata ggtttcagag tcaggatttc
    49981 ccaactcagt tgacaaagtt ttcagactat aagcctcttc aaagtattcc tgtaactgct
    50041 cttccgtatt atcatacgca aaggtttcac gaaaggcttg tttggcaatt ttagccaaca
    50101 cctcaacatc tgccatttct acttttctaa tcattattta aactgttctg agaagcggac
    50161 atctccttgg tagaatccac ggatatcgtt gattccataa cggagcatag ctacacgctc
    50221 ttgtccaaga ccaaaggcaa agccagagta tacagtcgca tcgataccac tcatttcaag
    50281 gacacgtggg tgaaccatac cggcccccat aatttcgatc caacctgttt tcttacatac
    50341 gttacagcct tctccaccac atttgaagca agaaacatcc acctcaacag atggctctgt
    50401 gaatggaaag taagatggac gcaaacgaat ttgacgctct tcaccaaaca ttttttggac
    50461 aatcaactga agcgttcctt gaagatcagc catagagata tttttcccaa ctaccaagcc
    50521 ttcgatttgg tggaattggt gactgtgggt cgcatcgtcc gtatcgcgac ggaagacacg
    50581 ccctggcgag atcatcttca aaggaccttt agaaaaatca tgggcatcca tagcacgcgc
    50641 ctgaactgga gacgtgtggg tacggagcaa gatttcttca gtgatataga aagtatcctg
    50701 catatcacga gctgggtggt cttttggaag gttcatacgt tcaaagttat agtagtcttg
    50761 ctccacttca aaaccatcca cgacttgata acccataccg atgaagatat cttcgatttc
    50821 ttcactggtt tgtgtcaaaa cgtgatggtg accagtcgca actggacgac ctggaagcgt
    50881 cacatcgata ctctcgctag ccagttgagc cgcgactttc ttttcttcca agagcttagc
    50941 tgtttcttca aaagcagcag tcaagacatc acgagcttca ttgacgtgtt tcccgatgat
    51001 tggacgcatc tcagcagaaa catctttcat ccctttgagg atttcagtga gcgaaccctt
    51061 tttaccaagg acagagacac gcaaatcttg catctctttt tcatttccag cagtaatctg
    51121 cttcaagcta gccagcgttt cttcgcgaag cgcttttaat tgttcttcaa tagttgacat
    51181 atttcctcca tcagtctctc gtagataaaa agaaaaccac atgccaaaaa ctccactcgg
    51241 agcgttgaca cgcggtacca tccgttttca tctgacaagt cagaccttca tttctaaatc
    51301 catgcgcaag tgaattcacc cagctttcat atagagagct tgcagtcacg gctctcctcc
    51361 ctgatatact tcccttgggc tactagtctt tcagattcct attcaattac tacttagttt
    51421 atcagatttt taccattctt gcaagaccta tcttacttct gcttgttagc ttattcttat
    51481 ctaactttat agcggattga aataagatga aaacaaatcg attgggaaag taaaattaat
    51541 ttctataaat gttttagcaa ttgtttcgta ctattttaga ttcagtctac tatatataac
    51601 ccatctatcc taagttaact atttataatc ggctctctgt aacaaaatta aattaattaa
    51661 tccccctata aaataaagag gtttagaatt tgatgtcttc caaacctctt tatttcatat
    51721 ttaatgagat gttgccttaa ccgtgataat atctaatcat caataaacaa actatttgaa
    51781 taaggattct ccatttgatt caatcactcc tttataccaa gtaaaggaca ttttcttata
    51841 tcgattgaat gtgccatttc catcatcatt tcgatcaaca taaatgagac cgtacctttt
    51901 agaaagttgt gcagtggaca tagaaacgca gtcaatacat ccccaagatg tatagcccat
    51961 aatttcaaca ccatcctgta gagcttcagc aacttgcaat aaatgttctt tcatatactg
    52021 aattctataa tcatcttgga cggttaagtt attaagttca tcttttatta gttgatcttt
    52081 agcacctaat ccattttcta ctataaataa tgggatttga taacggtcat aatatctatt
    52141 taaaattata cgtagtccaa ttggatcaat ttgccatccc cactctgaag actctaaata
    52201 aggatttact aaaccaccaa taatattccc ttctcctgaa ttatactgtg ttggaagagc
    52261 agattgagtc acactcatgt aatagctaaa ggataaaaaa tctacggtat aattttttaa
    52321 taactctgca tcttcagctg caaactctat gttaatgtca tgttccttaa aatatctttt
    52381 tgcataattc ggataataac ctctaacatg cacatctgaa aatagataat ttagattctc
    52441 atactcatga gtcgcccata catcttttgg atttggagtc attggataag ctggcatagc
    52501 taataccata caccccacct taaactctga attaatctca cgagcaattt ttgtaaccaa
    52561 acttgaggcg actaattcat gatgtatagc ttgatataat tcttgtttcg aaagattctc
    52621 cttaggtata tctattcctc cactagtaaa tggtaattcc aaaacagagt ttacttcgtt
    52681 aaatgtaagc caatatttaa ctttatcttt atacctttct aaaactgttc gagcaaattt
    52741 ttcataaaaa tgaatcattc tcctatcaac ccatccatga tattttcttg ctaaatataa
    52801 tggagtctca tagtgtgaaa gagttacaag tggctctatc ccgtgagcat gtagttcatc
    52861 aaacaattca tcataatatt tcaaaccagc ttcgttaggt tcttcttcat ctccttttgg
    52921 aaaaattcta ctccatgcaa tagaagtacg aaaaacatta aagcccattt cagaaaacaa
    52981 ggatatatct tccttatatt tatgataaaa atcaatacct atcaatttta agttatcttc
    53041 tgtaggattt tctgttgctt ctcctaatcc acctttgggt aacacatcct gaactgataa
    53101 gcccttacca tcttcattat atgctccctc tacttgatta gctgcaacag ctccacccca
    53161 aagaaaatca tctggaaaaa tggtcataac tttcctccat tataatatta ccagtaattc
    53221 cttagaatgc tcgattgtct gattattagg taatactaat acatctagaa aatcattggt
    53281 attcgttaca attactggtg taactgtttc gtagccttta gtcttgatta aattcaagtc
    53341 catttcaaaa atcaactgat ttttgaaaac tctgtctcct tcttctacat gactaataaa
    53401 accttgacct tttagctcaa cagtatctaa tccaatatga attagtaact caacaccctc
    53461 atcactcttc aatccaattg cgtgcttagt cggaaaaata tttgtaattt tcccatcaaa
    53521 tggtgcataa accttacctt cacttgggat aatcgctact ccgtctccaa ttagtttatc
    53581 tgaaaatgtt ttatcctgga catcgcttaa cggaatgatt tctcctgata taggagaaaa
    53641 tatcattttt ttatttgaaa ctccagcttt aacttctaaa ttactagaac tctcttcttc
    53701 atcgattcca aatatataag ctaatacaaa ggtaataaca accgaaatga ccgccacaat
    53761 taaagcattt acaatatttg atggtacatc agaataaata aattgaggca acgctatcaa
    53821 agatgggaca gcaaatagat acgctttaac actagtaaga cctgcaaata atcccgctaa
    53881 tccaccacca atcatagctg cataaagcgg ttttttatat tttaaagtca caccatataa
    53941 tgcaggttcg gtaattcctg caagtaaggc tgagaaacct gctgcaaaag caatttgttt
    54001 tgtattatta tttttactct ttaatgcaac agccatcgaa gcagcccctt gagctaagtt
    54061 tgaccctaac attgctggaa gaattaatac gtctggagta gcaatagatg ccgccaaaaa
    54121 aataggtgca aaagcccaat gcattccagt cataacaata aatggcataa tagcaccaag
    54181 aatagctaat gtaagccatc cagctacacc atacatttgc ccaactagat ttgataatcc
    54241 ttcaccaaca attactccaa taggtccgac tacaactaag gcaatacagc ttgatactaa
    54301 taatactagc gtaggttgca aaaaactctt agtaacagct ggtgttaatt tagcaatcat
    54361 tttttcaata tatttcatca accaaaccat aataagaatt ggaacgactg acgaaccata
    54421 actagctggt gtcacaggta caccaaataa actaagagga ttccctgatt gcaccatttg
    54481 aacaaaattt ggatggagaa gtacacctgc tacagacata gctaatgtag atgttacttt
    54541 taatttttgt gatgcagaat aagctaataa cagcggtaag aaataatatg gcgcatcccc
    54601 aaaaaatgtc aaaaaagcaa tagtctgaga atctgattgc aatataccaa gcattggtaa
    54661 aataattacc aagactttca gcatacctcc ccctaacatt gctggaatga ttggagtcat
    54721 ggaaccagcg atatactcaa tgattctttc taaaatattc cctttgtgcc cttgaacaac
    54781 tgaatcggat tcaaaattgc caagtttaac gaattcttta taataattag ctacatcatt
    54841 accaagtata atttgatatt gtccattctt tttcataata cctattacac ctggtatctt
    54901 cttcatatca tcatcattga ctaaattttc atcttttaat tctaatctta aacgtgttac
    54961 acaatgggta actctattga catttttttc acctccaatt acatcgagga ttttttgtac
    55021 cttatcttta taactcatgg tattctccta ttctattaat ctaaattttt tgttaagcga
    55081 cgaatatgag ccatcaaata aactaattca ctagaagtca gcaaataatt gtactcagtt
    55141 tgtataaaca ttgccacctg ttcaccacat tcatattctc taggatattt atttttcatt
    55201 aatgctaaca agtcttcatc atcatcgtca caataagttg tattttcaac caagcgatgg
    55261 gcaaataatt ttatatgagt tatgaatcta taataatcaa tagaatcttg gttaaactca
    55321 gtacaataga aatcttgaat gattttctca attcccataa ttatttcagt gattttatac
    55381 gactcttgaa aattattttc taaattagca ttaacaaaat gtagcgctat gaatgcagct
    55441 tcgtcaattg gaagttcaat acctaactct ttttttatta tttgtaaagc ccttttccca
    55501 agttcaaatt cttctttata atatttcgat atttcccagc gtaggggatt cgaaataata
    55561 atcccttctt tataacgttc tatgctcgaa gaaatatgat ccgttaaatt aatatagata
    55621 atttcatcaa aattattacc caatgttatt ttacctaggt taattatttt ttcggtgatg
    55681 tacaccaact ccaaaggaac gttaataaac atctctgtaa aacgggtcat attatctcta
    55741 tttttgagaa aaaaactttt ctcaatatca attggattta ctttatctcc agtttttctt
    55801 ccaaaagcta tgccccttcc aaaaagaaga atatcgatat cttttttact ttgcgcaatt
    55861 acggcattgt ggtttagtat tcgttttatg atcataaaat ttccctttta aaataaaagg
    55921 aacctactta aaaacatcaa gaaacttctt ccgatgtgat taaataggtt cctgctcact
    55981 tgtattagtg ataacatcct tttatttcaa tttttaatgg tgacatgaag cttaaataat
    56041 taataactct gtaaccattt tcattttatg atatttcaat ctatttgtca agtacttgta
    56101 gaaatttttt tattttgtgt gattcgaatg tgataatggc aacagtctca ctaaagaaat
    56161 gaaaatcata catagaaatt tttaaaaatt ttctctatcg taaacctgcc actagttcag
    56221 aagctatact agctgattcc aaacgtaata tggtcatctc atctaccttc cctaataatg
    56281 gcattgcacc ataccaaaca atagtcttat tcaccaaaag aataggcgtt actatttttg
    56341 attgagtaaa agacacttta attttctggc tcttcaactg tgaactacac cccaaaagtt
    56401 agacagaaaa aatctaactt ttggggtgtt ttattatgaa actaacttat g
//
LOCUS       DBEJZV010000012        54978 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.12, whole genome shotgun sequence.
ACCESSION   DBEJZV010000012 DBEJZV010000000
VERSION     DBEJZV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 54978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54978
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.12"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..164)
                     /gene="tnpB"
                     /locus_tag="ACL3S0_000877"
     CDS             complement(<1..164)
                     /gene="tnpB"
                     /locus_tag="ACL3S0_000877"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR1311818.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDR"
     gene            complement(145..330)
                     /locus_tag="ACL3S0_000878"
     CDS             complement(145..330)
                     /locus_tag="ACL3S0_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311819.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(634..2196)
                     /gene="guaA"
                     /locus_tag="ACL3S0_000879"
     CDS             complement(634..2196)
                     /gene="guaA"
                     /locus_tag="ACL3S0_000879"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGR1311820.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2338..3036
                     /locus_tag="ACL3S0_000880"
     CDS             2338..3036
                     /locus_tag="ACL3S0_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR1311821.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3079..3975)
                     /locus_tag="ACL3S0_000881"
     CDS             complement(3079..3975)
                     /locus_tag="ACL3S0_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR1311822.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(3984..4919)
                     /locus_tag="ACL3S0_000882"
     CDS             complement(3984..4919)
                     /locus_tag="ACL3S0_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGR1311823.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4916..5641)
                     /locus_tag="ACL3S0_000883"
     CDS             complement(4916..5641)
                     /locus_tag="ACL3S0_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGR1311824.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5725..6360)
                     /locus_tag="ACL3S0_000884"
     CDS             complement(5725..6360)
                     /locus_tag="ACL3S0_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGR1311825.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(6362..7189)
                     /locus_tag="ACL3S0_000885"
     CDS             complement(6362..7189)
                     /locus_tag="ACL3S0_000885"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR1311826.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7211..7546)
                     /locus_tag="ACL3S0_000886"
     CDS             complement(7211..7546)
                     /locus_tag="ACL3S0_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HGR1311827.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7547..8137)
                     /locus_tag="ACL3S0_000887"
     CDS             complement(7547..8137)
                     /locus_tag="ACL3S0_000887"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGR1311828.1"
                     /translation="MGDFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNH
                     ILDSQIEGVISTADIIEKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNG
                     IEQYISQEDYNRYLSYLNEDKIKVEIERAEKEADITIIMLQMGVEYRLEPTEEQKALY
                     HKMIDLGADIIFGGHPHVVEPSETVEKDGDKKLIIY"
     gene            complement(8153..8275)
                     /locus_tag="ACL3S0_000888"
     CDS             complement(8153..8275)
                     /locus_tag="ACL3S0_000888"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311829.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQGD"
     gene            8788..9399
                     /gene="def"
                     /locus_tag="ACL3S0_000889"
     CDS             8788..9399
                     /gene="def"
                     /locus_tag="ACL3S0_000889"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR1311830.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9444..10172
                     /gene="rlmB"
                     /locus_tag="ACL3S0_000890"
     CDS             9444..10172
                     /gene="rlmB"
                     /locus_tag="ACL3S0_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGR1311831.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10211..11122)
                     /gene="trxB"
                     /locus_tag="ACL3S0_000891"
     CDS             complement(10211..11122)
                     /gene="trxB"
                     /locus_tag="ACL3S0_000891"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGR1311832.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLIVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11188..11412)
                     /locus_tag="ACL3S0_000892"
     CDS             complement(11188..11412)
                     /locus_tag="ACL3S0_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGR1311833.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11490..12233)
                     /locus_tag="ACL3S0_000893"
     CDS             complement(11490..12233)
                     /locus_tag="ACL3S0_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR1311834.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12233..13033)
                     /locus_tag="ACL3S0_000894"
     CDS             complement(12233..13033)
                     /locus_tag="ACL3S0_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1311835.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13191..13547)
                     /locus_tag="ACL3S0_000895"
     CDS             complement(13191..13547)
                     /locus_tag="ACL3S0_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR1311836.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13560..14072)
                     /locus_tag="ACL3S0_000896"
     CDS             complement(13560..14072)
                     /locus_tag="ACL3S0_000896"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGR1311837.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(14072..14566)
                     /locus_tag="ACL3S0_000897"
     CDS             complement(14072..14566)
                     /locus_tag="ACL3S0_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR1311838.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14701..15147
                     /locus_tag="ACL3S0_000898"
     CDS             14701..15147
                     /locus_tag="ACL3S0_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGR1311839.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15144..15791
                     /locus_tag="ACL3S0_000899"
     CDS             15144..15791
                     /locus_tag="ACL3S0_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGR1311840.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLVIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15812..16393)
                     /gene="pdxT"
                     /locus_tag="ACL3S0_000900"
     CDS             complement(15812..16393)
                     /gene="pdxT"
                     /locus_tag="ACL3S0_000900"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGR1311841.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16394..17269)
                     /gene="pdxS"
                     /locus_tag="ACL3S0_000901"
     CDS             complement(16394..17269)
                     /gene="pdxS"
                     /locus_tag="ACL3S0_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGR1311842.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17421..18800)
                     /gene="nox"
                     /locus_tag="ACL3S0_000902"
     CDS             complement(17421..18800)
                     /gene="nox"
                     /locus_tag="ACL3S0_000902"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGR1311843.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19094..20017
                     /locus_tag="ACL3S0_000903"
     CDS             19094..20017
                     /locus_tag="ACL3S0_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGR1311844.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            20077..20682
                     /locus_tag="ACL3S0_000904"
     CDS             20077..20682
                     /locus_tag="ACL3S0_000904"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR1311845.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20700..21944
                     /locus_tag="ACL3S0_000905"
     CDS             20700..21944
                     /locus_tag="ACL3S0_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGR1311846.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22040..22297)
                     /locus_tag="ACL3S0_000906"
     CDS             complement(22040..22297)
                     /locus_tag="ACL3S0_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGR1311847.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22339..24375)
                     /gene="glyS"
                     /locus_tag="ACL3S0_000907"
     CDS             complement(22339..24375)
                     /gene="glyS"
                     /locus_tag="ACL3S0_000907"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGR1311848.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24587..25504)
                     /gene="glyQ"
                     /locus_tag="ACL3S0_000908"
     CDS             complement(24587..25504)
                     /gene="glyQ"
                     /locus_tag="ACL3S0_000908"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGR1311849.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(25872..26633)
                     /locus_tag="ACL3S0_000909"
     CDS             complement(25872..26633)
                     /locus_tag="ACL3S0_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR1311850.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(26906..27748)
                     /locus_tag="ACL3S0_000910"
     CDS             complement(26906..27748)
                     /locus_tag="ACL3S0_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGR1311851.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(27862..29253)
                     /gene="pgdA"
                     /locus_tag="ACL3S0_000911"
     CDS             complement(27862..29253)
                     /gene="pgdA"
                     /locus_tag="ACL3S0_000911"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGR1311852.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDVSKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(29491..29859)
                     /locus_tag="ACL3S0_000912"
                     /pseudo
     CDS             complement(29491..29859)
                     /locus_tag="ACL3S0_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            30116..31093
                     /locus_tag="ACL3S0_000913"
     CDS             30116..31093
                     /locus_tag="ACL3S0_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR1311853.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFADHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            31090..32172
                     /locus_tag="ACL3S0_000914"
     CDS             31090..32172
                     /locus_tag="ACL3S0_000914"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR1311854.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(32236..33271)
                     /locus_tag="ACL3S0_000915"
                     /pseudo
     CDS             complement(32236..33271)
                     /locus_tag="ACL3S0_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(33655..34851)
                     /gene="tuf"
                     /locus_tag="ACL3S0_000916"
     CDS             complement(33655..34851)
                     /gene="tuf"
                     /locus_tag="ACL3S0_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR1311855.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(35773..36642)
                     /gene="gla"
                     /locus_tag="ACL3S0_000917"
     CDS             complement(35773..36642)
                     /gene="gla"
                     /locus_tag="ACL3S0_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGR1311856.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(36865..37386)
                     /locus_tag="ACL3S0_000918"
     CDS             complement(36865..37386)
                     /locus_tag="ACL3S0_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR1311857.1"
                     /translation="MVPKTVTSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAS
                     LGLGFFKKKEDEK"
     gene            complement(37368..38423)
                     /locus_tag="ACL3S0_000919"
     CDS             complement(37368..38423)
                     /locus_tag="ACL3S0_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGR1311858.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVIEKIIPKLNIPEEEKKKKTSELAE
                     LISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNVTDKKLSSMT
                     TTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKEGSQEKL
                     AESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAYQKTVQQ
                     LTITTVRMLRKQWFPKQ"
     gene            complement(38534..38788)
                     /locus_tag="ACL3S0_000920"
     CDS             complement(38534..38788)
                     /locus_tag="ACL3S0_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311859.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(38782..39024)
                     /locus_tag="ACL3S0_000921"
     CDS             complement(38782..39024)
                     /locus_tag="ACL3S0_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311860.1"
                     /translation="MVQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNCVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(39128..39973)
                     /locus_tag="ACL3S0_000922"
                     /pseudo
     CDS             complement(39128..39973)
                     /locus_tag="ACL3S0_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078372828.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            40207..41925
                     /locus_tag="ACL3S0_000923"
     CDS             40207..41925
                     /locus_tag="ACL3S0_000923"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGR1311861.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENTALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            42036..42383
                     /locus_tag="ACL3S0_000924"
     CDS             42036..42383
                     /locus_tag="ACL3S0_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR1311862.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(42661..43497)
                     /locus_tag="ACL3S0_000925"
     CDS             complement(42661..43497)
                     /locus_tag="ACL3S0_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1311863.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(43510..44139)
                     /locus_tag="ACL3S0_000926"
     CDS             complement(43510..44139)
                     /locus_tag="ACL3S0_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR1311864.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(44149..44790)
                     /locus_tag="ACL3S0_000927"
     CDS             complement(44149..44790)
                     /locus_tag="ACL3S0_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1311865.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(44936..46165)
                     /locus_tag="ACL3S0_000928"
     CDS             complement(44936..46165)
                     /locus_tag="ACL3S0_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311866.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSNLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KVDLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(46155..47321)
                     /locus_tag="ACL3S0_000929"
     CDS             complement(46155..47321)
                     /locus_tag="ACL3S0_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGR1311867.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            47465..48478
                     /locus_tag="ACL3S0_000930"
     CDS             47465..48478
                     /locus_tag="ACL3S0_000930"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGR1311868.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(48523..48942)
                     /locus_tag="ACL3S0_000931"
     CDS             complement(48523..48942)
                     /locus_tag="ACL3S0_000931"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGR1311869.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(48953..50359)
                     /gene="atpD"
                     /locus_tag="ACL3S0_000932"
     CDS             complement(48953..50359)
                     /gene="atpD"
                     /locus_tag="ACL3S0_000932"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGR1311870.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(50445..51323)
                     /locus_tag="ACL3S0_000933"
     CDS             complement(50445..51323)
                     /locus_tag="ACL3S0_000933"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGR1311871.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(51339..52844)
                     /gene="atpA"
                     /locus_tag="ACL3S0_000934"
     CDS             complement(51339..52844)
                     /gene="atpA"
                     /locus_tag="ACL3S0_000934"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGR1311872.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(52859..53395)
                     /locus_tag="ACL3S0_000935"
     CDS             complement(52859..53395)
                     /locus_tag="ACL3S0_000935"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGR1311873.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(53395..53889)
                     /gene="atpF"
                     /locus_tag="ACL3S0_000936"
     CDS             complement(53395..53889)
                     /gene="atpF"
                     /locus_tag="ACL3S0_000936"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGR1311874.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(53903..54619)
                     /gene="atpB"
                     /locus_tag="ACL3S0_000937"
     CDS             complement(53903..54619)
                     /gene="atpB"
                     /locus_tag="ACL3S0_000937"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGR1311875.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(54654..54854)
                     /locus_tag="ACL3S0_000938"
     CDS             complement(54654..54854)
                     /locus_tag="ACL3S0_000938"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGR1311876.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT        16332 a        12130 c         9949 g        16567 t
ORIGIN      
        1 aagcggtctt tacgtccacc acaaaagaga aaaacttgac cggagaaagg atccaattca
       61 aagtgggttt taaccagata agccagtgaa tcgattcctt gtctcatatc agtcttccca
      121 cacacgagat agacctgccc taggctagat agatgaattg tcatagagca acaccttatc
      181 caaaagctgt tctaccattt cgagattgag agattgaaaa aaacttactt caagcttgcc
      241 aatacgaatt ttaagcagaa tatcatttct ctttttagaa tcaaaaggac gagattgtgg
      301 aatctctaca ggaacaatag gttgtggcat taaaatatcc tccaatagtt ttactttact
      361 aatagtatac aggaggaact ccatgaatga tagatacctt gttatgacgc gcttactata
      421 ttagaaagtt ggctctctaa ttaaattaat tctcattata tatatcaaaa gaccgcagtt
      481 tgaaaactac ggtctaattt tttgtccaaa tgtaaatcac ttggaactat tattcaattt
      541 attcttttta gtaaatgttc ccgttttaat cccagttaca gtttttaatc ctctgtaacc
      601 gttgatttta caaagctttt aatttttttg cgattactcc cactcaactg ttgcaggtgg
      661 tttacttgta atatcgtaga cgatacggtt aacatgatcc acttcattta cgatacgcac
      721 tgagattttt tgaagtactt cccatggaat tttggcaaaa tcagcagtca taccatcgat
      781 agaagtgata gcacggattg caatcgtgta gtcatacgta cgaccgtcac ccataacacc
      841 gactgaacga acgcctgtgt taacagtgaa gtattgccaa atatcgcggt caagtccagc
      901 tttagcgatt tcttcacgaa gaatagcgtc tgattcacga acggtttcaa gtttctcttc
      961 agtgatttca cccatgacac ggatagcaag tcctggtcct gggaatggtt ggcgccatac
     1021 gatatggtct ggcataccaa gctctgtacc aagagcacga acttcatcct tgtaaagagt
     1081 attgagtggt tcaatcaatt caaactgcat atcttctgga agaccaccca cgttgtggtg
     1141 tgacttgata gtttgagctg tatccgtacc agactcgata acatctgtat ataaagtacc
     1201 ttgagcaagg aatttcacat ctttgagctt gcttgcttcg tcatcgaata catagacaaa
     1261 ctcgttacca atgattttac gtttttgttc aggatcagaa acgccagcaa gtttgtcaag
     1321 gaaacgttta gcagcgtctg ctttgacgat attcaaacca aacttaccac cgagcatgtc
     1381 cataacttga tcagcttcgc ctttacgaag aagaccgtgg tctacgaaga tacagatcaa
     1441 ttgatcgcca atcgcttttt ggagaagaac cccaacgaca gatgagtcaa caccacctga
     1501 tagaccaaga aggacacgtt tatcaccgac ggtttcacga atttttttga tctgcatgtc
     1561 aatgaaatta tccattgacc agtcaccttt agccttacaa atgttaaggg caaagttacg
     1621 aaggatatca tttccgtata cagaatgacg aacttctggg tggaattgga taccgtaaat
     1681 gtgtttatct gggttttcga tggctgcgta tgggcagtca gctgatgtac ctgtacgaac
     1741 aaagtcagca ggaatctcag taaccgcatc accatggctc atcaaaacag tctgttcatc
     1801 aggtgttgat tcaaaaagcg ctgatggtgt gtgagttagg gttgattgac cgtattcacg
     1861 atttccagca tcacctgcag gaacaacttt tcctccaagt ttatgggtca ataactgcat
     1921 accataacag attcccaaaa ttggaattcc gagttcgaag atttctgggt caatatcaaa
     1981 tgaaccatct tcatatacag aatttggacc acctgataga ataattccta caggattgac
     2041 ttcacgaact tcagcagctg aaattttatg gctttttagt tctgaaaaaa caccaatctc
     2101 acggatacgg cgtgaaatca gctggttgta ctggctacca tagtccaata cgatgatttt
     2161 ttctacatct tgcaaatcag ttgaaatgtt gctcatcttt ttcctttctc aaaagaaata
     2221 tcttttctca atattctatc acaaataagg gcgaattacc aactaaacaa ggcgaagttt
     2281 gactttttct agtttattgg ggtacaatag agaaaagata gaaatgaagt gaaaaatatg
     2341 ctacctgctt atatgaaaat ccatgatcag ataaaaaagg atattgacga gcaccgttgg
     2401 gctattggtg agaggcttcc cagtgaaaga gatttagctg agcagtttgc ggtcagtcgc
     2461 atgaccctcc gccaagccgt atctctatta gtcgaagaag gcgtcttaga gcgccgtgta
     2521 ggaagcggca cctttgtttc cagtactcga gtacaagaaa agatgcgagg gacaaccagt
     2581 tttactgaaa ttgtcaaatc ccaaggtaaa gttccctcta gccagctcat ttcctacaaa
     2641 aaaaccattc ccaatgagca agaagttgcc aagctaggaa tttttccaac ggacaatatt
     2701 atccgaatgg agcgggtccg ctatgccgac caagttcccc tagtttatga agttgcttct
     2761 attcctgaaa aattcattaa ggactttaaa aaagaagaaa tcaccagtca tttcttccaa
     2821 accttgcaaa aacatggcta tcgtatcggt aaatcccaac agaccatcta tgctcgcctt
     2881 gctaaagaaa agattgccca ctatttggaa gttgaaaaag gacatgctat tcttggattg
     2941 acccagattt cctacctaga agatggtact gcttttgaat acgtaaaaag tcaatatgta
     3001 ggcgaacgct ttgaatttta tcttgaaaat aattagatta ccacgcaaaa actctctgtc
     3061 acggacaaag agtctttttt atttttctaa gaataaatct ttcaaagaaa tcaaagttac
     3121 agcaaacaat atcattgcca taccaagaaa atcaatggga taaaattgtt cattcattat
     3181 taagaaggca aagaaaatcg ccgatattgg ctcaattgaa gccaacaagc ttgacttgac
     3241 cggtcctatc agactggctc ctttaaggaa agctgtatag gcaaagacag tcccgataag
     3301 gataatgcct gcaaacgcaa ggagaaaatc aagactagtc gggatatcgg cctgtagaac
     3361 ccctgtaaaa ggaagggcga ccaaacctgc tatgaccatt cccacaccaa tgaccaagct
     3421 gctcccccac tttttaatca aggctatggg taaaatgata tacagagcat aagtcaaggc
     3481 agaaaagaga ccccagaaca gaccagcagg tgtcatggat aactggtcca actgcccatg
     3541 tgttgcgatc aggaaggttc ctccgatggc gaatatgatg gaaactatct ctcccagtgt
     3601 cggtgccacc ctatccttga tacagctata aattaaaatt ccgacaggac aaacatactg
     3661 aagcaccgtc gctgttcccg cattggtctc ctgaatagca gacagatagg cgaattggtt
     3721 gagaaaaaga ccaatcagag caaaaataag aagagacagc aaactctttc tatcctttaa
     3781 aaagaccagt attttatcct ttgcagtagc ataagccaag agcatgagaa ttccaccagc
     3841 gattaaaaga cgcaagttag tcaagaccag agccgaaatt ccgtgtgcca ttaggtattg
     3901 gccactcgtt cctgacaacc cccaagcaat accagccaca actgttagta aagtcccttt
     3961 taaactattt gacatgtctc tccttactct tctttgcgaa tcaagttcat cacttgattg
     4021 cggtctaata tccattgagc tctctcgtcc ttttcatagg tacgattcga taggaaaata
     4081 gtggcttctt gcttctgacg attccacatg ataaaggtac ctgtatagcc cgtatggtct
     4141 agccaatctc cttccaaatt ccatgctaaa gaacgttcct tgtcatccaa aggagaaaaa
     4201 ttttgattta agtctcttgc aaaatcatct gctaaatagt gttctaaaaa gatttgtaaa
     4261 tcctttatag tcgaaaataa accagcactc ccagcatgtc tacccaggag acgagccttg
     4321 ggatcatgca ctatgcctgc ctctacacct ctaactgttg gaacagcaag ctcaactggc
     4381 ccaaacttgg tttccgtcat tccccaaggt ttccagactt gatcctttaa aatcacatcc
     4441 aaatcttgat taaaaattct ttccaaaata aagcccaaca gcaaaaaatg gacatccgaa
     4501 taaagaaagg ctggctgact tcgtctgttg agatgaaaca tcgcttcctt taattcaggg
     4561 gctgttaaaa gatcacgatt aggaataaaa ggatcaaggt ctgttgcatg agtcaagagc
     4621 tggcgaatag tgatgtctgg ataatcactc tcaggtaaaa aatctattac cagtctatca
     4681 atatctaatt gacctatttc ccacaagaag gtacaaactg tgccaacccc aacaaccttg
     4741 ctgacactag ctaggtcata aactagtcct gcctcagtct gcaagccatg ctctgggtca
     4801 ctctggccta aatagaactc tgtccattga ttgtccttaa aatacgcaaa agaggctccg
     4861 ggataaatcc ctgcctcgat ttgttcttct atttttttaa taatcttggt ccacttcata
     4921 cttcttcaaa ccacaattca acattatttc tatctttacc aaggaagaat ttttcagact
     4981 taggaataaa atattcagta gactcaaact tctggcgaag acttgctatg tctaattcat
     5041 tgaccaagaa cttgagcata gataagtccc aggtaaccgt attgtccaca gtcaaatcct
     5101 gcccctgagc tggaataaaa tcaagggatg ccccaatttc agatgattcc aagaaacttt
     5161 cgatatcagt tgggagatgt aattccatag aaatctcaaa tttacttaaa gaaattgatg
     5221 ccaaatctgt ttgaaattca ggcttttctc ctacttctac tagacttgct atgtcatctt
     5281 ccgcatgaat caaaatcaaa tcatcttctg gtgagaaaat ttcaaaagcg tagccatttt
     5341 gacctttata taatcgatga atcgaatctg ttttagataa gattccttca atttctaagg
     5401 gattttccac cttgacaatc aatctagcta gtttttttct tccctctacc ttacgagtac
     5461 gcatactggg agcttcttct aaaaccagct tttcaagacc cgtttggtca cctagtgaca
     5521 gaaaggccga ttcttctaac aaggccttca ttccaagggt ttcaatataa aatgtttcat
     5581 ttaattttct attattagct tttaaagtag gaataatccg tacaatctga tttacattca
     5641 taaattcctc cgtcactttt tattttaaag gattttagaa ttttttacaa gatattatgc
     5701 tcaaatttaa cattatttag ctatttagta aagatagtct ttcaaggatt ttgacaaagc
     5761 ctgataacca gcaatactga ggtgcagtcc atcagttgta tattcttttt tgagttggcc
     5821 tgcttggtct gtcaaacaat caaatactgg cacaaattcc acctgcatat aggcagatgc
     5881 aagctcttga taggcttgat tccagttctg aattttttca ttcgagcgga tatagactgc
     5941 ctgctggtac tcctctctct cattgacagg caaaatggaa agcaatttaa tctctgtcaa
     6001 tggataatcg cgagcaacgg attgaatgat agcttcgaga ttattgagag cctcattcac
     6061 aggaacatcc tttccgatat catttgtccc aatcagaaga aaaattttat ctactgctcc
     6121 accatataga tgagcatcaa ggttctctag taacagtcct gtctgatagc cacgaattcc
     6181 tcgattgaca atcgtctttg aagtcccaaa tagctcctgt agaggataat actcgacaat
     6241 ggaatcccca ataaaaagaa tgtttggttc tacaacagaa atgtgattta ggtgacgata
     6301 cttagtttga attttttctt gttcctttag gagccaattt tctaataact gtactgccac
     6361 ttcattctcc tttttctaac cagttttcca agacttgata aactcctcct tggctgttgg
     6421 ctggtgctag agcagtcgcc acagctttgg ctttctcatc agcattttcc atcgcatagg
     6481 caattccagc catttcaagc atttcaacat cattttcact atcaccaaaa gccatgattt
     6541 cttgggattt caagtcccag cgcttgagta attcctccaa gccccatgct ttatgaatcc
     6601 cagcttggag gatatcaatg caaccatagc cactggatac agctcggaca cggccatcaa
     6661 agagagcatt gatttcttcc aaaaccgaac tcaaacgttc ctcaccaaca accatgctca
     6721 tcttgagcac accaccaaag aggtcagatg ttaattcatc cacaaattgc atccgttggt
     6781 agaatttttc aatcatttct ggagtcataa aactttcaag atctgtaaaa atcgtacctt
     6841 ccttgacaaa atcacccttc atccccgtta caacaaactg gtcctgacac gctcgaccct
     6901 tgaaatgagt caaagccttg ttgacaatgg cgtcatccca tgtctgagcc tgaatcaatt
     6961 cattgttttc aaaaatacga gcgccattag caacaaccag aaccactcga tccaccaagg
     7021 gactcagtag ttgtctcatg cggtgaattt cattgcccgt cgcaatgaca aaacgaatgc
     7081 ccctttgatc caactgatct aaaatctttt ccaatcgtgg gagatcaagc tgacctctag
     7141 catccagcaa ggtcccatcc atatctgtcg caattacctt aatcatcatt tactttcctc
     7201 tggattcaag ctaataccac ttcaatccca catgttcatt catttcttta taggctgtat
     7261 caattcgttc cttagtcgct tcatctaact ggtcacgatg actgccatcc tctataaaat
     7321 cttccaaaat ataagtttgg taatgataca agggatatcc ttctggtgaa aaggttccct
     7381 ttggtgttcg attgacccaa gtaggatgag ctttagctgt tccgatagtt gtttttccat
     7441 ccttcttctt gatggtgaca tccatgagaa caccacgttc agtccactta gcattctctt
     7501 catctcccat agattcaatt cgttgattgg aaatgaagtt ccccatttaa tagataatga
     7561 gtttcttatc tccatctttt tcaaccgttt cagatggttc aacaacgtga ggatgccctc
     7621 caaagataat atccgctccc aaatcgatca tcttgtgata aagagctttt tgttcttcag
     7681 ttggttccaa tcgatactca acacccatct gaagcatgat aatggtgata tctgcttcct
     7741 tctctgcccg ttcaatttca acctttatct tatcttcgtt taaatatgaa agataacgat
     7801 tatagtcttc ctgagaaata tactgctcaa ttccattgaa accataggaa taggctaaca
     7861 atgcaacctt gataccattc acttccttaa tgaccagcgg agcctgatca cgtggttcgt
     7921 gcgtataaac tccgattgga gtgattccag ctttctcaat aatatcggcc gttgaaataa
     7981 ctccctcaat ttgcgaatcc aaaatatgat tatgagctaa atccagcaca tgataacctg
     8041 cctccttaat agcatccata acttcaacag gagcattaaa gagaagataa cccgctaaat
     8101 aatgatcctt attaatggtt ccttcaaaat caccaatagc taaatctgct gcttagtccc
     8161 cttgcttgag ccaaggagtc acatactcaa aattttcatg aaagtcatag gtaccgtctt
     8221 cttttttagc tgaaaagaaa agtccatcgt ggtagagcaa atccccgtgg gccataattc
     8281 tggcagtttt ttcctcttcc tactcctgag acttttgctt agtcccctct tgagaaatag
     8341 tatctcgttt ttgactagtc aagggattcc ttggaagctt tcaaacaaca agaccaagcc
     8401 cattgataaa ccaactgcta gcaagagtat cgccacaaat cccttattgc tccacttgcg
     8461 ataactccta aaaagtttac caagcccttc ataaaacgaa aagctaaacc accctgattt
     8521 cgattttgtc ttctttgtat cttcgttctc cctactttct tatgcaagcc ttttcttttt
     8581 attatatcac agataagtat ttctttcaca attgaattga acttcccatc tattttctat
     8641 aaatcctaaa tgccataatg ctttcaattc ttgtcatttt gtgatatcat gtagaggaaa
     8701 tgaactaatc cacagtggct tattccaagt ataccacttg ggctttggca gtagctaact
     8761 gcactaaaca taatataagg agagaaaatg tctgcaatag aacgtattac aaaagctgct
     8821 cacttaattg atatgaacga tattatccgt gaagggaatc ctactctacg cacggttgct
     8881 gaggaagtca ctttccccct atctgaccag gaaatcatcc taggcgaaaa gatgatgcaa
     8941 ttccttaaac attcccaaga tcctgtcatg gctgaaaaaa tgggactccg cggtggtgtt
     9001 ggactggctg ctccccagtt agatatctca aaacgcatta tcgctgtttt ggtacctaat
     9061 attgttgaag aaggcgaaac tccacaggaa gcctacgatt tggaagccat tatgtacaat
     9121 ccaaaaatcg tctctcactc tgttcaagat gctgctcttg gcgaaggaga aggttgcctg
     9181 tctgttgacc gtaacgtgcc tggctatgtt gttcgccatg cccgcgttac tgttgactac
     9241 tttgacaaag atggagaaaa acaccgtatc aaactcaaag gctacaactc cattgttgtt
     9301 cagcatgaaa ttgaccacat taacggtatc atgttttacg atcgcatcaa tgaaaaagac
     9361 ccatttgcag ttaaagatgg tttactgatt cttgaataaa gaaaatcccg ttgcaagacg
     9421 gggttttgtg ttataataga ggcatgaaaa caaatgatat tgtctatggt gtccacgccg
     9481 ttaccgaagc tctccttgca aatacaggaa acaaactcta cctccaagaa gatctccgag
     9541 gtaagaatgt tgagaaagtc aaggaactag ctacagaaaa gaaggtgtcc atttcttgga
     9601 catcaaaaaa atctctctct gagatgactg aaggtgctgt tcatcaaggt tttgttctac
     9661 gagtgtctga atttgcctat agcgagctag attacatcct tgcaaaaaca cgccaagaag
     9721 aaaatccact tctattgatt ctagatggtc taaccgatcc ccataatctg ggttctatct
     9781 tgcgaacagc cgatgcgacc aatgtttcag gtgtcatcat tcccaagcac cgtgctgtcg
     9841 gagtaactcc tgtcgttgcc aaaacagcca caggtgctat tgaacacgtt ccaattgccc
     9901 gagtgacaaa cctcagtcaa accttagata aactcaagga tgaaggcttc tggacctttg
     9961 gaacggatat gaacggtact ccttgccaca agtggaatac aaaagggaaa atcgccctca
    10021 tcattggaaa tgaaggaaaa ggtatctcta gcaacatcaa aaaacaagtc gatgagatga
    10081 ttaccattcc gatgaatgga catgttcaaa gccttaatgc cagtgttgct gcggccattc
    10141 tcatgtacga agttttccga aatagactat aaaaaagttt ccagtcatct gattggaaac
    10201 ttttttatga ttaactatgt tctgtgataa acttgtaggc ttcttgacca gcgatagctc
    10261 catctccaac tgctgttgtt acttggcgaa ggtctttcaa gcgaacatct ccaactgcaa
    10321 agataccgtc gactgcagtc ttcatgtggc tatctgtcac aatccagcct gcctgatctt
    10381 ggatattcaa ttctttaaca aaatcgctaa gagggtccaa accaacatag ataaagacac
    10441 caccgaaggc ttgttctgtc acttgacctg ttttcacatt ttcaaatacg actgattcta
    10501 ctcggttttc acccttgatt tcccttacta cagaatccca gataaagctg attttttcat
    10561 tcgcaaaggc gcgatcttgt aaaacctttt gggcacgaag ttggtcacga cggtgaacaa
    10621 tggtaacagt cttagcaaaa cgagtcaaga agagggcttc ttcaacagct gaatctccac
    10681 caccaactat caataaatct tggtcacgga agaaagcacc atcacacaca gcacagtaag
    10741 aaacaccacg actgttcagt tcttcttctc caggcactcc caaaggacgg tgtttagaac
    10801 cagttgctac gataactgta cgtgtttcat atgtttggtc atcagtcatc actttcttaa
    10861 aatcaccatg gtcttcgaca ttttcaacat aaccataaat gtgctcaaca ccaagatttt
    10921 caagtggttc aaacatcttt tcagccaatt caggtccact aatattagcg tatcctgggt
    10981 aattttcgat atcagatgta ttattcatct gaccacctgg cagaccacct tcaatcaaag
    11041 ctacttttag attgcttcga gcagcataca aggccgcagt catccctgca ggtccagcac
    11101 cgataataat agtatcgtac atatagattc cttctttctt gttgtaacta tctttattct
    11161 aactctttct tgtcaatcac gcaaggatta tgccttgaaa acaagaatta aactcataac
    11221 cgcaaaggat aatactggga caaccaagac tccaatcata atcatatcat agagatgggc
    11281 ttggcgagcc ttggctgtct tatcaactcc cgacatggct ctcagaccaa tccaaatccc
    11341 taaaaaaatc agaacaagga tggtggtcaa tatcaaactc tcgaaatata aagaaaatag
    11401 ttgcagtagc atgatttctc tcatttctat cttttttaaa gagtaaactc agctagtcca
    11461 actaactgag ttttccttta tctattatat caaatataag tccgtttgta actagcgaag
    11521 aattcttttg tccgctcttc tttaggggtg tggataatct catccggagt tccagactcg
    11581 atgattttcc ccttatctaa gaagagaatc ttatccgcaa cttgggctac aaaggacatg
    11641 tcatgactga ccaaaatcat ggtctgacct gacttagcag catctgcaat agacttttct
    11701 acttcaccga ccaattctgg gtcaagggct gaagttggtt cgtctaagag caaaacatct
    11761 ggtttcatag caagcgcacg cgctagggca acccgttgct tctgtccacc tgataaatgg
    11821 cgaggataat ggttttcacg gtccgaaagc ccaaccttag ccaactcttc cttggcaatc
    11881 ttagtcgctt cttggtcaga taatttcttg acaacaacca agccttcttt cacattatca
    11941 agtgctgttc ggcgttcaaa caaattaaac tgttggaaaa ccatagacaa cttacggcgt
    12001 agggcaagga tttcttcttg agtgatttta gaaaaatcaa ctgaaaaacc atcaatctga
    12061 atagagccac tgtcaggtgt ttcaagataa ttgagactgc gaagaaaggt tgattttcca
    12121 gctcctgaag aaccaatcaa ggctacaact tccccttttt gaatatccaa gtccagatga
    12181 tccaagacag tctgtcctga aaaggatttg cttaaattcg aaatcttaat cattaacgaa
    12241 ggtctccttt cacatctgtt tgcactgtat caggtgcaga aatagccatt tttctctcga
    12301 tgaaacgacc gaggctttca attccgatat tgactaccca ataaacaagg gcaacggaga
    12361 tgaagcgttc aaaatagcga taatcagctc cacctagaat ctgagcttgg gcaaagactt
    12421 ccacaacacc cgcactaaaa gctagagatg ttcccttggt caaaccgatg agggaattaa
    12481 tcaaggttgg agtagctacc accgctgcat taggaataat cactcgtcga taaacttgcg
    12541 ctcgggtcat acccagactg cgtgccgcct caatctcacc aggattaact gagagaatgg
    12601 ctgcacgaat ggtttcacta gcataagctg cctcattaaa ggcaaaagcg acaatcgcaa
    12661 aagctgcagc tggaatcgca ttgatattga gaccagttcc ccattgctga ttgagggctt
    12721 tcaaagccaa agggattccg tagtaggtca acatgagttg caccaaaatc ggtgtccctt
    12781 ttaagaaact aacaaagaag gcctgcaagg gatataaaat cttgacacga ttgatcttca
    12841 caatggcaaa aagaagcgcc aaaaccaagc caaaaagggc accaccaatt gtcaacataa
    12901 ttgttgttgg aagttgttgg acaattctag ggattccatc aaagaccgaa cgtaggctaa
    12961 acagcttgcc atccggaatc aattgcatca agttttggta ccaatctgat gctaaaatcg
    13021 ttgtaacatt cataaaaaca tcctcttctg ataatgattc attctaccat gcttctgccg
    13081 tcaatgaaat tatttgctac ggtcagatac agactttgtc tacctactag tttatcatac
    13141 tttgaaacag ggaagttata tattttatct atcaaagaga tagataaaaa ctatttcagt
    13201 cccagttctt cataagattt tcgataaccg atttgcttaa cagttccatt ttctactaaa
    13261 atgggccgtt ttaacaacat accgtcactt gctagcaact cagccgcttc ttggtttgac
    13321 aaacttccta ccttatcttt tagccctaat tcacggtatt tgataccact ggtgttgaaa
    13381 aattgcttca attcaaatcc tgaggtttct agccaattca aaatgacttc ttggctaggt
    13441 gtttcttcca cgatatggac ggctttatag tccacaccta attgatttaa ttcttgtttt
    13501 gcttttttac aagttgaaca tttggggtat tcgataaatt ctaacatgtg cttctccttc
    13561 tatttgttta tatctttaaa atctacgcct tcatgctcca agagccaagc tttcttttcc
    13621 actcctgcag catagcctgt cagacgcttg cctgctccca acacacgatg acaaggtact
    13681 aggatagacc aaggattgcg tcccactgct ccaccaattg cttgagcaga agccacttgc
    13741 aggtcttgag caatttgtcc ataggtcact gtctgaccat aaggaatgcc ctgtaaatag
    13801 tcccaaactc tcttttcaaa attcgttccg attggcgcca agagcaagtt ggataaatcc
    13861 tgaggcttgc ctttaaagta atcatctaag caagcaataa ctgggtctaa aataggatga
    13921 ctaacaactt cttctatcgt ttcatctcct agtcccctct caaaatgctt ctgctcctga
    13981 acccaaattc catacaaata atggtcatca gctacaagtg atagaatacc aattggtgag
    14041 gagtagagta tttttacata cttcttttgc attatttctt taatttttga taggccaagc
    14101 gttcgccatc tactggcacc ttaccaactt gtttaaaacc aagtttttca aaaatatgtt
    14161 gcataacctt gttttcagca tgcgtatctg agcgaaaatc aagataatca aaaccttcaa
    14221 tcaagccctc taagaaggtt tgagcaactc cttttccctg cacatctgct gccacagcaa
    14281 tacggtgaaa gactagatac tctgactctc cagcttgcca gtttccctca taaatagctt
    14341 cataggcctc ctctggactc ttggtcacag cagcataggc tagcagttct ccctcttcca
    14401 aggctacgta ggcttgccct gagatgatat catcgataat aacatctgca tttggatagc
    14461 cattttgcca ctggtcacta ccagcatctg ctaaacattt tttggcatcc tccatcacct
    14521 gcatgatggc atctacttca tttggaaaag ctaaacgaat ttccatcttt tttcctcatt
    14581 tctgactagt ttctcccatc atagcataat ttaagtattt ctacaagcag ttaaaacttg
    14641 actttgtgtt tttgttattt tataatctag ttatcaaaac tatataaaaa ggagttgaaa
    14701 atgaaaacta ccttttccta cccaaaatgg gcagaaattc caaacattga cctctatctg
    14761 gaccaggttt tgctctatgt caatcaggtc tgcgccccta tctctcctaa taaagacaag
    14821 ggcctaacag catctatggt caacaattat gtgaaaaatg gttacctgac aaagcctgac
    14881 aaaaaaaaat accaacgcca acagattgcc cgtttgattg ctatcacaac cctcaagtct
    14941 gtattttcta ttcaagaaat agcccagaca cttaacactc tacaaactca agcaagttca
    15001 gaccaactct acgatgcttt tgtggactat atgaaccaag gaattgaccc agctaaccct
    15061 attatccaaa ccagctgcca aaccgttaaa ctctatcatc aaactctaga cttaatcgat
    15121 catactcaag aggaggtaat ccaatgaaca ctagtcttaa actcagcaaa caactcagtt
    15181 ttggagagga gattgctaat agcgtgaccc atgctgtggg tgcagtcatc atgcttatct
    15241 tgctgcctat ttcatccatc tatagttatg aagcacacgg atttttatcc tctatcggcg
    15301 tttccatttt cgtcatcagt ctctttctca tgttcctatc atccaccatt tatcactcta
    15361 tggcctatgg ttcgacccac aaatatgttt tgcgaatcat tgaccattct atgatttacg
    15421 ttgccattgc cggctcatac acgcccgttg tcttgacctt gatgaataac tggtttggct
    15481 atctgattat tgtcatccaa tggggaacga ccatctttgg tattctctat aaaatctttg
    15541 ctaaaaaggt caatgagaaa tttagccttg ctctttacct gattatgggc tggttggttc
    15601 tggttatcat tcctgccatt atcagtcaaa cgacacccgt tttctggagt ctcatggtaa
    15661 ctggcggact ctgttataca gttggagctg gattttatgc caagaaaaaa ccttatttcc
    15721 acatgatttg gcatctcttt atcctagctg cgtccgcact tcaatacatc gctattgttt
    15781 attacatgta aaaaagttga gaaattcaat ctcaactttt ttctttacac atattgataa
    15841 agtactggtg caagcgcaca tcatcagtca attctggatg aaaagaactt accaacatat
    15901 ttttttcttg ggctgcaaca atttgattgt tcactgttgc taaaatttct acaccctcac
    15961 caacactact gataatcgga ccacggataa aggtcattgg aatcttgcca actcccttac
    16021 attctgcttc cgtgtagaaa cttcctaatt ggcgcccata agcattacgc tcgaccacca
    16081 tatccatagt tcctagatga ctctctttct gagaagtgat ttccttagcc agcaaaatta
    16141 agcccgcaca ggtcccaaac actggtaagc cagatagaat ggcttctcgg atgggaagta
    16201 gcatgttctg gtcacgtaag agcttgccca tggttgtaga ctcaccacca ggcaaaatca
    16261 aacccgacaa gtcactctga tcttgctgaa aatcatctag atttctgagt tctacactct
    16321 cgacacctaa ttgatctagc acttttgcat gttctgcaaa ggccccttgc aaggccaata
    16381 ttccgatttt catctatttt cctcgttcag ccatgagaat ttggatttca ttttcattaa
    16441 taccaaccat ggcttctcct aaatcttcag agatttgagc taggatttga ggattacgga
    16501 agttagtcac agccttaaca atggcactcg ctcgtttaac aggatctcct gacttgaaaa
    16561 tacctgaacc gacaaagacc ccctctgccc ctaattgcat cattaacgca gcatctgctg
    16621 gcgttgcaac acctccagca gcgaaattta caactggcaa ttttccatgt tcatgaacat
    16681 attggaccaa ttctacaggg acttgcaaat ccttggcagc aacataaagc tcgtcctcac
    16741 gtaagttttg aatgcggcga atttcctgat tcatcatacg catatgacga acagcttgga
    16801 cgatatcccc tgtccctggt tctcctttgg tacgaatcat ggaagcacct tcagcgatac
    16861 gacgcaaggc ttcacccaaa tccttagcac cacagacaaa aggaacttgg aattctttct
    16921 tgtccacatg gaaacggtca tcagctggag atagaacttc actctcgtcg atataatcaa
    16981 tttcaatagc ctctaaaatc tgagcttcaa caaaatgccc gattctgacc ttagccatta
    17041 ctggaatact aaccgcttct tggatttcct taatcatctt tgggtcgctc atgcgggaaa
    17101 ctcctccagc tgcacgaata tcagccggaa ttcgttccaa ggccatcaca gctgccgcac
    17161 cagcagcttc tgcgatacga gcctgttcag gattctgcac atccataata acaccaccct
    17221 tgagcatctg tgccaagttt ttatttagtt cataacgatt ttcagtcatt tgttttatcc
    17281 tcatcatttg tattggtagc taccttttca ttttaagtca gaacagaatg aagcacaaga
    17341 taaaaaaact ataattgtat ggggacagat tggctaaaaa ttatctgacc ttaacttaag
    17401 gccagatagc tcattcattt ctatttttca gccgtaaggg cagccattgt gatgtagttg
    17461 tatggtttgt tgaagtgtgg caagaagaag aggtctgtca atgccaattt atcaattgtc
    17521 acatgctctt ggatagcaag tgagaacatg tggattccca tgctaattgc aatatcatgt
    17581 gaaaccattt gggcaccaag aatttcacgg ctatctttgt caaagacaat cttaattgct
    17641 acttcatggt tgtcatgttt catgaattct ggtttttgaa gatcgttaaa gcctgtttca
    17701 gttgcgttgt aaccagcagc tttcgctttt tcaagagtca aaccagttga aaccatgtga
    17761 agaccgtaga ttgagatacc atttgaacct tgaacaccga ttccttccaa ttcatgtcca
    17821 caagcattgt aggcaccaac gataccagtg cgaacagcat ttgaagcaag agcgatatag
    17881 cttgtatctt tacgagcatt gtcataaaca gtcgcacagt caccaacagc gtaaacgcct
    17941 gggatagatg tttcttgttt cttgtctaca aggaaggcac cgttgcggaa gagttcgatc
    18001 ttaccatctg caagggctgt gtttggacgg aaaccaactg caaggataac catatccacg
    18061 tcaaagcttt ctttgtcagt aatcaagcgt tcaactttac cgtcaccttc gattgcttta
    18121 acagtttgac ctagagccaa gcggatgttg tgatcttcca agttcttcgc catcatttgt
    18181 gtgaagtctt tgtcatagta accgttcaag acagtatcaa cgatatcaac aaggacaact
    18241 tcttttccaa gacgttcaaa ggcttcagca agttcaacac cgatgtaacc accaccaaca
    18301 acggcgatac ggtcgaggtg ttggctcttg tcagaaagtt tattgataac ttcttcagca
    18361 ttttggtaca atttcacgaa ttgtacgttt tcaagagttg ctttaaattc gcggtttcct
    18421 ttaacaattt caacaccttc gattggtggc aagattggtg tagaacctgt agcgaaaatc
    18481 aatttttcgt atgattcttt gtgctctttt ccttcaactt ccgctgtaac tactttgtta
    18541 tcatagtcga ttgaaagaac aggtgagttc atgtaaactt tagcaccttt agcttccaat
    18601 ttttctttat cagaatagaa caagccttca gcaccgtcaa tttgttcacc aatccaaaga
    18661 gccattccac atcctaggaa agagatgtta gagttttggt caaatacaac aatttcgttc
    18721 tcatttccaa aattatccaa catggtattg atacatgctg taccagcgtg gttagcaccg
    18781 actacaacga ttttactcat aaaaatttcc tgccttcatt ctaaatttac cttactagta
    18841 taccatttac cgttagcgtt tacaaggggg gtactattat ttcagcattt tttatcaaaa
    18901 ataattcccc atttatcctg ttttcaagcc tgatgaattt tatgagcata tttcttgact
    18961 ttttccaaat tttgtttgtg aaaattctaa ctttatggta ttataataac atgaaaatga
    19021 aatgtaaggg cttcaattta gatgattatt tgatattaca acttattttc tataagagaa
    19081 aggagttggt agcttgactc ttcgttcaca ttctgaacgg ctaatgggga ctactatcac
    19141 tatttcatta gtggatgagc aagccgatat ctttctccaa aaatcctttg acttgctcaa
    19201 agaacttgaa taccgcttca acgccaatag tcaagaatct gagttgatgg aaatcaatta
    19261 tcaagcagga atagcccccg tcacggttca tccagacctg tttgagctga tttcacttgg
    19321 gttagagcat agcctagcgc tctctagcca cctcaatatc agcattggtc ccttaattca
    19381 aacctggcgt atcggttttt cagatgccaa ggtcgcgcag cctcaagaaa ttgaatcggt
    19441 gctgcctcta atcaatcctc atggtatcga gttagattct tctacttcta ctgtgttttt
    19501 aaaacagaaa ggaatgaaga tcgatctagg ttgtttagcc aaaggataca gtgcggataa
    19561 ggttgcccaa tttcttagga aagagggggt gacttctgcc ttgatcaatc tgggagggaa
    19621 tatcctgacc attggaaaaa atcaggcaag aggggataac ccatggcaaa tcgggattca
    19681 agacccagcc aatcctaggg gaaatcattt aatgaccatc cctgttgtca ataaatctgt
    19741 cgtgacttca ggcatttatg aacgtcacct gaccgtcgat ggacaagatt accatcacat
    19801 ttttgacagt caaacaggat atcctgttga aacggaacta gcgagtctaa caatcatctc
    19861 tgataaatca gtcgatggcg aaatctggac gactcgactc tttggagaaa gacctgcttc
    19921 tatcctctgg caagtcgaaa gtttggaggg catcgaagtc atcctcatcg ataaagaagg
    19981 ccacctaagc tgttcttcag gaattcctac tctatagaga caactgtttc aatggaattt
    20041 taaaattgta ttatgtaaaa agagaaagga aatctcatgt taaaacttat tgctattgtt
    20101 ggaacaaatt caaaacgttc tacaaaccgt caattgcttc aatacatgca aaaacacttt
    20161 gctgacaaag ctgaaattga acttgttgaa atcaagacca ttcctgtctt caacaaacca
    20221 gctgacaagc aagtacctgc tgaaatattg gaaattgctg ctaaaatcga agaggcagat
    20281 ggcgttatta tcggtactcc tgagtatgat cactctattc cagctgtttt gatgagcgct
    20341 cttgcttggt tgtcttatgg tatttaccca cttttgaaca aaccaatcat gattacaggt
    20401 gcttcttacg gtacgcttgg ttcatctcgt gcccaattgc aacttcgtca aatcttgaat
    20461 gctcctgaaa tcaaggcaaa tgttcttcca gatgaattct tgctctcaca ctctcttcaa
    20521 gcatttaacc caagtggcga cttggttgac cttgatgtta tcaagaaatt ggatgccatc
    20581 tttgatgact tccgtatctt cgtgaagatt actgagaaat tgcgcaatgc gcaagaattg
    20641 cttcgcaaag atgctgaaga ctttgactgg gaaaatttgt aagataggag accgaaagaa
    20701 tgaaatttgt tggacttgtt ggatcaaact acgatcaatc atataaccgc aaactcttgg
    20761 aatttatccg tcgcaatttc aaattcaaat ttgaattaga agtacttgaa atcgacgaag
    20821 ttccaatgtt taaccaagat gaaaaatggg acgaaagctt ccaattgcgt ttcttgtata
    20881 acaagattac acgtgctgat ggtgtcatta tcgccactcc tgagcacaac cacactatct
    20941 cagcttcact caaatctgta cttgaatggc tttcatacga agttcatcca tttgaaaaca
    21001 agcctgttat gattgtgggt gcatcatact atgaccaagg aacatcacgt gctcaagttc
    21061 accttcgtaa aatccttgat gctccaggtg ttaatgccta cacgcttcca ggtaacgaat
    21121 tccttcttgg taaagctaag gaagcttttg ataacaacgg aaatatcacc aacgaaggca
    21181 ctgttaaatt ccttgaaact tgcttagata actttgttaa atacgtagga gtcgtttcga
    21241 aattgaaaaa accaaaacca atcgaatcag aagacttgga ttgtggaaaa ccaatcgcta
    21301 caaccatcac agaagttgac cctgacgatc cagaatgggt agaaaaagtt gcagcaatca
    21361 ctggtgctgt ttctggtgat acctatgtca aattggacca cggtatccta acagttaacc
    21421 aaattgatat gttcttgaaa gctatgccat ttgaattgac atacgctgac gacaacaacc
    21481 aattcctcta ctacaacaac gctcaccaag atccagacac tatgttcgct aaacgtgtac
    21541 cacctcaatc aggtagccgt atgtcgactg ttcatggttc tcttccacca gcacgtatga
    21601 agaacgtaga gtgggttatc ggaacacttc gcaacggaaa ccaagaatac gtccgtacga
    21661 tcgttccagg ttctcctgca ggtgttatca acactcacaa ctaccaagca atgtactatc
    21721 ctgatggatc atacgctggt atcaatgaaa tcgtctttaa cttccaacca tggcttgact
    21781 ggtacctaaa agagactggt caacgtttgg tgggtggtag cggaccattt gctcctgctg
    21841 ccggaggtca tggagacgcc gatgctactt ctggcgcttc tgattcaggg gatgctggag
    21901 gccacggtgg tgacgcagac gctacagccg gtgcaagtta ctaatgatag tttttaggaa
    21961 ccattatggt tcctttttta gcgaaaaaag actagcaaac acaaactgct agtctctttg
    22021 ttaaaagaaa gagtatatat tatgaatttg ggtcatcaag actacggcca tgtaatcctt
    22081 tttcacgttg tacttggcgt agtttttctg gtgtaacatc gtttccttct tcgtccacaa
    22141 ttttgattcc ttcaatgtgg tgacgaacag cgcggcgata accttcgatg tactcctcac
    22201 gtagtttggc ttgttccact ttttcttctg gtgttaagcc ttctgttttt ttctttttag
    22261 caagctcatt gatacgagca atttttttcg gatccatttc ttctcctttg taataagata
    22321 aagtccgttt atcaaatttt atttagtgtt aatttggtta aaacaagcaa acttagctgc
    22381 tttcttggtt agttgtgaca agattgccaa acgattttga cggacagcct gatcttcagc
    22441 cattaccata gtattttcaa agaaagcatc aatgactggg ctaagcgcaa agagttgttt
    22501 caattgctga cttgcaggtc ctgataaaac gagtgtttct actgcttctg ccaaagcttt
    22561 ttcttggtca ttctcaaata gttctgaatc aactgtagca accccttctg ccttctcagc
    22621 caggttaaag gcacgagaaa gtgattcaac agatggttta aaatcttctt ccttgcttac
    22681 ttctacgaga gcacttgctg cttccaacat atctgccaca acaaagtttg aacctgcaag
    22741 aactgcttcc ttgatatctt ttggagtaga gcccatcatc ttatcaacac gagccttgat
    22801 aaagtccata acctctgctt tattttcata agtcaaactg tcaaatttca atgcataaag
    22861 gctatcaatc agctcatcca tagcaatgtg ccaaccaaag gcatccaaga tacgaaccac
    22921 accttgagtt gcacgacgaa gggcataagg gtcattagaa cctgatggaa tcaatcctac
    22981 tgagaagaaa ctcaaaatcg tatccaattt gtctgcaatg gctagaactg cgccgacctt
    23041 gctctctgga agttctcctt cagctgatgt aggcatgtag tgttcacgaa tagcagctgc
    23101 caccgctgga gtttcaccag caagaagggt gtatttttca cccataattc cttggagttc
    23161 gtcaaattca ccaaccatac ctgtcaacaa gtcaaacttg taaatggctg ctgcacgagc
    23221 aaggtcaact gtttcatcca ctgacaaacc agctttttct gccaaaagta cagtgatttg
    23281 acccgtacga atcatgtgtt cacgaaggga accaatcttc tcatggaagg tgacattgtt
    23341 taatttttca acaagatctg aaatcaccaa tttttggtct tcacgccaga agaattctcc
    23401 gtcttccaag cgggctacca agactttttc atttcctttg atgacatttt tcaaacgctc
    23461 tgcgtttccg ttacgaacag aaatgaagtt tggcaagagt tttccatctt gatcacgaac
    23521 aacaaagtaa cgctggtgtt ccttcataga agtcaccaag acttcttctg gaacttcaag
    23581 gtatttagca tcaaaacttc ccatgaaggc agttgggtat tcaaccaaat tcaagacttc
    23641 attcagcaaa tccgcatcaa tttcgatacg tacaccatgt tttgcctcaa tttccttgat
    23701 ttggtcaaca atcatttgct cacgttcaca tggatctgcg attacaaact gcttacgaag
    23761 gtcttcttca tagctcaatg ctgactgaat tttggtttct ttccccaaga aacgatggcc
    23821 acggctcaca cgacttccct tgatatcaag gaaatccaag tcaaactctt gctcatccaa
    23881 gagaacagtt aaagtgtgga caggacgaat gtattcaaag ctatttccag cccagtgcat
    23941 gctgacaggg aaagtcaatg acttcaagac atctacaaca ccaggaacaa tggcttcaac
    24001 tgattggcca acttcttcct tagtgacata gacatattct tcacccttaa tttcacggaa
    24061 ttcgatatct tcaacagtca aacctttccc acggacaaat ccttgagctg ctttggtgaa
    24121 gtttccatca ctatccaagg caattttctt tgctggtccc ttgaaatctt ctgtcaaatc
    24181 agactgtttg tctgataaac cagtcacacg aacagccaaa cgacgtggtg ttgagaaggt
    24241 ttgaatggct tcaaaagaca ggcggttttc cttgaggaag gctgccattt tttcgcctag
    24301 ttgtttttca cttggtgtga caacataggc tggtaattct tcaagaccga gttctactaa
    24361 taagtttttt gtcatgtttt ttctccgaaa agtatctttt tattttccag tttgccttat
    24421 gtgattggca cgcaagcaac caacttcgtt gtttcattgc taaaattgga gccaaaagtc
    24481 tccaattttg cctagtatcc ttagtttcac taaggatacc ttcatcactg cggcaactgg
    24541 ctcagggctc actctgttcg cccattttcg taatttgtca ctctctttat tctgcgtctt
    24601 ctgctaggag tttagctctt gtttcttcat ccaaaagtgg gtagcctagg cgtttgcgtt
    24661 ctgcgacaaa ggttttggct acgacacggg ccaagttacg gatacgagcg atatagcctg
    24721 cacgctctgt tacagatacg gcaccacgcg cgtcaagcag attaaaggta tgtgaacatt
    24781 tgagaacata gtcataggca gggtgtacca agccttcttc taatgcacga ccagcttctt
    24841 tttcaaactt atcaaagttt tcaagcaaca tttcttggtc cgaaatttca aatgaatatt
    24901 ttgagtgctc atactcaggc tggataaaga tttctccgta ttttacacca tcagcccact
    24961 cgatatcata gacagagtct acttcttgaa tgtaagaagc caagcgctcc aaaccatagg
    25021 taacttccgc agtcacaggg ccagttgcca atccaccgac ttgttggaaa taagtgaact
    25081 gagtgatttc cattccgtca agccaaactt cccaaccaag accagctgaa ccagttgatg
    25141 ggttttccca gttgtcctca acaaaacgaa tatcgtgctc caaaggattg attcccaatt
    25201 tttccaaaga ctcaaggtaa agttcttgga tatttgatgg agaaggcttc atgaccacct
    25261 ggaattggtg gtgttggtag agacggttag ggttttcccc ataacgaccg tcagcaggac
    25321 gacgtgatgg ctctacataa gctgcattcc atggctcagg tccgatagca cgaagaaaag
    25381 tgtaaggact cattgttccc gcaccttttt cattatcata agcctgcata agcatacaac
    25441 cttggtcatt ccaaaattgt tgcaaagtaa ggatgatttc ctggaaagtc aatttcttag
    25501 acattgttta ctccttttta tataaattac ttgcgacatg aggctgcctc gtcgatcata
    25561 cgaggcaaga cgagttagta ctgcgtctag ctcaggcact ctagtgctga gcgtggggca
    25621 gtccgactgt aaggaggttt ctgccactga tgcagtgaaa tgttaatttc tcagacattg
    25681 aatactcctt aataaaaaat aatttcttgc gacacgagtc tgcctcgtcg attatacgag
    25741 gcaagacgag ttagtactgc gtctagctca gcaccctagt gctgagcgtg gagcagtccg
    25801 actgtaagga ggtttctgcc actgacgcag tgaaatgtca atttcttaga cattgtttac
    25861 tcctttagtt tttatatttc tttttcaatt aatttctgct gaacaaacca atctaacaag
    25921 ggaaaagttt tttctgtatt tgcccataaa tgataagaat ctaagaccgc ttgtacacta
    25981 cctaaatttt ctaccaactt atctactgtc aaaaagctgc gccagtattc ataaaaaata
    26041 cttgcatagt tcttatcata agtcgaagaa ccaaaatcat tcaatgaatg ccaaccatac
    26101 ttcttctgaa aaagttctac gagagattga ttacaaattt tttccgcttg aaattcctct
    26161 tctgtcaaga aatacttgcg actaatatat tcaaccatcc cctcttcgaa ccagatataa
    26221 gagtcataac catcaaaatc atctaaaaaa tgctccgacc aatgagctaa ctcatgtcct
    26281 acaatctgta agaggaaatt ttcagataaa gaatgatagt gactttctat tgcttgagtt
    26341 tgctgagaac actcgtagtc catcaattga tacaaataca actctttcca aacagctaaa
    26401 tcaggcgcca taaccattcg tctattattt gtataggctg gaacagcgct ttccctaata
    26461 atctgtgtag cagcattaaa atctgaccaa ataacggctt gcggtaaatc acagactgca
    26521 agttcattct ttaaaaaaga ttgataatct ttcaactttt cagtatttct tactacaaaa
    26581 tcacgaaatg tagctagttg actatcgtct tttacaagat aaaggttgtc cacggctctc
    26641 ctttctttca cacaatagac tgaataagca aaagaaccgc gtccgacaat cctaggttga
    26701 tttaacctag gggcgtcaga aacgcggttc caccctaatt tattacttca ttgtttttga
    26761 aaatactaca gaaagcgcca gctcattatt ttgccctact tggctcccac tatcccaagc
    26821 tcgcttgaag aacgccataa gactttcttt cctgctgact attatatcaa aaattagaat
    26881 aatgtacaat tctttttatg attttctaga aatccacatc atcaactcgt ggagcacccg
    26941 attgaacagc aatcgttttt aaggtttctc tctcctcatg actcagttca attccaaagc
    27001 aatcaagatt agcttgaata cgagaggttg tgacagattt tggaagtggt aaaaatcctt
    27061 ctgccaagct ccaggccaag gctatctgag caatcgattt tccgtgattt gctgcgattt
    27121 cttgcacttg cttgctatca aatagttctc cctgaccaaa aggcccccaa gcttccaata
    27181 aaattccctt ttcacgacag taagctacga cttgatcttg atacacacct ggcgccaagc
    27241 gaacttgatt gaccgcagga acgatagttg cagtttcaag caaggcatcc aaatgatggg
    27301 gaagaaaatt gctaacgccg atagcacgga ttttcccttc ttgatagagg tcttccatcg
    27361 ctctccaaac ttccgcattg cgagttttcc atgcgtcatt ttctctgagc ggttttgggt
    27421 tcggccaatg aatcaaatac aaatccaaat aatccaagcc cagtttttct atagattttt
    27481 ccaaagcttg acgagtttgc tcataggttt gctgactatt ccaaagcttg gtagttacga
    27541 acatttcttc acgtggaact ccgctatctt tgattgcttg accaacactt tcttcattct
    27601 gataaatcgc cgccgtatca atatgacgat aaccagcctt caaggcttct aacactgcac
    27661 gataggcttc ttctccatcc ttagccttaa aagttccaaa tcccaatact ggaatttcta
    27721 ctccattatt taattgatag gtattcatat gcttctcctt ctattttatt catcaattat
    27781 agcataaaac attttttaag tagtactatc ttctgtaaaa aataagtctg tcaaatatct
    27841 aacagaccta ttttttcttg cttattcatc acgactatag tacagctcat gagcttttag
    27901 gcgagtattg agcatctctg gtatggtcac aaaggtataa ccttgatttt tcaaatactc
    27961 aatgaccctt ggcaaggcat tgactgtcgg actgtgaata tcatgcatca aaacgataga
    28021 gccgttagct acttgatgct gaatttctgt caaaatagat gcttcatttt tactcttcca
    28081 gtccagacta tccacatccc acatgataaa gctcaaatcc aagctattgc gaatatcatc
    28141 tgtaatagca ccataaggtg gacgcatgag tttagaacta gaacccagca ctttagttag
    28201 cacatcctca gtatcagtaa tctgcttttt agcttcatca agagagagtt gcgagagaat
    28261 cggatggctc caactatggt ttccaacaac atgaccttca gattttatcc tcttcaccaa
    28321 gtcctcattc ccagaaacat ttttcccaag cacaaagaaa gtcgctttaa tatcatattt
    28381 agctagggtc tctaatacct gcggggtcgt tgctggattt ggaccatcat caaaggttag
    28441 agcgacaact ttttgatatt tcttatcaaa gtaagattgg tacaaggccg catctttttc
    28501 gagtaagtac gaagattgga taacatcaaa gaaagcagat actggcaagg ctatctcttc
    28561 taaattttca accacaggac ttggataaag gataatctga ctatccttgt aatcaaaatt
    28621 ccatgcagac aagtcttggt cagagaagtt ttttacaatc tgctcactct ggtcttgctc
    28681 tattttttta tcctctatga aggaggtcaa ctcttttatc agctgttcct tagccttact
    28741 aacatctgaa aacagttggt caagtgtaaa aggttgccca tcttctgtta agtgaacctt
    28801 tcctagactg gtcttttcag tctcttcaac cttaaaagca actaaatcat agatttgttt
    28861 ggtcacatta cgattaacga ctccctttaa acctgactct tcttgctctg tatagtagaa
    28921 aacaagattg tccttacttt ctagcttgtc cttaacatct tgatttatca actccctaac
    28981 agaggaaatc actttctccc cttggagagg ataataggca atcacttcgg cttgcccctg
    29041 acgaaaatgc tccttctgat ttccctcact caattgatca tctttctctt ttttgagcga
    29101 ttcaatcttt tgctcaaaac ttttttgctg gtagatctta aaagcaataa atccgcctaa
    29161 taggcaaata gaaattgcta aaataccaat caaagccaat aatacatgtc tcgttttccc
    29221 gtgtctgcca cgtcctagtc tacttttatt catatttata tcataacaaa tttgagcaat
    29281 aatttcaatg atacaatttg gcaatccaca attcctctag caagccaaag catcttacat
    29341 caactccaac atccgtatct gtagagatta tgtagttttc tatctatgga atttctagta
    29401 gattgaagct agaatagtag acctatactt ctaaaacatt gttagaaatc gatttgattg
    29461 tcctgatcga tttgtcctgt tcttatttca ttttactata aaactatgag aagctaggtc
    29521 atctgagaag taattactat cgacaattgc gatagcgtat actggtgcaa tttgtttgta
    29581 gctctggtgg gtatcacctt cacgttggcg aattttttct aggttttgat taacctgact
    29641 gcacagataa gcccataggc gattgatgaa aaaattctga tgatgaacct gaatttcgat
    29701 gataacttgg gttccattat ctaactccgc caagacatct atactagtat agaaatcctg
    29761 cgctgagtag ggcatggaag gcaagacgtg aatgttactt ccctccaaaa tcgtcacatt
    29821 ttttgctggc aagtccagca tatcgcggat aaattgacaa agcattagtt gggctgatac
    29881 ccggatgtct gagaatcctc cttttcctcc tttttctcct tttcctcctt ctattatagc
    29941 acatttttaa atctaggttt gctagattct atgcttctat ctatttattc ggaaaagaaa
    30001 gcttttcttc agaagaaagc taatagctta tttgaagttt tctcctctct gttggatagt
    30061 cccgtctatc tatgttataa tgaaagaagg atttaaaatc ggaaaaggag tatttatgct
    30121 aaaattaggt gtcatcggaa ctggcgctat cagccatcat ttcatagaag cagcccatac
    30181 cagtggagaa taccaactgg tcgcaatcta ttctagaaaa ctagaaactg cagcaacctt
    30241 tgcttctcgc tatcagaata tccaactatt cgatcaatta gaagtcttct tcaaatcttc
    30301 ttttgattta gtctatatcg ccagtccaaa ctccttacat tttgctcagg caaaagctgc
    30361 cttgtctgct ggtaaacatg ttattcttga aaagccagct gtcactcaac cacaagaatg
    30421 gtttgatttg attcaaacag ctgaaaaaaa taactgtttt atctttgaag cagctcgtaa
    30481 ttaccacgag aaagccttta ctactatcaa aaacttttta gcagataagc aagtgttagg
    30541 agcagatttc aactatgcca aatactcttc caagatgcct gacttgttga ctggacaaac
    30601 accaaatgtc ttttcagacc gttttgctgg tggagccctc atggatttgg ggatttatcc
    30661 cctctatgct gctgttcgtc tttttgaaaa agctaatgac gctacttacc atgctcaaca
    30721 gcttgacaat agcattgacc taaatggaga tggtatcctc ttctacccag actatcaagt
    30781 tcacatcaag gctggaaaaa acatcacttc caatcttcct tgcgagattt atacaacaga
    30841 tggaaccttg actctcaaca cgattgagca tattcgctca gctatttttg ccgaccacca
    30901 aggaaatcaa gtccagcttc ctatccaaca ggctcctcat acgatgactg aggaagtcgc
    30961 tgcatttgca cacatgatcc agcaaccaga tctgaatctc taccaaactt ggctgtatga
    31021 tgcaggctct gttcatgagc tactatatac catgcgccag actgctggca ttagatttga
    31081 ggcagaaaaa tgaaaaccaa actaccgact gaatggcaag aactgagtga ccaactcggt
    31141 ttccaagaat tcacccccat tcaaactcaa ctatttgagc tccttcttgc tggagaaaac
    31201 ctcctaggag tgagccaaac cggaactggt aagaccctag cgtatctcct accaagtctt
    31261 ctcagactac aaaagaaaaa agcccaacaa ctcttgattc tagcaccaaa cacggaactt
    31321 gctggacaga tttttgatgt atgtaaaacg tgggcagaag ctatcggatt gactgctcaa
    31381 ctcttccttt caggttcaag tcagaaacga caaattgaac gtcttaaaaa ggggccagaa
    31441 attctgattg gaactcctgg ccgtatcttt gaactcatta aacttaaaaa aatcaagatg
    31501 atgaatgtgg aaaccatcat cctggatgaa tttgaccaat tactagatga ttctcagatt
    31561 cactttgtag agaaaatcac tcactacgca cctcgtgacc accaactggt ctacatgagt
    31621 gccacgacca agtttgacca agaaaagatt gtgccgaata cacgcactat tgatctctct
    31681 gatcaaaaat tggacaatat ccagcatttc tacatgcagg tagaccaacg tcatcgagtg
    31741 gatatgctac gaaaactggc tcatgtagag gatttccgtg gtctagtctt cttcaatagc
    31801 ctgtcagacc ttgggaatgc cgaggaaaaa ctacagtatc gtgatatatt ggctgtttcc
    31861 ctcgctagtg atgttaatgt taaatttaga aaaatcatct tagaaaagtt taaagataac
    31921 caactaaccc tgcttcttgc aactgacctt ttggctcgtg ggattgatat cgatagccta
    31981 gaatgtgtcg taaactttga tattcctaga gatagcgaaa cctacacaca ccgtgctggc
    32041 cgtactggtc gtatgggcaa ggaaggttat gttatcactc tcgtcactca tccagaagaa
    32101 atcaaaaaac ttaaaaagtt tgcaagtatc cgagaaattg tcctaaaaaa ccaagaactc
    32161 tatatcaaat aaagccccat tgctctatac acatccagtg tatggagctt ttttacaagc
    32221 aattcaattt tatactcatc tgttttcaaa aagcattcta gtccatctcc gattaacgat
    32281 gggctttatc acctccttct ccagtccttg tatgatatct tgaagttgat tcatgacatc
    32341 ttccaaagtt tgaaaggctt tattcttaaa tccacgttta cgaatctctt tcaacacttg
    32401 ttcaatgggg ttcatctctg gtgtgtatgg aggaataaag gtaaaaccaa tattagtcgg
    32461 aatctttaag gtacttgatt tatgccatat agcattgtcc ataacgagta aaaggataag
    32521 cttgtgaaag ctcttctaaa aaggcgttca tccactcagt attacatcta ccagctatta
    32581 agaaaaatga ttcgcctgta tgggcatcaa cagctccata acaatagcga aattctcgta
    32641 tatagtgact atggacatgt ggacctactc ctattggaga ccaacaagat cccagtttac
    32701 tgattctacc gaaaccagcc tcatcttggt acatcaagcg aaccttacga aaacgtctac
    32761 tatatttaaa tcgctttctt gccttcttga attgagattt tatttttaga cgcgacaatg
    32821 gtttgagcgt ctgttttcct aggatgttct ggacgtggca taatatttcg ccagccatgg
    32881 cgcttcaaca gttgatagaa ggcatcacgt gtgtaggaac gacctaactc ctttttataa
    32941 gcctgaaata aggcatcaat tgtaacaaat tctcctgcct ctgtagcctt caaatgacgg
    33001 gcaagaaagg ctttctcttc ctcaactgtc atatatgcat ggttacgacc accacgtgtt
    33061 tcttgaagga gagagtcgag tccgaactcc tcatattttt tacattttgc taaatcgttg
    33121 tttgattaca gtctaaaagc tctataatct ctttataaga tttgcccatc agacgaaata
    33181 gaacgatttg aaggcgttta tgatatttag ctgtacgaga gtcttttaaa agtgttttga
    33241 tggtttggat ttcttcttta gttgatttca tattactatt gtataatgct ttttgatttg
    33301 agtctagtat tatactcttc gaaaatctct tcaaaccgcg tcagcttcgc cttgtcgtat
    33361 agatgttact gacttcgtca gttctatcta caacctaaaa acagtgtttt gagcagtctg
    33421 cagctaactt tctataacaa aatgaaataa gaacaagaca aatcaatcaa gacaatcaaa
    33481 tcgatttcta acaatgtttt agaagtagat gtgtactatt ctagtttcaa tatattatag
    33541 tttgctcttt gattttcatt gagtattagt tcaatatcta aaaaaagaac cttgccaagc
    33601 aagattcttt tagtgtctga cttaaataat tgttcttctg ggaactaaat cgaattaagc
    33661 ttcgatttct gtaaccatac ctgaaccaac agtacgtcca ccctcacgga tagagaatgt
    33721 agtaccttgt tctacggcga ttgggtgaat caactcaacg tcgattgtca cgttatcacc
    33781 aggcattacc atttcagtac ctgctggaag ttcgattgaa cctgtaacgt cagtagtacg
    33841 gaagtagaat tgtggacggt agttgttgaa gaatggagtg tgacgtccac cttcttcttt
    33901 agtaaggatg tagacttcac ctttgaattt agtgtgtggg ttgattgaac ctggtttagc
    33961 gataacttgt ccacgttcga tttcatcacg ttgaacacca cgaagaagga cacctacgtt
    34021 atctccagca agaccttcgt caagttgttt acggaacatt tcaacaccag taacaactgc
    34081 tttttgagtt tcttctttga taccaacgat ttcgatttcg tcgttgactt taacgatacc
    34141 acggtcgata cgtcctgaag caactgtacc acgtccagtg attgagaata cgtcctcgac
    34201 tggaagaagc aatggtttgt cagtgtcacg ttctggttct ggaatatact catcaactgt
    34261 gttcatcaat tccataacga tgtcttcgta tttagagtca ccttcaagag ctttaagtgc
    34321 tgaaccttgg ataactggaa gatcgtcacc tgggaagtcg tattctgaca ataggtcacg
    34381 gatttccatt tcaaccaatt caagcaattc ttcgtcgtca accaagtcaa ctttgttcat
    34441 gaagacgata aggtgtttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg
    34501 tggcattggt ccgtcagttg aagctactac aaggatagct ccgtccattt gagcagcacc
    34561 agtgatcatg tttttaacgt agtccgcatg tcctggagcg tcgatgtgag cgtagtgacg
    34621 tttttcagtt tcgtactcaa cgtgcgcagt gttgatagtg ataccgcgtt cgcgttcttc
    34681 tggagcagca tcgatagacg catagtcttt aggttggtta actgatgaag gcaagcgacg
    34741 tgccaaaaca gttgtgatag ctgcagttag ggtagtttta ccgtggtcaa cgtgtccgat
    34801 agtaccaatg ttaacgtgtg gtttactacg atcgtatttt tcttttgcca tttgagtaaa
    34861 agcctccaat aaaatatatt ttatagatag acagtaggca atacagtcta actttcctta
    34921 ctattttatc aaatttcagc taaattgcaa gtgttttaca acgtttttgt gaattattct
    34981 tggtaaaaat ttaactaatt aatagaaagt actaaataga cttatccttc aaggagtttt
    35041 cagcattatc catccactca cttgctgaaa atgtaaacag tctctggttt atatagtaaa
    35101 atgaaacaag aatagggcaa atcgatcagg acaatcaaat cgatttctaa caatgtttta
    35161 gaagttgaag tgtactattc tagtttcaat ctactataca acctcaaaac tgtgttttga
    35221 acaacctgcg gctagcttct tagtttgccc tttgattttc attgagtata aaattgcaga
    35281 taaaacgata acaatcatag gactcagcag agtcaatgta ggtcgaagaa tagcccccct
    35341 aatcgcttat tttatagcaa aatgaaatag aaactgaaca ttttgttgag gaaggtaaat
    35401 caattcctca caatgtttga gaaagaaggg aggactattc caacttcaac ccactataaa
    35461 gcagacttac aagataggga acccatctcc gataatattc cgataatata tagtagaatg
    35521 aaaactgcac aatttgattg gagaattcaa accaatttct aacaatgttt tagaaacaag
    35581 agtctattat ttcaactgca acctactata gcccattgaa gctggaatag cccactgaga
    35641 cttctaaacc actgctggag aggagtttgt ttagagtttc tttcatttcc ctaaaaaatc
    35701 aaaaagagag aaccagtctg atcctctctt acttatagat ggtgctcatt caaatgttaa
    35761 aggagctatt tcttagagat aaaggaattt gaatacagct actgccgcaa ttgctgctgc
    35821 gataggtgct actactggta cccaagaata ccaccatttt gaatcgcctt tatgctcacc
    35881 aagaactgat tttggaagga aagcatgaag gagacgtggt cccaagtcac gggctgggtt
    35941 caaggcaggt cctgtaggtc ctccaagtga tgttaccaaa gccataacga ggaatccaag
    36001 tgccaagtga gccacagaaa gtcctgaagc agtgtgtgga gccacctgtg ctttaatagc
    36061 caagtcagaa aaatcaactg tttgtcctgc ttctattgcc ttttgtttca tgaattgaag
    36121 cacttcagca ccaaagaagt ttttagtcaa accaagagct gcaaagaaca aaacaaatga
    36181 accaacaaac tcattaatca aaccattgac agttgctgca tagcgacttt cttttgtacc
    36241 atggtcaata cttgaaatag ttgagaaagt tcccaagatg ttatttggtt tttcagtttt
    36301 caagtagaat ggacggtatg ttgccacaac taaggcttgg ccaaagatag cccccaagac
    36361 ttgcgcgata atgtaaggta ccacttgtgc ccaagggaaa agaccgctaa ctgcaagccc
    36421 tagagtgaaa gcagggttga tgtgattccc agatacgtta ccaaacatca aggctgggat
    36481 cataaccccc ataccataac caacagcgat gacgatccag ccactttggt gacctttcgt
    36541 acctttaagt tcaacattgg caactgcacc attcccaaga atgatcaaaa tggcagttcc
    36601 caaaaattca gtggcatact tcagtgccca tgtgaaatcc atttgctaga ttctccttaa
    36661 aattttttag atattcctta ttttatcaat ttttacccta tttagcaact gatttctgga
    36721 aatattttta aaaaaatagg attcatagtt tcccagttca acgcacttgt aagcgttttt
    36781 attcttcacg aaagacctca ttctcaaaac caggaaaaag cccacatcta tgagcttttc
    36841 ctggttccta gattctaaaa tctattattt ttcatcttct tttttcttga agaatcctaa
    36901 tcctagacta gctaacaagg tcatgatacc agcactagcc aaggtagcat tagcttctgt
    36961 acctgtgttt ggcaattcct ctctcttacc tgtctcataa gtcggaactt ctgggtctgg
    37021 attcactgga gtttcagttt ttggagtacc tggttctgga gttggtttat ctggtgttga
    37081 taaacggtca taccttaccg ttatttcttt atcactagag tctgacgtaa cttcttgtga
    37141 ttcaactgtt ggaatatctg gatctttgta cttgtcaatc ttaccagata taacctcgtc
    37201 ccagtttcct gttgtccatt caccgtaggt tacaactccc gtgaccttgt tctcagtttt
    37261 tgtacggctt aaggttacag gttgaacaac atcttctttt acattttggt tcgtaacttt
    37321 atcaacgtaa tgaatgatac gcgttatagt cttcgtctca gtagaggtta ctgttttggg
    37381 aaccactgtt tcctcaacat tctcacggta gtaatagtca actgttgcac cgtcttctgg
    37441 tacgcatttg caggagttgc taccaaggtg tatgttgttt tccttgtgat aactcggtct
    37501 tctttgtcct cagttgttgt tttcccttca atagtttttg attctgtggt atactcagaa
    37561 cctatcgcta aatcagcttt tataacagac tctgccaact tctcttggct accttcttta
    37621 tagtaattgg ctgttactgt agcagtggtt ggcgcttcgc tttctctata aactaaggtc
    37681 actgttctac cttcgcttac aatattccca gttaaacttg cagaatttgt atctgcttct
    37741 ttaaaagtat aatattttcc gtcagtagta gtcatgctac tgagtttttt atctgtgaca
    37801 ttgtagctgg taccaatcag ttgtttttta ttggtaatgt aggttccgtc actttctttt
    37861 tctccaattc cagtatcatt tttcaatgat agcaaacgcc cttgttcatc aacatagcga
    37921 actttcacat tttctgagat tagttctgcc aattctgagg tttttttctt tttctcttct
    37981 tcgggaatat ttagttttgg aatgattttt tcaataacgg ttcgtgatgg ttccacagta
    38041 tcttggatga ctgaaaagtc agctagaatt gggagattat actgaacacg gtgactttga
    38101 gtgtttactc ctactctttc attattctct gaaaatactt gtacggtata agaaacaaca
    38161 tcttttccta atagaacatc cccagtagag aaatagccgc cttttcctag tttgctatct
    38221 ccagagccca cttctttcct aatcttatca gatagttttt taccagtcag tacattcgtt
    38281 cgcacaatcc ctttgtctac ccctacaaaa tgggagaact ttttgaactc ttcagaacca
    38341 gatctagccc aaccattatt aagggcattt gcttttgtat ttgtattctc tcttaaaggt
    38401 ttggcgatta gaattatatt catcggcact tagagttgct gctatatctg actcttgaat
    38461 accaacttcc ttactaccat ttctagcggc agtatatgtg tatttatctg tttctacttc
    38521 tagctgatta tccttaacat gataggtaat tttctcctgg tataagagtc ttcagtagtt
    38581 tatatgctct gtcatcatct ttagctttag aagcagctga gtttagccaa gttggggtat
    38641 taggagtatc tttatcagcc tgtttcaaga cattattcaa gtcatttgct agcctattgg
    38701 ttgtcctcac tgtgaaagtt ttcttccagt ctgaaccact tttattagac ttagatatgc
    38761 tcatgaaatc ctggtcaaca ttcaacacaa tatcgccttg ttttttagca tcttccgttg
    38821 cttctgcttc aaattgatca tggagttttt gttgctctgg tgtatagttt ttttatttac
    38881 acaatttaat gtactatttt ttattttagt attaagaact ccattaatac gatttttaaa
    38941 ctctgcttca aaaaatccct taatttgttg gtgcgcaagt tcaacattca aacctttttt
    39001 atacaagtct tcattctgaa cgatttcggc tacacggtga atggtttgat cgtataccgt
    39061 cttctcttaa ccagcagtat ccttagtttt aatgactact cgataggttc ctttagaacc
    39121 gttatagtca tctagtttta aaaaagcatt ccaaacattc aaaaatagtt ggaacttccc
    39181 ttaataaatc cgtcactttc tttttcaaga tagcccaagc ttgctcaata ggattcaaat
    39241 ccggtgaata aggtggtaga ggtaagaaaa agtgtttatc ttggatgcag agttcatcca
    39301 aaatgttctt gggatgaaaa ctagcattgc ccatgacaat aacatgaggt gtcttcaaag
    39361 caggtaggag ttgcgttttg aaccactcca caaagaaatc gcttgtcatg cttttcttgt
    39421 aaatcatggg agctataaac tctccgtcta cttgtcctgc aacaattgaa gttcgctcaa
    39481 aacgacgtcc gctaatcttt tcatagactt tctcccctct aggagcccgt gcataaggac
    39541 gatagaggta gcggtcgatt cctgtttcat caatatatac gattggtaaa tcttttaggt
    39601 tatccaaaat atcaagaaac tcagcgactt tctctggctc ttgttcctta aagctcgtca
    39661 tcttttttta aagtgacctt aatatacttt aaagctgccc atacggaggg cagagcacaa
    39721 tcaaaatgtg ccgcaatttc ccgtaaaaaa gcatctgaat gagcctctac aaaggctttc
    39781 aattcctcta aaggaatctt tcggtttttg acgactcgct ttttcctctc tatgtgtcct
    39841 tgttcacatc tttcttttcc cacgtgaaga gagttctgac gccaacacca aaaaacttgg
    39901 ctgcctcgac atggctgtgc ccctctttga tggaatctaa tgctcgctgt ttaaaatcag
    39961 tactatatgc catagcttta ttataatatg cttgtttaaa actaagcaac tatatcaatg
    40021 ttttgttatt agaagactta ctttttttac tgaaatcgaa tttttcctaa cctcaacatc
    40081 atataacccc aaaattcaat ctgacctggt ttgaagagat gttcgaagca gataaggttt
    40141 tactaaaact aaaaaaaatg atataatcaa actgattaaa tgttttaaaa ataaaggaga
    40201 atttgaatgt cttaccaaga aaattaccag aaatgggttg attttgtgga gcttcctgac
    40261 taccttcgtc aagatttgga aaatatggac gaaaaaacta aggaagatgc cttctataca
    40321 aatcttgaat ttggtactgc aggtatgcgt ggcttggttg gtgctggtac aaaccgtatc
    40381 aacatctacg ttgttcgcca agctactgaa ggattggctc gtttgattga gtcaaaaggt
    40441 ggaaacgaga aagaacgcgg tgtagcaatt gcctacgata gccgtcactt ctcacctgag
    40501 tttgcctttg aatctgcggc agttcttgct aaacacggca tcaaatctta cgtatttgaa
    40561 agccttcgtc caactccaga actatcattt gcagttcgtc atctcaactg tttcgcaggt
    40621 atcatggtca cagccagcca caaccctgct ccatttaacg gttacaaggt ttacggtgaa
    40681 gacggtggac aaatgcctcc acacgatgcg gacgctttga ctacttatat ccgtgcaatc
    40741 gaaaacccat ttgcagttga agttgctgat gtggaaactg aaaaagcttc tggcttgatt
    40801 gaagttatcg gcgaagctgt tgacgtagaa taccttaaag aggttaagga cgtaaacatc
    40861 aacccagcct tgattgaaga atttggtaaa gacatgaaga ttgtctacac accacttcat
    40921 ggtactggtg aaatgttggc tcgtcgtgct cttgcccaag caggatttga ctctgttcaa
    40981 gttgttgaag cgcaagcaac tgctgaccca gacttctcaa ctgtaacatc tccaaaccca
    41041 gaaagccaag cagcctttgc ccttgctgaa gaacttggtc gtcaagttgg tgcagatgtt
    41101 cttgtcgcaa ctgacccaga cgctgaccgt gttggtgttg aagttcttca aaaagatggt
    41161 agctacctca acctttcagg taaccaaatc ggtgctatca tggctaaata catcttggaa
    41221 gctcacaaaa acgctggaac tcttcctgaa aataccgctc tctgcaaatc tatcgtttca
    41281 actgacttgg taacgaagat tgctgaaagc tacggcgcaa ctatgttcaa cgtcttgaca
    41341 ggtttcaaat ttatcgctga aaaaatccaa gaattcgaag aaaaacacaa ccacacttac
    41401 atgatgggat ttgaagaaag cttcggttac ttgattaaac catttgtacg tgataaagat
    41461 gccatccaag ccgttcttgt cgttgctgaa cttgctgcct actaccgttc tcgtggtttg
    41521 acacttgctg acggtatcga agaaatctat aaagaatatg gctactacgc agaaaaaaca
    41581 atctctgtta ctctttcagg tgtcgatggt gctgaacaaa tcaaagcgat tatggctaaa
    41641 ttccgcaaca atgctccaaa agaatggaac gcaacagcta tcactgtcgt agaagacttc
    41701 aaggcacaaa ctgctactgt tgctgacggt actgttacaa acttgacaac tcctccaagt
    41761 gatgtgttga aatacacact tgctgacggt tcatggattg ccgttcgccc ttcaggtaca
    41821 gaaccaaaaa tcaagttcta cattgcagtt gtaggggaaa ccaacgaaga atcacaagct
    41881 aagattgcta acatcgaagc agaaatcaat gcatttgtaa aataaagacc tataaaagat
    41941 gagaccaacc aacctcatct tttttcgtat caaatctaag caattttaga aactttatgg
    42001 catactagac ttatcaatga aagcgaggta atctcatgga acaattttta gataacatca
    42061 aagaccttga agtcactaca gttgtgcgtg cgcaagaagc tcttgataaa aaagaaactg
    42121 caaccttctt tatcggtcgc aaaacttgcc cttactgccg taaatttgca ggtacattgt
    42181 caggtgtcgt agctgaaacc aaagctcaca tttacttcat caatagtgaa gaaccaagcc
    42241 aactcaatga tttgcaagca ttccgctcac gttatggaat cccaactgta ccaggtttta
    42301 ttcatattac agatggacaa atcaacgtcc gttgcgactc ttcaatgtca gcacaagaaa
    42361 tcaaagattt cgcaggattg taaaaaatca gctaacaagt cttaaaatca caaaaacgca
    42421 taatgtaagg tgcaaaaacc ttgatattat gcgttttatt gttcctaaaa cagttacatc
    42481 agcatttcat tacagaacat tttaattttg gaagtcaaat caatttttaa caatgtttta
    42541 gaaatcacag tgggctattc catattcaat tatccagatt caatcgctat tatcgttttc
    42601 ctagattaca aaaaaactac gttttgctaa tcaaaacgca gtttcagcca ctattttatc
    42661 ttactgtcct tcttttactt ctttggttgc tacatcttct ccaaaccatt tttggctgat
    42721 ttcttggaac ttgccgtcct tgtaaagact agaaaaagct tcatttatct tcttaaccaa
    42781 gtttgtatct tccttacggg ctccaaccgc aaaagcttct gtttctagtc caactgtaaa
    42841 gacattataa tcgtttaaaa caccttctgc ttctaaataa tagtttgcat agacacggtc
    42901 aatcaataga ccatcaattc gatcgttttt caaatcaatc aaggcttcat taaaggtttg
    42961 gtattgattc gcttccttat tagcgacaat attcttcaaa atttctggat ttgcttcaaa
    43021 gtccgcataa ccagatgaac cagcttgagc tcctaatgtc tttccagtca tatcctttgc
    43081 agtcgtgata ccagatgatt tcttcgtaac caatacctgc tcattcttca tatatgagtt
    43141 actgaaagcc accttttcac ggcgttcgtc tgtagcggaa tagccattcc aaatcagatc
    43201 aatcgttcct tttgtcaatt cagcttcttt caaatcccaa tcaatcggtt gccaatttac
    43261 cgtgattccg tatttttcaa aaacagctgt agctaaatca atatcaaatc ctgcataaga
    43321 accatctttc tgagcaaatc ccattggaac aaaagtacta tcaaatccaa tagtaataga
    43381 cttgttagac tggtactttg accaattatc tccactagtt tcgctagaat ttttcccaca
    43441 agctactaag aacaaagcag tcatcagact gactaataca agcatccatt ttttcatcca
    43501 tttttcctcc tatttaggtt ctactttcaa taatacatct gcgatatttt cagcaaactg
    43561 caaatcatgg gtaaccacaa tctgggtcat cccaagttcc ctattttgca agattagctt
    43621 ctccacttcc aaacgtaatt ctggatccag ggcagaagtt ggttcatcgt agccaatgat
    43681 ttctgggtca atcatcatag cacgcgccaa agccacccgc tgcttttgcc caccagatag
    43741 tgagaaagga taggcctctg cgtgtcctcc tagtcctaac tgttccaaga gtccactcgc
    43801 cttcttctca gcctcttcct gcttcattcc catggtcttc acaggcgata aagtcaaatt
    43861 ttccagaact gataaatgag ggaacagttg aaaatcttgg aatacaaatc ccagtagatt
    43921 gcgcttctgc aattcatcca gctctaaagg ttgtccatta taaaagattt gccctgaatc
    43981 aatggtttca agacctgcaa gcatacgtaa aagagttgtc ttacctccac cagaaggtcc
    44041 aacgatagcc aggatttgct tttcaggaat acttagactg aaattagaca ggatttgttt
    44101 gtctccaaag actttattga tatttcgtaa ttctaacatg gcagcctcct atctataata
    44161 actatacttc ttctcaactt ttttggaaat aattgtcaca atcccaatca aaatcaaata
    44221 aatggctcct gccaagaaca taggaactag actagcatcg cggttagcag ctgttcgact
    44281 agccaagata aggtctgaaa ttccgagagc atagaccaaa gaagtatcct tgaccaaact
    44341 cataacttca ttaaagacac taggaagaac gatcttggtc acttggggca agataatata
    44401 gcgcactctg tcaaaagggc taaacttcaa gaccttggcg gcctcatact gtcctcttgg
    44461 aatagtgtca attcccccac ggaaaatttc tgcaaagtaa gctgcatagt tgagaacaaa
    44521 ggcaataata gctgcaggaa ggcggtctaa acgaatccca atacttggga gcacataata
    44581 gataaaaatc agttgcaaga gtaagggggt tcctcgcata acccagatgt aaatgttaat
    44641 cagataatgg aggggcttcc aatggacttg caaggcaaag gcaatcaaaa cgcccaaggg
    44701 aatcgaaaat agcaagacca gtgcaaagac ctgtacagtc gtgctcgcac cattcagtaa
    44761 actcggtaat atctcaaata aataagacat actgcacctc ctaaaagtaa ttgttcctat
    44821 tatagcatga ataaacaaga ttaccaagta tttttgtaaa aagattctac catatacaaa
    44881 taaaaaccgt agctatcaaa agagataaac tacagttcta tatgtttaaa cattcttaca
    44941 atctctcaaa cagttcttgc atttgcacat catctggaac cagttttaag taagtgtgag
    45001 catggacttt tgcttcttca aaatgtccca attcacgcaa gagatagata tagtgttcca
    45061 gaaattctgg attgtccttc aaatctcctg tcaactcttg ataatgctca taagcagtat
    45121 ccaaatcgtc catttcttga taagaacgag caatcatcca cttggtcaaa agattttctg
    45181 gctcctcact ctgcaagtct agaatatcct cataacgctc ctgctccaga taaatagtgg
    45241 ctaaacgaag caagatttct tctgtatcct cagcgtcttc ttttgcagta aggagataat
    45301 tttctgcacc actagcatca tgcaattcat aagaaaattg tgaagcagct agcaagaggc
    45361 gagtttcaaa gggatttttc tctaatcctt gcttagcgat acgcagggct tcttgaactt
    45421 gatgttcctt atgtaaagcc tgactgtacc catactcata gccttcaaag tcaggagaaa
    45481 tggtatcaag ctgcttaaag tagagggtgg ctttttgata ttcttcttga tcaaaataaa
    45541 gactggccaa ctcaaaagct gttaagtcat cgtattctaa ctccagggct ttttctaaaa
    45601 actcagtagc cgtttcaaat ttccctaact gagcataggc aaagccaatt cgttgatagg
    45661 tggaaatgcc cgtttgctca taaatcgagc gattatctaa ctgggcatag gcttgaatag
    45721 ccgcttggta attttccaac tcactatcca actctgccaa acccaatatc aagagagaat
    45781 cctctgagta ggtcaaggcc tccaataatt tctcacgtgc cacatctgtc aaaccttcca
    45841 gctggtaaag gtctaccttc aaaaccaaag acgagacata ccagtcactg tcagcttgga
    45901 tttcctcaag ataggtaaag gcttcttcta tttgaccatc ctcgctagca attgcagcta
    45961 gattaagatg aacctctgga aaatcctcta caattttcag gtaaatttcc ttggcctgag
    46021 gatagaaacc aatcccttca agataagttg ccaactcata cagaagatta cttgaatcat
    46081 tttctaaagc tttggcgaaa taatgctcag ccttagttaa atcttgctcc tccaaagcct
    46141 gtaacatctg ttgactattg ttcactcttg acttcctcac cctctaattc atatagacca
    46201 ctgactacct tataccattc gaaaatggct gaaatgacaa ccttagcaga ggcataaacc
    46261 ggaataccaa gtaaaactcc ccagatacca aacatagatc ctgaagttaa caaaacaaag
    46321 agaacattaa taggatggat gtttaattga cttcccaaaa tcaatggaga gacaaaacgg
    46381 ccttcaatag tttgttctac gataaagaca atcactactt tcaaaagcat gactggacca
    46441 gcaatcaaac ccaatactag agcaggaagc atggctagaa agctaccaag ataagggacc
    46501 agatttaaaa taccagcagt aacccccagc gtaaccgcat agcgtagacc aataatcttg
    46561 aagaagatga taaacattac tgctacaata atagccactg tcacttgccc tcgaacatag
    46621 ttggacaact gttgattcac atctgataga acttgtccaa caggttcctt caattttctt
    46681 ggaatgaatt gggtcaaata gttacgcaag cctttcccat cacgcaagag ataaaagagc
    46741 atgaaaggaa cgataatcaa ggcaacaatc acttgagaag ctccgctaat aaaggcactc
    46801 acccagttga ctgcctgaga tgaaacctta cttgccaaaa ctgtagcctg gctagaaaaa
    46861 ttggtcaaaa cttgctctaa ttgaggtctg aaatcatctg gcaggtgctg ggctaccaat
    46921 ccattaacaa tcctatctat atcttctaag taaacaggaa cgtttcttgc aaaggtcaaa
    46981 acctgacgtt gcagatttgg aatggcgact gccaagcccc aaatgataaa gagagcgatg
    47041 ataacaaaga caatagtgat agctataaca cgattaacct tatgcttctc catccaatca
    47101 acaataggat tcaacaaata atataacaaa ccagacaaaa tgactggcaa catcacaact
    47161 gccaaaaagt ctaaaacagg tgaaaataga aaactaatct tacttaaaat aaaaagattc
    47221 aatcccaata ataaggttac taaaaatacc gtaattgcct tgttatctaa aaaccacttg
    47281 aaaaaccaag ataggctaaa atgtttctct ttttgctcca taaatacttc ctttctattg
    47341 ttctctcatt ataccatttt tgaaacaaaa taactctttt ttaaagtgct tacatctaat
    47401 tggatgtctt taatttgctt gtttttgtga tataatagtc ttatctttac acagaggtat
    47461 agtaatgaaa gaaactgttt attttggaac ttatacacgt cgtacttctc aagggattta
    47521 caaggcagac tttgatacag aaactggtca gctttcaaat ctagaacttt ttgcagctga
    47581 gccaagtcca acctaccttg cctttgacca gcaccaacat ttatacactg ttggtagcca
    47641 agacgataag gggggaattg cagcctatca aactgacggg actgtgttaa atcatgttgt
    47701 tgaagaagga gctccccact gttatgttgc tgtcgatgaa aagcgtgatt tggtttacgc
    47761 agctaactat cacaagggac aagtccttgt ttataaacgc caggaagatg gtagtcttct
    47821 acttagtgat atggatcaac acagtggcca aggtccacat gaaaatcaag cttcccccca
    47881 tgttcactat acagatttaa cacctgacca ctatctagtg acctgcgact tgggaactga
    47941 ccaagtcatc acctatgacc tcgatcaaga aggaaaatta tctaagctct atacctatca
    48001 cagcaagcca ggagcaggct cacgccatat cattttccat aaccactata aaatcgctta
    48061 tctcatttgt gaactcaata gtactatcga agttttaatc tacgatggcg ttggcgaatt
    48121 tgaacgtatg caggtcattt caactttacc ggaagcttac gaaggcttta atggaaccgc
    48181 tgctattcat ctctctaaag acggtaaata cctctacgct tctaaccgtg gccatgattc
    48241 tatcgcagta tataccatcc ttgcggacgg tagcttagag ttattagaaa tcgttccaac
    48301 gcatggtcag actccacgtg attttgattt gacacccgac caaaaatttc tcattgttgt
    48361 ccatcaagac tctgacaatg caactgtctt taaacgtaat tgtgacaatg gtcgtctagc
    48421 agaactctcc aacgacttcc atgttcccga agcagtctgc atccgttttg ctccttaaaa
    48481 caccataaaa aatgaacttg gtattttcaa gttcattttt tcttatagtc tatttccgac
    48541 attaatacgg ttaatggcac gttgcaaagc aatcttagca cgacgttctt ggtcaatcaa
    48601 atgtttgtct tgtgcttctt caattgcacg ttctgcacga agtttggcac gttctgcacg
    48661 gctaatatcg atatcacgag cacgttctgc agagtcagcg acgattgtga tcatatcatt
    48721 ggcaatttca ataacgccac cgtttactgc aatccagttc acgtgatctt tatcatcgat
    48781 acgttttacc tttacttcat caactgctaa aaccgcaatc atattttcat gtcgtggcaa
    48841 gatccccatc tcaccatcca gagttcgaac cgatacatag ctggcatggt gatcatagac
    48901 gagaccatct ggtgtcacga tctggacagt taactgagcc ataggtcacc tcttaaaatc
    48961 ccattttttc agcttttgca atcacatctt cgatagaacc tacaccacgg aaggcatctt
    49021 ctggcaagtg gtcgtattta ccatcaagga tttccttaaa gccacgtaca gtttcagcaa
    49081 ctggaacata agaacctggc tgaccagtaa attgttccgc aacgttgaag ttttgtgaca
    49141 agaagaactg gatacgacgg gcgcgagcaa ccaaggtctt ttcttcatca gaaagctcat
    49201 ccataccaag gatagcaatg atatcttgca attcatggta acgttgaagg acacgtttta
    49261 cttcagcagc aactgcatag tgctcttctc caacgatttc aggtgccaag gcacgtgagc
    49321 ttgaagcaag tgggtcaacg gctgggtaga tacccaattg taccaattta cgttccaagt
    49381 ttgttgttga atccaagtga gcgaaggctg ttgctggcgc tgggtcagta tagtcatccg
    49441 ctggcacata gatagcctgg atagaggtta cagaaccctt cttggttgat gtgatacgtt
    49501 cttgcaattg acccatttcc gtagcaagtg ttggttggta accaacggct gatggcatac
    49561 gacccaaaag ggcagatact tctgaaccag cctgagtgaa acggaagata ttatcgataa
    49621 agagaagcac gtcttggcct tccacatcac ggaagtattc agcgattgtc aaaccagtaa
    49681 gggcaacacg catacgtgct cctggtggct cattcatctg accaaagacc atggctgttt
    49741 tctcgataac gcctgattct ttcatttccc agtaaaggtc attcccctca cgagtacgtt
    49801 ccccaacacc agtaaatact gaaataccac cgtgctcttg ggcaatgttg tgaatcaatt
    49861 cttggattaa gacggtttta ccaactccgg caccaccgaa aagtccaact ttaccacctt
    49921 taaggtaagg ggcaagaagg tcaataacct tgatccctgt ttcaaggatt tcagaagagg
    49981 tagacaactc atcaaaagtt ggagcttttt tatgaattgg ctgacgctct gcgtcttctg
    50041 taaaaggagc ttccaaatca atggtatctc ccaaaacgtt gaagacacgt cccaaagttt
    50101 ctttacctac tggtacagag attggacgac ctgtgtccaa tacttccatt ccacgagtca
    50161 acccatctgt tgattccatg gcgatagtac gaaccatacc atctcctaac tccaaggcta
    50221 cttcaaggac gatttttgtt tttctttcgt catttttgta gacgacaagt gcattgttaa
    50281 tctcaggaag tttttcccct gctgcaaaca aaacgtctac aacgggaccg ataacctgag
    50341 caattttacc tgaactcatc tccttctcct attctatata agatactgtc ggttcctagc
    50401 tcaactaggt cctaagttca ttttcatacg agctggacta gagcctattc taaggcacta
    50461 gcacctgcta cgatttctgt aatttcttgt gtaatcgccg cctgtctggc acggttatac
    50521 tgaattgtca aatcattgat gactttctta gcattatctg tcgctgtttg catggctgtc
    50581 atacccgcag cattctcagc tgtcttggca tcgataatgg caccgtaaat catactttct
    50641 gcaaactgag gcaacaactg ctccagaatt tcttctcggc tggtttccaa ttcaaaagtc
    50701 aagctgtact cttcatccgc ttcatttgga tccaagtcaa caatcggaag catttgttcc
    50761 acacgcattt gactggttag cgtattgaca tggtggttgt agcaaacata aagctcatca
    50821 aagagttcat tttggtacat ttcaacagtt tttgaaataa tcttacgaac ttgatcaaag
    50881 ctaggttggt ctgccaagcc acgtaattca taaagtggtt gaataccgcg agccttaaag
    50941 aaatcagctc ccatcccacc gatacagatc atttcaaaac ctttaccgtc tgggtggtat
    51001 tcttctttca actccataac agctttcaaa atagaggaat tataacctcc aaccaaaccg
    51061 cggtctgaag tgataacgat atagcctgtc ttcttcacag aacggctaat caacatcgga
    51121 ttagttgaag caccagctcc attaccatga aggatatctg tcaaaagttt acgcactttc
    51181 tgagcgtaaa cttggaagtt gcgagcagct tcttcagagc gacctaactt agcagccgat
    51241 accatttgca tggcattagt gatttgactc gtattttttg ttgaggcgat ttttgtttta
    51301 atatcattta gagacactgc catctgacac ctctattctt attggaagct agattgattg
    51361 agaaactctg taatcgcagc atccaagact gcttcttctg gcaagtcttt tgtatcacga
    51421 atggtttcca aaatctctgg atgttgagca tcaaagaagg catggaactc ttcctcgaaa
    51481 cgaacaatat catctactgg aacagtatcc aagaaaccat gtgtcaaagc ataaagaatg
    51541 gttacttgtt tctcaacagg taatggtttg tgaacaggtt gtttcaagac ctcaacggta
    51601 cgacgtccac ggttcaactt agcctgtgtt gctgcgtcca agtcagaacc aaacttagta
    51661 aaggcttcca actcacggta tgaagcaagg tcgatacgaa gtgtaccagc aaccttcttc
    51721 atggctttga tttgtgcaga accacctaca cgagatacag atgaacccgc atcgatggct
    51781 ggacgaatac ctgcattgaa gaggccatcg ccaaggaaga tttgtccatc agtgatagaa
    51841 atcacgttgg ttgcgatata ggctgagata tctcctgctt gtgtctcgat aaatggtagg
    51901 gctgtaattg atccaccacc aagttcatca gaaactttag ctgagcgctc aagcaaacgg
    51961 ctgtggagat agaaaacatc ccctgggaag gcttcacgac ctggaggacg acgaagcaag
    52021 agcgatagtt cacgataagc taccgcttgt tttgatagat catcgtatac aatcaaaaca
    52081 tgcttacctt gatacataaa ttcttccgcc atagcaaccc cagtataagg agctaggaag
    52141 agcaatggag atggttgtga agcagaggct gtcacaacga ttgtgtagtc caaggcaccg
    52201 tactgacgaa gtgtttctac ttgcgtacga actgttgatt ctttttgtcc aatcgcgacg
    52261 tagatacaga tcatatcttg atctttttgg ttcaagattg tatcaatcgc aatggttgtt
    52321 ttccctgtct gacggtcacc gataatcaac tcacgttgac cacgaccaat cggtacaagg
    52381 gcgtcaatag ctttcaaacc agtttgcaat ggttctgaaa cagacttacg ttgcataaca
    52441 ccaggagctg gtgcttctac tggacgagtt ttatcagtgt ggatttctcc aagaccgtca
    52501 actggacgac caagcggatc cacaacacga ccaatcagac tttcacctac agggacttcc
    52561 atgattttcc ctgtacggcg gattgtatcg ccttcacgga tatctgtaaa gtcacctagg
    52621 atgataatac caacgtctgt tgactccaag ttttgagcca taccataaga gccgttttca
    52681 aaattcaaca actctccact catgacattt tcaaggccat gagcacgcgc gataccgtcc
    52741 ccgatatagg ttacaacacc tgtttcagtc acatcaaaat tgggtttgaa attttcaatt
    52801 tgttgcttaa ttaaagcgct gatttcttgt gcgttaattg ccaaaagaac accactttct
    52861 atttcaaatt ttctttaaca actttaagtt gttgtttaat actcacatca attgtcttgt
    52921 gattggcaaa aatgacaaaa ccaccaatga gactttcatc gatttgttct tttacactcc
    52981 ttactttcag agacattttt ttctcaatca aagggagcaa acgagtcttc tgttcatcag
    53041 ttagaggatg agcagacgta atcgtcactt caaatcgatt tgtttctttt tcaagtcggt
    53101 tcaagcaatc tacaagcaca tcataaaaaa gatttgctct gtgattgtag gccagaacct
    53161 ggataaagtt ttgtaataaa ggcgacacag aatcttggaa aaaagcaatt gttttttcct
    53221 tatccgactc gtctactgcc acttgtttta aaaaagaagg cagacctgtt ttttcaacaa
    53281 cttgcttgat ttgagtcaag tctgaaaaga tacggtcttc ttctcctttt tcaagtacca
    53341 attggacaaa aggcatgctg tatttttcaa ttacctttac tgttttcttg tccattaagc
    53401 ttctcctagc tgatcgatat actgatcaat gagtgcttta tgggcatgac tgtcaaggtt
    53461 ttgtgagatg attttaccag ctaagctgat ggtcaaatct gcgacctcac ccttaacact
    53521 ctgtaaagct tctactttat tttgagcaat ttcttgattg gctttttctt ttaagtgtcc
    53581 tgcttctagt ttagcatctg ctaagatatt agccttactt tgctcagctg tttcctttgc
    53641 attttcaatg attgtcttag cttctttacg gctaccagcc aattcatctt cgcgtttttg
    53701 agccaatact tctgcttttt gacgggcttc ttcagctctg tcaatatctg aagcaatttt
    53761 ttcagctctt tcttcgaaaa tgcctgtaat attagaccat gcaaattttt taatcaagac
    53821 tagcaaaaga ataaaagagc cagtgattaa aataaaatta ccaattaatt cacctactgt
    53881 tacgtgcatc agttactcct ttctattcct cttcaatatt aatcttattc cctaaataca
    53941 cagatgtcaa aagagtaaaa acataagctt ggatgcagga aataaagaca gaaaatgcag
    54001 tccaagccaa attagctcca aaggctactg gataccaata aatagcttgg tgggaaagaa
    54061 gaagtaacaa actcgtcatg acctctcctg caaagatatt cccaaaaatc cgcaaagcca
    54121 aagataagaa gtttgtaaat tcttccaaga tattcatcgg tatgacaaaa acaggactca
    54181 taaaagattt tatacttttt ttaaatccac gacgacgaac gctttctata tgtgtcaaca
    54241 aaatgacaag aaaagataag gttaagtcat actgtaaatt agcggttggc gaactccacc
    54301 agttagtccc atcgatcgtt tgaatctttg tcattaagcc aaggttattg gcaatcacca
    54361 tgaaaaggaa taaacaaagg aaaaagagtg agtaatcttt catgtagcgc gaaccaatgt
    54421 taggttctgt aaatccaata acaaagtcat agacatactc aagtacattt tgctttcctt
    54481 tgggtttcaa ggtcatattg cggcttgccc aataaataaa gacaaaaata actcccacaa
    54541 tcaacaaagt catggctaac atagtcagat tgaagataac aggaccaata gagatgattg
    54601 gattaatact ttcttccatc taaaatcctc ccttttcttc tcgttccatg tatttatttg
    54661 ataataaatg agaagacaag agttacaaag aaagttcctt caataaaggc aacacctaaa
    54721 aacatcaaac tacgaaactc agaaagcata tctggttggc gtgctactga tttaaacagt
    54781 ccattcatca ataaaccttc accgacagat acgcccatac aggcaataca taagcctaaa
    54841 aatgttaaat tcataacaaa ttctccttta aaataaaatt tacttactta gtgtagtcct
    54901 aaaatttaaa tttgtcaact tttaaccgct attggaagcg tttaataaaa attatttcca
    54961 ttttgctaaa tttcaagt
//
LOCUS       DBEJZV010000013        52245 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.13, whole genome shotgun sequence.
ACCESSION   DBEJZV010000013 DBEJZV010000000
VERSION     DBEJZV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 52245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52245
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.13"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..279
                     /locus_tag="ACL3S0_000939"
     CDS             <1..279
                     /locus_tag="ACL3S0_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HGR1311877.1"
                     /translation="FNSVITTVTGIENRLGAVILAEIRNIHAFDNPAQLQAFAGLDSS
                     IYQSGQIDLAGRMIKRGSPHLRWALIQAAKACARFSPAFKAYLKTKLE"
     gene            complement(580..2469)
                     /locus_tag="ACL3S0_000940"
     CDS             complement(580..2469)
                     /locus_tag="ACL3S0_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGR1311878.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRGA
                     KAADEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2607..4172
                     /locus_tag="ACL3S0_000941"
     CDS             2607..4172
                     /locus_tag="ACL3S0_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR1311879.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4172..4912
                     /locus_tag="ACL3S0_000942"
     CDS             4172..4912
                     /locus_tag="ACL3S0_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR1311880.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(5021..5236)
                     /locus_tag="ACL3S0_000943"
     CDS             complement(5021..5236)
                     /locus_tag="ACL3S0_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311881.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(6107..7357)
                     /gene="ilvA"
                     /locus_tag="ACL3S0_000944"
     CDS             complement(6107..7357)
                     /gene="ilvA"
                     /locus_tag="ACL3S0_000944"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGR1311882.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALVYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7407..7763)
                     /locus_tag="ACL3S0_000945"
     CDS             complement(7407..7763)
                     /locus_tag="ACL3S0_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR1311883.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(8001..8237)
                     /locus_tag="ACL3S0_000946"
     CDS             complement(8001..8237)
                     /locus_tag="ACL3S0_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311884.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(8344..9366)
                     /gene="ilvC"
                     /locus_tag="ACL3S0_000947"
     CDS             complement(8344..9366)
                     /gene="ilvC"
                     /locus_tag="ACL3S0_000947"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR1311885.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9432..9908)
                     /gene="ilvN"
                     /locus_tag="ACL3S0_000948"
     CDS             complement(9432..9908)
                     /gene="ilvN"
                     /locus_tag="ACL3S0_000948"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGR1311886.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9901..11601)
                     /locus_tag="ACL3S0_000949"
     CDS             complement(9901..11601)
                     /locus_tag="ACL3S0_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGR1311887.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11802..13469)
                     /locus_tag="ACL3S0_000950"
     CDS             complement(11802..13469)
                     /locus_tag="ACL3S0_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGR1311888.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALRD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13472..13837)
                     /locus_tag="ACL3S0_000951"
     CDS             complement(13472..13837)
                     /locus_tag="ACL3S0_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR1311889.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13994..14182)
                     /gene="rpmB"
                     /locus_tag="ACL3S0_000952"
     CDS             complement(13994..14182)
                     /gene="rpmB"
                     /locus_tag="ACL3S0_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGR1311890.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(14298..14534)
                     /locus_tag="ACL3S0_000953"
     CDS             complement(14298..14534)
                     /locus_tag="ACL3S0_000953"
                     /inference="COORDINATES: protein motif:HMM:NF013652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR1311891.1"
                     /translation="MCGFFRYFIPKYVSESRVLYLDLDIVVRKSIDELWDLDLTAIPL
                     AAVRDDFYTHNFNSGVLLINNGMWRAENVTQDLI"
     gene            complement(14685..14783)
                     /locus_tag="ACL3S0_000954"
     CDS             complement(14685..14783)
                     /locus_tag="ACL3S0_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HGR1311892.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHLL"
     gene            complement(15038..16582)
                     /locus_tag="ACL3S0_000955"
     CDS             complement(15038..16582)
                     /locus_tag="ACL3S0_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGR1311893.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVSGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16795..17097
                     /gene="gatC"
                     /locus_tag="ACL3S0_000956"
     CDS             16795..17097
                     /gene="gatC"
                     /locus_tag="ACL3S0_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGR1311894.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            17097..18563
                     /gene="gatA"
                     /locus_tag="ACL3S0_000957"
     CDS             17097..18563
                     /gene="gatA"
                     /locus_tag="ACL3S0_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGR1311895.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18563..20005
                     /gene="gatB"
                     /locus_tag="ACL3S0_000958"
     CDS             18563..20005
                     /gene="gatB"
                     /locus_tag="ACL3S0_000958"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGR1311896.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            20134..20694
                     /gene="efp"
                     /locus_tag="ACL3S0_000959"
     CDS             20134..20694
                     /gene="efp"
                     /locus_tag="ACL3S0_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGR1311897.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20716..21105
                     /locus_tag="ACL3S0_000960"
     CDS             20716..21105
                     /locus_tag="ACL3S0_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR1311898.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            21098..21520
                     /gene="nusB"
                     /locus_tag="ACL3S0_000961"
     CDS             21098..21520
                     /gene="nusB"
                     /locus_tag="ACL3S0_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGR1311899.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21544..22290)
                     /locus_tag="ACL3S0_000962"
                     /pseudo
     CDS             complement(21544..22290)
                     /locus_tag="ACL3S0_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234086.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
     gene            complement(22308..22493)
                     /gene="briC"
                     /locus_tag="ACL3S0_000963"
     CDS             complement(22308..22493)
                     /gene="briC"
                     /locus_tag="ACL3S0_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGR1311900.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(22652..23419)
                     /locus_tag="ACL3S0_000964"
     CDS             complement(22652..23419)
                     /locus_tag="ACL3S0_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGR1311901.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WILENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23416..24282)
                     /gene="accD"
                     /locus_tag="ACL3S0_000965"
     CDS             complement(23416..24282)
                     /gene="accD"
                     /locus_tag="ACL3S0_000965"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGR1311902.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24319..25686)
                     /gene="accC"
                     /locus_tag="ACL3S0_000966"
     CDS             complement(24319..25686)
                     /gene="accC"
                     /locus_tag="ACL3S0_000966"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGR1311903.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25698..26120)
                     /gene="fabZ"
                     /locus_tag="ACL3S0_000967"
     CDS             complement(25698..26120)
                     /gene="fabZ"
                     /locus_tag="ACL3S0_000967"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGR1311904.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(26117..26602)
                     /gene="accB"
                     /locus_tag="ACL3S0_000968"
     CDS             complement(26117..26602)
                     /gene="accB"
                     /locus_tag="ACL3S0_000968"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGR1311905.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26605..27840)
                     /gene="fabF"
                     /locus_tag="ACL3S0_000969"
     CDS             complement(26605..27840)
                     /gene="fabF"
                     /locus_tag="ACL3S0_000969"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGR1311906.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27862..28593)
                     /gene="fabG"
                     /locus_tag="ACL3S0_000970"
     CDS             complement(27862..28593)
                     /gene="fabG"
                     /locus_tag="ACL3S0_000970"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGR1311907.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(28627..29547)
                     /gene="fabD"
                     /locus_tag="ACL3S0_000971"
     CDS             complement(28627..29547)
                     /gene="fabD"
                     /locus_tag="ACL3S0_000971"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGR1311908.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29540..30514)
                     /gene="fabK"
                     /locus_tag="ACL3S0_000972"
     CDS             complement(29540..30514)
                     /gene="fabK"
                     /locus_tag="ACL3S0_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGR1311909.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30633..30857)
                     /locus_tag="ACL3S0_000973"
     CDS             complement(30633..30857)
                     /locus_tag="ACL3S0_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR1311910.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30917..31891)
                     /locus_tag="ACL3S0_000974"
     CDS             complement(30917..31891)
                     /locus_tag="ACL3S0_000974"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGR1311911.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31891..32325)
                     /locus_tag="ACL3S0_000975"
     CDS             complement(31891..32325)
                     /locus_tag="ACL3S0_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR1311912.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32419..33204)
                     /locus_tag="ACL3S0_000976"
     CDS             complement(32419..33204)
                     /locus_tag="ACL3S0_000976"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGR1311913.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33529..34893
                     /locus_tag="ACL3S0_000977"
     CDS             33529..34893
                     /locus_tag="ACL3S0_000977"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGR1311914.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34896..35267
                     /locus_tag="ACL3S0_000978"
     CDS             34896..35267
                     /locus_tag="ACL3S0_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGR1311915.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIARKKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35481..36755
                     /gene="serS"
                     /locus_tag="ACL3S0_000979"
     CDS             35481..36755
                     /gene="serS"
                     /locus_tag="ACL3S0_000979"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGR1311916.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36780..37679)
                     /locus_tag="ACL3S0_000980"
     CDS             complement(36780..37679)
                     /locus_tag="ACL3S0_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGR1311917.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVIIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37789..38337)
                     /locus_tag="ACL3S0_000981"
     CDS             complement(37789..38337)
                     /locus_tag="ACL3S0_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGR1311918.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38554..39876)
                     /locus_tag="ACL3S0_000982"
     CDS             complement(38554..39876)
                     /locus_tag="ACL3S0_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGR1311919.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVVLLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39967..40055)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(40219..42555)
                     /locus_tag="ACL3S0_000983"
     CDS             complement(40219..42555)
                     /locus_tag="ACL3S0_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGR1311920.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYTNLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42659..43207)
                     /locus_tag="ACL3S0_000984"
     CDS             complement(42659..43207)
                     /locus_tag="ACL3S0_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGR1311921.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(43204..43506)
                     /gene="zapA"
                     /locus_tag="ACL3S0_000985"
     CDS             complement(43204..43506)
                     /gene="zapA"
                     /locus_tag="ACL3S0_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGR1311922.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43593..44474
                     /gene="rnhC"
                     /locus_tag="ACL3S0_000986"
     CDS             43593..44474
                     /gene="rnhC"
                     /locus_tag="ACL3S0_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGR1311923.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            44478..45092
                     /gene="lepB"
                     /locus_tag="ACL3S0_000987"
     CDS             44478..45092
                     /gene="lepB"
                     /locus_tag="ACL3S0_000987"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGR1311924.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45220..47586
                     /locus_tag="ACL3S0_000988"
     CDS             45220..47586
                     /locus_tag="ACL3S0_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGR1311925.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47634..48917)
                     /gene="tig"
                     /locus_tag="ACL3S0_000989"
     CDS             complement(47634..48917)
                     /gene="tig"
                     /locus_tag="ACL3S0_000989"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGR1311926.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(49111..49470)
                     /locus_tag="ACL3S0_000990"
     CDS             complement(49111..49470)
                     /locus_tag="ACL3S0_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR1311927.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPIIAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(49772..50362)
                     /gene="cbpG"
                     /locus_tag="ACL3S0_000991"
                     /pseudo
     CDS             complement(49772..50362)
                     /gene="cbpG"
                     /locus_tag="ACL3S0_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            complement(50443..50682)
                     /locus_tag="ACL3S0_000992"
     CDS             complement(50443..50682)
                     /locus_tag="ACL3S0_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311928.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(50832..51437)
                     /locus_tag="ACL3S0_000993"
                     /pseudo
     CDS             complement(50832..51437)
                     /locus_tag="ACL3S0_000993"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(51359..51601)
                     /locus_tag="ACL3S0_000994"
                     /pseudo
     CDS             complement(51359..51601)
                     /locus_tag="ACL3S0_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(51602..52234)
                     /locus_tag="ACL3S0_000995"
     CDS             complement(51602..52234)
                     /locus_tag="ACL3S0_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR1311929.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF"
BASE COUNT        15337 a        11941 c         9723 g        15244 t
ORIGIN      
        1 ttcaactcgg tcatcacgac ggttactggg attgagaatc gtttaggggc ggtcatttta
       61 gccgagattc gaaatattca tgcctttgat aatcctgctc aattacaagc tttcgctgga
      121 ctggattctt ctatttatca gtcaggtcag attgatttag ctggaagaat gatcaaacgg
      181 ggttcccctc atctgcggtg ggcactcata caagctgcca aagcatgcgc tcgcttttca
      241 cctgctttta aggcctatct taagactaag ttagaataag gaaaacatta caatgtagcc
      301 atcatccacc ttgcaaaaaa acttatccga accctgtttt atatcctaaa aaagagctgc
      361 catttgacga acaaaaagtg atgtaatttc tgaaattaac acaggattac ctttgaaaaa
      421 atggactttt tcaagggctt tttgccgtgc tctaaaatca tcgccaaatc atcaaattga
      481 aataagaaat agtttagata aaactattga cttttcttat agtttgtctt tcttctatct
      541 tccattatat catacttttt cagtctatgg tagctctctt taaaaggctc cgatactgcc
      601 gccacctccg cctccagaga agccaccgcc agaacttcca cttccagaag atacggagta
      661 ggtacttgct gtatttgcga cactagcata atggctcatt tgcgcgcttg aatgataaaa
      721 catactgtgc cagccataag ctacatagag attgatatct ggattttcaa cttgaatctg
      781 atgaaccttc atcaaatgac taaccttgtc cgcatagcca aataaggttg catagaccaa
      841 gagacgattc caaacaacaa tactttccaa ttcagcctta tccagtcgtg caatctcacg
      901 taacatattt tcaaaactgg tccagagata gtagacctca gctcccgctt catttagaac
      961 accatcacga ttatctagtc gaagcttcca ataatagaaa acagacaaaa ctaaccctag
     1021 aaaaccaagt attggcaaag ggaggtaaag atagccatga acgtctaaac tgtacaagaa
     1081 caaaccaaat ccgataaata ggggcaggat agtcaaggca cccataccca cttgcaaggc
     1141 cttttcccca ccagttaaag gacgataata atctgggagc ccccagaagg aaactcgttt
     1201 tctcactcct tcttgcatct ggttcaatac ctcttcaaaa gaagatttga gttgaagccc
     1261 tcttgcttga atccgtttct catcagcagc tttagctccg cgataaaggc tgtcagatac
     1321 cttgtaatcc gcaaacaaat tggaaagagt ggcttctttt ttgcctgaaa aggctagatt
     1381 tagacagtct ctctcaaatc ttgacaaacc atcttctttc accaatctca agccaactgc
     1441 atctccttct gaaataatag aaacattccc acggtccatc acatctagca aggtagcttg
     1501 aataagttgg tcaaaagtga atttgccagc ccccttgact aagggactca cttcctccaa
     1561 ggaggtcgag tagacagcct ctgataaaac cataggctct aattccattg gtggttcata
     1621 gagacgatga tttttggcat atttgactga aggagtggtc tttcttctat aaataaaata
     1681 gaagcagaca ctcaataaca aggagataga aaggatcgaa gggaggaccc aagtaacaag
     1741 ttgtttactc tgatcttttt ctctaacaat cgagtcttct atcttattaa actcttctaa
     1801 acgattccct ttcaatccct gatccctagc gctagcaaaa tcggtccgag gccagtaggc
     1861 atgcaactca actccacgct tagccggaag attgtctaaa cggatagtat aatcaaggtt
     1921 actcttttca atcgttccct ctctaaaaag tttccctgta tggaaaaaga gtttttcagc
     1981 ccccttgtct ccccttacat gaaattcaaa cttttcaata gactctgaac tatctgtcag
     2041 aggttgccaa tttaattcag caatatcatc ataaaggaaa agtaaatttt ttaagttcca
     2101 gacgaggtca acttcaacta tgtcgccctc ctgacctgga ttatagactc tcacagtata
     2161 accatccgct tcttctgtta cttcgctagt cacatctgct agttctgcac cgtttttcgc
     2221 ggcctgaacc tttggatgag ggtcaatgtc aaacccgcta ggcatcttac cagcacgtcc
     2281 aagtcccacg atttgtccct taaagtcctc ctcaaactgg taaactatct tctgtctaaa
     2341 ctctgccgta ttatctgcat gaatatacaa atccccttga taagagttta tcttgaaatc
     2401 aatggcaaaa acagagagtg gaagaaggca aaacaagcct aacaccagta agaaaaaagt
     2461 ttttttcatc aactaagccc cctttttatc tttcttatca ttatagcatt ttttcgtaag
     2521 taaaggctta cttatgttga aaaattacgc atttttcgat aaaataggag acagttattt
     2581 tttaatagat cagaatagga gaaatcatga gaaaaatata cttatctatt ttcacaagtc
     2641 tcttgctgat gctaggactt gtcaatgttg ctcaagccga tgaatattta cgcatcggga
     2701 tggaagcagc atatgctccc tttaactgga cccaggatga tgatagcaac ggagctgtca
     2761 aaatcgatgg gaccaatcag tatgccaacg gatacgatgt tcaaatcgcc aagaaaatcg
     2821 ctaaggactt aggtaaagaa cctttggttg ttaaaaccaa gtgggaaggt ctagtccctg
     2881 cccttacttc tggtaagatt gacatgatta tcgcaggtat gagtccaact gcagaacgca
     2941 aacaagaaat tgccttttcg agcagttact acactagcga accagttttg cttgtcaaaa
     3001 aagattctgc ctacgcaagt gctaaatctt tggatgactt taatggtgcg aaaatcactt
     3061 ctcaacaagg tgtctacctc tacgacttga ttgcacaaat cccaggtgct aaaaaagaaa
     3121 cagccatggg agacttcgct caaatgcgcc aagctcttga ggctggtgtc attgatgctt
     3181 atgtttctga acgtccagaa gcactgactg ctgaagctgc gaactctaag ttcaagatga
     3241 ttcaagtaga acctggtttc aaaactgggg aagaagatac agctatcgct atcgggcttc
     3301 gtaaaaatga caatcgtatt agccaaatca atgccagcat tgaaaccatt tcaaaagatg
     3361 accaagttgc cttgatggat cgtatgatca aggaacaacc tgccgaagct acaacaactg
     3421 aagagactag cagtagtttc tttagccaag tcgctaaaat tctttctgaa aactggcaac
     3481 aactcttgcg tggtgctggt atcactcttt taatctctat cgtcggaacc atcataggtc
     3541 tcattattgg acttgccatt ggtgtcttcc gtactgctcc tctctctgaa aacaaagcca
     3601 tttatggcct tcaaaaacta gtcggctggg ttctcaatgt ctacattgaa attttccgtg
     3661 gtacgccaat gattgttcaa tcgatggtta tctactatgg aactgcccaa gctttcggga
     3721 tcaaccttga ccgtacactg gctgctatct tcatcgtttc aatcaatacc ggtgcctaca
     3781 tgactgaaat cgtccgtggt ggtatcctag cagttgacaa gggacaattt gaagctgcga
     3841 ctgctcttgg tatgacccat aaccagacca tgcgtaagat tgtcctacct caggtagtcc
     3901 gtaacatcct acctgcaact ggtaatgaat ttgtcatcaa tatcaaagat acatctgtat
     3961 tgaacgttat ctctgttgtc gaactttatt tctcaggaaa taccgtggca acacaaacct
     4021 atcaatactt ccagacattt acaatcatcg ccgtgattta ctttgtcctc accttcaccg
     4081 taacacgtat cctacgcttt atcgagcgca gaatggacat ggatacctat actacaggtg
     4141 ctaaccaaat gcaaacggag gatttgaaat aatgacacaa gcaatccttg aaattaaaca
     4201 cctcaaaaaa tcctatggac aaaacgaagt gctaaaagac atttcactca ctgtccacaa
     4261 gggagaggtc atctctatca tcggaagctc tggaagcgga aaatcgacct tcctacgctc
     4321 cattaaccta cttgaaacac caactgatgg acaaatcctt tatcatggac aaaacgtcct
     4381 cgaaaaaggc tatgacctca cgcaataccg tgaaaagttg gggatggttt tccaatcctt
     4441 taacctcttt gaaaatctca atgttcttga aaacacaatc gtcgctcaga caactgtcct
     4501 aaaacgcgaa cgcacagaag ctgaaaagat tgccaaagaa aacctggaaa aggtcggcat
     4561 gggagaacgc tactggcaag ccaaaccaaa acaactctca ggtggtcaaa aacaacgtgt
     4621 ggccatcgct cgtgccctct ccatgaatcc ggacgctatt ctctttgatg aaccaacatc
     4681 agctctcgat ccagaaatgg ttggagaagt cctcaaaatc atgcaggacc tggctcagga
     4741 aggcttgacc atgattgtcg taacccatga aatggaattt gcccgtgatg tctctcaccg
     4801 tgttatcttt atggataagg gcgtgatcgc tgaagaaggt aaaccagaag acctcttcac
     4861 caatcctaaa gaagaccgaa caaaagagtt ccttcaacgc tatctcaaat aaaaagaaaa
     4921 ggctgcatca accgtgcagt ctttttgctg tcctcaaaat gaaaaggcag attctctatc
     4981 tctactactt gaaggtcaag aatccgccgt tatccaaaga ttaatcttca aatttttcat
     5041 aatttttttc atagaaatca attaagccta gggctgtttc aaatgaaata ttttttactt
     5101 ttgcacgacc ctgcgccaga gcaatgatag acatttcacg cgcattcgtt tctttagaga
     5161 tacggtagcc tgtgattttc ttatcacgaa cccagccaac aactgattct actttttcaa
     5221 agtttgactt agccatgttt ttctcctatt ttcttcttta taatatttaa ttgtatacgt
     5281 ttttactact tttgtcaata aaaaaaacat atattcaacg aaaataatta gttcagaatt
     5341 ttcttacttc ctttttaaat ccgataatat ataggttttg ctagcctcta caccataaat
     5401 atttgctaat aaaactactg tattattacc ctcttaaggt gcgaaattat tcaagttctt
     5461 aaaaaatgct tctctatttc cgtaagatag cttatttctt cgatttaaga actgaagatg
     5521 atagttctaa cctttagaaa tccaagcctt cactagctca aaaactccta tctttcttcc
     5581 tcaataaatc atctgagaga taggtatttc ttatatcctt caaattcatc actcctttgg
     5641 atattgaggt gctagcctag aagcagacac ccgattatct aaaccatcct taatagagat
     5701 gacaagacag ataagctcag ttaattactt atatatcttt ttaatatggt atatttgtca
     5761 acaaaaagaa atcaaatcat accttatact caatgaaaat caaagagcaa actaggaagc
     5821 tagccgcaag ttgctcaaaa cactgttttg aggttgcaga tagagctaac gtggtttgaa
     5881 gagattttcg aagagtatta aagacagtgt gactatgctt gtcaatagat aggaaatcaa
     5941 aatgaaggat ggaaatctga gccaaacatc ataagtgcta taatgaacag aagtaagaat
     6001 tgcacgataa gttttctaaa accataggaa tcgtcccctt tcttcatctt cattatagca
     6061 tatatacatc agttgtacaa ataatatgat atttttttat tagtcctcag acaagcatat
     6121 tataaagcgt ttcattacca tttaagttaa tataagctgg atcaaaacct tccattctac
     6181 gaatcaaacc tgcataatca tgcttatctg ctaaagcgat cccaatcaat actgggcctg
     6241 ttcccttgct agctcgtttg atatactcaa aacgtgtgat atcatcattt ggccccagga
     6301 tatcatttac aaactcacgc aaagctcctg gacgttgtgg gaaattgacc acaaagtaat
     6361 gtttgatacc atcataaacc aaggcacgct cttccatttc tggcatacgg ttgatatcat
     6421 tatttcctcc agaaatgata caacaaatgg ttttcccctt aatatattca gctaaaacct
     6481 ctaaagaggc gatactagcc gctccagcag gttctgcgac tatcccttgc ttagagtaaa
     6541 ggtcaatcaa ggtttcagaa atcaatccct catcgacacc taccaaagtt ttaatatgtt
     6601 gacgagttgc ttcataggtc aactgaccta ccttttgcac agcaatccca tccgcaaatt
     6661 tatcaatttc cttgagtttg actggacctc cagcctcaaa ggcagctttc atggaacgcg
     6721 ctccattcgc ctctactccg ataacctcaa tctctggact tgtttccttg atataggtag
     6781 aaaccccggc aatgagaccg ccaccaccaa caggaaccaa gacagcatca aaatcaatcg
     6841 attcttttcg agcttcttct aaaatctcat aagcaactgt tccttgacct gcttgaacat
     6901 gagcatcatc aaaaggatca ataaaggtac gattttcaga gactgtaaat tcttgagctg
     6961 ctttggctga ggcatcaaag gtatctccaa ctagtttaat agttacaaaa tccccaccaa
     7021 aaaagcgaac ctgaccaatc ttttgttgtg gcgtagtaat aggcataaag atagtagcag
     7081 gaattttcat ttcattacaa gtataggcta ctccctgcgc atgatttccc gcagaagcgc
     7141 agactacccc acgttcacgt tcttccttgc tgagctggga aatggcataa taggcaccac
     7201 gaattttaaa ggagcgaaca cgctgggcat tttctttttt caaataaatc ttagcaccat
     7261 acttctccga taaataatga tcgtaatcca gtggagtatt cacaaccaca ccgttcaaga
     7321 ccttgtgagc cttgattata tcttttgaac ttaacatata aaacctcttt ttctataaaa
     7381 aacagtcact aatgactgtt ttttagttat tcatctccga aaacttcagt aacactttca
     7441 tggtatttat gagccatacg aatcgaaaac tctttaggaa gttcataacg atttgtggaa
     7501 atccaatcat ataaccattc taccaaactt tcttcactat cattacgatg gaagataaaa
     7561 tagtttaaaa tttctttata ttctacatca ttcaaatcca acgtgtctac aaattgacta
     7621 cgaggaacaa aattagaatc taattttctt agttgatctg tcaattctcc caattgtaaa
     7681 tccaactgaa aaaatagttt ttgcagttgc ctatcagttt catcacatcc tgtcttgata
     7741 gaaaacaaat tggtaatatt catatgattt caacccctaa ataagtacat ctaatatccc
     7801 acgaatagct gaagctaaag ttttcgcagt ccagtcattt aaacccgatt ctttcaatcc
     7861 agatgcaata atttgctcta tttgatataa accgccatct atcgtctcat ttattctgcg
     7921 aagaggacct tcaatatagg ataaagcttc tccgaatcta acagctgatt taggtcctaa
     7981 tgatttacca actatatttg ttaatgtttt ttatttctca aaatccattt cgctatataa
     8041 cgagcagatt tagtcgcacc agctctctca aacggagaat gaatttcaag accttcttct
     8101 ctagctattt gtgccaattt gaagaattgt tcaaaggtca tatgcaacct accatcttca
     8161 aaattagcat catcataaat gttaattaca gcattttcat catacgacca atctgcttta
     8221 ttttggtctg ctagcactat taccgacggt gtaattacat tatacaacta gaaccaataa
     8281 taacgatgca atttttctca taatcttttt cataaaatca tctccagcgc tatatatttc
     8341 taattagtta tagattttga atgcatcatc gtcgttttta ccaacgaatg gcattgcttt
     8401 acgcaattct gcaccaactt tttcaatttc aaggttagct gcttgttcac ggtaagcagt
     8461 caattttgga cgtccagctt tatagtcatt tacaaagtca tttgcaaatt taccattttg
     8521 gatgtctgcc aagacagcct tcatattttc tttaacttgt tcagtgatta cacgtggacc
     8581 tgatacatag tcaccgtatt cagcagtgtt tgaaatagat tgacgcattt tcttgaatcc
     8641 accttcatag atcaagtcaa cgatcaattt catttcgtga agaacttcaa agtaagccaa
     8701 ttctggagcg taacctgctt ctgtcaagac ttcgaaacct gcttcgataa gggcagtcaa
     8761 accaccacaa agtacagctt gttcaccaaa caaatcttct tcagtttctt ctttgtaagt
     8821 tgtttcaaga agacctacac gagccgctcc aacaccttta caccagtcca tagcaatgtt
     8881 tttagcattt cctgttgcat cttggtatac tgcataaaga gctggaacac caaatccttc
     8941 ttcgtaagta cgacgtacca agtgtcctgg tcctttagga gcacacatga agacatctac
     9001 atccgcagga actttgataa attcaaagtg gatgttgaaa ccatgggcaa atccaactgc
     9061 gtttccagct tccaagtttg gagcgatttc tgcttcgtac aattcttgtt gaatttcgtc
     9121 tggcgccaag atcatgataa catcagccaa cttagtagct tctgctactg tgtaagtatc
     9181 aaatccatct tcttttgctt tatcaaaaga tttacctgga cgtacaccta taataacgtc
     9241 acgacctgaa tcacgcaagt tttgagcatg cgcatgccct tgtgaaccat aaccgataac
     9301 ggcgattttt ttaccgtcaa gtgctgctac tttaacatct ttttcatatt ccatttgaac
     9361 tgtcatagct tttctctctt ttctattatt tattgccttt taggctggtt taataaattt
     9421 aagttggatt tttaatcgcg ggtaaatcca gttgcacccg ttcgagcaat attgcgaata
     9481 ccgtatgggc gaatgactct caatagggct tcgctctttt ctgcatttcc cgtcatctga
     9541 atggtaatcg agcttggcgc tacgtctacc actgttgcac ggaaaggttg aataatcgct
     9601 aaaatctcag ctctcttctc agctggcgct gacatcttaa ccaaaatcac ctcgcgctcc
     9661 aaatgaggct tgtctgtaat atctcgaatg cgaatcacat caatctgacg attgagctgt
     9721 ttgatgattt gctccacttc atcatgagaa gcaacatcaa taataatagt gatacgcgat
     9781 acattcggat cttctgttgc tccaacagag atgctttcaa tattaacctg acgacgagat
     9841 aggacacctg taaagcgatt gaggactcct gaacgatttt gtagttttgc tgttaacatt
     9901 ctacgcatgg aactgcaccc ccaacatctc atgattactc ttaccagccg gtaccattgg
     9961 taacacctgt tccttacgag aaatatctac ctcaattagc ataggaacat cctcagtgat
    10021 gacttcaagg tcttgagcca aggtctcagg attgtcaaac ttatagtttt taatgccata
    10081 agcctgcgcc atcaattgga aatcaggaag ggtatcaaag accgactctg atgttctgcc
    10141 ttcatagaag gattcctgcc actggcgaac cattccgagt gaatgattgt tcagcataac
    10201 caccttgatt ggcaccttgt aaatattcaa aatagccaac tcctggttag tcatttggaa
    10261 accaccatcc ccaacaaaca agactacttc cttatctggg ttagcaattt tagcaccgat
    10321 tgctgctgga attccaaagc ccattgttcc caaaccacct gaagtcacta actgacgttc
    10381 attttggtag ggataatact gagctgtcca catttggtgt tgaccaacgt ctgttaccac
    10441 aatggcatct ccattcgtca attcaccaat tcgttcaata actgcttgcg gttgaaccac
    10501 acgctctttc ttgtcataag aacgaacacg attcttgtct ttagtgactt tctcaatcca
    10561 cttttcagta ttgttgtgaa ctgttggttc tgctagcaac atttgcaagg ccttcttagc
    10621 atctccaact acaggaatgt ctgcactgat aatcttgcca atctcagctg ggtcaatatc
    10681 aatgtgggca accttagcat tcttagcgaa agtcttagga ttccccgtca aacggtcatc
    10741 gaaacgagaa ccaatactaa tcataaagtc cgcttccgtc atggcaatat ttgctgcgaa
    10801 tgacccgtgc atgcctccca ttccaagaaa gagtgggtga ctcgttgcaa tcgttccttg
    10861 tcccaaaaga ctggttacca ctggaatttg atagcgttct gcaaattcat ttagttccgt
    10921 agcagcctca gcataactaa ttccaccacc agctaacaag actggctttt tagccttgga
    10981 caattgcttc aagattttct tgatttgcat atcattcggc tcaagagtcg gctgataact
    11041 tggtaaattc acttctggtg aataaatgaa gtctgtttct aaagcagata tgtcttttgg
    11101 taggtcaatt acaactggcc ctggacggcc tgtagttgcg atatggacag cttccgtaat
    11161 gatacgcgga atatcagctg tctcacgaac ttggtaattg tacttagtga ttggcatggt
    11221 aattcctacg atgtctgcct cctgaaaggc atccttccca atccctgctc gcgccacctg
    11281 acctgtaaag accaaaaggg gaacgctatc gctcatagca tccgcaatcc ctgtaatggc
    11341 atttgttgct cctggtccac tagtgacgac ggcaacaccc aactttccag ttgatttggc
    11401 ataaccttca gcttcatgca aacaaccttg ctcatggcgc cctagaatgt ggcgaatgcc
    11461 tttaaaatta tatatcgcat cataaaaagg caaaaccgca ccaccaggat aaccaaagat
    11521 ggtatcaact cctaaatcac gaagtgtttc caaaactagg tccgaccccg tcttaggaga
    11581 ttctaaactg attttctcca ttgttcccct ttctttcctc ttaaaaataa cttgttacta
    11641 tcataccatt ttttcaaaat ttttcaagat aaaagaagaa attttctgaa ttttctattt
    11701 taacgtttat ttatgaatgt tatttttgtt tttattaaaa agataccgat ttcatttact
    11761 aaaaaagaaa aaagaactga tttctcagtc cttcattaat cttattccac actaaatagg
    11821 tatgggtaaa caggttgttg accttggtga atctcgactt caacgtcttc gaattcttct
    11881 acgatttctt gagcgatttc attggcaagt tcttcgcttc cgtcttcacc gacatagaag
    11941 gttacgattt cactgtcttc atccaacata tgtttcaagg tttcagtcaa tgtttggtgc
    12001 atatcagggt ttgacacaag aatttttcca tccaccatac ctagattatc gttttcatgg
    12061 atttctaagc catcgatcgt tgtatcacgc acggctgttg tgacgcttcc gctaacgaca
    12121 tctctaagag cagctgtcat acgctcttgg ttttcttcaa tggacttgct tggatcaaag
    12181 gcaagaagac ttgtcatacc ttgaggaaga gtgcgagcct ctaccactac tgctggttgc
    12241 tccaaaactt ctgccgcaga ttgagctgcc atgaagatgt tcttgttgtt tggcaagaag
    12301 atgatgttac gggcattgac ctgttcaaca gccttgataa agtcttctgt tgaagggttc
    12361 atggtttgac cgccttcgat aacataatcc acgccttgag aacagaagat atctgctaga
    12421 cctttaccag ccaccacagc aatcaaagca tactcttttt cttcagccga cttgataact
    12481 tgagtagctt ctttctcaac ctgtgcttcg tgttggttac gcatattgtc aacttttacc
    12541 ttgaccaagc taccatattt gagaccttct tgcataacaa gtcctggatc ttctgtatga
    12601 acatggactt tgacaatttc atcatcgtta acaacgagga gagaatcccc aagctcatcc
    12661 aagtagttac ggaattcatc gtagtcaaaa tctttagcat aggttggacc ttgcttaaga
    12721 gctaccatga tttcagtaca gtaaccaaac gtgatgtcct cagtcgctac gtgaccagct
    12781 acagacttat gatgctctac attgatcatc tcactcatgt tggcaggagt cgctacaaag
    12841 tcctcagatg caatatattc gccagtaagg gctgaaagga aaccttcgta gatgaagacc
    12901 aatccttgac cacctgagtc cacaacgcca acttctttca atactggaag catgtctggt
    12961 gttttagcta gagctgtttt agcaccttcc aaggctgcgc gcatgacttc aacagtatca
    13021 tctgtttgct cagctttttt cttagcaccg atagcagctc cacgagaaac tgtcaaaatc
    13081 gttccttcaa caggtttcat cactgcctta taggcaactt ccacacctga ttggaaggcc
    13141 agagccaagt cttgacctgt taactcgtct ttatccttga tagcttggga aaatccacgg
    13201 aaaagctgag acgtaatcac tcctgagttc ccacgcgcac ccatcaaaag ccctttagca
    13261 agaatgctcg ctacttctcc aactgtagaa gctggcttgt ctgcaacttc tttagcacca
    13321 ttttcaatgg tcattcccat atttgtccca gtatctccat ctggaactgg aaagacgttt
    13381 aatgaattga catattcagc ttgcttattc aagcgagttg atgcagcctg caccatttct
    13441 tgaaataagc tagtagtaat ttttgacacg gttattctcc tacaactttg atattttgaa
    13501 tgtagacatt tacagtctga gcagtaattc caagctggtt ttccaagcta aaggcaacac
    13561 gctcttgaat gttttttgac acttcactaa tctttgttcc gtagcttaac acggtatata
    13621 catcaactgc aatactgcca tcttcggctg cctttacgac gacaccttta gaataatttt
    13681 ccttacctag cagggcttgg aaattatctt tgagggcatt tttactagcc ataccgacca
    13741 caccaaaaat ctcagttgct gctccaccta cgacggttgc aatcacttca tctgttagtt
    13801 cgatttgacc atcttttgta ttaattttta cagtcatcct ttttacctca actagttgat
    13861 actctatttt atcatatttc agcccaagtg taaaagcaga atgatgtatc agcggatatt
    13921 tactctattt ttcaaacgat gttataccca caataaaaga aaaaagaccc taaggtctcc
    13981 tttgctttta ttattaaacg cgttcaactt tacctgattt caaagcacga gctgaagccc
    14041 aaactttttt aggtttacca tcgataagaa cagtaacttt ttgaaggttt ggttttacgg
    14101 cacgttttgt ttggttcatc gcgtgtgaac ggttgtttcc tgatacagtc ttacgacctg
    14161 taaagtaaca tactttagcc attgtgtttt cctcctatta gatctaatat agcggatgtg
    14221 ctagcaccac ataccgtact atgttatcac actttcttgt tttttgcaag ggaattggaa
    14281 gattttttat ttgtgtctta aatcaggtct tgcgtgacat tttctgctct ccacatgcca
    14341 ttgttgatta acagaacacc agaattaaaa ttatgtgtat aaaaatcatc tctaactgca
    14401 gctaagggta tagccgtcaa gtccaaatcc cacagctcat ctatcgattt tcttacaaca
    14461 atatctaaat ccaaatacag tacacgagac tcgcttacat actttggaat aaaataccta
    14521 aaaaagccgc atatgaaagt ccctcaaagg ggagacgata acctttcaga atactactgt
    14581 caatctaaac attcacaatc tcactattca aagtctctag tcttttttcc atcaattgga
    14641 accattctcg cggaaggtca tcattaaaaa cataaaactt aagattataa tagatgaaca
    14701 caaagagatt ttattgttgt ttcaacttta tccatataag cattatctgc acctaagaca
    14761 atcgcttttt tctcttcttt cactctttat ctcatttctt tttattccca tcatatgttt
    14821 ctacgtaacc attattttcg cccattcgtt cgtaaaacca taccagtgga gattttagat
    14881 gaagtcccat tacggtttac aatttttaca ttacgacacg gagttttaca aatcgatttc
    14941 atttgccaaa cgtagttagt aaggcagtta gctagttcgc caaatagcga ctagcgtcca
    15001 acaatttgga actttagttc caattgttgg tactgagtca catcttctcc tctaactcta
    15061 cgtctggata cttgtccgca aaccagcgga gggcaaagtc attttcaaag agaaagactg
    15121 gttggtcaaa acggtctttg gctaagatat tgcgacttga cgacatccgt tcatccaagt
    15181 cctcaggctt gatccaacga acggtctttt tacccattgg gctcatgacc acttccgcat
    15241 tgtattcgcc ttccatacgg tgtttaaaga cttcaaactg gagttgacca acagctccca
    15301 gcatgtactc acctgtttgg taattcttat aaagctgaac ggctccttct tgcaccaatt
    15361 gctcaatccc cttgtggaag gatttttgct tcataacatt cttagcagaa actttcatga
    15421 aaatttcagg agtaaaggtt ggcagtggtt caaattcaaa cttgtttttt ccaaccgtca
    15481 aggtatcccc aacctgataa gtaccggtat cgtaaacccc gataatatca cctgatacgg
    15541 cattggtcac attctcacga ctctccgcca taaactgggt aacattagat agtttggcac
    15601 ccttaccagt acgagggaga ttgacactca tgccacgctc aaattcgcct gatacgatac
    15661 ggacaaaggc aatacggtca cggtgacgag gatccatgtt ggcttggatt ttaaagacaa
    15721 agcctgagaa atccttgtca taaggatcca caatttcacc gtctgttttc ttgtgaccat
    15781 gtggttctgg agcaaacttg aggaagattt caaggaaggt ctgcacacca aagtttgtca
    15841 gggctgaacc gaaaaagaca ggcgtcaatt ctccagccag aatagcttcc tctgaaaact
    15901 cattcccagc ttcatttaaa agctcaatgt catccttgac ttgctcgtag aaaggattgc
    15961 taccaaagag tttgtccccg tcttctagac tggcaaaacg ctcatcccct ttgtaaagct
    16021 ctaaacgttg gttatagagg tcatacaagc cctcaaaggc tttccccatc ccgataggcc
    16081 agttcatagg gtagctagca atgcccaaga tttcttccaa ttcttgcaag agatccaaag
    16141 gctcacgacc gtcacggtcc agcttgttca taaaggtaaa aactggaatg ccacgatgtt
    16201 tcacaacctc aaacaatttc ttggtttgag cctcgatccc cttggcagag tccacgacca
    16261 tgaccgcagc atccaccgcc atcaaggtac gataggtatc ttctgagaag tcctcgtgcc
    16321 ctggcgtgtc taagatattc acgcgcttgc cgtcgtagtc aaattgcata acagatgaag
    16381 taacagaaat cccacgttgc ttctcgatat ccatccagtc agatttagca aaagtccctg
    16441 ttttcttccc ttttaccgta ccagcctcac gaatctcacc cccaaagtag agtaactgct
    16501 cagtgatggt tgttttcccc gcgtccgggt gggagataat ggcaaaggta cgacgtttct
    16561 taatttcttc ttgaatattc ataagttctc tttctttgat tctctatttt tcttgtttca
    16621 atagctgaga atgattttta cattggattt taccattcct ttcaacactc cattatatcg
    16681 gattttagca tttttttcaa tttctatttc ttttcacttc cccctccctt atttatagga
    16741 aaatatggta aaatagaaca gactaaaaat catcatttca cgaaaggatg caagatgaaa
    16801 attacgcaag aagaggtaac acacgttgcc aatctttcaa aattaagatt ctctgaaaaa
    16861 gaaactgctg cctttgcgac caccttgtct aagattgttg acatggttga attgctgggc
    16921 gaagttgaca caactggtgt cgcacctact acgactatgg ctgaccgcaa gactgtactc
    16981 cgccctgatg tggccgaaga aggaacagac cgtgatcgct tgtttaaaaa cgtacctgaa
    17041 aaagacaact actatatcaa ggtgccagct atcctagacg atggaggaga tgcctaatga
    17101 cttttaacaa taaaactatt gaagagttgc acaatctcct tgtctctaag gaaatttctg
    17161 caacagaatt gacccaagca acacttgaaa atatcaagtc tcgtgaggaa gccctcaatt
    17221 catttgtcac catcgctgag gagcaagctc ttgttcaagc taaagccatt gatgaagctg
    17281 gaattgatgc tgacaatgtc ctttcaggaa ttccacttgc tgttaaggat aacatctcta
    17341 cagacggtat tctcacaact gctgcctcaa aaatgctcta caactatgag ccaatctttg
    17401 atgcgacagc tgttgccaat gcaaaaacca agggcatgat tgtcgttgga aagaccaaca
    17461 tggacgaatt tgctatgggt ggttcaggtg aaacttcaca ctacggagca actaaaaacg
    17521 cttgggacca cagcaaggtt cctggtgggt catcaagtgg ttctgccgca gctgtagcct
    17581 caggacaagt tcgcttgtca cttggttctg atactggtgg ttccatccgc caacctgctg
    17641 ccttcaacgg aatcgttggt ctcaaaccaa cctacggaac agtttcacgt ttcggtctca
    17701 ttgcctttgg tagctcatta gaccagattg gaccttttgc tcctactgtt aaggaaaatg
    17761 ccctcttgct caacgctatt gccagcgaag atactaaaga ctctacttct gctcctgtcc
    17821 gcatcgccga ctttacttca aaaatcggcc aagacattaa gggcatgaaa attgctttgc
    17881 ctaaggaata cctaggcgaa ggaattgatc cagaggttaa ggaaacaatc ttaaacgcgg
    17941 ccaaacactt tgaaaaattg ggtgctatcg tcgaagaagt cagccttcct cactctaaat
    18001 acggtgttgc cgtttattac atcatcgctt catcagaagc ttcatcaaac ttgcaacgtt
    18061 ttgacggtat ccgttacggc taccgcgcag aagatgcgac taatcttgat gaaatctatg
    18121 taaacagccg tagccaaggt tttggtgaag aagtgaagcg ccgtatcatg ctgggtactt
    18181 tcagtctttc atcaggttac tacgatgcct actacaagaa ggctggacag gtccgtacac
    18241 ttatcattca agatttcgaa aaagtcttcg cggattacga tttgattttg ggtccaactg
    18301 ctccaagtgt tgcctatgac ttggattctc tcaaccatga cccagttgcc atgtacttag
    18361 ccgacctctt gaccatacct gtaaacttgg caggactgcc tggaatttcg attcctgctg
    18421 gattctctca aggtctacct gtcggactcc aattgattgg tcccaagtac tctgaggaaa
    18481 ccatttacca agctgctgct gcttttgaag caacaacaga ctaccacaaa caacaacccg
    18541 tgatttttgg aggtgacaac taatgaactt tgaaacagtc atcggacttg aagtccacgt
    18601 agagctcaac accaattcaa aaatcttctc acctacttct gcccactttg gaaatgacca
    18661 aaatgccaac actaacgtga ttgactggtc tttcccagga gttctaccag ttctcaataa
    18721 aggggttgtt gatgccggta tcaaggctgc tcttgccctc aacatggacc tccacaaaaa
    18781 aatgcacttt gaccgcaaga actacttcta ccctgataat cccaaagcct accaaatttc
    18841 tcagtttgat gagccaatcg gttataacgg ctggattgaa gtcgagctag aagacggtac
    18901 gaccaagaaa attggtatcg aacgcgccca cttagaggaa gacgctggta aaaacaccca
    18961 cggtacagac ggctactctt acgttgacct taaccgccaa ggggtacctt tgattgagat
    19021 tgtatctgaa gccgatatgc gttcgccaga ggaggcctat gcttatctga cagccctcaa
    19081 ggaagttatc cagtacgctg gcatttctga cgttaagatg gaagaaggtt ctatgcgtgt
    19141 ggatgccaac atctcccttc gcccttatgg tcaagaaaaa ttcggtacca agactgaatt
    19201 gaagaacctc aactccttct caaacgttcg taaaggtctt gaatacgaag tccaacgcca
    19261 ggctgaaatt cttcgctcag gtggtcaaat ccgccaagaa acacgccgtt acgatgaagc
    19321 taacaaaaca accatcctca tgcgtgtcaa ggaaggggct gctgactacc gctacttccc
    19381 agaaccagac ctacccctct ttgaaatttc tgacgagtgg attgaggaaa tgcggactga
    19441 gttgccagag tttccaaaag aacgtcgtgc gcgttatgta tctgaccttg gtttatcaga
    19501 ctacgatgct agtcagttga ctgctaataa agtcacttct gacttctttg aaaaagctgt
    19561 tgccctaggt ggtgatgcca aacaagtctc taactggctc caaggggaag tcgctcagtt
    19621 cttgaatgct gaaggtaaaa cactggaaca aatcgaattg acaccagaaa acttggttga
    19681 aatgattacc atcatcgaag acggtactat ttcatctaag attgccaaga aagtctttgt
    19741 ccatctagct aaaaatggcg gtggcgcgcg tgaatacgtg gaaaaagcag gtatggttca
    19801 aatttcagat ccagctatct tgatcccaat catccaccaa gtctttgccg ataacgaagc
    19861 tgctgttgcc gacttcaagt caggcaaacg taacgccgac aaggccttta caggattcct
    19921 tatgaaggca accaaaggcc aagccaaccc acaagttgcc cttaaactac ttgcacagga
    19981 attggcgaag ttgaaagaaa actagacaga acaaaaccag ccctaaggtt ggttttttct
    20041 tctctaccaa ctcccaataa ctattttggc tttatttcca gagtatttta tggtaaaatg
    20101 aagagtaata atatttatta aagaggtaaa aacatgattg aagcaagtaa attaaaagct
    20161 ggtatgacct ttgaaacagc tgacggcaaa ttgattcgcg ttttggaagc tagtcaccac
    20221 aagccaggta aaggaaacac gatcatgcgt atgaaattgc gtgatgtccg tactggttct
    20281 acatttgaca caagctaccg tccagaggaa aaatttgaac aagctattat cgagactgtc
    20341 ccagctcaat acttgtacaa aatggatgac acagcatact tcatgaatac agaaacttac
    20401 gaccagtacg aaatccctgt agtcaatgtt gaaaacgaat tgctttatat ccttgaaaac
    20461 tctgatgtga aaatccaatt ctacggaact gaagtgatcg gtgtcaccgt tcctactact
    20521 gttgagttga cagttgctga aactcaacca tctatcaaag gtgctactgt tacaggttct
    20581 ggcaaaccag caacgatgga aactggactt gtcgtaaacg ttccagactt catcgaagca
    20641 ggacaaaaac tcgttatcaa cactgcagaa ggaacttacg tttctcgtgc ctaatctcta
    20701 gaaagaggtc attctatggg aattgaagaa caacttggcg aaatcgttat cgccccacgt
    20761 gtacttgaaa aaatcattgc tatcgctact gcaaaggtag agggtgttca ctctttttca
    20821 aacagatcag tgtctgatac cctttcaaaa ctttcactcg gccgtggcgt ttatcttaaa
    20881 aacgtggacg aagaactcac agcagatatc tatctctacc ttgagtacgg agtaaaagtt
    20941 cctaaggtag cggttgctat ccagaaagct gtcaaagatg ccgtccgtaa tatggctgat
    21001 gtagaactcg ctgctatcaa tattcacgtt gcaggtatcg tcccagataa aacaccaaaa
    21061 ccagaattga aagatctatt tgacgaggac ttcctcaatg actagtccac tattagaatc
    21121 tagacgccaa ctccgtaaat gcgcttttca agctctcatg agccttgagt tcggtacgaa
    21181 tgtcgaaact gcttgtcgtt tcgcctatac tcatgatcgt gaagatacgg atgtacaact
    21241 tccagccttt ttgatagacc tcgtttctgg tgttcaagct aaaaaggaag aactagataa
    21301 gcaaatcact cagcatttaa aagtaggttg gaccattgaa cgcttaacgc tcgtggagag
    21361 aaacctcctt cgcttgggag tttttgaaat cacttcattt gacactcctc agctggttgc
    21421 tgttaatgaa gctatcgagc ttgcaaagga cttctccgat caaaaatctg cccgttttat
    21481 caatggactg ctcagccagt ttgtaacaga agaacaataa aaagaaaaag tgtttgatag
    21541 atatcaaaca ctttttcttt gcctcccact atctaaaaaa tgataataga tataattgta
    21601 aacaaaaatc cagataggtt ttgcatgatt gagaaagtta aaaaaactat ggcagagaat
    21661 cgttaatctc agattgtcgg tagaacgata aacaagggca aaaaagaaac caatcagact
    21721 ataatataat aaactaattg gatctctgtg agatagtatc aaatggctaa tcccaaagat
    21781 aaggcctgat aagatgacat ctaaatagta ctttgactta ggaaagaagg tattcatcaa
    21841 ataccctcta tcaagagtct cctcaaaaac aggaccgatg attacaagca ggacaaaaga
    21901 taagatagtc gataaaaagg ttggttgtcc atttgaaaga accacggtaa aatactcatc
    21961 atgaatattc ctatggttaa tcaaatgagc atagcgtgcc taaaaattac cgagaatctg
    22021 ataaaccaca tacgttgcaa ataagtagaa gacaaatgac cagttccagc tctttttttc
    22081 aaagataaag agcatctttt tcttttttaa cctccaaatc aatagaagga aacttcccac
    22141 taataccatt gttaaaataa gagaatagac atcagctcct aaccctaaaa tgatcgtcac
    22201 atacaatcca attgtttgtg gtaaataggt agatagtaaa ataataagca aaaatattcc
    22261 aaattgtctt agtttttttg tgtttctcat cgtacttttt tgaaagatta ccctgctcgg
    22321 aagccgtact tccaagcatc tatataagaa ttaagtgccc cttgcctcat atagggagca
    22381 aattctctat aatataacca tctactatat ccatcttccc aaacagcaag accacctgaa
    22441 gtttgctcca agtcctcagt tgaaagaact gtaaatgtat ttgtacctgt cattgcaagt
    22501 accttcttaa aatagattgt tgtaggctca catttatagt atatttcttt ttttgtctat
    22561 tttatagtct atctcctcaa ctgtcaattt ttcaacctga attgcatttt tccataaaaa
    22621 atgagacctt tctagtctca tttagtcatt cttagtattt tctaaatcgt tgatagcgtt
    22681 cttccagcaa ctcttctagc ggtttttgtg aaagtctagc cagctccgtt tggagttctt
    22741 ttttgacact cttaatcagt tctttactag aaagtcctac ttcagaaatc accttatcca
    22801 ccacgtccat ttctaacagt tcatgcgaag tgattttcat cagttctgct gcttccatgg
    22861 cgcgagtacc gtccttccat aaaatggaag caaagccttc tggactgaga atggcataga
    22921 tagaattttc cagtatccag acacggtccg cgacagctag agccagagcc ccgcctgaac
    22981 caccttcacc gataataatg gcgataatag gaactttcag gtcactcatt tccatgagat
    23041 tgcgagcgat agcttcccct tgaccacgtt cttctgctcc gacaccagga taagcacctg
    23101 ctgtattaat aaaggtcaca actggacggc caaatttctc agcctgtttc atcaaccgca
    23161 gtgcctttcg gtagccttct ggatgtggtt ggccaaaatt ccgtttgagg ttgtcttgca
    23221 aactcttgcc tttttggata ccaacaactg ttacagcttg gtctccaagc caaccaatac
    23281 caccaacaac tgcaccatca tcacgaaaag aacggtcacc atgtaattgg ataaattcat
    23341 caaaaatgcc tgtcgcaaag tccaaggttg tcaagcgact ctgctcacgc gcttctctga
    23401 ctatttttgc aatattcatc taggactccc tccatgcaat ctgactaggc tagcaatcgt
    23461 atctggtaag tctcttcttt tgacaatagc atccacaaag ccatgttcta ataggaattc
    23521 tgccttttgg aaatcctcag gcaagctttc acgaaccgta ttttcaatca cacgacgccc
    23581 agcaaaacca accaagctct gtggttcagc cagaatgata tcgccttcca tagcgaaaga
    23641 agctgtcaca ccaccagtcg ttggatctgt caaaatggtc aggtaaaaga gaccagcatt
    23701 tgaatggcgt ttaaccgccg cagagatctt agccatctgc atgagactca tgattccttc
    23761 ctgcatacgg gctccaccag aggctgtgaa taggacaact ggcaattttt cgacagtcgc
    23821 atactcaaac aaacgagtga ttttttcacc tacaaccgta cccatagaag ccatgataaa
    23881 gttagaatcc ataatcccaa gagccacagt ctgaccttta ataagagcag ttcctgtcac
    23941 aacggcttca tgcagacctg ttttttcacg catagatgcc agtttctttt ggtaaccagg
    24001 gaaatgcaag ggatccttgc tttcaatccc tgtaaacaat tctttgaagg ttcccatatc
    24061 aatcgtcaaa gccaagcgtt cttgggcaga aatacgaaag gtatagctac agtgcggaca
    24121 gatacgttca cttcccagat ccttctgata gatggtatgc ttacagcctg gacactggga
    24181 aaataattca tctggaacct ctggcttagc ttgaggtttt tccctaaccg aacgattggg
    24241 attgattcga atatacttat cttttttact aaatagagcc attgattccc cttttcggtt
    24301 taaactctta aagtcatttt attctttttc ttgatattta ggtaagaagg tttccatcaa
    24361 gaaggaagta tcataatccc cagcaatgac attgcgatct gaaatgaggt caagctggaa
    24421 atctgcattg gtctgcactc cttcaatctc taattcatag agggcacgtt gcattttcat
    24481 caaggcgtca aaacgatttt cgccgtgtac tatgattttg gcaatcatac tatcataata
    24541 aggcggaatg gtataacctg gataaactgc tgaatccacg cgcaagccaa ctccaccact
    24601 tggcagatag agattagtaa tcttacctgg acttggagca aagttaaagg ctgggttttc
    24661 tgcattgata cgacactcga tggcatgacc acgtaggaca atatcttctt gcttaacaga
    24721 caaaggctga cctgccgcaa tgcaaatctg ttccttaacg atatcaacac ctgaaacaaa
    24781 ctctgttact ggatgttcta cctgaacacg agtattcatc tccatgaaat agaaattgct
    24841 acttgcttca tcaagaagaa attcaatggt tcctgcattc tcatagccaa caaactctgc
    24901 cgctcgaaca gcagcagcac ctatttcatg acgcagcgtt tttccgattg caatcgaggg
    24961 actttcttcc aaaacctttt ggttattcct ttgaagagaa caatcccgtt cacccaagtg
    25021 aatcacatgt ccatgctcat cacctaggat ttgaacctca atgtgccgag ctggatagat
    25081 aacccgttct atgtacatgg caccattgcc ataattggcc ttggcctcac tagaggcagt
    25141 ttcaaaggca gaaacgaggt catctggttt ttcaacctta cgaatccctt taccacctcc
    25201 acctgctgaa gccttgagca taacaggata gccaattttt tcagcaacaa tcaaagcttc
    25261 ttcagagtta tgcacttctc catctgaacc tggtataaca ggcacacctg ctttaatcat
    25321 ctgagcacgc gcattgatct tatcccccat catatccata acatgaccag atggaccgat
    25381 aaacttgata cctacttctt cacacatggt cgcaaatttg gaattttcac tgagaaatcc
    25441 aaaaccaggg tgaatagctt ctgcctcagt caagactgca gctgatagaa ctgcattaat
    25501 attgagataa gactctgttg ccttgccagg accaatacaa actgcttcat ctgccaaaag
    25561 cgtatgaaga gcttccttat cagcagttga ataaaccgct accgtcgcaa tccccaattc
    25621 acgtgccgca cggataatac gaaccgcaat ttcaccacga ttggcaatta aaatttttcg
    25681 aaacatggag aacctcctta gttcccaatt gcaaaagtaa ggataccact ggctgcaagc
    25741 ttgccatcca cttcagcctt tgcttcaacc acagctatgg tgccacgacg ttttacaaaa
    25801 gtcgctgtca taaccaattg gtcgcctggt acaacttgct tcttgaactt aaccttgtcc
    25861 ataccagcgt aaaagaccag ttttccttta ttttcaggtt ttgataactc caacacacca
    25921 gcagtttgcg ccaaggcttc cataatcaga acacctggca taactgggta ttgaggaaag
    25981 tggccgttaa agaaaggttc gttaatggtc acatttttga tagcaacaat ggtatcctcg
    26041 ctcacttcca agacacggtc cactagaagc ataggataac ggtggggaag agcttctttg
    26101 attccttgaa tatcgatcat ttgatacgta ccaatccttt accaaactca accatttctt
    26161 cgttagagac gagaatttcc gttaccacac catccttagg agctgggatt tcattcatga
    26221 ctttcatggc ttcgataatt accaatgttt gacctttttt gacactatca ccaactgtaa
    26281 cgaaggcagg tttatctggt ccagcagcca agtaaaccac tccaacaagt ggactctcta
    26341 caagatttcc ctcactagcc acacttgctt cagctggagc tggaacttct tctgctacag
    26401 tctctgctgg agcagatgta ggagctactg gactcggtgt tgctagaacg ggtgctggag
    26461 cgacttgagt tgcaacttca ggcacaggtc ttgcttcatt cttgctaaac tgcaactcat
    26521 ccgtcccatt tttataagaa aattctctca aacttgactg gtcaaattga gtcatcaagt
    26581 ctttaatatc gtttaaattc atacttatct attctcccaa cgtttgaaag caagaactgc
    26641 attgtggcct ccaaaaccaa aagtatttga aatagcgtat ggaatttctt tctccaagcc
    26701 ttgtccataa acgacattag cttcgatata atctgatact tcacttgtcc cagctgtcat
    26761 tggtacaaag ttatgacgca tagcttcgat ggtgacgata gcttctactg cacccgcagc
    26821 ccccagtaaa tgtcctgtaa aagacttggt tgatgataca ggtacttcct taccaagaac
    26881 agctacgata gctccacttt ctcctttttc attggcagga gttgacgttc cgtgagcatt
    26941 gacataggct acttgctctg gagaaatctc agcttcttcc aaggctagtt tgatggcctt
    27001 gatagctccc tgaccttctg gatgtggaga agtcatgtgg taggcatcac aagtatttcc
    27061 gtaaccaacc acttcagcca ggatagtagc tccacgtttt tcagcgtgtt caaggctttc
    27121 tagaaccaac atccctgaac cttcacccat aacaaaccca ttgcgatcct tatcaaatgg
    27181 gatcgaagca cgagttggat cctctgtagt agagagagct gttaaggctt ggaaaccagc
    27241 gatggcaaaa ggtgtgatag aagcttctgt tcctcccacc aacatcacat cttggaaacc
    27301 aaacttaatg gagcggaagg catccccaat cgcatcattt gatgaagagc aggcagtatt
    27361 gatagattta caaacaccgt ttgcaccaaa acgcatggct acattcccag aagccatatt
    27421 tggtaaagct tttggaagag tcattggttt gacacgtttg ggtccttttt catgaaggcg
    27481 aagtacctga tcttcaattt ccttgattcc accaatacca gatgcaacga taacaccaaa
    27541 acgatcccta ttaagagcct ctacatcaag attggcatga tttacagcct cttgggctgc
    27601 atacaaggca tataaagaat agttatcaaa acggttggta tcttttttta caaagtattt
    27661 atcgaacgga aaatcttgga tttctgccgc attatgcaca tcaaagtcac tatgatcaaa
    27721 ttttgtaatg ccaccaatgc cgattttccc agttgctaaa ctattccaaa attcttctgg
    27781 tgtatttccg attggagatg ttactccata acctgttacc actactcgat ttagtttcat
    27841 tcttttcacc tctagctttc gctacatact taagccacca tcaatggcaa tcacttgacc
    27901 agttagataa tcttggcctg ctaaaaatac tgtcaaatct gcaacctgct ctgcctgccc
    27961 aaattctttc atcggaatct gagctagtgt agcttcctta atcttatctg ataagatagc
    28021 tgtcatatca gactcaatca ttcctggagc aatcacattg actcgtatat tccgactagc
    28081 gacctcgcgt gccacagact tggtaaagcc aatcaagcca gccttagaag cagcatagtt
    28141 agcttgacca atattcccca tcaaaccaac aacactagac atattaatga tagcaccttc
    28201 tctggctttc atcatcggtt tcaagactga ttgtgtcata ttaaaggcac cagtcagatt
    28261 gaccttgagc actttttcaa aatctgcttc tgtcatcttg agcataagag tatcttgggt
    28321 aatccctgca ttgttgacca aaacatctac tgaacccagt tctgcaatag cttgatcaat
    28381 catacgctta gcgtctgcaa aatctgatac atctcctgaa atgggaacca ccttgatacc
    28441 atagtttgaa aactcagcga gcaattcttc tgagattgcc ccacgactgt ttaagacaat
    28501 gttggctcct gcttgagcaa acttgtgggc gatggcaaga ccaattccac gactcgaacc
    28561 tgtaataaag atatttttat gttctagttt catttttttc ctttcaaaac ttctacttat
    28621 tttagtctat ttttctaaaa gtgctactaa actcgcttga tcttccacat gagctaagtg
    28681 agcagtttga tcaatttttt taacaaaacc tgacaagact ttccccggtc caatctcgat
    28741 aaagttgctt atgcctgctt cttgcatgac cccaatactt tcatagaaac gaacgggttc
    28801 cttgacctga cgcgtcaaga gctgagcaat gtcctctttt tgcatcacag cagcttctgt
    28861 attgccgact aggggacaag taaaatctga aaaacttacc tgagctagag tttcagctag
    28921 tttctggcta gctggctcaa ggagagcggt gtgaaaggga cctgacacct taagaggaat
    28981 caagcgtttg gcacctgctt cttgcaaaag ttcaaccgct cgatcaactg caaccacttc
    29041 tccagcaatg acgatttgtg caggtgtgtt atagttggct ggagtaacca ctccaagttc
    29101 agaagctttt tgacaggctt cttcaatgac ctctactggc gtattgagaa ctgctaccat
    29161 cttgccagag tcagcaggag ccgcttcttc catataggct ccacgcttag ctaccaaggc
    29221 aaccgcatct tcaaaatcca aggcgccgct tgccaccaag gcagagtatt ctccaagaga
    29281 caaaccagca accatatcag gctgatagcc cttttcttgc aataaacggt agatagcaac
    29341 cgaagtcgct agaatggctg gttgcgtata gcgggtctga ttgagtttgt cttcttccgt
    29401 atcgatgaga taacgcaaat cataacctag cacctgactc gctcgatcaa tcgtttcttt
    29461 aacaatcgga tactgatcat agaaatcccg tcccatccct agatactggg caccttgacc
    29521 agcaaataaa aaggctgttt tagtcatttc ttacaactcc tgcccagcga gaggcttctt
    29581 cttgaatttt cttagcggct ccgtaataca aatcttttag gatttcttca gctgtttctt
    29641 ctttagaaac aagccctgcg atttgacctg ccatgacaga gccaccatcc acatcaccgt
    29701 gaacaactgc tttggctagg gcacctgctc ccatttgttc aaagatttct aaatcaggat
    29761 cttcctgctt aaaggcatct ttttcagcca gttcaaaatc tctagtcaac tgatttttaa
    29821 tagcacgaac agcatgacca aagtgctgag ctgaaatcgt agtatcaata tcccttgctt
    29881 ttaaaatttt ctccttgtag tttggatggg cattcgactc ttttgcaact acaaaccgtg
    29941 tccccacctg tacagcctct gcacctagca taaagccagc cgcagcacct tcaccatccg
    30001 caattcctcc tgcagcaata acaggaatag atatagctgt ggctacctgt cgcaccaagg
    30061 tcatggttgt taatttaccg atatgccccc cagcttccat tccttctgca ataacagcgt
    30121 ctgcaccgat tttttccatg cgtttagcta aagcgacact aggaacaaca ggaataacga
    30181 ttatcccagc ttcatggaaa cgttccatat acttgcttgg atttcctgct cctgttgtga
    30241 caactttaac accttcttca ataacgagat ccacgatatc ttccacaaag ggagataaga
    30301 gcatgatgtt gaccccaaag ggtttatcag tcaatgattt gattttatca atattggcct
    30361 tgacaacttc tttcggggca tttcccccac cgataattcc taatcctcca gccttggaaa
    30421 cagcccctgc caaatcacca tcagcaaccc aggccatccc tccttggaaa ataggatagt
    30481 caatcttcaa taattctgta atacgcgttt tcatagtgcc tccaaccttc cttgcttacg
    30541 taatagttcg atttcaccat aatttgacag tcaaactatt acctaaacaa gagggagtgg
    30601 gtttctccct actccttcta ctaatattct gcttattttg cttgctcttc aacgtaagca
    30661 accaagtcac caactgtttt caagtcattt tctgcttcga tttggatatc aaaagcatct
    30721 tcgatttctg agattacttg gaacaagtcc aatgaatctg cgtccaaatc atcaaaagtt
    30781 gattcaagtg ttacttctga tgcgtctttt ccaagttctt caacgataat ttcttgtact
    30841 ttttcaaata ctgccatgat aggactcctt taaaataaat agttttttta taacaatgtg
    30901 ttcaccacat gattacctaa attgtaagaa tgagcgtgcc ccaggtcaag cctccaccga
    30961 agcctgatag aagaacagtc tggctaccat ctaaagggat gagaccttgt tctacacact
    31021 ctgaaagtaa aatcgggata ctggctgcac tggtattgcc atattccatc atattggctg
    31081 gaagtttggc tcggtcaaca ccaatttttc tagccatctt atccaaaata cggtcattgg
    31141 cttgatgaag tagcagataa tccaagtctg tcacctctat aggagattca tcaatagtct
    31201 gcttgataga cttggctaca tctcgaatgg caaaatcaaa gactgtgcgt ccatccatct
    31261 tcaaaaacga atctgcactt tcttgatctg aaaatggaga atgcaaacct gaatgcccat
    31321 aagttaaaca ctcgctgcga cttccatcgc tattgagact ctcagctaag aaatgctctt
    31381 gctcgctagc ttctaacaag acaccaccag caccatctcc aaacaacaca gctgttgatc
    31441 gatccgacca atcgactgcc ttagagaggg tttcactacc aatcaccaag cctttttgaa
    31501 agcgaccaga agcgataaac ttttcagcag ttgaaagagc aaatacaaat ccactgcaag
    31561 ctgcggttaa gtcaaaagca aaggctttat tagcgccaat attagcttga acacgagcag
    31621 ctgtagaggg catcatcgaa tctggagtaa tggtagctag gatgataaaa tccagttctt
    31681 ttcctgttat tccagctttt gccatcagtt tcttagcaac ctctgtagcc aaatcactgg
    31741 tagattctgt tcttgaaata tgcctttgtc gtattcccgt tcgacttgaa atccactcat
    31801 cattggtatc cataatctga gccaagtcgt gatttgtaac cacttgctct ggcacataat
    31861 gagcaacctg acttattttt gcaaaagcca ttatttcaaa tcctccaaaa attggtaaag
    31921 attagtcaaa cctttaccca tgacagcaat ttcttcctcg ctcatgccat caataatttt
    31981 ttctaccatg gccttgtgga agcgtttatg cagcctatga atcaagcgac ccttctttgt
    32041 caaatgcaga tgcaccacac gacgatcctg ttctgaccga actcgctcaa tgtagccctt
    32101 acgctctaaa ttgttcaaac ttgtcgtaac agttccaaga gttaccatca actcttttga
    32161 cacttgactt ggagtcacgt ctggagcctt accgatgaca tcaatcgtat gcatttcttt
    32221 gatggagata tccttaaaac gactacctct caagttcact tcctcaatta caaggacatt
    32281 gttaaatata gatgttaaat attcattgat tcgttggtag tccatttttc atatccctcc
    32341 ttcttcaaaa aacttttaca atcaaaacat ttgacagaaa gaattatatc aaaattcaaa
    32401 gaatgatgca agtatttttt attttcctgt aaatttaggt cttcttctct ccgaatgagc
    32461 tcgcactcct tctttgaaat cctctgtttg agctaaggat ttctgtaggt tcagttctaa
    32521 agtagcgtaa ccctgccagt ctttaaattg gctctcccaa accaacttct taatggcagc
    32581 ataggaatta cttgaagcac gtcttaattt tttaagaagc tgttctctcg tcttttcaag
    32641 tttttcagct tcagaaacgc gataaaccaa cccccattct agggcttttt ctgccgttaa
    32701 agcctctcct gtcatagcta attgagcagc acgcgtcaca ccgatactgc ggctcaagag
    32761 atgaattccc cctgcatctg gagccaaacc aacaccaaca aaggcttgga taaacttagc
    32821 cttatccgtc gccaaacaga aatctgccgc aacagccata ttcgctgcgg cacctgcaac
    32881 agcaccgtca acttccatta aaacaggttt ggctatttgc ttgattttat aagaaatcgt
    32941 attgaccaac tctgcgattt ttgtcaatga tggaatatca tcctcatcca ctgcccgctt
    33001 catctctacc aaatctcccc caactgagaa gacctttcca ttggcattga ttaagataaa
    33061 atgcacagct ggattttctt ctgccaaagt cagagcttct aaaatctcct cacacatggg
    33121 aatatgaaaa ccatttgcga cctcaggacg gttcaaggta aggattgcca agtcctcttc
    33181 aagctgataa ataatgtgtt ccatcagggc tcctttttat tttataagca gtttatactc
    33241 ttcgaaaatc tcttcaaacc gcgtcagctt ccatctgcaa cctcaaagca gtgctttgag
    33301 ctgacttcgg ctagcttcct agtttgctct ttgattttca ttgagtgtta aattatttca
    33361 ctgtcaaagt atatcttttt taggagcaga aagcaagaaa aaatcgactg aaagtgtctc
    33421 agccgataag aaaggctcgc tttaggctag aaagcatctt attttcttca ttgaaaaaag
    33481 cctttctttc tgctataatc gtataaaata cttactttag gagttcttat gaaagttgtt
    33541 aaatttggag gtagttctct tgcctctgct agtcaattag aaaaagtttt aaacatcgtc
    33601 aaaagcgatt cagagcgtcg ttttgtagtc gtttctgcgc ctggtaaacg caatgctgaa
    33661 gatactaagg ttacggatgc cctgattaaa tactaccgcg actatgttgc gggtaacgat
    33721 attagcaaga gccaaagctg gattatcgac cgctatgctg ctatggttag tgaattggga
    33781 ctaaaaccag ctgtgctaga aaaaatttct aaaagtattc acgccttggc cactcttcct
    33841 attgaagaaa atgaatttct ctacgatact ttcctagcag ccggtgaaaa taacaatgcc
    33901 aaattgattg ctgcctactt taaccaaaat ggtatcgatg cacgctatat gcaccctaga
    33961 gaagctggga ttgtggtcac aagtgaacct ggtcacgctc gcatcattcc atcaagttat
    34021 gacaagattg aagaattgac aaacaccaat gaagtccttg tcattcctgg tttctttggt
    34081 gtcactaagg aaaatcaaat ctgtactttc tcacgtggag gttctgatat tacaggttct
    34141 atcattgctg ctggtgtcaa agctgacctc tatgaaaact ttacggacgt tgatggtatc
    34201 tttgcagccc accctggtat tatccaccaa ccacactcga ttcctgagtt gacctaccgt
    34261 gaaatgcgcg agttggccta tgcaggcttc tcagtccttc atgacgaggc tcttcttcct
    34321 gcctaccgtg gaaaaattcc tctggttatc aagaatacca acaaccctga ccatccaggt
    34381 actcgtatcg ttctaaaaca cagtaatgat gaatttccag ttgtgggaat tgctggtgac
    34441 tcaggctttg tcagcattaa catgtcgaaa tacctcatga accgtgaggt tggatttggc
    34501 cgcaaggttc tgcaaatcct ggaagaactt aacatcggtt gggaacatat gccaacaggt
    34561 atcgacgatc tttctatcat tctccgttct cgccaactaa ctcccatcaa ggaagaagaa
    34621 atcctgcgtc agttggttca aaaggctaaa gtagatcatg cagaaatcga acacgacctt
    34681 tctatcatta tgattgttgg tgaaaaaatg aagagccaca tcggagtgac tgctactgcg
    34741 acacgcgctc tatctgaaaa caaaatcaac atccagatga tgtctcaagg ttctagtgaa
    34801 gtttctatta tgtttgttgt caataaagac caagagaaag cagcaattaa agccctctac
    34861 aatgcctttt ttggagaaag taaggaagac taagcatggc ccaatcactt aacaaaacag
    34921 tactcctcag tacgacaggc acttcctacc tctctatcgc tgggaaagtt gggaaattcc
    34981 ttgtcggaga tcaggctttg gaattttacc cagatgtcaa tgtcgaacaa tttatccaga
    35041 ttccttggag ccatatcaat cagattggag ccaatgtcac tggacgcaaa atcagccgcc
    35101 acttcgaagt ctttacagac aaaggaaaat tcctctttgc ttcaaaagac tcaggtgcca
    35161 ttctcaaaat tgcacgcaaa aaactaggca atgacaaggt cgtcaaactt ccgaccctga
    35221 ttcagacaat tagccaaaaa tttaaaaatc tatttgcaaa aaagtagaaa ctttagtata
    35281 atcatagcaa cggataagta ggttatcttc ttctttcaga aagtctgcgg gtactgcgag
    35341 cagataggag ggataggtga aattctaccg ttaataacaa ttacatacac aatcaagtgc
    35401 acacctgtga agttggatgg aaccgtggcc ctgccactcc aacgttttgt caggcgtgct
    35461 tttttcataa aggagttctt atgttagata tcaaacgtat tcgtacagat tttgaagctg
    35521 tcgcagaaaa attagctaca cgtggtgtag atgctgctgt cttgaatgaa atgaaagaaa
    35581 tcgatgctaa acgtcgtaac atcttggtca aggttgaaac tctcaaagca gaacgtaaca
    35641 cagtttctgc tgagattgcc caagctaagc gcaacaagga aaatacagat gacaagattg
    35701 ctgccatgca aaatctatct gctgaggtta aagccttgga tgctgaattg gcagaaatcg
    35761 atgctaaatt gacagaattt acaacgactc ttccaaatat cccagctgac agcgttcctg
    35821 ttgggactga cgaagacgac aatgtggaag ttcgccgttg gggtactcca cgcgagtttg
    35881 acttcgaacc taaagctcac tgggatctcg gtgaagacct tggtatcctt gactgggaac
    35941 gcggtggtaa ggtaacaggc gctcgcttcc tcttctataa aggcctcggt gctcgtttgg
    36001 aacgtgctat ctacaacttt atgttggatg aacatggaaa agaaggctat actgaagtca
    36061 tcacacctta catagtcaac catgattcta tgtttggtac tggtcagtat ccaaaattta
    36121 aggaagatac ttttgaactc agcgatacca actttgtctt gattccaact gctgaagttc
    36181 ctctgacaaa ctactaccgt gatgaaatct tagacggcaa agatcttcca atctacttca
    36241 ctgccatgag tccgtcattc cgttctgagg ctggttctgc cggtcgtgat acgcgtggct
    36301 tgatccgttt gcaccaattc cacaaggttg aaatggtcaa atttgccaaa ccagaagaat
    36361 cttacgaaga attggaaaaa atgacagcca acgctgaaaa cattcttcaa aaactcaacc
    36421 ttccataccg tgtcgttgct ctctctactg gagatatggg cttctcagct acgaagactt
    36481 acgacttgga agtgtggatt ccagcacaaa acaattaccg tgaaatctca agctgttcaa
    36541 acacagaaga tttccaagcc cgtcgtgccc aaatccgtta ccgtgatgaa gcagatggca
    36601 aggtgaaact ccttcatacc ttgaacggtt ctggacttgc agttggacgt acagtggctg
    36661 caattcttga aaattaccaa aatgaagatg gttctgtgac catcccagaa gcacttcgtc
    36721 catacatggg tggagctgaa gtcatcaaac cataaaaaat aaggtttagc tatttctagc
    36781 tagacctttt ttcgtaacca aatcagataa gcacccagta caaagaataa aatagttagg
    36841 catataatgg tttcagccaa taccaggtaa tccagaaatg gaagtttcaa aattccctga
    36901 gccatcttga gcgaggtcgc tgtgataatg gttgggaagg tgagggctga gaaggctggt
    36961 tgaaaacctt gttttaaaat gttgggcaga cgagttaaaa caaagaaaaa gaaggattga
    37021 gaagccaaaa taatgacaat caagacccaa gtcggcaggc tggttcctcc tactcgaact
    37081 agagaagcca agagtagaga gaaaggagca cagtagattc cttcttgtcc aagcaaggct
    37141 agtgggagtg gatgtttctt taaatcgcta taaataaggg gatagagata gaaggtcaag
    37201 agaaaaccaa aactcaaggt cgcataggca atttcgataa tacctaccag aggataggtc
    37261 aaggcagcca ctgctatccc cacatagaga accgtccaac ttggagtggc atgaaccctc
    37321 cgccctggac aagcaaactt gatggtaaaa ccagcaatca aggtcaaatc caagagaaat
    37381 gaaaaccacc aaatcccttg tgctaccaaa ggaagataag agaatacgcg aaagacatag
    37441 gtcgataaaa tcatcccagc cataggaaag gttgccattc ctgacaaaag agggggcttg
    37501 gtcaattctt gcttggtttc tttccaatta aagagatgca gaattagaaa gtaaatccat
    37561 aaaaccaaac cagtcagact aaaaagatgg gatagaaccg gcaacgtatc taaaataaga
    37621 tttccagctc ctgccaaacc tagcaaacaa cctgaaaata ctaaggggag ttttttcatc
    37681 ctaacctcca ataatcatgt tagtttcagt ataacataaa agcgcttaaa tgaggattta
    37741 aaaaaacgaa gtccgcttat ttcagacttc attttactca gatatgaatt aggcataagg
    37801 ttgcaattct ggattaattg gtgtattagc taagttgttg gcatagttac agaggattgc
    37861 taggctgaca ccaaaaacca catccaaggc attttgttga gtgtagccag cttctaaaaa
    37921 ctcagacaag gcttcatctc ctacacgacc cttggtattg ataactgcca aggtaaactt
    37981 agctagggta tccaatttag gatctgtttc aattggagta cgattgcgaa gagcttgaat
    38041 caagtcatca ttcatctgga tttgtttgat ggaaaaggct gtgtgacctg cgacacagaa
    38101 ggcacaacca ttggtcacgg ctgccgtgat ttgcaccact tcacgctcaa cgggtgtcag
    38161 gctgttgcga cggtggatag atgagacaat ttggtaggct tctaaaacag tcggggcatt
    38221 ggccaagaga ccgattaggt tgggaatata gccattgttg tctttttcta ctgtttcaag
    38281 aatttctttc acttctgctg gtgctgactc tactgtatgg atagtaaatg ttgtcataag
    38341 atacctcttt tcttattatt gacactaata ttattggaaa atcttataaa atcctgattc
    38401 ctaagtttat ctaagataaa gctttattct ctcataagat tttcgttgtt atattagttt
    38461 atcacacttc caatcacttg cataatatat attatatatc aggctgataa aaattattta
    38521 taggcaaaaa atcacacgag ctgtgtgatt ccattatttg tcaaaatact ttttagtttc
    38581 agcaataacg actggcgaca agaccaagag ggcaatcaag tttggcagag ccatcaaggc
    38641 gttaacgata tctgcgataa tccagaccat atccaactcg ataaatcctc ctaacaagac
    38701 catgagcaca aaaaccacac ggtagagcca gataaagcga gccccaaaga ggaactcaaa
    38761 acagcgttct ccgtaatagt tccaacctag aatcgttgta aaggcaaaaa gtacaaggaa
    38821 gatggtcaag agggcaggcc caaagtgtga aaagactgtt gagaaagctg actgagtcaa
    38881 ggcaacccca ttcaagtcac cactccaaac tccagttacc aagatggtca aaccagttag
    38941 agtacaaatg atgagggtat caataaaggt tcctgtcatg gaaatcaaac cttgctctac
    39001 tggttcattt gtcttggcag ctgcagctgc aataggagca gaacccagac cagattcgtt
    39061 tgagaacaca ccacgcgcca caccattttg aatagccatc cgaacgctag caccagcaaa
    39121 tccacctacc gcagcaaggg gactaaaagc tgaggtaaag actaaagcga ttgtgccagg
    39181 gatttttccg atattaaaga aaataactgt aagagttcct aagatataaa tgagggccat
    39241 aaaaggaaca acagtagttg aaaccttaga aatagacttg agtccaccaa agactgcaat
    39301 cgctacaaag acagacaaga cgagagctgt gatggctggc gaaatcgtcg ttgtattttg
    39361 gatagattct gcaatcgagt tgacttgggt gaaggttccg attcccaaga gaacaaccaa
    39421 tactcctgct actgcaaaca aaacagcaag tggtcgccac ttttctccca tccctagaag
    39481 gatatagtgc atgggacctc ccgctactgc accatggtcg tccttggtgc ggtatttgat
    39541 ggccaagagt ccttccgcat acttggtagc cattccaaag aaagccgcca tccacatcca
    39601 aaatagagct cctggtccac caaccttgat agccgtcgca actcctatga tatttcctgt
    39661 tccaacagtt gatgccaagg ctgtacacag agctgcaaaa ctggatacat caccatgtcc
    39721 cttatcctgg ataaaaataa gctgaaaggc cttgggcaga cgcaaaacct gcaagagtcc
    39781 tagccgcatg gttaggtaaa tccctgttcc gaccaataaa atcaagaggg gcggtcccca
    39841 agcaaaagca tcgattgatt taagcaattc taacatttcc ttctcctatc gtttcaaccc
    39901 caaaagaaag agcacatgca agatacatgt actctggaat gcttagataa atgctaaaaa
    39961 gcggtctatc ctagctctgt ccttttacct gagagtttga gcagttgcct gccttgcccc
    40021 ttcggtgcct ttacggtctc tccagagttc cgtccattta cagtcatgga aaatcaaacg
    40081 attccccact tctattaaac ttcattcggt gttggtattt aattgattct tattttacaa
    40141 aaaatgttgg cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag tttttacttt
    40201 ataaagtcca gaatactgct atcctttaaa agtgacaata gtcgcaccac tgcctccagc
    40261 attttgtggg gcatagccga aactcttgac atgtttgttt ctttgcaagt atttggtaac
    40321 tccttcacgg atgactcctg ttccgatacc atggatgata tcaacttgag ccatattgtt
    40381 aagcaaggct tggtcgatga aggtatctag ctcattcatg gcttcttcat agcgcttgcc
    40441 tcgaagatcc agtctagctt gaggtcctcg cccagaagtt cgtttcacaa cattgacctg
    40501 tttcttcttg actggttttt cttgctgggc ttgaacaaga tcaaactctt tctcttccaa
    40561 ggtcatctta atcaagccaa cttgggcttc ccagcgaccg tccttgagtt gactggtcaa
    40621 ggtaccacgc tgaccataac tgagaaccac gatatcatct cccacctttg gagctcgttt
    40681 tttcttggcc ttttgaagga ccttattttt agacaagtcc actttttcag gagccaattt
    40741 tttcaacttg gccttggctt caatgatttc gtggggcttg agttgggatt tactgtggag
    40801 atttttgaga atctggtcac tttcacttag ggccatatcc acaatctcag cagcctgttc
    40861 acgcgccttg ttaagctcgg tttccttttc acgattaagc tcgttgtaga gtttttttag
    40921 cgcacggttc atcttgagat tttcttgctc cacctcacgg atattgtcca aacgtttgcg
    40981 gctttccagc gtctgctctt ctaattgctc aatgatacga ttgacgtcat tgtcctgatc
    41041 gatctgctga ctggcatctc ctacgataac ttcagatagg cctagacgtt tggcaatttc
    41101 aaaggcatta cttcggccag gaacaccctg cataaagcga taggtcgggc gaagagttgc
    41161 agtatcaaac tccatactgg cattttgcac aaaggctgtc tcaataccgt aggccttgag
    41221 ttctggatag tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt cctccagaat
    41281 agccatggca agggctgctc cctcttgggg atcagtacca gcccccaact catccaaaag
    41341 taagagtgaa tgttggttga ccttgccaag aatatccacg atattggtca tatggctaga
    41401 gaaggtagac aagctctgct caatagactg ctcatctcca atatcagcaa agatttcttc
    41461 aaaaatacca acacgacttc ccttgtctgc taaaatcggc aatcctgact gggccatgac
    41521 ctgtgtcaag cccagagttt tgagcatgat ggtcttccca cctgtattgg gacctgtaat
    41581 gacaatagct gttaaatctt gaccaaaatg gacatcattt gcgacggcat ttttgaccaa
    41641 aggatggcag acatggagca gttgaatctc ttgattttct gacagctgag gcacgactgc
    41701 ttgtctttct tggataaatc gaaccttggc acgaatcaag tccagatgac cgataatcca
    41761 agcgtcatta gcaatctcag ccgcatgagg gcggacacgc tcagaaattt cttggagaat
    41821 gcgaagcatt tcatagcgct catctgctcg cagactagca atttcttcgc tcagtttgac
    41881 tacctcacgt ggttcgatat agacggtgtt tccactagca gaaatatcat gaacgacacc
    41941 tgcaatctta ttgcggtagg tgtttttgac tggtaaaacc tgacggccat ttctgctagc
    42001 aacaattcct tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta aaacatcgcg
    42061 tacctgactc tcgctatcat gtatttttcg acggattcgc gccaattctt cactggcaaa
    42121 attttcaatg aaacccgcat cattaaaggc ctgaagattt ccttgtaatt gcggaaaatc
    42181 atgtaatttc tcaaaccaaa gggctaattc ttccaagctg acattttcca gattggtgta
    42241 aaaattttga agttctcggc tggcaagaag cacgcgtttc aagagtagga actcctcgat
    42301 attgagatcc gctcccatct ccaacctctt gcagactcct gcaatttcct tagttgagag
    42361 aatagtaaaa tgcggttgct cgacgaaaag agcctgcatt tccttcatct cagcaaaagc
    42421 ctgtttgatt ttatctgctt tggcagtcgg agccagttgt ctcaattgct ccaagccctg
    42481 ctcggtcaac aaatgaggct caaacaaggc cttgacctta tcgaactcta atgtttctaa
    42541 tattttctta ttcatcttta tttccttgtc tttgaatgtc taggtgtggt agctttttac
    42601 attctgatag attcgagtca aatctgtaaa caaagggcta ggaaaactcc tgcccttttt
    42661 atccgattaa atttgtcacc cagatttgtt tgagccaact ggttgttatc ggtatgctct
    42721 ggatgatgtg ttttgcgacg atactctttt caagaggatt ttgtataact gccatgggga
    42781 tggtcgccaa gattgtcaag gccatttgca agacaaataa ggtcaccaac atggacaaga
    42841 tacctgctga aacttggaac aacttaccac ccagtttttt gctaggaatc aagtgtaaga
    42901 gaagaccaag caaacgacca atgctataga caatcccaaa tacaagcaag tagccgatac
    42961 ctgcataaaa gaccttatcc agctgaaaga gttgatccga tgggaaaaag aaagtcccct
    43021 gaccttcctg cgaatttgca taagggagca ataaatggaa ttgctctcca agccccttat
    43081 aaaactggcc agccataaaa gccgatgcca tggctgaaat caggtaataa acctgtaaga
    43141 gcaggcctct ccgatagccg atataaaatc cccaaaccaa gaccaataga agaaggaatg
    43201 aaatcataag gaatcctcaa tcttgctctg ttcttgctta caagtcacaa gcttgtgacg
    43261 gagttcttct agctcttgct ccttatcgtc aaattcaatc tcacggctga gctgagttga
    43321 taaacagttg actgccaaca aaagagcgat tgtttcatca tctgcgctag gcatttgttc
    43381 tttaattgct tggtattttt ctgtcgcaac cttagcgatt tcctccataa aaaggttatc
    43441 atgttcgctt gtcaaggtta acgatttttt cccgaatgta aatttgaatc gatttagatt
    43501 tgccataaaa ttcacctcac gatattatac caaaattcgc taattttgtc agtttttaca
    43561 aattttactg cttttgtggt acaatagaaa ctatggcaag tatcacactc acaccaagcg
    43621 aaaaggatat tcaggctttt cttgaacact atcaaaccag tctggctccc agtaagaatc
    43681 cctatatccg ctactttttg aaactacctc aagcaacggt ttctatctat acttctggaa
    43741 aaatcttgct tcagggtgaa ggggctgaga aatacgctag tttctttggc tatcaagctg
    43801 tagagcaaac cagcggacaa aatcttcctt taattgggac agatgaggtg ggaaatggtt
    43861 cctactttgg tgggcttgca gttgtggctg cctttgtcac atctgaccag cacgactttt
    43921 tacgaaaact cggtgtgggg gattctaaga ctctgaccga ccaaaagatc cgtcagattg
    43981 ctcctattct caaggaaaaa atccagcacc aggcactcct tctctcaccc agcaagtaca
    44041 acgaggtcat cggagaccgc tacaatgctg tttcggttaa ggttgccctc cataatcagg
    44101 ctatctatct cctccttcaa aaaggtgttc agcctgagaa aattgtgatt gatgccttta
    44161 ccagtgctaa aaattatgac aagtacttgg cacaagaggc caatcgtttc agcaatccta
    44221 tcagcttaga agaaaaggct gagggcaaat acttgtctgt cgcagtttct tctgtcattg
    44281 cgcgtgatct ctttctggaa aatcttgaaa atttgggacg agaactgggt tatcagctcc
    44341 caagtggagc tggaacggct tctgacaagg tggctagcca gattttgcaa gcctatggta
    44401 tgcagggact cagcttctgc gccaaattgc actttaaaaa cactgaaaaa gcgaaaaaac
    44461 gcttagaaag gtaagttatg aattcattta aaaatttctt aaaagagtgg ggattgttcc
    44521 tcctaattct gtcattacta gctttaagtc gtatcttttt ttggagcaat gttcgcgtag
    44581 aaggacattc catggatccg accctagcgg atggcgaaat tctcttcgtt gtaaaacacc
    44641 ttcctattga ccgttttgat atcgtggtgg cccatgagga agatggcaat aaggacatcg
    44701 tcaagcgcgt gattggaatg cctggcgaca ccattcgtta cgaaaatgat aaactctaca
    44761 tcaatgacaa agaaacggac gagccttatc tagcagacta tatcaaacgc ttcaaggatg
    44821 acaaactcca aagcacttac tcaggcaagg gctttgaagg aaataaagga actttcttta
    44881 gaagtatcgc tcaaaaagcc caagccttca cagttgatgt caactacaac accaacttta
    44941 gctttactgt tccagaagga gaataccttc tcctcggaga tgaccgcttg gtttcgagcg
    45001 acagccgcca cgtaggtacc ttcaaagcaa aagatatcac aggggaagct aaattccgct
    45061 tctggccaat cacccgtatc ggaacatttt aagaaaccta agaggccgag aatcaccaat
    45121 ctcagcctct tcttctatcg tgagaaaatg attggtaact atctaaactt accagaacag
    45181 aaacacctca actctcacct attcatgcaa aggaatttta tggaagttta tttttcagga
    45241 accattgaac ggattatttt tgaaaatccc agcaattttt atcgcatcct cctcctagaa
    45301 atcgacgata cggacgcaga ggattttgat gactttgaaa tcattgtcac aggaaccatg
    45361 gctgatgtaa ttgagggcga agactatact ttttgggggc aaattgtcca gcactccaag
    45421 tatggagaac aactgcaaat cagtcgttat gatcgcgcaa aaccaactag taagggcttg
    45481 gtcaagtact tttcaagtag ccatttcaag gggattggtc tcaagacagc tcagaaaatc
    45541 gtggatacct atggcgaaaa taccattgac gaaattttgc aacacccaga aaagttagaa
    45601 ggcatcgcag gactctctgc caaaaatcgc gaggctttcg tctccactct ccgtctcaac
    45661 tacggaacgg agatggtttt ggccaaacta gccaactacg gcattcccaa caaactagcc
    45721 tttcagattc aagactttta caaggaagaa acccttgatg tggttgaaaa ttatccctac
    45781 cagctggttg aggatatcaa gggtttgggc tttaccattg ctgaccaact agctgaggaa
    45841 ctaggcatcg aaagtcaggc tcctgaacgc ttccgcgccg gtctagttca cagtcttttt
    45901 caggcctgta tggaaacagg ggacacctat gttgaagcac gggatttgct ggaacaaacc
    45961 cttactctcc ttgagtcttc ccgtcccgtg gaactagacc ccagccaagt tgcccaagag
    46021 ctctcctacc tgatcgaaga agacaaggtt cagcagattg ataccaagat ctttgacaac
    46081 agcctctttt tcgctgagga aggcatccgc agtcacttgg ttcgtatcct tgaaaaagga
    46141 aaacagaaga gtcatgattt aaaaaccatt caaaaacata tcactactat cgagcaagag
    46201 cttggaattg agtatgataa cattcaaaaa caggctatct gtgatgctat ccagaataag
    46261 gtctttatcc tgacaggtgg acctggtact ggtaagacaa ctgttatcaa tgggatcatc
    46321 gctgtttacg ccctgttaga gggacttgac ttcaggaaga aaagcaacct gcccattctt
    46381 cttgctgctc caactggtcg agctgctcgt cgcatgaatg aattgacagg tttgcctagc
    46441 gcgaccatac accgccactt gggaatgaca ggtgacgatg ataccagtca tctggaagat
    46501 tacctagatg ctgactttat catcgtggat gaattctcta tggtggatac ttggctggcc
    46561 aatcaactct tctccaatat ctcttctaac agtaagatcc tcatcgtagg tgacagtgat
    46621 cagctacctt ctgtcagtcc tggacaggtt ctagcggatc tgcttcatat tcctttgatt
    46681 cctcagactc gcttggaaaa aatttatcga caaagcgaag aatcaaccat cgtcacccta
    46741 gctagtcaga ttcgacaggg catcttgcca gctgatttca cccaaaaaaa agctgaccgt
    46801 tcctactttg aaattgctag tggccatatt cctgccacca ttgaaaaaat cttaggtgcc
    46861 gccctcagaa atggtattcc tgcccgtgat atccaagttc tggctcctat gtaccgaggg
    46921 acggcaggga ttgatgctat caatcagctc atgcaagacc tgctcaatcc cccacaaaaa
    46981 gatcaactca gttttgaagc tcctcagtgc cactatcgta agggagacaa ggtcattcat
    47041 ttggttaacg atgctgaaat caatgtcttt aatggggatt taggagctat cacagacctg
    47101 attcctggta aatacaccga atcgaaacaa gacgagattg tcattgattt tgatggtaat
    47161 gaagtctctt acccccgtaa cgaatggtac aagattcgct tggcctatgc catgagtatt
    47221 cataagtctc agggaagtga gttcccagtt gtcatcctac cgattactag tgctagccga
    47281 cgtatgctgg agcgaaatct catctacaca gccattacac gtgccaaaag caaactcatc
    47341 ttactaggcg aattacaagc cttcgactat gctacccaac acatcggaac tgcccgaaaa
    47401 acctatctga ttgaacgctt cagtgatcta ctggagaatg ttgaagaaaa gcaacaagct
    47461 gtctctgaaa cagtcacatc aagtgcctct gaacaatcct acatcctaac cgaagaaaac
    47521 tgggacagca ttccagccat gattgggatt acagacacag acctcaaaga gatttttgga
    47581 aaatagtaca tcagaaaacc caccaattca ggtgggtttt ctgtttatta agattatttt
    47641 actgttgctg tgcttgtgat caattcaaca gcttttttga tagtgatatc atgtttcaac
    47701 atgtcagctg aaagcaagtt ttgaacttgt gcaacttcca tgttgtagtc tgctgccaat
    47761 tgctcaactt ctttttggat ttcttcttct gaagcatcaa atccttcagc tttggcaact
    47821 gcttcgataa caaggttagt cttagtacgt gactcagctt ctgcttggta ttggttgtga
    47881 aggtcttctt gagtagttcc agtgatttgg aagtacatgt cagggttgat cccttgacgt
    47941 tgcaagttcc caaggaattc atttactgaa cggtgaactt cttcatggat catttcttct
    48001 ggaagttcta cgatttcagc gttttctaca gctgtatcaa ttgctgcacc ttcaactgca
    48061 tctttgtaag cttcttcttt agcagcagcc aattctttgc ggtatttttc tttcaagtca
    48121 gcaagtgttt caacttcttc atcaatgtct tttgcaagtt catcgtcaag agctggaact
    48181 tctttagctt ttacttcgtg gatagttgtc acgaatttag cttctttacc tgcaaggtct
    48241 tctgcttggt agtcttctgg gaatgttacg ataacatcaa cggtttcgcc agctgagtga
    48301 cctaccaatt ggtcttcgaa accagggatg aattgacctg aaccaagtcc aagtgagaag
    48361 ttttcacctt ttccaccgtc aaattcaaca ccgtcgatag aaccaacgaa gtcgatcaca
    48421 acagtgtcgc cgttttcagc agcagcttcc ttgataacca attcagccag attgttgcgt
    48481 tcgcgttcga tacgctcttc aacatcagcg tcagttactt ctttttctac atcaactgat
    48541 acttcaaggt ttttgtagtc acccaatttt acttcaggtt ttgtaacgac ttcagcagcg
    48601 ataacccagt cttgaccttt ttccattgaa gttacgtcaa tttttggttg ggcaaccact
    48661 tcaagaccag cttcttttac agctgcttca taagcgtttg gcaaaagagc gttcataacg
    48721 tcttggtaaa gtgattcttc accaaatttt ttatcgaaga taggacgtgg aaggtgacct
    48781 ttacggaaac ctggaacatt aagagatttc ttcactgact tgaagacacg gtccaattct
    48841 ggtttgattt ggtcttgaga gatagtgaaa gtcaagacac cacggtttgt ttctttgttt
    48901 tcaaatgata cagacattct gtcatttctc cttaaaattt tttaaataca gtctattata
    48961 acattttcta taaataaaat ctagactaat gcagacaatt atagacaaca agcctttttc
    49021 ctaactaaaa cactcataaa gtatagacaa ttttagacta ctttggatat cttttggtta
    49081 gtcattttcc aaaactaatt tatctaattt ttaagttata tttgacttca tcttctcagt
    49141 aacatgagta taaacactta aaatctttgt ttcattagta taatctacac gatccattat
    49201 cgctattata ggtacttcca attcagcaag caaacttata tgcgaatatc taaaaacatg
    49261 agcagtcaat acaaaatcat ctttcttaat ttcacttttc ctaaacctgt ttttcaaaaa
    49321 gtaattgaaa caagttatca ttaagggaga accattattt gtaaatatat aatcaccttc
    49381 ttctaaaaga agatattctt ttaaaatttc taacactcta tcactaatac caattactct
    49441 atatgaagct aaacttttcg gactatccaa aaacacttcg ttattggacg attacattat
    49501 agtaaaacga aataagaaca ggacaaatcg atcaggacag tcaaatcaat ttctaacaat
    49561 gttttagaag tagaggtgta ctattatagt ttcaatctac tatacaagac gaaattgaag
    49621 aaatctttcc attataaaac gcatattatc aaggttttta aacacctaat aatatgcgtt
    49681 ttttcctatt ttaaagactt ttatccacct attatacaaa gttaagtatc catcacagtt
    49741 tacaattagc cttcattacc taacccattc accatccttc aagagagtaa cctttaagaa
    49801 ccgaataaat aaatgacaaa tttcgttcat ttaatttaac tgcactgtta atttgattag
    49861 ctccatctcc taaagtatgc actcctacta cacggtgact agcatcataa actgtagatc
    49921 cactagaccc ctctaaagta tcaacttggt aatccaagaa catgccatca tcacttaaaa
    49981 cttgtttttt atctgtatac atttgatgaa ttttaaaatt atatgatgga tagcctgtga
    50041 tagtcacagt tattcctgtc aaattttttt gactagtagg aaaacccaaa gtccctaatt
    50101 ttgcaccaat gggctcttct agaattaata aagccaagtc atattccctt tcatccttag
    50161 aatttaaatt tctaaattcc ttcaaataac aaacttcctt tactttgatc tttccaaata
    50221 gttcttgact tggactaaca gccggaagaa cataaatatc atccgcttct ttcccatagt
    50281 catgtctgta gtagttgtga gccgctgtaa ttaacacatt atctttaata aaattcgcac
    50341 ttcccctccc ttctacattc attccatcgg ctactccata atacttagat aaaaccatag
    50401 ctgaagtcga atacggatac tgtaaagtat tatcaatttt aatcaaatca tcattaccga
    50461 taatacttct gattgctttt ggtagtatga accatacgtt ggtgaaatct cagataatga
    50521 agaatcatta gaccctggac ctttttctag tgtctcactt acctcatatt cttcacctgt
    50581 actagaaata acactcaaag cagatactgt cgataactgg ctagccaata aagtactcgc
    50641 aataattgaa atacccaatt ttttataaac agttttcttc attattgtat cctcctaatg
    50701 taattatagc gtactattct aaatttctta atctactata gaatcaagaa atctaccacc
    50761 ttctttaaat accctccatt atcacataaa caggtaaact tttcaattaa tgactgcgct
    50821 tttcaatcac gctagaggta cttacttgct tctttgatac taagttcagc cattctttcc
    50881 ttgtttttct caataaagca tgttacccaa gtgggattcg ttttggagta gtctcgcaga
    50941 gtccagccaa tggctttatt gataaaaaat tctgtttggt tcaagttatg aagtagaatc
    51001 ttttccatta attgagtatt ggtcttctct tttcttaaca actggtggtc aatagcgaca
    51061 cgtctcagcc agatattatc tgataggctc cattttatac tcaatgaaaa tcaaagagca
    51121 aactaggaag ctagccgcag attgctcaaa acactgtttt gaggttgcag atagagctga
    51181 cgtggtttga agagattttc gaagagtatt aagattattt cttctagttc agggtgttca
    51241 tacaccaaac tccctactac tcgatctagg atatctaccg tgtcccacca ggattttgtc
    51301 acgactaact gctctagctt aggcaaatcg gtttccttta gataagactg cattgttttc
    51361 aaatagttag cagccacata ttggtatttt ctaggctcct tttcccagca agtgtctgca
    51421 aaatcccaat cgataatctt tgtttttttc gcttctagta aatattttta tagagtttat
    51481 ttctttcagg caccgcaata cctagaaaag aaaattgatg gcgcatatag gcttccatgg
    51541 accttgcttt tttagagtct tttgctgctt ctagctcctc aagtaaatct gctaaactca
    51601 tctaaaactc atcttgcccc accaaatggt gctgaaaggc atagacagcc gcctgggtac
    51661 gatcgctgac ttcaagtttg gcaagaatgt tggacacgtg ggtcttgacc gtcttgagag
    51721 agataaagag gtcatctgcg atgcgctgat tttcgtagcc cttggcgatg agttggagaa
    51781 catctcgctc acgcgcagtc aattcttcat gaagttccat atgattgcgg tggtattcaa
    51841 ccttcttgct aacctcttgc tcaatggcca gctcgccagc agctacctta ctgacggcat
    51901 gaagcaattc atctgcacta gaagtcttga gcatatagcc tttggcacca gcatctaaga
    51961 ctggcatgat tttttcattg tccaaataag aggtcacaat caaaatcttg gcttcaggcc
    52021 attctttaag gattgctaag gtcgcgtcaa tcccattcat ctcaggcatg acaatatcca
    52081 tgacaatgac atctggacgc agttccaagg ccaagtcaat cccttgagac ccgttggacg
    52141 cctcacccac aacttctaca tcgtcttgga ggtcaaagta gcttttcaaa cccaaacgga
    52201 ccatttcatg gtcatctact agtaaaattt tcatctttac tcctt
//
LOCUS       DBEJZV010000014        52025 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.14, whole genome shotgun sequence.
ACCESSION   DBEJZV010000014 DBEJZV010000000
VERSION     DBEJZV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 52025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52025
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.14"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            164..1927
                     /gene="aspS"
                     /locus_tag="ACL3S0_000996"
     CDS             164..1927
                     /gene="aspS"
                     /locus_tag="ACL3S0_000996"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGR1311930.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITESLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVRGVDFKVFSEAPAVKAIVVTGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1905..2846
                     /locus_tag="ACL3S0_000997"
     CDS             1905..2846
                     /locus_tag="ACL3S0_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR1311931.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLTFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(2882..3130)
                     /locus_tag="ACL3S0_000998"
     CDS             complement(2882..3130)
                     /locus_tag="ACL3S0_000998"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311932.1"
                     /translation="MKIKVQTRKLATGCSKHCFEVVDRTDEVSSKHGFEVVDETDGVS
                     SKHGFEVVDETDEVSSKHGFEVADRTDEVSNIHTVRRR"
     gene            complement(3272..4258)
                     /locus_tag="ACL3S0_000999"
     CDS             complement(3272..4258)
                     /locus_tag="ACL3S0_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1311933.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4268..5068)
                     /locus_tag="ACL3S0_001000"
     CDS             complement(4268..5068)
                     /locus_tag="ACL3S0_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGR1311934.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5329..6171)
                     /locus_tag="ACL3S0_001001"
     CDS             complement(5329..6171)
                     /locus_tag="ACL3S0_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGR1311935.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6173..7465)
                     /locus_tag="ACL3S0_001002"
     CDS             complement(6173..7465)
                     /locus_tag="ACL3S0_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGR1311936.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7576..8847)
                     /locus_tag="ACL3S0_001003"
     CDS             complement(7576..8847)
                     /locus_tag="ACL3S0_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR1311937.1"
                     /translation="MSSKFMKSAAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9382..10914
                     /gene="malQ"
                     /locus_tag="ACL3S0_001004"
                     /pseudo
     CDS             9382..10914
                     /gene="malQ"
                     /locus_tag="ACL3S0_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            10940..13198
                     /gene="glgP"
                     /locus_tag="ACL3S0_001005"
     CDS             10940..13198
                     /gene="glgP"
                     /locus_tag="ACL3S0_001005"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGR1311938.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGDENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14243..14815)
                     /locus_tag="ACL3S0_001006"
     CDS             complement(14243..14815)
                     /locus_tag="ACL3S0_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311939.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNRRINF"
     gene            14892..15098
                     /locus_tag="ACL3S0_001007"
     CDS             14892..15098
                     /locus_tag="ACL3S0_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311940.1"
                     /translation="MLKKYFSKYKWTDLFWILFVILTCLYIGNHDLFTLNHQEFSFRG
                     SVWGLVLALYHLLFIDKFVISNRK"
     gene            complement(15659..16507)
                     /locus_tag="ACL3S0_001008"
     CDS             complement(15659..16507)
                     /locus_tag="ACL3S0_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGR1311941.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNHHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAS
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            16659..16937
                     /locus_tag="ACL3S0_001009"
     CDS             16659..16937
                     /locus_tag="ACL3S0_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGR1311942.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            16939..19002
                     /locus_tag="ACL3S0_001010"
     CDS             16939..19002
                     /locus_tag="ACL3S0_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR1311943.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(19080..20336)
                     /gene="tyrS"
                     /locus_tag="ACL3S0_001011"
     CDS             complement(19080..20336)
                     /gene="tyrS"
                     /locus_tag="ACL3S0_001011"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGR1311944.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADTVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            20478..22940
                     /gene="pbp1b"
                     /locus_tag="ACL3S0_001012"
     CDS             20478..22940
                     /gene="pbp1b"
                     /locus_tag="ACL3S0_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGR1311945.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSRARR"
     gene            23005..23916
                     /locus_tag="ACL3S0_001013"
     CDS             23005..23916
                     /locus_tag="ACL3S0_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR1311946.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            24146..24844
                     /gene="dapD"
                     /locus_tag="ACL3S0_001014"
     CDS             24146..24844
                     /gene="dapD"
                     /locus_tag="ACL3S0_001014"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGR1311947.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            24912..26042
                     /locus_tag="ACL3S0_001015"
     CDS             24912..26042
                     /locus_tag="ACL3S0_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGR1311948.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            26054..26593
                     /locus_tag="ACL3S0_001016"
     CDS             26054..26593
                     /locus_tag="ACL3S0_001016"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGR1311949.1"
                     /translation="MKSELRKQVLQGMKAISQEQKQFIDQTLTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDLQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            26577..27254
                     /locus_tag="ACL3S0_001017"
     CDS             26577..27254
                     /locus_tag="ACL3S0_001017"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGR1311950.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(27321..28220)
                     /gene="galU"
                     /locus_tag="ACL3S0_001018"
     CDS             complement(27321..28220)
                     /gene="galU"
                     /locus_tag="ACL3S0_001018"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGR1311951.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKTVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(28242..29258)
                     /locus_tag="ACL3S0_001019"
     CDS             complement(28242..29258)
                     /locus_tag="ACL3S0_001019"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR1311952.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            29470..29910
                     /locus_tag="ACL3S0_001020"
     CDS             29470..29910
                     /locus_tag="ACL3S0_001020"
                     /inference="COORDINATES: protein motif:HMM:NF037495.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311953.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     ILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFAK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(30025..30456)
                     /locus_tag="ACL3S0_001021"
                     /pseudo
     CDS             complement(30025..30456)
                     /locus_tag="ACL3S0_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(30518..31168)
                     /gene="phoU"
                     /locus_tag="ACL3S0_001022"
     CDS             complement(30518..31168)
                     /gene="phoU"
                     /locus_tag="ACL3S0_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR1311954.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(31183..31935)
                     /gene="pstB"
                     /locus_tag="ACL3S0_001023"
     CDS             complement(31183..31935)
                     /gene="pstB"
                     /locus_tag="ACL3S0_001023"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR1311955.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(31937..32752)
                     /gene="pstA"
                     /locus_tag="ACL3S0_001024"
     CDS             complement(31937..32752)
                     /gene="pstA"
                     /locus_tag="ACL3S0_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR1311956.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(32745..33608)
                     /gene="pstC"
                     /locus_tag="ACL3S0_001025"
     CDS             complement(32745..33608)
                     /gene="pstC"
                     /locus_tag="ACL3S0_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR1311957.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(33726..34601)
                     /locus_tag="ACL3S0_001026"
     CDS             complement(33726..34601)
                     /locus_tag="ACL3S0_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGR1311958.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTTKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(34768..36099)
                     /gene="pnpS"
                     /locus_tag="ACL3S0_001027"
     CDS             complement(34768..36099)
                     /gene="pnpS"
                     /locus_tag="ACL3S0_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGR1311959.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(36100..36807)
                     /locus_tag="ACL3S0_001028"
     CDS             complement(36100..36807)
                     /locus_tag="ACL3S0_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1311960.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(36891..37377)
                     /locus_tag="ACL3S0_001029"
                     /pseudo
     CDS             complement(36891..37377)
                     /locus_tag="ACL3S0_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            37363..37920
                     /locus_tag="ACL3S0_001030"
                     /pseudo
     CDS             37363..37920
                     /locus_tag="ACL3S0_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(38235..39926)
                     /gene="argS"
                     /locus_tag="ACL3S0_001031"
     CDS             complement(38235..39926)
                     /gene="argS"
                     /locus_tag="ACL3S0_001031"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGR1311961.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            40062..40508
                     /gene="argR"
                     /locus_tag="ACL3S0_001032"
     CDS             40062..40508
                     /gene="argR"
                     /locus_tag="ACL3S0_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR1311962.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            40559..43093
                     /gene="mutS"
                     /locus_tag="ACL3S0_001033"
     CDS             40559..43093
                     /gene="mutS"
                     /locus_tag="ACL3S0_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGR1311963.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMENPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            43240..44934
                     /gene="patA"
                     /locus_tag="ACL3S0_001034"
     CDS             43240..44934
                     /gene="patA"
                     /locus_tag="ACL3S0_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGR1311964.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(45084..45527)
                     /locus_tag="ACL3S0_001035"
                     /pseudo
     CDS             complement(45084..45527)
                     /locus_tag="ACL3S0_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            45725..47491
                     /gene="patB"
                     /locus_tag="ACL3S0_001036"
     CDS             45725..47491
                     /gene="patB"
                     /locus_tag="ACL3S0_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGR1311965.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            47630..48319
                     /locus_tag="ACL3S0_001037"
     CDS             47630..48319
                     /locus_tag="ACL3S0_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR1311966.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            48323..48502
                     /locus_tag="ACL3S0_001038"
     CDS             48323..48502
                     /locus_tag="ACL3S0_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311967.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            48489..49838
                     /locus_tag="ACL3S0_001039"
     CDS             48489..49838
                     /locus_tag="ACL3S0_001039"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGR1311968.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            49962..51422
                     /gene="gltX"
                     /locus_tag="ACL3S0_001040"
     CDS             49962..51422
                     /gene="gltX"
                     /locus_tag="ACL3S0_001040"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGR1311969.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESYENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            51436..51870
                     /locus_tag="ACL3S0_001041"
     CDS             51436..51870
                     /locus_tag="ACL3S0_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR1311970.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVSELIPYWWGEERASKFNER"
BASE COUNT        15280 a         9917 c        11349 g        15479 t
ORIGIN      
        1 aaggcgacgc tgacgtggct tgaagagatt ttcgaagagt attagcgcta atttttaggg
       61 ctttcacctg acttttaaag actggcaaac ttttctgatg attttcatga agagcctgcg
      121 cttttatggt aaaatagtaa cagaataaaa gaggagagaa ataatgaaac gtagtatgta
      181 tgctggtcgt gttcgtgagg aacacatcgg acaagaaata accttgaaag gatgggttgg
      241 ccgtcgtcgt gaccttggtg gtttgatctt tatcgatctt cgtgaccgtg aaggaatcat
      301 gcagttggtt atcaaccctg aaaaagtatc tgcagaggtt atggcaacag ctgaaagcct
      361 tcgtagcgaa tttgttattg aggtgactgg tcaggtcgct gcgcgtgagc aagccaatga
      421 taagttgcca actggtgcgg ttgagttaaa cgtgacagct cttattgtgc ttaacacagc
      481 taagacaaca ccatttgaga ttaaggatgg cattgaggca aatgacgata cacgtttgcg
      541 ttaccgttac cttgaccttc gtcgtccaga aatgttggaa aatcttaaac ttcgtgccaa
      601 ggtgacccac tctatccgca actacttgga tgagttggag tttatcgacg tggagacacc
      661 attcctttct aagtcaacgc ctgaaggggc gcgtgattat ttagtgccgt ctcgtgttaa
      721 taaggggcat ttttacgctc ttcctcaaag tccacaaatc acgaaacagc tcttgatgaa
      781 tgctggtttt gaccgttact accaaatcgt taaatgtttc cgtgacgagg acttgcgtgg
      841 agaccgccag cctgaattta ctcaggtcga cttggaaacg tccttcctta ctgagcaaga
      901 aatccaagat attacagaaa gcttgatcgc gcgcgtgatg aaggaaacaa aaggcatcga
      961 agtaacgcta ccattccctc gtatgaaata cgatgatgct atggctcttt acggttctga
     1021 caagccagat actcgttttg acatgttgct tcaggacttg acagaagtgg tccgaggtgt
     1081 agactttaaa gtcttttcag aagcacctgc tgtaaaagcg attgtggtca caggagctgc
     1141 ggacaactat tcacgtaaag acatcgacaa gatgacggaa gtagccaaac agtatggtgc
     1201 caaaggtctt gcttgggtca aggtggttga tggagaatta aacggaccag ttgccaagtt
     1261 cttgactggt atccaagaag aattgacaac agcgcttgtt cttgaagata aggacttggt
     1321 tctctttgtg gcggatacgc ttgaagtggc taatgcaaca ctgggtgccc ttcgtggacg
     1381 tattgctaaa gagcttggct tgattgataa tgataagttc aacttccttt gggtggttga
     1441 ctggccgatg tttgaatggt ctgaagaaga aggccgctac atgagcgccc accatccttt
     1501 cacacttcca caggaagaga ctgctcatga attagaaggt gatttggcta aggttcgtgc
     1561 cattgcttac gatatcgtct tgaacggtta tgagcttggt ggtggtagcc ttcgtatcaa
     1621 ccaaaaagac cttcaagaac gcatgttcaa ggctcttggt ttctcaactg aagaagccaa
     1681 tgaccagttt ggtttccttc ttgaagccat ggactatggt ttcccaccac acggtggttt
     1741 ggctatcggg cttgaccgtt ttgtcatgtt gcttgctgga gaagaaaata tccgtgaagt
     1801 cattgccttt cctaagaaca acaaggcaac tgacccaatg acacaagctc catcaacagt
     1861 cgctctcaaa caactagagg aactcagctt acaagtagaa gaagatgaaa caaacaaaac
     1921 gaattaagcg gtggcgctat tatctgcgcc gctttgctta tcagataaaa attttacgtg
     1981 tcttacaaag tatctctcga gaaaagtatg atgagaagat ttcggcctct ctggtctatg
     2041 gttttttatc agcagtagca gttaatttct ttttccaacc agggcatgtg tattcgagtg
     2101 gtgcaacagg tctggcacag attatctctg ccttgagtaa tcactggttt ggttttcata
     2161 ttccgatttc gctaaccttc tacgccatta acttcccttt gatggtctta gcttggtatc
     2221 agattggcca taagttcacc gtctttacct ttatcacggt atctatgagt tccttcttta
     2281 tccagtttgt ccctgtggca accttgacgg aggatcccat tatcaatgcc ctttttgggg
     2341 gtgttgttat gggtttgggg attggttttg ctcttcgaaa caatatctcc agtggtggga
     2401 cggatatcgt cagcctgact attcgcaaga aaacgggtaa gaatgttggt agtatttctt
     2461 tcttggtaaa tggaactatc atgctgatag caggtttgac ctttggttgg aaatacgctc
     2521 tttattctat gattaccatc tttgtctcta gccgtgtgac agacgcagtc tttactaagc
     2581 aaaagcgtat gcaggccatg attgtgacaa atcatccaga gaaggtaatt gaaaaaatcc
     2641 ataaaaaatt gcaccgcgga gcaaccatga tccatgatgc agaaggaacc tataatcacg
     2701 agagaaaggc agttttaatc actgtcatta cacgtgcaga gtttaatgaa tttaaacaga
     2761 ttatgacaca agtggatcca agctcctttg tctctgtctc ggaaaatgtt catattctag
     2821 gaagatttgt tgagatagat aattagtgat taatactctt cgaaaatctc ttcaaaccac
     2881 gtcagcgtcg ccttaccgta tgtatgttac tgacttcgtc agttctatct gcaacctcaa
     2941 aaccatgttt tgagctgact tcgtcagttt catctacaac ctcaaaacca tgttttgagc
     3001 tgactccgtc agtttcatct acaacctcaa aaccatgttt tgagctgact tcgtcagttc
     3061 tatccacaac ctcaaaacag tgttttgagc aacctgtggc tagcttccta gtttgcactt
     3121 tgattttcat tgagtataaa aagatcttgg gtaacaactc aatttcagta gaaaaggaag
     3181 taaatcttcc cacaataaaa cgcatagtat caagtttttt caatacctga tagtatgcgt
     3241 ttttgctttt aacgactttt tgcccagtct cttatttttc gataattttg tgggcgatca
     3301 attgacggta acaaatttgt ttattgtttt tattatcatt aataatctgg agaatagttt
     3361 caagggaaac acgaccaagc tctaaactat tgatatcgac ataggctgcc aagttgagct
     3421 tgggattaac cgagtcaaag ctgagaacag ggacatccag ctggtgtttg gcaatatagt
     3481 tacaaacacc ttcagctagg aggctatcgg ttgtgatgat agcatcaatt tgtggatcgt
     3541 gcttgaataa tcgcttgcta aatttatagc ccttttcttc cagaaactcg tcggcaaagt
     3601 agatgcgatt gttgtcagtg gtaagtttgt aatgtttaag cgcctgttca tagcctgtta
     3661 aacggtcttt ggtcacgaag agctttttac ttcctccgat aaaggcaatg cgtttgcagc
     3721 cttttttgat gaaatattca gtcgcatcaa aaccagcttg aacattgtcg ttgtcgacaa
     3781 gtgggatgaa aggagataga gatttaccta agataaggaa ggggaactgt tcttctgcga
     3841 cgagttttac gagagggtct tcttcttggg catagagaaa gattagccca tctacacgct
     3901 tgccgtagac catttgtgaa atagcgttga gacgctcctt ctcatctttc cctgttgcta
     3961 tctgaatggc atagtggttt tcagatgcga cttgagagat gccacgtaga accgatggaa
     4021 agaaaggatt ctggtagaag gcgtctgagt catcaggaag aactaatccg ataacctgag
     4081 tatagctgct taccaagcta cgagcgttga ggtttgggtg gtagttgagt tccttcatag
     4141 ctttgcgaac gcgttttttt gtttcgtcgc taatggttga tttattttga ataacacggg
     4201 ttacggttga aggcgaaaca ccagcagcct tggccacgtc tttaatcgta acgggcataa
     4261 aaatctccta tttatggtaa tttggatcac ggaaatgtgt tttataaaag atagtgacca
     4321 gatacagaac aaaaagaata ttttgtacag taatcagggt tgtcatattt tggccaaata
     4381 atcccaaaat aagtgtaatc agagtcggca atcctaaaca gttcaagata aagtgatagc
     4441 actctttaaa ggttctaaat gaaaagaggc gtgatttctt agtgatataa aggagaagac
     4501 tagctcctag agagacgata aagaaattca aaccaaagag gaagctcgca ccgagaacta
     4561 ggaagaggct gatatagaca cgattttgtt ggtaccagtc tttagaaatt gcttgggtca
     4621 agctgtcttt gcttttgaaa ctctcagtct gaatggctcg gtaagagatg cgggtcagtt
     4681 ccttgctttc cttgctgatg actagctcat ttgtatcgaa atgcagttgc aagtccttag
     4741 gtaattcctt gatttgactt ggaccaatca caacagaagg ggcttgacta gctgttccag
     4801 tataagttaa tgtgccatcg acaattgtag catgttcaga gagatcctgg acaacctcat
     4861 ttgtcagagg ttcatagaca ttatcgataa aagtttctag cggataggtc tcctgggagc
     4921 tgttttggat agcaatgggt accatagaca agctgataag gaagatactg gtaaagagaa
     4981 gttgaaacca gttgagctcg aaacgtttgg acaggggctt acgaaacccc caaatacttg
     5041 aaaaatagga aaatggatat ggaagcatag gtatctttct aaaaggtgtt ttctatatga
     5101 gtattattat atagagaaat gcgctttatt tcaagtctag ggggtaaatt gcttgctaca
     5161 aggatattat ttacagtgac aatcgctaat agtcaatgaa aatcaaagtg caaaccagga
     5221 agctagctgc aggttgctca aagcacaact ttgaggttgg agataaagct gacgtggctt
     5281 gaagagattt tcgaagagta taaaatgaaa aagggtggcg gggataaatt atcccttgtc
     5341 gccaccactt gtaagtcctg aaacaaagtt cttttgtagg aagaagaaga gaatacagat
     5401 tggaagggcg atgaggatag cacctgctga gaagtaggca atcttcaagt ttttcgcatt
     5461 gttaacgaag gtttggagac ctacggcaac agtaaagtat tctttctcac gaagcaagaa
     5521 actagagagg atgtagtccc cgaaaggtcc catgaaggcc cagagagctt gtacggcaac
     5581 cattgggcga acaagtggta gaacaatttg ccagaagcgg cggaagtgtc ctgcaccgtc
     5641 tagttttgca gattcgtcta aagacattgg cactgtatcg aagtagcctt tcatgagcca
     5701 agcattcatc gggataccac caccaacgta gaggaagatg aggaaccagt tgtggttaag
     5761 ggcgttcaac ataagcgcca taacgaagaa ggctgtcaaa gcggccatag ttggcaccat
     5821 ttggatgatc aagaagaaga ccaaactttg tttacgagcc aagaagttgt aacggctgta
     5881 agcataacca gcaagtacga tgatacttgt ttgaacagcc atggtaatta aggcgataat
     5941 caaagtgttg aggtaccaag taccgtacaa ggtttcagtg aagaggcctt taaagttatc
     6001 aaaattgagg tcgatattag tatctagttt aaaggctgag acgttacctg ctttaaaggc
     6061 tgacatgatg gtaatcaaca gtggatagat aattacaatt gatagaccaa tcaggtaaag
     6121 gtaagtaagg ctttgagtca gtctacgttt gagtttaatt gagttattca tcttagacgt
     6181 cctccatatc aaatgcgtgt agtttcttga atgcgatcat agagattgag atgacaatga
     6241 tagagataat caaggtaaca gctgccgcca ttgagtattg aggagatgta cctgttgtca
     6301 aacggtagat ccatgagatc aagatatcgg ttgaaccagc tccacctccg acactaccag
     6361 gtcctccacc attgaagagg tacatgatag agaagttgtt aaagttgaag gtgtattggc
     6421 taatcaaagt aggtgccgca acagccaaaa tcattgggaa agtgatgttg cggaattttt
     6481 gccaagcgtt ggcaccgtca atataagctg cttcgtaaag gtcgttagga atagattgca
     6541 agatacccaa agtcaaaacg tagatgtatg ggaatccgag ccaaccttgc atcataatca
     6601 aggcaatctt agtccaagtt gggtctgttt tccaaggaat aagagctcca tcaaggaaag
     6661 gaaggaattt agccaagatt ggcaatactt gagtgttgat agcaccgaca ctatcgttaa
     6721 acatgtttga gaatgtcaag atagtgatga aggctgggac agcccaagga agaaggaaaa
     6781 taacaccaaa gatacgtttt cctttgataa atggttggtt ggcaatgata gctgtgaaga
     6841 taccaattac gatttgtaaa gtagaagctg ccaaagccca aatgatagtc caagaaagaa
     6901 cagaaccaaa ggcagaacgg aaggtactca agctccaaat gtttgtaaag ttggtcaaac
     6961 caacccagtc caacaacttg tttggtggca agtgttggaa gtcgtagttg gtaaaggcga
     7021 tcatcaaggt tacgataact gggaagataa tcgcgaaggt catggcaaca taagatggaa
     7081 tgatcaagag gtaagggaag ccattttcat aaatcccttt gatcatgtct ttgagtgtgc
     7141 gtggaactgg aattccattg ttaatgcgtt ttgcaatcgt atgtgcatct ttgatatttg
     7201 agaaataaaa gagtacataa acgattacaa agattagatg gaaggcacca cgaatcagca
     7261 taaagaggga attatcacga cctggtttgt caccaagagt gatgaggttg ctcaattcag
     7321 gggttgcaag tgctaggaag taaaggacaa atacgatggt tacaccaagg aagataaaac
     7381 ctttggcttt ttgtttattg taaatctgtc ctaacccagg aatgatagac agcagggctg
     7441 ctttactagg ttgttgcttt tccatattaa ctcctttcat aggatactac ttttttataa
     7501 gaaagctaaa ttatttgtgt ctctattgat aaattcaaag ggggatttga tttccacccc
     7561 ccttgaacaa attttttatt caccaaattt ttgtttgatt gtttctttga tcaatgttac
     7621 agcatcgtta gcagctgttt tagcatcttt ttgaccactt acagcatcaa agagcatatt
     7681 tttcgctgga tcccaaactg cagacatttg agagatgttt ggcagtggtt gagtgttctt
     7741 gaactgtttg ataacagctg ttgtcaactc atcgttttta ccttcagcgt atgaacgagc
     7801 ctcagtatta gctgggattt cgttagtctt atcatataat actttttgtt gttcagttgc
     7861 aacaaggaag tctacaaatt tttgagaagc ttcaaggttc ttaacggctt gaggaatgac
     7921 ccaagcttta ccaccaccga atgcagcata ttcttttcca tttggaagag ttgggatagt
     7981 tgcaactccg tagtttactt tagcatcttt aaaggcttga gctttccaag gtccgtcgat
     8041 gatagcagct gttttacctt cttggaattg agtttggatt aagtttccag caccttctgt
     8101 atcttgcata cctttaggcc atttttcgta ccaagattta gcgtagttga tacctacgat
     8161 agaaccgtcg tttgcaagac cgatgtcttt agcgtcttta ccgttttggc caaagacgta
     8221 agcaccgtta ccggcaagaa gtccatatgt atagtagaag tttgtccagt cagctaggaa
     8281 ggcagtagtt ttaccatctt caccagcgaa tgcgtatttg ctatctttag caaggttttc
     8341 caagtcagca aatgtttttg gagcatcttt caccaagtct ttgttgtagt acataacaag
     8401 tgactcgata acggcaggag caccgtaaac tttaccatta gcagctgtta caagagattt
     8461 agttgtgtcg tctgttttag caccatcgct caatttcact tctgaaagtt gtccgtcaga
     8521 accaaggcta cctacacggt cgtatggagc catcataaca tcagggacat taccagattg
     8581 gttgtcaaga gaaagtttat caagacctcc tagagcatca ccagttttaa gagtgacttt
     8641 tactccagct tctttttcat aagctttagc aacctcttca atatagctct tatatccctc
     8701 gtctacatat acagtgagtt ctttgacttc agatgaacca gaatcagcag gcttatcagc
     8761 agttttgctt ccgcaagcta ccaaaagcaa gctagcaagt gtaacagttc caagcaccgc
     8821 agcgctcttc ataaatttag atgacatagt gtattcctcc caaagaatag caagttttat
     8881 tgataaggaa acgcaaacgt tttcctttat gagcttagta tagcacaaat agaaaacggt
     8941 tgcaagtatt ttttgtaaaa attttaaaaa atttttaagc ttgatttgat agcataattt
     9001 tgcattttaa tagaagaaaa gtatgaaata gataagaata cagtattttt aataaaaata
     9061 tatggaatat gtctaaagag ggaaaccagg aggggctacc tccctggttc taatccctat
     9121 ctattttcta tggacgtttg tgctttgtta catataaatt caagctccct aaggaggttt
     9181 tgtactttgt agactgtctc gtgagagtca aaccttagga ttagatagtt ttaagttatc
     9241 tttgctaaaa tgagttagtc tccttaaaaa taatcaaaaa agttttttaa aaacgcttgc
     9301 aattatgctt gaaaaggagt atacttataa gtaacgcaaa cgtttgcgtc tgcaaaatac
     9361 gcaacgttcc attattttaa cacacgaggt gctattatga aaaaacgtca aagtggtgtg
     9421 ttgatgcaca tctcttctct tccaggagct tacggaatcg gatcatttgg tcaaagtgct
     9481 tacgacttcg ttgatttctt ggtccgtaca aaacaacgtt actggcaaat ccttccatta
     9541 ggagcaacta gttacgggga ttctccttac caatctttct cagccttcgc aggaaacact
     9601 cattttatcg atttagatat cttggtggag caaggtttgt tggaagcaag tgaccttgaa
     9661 ggagttgact ttggtagcga tgcgtctgaa gttgactatg ctaaaatcta ctatgcacgt
     9721 cgtcctcttt tagaaaaagc ggtgaaacgt ttctttgaag tcggagatgt taaagatttt
     9781 gagaaatttg ctcaagacaa ccaatcatgg cttgagctct ttgctgagta tatggctatc
     9841 aaagagtatt ttgacaatct tgcttggact gaatggccag atgcagatgc tcgtgctcgt
     9901 aaagcttcag cacttgaaag ctatcgtgag caattggcag acaagttggt ttaccaccgt
     9961 gtgactcaat acttcttctt ccaacaatgg ttgaaattga aagcttacgc taacgacaac
    10021 cacatcgaaa tcgttgggga catgccaatc tacgtagcgg aagattcaag tgatatgtgg
    10081 gcaaatccac atctcttcaa aacagatgtc aatggtaagg ctacttgtat cgcaggatgc
    10141 ccaccagatg agttttctgt aactggtcag ctttggggta acccaatcta tgactgggaa
    10201 gcaatggaca aagacggcta caaatggtgg attgaacgct tgcgtgaaag cttcaaaatc
    10261 tacgatatcg ttcgtatcga ccacttccgt ggcttcgaat cttactggga aatccctgct
    10321 ggttccgata cagcagcacc tggtgagtgg gtgaaaggtc caggctacaa gctttttgca
    10381 gccgttaagg aagaacttgg tgagctaaac atcatcgcag aagaccttgg cttcatgaca
    10441 gatgaagtga tcgaattgcg tgaacgtact ggcttcccag gaatgaagat tcttcaattt
    10501 gccttcaacc cagaagacga aagcattgat agcccacact tggcacctgc taactcagtt
    10561 atgtacacag gaacacacga taacaatacg gttcttggtt ggtaccgtaa cgagattgat
    10621 gatgcgactc gtgagtacat ggctcgttac acgaaccgta aagaatacga aacagtggta
    10681 cacgctatgc ttcgtacagt attttcatca gttagcttta tggcaattgc aactatgcaa
    10741 gatttactag aattggatga ggcagctcgt atgaacttcc catctaccct tggtggaaac
    10801 tggtcttggc gtatgactga agatcaattg acaccagctg tcgaggaagg tttgcttgac
    10861 ttgacaacaa tttatcgccg aattaatgaa aatttggtag atttaaagaa ataagacaat
    10921 aatcaggaga caactaaaca tgttatcact acaagaattt gtacaaaatc gttacaataa
    10981 aaccattgca gaatgtagca atgaagagct ttaccttgct cttcttaact acagcaagct
    11041 tgcaagcagc caaaaaccag tcaacactgg taagaaaaaa gtttactaca tctcagctga
    11101 gttcttgatt ggtaaactct tgtcaaacaa cttgattaac cttggtcttt acgacgatgt
    11161 taaaaaagaa cttgcagctg caggtaaaga cttgatcgaa gttgaagaag ttgaattgga
    11221 accatctctt ggtaatggtg gtttgggacg tttggctgcc tgctttatcg actcaattgc
    11281 tactcttggt ttgaatggtg acggtgttgg tcttaactac cactttggtc ttttccaaca
    11341 agttcttaaa aacaaccaac aagaaacaat tccaaatgca tggttgacag agcaaaactg
    11401 gttggttcgc tcaagccgta gctaccaagt accatttgca gactttactt tgacatcaac
    11461 tctttacgat attgatgtta ctggttatga aacagcgact aaaaaccgct tgcgtttgtt
    11521 tgacttggat tcagttgatt cttctattat taaagatggt atcaactttg acaagacaga
    11581 tatcgctcgc aacttaactc tcttccttta cccagatgat agtgaccgtc aaggtgaatt
    11641 gctccgtatc ttccaacaat acttcatggt ttcaaacggt gcgcaattga tcatcgacga
    11701 agcaatcgaa aaaggaagca acttgcatga ccttgctgac tacgcagttg tccaaatcaa
    11761 cgatactcac ccatcaatgg tgattcctga attgattcgt cttttgactg cacgtggtat
    11821 cgagcttgac gaagcaatct caattgttcg tagcatgact gcctacacta accacacaat
    11881 ccttgctgaa gcgcttgaaa aatggcctct tgaattcttg caagaagtgg ttcctcactt
    11941 ggtaccaatc atcgaagaat tggaccgtcg tgtgaaggca gagtacaaag atccagctgt
    12001 tcaaatcatc gatgagagcg gacgtgttca catggctcac atggatatcc actacggata
    12061 cagtgttaac ggggttgcag cacttcatac tgaaatcttg aaaaattctg agttgaaagc
    12121 cttctacgac ctttacccag aaaagttcaa caacaaaaca aacggtatca ctttccgtcg
    12181 ttggcttatg catgctaacc caagattgtc tcactacttg gatgagattc ttggagatgg
    12241 ttggcaccat gaagcagatg agcttgaaaa acttttgtct tatgaagaca aagcagctgt
    12301 caaagaaaaa ttggaaagca tcaaggctca caacaaacgt aaattggctc gtcacttgaa
    12361 agaacaccaa ggtgtggaaa tcaatccaaa ttctatcttt gatatccaaa tcaaacgtct
    12421 tcacgagtac aaacgccaac aaatgaacgc tttgtacgta atccacaaat accttgacat
    12481 caaagctggt aacatccctg ctcgtccaat cacaatcttc tttggtggta aagcagctcc
    12541 agcctacaca atcgctcaag acattatcca tttaatcctt tgcatgtcag aagttattgc
    12601 taacgatcca gcagtagctc cacacttgca agtagttatg gttgaaaact acaacgttac
    12661 tgcagcaagt ttccttatcc cagcatgtga tatctcagaa caaatctcac ttgcttctaa
    12721 agaagcttca ggtactggta acatgaaatt catgttgaac ggagctttga ctcttggtac
    12781 tatggacgga gctaacgtgg aaatcgctga gttggttggt gacgaaaaca tctacatctt
    12841 tggtgaagat tcagaaactg ttatcgacct ttacgcaaaa gcagcatata aatcaagcga
    12901 attctacgct cgtgaagcta tcaaaccatt ggttgacttc attgttagcg atgcagttct
    12961 tgcagctgga aacaaagagc gcttggaacg tctttacaat gaattgatca acaaagactg
    13021 gttcatgact cttcttgact tggaagacta catcaaagtc aaagagcaaa tgcttgctga
    13081 ctacgaagac cgtgacgcat ggttggataa agtcatcgtt aacatttcta aagcaggatt
    13141 cttctcatct gaccgtacaa tcgctcagta taacgaagac atctggcact tgaactaata
    13201 ctcttcgaaa atctcttcaa accacgtcag ctttatctgc aacctcaaag cggtgctttg
    13261 agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaaa
    13321 tttatactaa tacattttgt aaaaaagcga gtttcgattg aaattcgctt ttttaaatgc
    13381 tgtggatttg ggtcaatctt gtctaaaaat agggaaatcc tagatacagt gaaggcttta
    13441 aatgctggtt tttactgtct ttagccttat attttttcgt agttggttac ctcatatctc
    13501 ttgtattcgc ttacataaag tattataata taattgtagg aaagaaggtg tttttatgat
    13561 atacacactt aaattggtgt tgtttattac ctttcttgta ataagcttgt tacctgataa
    13621 gatttttgga aaaaataaaa aaatttggaa aatagttttt gcaatattga cggcagtggc
    13681 agcattgtca tttatgtact aagttatttt aagaatgtag ggaaataaac cctacattct
    13741 ttttagtttt ttctgttttc taaattctat ttatccaagc gcttcaacat ttcttgcttc
    13801 ttcgcttcaa gttctgcacg cttttcttcg atttcggcat gttttttctc gagttcagaa
    13861 caacttgcat cattgctaaa ttcttttcgc catcaggaga tagggtgagt cgacatgtct
    13921 attactcacc caaagcagtc ctacaaagca ggaattttct gttacttttt tggaaatagt
    13981 aacgtttata cagctttgac acttcgtatc aaagcgccaa acacactccg agggatttac
    14041 agaaagcaga aaaggaatga tctggtataa gatcattcct tttctctctt tttctttaag
    14101 taattatata caatgtacga cgaagtcgtc attgcaatgc tgatccacca cctaaaggga
    14161 actttaaaca agattgataa gataaagaat ataaacaacg aaaatacgtt atacccaatt
    14221 aattttattg tatatctcat gattaaaagt taatccttct gttgttagga atggcatcat
    14281 ttttatccca taattgtgct aaataagtcc ccggtgataa taaattcata gcgaattcta
    14341 aagcaacatc atttacaaac caactaccta gatatctaga aattgctgaa cgaatagcac
    14401 tttttgctgc atgttttcct tttactttaa ttagatttgc aaggcctgca gtagttcctc
    14461 ctaatgctaa agctattgca gtatctaata gagcacccat ttgattaact gtaatacctt
    14521 gccaagctgc tctaaatgga gagtatgtag gtgggattgt ataatcgcct tgtaattgtc
    14581 ggttaattac ttctttgatc cattgttgtg agacgtctgg atgaaaagat tggatttcgt
    14641 ttgcaagtgt attgatttgt tcttctgtta gagaagtgac aggttgaagt tccatatttg
    14701 tttcaatttg tgatacttgt tcagaagcgt atacagctga aacacttgga atcgctgata
    14761 caattaacac aattgacgtc aaaaaaaccg aaataaattt cattaatttg ttcatgaact
    14821 tttctccttt ttatttgtat ctgcttacat tttatcatat actgttatta tagtcaaaaa
    14881 aatatgctat tatgttaaaa aaatattttt caaaatataa atggacggat ttattttgga
    14941 ttttatttgt tattttgacc tgcctctata ttggtaacca tgatttgttt actctcaatc
    15001 atcaagaatt ctcttttcgt ggtagcgttt ggggtctggt actggcctta tatcacttac
    15061 tattcattga taagtttgtt atatcgaatc gaaaataaag attagagcta tgcttgactg
    15121 gctactttta ggattgattt tggaggaaga ttttgtctct attatttatt attttaaatt
    15181 tatttatttt gtataagatc tattctttga ggcgggaaaa atcgaaatac ttgatttata
    15241 cggcctatat catatttggg gtaaatgtag tatatggtat tcaatggtta ttaaaagaac
    15301 tgatttcaac tatttcccct taatgtgtat ggaaactata acaaaacgca taagattaag
    15361 gtttgtgtac ctgttcttat acgtttttgt catattgaag attttcggta agttttctac
    15421 ttttgcgaag tctagtttat actcaatgaa aatcaaagag taaactagcc gtaggttgct
    15481 caaagtacag ctttgaggtt gcagataaaa ctgacgaagt cagctcaaaa catggttttg
    15541 aggttgtaga tgaaactgac gaagtcagct caaaacatgg ttttgaggtt gtagatgaaa
    15601 ctgacgaagt cagtaaccat acgtacggca aggcgacgtt gacgtggttt gaagagtatt
    15661 agaatgcttt cccaaccaaa atctctgctt cgatggtaat ctctgtcagt tggctccagt
    15721 caatcttgct ctggtcaacg tgaaagagga gaggagtcat actgagtagg gcttggagtt
    15781 gttctgctgt gatagtctta gtcagagagg cagtttgact agataggatg gtaaagtgtt
    15841 cctggaaatg ctccttgata tcttggttag aatactcctt gtttgtcagc tggtcctgta
    15901 ctctttgacg gatttctttg aggtgatttt cagttgggat aacctttatc aagataccgt
    15961 ctttggataa aacgcgacga aattctccat agttggcagg tgagaagata tcaagcagga
    16021 tatccatgct agcgtctttt ataggaaggc gtgccaagtc gccaacgaac caattgactg
    16081 cccagttggg ttcactttta gcagcgattt ggactgaatc tttggagatg tcaaaggcat
    16141 agaaagtttt ttcagagtga ctttcttgta gtttgcgaga atagaatcct tcaccacaac
    16201 cgatatccaa aattgttgtg gtagtttttg agcttgcaag caagtcagat acagcatcta
    16261 agatagcttg gtaaaagccg gcttctagga tttgttgacg gttttgaaaa ttttccttgt
    16321 catagttagc agattgcttg atttgaggtg ctagattgac atagccaaat ttcgccaagt
    16381 caaaagaatg atggttgcag cacttgaaat tagtctctaa cagagtcaga ttttcttgac
    16441 agataggaca ggcaaaggca gtcgcagaag caaaacgctg aagtttgggc ttgagatttg
    16501 tattcatagt ttaagtgtat caaaagaggc aaatgaaagc aactttagga ataagtagat
    16561 gggagattca gtagaaataa aactaattct ccaatttata gaatgaaatt gcttttatat
    16621 ctaaattgct atataataat gataaggagg aaataagtat gttaaaagaa gtattaaccg
    16681 ttgcaaaagt tgcgaaaaaa tcttcattat ttttgggtgg tgtcgcattt ggtacccttg
    16741 gtttgaaaat cttagcaagt aaggaagcta aaaaaggtta ttctaaagct ttggctaagg
    16801 cttacaagtt gaaagacgag ctagatgcat ctgtttctgt cgtgaagcaa catggagacg
    16861 atgtcttgca agatgccaaa tatttgtacg agcaagagaa aaaagaagag caattagata
    16921 gccttatagg tgaataatat gtcttttaaa gtgctacata gaggatacca acatatccga
    16981 ctatcatctt ctttttcact taccttggat attcaagact atcttcgttc cttggcgaga
    17041 gatgaaaagg ggattgagtc tatccagttt tacatggatc aacagcactt tactctacgc
    17101 ataaaagaag gcttttctgt attagataat gcagaagcct ttttaaaaag aattgataaa
    17161 gggaaagttt ctgagttgat gactcttccc attcgtagag aagagagtgc ttattctatt
    17221 gtttcaggtg cagcggttaa gcgtgtactt tttcgtagtt ttgtgccgta tcctattcgc
    17281 tatatatgga cttgttatca ggctttgggt tatattagag aagcctatca aacactagcg
    17341 cgtaaggaac taacgatgga agtcttggac tgttcggcta ttttattgtc tttgtttatg
    17401 aaccaatcca agacagctag caatatcatg tttatgcttg atttggggaa tcatttagat
    17461 cagtggtcct tgaaaaaaac tgcaacagat ttagaacaga gtcttcttgc aaaagagagc
    17521 gatgtattcc tagtacaggg cgatacggtt gttagtatca agagttccga tgttcaaata
    17581 ggagatgtct tgatcttatc tcaaggaaat gaaattctgt ttgatggaca agtagtttca
    17641 ggtttaggta tggtcaacga aagttccttg acaggagaga gttttccagt tgaaaaaaga
    17701 gagtctgatt tggtttgtgc aaatacagta ttagaaactg gagagttacg cattcgtgta
    17761 acagataatc agatgaacag ccgtatttta cagctgattg agttgatgaa gaaatctgaa
    17821 gaaaacaaga aaacgaaaca acgctatttc atcaagatgg cggataaagt cgtcaaatat
    17881 aatttcttgg gggctgggct gacttaccta ttgacaggtt ctttttctaa ggctatttct
    17941 ttcctattgg tcgatttctc ctgcgctttg aaaatctcta ctcctgtagc ttatttgaca
    18001 gttatcaagg aagggttgaa ccgtgaaatg gtgattaagg atggagatgt tctggagaaa
    18061 tatctggaag ttgatacttt cttgtttgat aagacaggaa caatcacaac tagttatcct
    18121 atagttgaaa aggtgttacc ttttggagac tatagtgagg aagatattct cagaatcagt
    18181 gcctgtcttg aggaacacat ttatcatcct attgctaatg ccatcgtcaa gcaagctgag
    18241 atagagggaa ttgaacatga ggaaatgcat gggaaactcc aatatatcgc aagcaagggg
    18301 atcaaatctc atatagatgg ccaaccagtt cttattggga attatgtctt gatgcaggat
    18361 gagcagattc atatcagttc agaacaaaat gctttaattg aagagtacaa gagtcactac
    18421 aatctcttat tcttggctta tcaaaatgaa ttgattggaa tgttctgcat tcatactcct
    18481 ttgagaaaag aagcaaaaac agccttggat aaacttaagg cacaggggaa aaaattgatt
    18541 ctggcaacag gagacacctt gattaggaca gaggaattag tcaaagattt gccctttgat
    18601 caggtctata cagacttgaa acctgatggg aaatttgagt tagtagagaa actgcagaaa
    18661 gcaggtcaca ctattttgat ggttggagat ggcttgaatg actcagcggc tttaactcta
    18721 tcagatatcg gtgtggtgat gaatgagagt gcagatattt ctaagcagat gagtgatatc
    18781 ttattgttag ataatcgttt ggatttcttc caagagttgg attcgttatc atcatctttg
    18841 caaacactca tcaagaaaaa tattcaggat accgttgtcg taaatagtag tttgattggc
    18901 tttggcttat ttaattggtt cagtccttca aatctctcta tcttacataa tctaacaacc
    18961 ttgcgcattg tcctgcgtag cctgtctatt aaaaatagat agatgagagt tattaacagc
    19021 aaaaaggagt tacctttctc gaggttaact cctttgttta tagatagatg ttgaatagtt
    19081 tagtaagtca atacaaagta ttttttcttc ccacgacgga taacagtcag ttcattttct
    19141 aacttatcag cgtcactcaa gacatagtca aggtcttgga tgcggtcgcc gtttacgtag
    19201 atggctccgt tttggacgtc ttcacgggct tggcgttttg agttaactat accagatgag
    19261 acgagcagtt ccacgatatt gttgttttcg tctgcctgta cttggtagtt tggcacacca
    19321 cgaagtcctt gtttgagctc tttgacagaa aggtttttga tgtttcctgc aaagagttgc
    19381 tcagtgatgt taagtgcttc tttgtaggct tcttctccgt gaacaagtgt aacaacttca
    19441 cgagccaaga ctttttgagc caagcgttcg tgtggcgctg cttcaaattg tttacgaata
    19501 tcttcaatct catcaagtga caagaaagta aagattttca agaagcgaac agtgtcagcg
    19561 tccatcacgt tcatccagaa ttggtacatt tcgtatggag aagtcttttc gggattaagc
    19621 cagacggcat ttccttctga tttaccaaat ttcttaccag ttgcatctgt gattagtgga
    19681 acagtgataa cgtgaccagt cttgtccgcc ttacgacgaa gcaattcggt accagctgtc
    19741 atatttcccc actggtcaga accaccgatt tgaagagtga cattatggtc ttggttaagg
    19801 acgaagaagt cgtacccttg catgatttgg taagcgaact cagtgtaaga aattcctgtt
    19861 tcgatccgtt ttttaacaga ttccttactc atcatgtagt tgaccgtgaa gtattttcca
    19921 atatcacgga ggaagtcaat gaagctgatg ctgccaaacc agtcgtagtt gttgaccatg
    19981 acagccttgt tttcgccatt ttcaaagtca agaaaacgag aaagttgtcc ttggatagac
    20041 ttgacccagc catctactgt gtcttttgtt tggagactac gttcagcatc tttgaaggac
    20101 ggatctccga tgagacctgt agcaccgcca acgagcgcat aaggtttgtg acctgctagt
    20161 tgcaagcgac gacttgtcaa gattgcgaca aggtggccta ggtgaaggct gtcagcagtt
    20221 ggatcgtagc cagtataata agaaacttga ccttcttcta gggctttacg caaagcttct
    20281 tcatcagtcg tttgaaatat caaaccacga tcttttagct catcaaaaat gtgcatgtgt
    20341 cttttctcct ttttaaaatt attgtttcta cctattgtat cacaaacttg ggcaatagcc
    20401 tagcagaata gggaagaaag tggctatttt attgaaaatt tcccttttgt ggtataatag
    20461 atagagtgag gaaatccatg caaaatcaat taaatgaatt aaaacgaaaa atgctggaat
    20521 ttttccagca aaaacaaaaa aataaaaaat cagctagacc tggcaagaaa ggttcaagta
    20581 ccaaaaaatc taaaacatta gataagtcag ccattttccc agctatttta ctgagtataa
    20641 aagccttatt taacttactc tttgtactcg gttttctagg aggaatgttg ggagctggga
    20701 ttgctttggg atacggagtg gccttatttg acaaggttcg ggtgcctcag acagaagaat
    20761 tggtgaatca ggtcaaggac atctcttcta tttcagagat tacctattcg gacgggacgg
    20821 tgattgcttc catagagagt gatttgttgc gcacttctat ctcatctgag caaatttcgg
    20881 aaaatctgaa gaaggctatc attgcgacag aagatgaaca ctttaaagaa cataagggtg
    20941 tagtacccaa ggcggtgatt cgtgcgacct tggggaaatt tgtaggtttg ggttcctcta
    21001 gtgggggttc aaccttgacc cagcaactaa ttaaacagca ggtggttggg gatgcgccga
    21061 ccttggctcg taaggcggca gagattgtgg atgctcttgc cttggaacgc gccatgaata
    21121 aagatgagat tttaacgacc tatctcaatg tggctccctt tggccgaaat aataagggac
    21181 agaatattgc aggggctcgg caagcagctg agggaatttt cggtgtagat gccagtcagt
    21241 tgactgttcc tcaagcagca tttttagcag gacttccaca gagtcccatt acttactctc
    21301 cttatgaaaa tactggggag ttgaagagtg atgaagacct agaaattggc ttaagacggg
    21361 ctaaggcagt tctttacagt atgtatcgta caggtgcatt aagcaaagac gagtattctc
    21421 agtacaagga ttatgacctt aaacaggact ttttaccatc gggcacggtt acaggaattt
    21481 cacgagacta tttatacttt acaactttgg cagaagctca agaacgtatg tatgactatc
    21541 tagctcagag agacaatgtc tccgctaagg agttgaaaaa tgaggcaact cagaagtttt
    21601 atcgagattt ggcagccaag gaaattgaaa atggtggtta taagattact actaccatag
    21661 atcagaaaat tcattctgcc atgcaaagtg cggttgctga ttatggctat cttttagacg
    21721 atggaacagg tcgtgtagaa gtagggaatg tcttgatgga caaccaaaca ggtgctattc
    21781 taggctttgt aggtggtcgt aattatcaag aaaatcaaaa taatcatgcc tttgatacca
    21841 aacgttcgcc agcttctact accaagccct tgctggccta cggtattgct attgaccagg
    21901 gcttgatggg aagtgaaacg attctatcta actatccaac aaactttgct aatggcaatc
    21961 cgattatgta tgctaatagc aagggaacag gaatgatgac cttgggagaa gctctgaact
    22021 attcatggaa tatccctgct tactggacct atcgtatgct ccgtgaaaag ggtgttgatg
    22081 tcaagggtta tatggaaaag atgggttacg agattcctga gtacggtatt gagagcttgc
    22141 caatgggtgg tggtattgaa gtcacagttg cccagcatac caatggctat cagaccttag
    22201 ctaataatgg agtttatcat cagaagcatg tgatttcaaa gattgaagca gcagatggta
    22261 gagtggtgta tgagtatcag gataaaccgg ttcaagtcta ttcaaaagct actgcgacga
    22321 ttatgcaggg attgctacga gaagttctat cctctcgtgt gacaacaacc ttcaagtcta
    22381 acctgacttc tttaaatcct actctggcta atgcagattg gattgggaag actggtacaa
    22441 ccaaccaaga cgaaaatatg tggctcatgc tttcgacacc tagattaacc ctaggtggct
    22501 ggattgggca tgatgataat cattcattgt cacgtagagc aggttattct aataactcta
    22561 attacatggc tcatctagta aatgcgattc agcaagcttc cccaagcatt tgggggaacg
    22621 agcgctttgc tttagatcct agtgtagtga aatcggaagt cttgaaatca acaggtcaaa
    22681 aaccagggaa ggtttctgtt gaaggaaaag aagtagaggt cacaggttcg actgttacca
    22741 gctattgggc taataagtca ggagcgccag cgacaagtta tcgctttgct attggtggaa
    22801 gtgatgcgga ttatcagaat gcttggtcta gtattgtggg gagtctacca actccatcca
    22861 gctccagcag ttcaagtagt agttctagcg atagcagtaa ctcaagtact acacgacctt
    22921 cttcaagggc gagacgataa ttctctaaat gaagtggcca atcaatggat tgccactttt
    22981 ttcctttcgt gttacaataa gggtatgaat cagtatcaga aaaagattgt taacggaaaa
    23041 atttattcgc tcctatccgg cttaatatgg ggaatctgtg gaattttagg agagtacttc
    23101 tttactcatt atcaggtgtc ttcgggctgg attacctcta tgcgtttgac actggcaggg
    23161 agtcttgtac tcatttggtc tgcaatacaa ttaaaatcgc aagtgctaga tatttggcga
    23221 gacaagaaaa attacctgcc ctttttagcc tatgctattt tggggatttt ttcagttcag
    23281 tattttttct atctctgtgt agaatactca aatgctacga cagcaactat tttacagttt
    23341 attagccctg tctttatcct cttttataat cgcttggttt atcaaaaacg agcgtcaaaa
    23401 agcgctgttt tctatgtttt ggttgccatg ctgggtgttt gcttgatggc gacaaaggga
    23461 gatctctctc agttatccat gacgccgcta gctcttataa caggtttgct gagtgccatg
    23521 ggtgttatgt ttaatgttat cttgccccaa ccttttgcta agcgttatgg ttttgttcct
    23581 acggttgggt gggggatgat tttggcaggt ttgtttagca atgtcctctc gccggtttat
    23641 cagctttcct ttactcttga tatttggagt atcttgattt gcctcattat cgctttcttt
    23701 ggaacggctt ttgctttttt catttccatg aaggctgtgt ccttggtttc tcctttggtg
    23761 gttgccgtta tcagtgccag tgaacctctc tcttctgctc tcttgagtgt tttgttctta
    23821 ggattagtag tggattggtc cctccttcta gctatagcct tgattatttt acccatgata
    23881 tttttgtcta tagaagaagc gaaagaaagt agataaaaag tcttttctta attctaaaag
    23941 tgtgctatac tagaatagtc aataaaacac ggggagatag ttgtgaagag tgtttttagg
    24001 ttgtatcggt aggggcttgc ttttaccgac agcacgtttt atctcacatc cctaaaaaat
    24061 catacctaaa aacagacaaa aaggtttcaa atttgaggcc ttttttggta gaataggtat
    24121 cattataacg aaccaggagg cacctatgac tgctacaaaa atgaacgctc aagaaattat
    24181 ccaatttatc gccaatgctg aaaagaaaac cagtgtcaaa gtaacctttg aggggcaact
    24241 cgcaactgct gtgcctagct ctgttgtcaa actaggaaat gtcctattcg gagactggaa
    24301 ggacgtggct ccgcttcttg aaggtttggt agaaaatcaa gattatgttg tcgagcaaga
    24361 tgctcgtaat tctgcagttc ctttgctaga taagcgtgct atcaacgctc gtatcgagcc
    24421 aggtgctatt atccgtgacc aggtggaaat tggtgacaat gctgttatca tgatgggagc
    24481 tgttatcaat atcggtgctg aaatcggtgc tggaaccatg attgacatgg gtgccatcct
    24541 tggtggccgt gctatcgttg gaaaaaatag ccacgttggt gcaggtgcag ttttggcagg
    24601 tgtgattgag ccagctagtg ctgaaccagt ccgtgtcgga gacaatgttc ttatcggtgc
    24661 taatgcagtg gttatcgaag gagtccaaat cggtagtggt tcagttgtcg ctgcaggagc
    24721 tatcgttacc caagatgtcc cagaaaacgt ggtagtagca ggtgttccag ctcgtatcat
    24781 caaagaaatt gatgcccaaa cccaacaaaa aacagcgcta gaggatgcgc ttcgtacctt
    24841 gtaattgtaa aagtaaaaaa gaggcggaac cctttttcca gcctctttct gctatatcgg
    24901 aggacagata gatgttagat ttgattcaga ctagacgagc tttacaccag attccagaga
    24961 ttggcttgga ggagttcaag actcaggctt atttgctgga tgtgattgag aaattgacta
    25021 cgggcaagga ttttgttcaa attcgtactt ggcggacagg gattttggtc tacctgcagg
    25081 gaagtcagcc ggagcgaacc attggttggc ggacagatat tgatggcctg cctatcgtcg
    25141 aacaaacagg tctacctttt gcttctcaac accaaggtcg catgcatgcc tgtggccatg
    25201 attttcatat gaccattgcc ttaggctgtc ttgagcgcgc ccttgaggag caacccaaga
    25261 ataatctgct ctttctattt cagcctgctg aagaaaatga agctggtggt atgctcatgt
    25321 atgaggatgg tgcttttgga gattggttgc caaaccaatt ctatggtctc catgttcgtc
    25381 cagatttgaa agtcggccag attgcgacta atactcatac actctttgca ggaacttgcg
    25441 aggtgaagat ccgtttcaaa ggcaaaggtg gccacgcagc ttttcctcat gaagccaatg
    25501 acgccttggt ggcggctagt tactttgtga cccaagtgca gtcagttgtt agccgcaatg
    25561 tcaacccaat cgagggagca gtggtgacct tcggcgtttt tcaagctgga accaccaaca
    25621 atgtcatcac agacacagct tttttacatg gaactattcg tgccttgaca caggacatga
    25681 gtctcttggt gcaaaagagg gtaaaaacag ttgcagaagg ggttgcagct gcctttgata
    25741 tggaagtcga agtggaactc aaacaaggtg gatacctacc tgttgagaac aatccagcct
    25801 tggcgcgtga actgatggac ttctttgacg aaaaagacgg aatcgagttg attgatatcg
    25861 aacctgctat gacaggcgag gactttggtt atctcctttc aaaggttgat ggcgtgatgt
    25921 tttggctagg tatcgatagt ccctacgctc ttcatcaccc tcaaatgagt cctaaggaag
    25981 aagtcttagc tattggggtg gctgcggtgt ctagtttcct gaaaaagaag gcagcagaat
    26041 agagggcttg tctatgaaat cggaattacg caagcaagtc ttgcaaggaa tgaaggctat
    26101 atctcaagaa caaaaacagt ttatagatca aactttaacc gagcggcttt tacaccatcc
    26161 cttctatcaa gaagccaagg tcatcgcaac ctacctctct ttttctcatg agtttcaaac
    26221 gcgggaactg attgagcagg cgctgaagga cggcaagaag gttttaatac ccaaaactta
    26281 tcccaagggg cgcatggact ttgtagtcta tgatctgcag cagttggtaa aaactgcctt
    26341 tgccttactg gagccacagg gagatttgga agtggtggat gtatctcaga ttgatttgat
    26401 tcatgttcct ggcctggctt ttacgacgga tggatatcgg attggatatg gtggaggtta
    26461 ttatgaccgc tatctggaac atttttctgg tcatactttg agtacggttc atccttgtca
    26521 aattcaggac tttatacctg aaaaccatga tattcctgtt caggaggtat taattgatga
    26581 aggaaatctt tgatagacgt taccctgtga cgagtttctt cctcttagtg acggccttgg
    26641 tatttttact aatgttggtc actgcaggcg ggaactttga cagggcagat acattatttc
    26701 gatttggagc catgtatggg ccagctattc gcctctttcc cgagcaggtt tggcgtctct
    26761 tgtctgccat ttttgttcat attgggtggg aacatttcat tgttaatatg ctttcacttt
    26821 attatcttgg aaggcaggta gaggagattt tcggttctaa gcagtttttc tttctctatc
    26881 ttttatcagg aatgatgggc aatctctttg tttttgtatt tagtcctaaa tccttagcag
    26941 caggcgcctc tacctctctt tatgggctat ttgccgcgat tattgttctt cgctatgcaa
    27001 ctcgcaatcc ttatattcaa cagctagggc aatcctatct gacacttttt gtggttaaca
    27061 ttattggaag tgttctgatt ccaggaatca gcctagcagg ccatatcggt ggtgcagttg
    27121 gtggcgcatt tctagcagtt atctttccag ttagaggaga aaaacggatg tataatacca
    27181 gccagagatt aggagcggta gtcttgttcg taggactcgc cattttgctt ttctacaagg
    27241 gaatgggaat gtgacgaagt tgaaagaaaa tttgtgtaat gaaaaaagat aaggcatttt
    27301 ttgaacctta tctttttatt ttattccttc tcagtcaatt cttttccaag ttggatgagg
    27361 taattcttca aatcatcttt gacttgtgga tgtttgaggg cgtagtcaat agatgttttc
    27421 ataaagccaa acttatcccc aacgtcgtaa cgagctcctg taaattcacg ggcaaaaaca
    27481 cgctgtgttt tattaagagt atcgattgca tcagtaagtt ggatttcatt tccagcacca
    27541 ggagcttgct tttcgagaat ctcaaaaatt tcaggcgtga ggaggtagcg tccgataata
    27601 gcaaggtcgc taggagcgtc ctctggagct ggtttttcaa caaaggtttc aacactgtaa
    27661 agaccatctt ttccttcgcc ttgcggagca ataaccccgt aagcagatac ttcgtcatga
    27721 gggactggca tgacagcgat agtagacgcg tgggtacgct cgtagtcatc catgagttgt
    27781 ttggtaagtg gaacagtctt ttcgtctgtg atatccatca agtcatcacc cagcataaca
    27841 acaaaaggtt catttccaac gaaagccttg gcttgcaaaa cagcatcgcc gagaccacgt
    27901 ggatgcgttt ggcggataaa atgcaggcgc atgccagttg tttcatcaac tagcttcaga
    27961 agatctgttt tccctttttc tttgagatta tattccaatt caaagtttga atcaaagtgg
    28021 tcctcaatag aacgttttga tttaccagtg acaactagaa tatcttcaat acctgatttg
    28081 agagcttctt ccacgataaa ctggatagtt ggtttgtcta cgattggcaa catttctttg
    28141 gcaagggcct tggttgctgg taaaaatcga gttcctagtc cagcagcagg gatgactgcc
    28201 tttctaactt ttgatgtcat aaaaatcctt tctatagagg gttaagacca ctcattttct
    28261 gctttaaatt cattgttcat gatgtcataa atggcatctt tgatattggt tccgtgataa
    28321 ataacttggt aaatagcctg tgtaatgggc atatagactc caagttcttg ggctagttca
    28381 taggctgctc gagtcgttga aattccttcg attaccatgc ccatattagc ttctatatca
    28441 gctagggatt ctcctcgtcc gagagcatct ccagctctcc agttacgaga gtggatggaa
    28501 gttcccgtta cgatcaaatc tcccacacca gataagccgc tataggtcaa tggactggcc
    28561 ccgagtgcta cccctaggcg ggtgatttct gctaaacctc gagcgatgat ggctgcctta
    28621 gcattatcac caaatccaag accatgtaaa gctccagcac cgacagcaat aatattttta
    28681 agagcaccag cagtttcaac cccgataaca tccgtattgg tataaagtcg gaagtagtga
    28741 ttactaaata gctcctgaac gtattgagct gtttgtaaat ctttagaagc agcagttatt
    28801 aaagttaggt cacgcacaat ggtctcttct gcatgactag gccctgaaac aacgacgata
    28861 tcactacgga gatgttcagg aatttcttct tcaagaatgg ttgataatcg tttatggcta
    28921 tcaggttcta atccctttga tgcgtgcatg atgataacct tatggtccaa ggtttgtgca
    28981 acttgctggg caacaagtcg tgtcactttt gttgggacaa caaacaaaat cgcatccaca
    29041 tttttcaatg tttctgctaa gtcggtgtag gcaatgatat tttcgtctag aacgacatct
    29101 ttaaagtagt gcttattagt atggtgtgta ttaatttcat tgatttgctc gggaagattt
    29161 ccccaaatac gtacctcgtg tccattgtca tttaagactt gtgaaagggc ggttccccaa
    29221 gaaccaggcc ccaagacggc gacggtttgt ttttccatga tttcctcctt gatagatttc
    29281 tttctcttat tctatcatat tctaggggat tttgcacttg cattactggg gtatggtgga
    29341 aaaatacaca aagaccgaga tgaagggata aactcttagt ctttagttaa agtgagaaga
    29401 aatctgatag atagtttgat tcagtatatg cttataatag aggtaaacaa ctcaggaggt
    29461 tcttgtaggt tgcgagagtt tggcgaaaaa attaaaagat tacgtttggc taaaaaaatc
    29521 agtcgttcag aattttgtgg tgatgagtct gaattaagta tccgtcaatt aattagaatt
    29581 gaaaatggag aatccagacc aatactaaca aagttaaaat atattgctga acgtttggag
    29641 gttgaagatt acaagttgat gccaagttat atagagttgg ataaggaata cctagaattg
    29701 aagtatttct tgatgaggac tcctacatac gaagatgaaa ctatcgccca aaagaaagag
    29761 agtgtttttg ctaagatttt tgaagagtat tatgataggc tacctgagga agaaagattt
    29821 atcatcccaa attattcata tctagcacta gcgaactaca cagttcaaaa attaccagaa
    29881 aagctagttg aaatactgtc cttctggtga ttttgcttaa tttctgatgt tagagacata
    29941 attgaggaga tttgtcttga ttttttccta aaaaagggca gactcctccc ttggtttgat
    30001 gctcgatttt taaaataagg tgacttattc tgttaggcat gttttcccct gccctctagc
    30061 tctatatgga acagggagta tcagatttat ctggcagatt gtatcaaata aggcttgaaa
    30121 ctgttttgaa taggcgtata gacttgagaa tttgagaata tgtcgtctag cagtagagac
    30181 atattttccg gcaatatgaa ggaagagacg tcgaaaacgc ttgatagtca aggcctttac
    30241 ttcatcacca gctagctgct ttaaaaagag gtagagatta taagccagac agcccatcat
    30301 catacgtact tcattcttaa tcatggtcga actatctgtc ttatccccaa agaatcctgc
    30361 tttcctttct ttgataaagt tttcagcatt ccctcgttca cgatagaatt gaaacagctc
    30421 ctcactatct acactgctta aattggtcaa atgaactttt ttacaaccat aaaaaagagc
    30481 acttaatcgt actcttctct tttaaggatt agttgaatta attcaaatcc actagttctc
    30541 ctgtttctag gtagactagg cgttcacaaa tgttagcaat gtaatcagcg aagcgttcca
    30601 gatgccctat gatataaagg tattgtgttc cattgggaat tgaggtttct tggtctttca
    30661 taagtccaat gatttccttt gataaggcat aataatattg gtcaatctgt tcatcttttt
    30721 gagcaatact aatagctttt gaggcttggt gcaaaggaaa ggcaaccaat aaatcggata
    30781 gcatgctgag ggataattta cccatttggt gtaactgttc ttcgtcaggg gctagttgat
    30841 tttcttttag ttgcaaaaca gctttagcaa tgcctgccat atggtctccc atacgttcaa
    30901 ggtctgaaca agaagacatg atgctaatca caaatcgaag gtcagacact tgtggctgct
    30961 gcaaggccaa caaacgggca caggtcaatt cgatagcgct ttgaccttgg ttgatagcat
    31021 gatccttatt gataattagc tctgccatct ccttgtcttt ggaggctaag gccagtaagg
    31081 tttttgaagc tgtttcaagg acaagttgcc ctagtcctaa aaaggattgt tctaattcat
    31141 gcaattctaa gtcaaattga tttctcatag gtttttcctt ccttatccga accgtcctga
    31201 aatatagtct tctgtgcgct gatcttttgg attggtaaac acgtcaacgg tgtctccaaa
    31261 ttcgcaaatt tctcctgtta agaaaaaagc agttttatct gaaatacgtg aagcttgttg
    31321 catgttatgg gtaacaatga taatcgtata atcctttttt agttgctgaa tgaggtcttc
    31381 aatttttaaa gtggagatag ggtctaaggc tgaagtcggc tcatccatta acagaacatc
    31441 aggttctact gctaaagctc gcgcaatgca aaggcgttgc tgctgaccgc ctgataagga
    31501 catggcactc tttttaagat tatctttgac ttcgtcccaa atggctgccc cttttaaaga
    31561 tttttccact aaggcatcta attgtttttt gtctcgaata ccatgtgtcc ttgggccata
    31621 agccacgtta tcatagatag acatggcaaa gggattaggc tgttgaaaaa ccatccctac
    31681 acgcttgcgt agctgattaa ggttgaattt gctactataa atatcttgct catctaagag
    31741 gacttggcct tcaatatggc aagaaggaac caaatcgttc atccgattaa gggtttttag
    31801 aaaagttgat ttaccacaac cagatgggcc tatcaaggca gtaatctgtc tttctggtaa
    31861 ttgaatcgaa atatttttta aggcttgaaa atccccgtaa aataagtcta ggtgtctgac
    31921 tgaaaatgtt cccatactag gaagctcctt tcacaagttt tcgagataat aagcttgata
    31981 gagtatttat cattaaaaca gtaataatca aaatcacacc ggtagcatag gcttcattga
    32041 catgtagccc ctcacttgac agcatataca tatgcagggc tagagaacga cctgaagaca
    32101 tgagactact tggcgtattg gtagaggtac ctaatgtata catgagggca gctgtctcac
    32161 caacgatacg gccaatagct agtatcactc cagctaaaat acctggcatg gcaactggta
    32221 gaacaattct aaaaacagtc cgtaacttac ctgccccaag tccataactt gcttgacgca
    32281 tgctatcact aacagataaa agggcttctt ctgttgagcg aataatgact ggcaacacca
    32341 tgatgactga ggttaagatt cctgataaca gagagtattg aaaacctaag aagactacaa
    32401 agaagagcat gccaaacaga ccaaaaacaa tggaaggaat cccagacaag gtatctgagg
    32461 ccaatcgcat aattttaaca caaagggaat ctttttttgt atattccaca agataaaaac
    32521 cagcaaaaat ccctatgggc aaggctaaaa gaagagcacc aaaaaccaga ataacggtgg
    32581 aaataatcgc tggcataagg gaaatgttct cagaagtata agtccaagaa aagagggata
    32641 gacttagatg aggtaagcct ttgatgagga taaaaccaat gattaaaaag agagagccaa
    32701 aggttaaagc tgaaaaacaa taaacgagaa gttttagcag gtatttactc ataagatgat
    32761 tttcctttca agtaggcaaa gtaggcatta atcaagagaa taaggaaaaa gagaactgct
    32821 gaggttgcaa taagggcttc cctatgctga cctgatgcgt aagccatttc cagaacaata
    32881 ttggttgtta aggttctggt tcctgaaaag agtccacttg gaataatcgg ctggttgcct
    32941 gccaccaaaa taactgccat ggtttcacct actgcgcgac cgattcctaa aataactgct
    33001 gataaaatac cagatctcgc agctggcaag atgacactaa aaatactccg ttcatgacta
    33061 gctcctagag ccaagctacc agaataatac gttttgggaa ctgttcggat agcagattct
    33121 gacaaactga taatggttgg caaaatcatt attcctaata gtaacgaagc ggttaggaca
    33181 ctcatgccat ttcctaaaaa ggttctaatc caaggcacca ataattgtag gccgaaaaaa
    33241 ccataaacaa tagatggaat ggccgccatc aagttgatag ctgattttaa gaagccatag
    33301 acgggctttg gacaataata aaccataaac accgatgtca agatgcctgt tggcacccca
    33361 atcacaatcg ctcctaaggt aattaataag gaaccaacga tcattggtaa aataccatag
    33421 cttgccggaa tgttcgttgg cgaccaatca ctgcctaata aaaaacgggc aaagccgtag
    33481 ttagccatga aaggtaagcc attactaaaa ataaagaaac agattagcaa aatagctaca
    33541 acagctactg ttgcactcat gaaaaaaatt gccctaaaaa ctgcttcttt gaaggcttgt
    33601 tttatcacat cttgtccttt ctagtgaaga aagtaaggga gatacgacac ctccctactt
    33661 gccttcttta tcttattgta cgatgaaacg tctgcatctc tttagagatt tatggagcaa
    33721 acattttatt taatcttgtc ccaggtggtt aatttgccac taaaaacgtc tgcaagttca
    33781 gccatactga cttggcttgc cttattgtca ttattgacca caacagcaat accgtctaaa
    33841 gcaatagcat catgggtgag actcttacct tcttcaggag ttaattccct agaaaccata
    33901 ccaatatcag cggttttctc cttaacagcg gtaatacctg ctgaagatcc attagaggta
    33961 atatcaatcg taacttctgg attttctttt ttataagctt ctgctaattt ttccattaaa
    34021 gaagatactg aagtggaacc tacaacagac aacttgcctg ataagtgttg gcttgtatat
    34081 tctgtggttt cggttttagc ttcaataaat ttattatctg tgaccacttg ttgaccttgt
    34141 ttggagtgga taaagctgat aaaatcttga cctagcttgg aaagattaga agaccaaaca
    34201 atgttgaagg gacgttgaag agggtattca ccatctaaaa ctgtgtctcg actagccttg
    34261 acaccatcaa tctctaaagc cttgacagat ttcgttaaag atcccaagga gatgtagccg
    34321 atagcattag cattcccttg aactgctgag agaacacctt ctgtactatt ttgaatcaca
    34381 gctgttttgg tagtgttgtc aattttttta tcaccgtctt ttttgagaat ccctgtgatt
    34441 tctgtgaagg caccccgtgt tccagagcca ttttctcgtg aaatcacctc aatcgttcct
    34501 gaagctgact gtttggaagc agctgactga ttgccacagg caacaagccc aaatcctgat
    34561 aagccaatgg ctgcaagagt aagcattttt ttgaatttca taataatcac ctttatctct
    34621 atgtattttt cttgtgtagg cttactacat ttatagtcta acaagtcttt gtaaaggttt
    34681 atccctgatt catgtaaaga ttgtgtaaag aatcaaaaaa agccactttt gaaaaatggc
    34741 tgctcctaaa aatagcttta aaaattatta gtcctgtgcg aaagattggt taggaagaaa
    34801 aatcgtgaag caactgcctc tgccaagctg actcgtcacc gtgacttggc cacctaataa
    34861 ttgactgagt tctttgacaa tggcaaggcc aagaccagtg ccaccagttt gtctgcttcg
    34921 acctttatta actcggtaaa aacgttcaaa aatacgatcc tgctctaatt gactaatacc
    34981 aatccctgta tctgatacag aaatcttaat gccttcgttc accttttggg tcttgacctc
    35041 aatttttccc ccttgttcag tgtaacggat ggcattggat aaaagattga gtaagatttg
    35101 ggaaagtaat tgactatctg atacgagggt gacatcatct ggcacctgca cctttagctg
    35161 taaatccttc ttcttgagct gaggttgcaa gctttgagtc aaatcctgta caaattctgc
    35221 caaagaaagg gtcgtccatt gtataggcat ttgttgagcc ttagataagg taagaagatg
    35281 ctcaacaata tgctcaagac gcaaactttc tttgtaaata atgtctagaa agtcatcctt
    35341 gagcgcttct tcttcagctg acatcccctt aatggtttca gcaaagccct taatcgaagt
    35401 aactggtgtc ctcaattcat gggaggcatt tgagacaaag gctaaattta acttttcata
    35461 agttctaatc gttgttaaat catatagcaa gacgagcaca gcttccacag attgggtggg
    35521 gctaaaaacg ggaactgctg tcacttctaa aatcaagtca ccctcatgaa acccacttac
    35581 ttcttgtttt aaccttgttt tttgatcaaa ggcttggtga actaaattcc gaatatccat
    35641 ccgtttgagg tcatcaagtg aacttatgtc gccgtccaca tcgggaaaat aatgaggcag
    35701 agagcgactg gataataaca tctgaccttg agcggaaact aaaaacgtcc ccatggttag
    35761 gtgcgacaga agaacctcca ttgtttcggc tagatccttg tattgctgat cctgttggga
    35821 gactttggtt tttaggccag acacatactg agccaaagac tttaagtctt cttgcccttt
    35881 ttctaaaaag tattcactac tggtcaagag aggttggtgc aaggtctcaa aagcaacttc
    35941 ccatttccaa aggcaaaaga gccagtagcc acctagtccc aaagaaaggg ctagaagaaa
    36001 gagaccgatg cctttactga tccaagttaa tgccatccct gcaatcagaa tgaggctaac
    36061 acttagattg actagccaaa attgaaggta gcgtttcatc tataactcct tgaacttata
    36121 accatacccc cgaatggttc gaataaattg aggggcttta ggattgtctt caattttttc
    36181 ccttaactta ccaatatgaa cgtccaccaa acgtgtttcc tgcccaaagt cataccccca
    36241 gatacgttcc aaaagacgct ctctagtcag tgtcatgttg ggatgtttca taagatagag
    36301 caagagttca aattcttttg gggtcaaact cagtaactta ttcgccttgt agacttcatg
    36361 acgctcaggg tatactttca aggtcccaaa tagccaagaa tcgtcagcga tattatctga
    36421 atcatctcct tcttgttctc ctttagttcg cctgaggaca gccttgacac gcgccagcaa
    36481 ttctctaggg ctaaaaggct tggtcaggta gtcatcagcc cctaattcca aggccaaaac
    36541 cttatcaaat tcatcacttt tcgcagaaac catcataatt ggagttttga cgcctttggc
    36601 tctcagccgc ttacaaactt ccatgccatc taattgtggt aacatgatat caagcaagat
    36661 aaaatcaaag ggttctgttt ctgccaaagc taaggccttc cgtccatttg ttaccaattg
    36721 agtagaaaag ccttccttac ttaaatggta gtcaagcaat ttcagaatgt gttcttcatc
    36781 atccactaat aagacttgtt ttgtcatcta ttatctccta ttggtaacat tataacacaa
    36841 ttatcagaaa tcctaacatt gctaaatcag attaaatttg cttatcaaga ctagtatctg
    36901 gtcaaacgct caatcatctc cttgtgctct ggataggtcg ccagtagatc taccctttca
    36961 aataattcaa aatcctcaaa ttcaaaacca ggagcaacaa gacaagaaac cagagcatca
    37021 tccttatcaa ctgttgatcc ccaaatagtg cccttaggaa cacagtagtg aagttgttgc
    37081 cctttggata tgtccaggcc taaagtgact gcttcgtagt gaccatctgc tgtaatcatg
    37141 tgaacagtaa gtggggattc tgcatgaaaa taccagattt catctgctgt caatcggtga
    37201 aaatgtgaag gattcgtttc ttcttaataa gaaataaata ctggtataaa gcgcccttcc
    37261 cttaccagca aggtttatag tgtctgaagc tttttttgtt tgtctaaaat agccaccttc
    37321 aacatgggga gctaactcta gagttcttat caagtcttct ttatccgtcg gagccaatgg
    37381 gttgaagtaa ctcttgttca aagtggtgtt acgatttcaa gaactcctct cagttctgag
    37441 gacacggtaa tgattgatgc gacggaagta caaatcaatc gccctaaaag aagaattagc
    37501 gaatgattct ggtaaaaaaa atgccacgct atgaaggctc aagcgattgt cacaagtcaa
    37561 gggagaattg tttctttgga tatcgctgtg aactattgtc atgatatgaa gttgttcaaa
    37621 atgagtcgca gaaatatcgg acaagctggt aaaatcttgg ctgacagtgg ttatcaaggg
    37681 ctcatgaaga tatatcctca agcacaaact ccacgtaaat ccagcaaact caagccacta
    37741 acagttgaag ataaagccta taaccatgcg ctatccaagg agagaagcaa ggttgagaac
    37801 atctttgcca aagtaaaaac gtttaaaatg ttttcaacaa cctatcgaaa tcatcgtaaa
    37861 cgcttcggat tacgaatgaa tttgattgct ggtattatca atcatgaact aggattctag
    37921 ttttgcagga agtctattat ttggttaggt gaattagtga agtgtttagg caagtgtctc
    37981 tggttacgac gtcatggcct ctaaatcgat tatatttagg ggtcatgact agtgaagcag
    38041 ttagctagtt cgcatataag cggctagcgt ctaacaatta ggaactttag ttccaataac
    38101 tttaagatta cgacgtttta ggacataaat cgatcatatt tatgtcctaa aactagtgaa
    38161 gcgcctagcc aaagtccgaa taggatttgg cgttagttac ttagattgct ttgcaatcaa
    38221 gtaactttgg cgatttacat cttctctggc gcttctactc caagcaagcg aagggcttct
    38281 ttgagaacga ctgcggttgc gtagctgagg gctagacggc tgtcgcgttc tgggctttca
    38341 tccaagatac gtgtatgtgc atagtatttg ttaaaggatt gagccaggct aattgcaaat
    38401 ttagcaatga tagaaggttc aaagttatct gccgcacggt tgataatacg tgggaagtct
    38461 tgaatgagtt taatgatttc ccagctttca gtatcattca agctatagtt gccagctgtt
    38521 tctggtttga aatcggcttt gcgtaagata gattggatac gagcgtaggc atattgaacg
    38581 taaggtccag tttcaccctc gaaggatacc atagcttcta ggtcgaagtc gtatccattt
    38641 gtacggtcgg ttttgaggtc atagaattta atggctccaa ccccaacagc atgtgctact
    38701 tggtctttgt tttctagttc aggattttta gcctcgattt ggaccttggc acggctaaca
    38761 gcctctgcaa cagtaggctc tagcaagatg acattccctt tacgagtaga gagtttcttc
    38821 ccttcttttg taaccaaacc aaaaggaacg tgagtaatgt cgtcactcca gtcgtagccc
    38881 atctcttgca agacagcttt gagctgttta aagtgggcag attgttcttg accaacgaca
    38941 tagatagatt tagcaaattg gtattcgttt ttacggtaaa gggctgcagc caagtcacgt
    39001 gtgatataga gagttgcacc atcagatttc ttgatgaggg ctggatgttc aattccgtat
    39061 ttctcaagat tgacaacttg ggcaccttct gattcaagaa gtagtccttt ttcagaaaga
    39121 atgtctacaa ctgcatccat cttatcattg tagaaggctt ctccgttata gctgtcaaat
    39181 tcaaccttca attcattgta aaggcggtta aattccacta aactttcatc gcggaaccat
    39241 tgccaaagag cgagagcttc ctcatctcca ttttcaagtt tacggaacca ttcgcgcgct
    39301 tcttcatcca agctagggtc attttcagct tcagcgttga tgcggacata gagtttaagg
    39361 agttcatcga ttggatgagc ttttacagct tcttcgtcgc cccatttttt gtaggcaaca
    39421 atcaacatcc caaattgttt accccagtct cccaaatggt tgaccttgac cgtttgataa
    39481 ccgatttttt ggaaaatatg tgacaagcta tctccgataa cagttgaacg caggtggcca
    39541 atagaaaatg gtttagcgat attcggacta gacatgtcga taacaacatt ttcttgtttg
    39601 ccaatatttt ggtcagcata gtgttctttt tcagtggtaa cagcttgcaa tacttgagca
    39661 gaaatggcag atttatcaag gaaaaagtta acgtaaggtc ctgttgcgac aactttttca
    39721 aaggcttggc tgttcatttt ttcagccagt tcagccgcaa tcatttgtgg tgctttacgt
    39781 tcgacttttg caagagaaaa agcagggaaa gcaatgtctc ccatttctga gtttttaggg
    39841 gtttccagta actttaaaat agcctcttgg tccaggctat caatgatgct agataattcg
    39901 ctagcaatca attcttttgt attcattaag agctcctttt tggacttttc tactatttta
    39961 tcacaatttt aaagaaagaa gaaaaaattt ttgaaatctc ctgttttttt ggtataatat
    40021 ggttataaat atagttataa atatgcacgc aagaggattt tatgagaaaa agagatcgtc
    40081 atcagttaat aaaaaaaatg attactgagg agaaattaag tacacaaaaa gaaattcaag
    40141 atcggttgga ggcgcacaat gtttgtgtga cgcagacaac cttgtctcgt gatttgcgcg
    40201 aaatcggctt gaccaaggtc aagaaaaatg atatggtgta ttatgtacta gtaaatgaga
    40261 cagaaaagat tgatttggtg gaatttttgt ctcatcattt agaaggtgtt gcaagagcag
    40321 agtttacctt ggtgcttcat accaaattgg gagaagcctc tgttttggca aatattgtag
    40381 atgtaaacaa ggatgaatgg attttaggaa cagttgctgg tgccaatacc ttattggtta
    40441 tttgtcgaga tcagcacgtt gccaaactca tggaagatcg tttgctagat ttgatgaaag
    40501 ataagtaagg tcttgggagt tgctctcaag acttattttt gaaaaggaga gacagaaaat
    40561 ggcgatagaa aagctatcac ccggcatgca acagtatgtg gatattaaaa agcaatatcc
    40621 agatgctttt ttgctctttc ggatgggtga tttttatgaa ttattttatg aggatgcggt
    40681 caatgctgcg cagattctgg aaatttcctt aacgagtcgc aacaagaatg ccgacaatcc
    40741 gatccctatg gcgggtgttc cctatcattc tgcccaacag tatatcgatg tcttgattga
    40801 gcagggttat aaggtggcta tcgcagagca gatggaaaat cctaaacaag cagttggggt
    40861 tgttaaacga gaggttgttc aggtcattac gccagggaca gtggtcgata gcagtaagcc
    40921 ggacagtcag aataattttt tggttgccat agaccgcgaa ggcaatcaat ttggcctagc
    40981 ttatatggat ttggtgacgg gtgactttta tgtgacaggt cttttggatt tcacgctggt
    41041 ttgtggggaa atccgtaacc tcaaggctcg agaagtggtg ttgggttatg acttgtctga
    41101 ggaagaagaa caaatcctca gccgccagat gaatctggta ctctcttatg aaaaagaaag
    41161 ctttgaagac cttcatttat tggatttgcg attggcaacg gtggagcaaa cggcatctag
    41221 taagctgctc cagtatgttc atcggactca gatgagggaa ttgaaccacc tcaaacctgt
    41281 tatccgatac gaaattaagg atttcttgca gatggattat gcgaccaagg ctagtctgga
    41341 tttggttgag aatgctcgct caggtaagaa acaaggcagt cttttctggc ttttggatga
    41401 aaccaaaacg gctatgggga tgcgtctctt gcgttcttgg attcatcgcc ccttgattga
    41461 taaggaacga atcgtccaac gtcaagaagt agtgcaggtc tttctcgacc atttctttga
    41521 gcgtagtgac ttgacagaca gtctcaaggg tgtttatgac attgagcgct tggctagtcg
    41581 tgtttctttt ggcaaaacca atccaaagga tctcttgcag ttggcgacta ccttgtctag
    41641 tgtgccacgg attcgtgcga ttttagaagg gatggagcaa cctactctag cctatctcat
    41701 cgcacaactg gatgcaatcc ctgagttgga gagtttgatt agcgcagcga ttgctcctga
    41761 agctcctcat gtgattacag atgggggaat tatccggact ggatttgatg agactttaga
    41821 caagtatcgt tgcgttctca gagaagggac tagctggatt gctgagattg aggctaagga
    41881 gcgagaaaac tctggtatca gcacgctcaa gattgactac aataaaaagg atggctacta
    41941 ttttcatgtg accaattcgc aactaggaaa tgtgccagcc cactttttcc gcaaggcgac
    42001 gctgaaaaac tcagaacgct ttggaaccga agaattagcc cgtatcgagg gagatatgct
    42061 tgaggcgcgt gagaagtcag ccaacctcga atacgaaata tttatgcgca ttcgtgaaga
    42121 ggtcggcaag tacatccagc gtttacaagc tctagcccaa ggaattgcga cggttgatgt
    42181 cttacagagt ctggcggttg tggctgaaac ccagcatttg attcgacctg agtttggtga
    42241 cgattcacaa attgatatcc ggaaagggcg ccatgctgtc gttgaaaagg ttatgggggc
    42301 tcagacctat attccaaata cgattcagat ggcagaagat accagtattc aactgattac
    42361 agggccaaac atgagtggga agtctaccta tatgcgtcag ttagccatga cggcggttat
    42421 ggcccagctg ggttcctatg ttcctgctga aagcgcccat ttaccgattt ttgatgcgat
    42481 ttttacccgt atcggagcag cagatgactt ggtttcgggt cagtcgacct ttatggtgga
    42541 gatgatggag gccaataatg ccatttcgca tgcgaccaag aactctctca ttctctttga
    42601 tgaattggga cgtggaactg caacttatga cgggatggct cttgctcagt ccatcatcga
    42661 atatatccat gagcacatcg gagctaagac cctctttgcg acccactacc atgagttgac
    42721 tagtctggag tctagtttac aacacttggt caatgtccac gtggcaactc tggagcagga
    42781 tgggcaggtt accttccttc acaagattga accgggacca gctgataaat cctacggtat
    42841 ccatgttgcc aagattgctg gcttgccagc agacctttta gcaagggcgg ataagatttt
    42901 gactcagcta gagaatcaag gaacagagag tcctcctccc atgagacaaa ctagtgctgt
    42961 cactgaacag atttcactct ttgatagggc agaagagcat cctatcctag cagaattagc
    43021 taaactggat gtgtataata tgacacctat gcaggttatg aatgtcttag tagagttaaa
    43081 acagaaacta taaaaccaag actcactagt taatctagct gtatcaagga gacttctttg
    43141 acaattctcc acttttttgc tagaataaca tcacacaaac agaatgaaaa ggagctgacg
    43201 cattgtcgct cccttttgtc tattttttaa ggagaaagta tgctgattca gaaaataaaa
    43261 acctacaagt ggcaggccct ggcttcgctc ctgatgacag gcttgatggt tgctagttca
    43321 cttctgcaac cgcgttatct gcaggaagtc ttaggcgccc tccttactgg gaaatatgaa
    43381 gctatttata gtatcggggc ttggttgatt ggtgtggccg tagtcggtct agttgctggt
    43441 ggactcaatg ttgtcctcgc agcctatatt gcccaaggag tttcatccga ccttcgggag
    43501 gatgccttcc gtaaaattca aaccttttct tatgctgata ttgaacaatt taatgcggga
    43561 aatctagtcg ttcgaatgac aaatgatatc aaccagattc agaacgttgt catgatgacc
    43621 ttccaaattc ttttcagact tcccctcttg ttcatcggtt cgtttatcct agcggttcaa
    43681 accttacctt ctctgtggtg ggtgattgtt ctcatggtag tcttgatttt tggtttgact
    43741 gctgtcatga tgggaatgat ggggcctcgt tttgccaagt ttcaaaccct tcttgagcgc
    43801 atcaatgcca ttgccaagga aaatttacgt ggcgttcgtg tggtcaagtc ctttgtccaa
    43861 gaaaaagagc aatttgctaa gtttacagag gtctcagacg agcttcttgg tcaaaacctt
    43921 tacattggtt atgccttttc agtagtggaa ccctttatga tgttggttgg ttacggggcg
    43981 gtcttcctct ctatttggct ggtcgcggga atggttcagt cggatccgtc tgttgttggt
    44041 tccatcgctt cttttgttaa ttacctaagc cagattatct ttaccattgt tatggttgga
    44101 tttttgggaa attctgtcag ccgtgccatg atttccatgc gtcgtattcg agaaattctt
    44161 gacgcagagc cagctatgac cttcaaggat atcccagatg aagagttggt tggaagcctt
    44221 agctttgaaa atgtgacctt tacctatcca atggacaagg aaccgatgct gaaagatgtg
    44281 agctttacta ttgaacctgg tcaaatggtt ggtgtagttg gagcgactgg tgcaggaaag
    44341 tcaaccttgg ctcaattgat tccacgtctc tttgatccac aggaaggggc tatcaaaatc
    44401 ggaggtaagg atattcgaga agtgagtgaa gggaccctgc gtaaaacagt ttccatcgtt
    44461 ctccaacgtg ccattctttt tagtggaacg attgcagata acttgagaca ggggaaggga
    44521 aatgctactc tatttgaaat ggagcgcgca gccaatattg cccaggctag tgaattcatt
    44581 catcgtatgg agaaaacctt tgaaagtcca gttgaagaac ggggaaccaa tttctctggt
    44641 ggacaaaaac aaaggatgtc gattgcgcgt gggattgtca gcaatccacg tattctgatt
    44701 tttgatgatt cgacctcagc cttggatgcc aaatcagagc gcttggtgca agaagctttg
    44761 aataaggact tgaaggggac gacaactatt attattgctc aaaaaattag ctcggttgtc
    44821 catgcagaca agatcttggt tctaaatcaa ggacgattga ttggtcaagg cacgcatgca
    44881 gacttggttg ccaacaatgc cgtttaccgt gaaatctatg aaacacagaa atgaaagaca
    44941 aactataaga aaagtcaata gttttatcta aactatttct tatttcaatt tgatgatttg
    45001 gcgatgattt tagagcacgg caaaaagccc ttgaaaaagt ccattttttc aaaggtaatc
    45061 ctgtgttaat ttcagaaatt acatcacttt ttgttcgtca aatggcagct cttttttagg
    45121 atataaaaca gggttcggat aagttttttt gcaaggtgga tgatggctac attgtaatgt
    45181 tttccttgtt ctaacttagt cttaagatag gtcttaaaag caggtgaaaa gcgagggcat
    45241 gctttggcag cttgtatgag tacctaccgc agatgagggg aaccccgttt gaccattctt
    45301 ccagctaaat caatctgacc tgactgataa atagaagaat ccagtccagc gaaagcttgt
    45361 aattgagcag gattatcaaa ggcatgaata tttcgaatct cggctaaaat gaccgcccct
    45421 aaacgattct caatcccagt aaccgtcgtg atgaccgagt tgaactcagc catcaagtca
    45481 ttgacacatg tttccgcctt gtcaatgagc ctcttgtaat gtttgatgtt ttcattacac
    45541 gagataaaac gtctatgcgt tatcaaactc attaccaatt aaaacaaaaa gctgtggtta
    45601 gatcctttcg gaaattgtca agcgattgga ggaaatgaac taatccacag cggcttattc
    45661 caagtatacc acttgggctt tggcagtagc taactgcgct aaatataata taaggaggag
    45721 taaaatgaag acagttcaat ttttttggca ttattttaag gtctacaagt tctcatttgt
    45781 agttgtcatc ctgatgattg ttctggcgac ttttgcccaa gccctctttc cagtcttttc
    45841 tggacaagcg gtgacgcagc tagccaattt agttcaagct tatcaaaatg gcaatccaga
    45901 acttgtatgg caaagcctat caggaatcat ggtcaatctt ggcctgctgg ttttggttct
    45961 atttatctct agtgtaatat acatgtgtct catgacgcgc gtgattgcag aatcgaccaa
    46021 cgagatgcgc aaaggcctct ttggtaagct tgctcagttg acggtttctt tctttgaccg
    46081 tcgacaagat ggcgatatcc tgtctcattt taccagtgat ttggataata tcctccaagc
    46141 ctttaacgaa agcttgattc aggtcatgag caatattgtt ttatacattg gtctgattct
    46201 tgtcatgttt tcgagaaatg tgacgctggc tctcatcacc attgccagca ccccattggc
    46261 tttccttatg ctgattttca tcgtgaaaat ggcacgcaaa tacaccaacc tccagcagaa
    46321 agaggtaggg aagctcaacg cctatatgga tgagagcatc tcaggccaaa aagccgtgat
    46381 tgtgcaagga attcaagagg atatgatggc aggatttctt gaacaaaatg agcgcgtgcg
    46441 caaggcaacc tttaaaggaa gaatgttctc aggaattctt ttccctgtca tgaatgggat
    46501 gagcctgatt aatacagcca tcgtcatctt tgctggttcg gctgtacttt tgaatgataa
    46561 gtctattgaa acaagtacag ccctaggttt gattgttatg tttgcacaat tttcacagca
    46621 gtactaccag cctattatcc aagttgcagc gagttgggga agccttcagt tggcctttac
    46681 tggagctgaa cgaattcagg aaatgtttga tgcagaggag gaaatccgac ctgaaaaggc
    46741 tccaaccttc actaagttgc aagaaagtgt tgaaatcagt catatcgatt tttcatactt
    46801 gcctgataaa cctattttga aagatgtcag catttctgcc cctaaaggcc agatgacagc
    46861 agttgttggg ccgacaggtt caggaaaaac gactattatg aacctcatca atcgctttta
    46921 tgatgttgat gctggtggta tttattttga tggtaaagac attcgtggct atgacttaga
    46981 tagtcttaga agcaaggtgg gaattgtatt gcaagattcg gtcttgttta gcggaacgat
    47041 tagagacaat atccgatttg gtgtgccaga tgctagtcag gaaatggttg aggtagcagc
    47101 aaaagcaacc cacattcacg actatatcga aagtttgcct gataagtacg atactcttat
    47161 tgatgatgac cagagcatct tttcaacagg gcagaagcaa ttgatttcaa tcgctcgaac
    47221 cctgatgaca gatccagaag ttctcattct cgatgaagca acttcaaacg tagatacggt
    47281 gacagaaagc aagattcagc atgccatgga ggtggttgta gcaggtagaa ctagtttcgt
    47341 cattgcccac cgcttgaaaa ccattctcaa tgcagatcag attattgtcc ttaaagatgg
    47401 agaagtcatt gaacgtggta accaccatga acttttgaag ctaggtggct tttattcaga
    47461 actctatcac aatcaatttg ttttcgaata agaaagaagt tgtcctatgt gggcagcttt
    47521 ttcttgtcca taaaaaatgt ttatcacagc cttaaaaaaa acatattaga cgaaagtcat
    47581 tttgagtgat atgataggac tatcgttagc attcgaaagg agaggcatca tggctagaac
    47641 ggttgtagga gttgctgcaa atctatgtcc cgtagacgca gaaggcaaaa tcattcattc
    47701 atctgtatct tgtagattcg cagagatcat tcgtcaagtc ggtggtctcc ctttagtcat
    47761 tcctgttggt gatgagtcag ttgtacgtga ttatgtggaa atgattgaca aactcatttt
    47821 gacaggaggc caaaatgttc atcctcagtt ttatggagag aaaaagaccg tcgaaagcga
    47881 tgattacaat ctggtccgtg acgaatttga attggcactc ttgaaggaag cgcttcgtca
    47941 gaataaacca attatggcaa tctgtcgcgg tgtccaactt gtcaatgttg cctttggtgg
    48001 aaccctcaat caagaaatcg aaggtcactg gcaaggacta cctttcggga catctcactc
    48061 tattgagaca gtagaaggaa gcgtggtggc taagctattt gggaaagaaa gtcaggtcaa
    48121 ctcagtccat cgtcaaagca ttaaagattt ggcacctaat ttccgtgtaa ctgctattga
    48181 ttcaagagac caaactattg aagcgattga gtctatcgac gagcaccgca ttatcggttt
    48241 acagtggcat ccagagtttc tggttaatga agaagatggc aatttagaat tatttgagta
    48301 tttattgaat gaactgtaac gattggaaca tctggtcgtt ctttctttta ttttttcaaa
    48361 atttttagaa tgtggcattt tacgcaaacg tttgaattct gataaaaatt ggagaaattc
    48421 gacaaaaaaa cttgaaaaaa acgaaggtaa gcgttatgat agaaaagaag aaatattgga
    48481 ggaagaacat gtcacatatt aaatttgatt attcaaaagt tttagacaaa tttgttgcac
    48541 cacatgaagt ggaatacatg caatcacaag taacagcagc agatgaattg atccgtaaag
    48601 gaactggtgc tggtagcgac ttcttgggat ggttggacct tcctgaaaaa tacgaccgcg
    48661 aagaatttga ccgcatcttg aaagctgctg agcaaatcaa gtcagacagc gatgttttgg
    48721 ttgtgatcgg tattggtgga tcttaccttg gtgcaaaagc agcaatcgac ttcttgaatc
    48781 accattttgc taacttgcaa acaaaagaag aacgcaaagc tccacaaatc ctttacgcag
    48841 gaaactcaat ctcatctact taccttgctg acttggtaga gtatgttgca gacaaggact
    48901 tctcagtaaa cgtaatttct aaatcaggta caacaactga accagcgatt gctttccgtg
    48961 tctttaaaga actcttggtt aagaaatacg gtcaagaaga agctaacaaa cgtatctatg
    49021 caacaactga ccgccaaaag ggtgctgtta aggttgaagc agacgctaac ggttggggaa
    49081 catttgttgt tccagatgat atcggcggac gcttctcagt attgacagcc gttggtttgc
    49141 ttccaatcgc agcatcagga gctgacatca aagctcttat ggaaggtgcg aatgcagctc
    49201 gcaaagacta cacttcagac aaaatctctg aaaacgaagc ttaccaatac gcagccgttc
    49261 gtaacatcct ttatcgtaaa ggctatgcaa ctgagatctt ggtaaactat gagccatcac
    49321 ttcaatactt ctcagaatgg tggaaacaat tggctggtga atcagaagga aaagaccaaa
    49381 aaggtatcta cccaacttca gccaacttct caactgactt gcactcactt ggtcaattta
    49441 tccaagaagg aactcgtatc atgtttgaaa cagttgtccg tgttgacaaa cctcgtaaaa
    49501 acgtgcttat tcctactttg gaagaagacc ttgacggact tggttacctt caaggaaaag
    49561 acgttgactt tgtaaacaaa aaagcaactg acggtgttct tcttgcccac acagatggtg
    49621 atgtaccaaa catgtatgtg actcttccag agcaagacgc tttcactctt ggttacacta
    49681 tctacttctt cgaattggca attgcccttt caggttactt gaatgctatc aacccatttg
    49741 accaaccagg tgttgaagct tataaacgta acatgtttgc ccttcttgga aaaccaggat
    49801 ttgaagaatt gagcaaagaa cttaacgcac gtctataata gaagaaaaga gtggtttgcc
    49861 cactcttttt actctcttta tccatagaaa ttggactcag ccaagacttg tgatataata
    49921 tagaaagcaa aaaggcagac gcctagataa taggagaaac tatgtcaaaa gatatccgcg
    49981 tacgttacgc accaagtcca acaggactac tacacatcgg aaatgctcgt acagcattgt
    50041 ttaattactt gtatgcgcgc catcatggtg gaacatttct catccgtatc gaagatactg
    50101 accgtaaacg ccatgtcgag gatggtgaac gttcacaact tgaaaacctt cgctggttag
    50161 gcatggattg ggatgaaagt ccagaatcat atgagaatta tcgccagtct gagcgtttag
    50221 acttgtatca aaaatacatt gaccaactat tagctgaagg aaaagcctat aaatcttacg
    50281 ttacagaaga agagttggca gctgaacgcg aacgccaaga agtagctggc gaaacaccac
    50341 gctacatcaa tgaatacctt ggtatgagtg aagaagaaaa agcagcttac atcgcagaac
    50401 gtgaagcagc agggatcatc ccaactgttc gtttggctgt caatgagtca ggtatctaca
    50461 agtggcatga tatggtcaaa ggcgatatcg aatttgaagg tggcaatatc ggtggtgact
    50521 ggattatcca aaagaaagac ggttacccaa cttacaactt tgccgttgcc atcgatgacc
    50581 atgatatgca aatctcccat gttatccgtg gagacgacca tattgctaac acaccaaaac
    50641 agctcatggt ttatgaagca cttggttggg aagctccaga gtttggtcac atgaccttga
    50701 ttatcaactc tgagactggt aagaagttat ctaaacgtga tactaataca cttcaattta
    50761 tcgaagatta ccgaaagaaa ggttaccttc cagaagcagt ctttaatttt attgctcttc
    50821 ttggttggaa cccaggtggt gaagatgaga ttttctctcg tgaagaactc attaaacttt
    50881 ttgatgaaaa ccgcctcagc aagtcaccag cagcctttga tcagaaaaaa ttagactgga
    50941 tgagcaatga ttatatcaag aatgcagacc ttgaaaccat ctttgaaatg gcaaaaccat
    51001 tcttagagga agcaggccgt ttgactgaca aggctgaaaa attagttgag ctctataaac
    51061 cacaaatgaa atcagtagat gagattatcc cattgacaga tcttttcttc tcagatttcc
    51121 cagaattgac agaagcagag cgcgaagtca tgacgggtga aacagttcca acagttcttg
    51181 aagcattcaa agcaaaactt gaagcgatga cagatgatga atttgtgaca gaaaatatct
    51241 tcccacaaat taaagcagtc caaaaagaaa caggtattaa agggaaaaat cttttcatgc
    51301 ctattcgtat cgcagtttca ggcgaaatgc atgggccaga attaccagat acaattttct
    51361 tgcttggacg tgaaaaatca attcagcata tcgaaaacat tctaaaagaa atctctaaat
    51421 aaagaggata caataatgga catctgggaa aagatgtacg aagaagcaca gaaactatac
    51481 aatccacatg aagtatcaga ctttgtttat gccaatcatg ttgtagctgc agtagaagca
    51541 ggagatggac aaatatttac aggattctgt atggagggaa cctgtggtgt tttccatctc
    51601 tgcgcagaac gggcggccct cttcaatatg taccaatttt caggacaaac taaggttaag
    51661 aaagtattag cctttcgaga taaaccacct tatggtggaa gttcagccat gccttgcggt
    51721 gcttgtagag aattcctttt agagcttaat gctgaaaata aagatgcaga attcatgatg
    51781 gactataata taagaaaaac agttaaagtc tcagaactaa tcccttattg gtggggagaa
    51841 gaacgtgctt ctaagtttaa tgagcgatag aagagtcagt ataattctgg ctctttttac
    51901 tataaattga aaaaataaaa aaaattagaa aaagtagttg acaaagtttg aaaaggctgt
    51961 ataatagtaa gagttgaaaa taacaactca ggtccgttgg tcaaggggtt aagacaccgc
    52021 ctttt
//
LOCUS       DBEJZV010000015        50091 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.15, whole genome shotgun sequence.
ACCESSION   DBEJZV010000015 DBEJZV010000000
VERSION     DBEJZV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 50091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50091
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.15"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            189..392
                     /locus_tag="ACL3S0_001042"
     CDS             189..392
                     /locus_tag="ACL3S0_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311971.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(479..1066)
                     /locus_tag="ACL3S0_001043"
     CDS             complement(479..1066)
                     /locus_tag="ACL3S0_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311972.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            1220..1417
                     /locus_tag="ACL3S0_001044"
     CDS             1220..1417
                     /locus_tag="ACL3S0_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1311973.1"
                     /translation="MLNAKIFYIFLCLIVIETTGLLLLKRGLEMGYLDTEAIILAVFS
                     FAFYNLCSFAWVCSTIKNNKK"
     gene            2178..3455
                     /gene="ltrA"
                     /locus_tag="ACL3S0_001045"
                     /pseudo
     CDS             2178..3455
                     /gene="ltrA"
                     /locus_tag="ACL3S0_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            3907..5084
                     /locus_tag="ACL3S0_001046"
                     /pseudo
     CDS             3907..5084
                     /locus_tag="ACL3S0_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ryptide export MFS transporter"
     gene            5398..5529
                     /locus_tag="ACL3S0_001047"
     CDS             5398..5529
                     /locus_tag="ACL3S0_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGR1311974.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            5550..7100
                     /gene="dltA"
                     /locus_tag="ACL3S0_001048"
     CDS             5550..7100
                     /gene="dltA"
                     /locus_tag="ACL3S0_001048"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGR1311975.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIAQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            7097..8341
                     /gene="dltB"
                     /locus_tag="ACL3S0_001049"
     CDS             7097..8341
                     /gene="dltB"
                     /locus_tag="ACL3S0_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGR1311976.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            8355..8594
                     /gene="dltC"
                     /locus_tag="ACL3S0_001050"
     CDS             8355..8594
                     /gene="dltC"
                     /locus_tag="ACL3S0_001050"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGR1311977.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            8587..9855
                     /gene="dltD"
                     /locus_tag="ACL3S0_001051"
     CDS             8587..9855
                     /gene="dltD"
                     /locus_tag="ACL3S0_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGR1311978.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            10010..10450
                     /gene="adcR"
                     /locus_tag="ACL3S0_001052"
     CDS             10010..10450
                     /gene="adcR"
                     /locus_tag="ACL3S0_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGR1311979.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            10450..11154
                     /locus_tag="ACL3S0_001053"
     CDS             10450..11154
                     /locus_tag="ACL3S0_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR1311980.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            11147..11953
                     /locus_tag="ACL3S0_001054"
     CDS             11147..11953
                     /locus_tag="ACL3S0_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGR1311981.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            11963..13468
                     /gene="adcA"
                     /locus_tag="ACL3S0_001055"
     CDS             11963..13468
                     /gene="adcA"
                     /locus_tag="ACL3S0_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGR1311982.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVPNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(14290..15063)
                     /locus_tag="ACL3S0_001056"
     CDS             complement(14290..15063)
                     /locus_tag="ACL3S0_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR1311983.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            15239..16642
                     /locus_tag="ACL3S0_001057"
     CDS             15239..16642
                     /locus_tag="ACL3S0_001057"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGR1311984.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            16757..17395
                     /locus_tag="ACL3S0_001058"
     CDS             16757..17395
                     /locus_tag="ACL3S0_001058"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGR1311985.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            17407..17847
                     /locus_tag="ACL3S0_001059"
     CDS             17407..17847
                     /locus_tag="ACL3S0_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGR1311986.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            17840..18271
                     /locus_tag="ACL3S0_001060"
     CDS             17840..18271
                     /locus_tag="ACL3S0_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR1311987.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            18262..18732
                     /locus_tag="ACL3S0_001061"
     CDS             18262..18732
                     /locus_tag="ACL3S0_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1311988.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            18757..19530
                     /locus_tag="ACL3S0_001062"
     CDS             18757..19530
                     /locus_tag="ACL3S0_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR1311989.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            19527..20327
                     /locus_tag="ACL3S0_001063"
     CDS             19527..20327
                     /locus_tag="ACL3S0_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR1311990.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            20386..22680
                     /locus_tag="ACL3S0_001064"
     CDS             20386..22680
                     /locus_tag="ACL3S0_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR1311991.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            22690..25806
                     /locus_tag="ACL3S0_001065"
     CDS             22690..25806
                     /locus_tag="ACL3S0_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGR1311992.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            25863..27629
                     /locus_tag="ACL3S0_001066"
     CDS             25863..27629
                     /locus_tag="ACL3S0_001066"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGR1311993.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            27775..28926
                     /locus_tag="ACL3S0_001067"
     CDS             27775..28926
                     /locus_tag="ACL3S0_001067"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGR1311994.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            29071..29955
                     /locus_tag="ACL3S0_001068"
     CDS             29071..29955
                     /locus_tag="ACL3S0_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR1311995.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            30309..30560
                     /locus_tag="ACL3S0_001069"
     CDS             30309..30560
                     /locus_tag="ACL3S0_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGR1311996.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQATE
                     TSSALISSHYLDEQDLSEKLKSELQWLELENKLLNLWEH"
     gene            30548..30835
                     /locus_tag="ACL3S0_001070"
                     /pseudo
     CDS             30548..30835
                     /locus_tag="ACL3S0_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
     gene            complement(31062..31145)
                     /locus_tag="ACL3S0_001071"
                     /pseudo
     CDS             complement(31062..31145)
                     /locus_tag="ACL3S0_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(31240..32571)
                     /locus_tag="ACL3S0_001072"
     CDS             complement(31240..32571)
                     /locus_tag="ACL3S0_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGR1311997.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQANMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKETGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(32593..34104)
                     /locus_tag="ACL3S0_001073"
     CDS             complement(32593..34104)
                     /locus_tag="ACL3S0_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGR1311998.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(34313..35260)
                     /gene="arcC"
                     /locus_tag="ACL3S0_001074"
     CDS             complement(34313..35260)
                     /gene="arcC"
                     /locus_tag="ACL3S0_001074"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGR1311999.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(35425..36441)
                     /gene="argF"
                     /locus_tag="ACL3S0_001075"
     CDS             complement(35425..36441)
                     /gene="argF"
                     /locus_tag="ACL3S0_001075"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGR1312000.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(36499..37728)
                     /gene="arcA"
                     /locus_tag="ACL3S0_001076"
     CDS             complement(36499..37728)
                     /gene="arcA"
                     /locus_tag="ACL3S0_001076"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGR1312001.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDESKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            38483..40162
                     /locus_tag="ACL3S0_001077"
     CDS             38483..40162
                     /locus_tag="ACL3S0_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGR1312002.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGSLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(40202..42286)
                     /locus_tag="ACL3S0_001078"
     CDS             complement(40202..42286)
                     /locus_tag="ACL3S0_001078"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGR1312003.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            42457..43737
                     /locus_tag="ACL3S0_001079"
     CDS             42457..43737
                     /locus_tag="ACL3S0_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGR1312004.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDSLLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            43828..46473
                     /locus_tag="ACL3S0_001080"
     CDS             43828..46473
                     /locus_tag="ACL3S0_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGR1312005.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFELFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVQLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTSFTSLQLARQEGS
                     VVAIGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            46556..47425
                     /locus_tag="ACL3S0_001081"
     CDS             46556..47425
                     /locus_tag="ACL3S0_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR1312006.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSIPTPKNLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHCFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAGKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNCNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            47419..49299
                     /locus_tag="ACL3S0_001082"
     CDS             47419..49299
                     /locus_tag="ACL3S0_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGR1312007.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            49713..50039
                     /locus_tag="ACL3S0_001083"
     CDS             49713..50039
                     /locus_tag="ACL3S0_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312008.1"
                     /translation="MILWSFDFANDHAHAFFMDNVEWSHADSYFLSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDYEEW"
BASE COUNT        15328 a         9042 c        10902 g        14819 t
ORIGIN      
        1 tagaaaacaa ttatgttgat agagcttggg caagagccca atttcagcaa aaaatgaagt
       61 aaatcttctc ataataaaac gcatcatatc aagcacgaaa attccacgag gtcaactaca
      121 gtcagaaagc tgaacaacaa gccaaaacgc ccaaaaaagg cggcaaaaag caagcacctg
      181 caagcaacgt gccgaaatgg tcaaatcctg attatgtcaa cgaattagac ccaaaaatcg
      241 ttgatatgct agtagaattt cacaagtcac aaggcacttt ggaaactccc gaggcgcaag
      301 cagaaatcgc ccaaaaacgt gaagaaatcg agcaaaggag agctgagctt gagggtaaaa
      361 aacaagagct tttgaaccgc ttgaacaaat agagtttcgc aagtattatg cttacaaatt
      421 acttgagcaa ttaactaaaa tataaaccct gcctttatat ctaggcaggg tttatatttt
      481 agaaattcac ataggttgtt acggttttta catacccagt atagtttgag tttctatagt
      541 attcagtgat aaacttccat tttctttgag caacatggat ataagtactt gttatgtagt
      601 atggatatgg gctttgtgaa tccaagtaag actgataagc ttgtatacca aaatatgctc
      661 caccaattat tgcaccccat ggccccccca ataaagcacc tatcctacca atcatataac
      721 tgattccagc accagtcatg aagttagcga atgtgttagc ttgtttattc ccatgtattg
      781 tgttgacgta attccaaaca ttaggatcgt atgatctaaa agatatattt aggtcgattt
      841 cattcttttg ataagccata taaaatgccc cattgatata gacgccgtca gcacgtcgtt
      901 caatagtgtc tacacttcca tctggattga caacctcaag aacttcatcg cttaaaatat
      961 ttacttgcgt atctccgaac cgcactgatg agccattctc aaactgagcc tcaccagata
     1021 caactttaga gtttgccgat aagctatcat cagcaaaaac aaacaagcga cggggaaatg
     1081 ctagacatac agaaaacaga cataactagc aaacacatgc atttaaacat cttagacata
     1141 acggaaactc ctttgtattt ttgatttttt tcaactttta ttatacaata aaaccaaata
     1201 aaaagaaagc ggtaacaata tgcttaatgc gaaaattttt tatatatttt tatgtttgat
     1261 cgttatcgaa actacaggct tgttgttgtt gaaaagaggt ctcgaaatgg gttatttaga
     1321 cacagaagct attatcctcg cagttttttc atttgctttt tacaacctat gttcattcgc
     1381 ttgggtctgc tctacaataa aaaacaataa aaaataaata gacgtatttt caaaaaaaaa
     1441 aaaaaatgca tatttatctt agcaaaacga cgatttaaat cgtcgttttt ttgtagtacg
     1501 acgggcatgt cgtatatctg aggtgtaagt cctcggtggg cacctgctac cggtgaaccc
     1561 aatagcgatt cccaagcctg actatcgtga ggtagcaggg agaggaaggg atagcgaaat
     1621 cgtggctcta cgaacaggaa cgtgatagta aggcgtatat agcggataag gaggcttcaa
     1681 actctaaagt ccaaaaaggt agtcgtaacc tatatgcgta aatcacgaga gtaattgaat
     1741 tcggactaag gtttgtgtga aaagataaat ctttctagag tctaaagact ctgcgtcaga
     1801 tttcctattt tcactgtaac cttttaacgt cctcatatct tgtataaacg aggaaagatg
     1861 tacgacttat cccgtgaggt ctcatgagtg ctgaaagcgt agtaacaacg aatcatgaga
     1921 agtcagccga acccatagta gtgaggaaac ttccgtaatg gaagtggagc gaaggggtga
     1981 atactcaaac agtctgggga gagactgttt gaggtctgtc gctagaaaga gaaaacgaca
     2041 gattgaagta atcctacttc acttgtgtct gtaaaacgag aggtctgata gaactggagt
     2101 ctgtcacgta ttgactagat gaaggctcac caatataaga tgtccctcag gcaccaaaac
     2161 aagaaaggaa tacgcacatg tcaaaattgc tagataagat attatcacgc gaaaatatgc
     2221 tggaagccta caatcaagta aaatccaata aaggctcagc tgggattgat ggaatgacta
     2281 tcgaagagat ggataattat ctcagacaaa actggcgctt gactaaggaa ctgataaaac
     2341 agagaaaata taagcctcaa ccagttctta gagttgagat acctaaacca gacggaggta
     2401 tccgtcaact aggaattcca acagttatgg atagaatgat tcaacaggcc attgtctaag
     2461 tcatgagccc catttgtgaa ccccatttct cagatacgag ttatggtttc agaccaaata
     2521 ggtcatgtga aaaagccatc atgaagctct tagaatactt aaatgacggc tatgagtgga
     2581 tagtggatat agacctagag aaatttttcg atacagttcc tcaagataga ttgatgtcct
     2641 tagtacataa cattatcgaa gacggagata cggaatcctt gattcgtaag tatcttcatt
     2701 caggtgttat cattaatggt caacgttata aaacactagt tggtacacca cagggaggaa
     2761 atttatctcc tctcttatcc aatatcatgc ttaatgaatt ggacaaggaa ttagaaaaga
     2821 ggggacttcg atttgtgcgc tacgcagatg attgtgtgat tacggtcgta agcgaggcag
     2881 ccgctaagcg tatgatgtat tcagtcagtc gttttattga aaaacggcta ggtttgaaag
     2941 taaacatgac caagactaag attaccagac caagagagtt gaaatatcta ggttttgggt
     3001 tctggaaatc atcagatggt tggaaaagtc gtccacatca agatagtgtt cggagattta
     3061 agcttaaatt gaagaaacta acacagagga aatggagtat agacctaaca agacgtattg
     3121 agcaactgaa tttgtctatt cgaggatgga taaactattt ctcattggga aatatgaaaa
     3181 gtatagtcgc cagcatagat gagcgcttgc gtactcgcct acgagtgatt atctggaagc
     3241 aatggaagaa gaaatcgaga cgattatggg gattgcttaa gttaggggtt cctaaatgga
     3301 tagcagataa ggtatctggc tggggcgacc attatcaatt agtagctcag aagtcggtac
     3361 ttaaacgtgc tatatcaaaa ccagtcctgg aaaaacgtgg actggtttcg tgtttggatt
     3421 attaccttga acgacatgcg ttaaaagtta gttgaaccgc tgtatgccga acggcacgta
     3481 cggtggtgtg agaggggcta gagattatcc cctactcgat taactcccct gaaatttatt
     3541 ttaattatgc aaatttcacg tatttttgat gctgagacga cgatcctggg aacttttcag
     3601 atattttttt gactatctaa atctatcatt agaaaagctt agagcgccaa aggatttgag
     3661 cgtttttctg atttttaaga ctttttccag tctctttttc gattgaagat gtaattattc
     3721 tactaactaa cttcttagta ctagccaaca acgataatca taattcctcc taaaattagg
     3781 aataataaag gcaatagttt ttgttttttc atgtaaaaaa cctcactttt gttttctgct
     3841 attttatgct aaaatattaa aaatcaaatt taattccaaa gtttgtaact aaagggggag
     3901 cgctacatgt ctaattcatt tgtcaagttg ttagtctctc aattatttgc aaatttagca
     3961 gatattttct ttagagtaac aatcattgct aacatataca ttatttcaaa atcagtaatt
     4021 gccacatcac tagttcctat cttaatagga atatcctctt ttgttgcgag tcttttagtt
     4081 ccgttggtta ctaaaaggtt agcgctaaat agggttttat ctttatctca atttggaaag
     4141 actatattat tggcgatact ggtaggaatg tttaccgtaa tgcaatccgt agcgcctttg
     4201 gtgacctatc tatttgttgt tgcaatttcc atactagatg gttttgcagc acccgtttcc
     4261 tatgctattg tgccacgcta tgcgaccgat ttgggtaagg ctaattcagc cttatcaatg
     4321 actggtgaag ctgttcaatt gataggttgg ggattaggtg gactcttgtt tgcaacaatt
     4381 ggtctgttac ctaccacgtt tatcatttta gtcttgtata tcatttctag ctttctgatg
     4441 ttatttcttc ctaacgctga agtggaggtg ttagagtcag aaactaatct tgaaattttg
     4501 ctcaaaggtt ggaagttagt tgctagaaat cctagattaa gacttttgta tcagcaaatt
     4561 tattggaaat tttttcaaat acgatttggg tttcttccat tatacttgtt tttgtaacgg
     4621 agttattaaa taaaacggaa agttactggg gatattctaa tacagcatac tctattggta
     4681 ttataattag tggcttaatt gcttttaggc tatctgaaaa gttccttgct gctaaatggg
     4741 aaagtattct ttttcctctt gtagctatgg caatagtgac actgactatt ctatattttc
     4801 caaacgcaca gatgttttta ttattttcag ctttagttgg tatgttatcg caactaaaag
     4861 aagttcctga aagtgtattt cttcaggaaa cagtagagga aaatcattta gttaatgtct
     4921 attccgttct tgaagtgatt tctacattag cattttcagt atttgttttg ctaatgagct
     4981 atattactga gagttttggt attagcatca gtttttggct atcagccatt tgtctgatga
     5041 tagaagctat tttaatttat atcagacgag attattttaa atgagagagt ggttaaaaag
     5101 tctttaaaaa tcagaaaagc gcatagtatc aggtgttgaa aaaacttgat attgtgtgtt
     5161 ttattatgag aagatttact tcattgtctc ctgaaatgga gttttgaagc aggatcactc
     5221 tatttgaaaa tatacataga aaaactgtat aatccttaaa ataagctgaa atctattgga
     5281 aacatacggt aaacaattga aaagatacta tataaagtgg tacaatggta gaaaaataag
     5341 ctagtaagaa tcactcttat tttagcgaaa aattacagaa atgaatggtt tttcttgatg
     5401 aaacagagaa aagaattgta cctctttctt ggtcggacag ccttgtattt tcttatcttt
     5461 ctagggctgc tttacttctt tagctatctt ggtcagggtc aaggaagctt tatctataat
     5521 gaattttaac ttgaaggaga atccctattg tgtcaaataa accaatagca gatatgattg
     5581 aaaccattga gcattttgct cagacacagc ctagctatcc tgtctataat gttttggggc
     5641 aggaacacac ttatggcgat ttaaaggctg attcggatag tttggctgca gtcattgccc
     5701 aactaggctt gcctgagaag tctcctgtgg ttgtttttgg tggccaagaa tatgaaatgt
     5761 tggcaacctt tgtagcgctg actaagtcag gtcatgccta cattccaatt gatagccatt
     5821 cggccttgga gcgagtttca gctattttag aagtagcaga gccaagcttg attattgcca
     5881 tttcagcctt tcccttggag caggtttcta caccaatgat aaatctagct caggttcaag
     5941 aagcctttgc ccaagggaac aactatgaaa tcacgcatcc agtcaaggga gatgataatt
     6001 actacattat ctttacttct ggtacgactg gtaagcctaa gggagtgcag atttcacatg
     6061 ataatctcct cagctttaca aactggatga ttacggataa ggaatttgcg acaccgagtc
     6121 gtccgcaaat gctggcacag ccaccttatt cttttgactt gtctgtcatg tattgggcac
     6181 cgaccttggc acttggtggt acgcttttca ctcttccttc agtcatcact caggacttta
     6241 agcaactctt tgcggctatc ttttcattgc caatcgctat ctggacatca acaccatcct
     6301 ttgcagatat ggccatgttg tctgaatact tcaacagtga gaaaatgcct ggaatcacgc
     6361 atttctactt tgatggtgaa gaattgacgg tcaaaacagc tcaaaaactg cgcgagcgtt
     6421 tcccaaatgc ccgtatcatc aatgcttacg gcccaacaga agcgacagta gctctgtcag
     6481 cagttgccgt gacagacgag atgttagcga ctctcaaacg cctaccaatc ggctatacca
     6541 aggctgattc tccaaccttt atcattgacg aggaaggaaa taaactgcca aatggtgagc
     6601 agggagaaat cattgtttct gggccagctg tttcaaaagg ttatatgaaa aatcctgaaa
     6661 aaacagcaga agccttcttt gagtttgaag gtctgccagc ctatcacaca ggcgatgtgg
     6721 gaaccatgac agatgagggc ttgcttctct acggcggacg catggacttc cagattaagt
     6781 ttaacggtta ccgcattgag ttagaagatg tctctcaaaa cctcaacaag tctcgcttta
     6841 tcgaatctgc tgtcgcagta ccgcgctata acaaggacca caaggtacaa aatctattgg
     6901 cttatgtcat cttaaaagac ggtgttcgtg agcagtttga gcgagatatc gatattacca
     6961 aggccatcaa ggaagacctg acagacatca tgatgtccta tatgatgcca tctaaattcc
     7021 tttaccgaga cagtttgcca ctaactccaa atggaaagat tgacatcaaa ggattgatta
     7081 acgaggtgaa taagagatga tggagttttt tcaacagctt cctcatttag agccatatgg
     7141 caatcctcag tattttgttt atgtgattgc tgcaaccttg cccatcttta taggtctctt
     7201 tttcaagaaa cgctttgcct ggtatgaagt gttggtaagt ctcttcttta ttgtcaccat
     7261 gttggtgggt ggaaagacca atcaactagc tgccttgggt atttaccttt gctgggaaat
     7321 attgctcctg cttttctaca agcattatcg aaaaagcaag gatggcaagt gggtcttcta
     7381 cttagttagt tttctgtccc tacttccgat tatctttgtc aaggtgcaac cagctatcaa
     7441 tggaacgcag tctttgcttg ggttcttggg aatttcttac ctgacctttc gttcggttgg
     7501 gattatcatc gagctgagag atggagtgat taaggatttt accctctggg aattcctccg
     7561 tttccttctc ttcatgccaa ctttctcgag tggtccaatc gatcgcttta agcgatttaa
     7621 tgaaaattat caggccattc ctgagcgaga tgagttgatg gatatgctgg atgaatctgt
     7681 ccgctatatc atgcggggct ttttgtataa gtttatccta gctcatgttt taggagagac
     7741 cttactacct cctctgaaga atttagcctt gcagtcaggt ggcttcttta atctctatgc
     7801 cttggcagtt atgtatactt ttggtctgga actcttcttt gactttgcag gttattctat
     7861 gtttgctttg gccatctcaa acttgatggg aatccgtagc cctatcaact ttaacaagcc
     7921 ctttttatca agggatttaa aggagttttg gaatcgctgg catatgagtc tgtccttctg
     7981 gttccgtgac tttgtcttta tgcgaatggt gatggtgtta accagaaaga aagtctttaa
     8041 aaatcgtaat gtaacctcaa gcatggccta cattgtaaat atgctgatta tgggattttg
     8101 gcatggtgtg acctggtact atatcgccta tggactcttt catggactag gcttggtcat
     8161 caatgatgcc tgggttcgca agaaaaaaac gctcaataag gaacggaaaa aagcagggaa
     8221 ggctgcccta cctgagaatc gctggattca gttgcttggc atggttgtca ctttccatgt
     8281 tgtcatgttg tcattcttaa tcttttctgg attcttgaat aatctatggt ttaaaaaata
     8341 aaaggaaata aaatatggat atcaaatcag aagttattga aattattgat gagttgttta
     8401 tggaagatgt ttctgacatg atggatgaag atctttttga tgcaggtgtc ttggatagta
     8461 tgggaacggt tgagttgatt gtggagattg agaaccgttt tgacattcgt gtccctgtaa
     8521 cagagtttgg tcgtgacgac tggaatacag ctaataaaat catagctggt attgtggagc
     8581 tacaaaatgc ttaaacgctt atggatgatc ttcggaccgg tcttgatcgc tggtttgttg
     8641 gtttttctgc tcattttctt ttatcctact gagatgcatc ataatctagg agctgaaaag
     8701 cgttcagcag tggctactac tatcgatagt tttaaggagc gaagtcaaaa agtcagagca
     8761 ctatctgatc caaatgtgcg ttttgttccc ttctttggct ctagtgaatg gcttcgtttt
     8821 gacggtgctc atcctgcggt attagctgag aaatacaatc gttcctaccg tccttatctt
     8881 ttaggacagg ggggagctgc atcgcttaac caatattttg gaatgcaaca gatgttacca
     8941 cagctggaga ataaacaagt tgtgtatgtt atctcacctc agtggttcag taaaaatggc
     9001 tatgatccag cagccttcca gcagtatttt aatggagacc agttgactag ttttctgaaa
     9061 catcaatctg gggatcaggc tagtcaatat gcagcgactc gcttactgca acagttccca
     9121 aacgtagcta tgaaggacct ggttcagaag ttggcaagta aagaagaatt gtcgacagca
     9181 gacaatgaaa tgattgaatt attggctcgt tttaatgaac gccaagcttc cttttttggt
     9241 cagttttcgg ttagaggcta tgttaactac gataagcatg tagctaagta tttaaaaatc
     9301 ttgccagacc agttttctta tcaggcaata gaagatgttg tcaaagcaga tgctgaaaaa
     9361 aatacttcca ataatgagat gggaatggaa aattatttct ataatgagca gatcaagaag
     9421 gatttgaaga aattaaagga ttctcagaaa agctttacct atctcaagtc gccagagtat
     9481 aatgacttgc agttggtttt aacacagttt tctaaatcta aggtaaaccc gatttttatc
     9541 attccacctg ttaataaaaa atggatggac tatgctggtc tacgagagga tatgtaccaa
     9601 caaacggtgc agaagattcg ctaccagtta gaaagtcaag gttttaccaa tatagcagat
     9661 ttttctaagg acggcgggga gcctttcttt atgaaggaca ccattcacct tggttggttg
     9721 ggttggttgg cttttgacaa ggcagttgat cctttcctat ccaatcccac accagctccg
     9781 acttaccatc tgaatgagcg ctttttcagc aaagattggg cgacttatga tggagatgtc
     9841 aaagaatttc aatagataat ataatataga agagttcaag aatgaaacta gttttcacgt
     9901 tttttcttga ctcttttttt gcttgtgata taattaactg gtaaacaaaa tgtcaaagaa
     9961 tagtattttt ctcttaaaaa agagaagtct aaaaggaaag gagtcagata tgagacagct
    10021 agcaaaggat atcaatgctt ttttgaatga ggtgattttg caggcggaaa atcagcatga
    10081 aatcctaata ggtcattgca ctagcgaggt ggccctgacc aatactcagg agcatatcct
    10141 tatgctcttg tcagaggaat ctttaacaaa ttcagaattg gctcgtcgtc tcaatgtcag
    10201 tcaggcggca gttaccaagg ccattaagtc tttggtcaag gaagggatgt tggaaacatc
    10261 taaagattct aaagatgcgc gtgtgatttt ttatcagttg actgacttgg ctcgtccaat
    10321 cgctgaggag caccaccatc accatgagca tacactttta acctatgaac aagtggcgac
    10381 tcagtttact ccaaatgaac aaaaagtgat tcagcggttt ttgactgctt tagtaggaga
    10441 aatcaaataa tgagatatat tacggtagag gatttgtcct tctattatga taaggagcct
    10501 gttcttgaac atatcaatta tagtgttgat agtggggaat ttgttacctt gactggggaa
    10561 aatggagcgg ctaagacgac gctcatcaag gctagtcttg gaattctgca accacgcatt
    10621 ggaaaggtgg ctatttcaaa gacaaatacg caaggtaaga aattgagaat agcctatctt
    10681 cctcaacaaa ttgccagttt taatgctggt tttccaagta cggtctatga atttgtcaag
    10741 tcgggtcgct atccgagaaa aggctggttc cgtcgtttga atgctcatga tgaggagcat
    10801 atcaaggcta gtctggactc agttggcatg tgggaacatc gagacaaacg cttggggtct
    10861 ctatctgggg gacaaaagca gcgagcggtg attgcgcgta tgtttgcttc tgaccctgat
    10921 gtgtttatcc tagacgagcc gacaacgggg atggatgcag gaagtaaaaa tgaattttac
    10981 gaactcatgc accacagcgc ccatcatcat ggcaaggctg ttttgatgat tacccatgac
    11041 cctgaagaag ttaaggatta tgcggatcgc aatattcatc tagtccgtaa ccaagactcg
    11101 ccatggcgtt gtttcaacgt tcatgagaat ggccaggagg tgggccatgc ttagtttatt
    11161 atcttatgac tttatacaac gcgccttttt ggcggttatt gctatgagtc ttttctcacc
    11221 ggtattggga accttcctca tcttgcgtcg tcagagtttg atgagtgata cccttagcca
    11281 cgtctcactt tcaggtgtag cctttggtct ggttttgggg atttctccaa ctgtttctac
    11341 tattgccatt gtcttgattg cggcggtctt tctggagtat ctccgtacgg tttacaagag
    11401 ctttatggaa atcgggacag ctatcctcat gtcaacaggt ttggctgttt ctctgattgt
    11461 catgagcaag ggtagaagct cgagttcaat gagtttggac caatatctct ttggttcgat
    11521 cgtgactatc agtgaagaac aggtcatttc cctctttgtc attgcggcgg ttgttttgat
    11581 tttgaccttt ctctttcttc gtcctatgta tatcttaact tttgatgaag atacggcctt
    11641 tgtggatggc ttgccagttc gtaccatgtc cattcttttt aacatggtga caggggtggc
    11701 tattgccctt atgattcctg cagcaggagc tcttctggta tcgaccatta tggtcttgcc
    11761 agctagtatt gccctgcgtc tggggaaaaa ctttaaatcg gttatgctgc ttgccagtgc
    11821 gattggcttt ttgggaatgg tagcaggact ttacatttcc tactatgcag aaacacctgc
    11881 aagtgcaagt attaccatta tttttgtaac tgtctttata ctaatcagtt tagtaagacg
    11941 ttttatcaaa taggagacga acgtgaaaaa aattagctta ttactagcca gtctatgtgc
    12001 cttgttttta gtggcttgtt ccaatcaaaa acaggcagat ggtaaactca atatcgtgac
    12061 aaccttttac cctgtctatg aatttaccaa gcaagtcgca ggagatacgg ctaatgtaga
    12121 actcctaatc ggtgctggga cagaacctca tgaatacgaa ccatctgcca aggcagttgc
    12181 caaaatccaa gatgcagata ccttcgttta tgaaaatgaa aacatggaaa catgggtacc
    12241 taaattgcta gataccttgg ataagaaaaa agtgaaaacc atcaaggcga caggcgatat
    12301 gttgctcttg ccaggtggcg aggaagaaga gggagaccat gaccatggag aagaaggtca
    12361 tcaccatgag tttgaccccc atgtttggtt atcaccagtt cgtgccatta aactagtaga
    12421 gcacatccgc gacagcttgt cagcagatta tcctgataaa aaagagacct ttgagaagaa
    12481 tgcagctgcc tatatcgaaa aattgcaagc cttggataag gcttacgcag aaggcttgtc
    12541 tcaagcaaaa caaaagagct ttgtgactca acacgcagcc tttaactatc ttgccttgga
    12601 ctatggactc aaacaagtcg caatctcagg actttctcca gatgcagagc catcagctgc
    12661 tcgcttggca gaattgacag agtatgtcaa gaaaaataaa atcgcctata tctattttga
    12721 agaaaatgcc tcacaagccc ttgctaacac actttcaaaa gaagcaggtg tcaaaactga
    12781 tgtcctcaat cctttagaaa gtctgacaga agaggacacc aaggctggag aaaactacat
    12841 ttccgtgatg gagaaaaacc tcaaggcttt gaaacaaaca acagaccaag aaggcccagc
    12901 aatcgaacct gaaaaggcag aggataccaa gacagtccca aatggttact tcgaggatgc
    12961 agctgtcaag gaccgcacct tgagtgacta tgcaggtaac tggcaatcag tttatccttt
    13021 ccttgaagac ggcacgtttg accaagtctt tgactacaag gctaagttga ctggtaagat
    13081 gacccaggct gagtacaagg cttactatac aaaaggctat cagacagatg tgactaagat
    13141 taacattact gataatacta tggaatttgt tcaaggtgga caaagcaaga aatacactta
    13201 caagtatgtc ggtaagaaaa ttttgactta caagaaaggc aatcgtggcg tgcgtttcct
    13261 ctttgaagcc acagatgctg acgctggaca attcaagtat gttcagttta gtgaccacaa
    13321 tgttgcccca gttaaggcag aacatttcca tatcttcttt ggaggcacaa gccaagaagc
    13381 cctctttgaa gaaatggaca actggccaac ctactaccca gataacctat ctggccaaga
    13441 aatcgcccaa gaaatgttgg cgcattgatg agaaatcgac tagttcataa gagctagtcg
    13501 gttttttgat actagatggc taacttcatt atagaccttt cagaacttta aacaataaat
    13561 aaaactcttg aaatatctgg gcttatatgc tagaatgtag ttagtgtata aggttcatta
    13621 gaacaccaaa gcccctaact agtgccatag ttaagggctt ttttgacgta tcttagcgat
    13681 ttaacgggtg tttataggct agtcagtcgg tctactcctt actatctagc catctgcaga
    13741 cgaaatacaa gataattcca gctataacat ccgctataat agtaagagcg agctctatga
    13801 taaggctcat tagtttcacc ttctctcacg aacccatagg aacgtaatcg gtaaccgatg
    13861 acaaaaatag tataccacaa taaatttaga tcatcaaggt cacttaattc ttgaaatata
    13921 gggtctaggc gacaaagtct ttaaaatcag aaaaacgcat aatatcaggt gtgcaaaaac
    13981 ttgatactat gcgttttatt gtgggaaggt ttactccatt ttctcctgaa attgagtttt
    14041 tgtccagcct ctgtttttgg ggttgctaag aaaataatgt catgtggtga atatttgtaa
    14101 atcagtcagc agacagaacg aatactcttc gaaaatctct tcacatcatg tcagcttcgt
    14161 cttgccgtgt ccatggggga cttgacttca tcagttctat ctacaacctc aaaacagtgt
    14221 ttcgagctga cttgatcaat tttcaaatct gtactttgag caagctgaga ctagcttcct
    14281 atttgatttt cattgaatat cagaaaccca ttctccatca aataattcga ctgcgtctaa
    14341 taatttttga tctggcacgg tgtctgaaat aaaggttgtg tatttggaga ggggattaat
    14401 tttaaaaaat ccagtcttgt aaaatttaga actatcaatc agtaagatgg tttcatgggc
    14461 tttgtcaata atattctttt ttgaaatagc ttggctgaga gaagcttcat aaacatattg
    14521 gtcatcaata cctcttgctg aacaaaatgc taaatcgata ttaaaatgat ctaataaaga
    14581 attttcctta tcatagttga ccacggaaca ggattgatgt ttgacctcgc cagatgtgat
    14641 aaagattttg gagctatctt taacagtttc agatagggtt tgtgcagtat gtaaaccatt
    14701 tgtaaaaata atcaaattat caagttcaga aagataggga caaagttcgt agacagtcgt
    14761 actggaatcc agatagatac acataccaga ccgaataaag tctttagcga gactagcgat
    14821 tagtcttttt tgcctagtac tttctccttc acgtatttga tgagaaagtt caattgtgtt
    14881 catagaggac agggtcacgt atccgtgctt tcttttgata agaccttgat tttctaagaa
    14941 aattaaatca cgacgtaagg tacttgtgct ggagaaagtg atttctgcca gctcttttac
    15001 ggcaattctt tttttctttt taataatttc aatcaattca agtacacgtt catcttttat
    15061 cataagctcc tcctaattta tcatttcaac tatattatag cacaaattgg aggaatttga
    15121 attattttta tgaatattgg gttaatattt gaacattatt caagtaagcg ttaatatatt
    15181 gaaaaaataa aacgtgggga ttataataaa gttaatcaag gacgaagaga gaagaaaaat
    15241 ggaagcggtt ttagcaatag atttaggtgc gacttctgga agagcaatcg ttggttacct
    15301 ttctgaaaat aaactagtaa tggaagaaat aaatcgcttt tctaatctac ctattagagt
    15361 aaaagggcat ttatcttggg atattgactt tctactagct aaaattcttg aaagtatccg
    15421 cttggctaat actagttaca agattttatc tatcggtatt gacacatggg gagttgattt
    15481 tggactgatt gataatgaag gtaagctgtt atcacaacct gttcattatc gtgatgaaag
    15541 aacaaaggga gtgttaaagg aaatatctga aatgactgaa ttagaaaaac tgtattcaga
    15601 gacaggaaat cagattatgg agataaatac cttgtttcaa ctctttaagg cacgtcaaga
    15661 atctcctgac tctttctata agaccaataa gattctttta atgccagatt tgtttaatta
    15721 tctcttgaca ggtaagtttg ctacagaaaa aagcattgct tcaacaactc aattatttga
    15781 tcctaggagt caaaattgga atcagaatat cttaaaacta tttgaattgg attcatcttt
    15841 acttcctgaa attgtttcag agggaaatgt tcttggaagg ataaaaaagg agtatggttt
    15901 aggcgatatt cctgttgtga atgtttgtag tcatgataca gcaagtgcga ttgtctcagt
    15961 acctaagaca gaaggtagtt tatttatttc atcaggtact tggtctttgg ttggagtgga
    16021 acttacttca ccgattctta ctaccgaatc cttcagttat ggatttacaa atgaagtcgg
    16081 taaagatgga gtgattacat ttctgaagaa ttgtacaggg ttgtggatca tagaggaact
    16141 aagacgttca tttgaacgaa gagggaaagc ctattctttt gatgatatta ggacaatggt
    16201 ggagaaagaa aaagaaaatc ttcctctgat tgatactgaa tcaactgaat ttgcaacaga
    16261 atctgatatg cacaagactt tgacagaata tctagcttat catcatgaaa ctagagagtg
    16321 gacagatgga caactattta agattgttta tgaaagccta gctgaaacgt ataggaaagc
    16381 gatagagtta ctagaagaac taactcataa ggtttataag aggatatatg tgattggagg
    16441 aggtgctaga gccagttact ttaaccaaat gattgctgat agaactggta aagaggttct
    16501 tacaggtttg actgaggcta cagctgtggg gaatattgtt gtgcagctca tagctatggg
    16561 acaattaaaa gggatggaag aggctcacca tgttattgag gagtttctac aattagagag
    16621 ttattactcc caaaagaatt aaaaagattg agagtttgta aatttgcctc cctccccctt
    16681 cttagctttt gtgcaggaag gggggataat tggtgaattg aaaaatattt agtgttttga
    16741 tatgaggagg acaaggatgt cagatgtaaa acaagaatta attaaatatg gtaagaagct
    16801 agtagaaaca gatttgacga aaggaacagg tgggaatctc agcgttttcg atcgtgaaaa
    16861 acaattgatg gcaattaccc cgtcgggtat tgatttcttt gaaatcaaag aatccgatat
    16921 tgtagtgatg gatattaatg gaaatgttgt agagggagaa cgcttgccat ctagcgaatg
    16981 gtatatgcat ttgattcaat atcaaactcg tgatgatatc gatgcaatta tccatgctca
    17041 tacaacttat gcaacagtat tagcttgtct cagagaacca cttccagcga gtcattatat
    17101 gattgcagtg gcagggaaag atgttcgggt agctgagtat gcaacatatg gcacgaaaga
    17161 attggctgtg aatgcagcta aagcaatgga aggtcgtaga gcagttttac tagcgaatca
    17221 tggaatttta gcaggtgcac aaaatttatt gaatgcattt aatattgttg aagaagttga
    17281 atattgtgca aaaatttatt gtttagctaa gaattttgga gagccagtag ttcttcctga
    17341 tgaggagatg gaattgatgg cagaaaaatt taaaacatac ggtcagagaa aatagggagg
    17401 atattaatgt taaaacatat accgaaaaat atttctccag atttattgaa gactttaatg
    17461 gaaatgggac atggagatga aatagtatta gctgacgcga attatccttc tgcctcatgt
    17521 gcaaataagc taattcgttg tgatggcgta aatattccag aattattaga ttccattctg
    17581 tatttaatgc cattagatag ttacgtcgat agttcaattc agtttatgaa cgttgtttcg
    17641 ggtgatgata ttcctaagat atggggtacc tatagacaga tgattgaagg tcatggtaca
    17701 gatcttaaaa cgattactta tcttagaaga gaagattttt atgaacgtag taagaaagct
    17761 tatgctattg ttgctacagg agaaacttca ctttatgcta atattatcct taagaaagga
    17821 gtagttgttg aaagagaaaa tgtttaatag aggaatttta gttgccagtc atggtgattt
    17881 tgctagcgga gctctcatga ccgcagaaat gtttgttggt gagacaacaa atgatagagt
    17941 taggacatta ggtttgatgc ctggagagaa tattgtagag tttgagcatt attttaaaaa
    18001 tcaagtggat gaactgttag actcaaatca agaggttatc gttttgactg acttgattgg
    18061 aggaagtcct aataatgtgg ctttgtcacg gtttttaaat ttggattcag ttgatattgt
    18121 aacagggttt aatattcctc tcctagtgga attaatatca aattatgatt caaaaatcaa
    18181 tttagaagaa attgttcaca atgctcaaaa tagtttgttt aatgttaaac aacaacttaa
    18241 cgtagaggag gaagaagatt tatgtctata gagtttgttc gtattgatga ccgtctggta
    18301 catggtcaag ttgtcactac gtggctaaaa aagtatgata ttgagcaagt tatcattgtt
    18361 aatgatcgca tctcagaaga taaaacacga caatctattt taaagatttc tgcaccagta
    18421 ggtttaaaaa ttgttttctt tagtgtaaaa cggtttgtgg aagttttaaa ctctgtgcca
    18481 ataaaaaaga gaacaatgct gatatataca aatccaaaag atgtgtatga ttctattgaa
    18541 ggaaatttaa aattggagta cctcaatgta ggacagatga gtaaaacgga ggaaaatgaa
    18601 aaggtaacgg gaggtgtagc tctaggtgaa gaagacaaat attattttaa gaaaatagtt
    18661 gataagggaa cgagagttga aattcaaatg gttcctaatg ataaagttac aatgttggaa
    18721 aaatttttat aaaaataatt taaggaggta cagtatatgc tattcacaca agcattactg
    18781 gtgacattag ttgggattat tgccactatt gactataatg gaccgttatt tatgattcac
    18841 cgtccgttag ttacaagtgc aatggttggc ttagtcttag gagatttcac ccaaggtgtt
    18901 cttattggtt cagctcttga attaacttgg ctcggtgtaa caggtattgg aggttacact
    18961 ccaccagata ctatttcagg tgcgattatt ggtactgcat ttggtatttt atctggtcaa
    19021 ggagaaactg ctggtatcgc tatagcagtt ccaattgcag ttgctaccca acagttggat
    19081 gttcttgcaa aaactttaga tgtttatttt gtgaaaaaag ctgataatga tgctaaaaac
    19141 ggagattatt caaagatcgg tttttatcat tattcaagtt tggttttaat cacgttattt
    19201 aaaattgtac caattttcct agctattatg cttggagggg aatatgtggc agacttgttt
    19261 gctaaggttc caccaatcgt tatgcaggga cttaactctg caggtgcttt actaccttca
    19321 attggttttg gtatgctttt aaatatgatg ctcaagaaaa atatgtgggt attcttgttg
    19381 attggattca tttgttctgt gtatggagga atgtcaacca ttgggatctc actagttggt
    19441 attgcggtag catacttcta cgatatgatt ggaagtaaac cacaagaaac aacttcaagt
    19501 agtgatgttg aggaggatct tgatctatga tgaataataa agtaactaaa gttgaactta
    19561 aaaaagtttt caaacgaagt tttatgtatg gttcttcatg gaactatgag agaatgcaga
    19621 acctaggttt tctatataca attcttccag tattgaaaaa actataccca gacaaagatt
    19681 cagcttctcc tgcaatgaaa cgtcaccttg agtttttcaa tactcatcaa acagcggcac
    19741 catttattct tggagttact tccgctatgg aagaacaaga aggaaatgaa ggtgcagctt
    19801 caattactgg tattaaagtt ggcttgatgg ggccactggc tggtctagga gatagtttgt
    19861 tctggctgac actagttcct atctgtttta gtattggtgc gtcttattct aaagacggcg
    19921 gtgctttagg tatctttatc gccttaatat tgtttaatat tattaatatt cctgttaaat
    19981 atttcggttt gaaatatggg tatactaagg gttctagtct tatccaagaa aataatacaa
    20041 aaggaacatt gaatcgcgtt acgagtatgg cgacagcatt agggctagta ctagtgggtg
    20101 gtttgattcc atcaatggtt ggtattaatt ttggattaga atttaagcag ggggaacttg
    20161 ttatttctgt tcaagaaatg attacaaaat taattccagg atttatccct atggctttga
    20221 ctttattaat gtgtaaatta attagaaaag gaaagaatcc ggttgtacta atctttagtg
    20281 ttatggctat tggagttatc ctagttgttt taggaatttt gaagtagtag aaagtgtgga
    20341 ggtggtattt gggatatcac ctccattttg gaagagaggt aaagagtgaa attatggtat
    20401 aagaaagctg cctcaaattg gaatgaagcc ttgccgattg ggaacggtca tttaggtggt
    20461 atgatttatg gttcagctac aaaagaatgt attcaactaa acgatgagac tatttggtat
    20521 agaggaaagt cagatagaaa taatccagac tcactattgc atcttaaaaa aattcgggaa
    20581 tatcttttag atggagaaat tcagaaagcc gaagaattga taaagttaac aatgtttgct
    20641 accccaagag atcaaagcca ctatgaatta cttggggaac tttacattga gcatatagat
    20701 attcagtctt gtgctctttc attgtatgaa agagagctag atttagatac agctatttct
    20761 aatgttgtgt ttgagcctaa tagttgtaat ttacaaataa aaagagaata ttttacgagt
    20821 tttaataaga atattttatg ttgccgtata gtgtcatcag ttcaaaacac attaaattta
    20881 aacattaatt tgggtagaaa taaacggttt aatgacgaag tatctaaact ggattcaagt
    20941 acaattttaa tgtcggcctc tgctggaggt agaaaaggtg ttcagtttaa agtagtatgt
    21001 cattctaagg ttacggatgg tgaagtaagt gtattgggag agacaatagt tattcggaat
    21061 gctacagagg tatttcttta tctcaaatca atgacggatt attggggaaa tatagatatt
    21121 tcttctcttc agggagaatt tagtagtatt gattacttta cagaaaaaga tgaacatgta
    21181 aaaaaatatc aggagcaatt taatagagtt gattttaaac tagactatag taaagattgt
    21241 cttagcattc caacgaatct acttcttgaa aacactaaaa agtatagtaa ctacttgact
    21301 aacttgttat ttcattatgg aagatatctg ttaatatcgt ctagtcaacc gaatggttta
    21361 cctgccaatc ttcaaggaat atggtgtgat gaattaaatc caatttgggg ttctaaatat
    21421 acgattaata ttaatactca aatgaattat tggatggtag gtccatgtga tttaccagaa
    21481 gtagaatatc cattatttga tatgctcgaa agaatgagag aaccgggaag actaaccgct
    21541 aagaaaatgt atggagctag aggttttaca gcacatcata atacggatgg ttttggcgat
    21601 acggctcccc aatctcatgc catgggggct gcaatttggg tattaactat tccatggtta
    21661 tgtactcata tttgggaaca ctatttatat ttccaagatg agcgtattct tacggaacat
    21721 tttgaaatga taaaagaagc atttcttttc tttgaagatt atttatttga ggtggatggc
    21781 tacttgatga caggtccaag tgtctcaccg gaaaataaat atcgcttaaa aaatggtatt
    21841 gaaggaaatg cttgtctatc atctacaatt gataatcaaa ttctaagata tttttgtgat
    21901 tcatgcattg gcattgcaaa acaattagga gacaattcgg attttattag tcgtgtgaag
    21961 gagttaaaaa agaaactacc taaaacaaaa ataggtagta atgggcaaat ccaagaatgg
    22021 ttagaagatt atgaagaagt agagcctggg catagacaca tttcacctct atttgggctt
    22081 tatccttata atgagattga tattcataaa actccggaat tagcagaagc agctaaaatc
    22141 actatcaata ggagattatc aaacgctaac tttttatctt cacaggagag ggagcaagcg
    22201 attaataatt ggttagtaag tggtttgcat gctagtacac aaacaggttg gagtgctgca
    22261 tggctgattc atttttttgc gagactatat caaggtgaac ctgcttataa ccagattaat
    22321 ggtttgttaa ataatgcgac tcttggcaat ttatttcttg accatccacc atttcaaatt
    22381 gatggtaatt taggtttggt gagtggaatt tgtgaattat tagtacagag ccatcataat
    22441 tggttatcac taattccagc tttaccttct gcttggtcag aaggagaagt gaaaggtttc
    22501 agagtaagag gaggatataa ggtatcgttt gcttggaaaa atggggatat aacattccta
    22561 aaattggaag gaggaaacaa agatcaaaaa gtaagagtaa gaatatatgg caaaaatact
    22621 gatgtacaaa atattgaatt ggtatttaat tcagaaaaaa ttattgagtt aaatttttag
    22681 gtataagtca tgaataaaga aaaaataaaa agaaaattaa tcacaatact gtttgtatgt
    22741 attgggatgt tatgttttgg attgttagca ggagttaagg ctgataatcg tgttcaaatg
    22801 agaacgacga ttaataatga atcgccattg ttgctttctc cgttgtatgg caatgataat
    22861 ggtaacggat tatggtgggg gaacacattg aagggagcat gggaagctat tcctgaagat
    22921 gtaaaaccat atgcagcgat tgaacttcat cctgcaaaag tctgtaaacc aacaagttgt
    22981 attccacgag atacgaaaga attgagagaa tggtatgtca agatgttgga ggaagctcaa
    23041 agtctaaaca ttccagtttt cttggttatt atgtcggctg gagagcgtaa tacagttcct
    23101 ccagagtggt tagatgaaca attccaaaag tatagtgtgt taaaaggtgt tttaaatatt
    23161 gagaattatt ggatttacaa taaccagtta gctccgcata gtgctaaata tttggaagtt
    23221 tgtgccaaat atggagcgca ttttatctgg catgatcatg aaaaatggtt ctgggaaact
    23281 attatgaatg atccgacatt ctttgaagcg agtcaaaaat atcataaaaa tttggtgttg
    23341 gcaactaaaa atacgccaat aagagatgat gcgggtacag attctatcgt tagtggattt
    23401 tggttgagtg gcttatgtga taactggggc tcatcaacag atacatggaa atggtgggaa
    23461 aaacattata caaacacatt tgaaactgga agagctaggg atatgagatc ctatgcatcg
    23521 gaaccagaat caatgattgc tatggaaatg atgaatgtat atactggggg aggcacagtt
    23581 tataatttcg aatgtgccgc gtatacattt atgacaaatg atgtaccaac tccagcattt
    23641 actaaaggta ttattccttt ctttagacat gctatacaaa atccagctcc aagtaaggaa
    23701 gaagttgtaa atagaacaaa agctgtattt tggaatggag aaggtaggat tagttcatta
    23761 aacggatttt atcaaggact ttattcgaat gatgaaacaa tgcctttata taataatggg
    23821 agatatcata ttcttcctgt aatacatgag aaaattgata aggaaaagat ttcatctata
    23881 ttccctaatg caaaaatttt gactaaaaat agtgaggaat tgtctagtaa agtcaactat
    23941 ttaaactcgc tttatccaaa actttatgaa ggagatgggt atgctcagcg tgtaggtaat
    24001 tcctggtata tttataatag taatgctaat atcaataaaa atcagcaagt aatgttgcct
    24061 atgtatacta ataatacaaa gtcgttatcg ttagatttga cgccacatac ttacgctgtt
    24121 gttaaagaaa atccaaataa tttacatatt ttattgaaca attacaggac agataagaca
    24181 gctatgtggg cattatcagg aaattttgat gcatcaaaaa gttggaagaa agaagaatta
    24241 gagttagcga actggataag caaaaattat tccatcaatc ctgtagataa tgactttagg
    24301 acaacaacac ttacattaaa agggcatact ggtcataaac ctcagataaa tataagtggc
    24361 gataaaaatc attatactta tacagaaaat tgggatgaga atacccatgt ttataccatt
    24421 acggttaatc ataatggaat ggtagagatg tctataaata ctgaagggac aggcccagtc
    24481 cctttcccaa caccagataa atttaatgat ggtaatttga atatagcata tgcaaaacca
    24541 acaacacaaa gttctgtaga ttacaatgga gaccctaata gagctgtgga tggtaacaga
    24601 aatggtaatt ttaactctgg ttcggtaaca cacactaggg cagataatcc ttcttggtgg
    24661 gaagtcgatt tgaaaaaaat ggataaagtt gggcttgtta aaatttataa tcgcacagat
    24721 gctgagactc aacgtctatc taattttgat gtgattctat atgacaataa tagaaacgaa
    24781 gttgctaaga aacatgttaa taatttgtcg ggtgaatctg ttagtctaga tttcaaagaa
    24841 aaaggagcaa ggtatattaa agttaaatta ctaacgagtg gagtgccttt gagtttagca
    24901 gaagtagagg tttttagaga atcagatggt aagcaatctg aagaggatat agataaaata
    24961 acagaagata aagtagtctc tacaaataag gtagctactc aaagttcaac caattatgag
    25021 ggtgtagctg ctttagcagt tgatggtaat aaagatggag attacggaca tcattcggtg
    25081 actcatacta aggcagattc taacgcttgg tggcaggtcg atctgggaga agagtttacg
    25141 gtttctaaag ttgatattta taatagaaca gatgccgaac ctcagcgttt atctaatttt
    25201 gatgttattt ttctatcttc atcaggagaa gaagttttta gaagacattt tgataaagta
    25261 gttgatggtt tgttatcttt aaaagtacct tctgtagggg ctaagctagt caaaatagaa
    25321 ttaaaatcag cagctattcc gttaagttta gcggaagttg aagtctatgg ttcaaagaga
    25381 actccgaaga aactttctaa tattgcatta accaaagaaa ctcgacagag ttcaacggat
    25441 tacaatggtt tttctcgtct agcagttgat ggaaataaaa acggagatta tggtcatcat
    25501 tcagtgactc ataccaaagg agattctcct tcatggtggg agatagattt agcacaaacc
    25561 gaagaattag aaaagttaat tatttataat agaacagatg ctgaaattca gagattatca
    25621 aattttgata ttattatata tgattcaaat aatcatgaag tttttaaaca acatattgac
    25681 agtttagaaa gcaataatct atccatagac ttaaaagggc tgaagggaaa aaaggttaga
    25741 atttctttga gaaacgcagg aattccttta agtttggcag aggtagaggt ttatacttat
    25801 aagtaatttt aaaaattatc atcggtagta tgaaagaaac agaaaaataa gaggaaaata
    25861 gtatgattca acatccacgt attgggattc gtccgactat tgatggtcgt cgtcaaggtg
    25921 tacgcgaatc acttgaagta caaacaatga acatggctaa aagtgtggca gatttgattt
    25981 caagcacatt gaaatatcca gatggggaac ctgtggaatg tgtgatttct ccatctacca
    26041 ttggtcgtgt tccagaggct gcagcttccc atgagttgtt caaaaaatca aatgtttgcg
    26101 caacaattac agttacacca tgctggtgtt atggtagtga aactatggat atgtctccag
    26161 atattcctca tgctatttgg ggatttaatg ggacagaacg cccaggagct gtctatcttg
    26221 cagctgtact agcttcacat gctcaaaaag ggattccagc ctttgggatt tatggtagag
    26281 atgttcagga agctaatgat acagatattc cagaagatgt caaagaaaaa cttttacgtt
    26341 atgcgcgtgc agctcttgca actggcttga tgagagacac tgcttaccta tcaatgggta
    26401 gtgtttcgat ggggattggc ggttctattg taaatccaga tttcttccaa gaatacttag
    26461 gaatgcgaaa tgaatcggta gatatgacgg agttcacgcg ccgtatggac cgtggtattt
    26521 atgacccaga agagtttgaa cgtgcgctca aatgggtgaa agaaaacgta aaagaaggat
    26581 tcgaccataa ccgtgaagac cttgttttaa gccgtgaaga aaaagataga caatgggaat
    26641 ttgttattaa gatgttcatg attggacgtg acttaatggt tggtaaccca agacttgctg
    26701 aacttggttt tgaggaagaa gcagttggtc accatgcttt agtagctggt ttccaaggtc
    26761 aacgtcagtg gacagaccat tttccaaatg gagattttat ggaaactttc ctcaatactc
    26821 agtttgactg gaatggtatt cgaaaaccat ttgtatttgc gacagagaat gattcactaa
    26881 atggtgtgtc tatgctcttt aattatctat taacaaatac tccacaaata tttgctgatg
    26941 tgcgtactta ttggagtcca gaggctgtta aacgtgtaac gggacatact ttagagggtc
    27001 gtgctgcagc tggcttctta catctaatca actctggttc ttgtacattg gatggtacag
    27061 gtcaagctac tcgagatggc aaacctgtta tgaaaccatt ctgggagttg gaagaaagtg
    27121 aagtgcaggc tatgcttgaa aatacagact tcccaccagc aaaccgcgaa tacttccgtg
    27181 gaggaggatt ctcaactcgt ttcttgacga agggggatat gccagtaaca atggtacgtc
    27241 tcaatcttct aaaaggggtt ggtccagtgc tacaaattgc agaaggttat acacttgaac
    27301 ttcctgaaga tgttcaccat actttagata atcgtacaga tccaggatgg ccaactactt
    27361 ggtttgctcc acgtttgaca ggaaaaggtg ctttcaagtc tgtctatgac gtcatgaata
    27421 attggggagc taatcacgga gccataacat atggacacat tggagcagac ttgattacct
    27481 tggcttctat gttgagaatt cctgtcaata tgcataatgt acccgaggaa gatatcttta
    27541 gacctaaaaa ttggtcctta tttggaacag aagatctaga atcagcagac tatcgtgcat
    27601 gtcagttgtt gggaccgcta cataaataaa aattgtgtat ataggaggtg aacttatgtc
    27661 cctcctatcc ttttaaaaag atttgttaaa caattcacaa ataattgaaa acgaatacaa
    27721 aaactaatat aatgatgtta aatagatagc gcggaggcgc aggaggaaaa ttatatggct
    27781 acattttatg ttccggcagt caaccttatt ggtaaaggtg ttgtaaatga agtgggtcct
    27841 tatatcaagg aacttggcta taaaaaggca cttttggtga cagataagta catcgaaggc
    27901 agtgacattt tacctaaggt tttaaaacca ctggatacag aaggaatcga atatgtcatc
    27961 tttagcgatg tagagccaaa ccctacttgt aaaaatgtca cagatggggt agctgctttg
    28021 caagaacatg gctgtgactt tatcatcagt cttggcgggg gttctccaca ggatgcagct
    28081 agttgtattt ctatcatggc tacaaatggt ggaaaaccac aggattatga agggcttcat
    28141 aagtctgcta aaaaaggctt gccagttgtg gctatcaata caacggcagg aacttctgca
    28201 gaaatcacta ttaactatgt gattactgat gaagaacgca aggttaagat ggtaatggtt
    28261 gacaagaata gccttgctct tatctctgtt aatgacccgg aactcatgct ttccaaacct
    28321 aaaggcctga ctgctgctac tggtatggat gctctgactc acgctgttga agctttggta
    28381 acacctggtg cttatgatgt aaccaagaaa ctgtctattg gtgctattga gcttatcaag
    28441 gaatatcttc ctcgtgctgt agaaaatgga catgatattg aagcgcgtga aggtatggtc
    28501 aatgccatct tccttggtgg tatgagcttt aataatgctg gtcttggtta tgttcactca
    28561 atggctcacc aactcggtgc agtatataat ttgccacatg gtgtttgctg tgccatgttg
    28621 ctaccagtta tagaacgtga aaatgctaaa cgtgtaccag aagctttccg caatgttgcc
    28681 aaagccttgg gacttcatgt agaaggtaaa tcagatcaag aatgtgccga ttatgcgatt
    28741 gttgagattg agaagctttc tgagacagta ggtattccta agaaactgac tgaacttggt
    28801 attgaagaaa aagatttcga ctttgaatac ctttctaaga atgccttgat tgatgcctgc
    28861 gcaccaggaa atccatttat gccaacctta gaagaaacga ttgcctttta taaagagtta
    28921 ttttagcaag agattggacg acaataggac aattcacctc taattattga catttcagga
    28981 aaaatcgcag taaaaacggc acagccttct ttaaatgtgc tataatacta gaaaaatact
    29041 tgtggaggtt ccattatggc aatatttttc atgatttttc tgattgtttg tgtgctccta
    29101 ttggtgatag tcacactgag tacagtttat gtggttcgtc agcagtcggt ggcgattatt
    29161 gaacgctttg ggaaatacca aaaggttgct aatagcggta ttcatattcg cttgcctttt
    29221 gggattgact cgattgcagc acggattcag ttgcgcttgt tgcaaagtga tattgtggtt
    29281 gagactaaga ccaaggacaa tgtgttcgtt atgatgaatg tagcgactca gtaccgtgtc
    29341 aacgagcaga gcgtgacaga tgcttactat aaactcatac gtccagaatc tcagattaaa
    29401 tcttatatcg aagatgctct tcgctcttct gttccaaaat taaccttgga tgaattgttt
    29461 gagaaaaaag atgagattgc ccttgaagtt caacaccaag tagcagaaga aatgaccact
    29521 tacggctaca ttatcgtgaa aaccttgatt accaaagtcg aaccggatgc agaagttaag
    29581 caatccatga atgaaatcaa tgcggcgcaa cgtaagcggg tcgcagcaca agaattggcg
    29641 gaagctgaca agattaaaat tgtcactgca gctgaagcag aagcagaaaa agaccgcctt
    29701 catggtgtgg ggattgccca acaacgtaag gcgattgtgg atggattggc agagtctatc
    29761 accgaactca aggaagccaa tgttggcatg acagaagaac aaatcatgtc tatcctcttg
    29821 accaaccagt atttggatac cttgaatacc tttgcctcta aaggaaatca aaccatcttt
    29881 ttaccaaata ctccaaatgg tgtggatgat atccgaacac aaatcttgtc agcccttcgc
    29941 gctgagaaga aataatagac taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg
    30001 ccttgccgta tagatgttac tgacgaagtc agttctatct gcaacctcaa aacagtgttt
    30061 tgagcaacct gtggctagtt tcctagtttg ctatttgatt ttcattgagt acaaagagct
    30121 tggcaacagg ctctttttgt attgcgttta ttaagaaaaa caaaaaacat cgatatacat
    30181 ttaactaaaa attattgtat gttatctccc ttaattagga atgataaggg aataactaga
    30241 aagatttgtg aatacaaact atttctgata tacaaaatat acagtaataa tgaatgatgg
    30301 gagatgggat gaaagaattt caatttgaga gaaagcagcg tttttctttg aggaaatatg
    30361 caataggagc ttgttcggtc ttgctaggaa cgagtttatt ttttgctggt atgggtgctc
    30421 agcctgtaca ggctacagaa acgagttcag cactaatttc aagtcattat ttggatgagc
    30481 aggatttatc tgaaaagctg aaatctgagt tgcaatggct tgaattagaa aacaagcttt
    30541 tgaacttatg ggagcattag gttactatga aggatttgtt ccttacgttt caaattaata
    30601 caaaaaccaa gctgaagaag acaaaccgct atctgataaa tatattttcg aaaaaatctt
    30661 aggaaaaaca tatgcagcct tcaaaaaaga tcaaattaat gagcgtgtcg agaaattagg
    30721 taagttaaaa cctattacaa taaattacaa cggaaaatca gaagtaattg atagtaaaga
    30781 aaaattacaa gagcttatga ataaagccgt taaagacgaa gtggctcaaa tatagtaaaa
    30841 tgaaataaga acaggacaaa tcgttcagga cagtcaaatc gatttctaaa aatgttttag
    30901 aagtagaggt gtactattct agtttcaata tactataaaa tcaggcaata ccacggctaa
    30961 aaagtttgag tttatcgaaa caccagtgca aaaactgaaa aaagcgattt ataaagctca
    31021 tctcaaagat tcagatgact ttagaccaga aacatccaca caaatctttt tgaaagctgt
    31081 ttgaagcttt gtccttgctt tcttagttca tagatctgaa ctttatcttc ataactcaat
    31141 ttcataataa aacaccccaa aagttagatt tattctgtct aacttttggg gtgcagttca
    31201 ttaatcggtc gatttttttt ggtagaaaca gttgcctgat taagttgcaa gtcgatagac
    31261 ggcttcggca taaatatcca tagcacggta caaatcttct agaacggcac attcatttgc
    31321 ctgatgttct gtctgcttcg ctcctgggaa taaggcgccg aaggctacac aatttggcat
    31381 ggtgcgagca aaagtggcac caccggatga aatagcagga ctgttatcgc cagtcttttc
    31441 ttggtagatt tgcatcagtg tgctaacgag tttactgtct tttgcgacgt atagaggcgc
    31501 tagatagtca aactcttcgt agcggagttg gtagttttgt gcacatcttg taagcaactc
    31561 tactagttct tccttgtcag ctaagacagg agtccgaatg tcaatacgga tttcagaacg
    31621 ttcatgattg atcatgagac ctgcgacatt aaaggatagg tgaccagaag gttcatctgc
    31681 tatatcacca aagatttgtc ttcctgtgcc gtcttgacct gcttgtgttg caagaaaact
    31741 gagagcaggg tgttcttgga gaggagcaag aatggtagct agtcggatga cagcattgat
    31801 accttgacta gcatccttag catgctttgg cactccgaga accgttacgg tttgttcagt
    31861 ggattggtaa tcataaccag tttctttgag accgttacaa acctgttcat agaggggacc
    31921 ttggtagttg gccttgtctg gtacaacgtt aaaggcgcct cctacttcaa gctctagttg
    31981 atccgatcca gggccatgaa gtttgacctg tagaagccct ttttcagcat aggtcagagg
    32041 aaaagatgag tcaggtgcaa agcccatgtt ggcctgttct tcgatggtat tgtagcgtgc
    32101 catgcagcgc cagagggttt cctcatcggt accaaagata aagcgtacgc gctttttgaa
    32161 ctgaatacct tggtccagca agctttttac tgcatagaga gctgcgagcg aagggccttt
    32221 atcatcttgg acaccacgtc cgaataccca gccgtctttg atagttgctt caaatggcgg
    32281 tgtctgccaa tctgcttcat cacctgatgg aacaacatcc aaatgacaga gaatggccag
    32341 aagctctgct ccctgaccga tttctgcata tccgtaataa cctttagggt caagataggt
    32401 agtgaaacct atgtctcgac aaatctctaa agttttttct aggacatctt ggattgcttg
    32461 tccaaaaggt gttccatttt ctccttcatt gagtactgaa ggataggaaa tcaaggtttt
    32521 taatgatata agaaattcat ctttaacttg atttgttata tctattttca tggaatcacc
    32581 tcactcacta ttttatagga atggaaggaa ggttccaagg agaagaaggg cgatggtcac
    32641 tacaataata gcgactacga gtttgcccat gaatttccac caagtaccaa tgttgatacg
    32701 tccaagtgca agagctccca tcacaatacc agatgttggt gcaatcaagt tcaagacacc
    32761 tgaagcagat tggtaagcag tgataatcaa gctaggacgg acatttacaa attctccaag
    32821 tggagccatg atacccatag ttgcgctggc aagaccagat gaagatggga tcaagaatga
    32881 cataggtaga tagaagatat aagttacaac gataaagact tgtgaagata gaccgctcaa
    32941 gccttcttta ccccagttga ggattgtatc ggtaatcata ccgtcgttca tgataacttg
    33001 aataccacga gcaatcgcta cgatcaaggc aacactgagc aagtcagcag caccattcat
    33061 gaaggaagag ataatcttat cttctttaag accataaata acaccaatca ggatacccat
    33121 aaaggcaaag agcattgcgc cttctgggaa gtaccaagta cctagtgcag aagtagatga
    33181 accgacaata ttaccaataa ctggaagacc agtcaaccaa gcattaaagt catcaaaaat
    33241 ggtaacgcca aggtctgtcc atggaatgaa gctcaatacc atcaagatga atgtcaacac
    33301 aaataaaaag agaactgatt tttgtttgct gctaagtgta gattctacag atgaagattc
    33361 ttctacgtta aagtgtttca aatcttcttt gcgagtacta taaaccagtg acttagtcgg
    33421 atctttttga atcttatccg cataacggta aacaaaccaa gtactaagag cagtcaaggt
    33481 aacccagaag atcagacgaa gtacgatacc gtcccctgta ccaactcccg cagtcgctga
    33541 agcaatacct gtcgcaaatg gattcagagt agatgccaaa cagccgattt gagaaccgag
    33601 caaaataatt gcaacaccag tcaggctatc aaaaccaacg gccatcataa ctggcacaag
    33661 gagtggatag aaggccattg tttcttcacc cataccataa gttgtaccac cgagggcaaa
    33721 caaaggcatc agtaccaaaa ttaacatttt ttcgcggccc ttatacttct tcacgataga
    33781 ggcaatccct acgtcaagag caccagtttt gttgacaatg ccaaggaaac caccaaccat
    33841 aaggatgaag aaggctacat caatcgctgc gctcgtttct ttaatgagcg aaccttcctc
    33901 tggatgagta cctagcatag cccgaatcgg tgccatgagg acatcccaaa tcccttgtgg
    33961 attttgaggc tgagtctcgt aaataccttc tataaaggcc cccgcaggga taaaccaagt
    34021 tagcactgcc ataatagcaa tgattatcaa taatacggtg taagatgaag gcatcttaaa
    34081 ccctttttta gctttttcac tcatttgttt ttcctcctga tgtctaacaa agtgtaaaaa
    34141 accaactact ttcttaaata aacattcaag aaaacgcttt ctatttatat ttgttttacc
    34201 atattaaagt ctaaaactag tatcttttga aatattgtac atgttttcaa gaataatttc
    34261 taatttgata taaagatact agaaatagaa tacatcttat tagtaaaaca acttatcctt
    34321 tttcaataat tgttccgctt tcagattcaa tcaaggcgcc tagattttca agggaagtaa
    34381 taactgcttt tccttctgga cgaccattga caaaagcgat agctgcttct acttttggaa
    34441 gcatgctacc tggtgcaaac tgatcttgtt tgatatattc ttccagctgg gcaacattca
    34501 catgttccaa tttttcctgg tttggcttgt tgtagttaac aaatacataa tctacacctg
    34561 tcaaaacgat gaagaggtct gcatcaacca attctgccaa acgttgggaa gcgaagtctt
    34621 tatcaataac cgcttcgaca ccagtcaaat gtccattgtt ttctttgacg acgggaatac
    34681 cgccaccacc tgcagctacg acgacttgac cattatttaa aagagtacgg atggtttcaa
    34741 tttctttgat gtcaacaggt tttggtgagg caacgacctt acgccagcca cggccagcat
    34801 cttccttgaa agtcgctccg ctcttttcgg cttctgcttt tgcttcttct tctgaataga
    34861 aaggaccgat tggtttactc aagttaacaa aagctggatc atttttatct acgacaactt
    34921 gcgttacaac agaggcaaca tttttttcga tgccttcatc caagagagca ttttgcaaag
    34981 catttttcaa ccagaaaccg atgctacctt ctgtcatagc gacaagtgag tcgagtggga
    35041 aggcagggtt cttttcagag tctgatgcca aatgttggag caagagattc ccaacttgag
    35101 gtccattacc gtgagtgata atcaaatcat ctccattttt aatcaatttt acaagatgct
    35161 tagctgtttc aactaaagct tcttgttgag cctttgctga tgggtcagaa gaaagaatcg
    35221 catttcctcc caaagctact acaattttac gatttgccat aaattctcct ttatcacact
    35281 caatagaatg cgtttagatt tcaatttaat gatttttcac atattttata agaaataata
    35341 gattaccatt atataaaaga ggaccggact aaagctatta gtcgcagccc tcatagctgt
    35401 tggtagacgg tttattatct aaaattatac tttaggaata taaaggttac caagtgtagc
    35461 agccataaca gctttgatag tgtgcatacg gttttctgct tgatcgaagt ggcgagcgta
    35521 cttgctgcgg aagacttcgt ctgttacttc catttcttct acaccaaatt tttcagcaac
    35581 gtctttacca taaacagtgt gagtatcgtg gaatgctggc aagcagtgta ggaagatcaa
    35641 gttttcattg cctgcttttt taactaagtc catattgact tggtaaggtt taagaagagc
    35701 tacacgttct gcgaatttgt cttcttcacc cattgatacc caaacgtctg tgtaaagaac
    35761 gtctgcatct ttaactgctt catcagcatc ttcagtgatg agaacatgtg cgccactttc
    35821 tttagcaaat ccttctgcca attcaacgat ttctttttct gggaagagtt cttttggtga
    35881 gaagatgtga acattgacac caaggatagc acctgttacg agcaagctgt tggcaacgtt
    35941 gttacgtcca tcaccacagt ataccaatgt caagccttcc aagcgaccga agttttcttg
    36001 aacagtcaag tagtcagcga gcatttgagt tgggtgccat tcgtcagtta gaccgttcca
    36061 tactggaacg cctgagaatt ctgccaattc ttcaaccata cgttggctga atccgcggaa
    36121 ttcaatcccg tcaaacatac gtcccaatac tttagcagta tcttcagtag attctttttt
    36181 acccaactga atatcatttg ctccgaggta ttctgggtga gcaccaaggt cgatagccgc
    36241 agttgtaaag gctgcacgag tacgagtaga tgttttttca aataggagag cgatattctt
    36301 gccagcaagg tagtggtgtt gaatattgcg ttttttcaaa tctttcaagt gagctgaaag
    36361 accaataagg tattctaact ctgcacgggt aaagtctttt tctgctaaga agctgcgtcc
    36421 ttggaatact gaatttgtca ttttattatt tcctctttct attttttaca ttttctattg
    36481 acgaataccg aacagcgatt acacttcttc acgttcaaat ggcatagaca tacaacgagg
    36541 tccaccacgg ccccgaacca attcacttcc gcgaatctta atcaagcgaa gcccgtattc
    36601 ttccaaaatc ttattggtca cggtattgcg gtcataaaca actaccacac caggtgcgat
    36661 ggtcaaagtg ttagaaccgt cgttccattg ttcacgcgca gctgctacga tattgccacc
    36721 accgcaacga atcaaatgaa ctttttctac accaaggttt tgagcaagaa gttcagctaa
    36781 gtcacctttc tcttcaacga ttttaagttt ttcgttttcg taagtaactg agtaaacgtg
    36841 aaggtcgcct tcgatttctg ggtgaatagt gaacttgtca tagtctacca tagtgaagac
    36901 agtatccaag tgcatgaatt tacggttgtt agcaaattca aaggccaaaa ctttcttgaa
    36961 gccaacattt ttcttgaaga tgttgaccaa aagtttttcg atagaagctg cgtctgtacg
    37021 ttgagagata cctactgcaa ggacgtcttt agaaagaact agctcgtctc caccttcgat
    37081 acgcgtatct tcttcacggt tgtagaccaa atccactttt ccgccataga ttgggtggta
    37141 tttgaagata tacttaccgt agagtgtttc acggttacga gtgtctgcaa acatgtggtt
    37201 aagcgatacg gcgtttccaa ttgttgcaaa tgggtcgcga gtgaaataga ggtttggcat
    37261 cgggtcaatt gcaaatggat aatctgattc aactaagtca gttagatctt tagattcgtc
    37321 aggaatttct ggcaattcaa ctttttgaat cccagccatt gttttttcaa ccaattcttg
    37381 gttgtccttg atgccgtgaa gcaattcacg aatagcaacc ttggtttgac gatcacggat
    37441 gttggcttcg tctaagtatt cctcgataaa ttgatcgcgg atttctggag aggtcaatga
    37501 ttcagcagcg agttgttcta ggtagagaac ctcaattcct tcatcgcgaa gagcttgggc
    37561 aaatgcatca tgttcttttt gagcatcttc caagaaagga atatcatcaa aaagaagcct
    37621 ttcaagatag tccggcaaca agttttctaa ctccttgcct ggacggtgca acataacttt
    37681 tttcagtttc ccaatttctg agaagacctg aattggatgt gaagacatgt attttcctcc
    37741 ttaaaaattt tgacttggca ccattttggg taccgcttac atgtatgtta taacgcaatt
    37801 cctaggtaat gtcaatggct ataatttctc ggaaaataat ataaattatg atgtttagca
    37861 caattttatg ttattataca taacatagga tagaatacat agatacaaat gcataaactt
    37921 ctataaaaag gatataaaat ttttttaaaa aatttttcaa aaaatataca aatgaccaaa
    37981 aagtgtccaa ttatcatctg gttatcactt ggatctgtat aaagagaaat gtttgtgtga
    38041 aaggataaaa agatgcaaca ttcttttgaa gatagatttt ggagaagcat ttcttgttca
    38101 attgtacaaa ttatagaatc ttttctgagt atttaggaag agataattat cttattgacc
    38161 ctctttttat tttttgttat agtcgacgag gtgatagttt agaataatca cttattcaca
    38221 atctgtggaa aagtctggag agtgaatggt cttcacacaa tgacctgaaa gaagcctgag
    38281 aataattatg gagagtagca ttctgagagg tgttagcaga accatatgac agagctgttt
    38341 gaagagggaa tattgaggag caaaatcctg agcctaccag ttggagttgg aaagagctgg
    38401 ctgttagatc atggtttatt atccacaacc tgtggataac cttgtgaaca agagaagttg
    38461 ctaaagaagg agatatataa cgatgaagaa aatcaaaccg catggaccgt taccaagtca
    38521 gactcagcta gcttatctgg gagatgaact agcagctttt atccacttcg gtcctaatac
    38581 tttttatgac caagaatggg ggactggaca ggaggatcct gagcgcttta acccgagtca
    38641 gttggatgcg cgtgagtggg ttcgtgtgct caaggaaacg ggcttcaaaa agttgatttt
    38701 ggtggtcaag caccacgatg gctttgtcct ttatccgaca gctcacacag attattcggt
    38761 taaggtcagt ccttggagga gaggaaaggg cgacttgctc cttgaagtat cccaagctgc
    38821 cacagagttt gatatggata tgggggtcta cctgtcaccg tgggatgccc atagtcccct
    38881 ctatcatgtg gaccgagaag cggactacaa tgcctattat ctggctcagt tgaaggaaat
    38941 cttatcaaat cctaactatg ggaatgctgg taagttcgct gaggtttgga tggatggtgc
    39001 cagaggagag ggcgcgcaaa aggttaatta tgaatttgaa aaatggtttg aaaccattcg
    39061 tgacctgcag ggcgattgct tgattttttc aacagaaggc accagtatcc gctggattgg
    39121 caatgaacga gggtatgcag gtgatccact gtggcaaaag gtgaatcctg ataaactagg
    39181 aacagaagca gagctgaact atcttcagca cggggatccc tcgggcacga ttttttcaat
    39241 cggagaggca gatgtttcca tccgtccagg ctggttctac catgaggatc aggatcctaa
    39301 gtctctcgag gagttggtcg aaatctactt tcactcagta gggcgaggaa ctccactctt
    39361 gcttaatatt ccgccgaatc aagctgggct ctttgatgca aaggatattg aacgacttta
    39421 tgaatttgcg acctatcgca atgagctcta taaagaagat ttggctctgg gagctgaggt
    39481 atctggtcca gctctttccg cagactttgc ttgtcgccat ttgacagacg gccttgagac
    39541 cagctcttgg gcaaacgatg cagacttgcc catccagtta gaactcgact taggttctcc
    39601 taaaactttt gatgtaattg agttgagaga agatttgaag ttaggccaac gtatttctgc
    39661 tttccatgtg caagtagagg tggatggtgt ctggcaggaa tttggcaggg gcttcacagt
    39721 tggtcataag cgcctcttgc gaggttcgct agtagaggca caaaaggtgc gcgtgatgat
    39781 taccgaggca caatctattc ctgtattgac caagatttcc ctttataaaa ctcctggatt
    39841 atcaaaaaaa gaagttgttc aggaactagc atttgcagaa aaaagcctag ctgtggcaaa
    39901 gggagaaaat gcctatttta cagttaagcg cagagaatgt agtggtcctt tagaagctaa
    39961 gatttcgatt caaccgggga caggtgtcca tggtgtcgcc tatcaggacg agatttatgt
    40021 ccttcaattc caagcagggg aaagcaaaaa agatttgcat ctaccaaccc tgtatttcgc
    40081 aggagataaa accttggatt tctatctgaa cctaacggtg gatggtcagc ttgtggatca
    40141 acttcaagtc caagtttcat aaaagaagaa cctttgcgcg atgcaaaggt tcttttggtt
    40201 attagtgact tggtagccag ctgagggtga aagttagttg ttcagctttt aagaggtctt
    40261 ggtgttgaat agttgatacg agtgttttgt tcagtcggca ttctttgaca aagttaaaat
    40321 ggttgtggtt ttgtttagta tggatatcca gccatttatc ttctttagct aggtagactc
    40381 gtagatggtc aaagagaggg attccgaggt catagcttgg ttttcctgga caggttggat
    40441 aaaatccgag agctgaccag atgtaccaag cagagagact accattgtct tcatctccag
    40501 gataggcttc ccaacttggg tgaaaagctt tctgacggag cgtcttgata agaagggcag
    40561 tgtagtcagg gtaatcgctg tagcggaaga gataagggat gtggaaacta ggctggttgg
    40621 aaatggctat ttgtccaaaa ggagcagtag ccatctcgct catttcgtga atttcataac
    40681 catagcctgt tgtttcaaag aggggagcat cttgacaggc tttcaaaaga tagttgctaa
    40741 aggtttcttt tccacccatc agttggatta agccagggat gtcgtggaga acgcctaaag
    40801 tagcttgaat ggcagagcat tcagcgtagt ctcgccccca actataagga gagaagtcag
    40861 ggtgaaagtt tccttgattg tctcgtgctc gcatgtaacc tgtctcagcg tcaaatagct
    40921 ggcggtaatt ttgtgaagca gccttgtagg tttcagcgat ttctatgttc tctagttttt
    40981 tggcacagct ggcgatacaa aagtcactat aggcatagtc tagagtatgg ctaacacttt
    41041 catggtggtc ggtagagagg taacctagtt cttggtattg ggctagtccg tggcggccat
    41101 tgatgccgag agggtcggct ttgctggctg tttcgagcat ggcttggaag agttctcctt
    41161 ctaggtcggg ggccatgtcc ttacaggcgc tatctgcgat aatgccatct agcagtgtac
    41221 ctggcatcat accccgttca tctggagcca gccattttgg aaggaaacca gtatcgcggt
    41281 agctattgag gaaaccttct aaaaagcgtt gatagtgctc cggtatgata agggcaaaga
    41341 gggggaaggt ggtgcggaag gtatcccaga aaccattgtt gctaaagagg acaccaggct
    41401 tgacagtacc agtagccaga tccatgtgga tggctttccc tgactcatca acctcataaa
    41461 aagtctgtgg gaagaggaag agtctgtaga gacagtggtc aaagaaggtt cggtcagcct
    41521 ctcctgtctc tataatgtca aaacgatgga ggagattttc ccaatccgct tgggcacttg
    41581 ttttacagct atcaaaatct tcttgaggta gattgattag agcttgagaa ggagagatga
    41641 aagaagtggc tagttgcatc tcggtttgac tacttgctaa gtcaattcgc cagtctccag
    41701 cttcttggct gatagcaaga atatccgtgt tcatttgcag ggcagtgaac atcgttagcg
    41761 aatttttgtt agtttcagtt ttaccttctt gtcgcagggc aagagtccgc ttatctactt
    41821 gctctactgt cagttcatct gctgcgtgaa gatagaggga gagggctttg ccttgctttt
    41881 gattcaaacg aatagaagca ccatagcaag tcggtgtgag ctgggtttca atctgataac
    41941 gcagagaaaa gagcttcaaa tagtgaggct ggaagcaagc tttatctata tcataagaag
    42001 actggcggtg aaagaggctg tctcccccca gttgactggt gacaggtgtc agaaggagcc
    42061 aagagtagtc cccaatccaa ggactgggct ggtgagttaa tcgaatcccc tgaaagatag
    42121 gcagatgcgg atcaaaaaac caagatccat cctggtcact ggtctggggc acaaagtaat
    42181 tcataccaaa aggcacgcct gtgtatggca gggtatttcc ccgagagaag gcatgcttgc
    42241 tagcagtacc aaagcgggta tcgatggttt caagtagtgg tttcatagtc tttcctttag
    42301 ctgtttttct acattatatc agaaaaagag ggcctttaga aaaggagttt caaaaataac
    42361 tattttgtag aaaaatgact atcatttgtg tatgtatttt ctgtctcaaa agctatatac
    42421 tgaacatgaa acttgtttga aagagggaat tgcacgatga tttattcgaa agaaattgtt
    42481 agagaatggc tagatgaagt agcagagcgg gccaaggacc atccagagtg ggtggatgtt
    42541 ttcgagcgtt gctacaccga taccttggac aatacggttg aaatcttaga agatggttca
    42601 acttttgtct tgactgggga tattcctgct atgtggcttc gggattcgac agcccaactc
    42661 agaccctacc tgcatgtggc taaaagagat tccctcctgc gtcagaccat tgcaggtttg
    42721 gtcaaacgtc agatgacctt ggtactcaag gatccctatg ctaactcctt caacattgag
    42781 gagaactgga aagggcacca cgagactgac cacacagacc ttaacggctg gatctgggag
    42841 cgcaagtatg aggtggattc gctttgctat cctttgcagt tggcttatct cctctggaaa
    42901 gagactggcg agactagtca gtttgatgag atttttgtcg cagcgactaa ggaaattctc
    42961 catctgtgga cggtagaaca agatcataag aactctcctt atcgttttgt ccgagatacg
    43021 gaccgcaagg aagacacctt ggtaaatgat ggctttggac ctgattttgc agtgacagga
    43081 atgacttggt cagcctttcg tccgagcgat gactgctgtc agtatagtta cttgattccg
    43141 tcaaatatgt ttgctgtagt agtcttgggt tatgtgcaag aaatcttcgc agcattaaac
    43201 ctagctgata gccagagtgt tattgctgat gccaagcgtc ttcaggatga aatccaagaa
    43261 ggaatcgaaa actacgctta caccaccaac agcaagggcg aaaagattta cgcttttgaa
    43321 gtggatggcc taggaaatgc cagcatcatg gatgatccaa atgtaccaag tctactagct
    43381 gcgccctatc tgggctactg ttcggtcgat gatgaagtgt atcaagctac tcgtcgtacc
    43441 attttgagct ctgaaaatcc atatttctac caaggagaat acgctagcgg tctcggaagt
    43501 tctcatacct tctatcgcta tatctggcca atcgcccttt ctatccaagg attgacaaca
    43561 agagataagg cagagaaaaa attcttgctg gatcagctgg ttgcctgcga tggtggtaca
    43621 ggtgtcatgc acgaaagctt ccacgtagat gatccgaccc tctactctcg tgaatggttc
    43681 tcctgggcta acatgatgtt ctgtgagttg gtcttggatt atttagatat tcgctaaggg
    43741 gctcgcttta gctcaaccga ttcttatcag aatcacaagt ttacatttaa aacgttaaaa
    43801 tttaaattta gaatgaggtt ttacttcatg gaaaatgttg ttgtacatat tatctcacat
    43861 agccactggg accgtgagtg gtacttgcct tttgaaagcc atcgtatgca gttggtggaa
    43921 ttgtttgaca atctctttga actctttgaa aatgaccctg agttcaagag tttccacttg
    43981 gatggacaaa ctattgtcct tgacgactac ttacaaattc gccctgaaaa tcgcgacaag
    44041 gtccaacgct acattgacga gggcaaactt aaaattggtc ccttttacat cttgcaggat
    44101 gactacttga tctccagtga agccaatgtc cgcaatacct tgattggtca acaagaagct
    44161 gccaaatggg gtaaatcaac ccagattggc tactttccag atacctttgg aaatatggga
    44221 caagcgcctc aaattcttca aaaatcaggc attcacgtgg cggcctttgg tcgtggtgtg
    44281 aagccgattg gatttgacaa ccaagtcctt gaagatgagc agtttacatc ccagttttca
    44341 gaaatgtact ggcagggtgt ggatggtagt cgtgttttag gtattctctt tgctaactgg
    44401 tacagtaatg ggaatgaaat cccagttgac aaagatgagg ccttgacctt ctggaaacaa
    44461 aaattgtcag atgtgcgtgc ctacgcttcg accaaccaat ggttgatgat gaacggctgt
    44521 gaccaccagc ctgtacagaa aaatctgagc gaagccattc gtgtggcaaa tgaactcttc
    44581 ccagatgtaa tctttgttca tagttctttt gatgaatatg ttcaagctgt agaaggtgcg
    44641 cttcctgaac acttatcaac tgttacaggc gagttgacca gtcaggaaac agatggctgg
    44701 tacacacttg ccaacacttc ttcatcccgc atttacctaa aacaagcctt ccaagaaaat
    44761 agcaacctcc tagagcaagt ggtagaaccc ttgactatta tcactggtgg acacaaccac
    44821 aaggaccagt tgacctatgc ttggaaaaca cttttgcaga atgcgccaca tgatagtatc
    44881 tgtggctgta gcgtggacga agttcaccgc gagatggaaa cgcgttttgc caaggtcaac
    44941 caagtaggaa actttgttaa aagtaatttg ctcaacgagt ggaagggtaa aattgctacg
    45001 gataaggctc aaagtgacta tctctttact gtcattaaca caggcttgca tgataaggtc
    45061 gatactgtca gcacagtgat tgatgtggcg acttgtgatt tcaaggaatt gcacccaaca
    45121 gaaggctaca aaaagatggc cgctcttatc ttgccaagtt accgtgtgga ggacttggat
    45181 ggtcgtcctg tagaggctac aatcgaagac ctcggagcta attttgaata cgatttacca
    45241 aaagacaagt tccgccaagc tcgtattgct cgacaagtgc gcgtgaccat tccagttcag
    45301 ctagcgccgc tttcttggac aaccttccaa ttgctggaag gaaaacaaga acaccgtgag
    45361 ggtatttacc aaaacggagt gattgataca ccattcgtaa cggtgagtgt ggatgacaac
    45421 atcacagtct atgacaagac aactcacgaa gcctatgaag actttatccg ctttgaagac
    45481 cgtggggaca tcggaaacga gtatatctat ttccaaccaa aaggaacaga gccaatcttt
    45541 gcagagctta agggccacga ggtcttggaa aacacagctt gctatgctaa aatcttgctc
    45601 aaacatgaat tgaccgtgcc tgtcagcgcg gatgaaaagc tagaagaaga gcaacaaggt
    45661 atcatcgagt ttatgaagcg tgaggctgga cggtcagaag aattgacaaa cattcctctg
    45721 gaaactgagt tgactgtctt cgttgacaat ccacaaatcc gcttcaagac tcgctttacc
    45781 aacactgcca aggatcaccg tatccgtctc ttggtcaaga ctcataacac gcgtccaagt
    45841 aatgattctg aaagtatcta tgaggtggtg acacgaccaa acaaaccagc tgcttcatgg
    45901 gaaaatcctg aaaatcctca acaccaacaa gcttttgtca gtctgtatga cgatgaaaaa
    45961 ggggtgactg tatccaataa gggattgaat gaatacgaaa tccttgggga taacaccatt
    46021 gccgtgacca ttttgcgtgc atcaggtgag ctaggtgact ggggctactt cccaacgcca
    46081 gaagcacaat gcttgcggga gtttgaagtc gagtttgcac ttgaatgcca ccaagcccaa
    46141 gaacgcttct cagcctatcg tcgtgccaaa gccttgcaga catcgtttac cagccttcag
    46201 cttgctagac aggaaggaag cgtggttgcg attggtagcc tcttgagcca ttctgttctc
    46261 agcataccgc aagtttgtcc aacagccttt aaagtggcgg aaaatgaaga aggctatgtc
    46321 ctccgttact ataatatgag tcaagaaaat gtgcgcatat cagaacatca acaaaccatt
    46381 cttgacttac ttgagcgacc atatccagtt cattcaggac tattggctcc acaagagatt
    46441 cgtacagaat tcatcaaaaa agaagaaatt taatttcaaa aagtaaacat caaaagaaag
    46501 gaggggcgaa aaggtaagaa ctaactgctg atttgcccct ttttatggta aaaaaatgac
    46561 cattgcaacg attgatatcg gagggactgg gattaagttt gctagtctga ctcctgatgg
    46621 gaaaatacta gataagacaa gtatcccaac accaaaaaac ttggaggact tactagcttg
    46681 gctagatcaa cgtttgtcag aacaggatta tagtgggatt gctatgagcg ttccaggtgc
    46741 ggtcaatcaa gagacaggtg tgattgatgg cttcagtgcg gtgccctaca tccattgctt
    46801 ttcttggtat gaggcgctta gctcttatca gctacctgtc catttagaaa atgatgccaa
    46861 ctgcgttgga ctcagtgaac tactagctca tccagagctt gaaaatgcag cctgtgtcgt
    46921 gattgggaca gggattggcg gagccatgat tatcaatggt agacttcatc gaggtcgcca
    46981 cggtctgggt ggagaatttg gctacatgac aacccttgcc cctgctggaa aacttaataa
    47041 ctggtcgcaa ctagcatcaa ctgggaatat ggtacgatac gtaattgaaa aatctggtca
    47101 tactgattgg gacggtcgca agatttacca agaggccgca gctggtaatg ctctttgtca
    47161 agaagccatt gagcgcatga actgcaatct ggcgcaaggc ttgctcaata tccagtatct
    47221 gatcgatcca gatgtcatca gtctgggtgg ctctatcagt caaaatccag attttatcca
    47281 aggtgttaag aaggctgttg aagactttgt agatgcctac gaagaataca cggtcgcacc
    47341 agttatccag gcctgcacct atcacgcaga tgccaatctc tacggtgctc ttgtcaactg
    47401 gctacaggag gaaaagcaat ggtaagattt acaggactta gtcccaaaca aacgcaagct
    47461 attgaggttt taaaaggtca catttctcta ccagatgtgg aagtggctgt cactcagtct
    47521 gaccaagcct ctatctctat ccagggtgag gaaggtcact atcaattgac ctaccgcaaa
    47581 cctcaccaac tttatcgtgc cttatccttg ttggtaacag ttctagcaga agctgataaa
    47641 gtagagattg aggaacaagc agcttacgaa gatttggctt acatggttga ctgttctcga
    47701 aatgcggtgc tgaatgtggc ttctgccaag cagatgattg aggtcttggc tctcatgggc
    47761 tactcaacct ttgagcttta catggaagac acttaccaga ttgaaggaca gccttacttt
    47821 ggctatttcc gtggagctta ttcagcagag gagttgcagg aaatagaagc ctatgctcaa
    47881 cagtttgaca tgacctttgt accatgcatc cagaccttgg cccacttgtc ggcctttgtc
    47941 aaatggggtg tcaaggaagt gcaggagctc cgtgatgtag aggacattct tctcattggc
    48001 gaagaaaagg tttatgacct gattgatggc atgtttgcca cgttgtctaa actgaagact
    48061 cgcaaggtca atatcgggat ggacgaagcc cacttggttg gtttgggacg ctacctgatt
    48121 ttgaacggtg ttgtggatcg tagtctcctc atgtgccaac acttggagcg cgtgctggat
    48181 attgctgaca aatatggttt ccactgccag atgtggagtg atatgttctt caaactcatg
    48241 tcagcggatg gccagtacga ccgtgatgtg gaaattccag aggaaactcg tgtctaccta
    48301 gaccgtctca aagaccgtgt gactctggtt tactgggatt attatcagga tagcgaggaa
    48361 aaatacaacc gtaatttccg caatcatcac aagattagcc atgaccttgc atttgcaggg
    48421 ggagcttgga agtggattgg ctttacacct cacaaccatt ttagccgtct agtggctatc
    48481 gaggctaata aagcctgccg tgccaatcag attaaagaag tcatcgtaac gggttgggga
    48541 gacaatggtg gtgaaactgc ccagttctct atcctaccaa gcttgcaaat ctgggcagaa
    48601 ctcagctatc gcaatgacct agatggtttg tctgcgcact tcaagaccaa tactggtcta
    48661 acggttgagg attttatgca gattgacctt gccaacctct taccagacct accaggcaat
    48721 ctcagcggta tcaatcccaa ccgctatgtt ttttatcagg atattctttg tccgattctt
    48781 gatcaacaca tgacacctga acaggacaaa ccgcacttcg ctcaggctgc tgagacgctt
    48841 gctaacatta aagaaaaagc tggaaactat gcctatctct ttgaaactca ggcccagttg
    48901 aatgctattt taagtagcaa agtagatgtg ggacgacgca ttcgtcaggc ctaccaagcg
    48961 gatgataaag aaagtttaca acaaatcgcc agacaagaat taccagaact tagaagccaa
    49021 attgaagact tccatgccct ctttagtcac caatggctga aagaaaacaa ggtctttggt
    49081 ttggatacag ttgacatccg tatgggcgga ctcttgcaac gcatcaaacg agcagaaagc
    49141 cgtatcgagg tttatctggc tggtcagctt gaccgcatcg acgagctgga agttgaaatc
    49201 ctaccattta ctgacttcta cgcagacaag gatttcgcag caactacagc caaccagtgg
    49261 cataccattg cgacagcgtc gacgatttat acgacttaat actcttcgaa aatctcttca
    49321 aaccacgtca gcttccatct acaacctcaa aacagtgttt tgagcagcct gcagctagct
    49381 tcctagtttg ctctttgatt ttcattgagt ataaaaacaa gaacaccttg cttggcgcag
    49441 ggtgtttcgc gtgaaacaga agaattatct ggtttcaaat gctacagtta gacaaactta
    49501 tgataaaata gcagaaagtg aatgtttcct aagagcaatt ctatcgatga gcaattggag
    49561 gtattatgct acacttaaaa ttagtaaaac aagaaataga agctgaaaag ccagcatctg
    49621 tagaagcttg gatcatttcc gtcaaattta aaaaaggttg ctaccgacat atatagattc
    49681 caaaaacaaa aacgttagcg gaactagcag atgtgatttt atggagtttt gattttgcaa
    49741 atgatcatgc tcacgcattt ttcatggata atgttgagtg gagtcatgca gattcttact
    49801 ttcttagctt tgttagtgac gatgttgaag aacgttacac agaaaatgtc tatctggata
    49861 gcctaagtgt caaacaaaaa tttaagttta ttttcgactt cggtgatgaa tggcgttttg
    49921 aatgccaagt gctgagagaa atcgagacag aggacgaaga agcttatctc gtacgttcgg
    49981 ttggaacgtc gccagaacaa tatccagatt atgatggttt tgactatgaa gaatggtaaa
    50041 attgaaatct aaaaaacaat tggaatcagt ctgtgtaggc ttagtatttc a
//
LOCUS       DBEJZV010000016        48511 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.16, whole genome shotgun sequence.
ACCESSION   DBEJZV010000016 DBEJZV010000000
VERSION     DBEJZV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.16"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..138)
                     /locus_tag="ACL3S0_001084"
     CDS             complement(<1..138)
                     /locus_tag="ACL3S0_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGR1312009.1"
                     /translation="MAYSIDFRKKVLSYCERIGSITEASHVFQISRNTIYGWLKLKEK
                     TG"
     gene            complement(269..1141)
                     /gene="nadC"
                     /locus_tag="ACL3S0_001085"
     CDS             complement(269..1141)
                     /gene="nadC"
                     /locus_tag="ACL3S0_001085"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGR1312010.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1377..2687
                     /locus_tag="ACL3S0_001086"
     CDS             1377..2687
                     /locus_tag="ACL3S0_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGR1312011.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2765..2931
                     /locus_tag="ACL3S0_001087"
                     /pseudo
     CDS             2765..2931
                     /locus_tag="ACL3S0_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3053..3247)
                     /locus_tag="ACL3S0_001088"
     CDS             complement(3053..3247)
                     /locus_tag="ACL3S0_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR1312012.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRKLFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(3707..4435)
                     /locus_tag="ACL3S0_001089"
     CDS             complement(3707..4435)
                     /locus_tag="ACL3S0_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR1312013.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            4593..6002
                     /locus_tag="ACL3S0_001090"
     CDS             4593..6002
                     /locus_tag="ACL3S0_001090"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR1312014.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKEFQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKKEYGNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKRS
                     GRWYRKVSDNNGFEVEIEE"
     gene            6020..7315
                     /locus_tag="ACL3S0_001091"
     CDS             6020..7315
                     /locus_tag="ACL3S0_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR1312015.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            7320..7628
                     /locus_tag="ACL3S0_001092"
     CDS             7320..7628
                     /locus_tag="ACL3S0_001092"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1312016.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALEWIGEIR
                     "
     gene            7625..7933
                     /locus_tag="ACL3S0_001093"
     CDS             7625..7933
                     /locus_tag="ACL3S0_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR1312017.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(8800..11451)
                     /gene="adhE"
                     /locus_tag="ACL3S0_001094"
                     /gene_synonym="adhC"
     CDS             complement(8800..11451)
                     /gene="adhE"
                     /locus_tag="ACL3S0_001094"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGR1312018.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQTSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(11751..12161)
                     /locus_tag="ACL3S0_001095"
     CDS             complement(11751..12161)
                     /locus_tag="ACL3S0_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGR1312019.1"
                     /translation="MENLTNFYEKYRVYLTRPRLEILAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            complement(12163..12591)
                     /locus_tag="ACL3S0_001096"
     CDS             complement(12163..12591)
                     /locus_tag="ACL3S0_001096"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGR1312020.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            complement(12638..12937)
                     /gene="yajC"
                     /locus_tag="ACL3S0_001097"
     CDS             complement(12638..12937)
                     /gene="yajC"
                     /locus_tag="ACL3S0_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR1312021.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            complement(13054..15030)
                     /gene="tkt"
                     /locus_tag="ACL3S0_001098"
     CDS             complement(13054..15030)
                     /gene="tkt"
                     /locus_tag="ACL3S0_001098"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR1312022.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            complement(15144..16235)
                     /gene="ulaG"
                     /locus_tag="ACL3S0_001099"
     CDS             complement(15144..16235)
                     /gene="ulaG"
                     /locus_tag="ACL3S0_001099"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGR1312023.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            complement(16347..18020)
                     /locus_tag="ACL3S0_001100"
     CDS             complement(16347..18020)
                     /locus_tag="ACL3S0_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR1312024.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNESKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            complement(18199..18903)
                     /locus_tag="ACL3S0_001101"
     CDS             complement(18199..18903)
                     /locus_tag="ACL3S0_001101"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGR1312025.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            complement(18905..19768)
                     /locus_tag="ACL3S0_001102"
     CDS             complement(18905..19768)
                     /locus_tag="ACL3S0_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGR1312026.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            complement(19772..20437)
                     /locus_tag="ACL3S0_001103"
     CDS             complement(19772..20437)
                     /locus_tag="ACL3S0_001103"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGR1312027.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRRITEAADPAGAARAFKDEIKR
                     IWG"
     gene            complement(20454..20939)
                     /locus_tag="ACL3S0_001104"
     CDS             complement(20454..20939)
                     /locus_tag="ACL3S0_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR1312028.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            complement(21019..21297)
                     /locus_tag="ACL3S0_001105"
     CDS             complement(21019..21297)
                     /locus_tag="ACL3S0_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1312029.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENSLRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQAL"
     gene            complement(21320..22777)
                     /locus_tag="ACL3S0_001106"
     CDS             complement(21320..22777)
                     /locus_tag="ACL3S0_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR1312030.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            complement(22908..23531)
                     /locus_tag="ACL3S0_001107"
     CDS             complement(22908..23531)
                     /locus_tag="ACL3S0_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGR1312031.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKILDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            complement(23582..24568)
                     /gene="jag"
                     /locus_tag="ACL3S0_001108"
     CDS             complement(23582..24568)
                     /gene="jag"
                     /locus_tag="ACL3S0_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGR1312032.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            complement(24587..25411)
                     /locus_tag="ACL3S0_001109"
     CDS             complement(24587..25411)
                     /locus_tag="ACL3S0_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR1312033.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            complement(25386..25757)
                     /gene="rnpA"
                     /locus_tag="ACL3S0_001110"
     CDS             complement(25386..25757)
                     /gene="rnpA"
                     /locus_tag="ACL3S0_001110"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGR1312034.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            complement(25774..25905)
                     /locus_tag="ACL3S0_001111"
     CDS             complement(25774..25905)
                     /locus_tag="ACL3S0_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312035.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            complement(25906..27096)
                     /locus_tag="ACL3S0_001112"
     CDS             complement(25906..27096)
                     /locus_tag="ACL3S0_001112"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGR1312036.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            complement(27147..28100)
                     /locus_tag="ACL3S0_001113"
     CDS             complement(27147..28100)
                     /locus_tag="ACL3S0_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR1312037.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            complement(28161..28753)
                     /locus_tag="ACL3S0_001114"
                     /pseudo
     CDS             complement(28161..28753)
                     /locus_tag="ACL3S0_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(28856..29302)
                     /gene="comGG"
                     /locus_tag="ACL3S0_001115"
     CDS             complement(28856..29302)
                     /gene="comGG"
                     /locus_tag="ACL3S0_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGR1312038.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFSSVK
                     IKEEKTDKKEEVVTDSSEKAEKKNQKRSLKRKRIHSQFNYNALNPE"
     gene            complement(29280..29741)
                     /gene="comGF"
                     /locus_tag="ACL3S0_001116"
     CDS             complement(29280..29741)
                     /gene="comGF"
                     /locus_tag="ACL3S0_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGR1312039.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(29704..30006)
                     /gene="comGE"
                     /locus_tag="ACL3S0_001117"
     CDS             complement(29704..30006)
                     /gene="comGE"
                     /locus_tag="ACL3S0_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGR1312040.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(29969..30403)
                     /gene="comGD"
                     /locus_tag="ACL3S0_001118"
     CDS             complement(29969..30403)
                     /gene="comGD"
                     /locus_tag="ACL3S0_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGR1312041.1"
                     /translation="MINKILVKSLKIKAFTMLESLLVLGLVSILALGLSGSVQSTFAA
                     VEEQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLPVPKGIQAPSGQSI
                     TFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(30366..30689)
                     /gene="comGC"
                     /locus_tag="ACL3S0_001119"
     CDS             complement(30366..30689)
                     /gene="comGC"
                     /locus_tag="ACL3S0_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGR1312042.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQDDGRITEEQAKAYKEYHDKQNTS
                     QIVKD"
     gene            complement(30691..31707)
                     /gene="comGB"
                     /locus_tag="ACL3S0_001120"
     CDS             complement(30691..31707)
                     /gene="comGB"
                     /locus_tag="ACL3S0_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGR1312043.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMKSLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(31655..32596)
                     /gene="comGA"
                     /locus_tag="ACL3S0_001121"
     CDS             complement(31655..32596)
                     /gene="comGA"
                     /locus_tag="ACL3S0_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGR1312044.1"
                     /translation="MVQEIAQEIIRSAREKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYGNLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(32672..33037)
                     /locus_tag="ACL3S0_001122"
     CDS             complement(32672..33037)
                     /locus_tag="ACL3S0_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGR1312045.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(33188..34246)
                     /locus_tag="ACL3S0_001123"
     CDS             complement(33188..34246)
                     /locus_tag="ACL3S0_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGR1312046.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(34409..35560)
                     /gene="nagA"
                     /locus_tag="ACL3S0_001124"
     CDS             complement(34409..35560)
                     /gene="nagA"
                     /locus_tag="ACL3S0_001124"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGR1312047.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(35713..37530)
                     /locus_tag="ACL3S0_001125"
     CDS             complement(35713..37530)
                     /locus_tag="ACL3S0_001125"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGR1312048.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(37631..38773)
                     /gene="tgt"
                     /locus_tag="ACL3S0_001126"
     CDS             complement(37631..38773)
                     /gene="tgt"
                     /locus_tag="ACL3S0_001126"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGR1312049.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLSSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            38903..39760
                     /locus_tag="ACL3S0_001127"
     CDS             38903..39760
                     /locus_tag="ACL3S0_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGR1312050.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(39787..40404)
                     /locus_tag="ACL3S0_001128"
                     /pseudo
     CDS             complement(39787..40404)
                     /locus_tag="ACL3S0_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(40511..40879)
                     /locus_tag="ACL3S0_001129"
     CDS             complement(40511..40879)
                     /locus_tag="ACL3S0_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGR1312051.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            complement(40890..41314)
                     /locus_tag="ACL3S0_001130"
                     /pseudo
     CDS             complement(40890..41314)
                     /locus_tag="ACL3S0_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            complement(41637..42779)
                     /locus_tag="ACL3S0_001131"
     CDS             complement(41637..42779)
                     /locus_tag="ACL3S0_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR1312052.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDVQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAKKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVAERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(42945..43565)
                     /locus_tag="ACL3S0_001132"
     CDS             complement(42945..43565)
                     /locus_tag="ACL3S0_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR1312053.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(43569..44849)
                     /locus_tag="ACL3S0_001133"
     CDS             complement(43569..44849)
                     /locus_tag="ACL3S0_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR1312054.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(44910..46394)
                     /gene="thrC"
                     /locus_tag="ACL3S0_001134"
     CDS             complement(44910..46394)
                     /gene="thrC"
                     /locus_tag="ACL3S0_001134"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGR1312055.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(46470..47747)
                     /locus_tag="ACL3S0_001135"
     CDS             complement(46470..47747)
                     /locus_tag="ACL3S0_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGR1312056.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VEERFSIYMEAIQKKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(47854..47937)
                     /locus_tag="ACL3S0_001136"
     tRNA            complement(47854..47937)
                     /locus_tag="ACL3S0_001136"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(47901..47903),aa:Leu,seq:caa)
     gene            complement(47947..48018)
                     /locus_tag="ACL3S0_001137"
     tRNA            complement(47947..48018)
                     /locus_tag="ACL3S0_001137"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(47984..47986),aa:Gln,seq:ttg)
     gene            complement(48029..48101)
                     /locus_tag="ACL3S0_001138"
     tRNA            complement(48029..48101)
                     /locus_tag="ACL3S0_001138"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48066..48068),aa:His,seq:gtg)
     gene            complement(48116..48186)
                     /locus_tag="ACL3S0_001139"
     tRNA            complement(48116..48186)
                     /locus_tag="ACL3S0_001139"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48152..48154),aa:Trp,seq:cca)
     gene            complement(48191..48271)
                     /locus_tag="ACL3S0_001140"
     tRNA            complement(48191..48271)
                     /locus_tag="ACL3S0_001140"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48235..48237),aa:Tyr,seq:gta)
     gene            complement(48284..48356)
                     /locus_tag="ACL3S0_001141"
     tRNA            complement(48284..48356)
                     /locus_tag="ACL3S0_001141"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48321..48323),aa:Phe,seq:gaa)
     gene            complement(48360..48433)
                     /locus_tag="ACL3S0_001142"
     tRNA            complement(48360..48433)
                     /locus_tag="ACL3S0_001142"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48397..48399),aa:Met,seq:cat)
BASE COUNT        14438 a        10612 c         8654 g        14807 t
ORIGIN      
        1 tcctgttttc tcttttagct ttaaccagcc ataaatggta ttacgtgaga tttggaaaac
       61 gtgtgatgct tctgttatac tacctattcg ctcacaataa gagagaactt ttttacgaaa
      121 atctattgaa tatgccataa gaagattata ccacattgtg tactattttt ggttcatttt
      181 actatatttg aagaggcgtt taaactatct gacataaaac tcgttctaga ggaaagacat
      241 cctttaaaaa gttagtttat tttacaactt agacatcaag gtaggttaac cccttcatgg
      301 aaaaatcaag actcttagca ctatgggtta aactaccact ggagacgtaa tcaatcgcta
      361 aaccacgaaa acggctaata gtggtcatat caatatttcc agaacattca atccgagaac
      421 gtcctgcaat tagggtaatg gcctgttcaa tctgttccaa tgacatatta tccaacatga
      481 taatatcagc acccgccgcc gcagcttctt cggcagcagc aaggctttcc acttccacct
      541 cgaccatttt cacaaaaggg gcataggcac gcgcttgagc aattgccttt tgaacactac
      601 ctactgccgc aatgtgattg tcttttagca ggatagcatc tgataaatta aagcgatgat
      661 tatagccacc gccaactctc acggcatatt tctcaaaaag acgtaaatta ggagtagttt
      721 ttcgagtatc aaatacctta atgcaatcat cgcctaaggc ttctacataa gcagctgtca
      781 tcgaagcaat ccctgataaa tgttgtaaaa aattcaaggc aacgcgttca catgttaaga
      841 gacttctcac cgagcctatg atttctaaaa ccaaatcgcc actagtcaaa cgatccccat
      901 ccttaaattg atgaggattc tggaaggtca cctcggcatc aaatagggta aaaacccttt
      961 gaaaaacggt tagccccgct aaaacaccag cttccttggc aaaaagcgac accttggctt
     1021 ggccatgatg atcaaaaatg gcattggtac tgtaatcttc ggaatgaaca tcttctcgca
     1081 aggctgcttt caatgtatca tctatttgaa aaggggttaa atcagttgaa atgattgaca
     1141 tcactaggtc ctctattttt aatatcactt gtaagcatta gaggcaatca ctattaactt
     1201 ccataggaaa tcacaagcct gaatacctca tttttaattc taacaagtgt caatacaatt
     1261 gtcaagacaa ttgtattttt ttgtgtataa tagtcaagta ccaataggaa acaggtggtc
     1321 ttttgagcgc caaaattgcc aacctatttc catattctaa ctgaaaggac aattcaatga
     1381 ttcatttaat aatgattagc gccattgctc tagccattgg aattggttac cgcaccaaaa
     1441 tcaatattgg cctgctggct attgcttttt cttacctcat cgcaaccact ctcatgggat
     1501 taagccccaa agaacttctt catttttggc caacctcact cttttttacc atttttagcg
     1561 tctctctctt ttataacgtt gcaacaacta acggtactct tgatgttttg gctcaacaca
     1621 ttctctaccg cacacgcacc caccctaacg ccctctacat gattttatac ctgatggcaa
     1681 cccttttgtc tgctttaggt gctggatttt tcactactat ggccgtttgc tgtcctctag
     1741 cgattaccct ctgtcaaaaa gcggacaaac accctttgat tggagctcaa gccgtcaatt
     1801 ggggagcttc aggaggggct aatttgataa ccagtagctc aggcattgtc tttcaaggcc
     1861 tgtttaagca aatgggatgg gaagagcaag ctttttcact tggcaatcat atctttatcg
     1921 tcagcattat ctacccactc atcgtcttgc ttttattatc ctgttacagt cactatagta
     1981 agggaagaac aaactcatcc ttgactattg accaaccacc actcctcagc aaggttcaaa
     2041 gacaaaccac cttgctcatg atcagcagca tggttttggt ttggcttttt cccttgttgc
     2101 atctcatttt cccaaacatc gcctggatag ctacttatca aaaaacattt gatattggct
     2161 ttgtctcaat actcatggtc tgcctcgcct taaggctcaa attagggaag caagaagcca
     2221 ttttagctaa ggttccctgg gctacaatta tcatgctctg cggcatgagc ttactaatgt
     2281 ctctagcggt caagtcaggt ttagtcacac tgatagggca cctcatgaca acaaccattc
     2341 ctcatttctg gttacctctg ttcttttgtg tgatagccgg agtgatgtca ctctttagtt
     2401 ccaccctatc cgttgtagct ccagccctct ttcccatcat tgctatcatc agtgctcaaa
     2461 atcctcagat tgatattcac ttactcacaa cagccaccgt tattggcgct ctatctacta
     2521 atatctcacc cttttcatca gctggttctc tcattcaact ctcacttccc aatatagagg
     2581 aacgtggcct tgccttcaaa aagcaaatta ttctgggtgt ccccatcagc ttaagtttgg
     2641 gactcttgac cacctggatt ctcatccttc tagcttcctt aagttagatt tattatctaa
     2701 cttaagggtg gacttggtat aataaagtag acacaaaatt aagtgcaaac gaggaaaagt
     2761 cattatgcca agaaaaacct ttgataaagc cttcaaactc tctgctgtaa atctcatcct
     2821 gtaaaaatga ttagttcaac tttaaaaatt catcccaata gtctttatcg atggattcaa
     2881 gaatatgaaa aatatgaaga aagtgcgttc ccaggacatg ggagcgcact tcgtcatact
     2941 caatttgaga tgtagtaaaa taaaataaga ccaggacaaa tagatcagga cagtcaaatc
     3001 gatttctaac aatattttag aagtagaggt gtactattct agtttcaatc tactatagta
     3061 aagttgactt tcctgtacca tttttaccag taattaatgt cacgtctgaa ctcgaagtat
     3121 caaaagaaat attatcaaac aatttacgat gatccaccct atacgaaata ttttctactt
     3181 tcattttttc tccttttgaa ctaatagcaa aagaaacagt tctgttttca tactctttcc
     3241 ccttcatcta tattattcgt aatgaaaaat aaaaaaataa aattttttta aatgattatg
     3301 attcagaatt tatttaatat attaaaataa tatataagta aataaattgg gagattgaaa
     3361 ttcatttcta gcaatttgtt agaagtcaca gtctactatt ctaaccacag tatactatat
     3421 gtgttacaag aaaagactca aaaacttctc gtcagtgtaa gaatgtttga aacactattt
     3481 aaaactaaat aactataaga agtagatcag gtgaacaatt tcagtaccta ctctataagc
     3541 tatacgaaga tatttttcaa catgatggat acaacgatca ctcttttaaa gccatcttat
     3601 ttagaaaaga gaaaccattt aagcatagat gggaccttct tgccctgttt taaatttttc
     3661 ttaaactaga gtctgtaaaa gattggcttc attttcacat tttctcctag gaggaatgtc
     3721 gtaatgcaaa agaattaaat tcaaataaat catagcgatg acgactaatc gagtactcaa
     3781 acggagttcc gttatccaaa taagccactt gttctacttc aaataccggt tccgttggaa
     3841 ggagctgcaa gtaatgttgc tcattttctg aactagaaga agctcgcaag atttttgtag
     3901 cactggcaat atgcaatcct aactttcctt caatgtaatt gtaaatcgat ttttgtaaaa
     3961 tatcttcagt aatacctgga ataacatcgg tactcatata agtttgttcc agaacataag
     4021 gtttaccgtc aataatacgc aggcggtaaa tattataaac tggactctgc aaagcgacct
     4081 gtagtttttc tgctaaaaat tcatttgcaa attctaattt gaagtgaata atcctcgagt
     4141 caattgtaga atgagcatct tcagatattt ttgtcaatcc ccggatatct ctttctggaa
     4201 cgattaattt tctttttgag ctgccacgag agagaacaaa ggttccctgc ccacgttttc
     4261 taaaaattaa gccctcagaa actaacaagt ctaaagcttt tttgatcgtc attcgactac
     4321 aggcaaactg tttagctaat gtcatttcat caggcaattg ttcgttcatg gtatatttat
     4381 tacaaagaat cttttcacga atctcattgt aaataaataa atattttgta ctcatttaat
     4441 ctggttctct ctataatatt ctaatagtag tataacaaag ttcaagaaat gaggcaaaca
     4501 caagatatgt atcaacaatt tttaaaaatg tctagacaaa ttttaaaatt atgctatact
     4561 ttatgtacag aataatagaa aggaggttga gcatgaaaaa aaagttagta tttcctaatc
     4621 tgttttggtg gggagctgct tctagcggac ctcagacaga aggtcaatat ggaaaagtac
     4681 atgaaaatgt gatggactac tggttcaaaa cgcatccaga agattttttc gataatgtcg
     4741 gacctcttgt agccagtaac ttttttcata cttacaccga agatttccac ttgatgaagg
     4801 aaattggagt taattctttc cgcacttcca tccaatggag tcgactcatc aagaatttag
     4861 agacaggtga gcctgatcca aaaggtattg ctttctacaa tgccatcatt gaagaagcta
     4921 aaaagaacca gatggatctt gtgatgaatt tacatcattt tgatttacca gtggaacttc
     4981 ttcaaaaata cggtggttgg gaaagcaaac atgtagtgga gttattcgtg aagtttgcca
     5041 agactgcttt cacatgcttt ggagataagg ttcattactg gacaactttc aatgagccaa
     5101 tggtcattcc agaagcagga tacttatatg ctttccatta tccaaatcta aaaggaaagg
     5161 gaaaagaggc cgtacaagtc atctataatc taaaccttgc tagtgcaaaa gtgattcaac
     5221 tatatcgctc attaggactt gatggaaaga ttgggattat tttaaacttg acacctgctt
     5281 atccaagaag taattctcca gaagacttag aagcaagtcg atttacagat gacttcttta
     5341 acaaagtctt cttgaatcca gctgttaaag gaactttccc agaaagattg gtaaaacagc
     5401 tagagagaga tggcgtgtta tggagtcata ccgaaaaaga gtttcaactg atgaaatcaa
     5461 atacggttga ttttcttgga gtaaactact accatccaaa acgtgttcaa gcacaagcaa
     5521 atcctgagga atatcagacg ccctggatgc cagaccaata cttcaaagag tatgaatggc
     5581 cggagcgtcg catgaatcca tatcgtggtt gggaaatttt tccgaaagcc atttatgata
     5641 ttgctatgat tgtgaagaaa gaatatggta atattccatg gtttatcagt gaaaacggaa
     5701 tgggtgttga aaacgaagca cggtttatcg gtgaaaatgg agttatcgat gacgtgtatc
     5761 gtattgaatt ttatgaagaa catttaagat ggctacataa agccattgaa gagggaagtc
     5821 actgttttgg ataccacgct tggaccgcat ttgattgctg gtcttggaat aatgcatata
     5881 agaatcgtta cggatttatc tccgttgatt tagaaacgca aaagagaacc atcaagagat
     5941 caggaagatg gtatcgcaaa gtaagtgaca ataacggttt tgaagtagaa attgaggagt
     6001 aaagagagga gatattcaga tgaaaaactc aaaatttata gatcaatttg ccacctttgc
     6061 tggtaaacta gggaaccaaa ttcatttaaa aaccctaaga gatgcattcg taacagtaat
     6121 gccattatat attttggcag gtttaatcgt tcttttgaac aacacggtat ttaagtggat
     6181 tttccaaggg gatacattaa caagattcca atattgggga ataacaattg caaacggtac
     6241 tttaagtatt tcaggtatga ttattgctgt aatggttggt tatttcttag ctaaaaacag
     6301 agatttcgaa aacccgttag cagcatcaat gctatcatta gtttctttaa ttgtgatgat
     6361 gccaaataca gtttctgtag ttcctgacgg agcaaaagat gcggtaaaca tttcaggtgt
     6421 tctttcattc aacaacacag gtacaggcgc aatgttcgcc ggggttatcg tagcgattat
     6481 tgcaacagaa ttattcattg aattatcaaa cgttaaagct ttacaaatga accttggtga
     6541 aaatattcca ccagctgtta gtagatcatt tagcgtatta cttccagtca tgaccgtcat
     6601 ctccttattt ggggttgttt cagcattatt attcaatata actggaatga acttaatctc
     6661 aatcattaca atctttattc aagaaccaat tcgtcatatt ggtacaagct taatcggggt
     6721 cattattatt tactctttag gaaatatgtt atggctattt ggtattcacc aagcagttat
     6781 ttacagtgcc atcctagaac cattactatt aattaacatt actgaaaaca tcactgcagc
     6841 aaataatgga caagccattc cacacatcat caacttatca caaatacaaa cattcgcttt
     6901 aatgggtggt agtggatcta cattatgttt attaatagca acattcttag taagtcgcaa
     6961 tgctgtttct aaaaacgtgg ctaaattatc ttttggacct ggtatcttca atatcaatga
     7021 accagtatta ttcggttacc caatcgttta taacatttca ttagctattc catttatcac
     7081 agttccagta cttggtattt taatcagcta cttagcaaca gttacaggat tcatgagtcc
     7141 tgcatttata caagttcctt ggactacacc agtattctta aatgcatggt tagcaacagc
     7201 aggggacgtg agagcagttc tagttcaatt catcatcttt gcacttggag ttcttctata
     7261 cattccattt atcaaagtta atgacaaagt tgttgaacaa gaaatggaag gttaagatta
     7321 tgaaacaaat tttattagta tgtaatgcgg gaatgtcgac aagtatgctt gttaaaaaaa
     7381 tgcaacaaag tgcgactgaa cgtgggattg aaatttctat ccaagcaaaa tcaatgacag
     7441 aagctaaaaa aaatatccat gaagcagatg tcattctaat tgggccacaa attcgttatg
     7501 agttacttgc tgtgaaagaa attgcaggaa atatccctgt agataccatt gatatgcggg
     7561 attacggaat gatgaatgga gcaaaagttc tggaacaagc acttgaatgg ataggagaaa
     7621 taagatgaca gaagaaatgg aatatatctg ttttcagctc attgccaata gtggagcagc
     7681 caaatcatcc tttattgaag ccatccaact agctaaggca ggaaatttaa aagaagcgaa
     7741 aattaaagtt gaagaagcgg aagactcctt agtagaagcg cacaagattc actccaatct
     7801 catacaaaaa gaagctactg gagaaaaaat aggattctcc ttgctattta tgcatgcaga
     7861 agaccaaatg gcttcaacag agattattca gttgctatct aaagaattca tcgatctcta
     7921 tcaaaataaa taggaacact gtcgttccca tctgtcttta ttaatgacga ctacattgta
     7981 ggaacctcca aaagttggac aaaatgattg aaaggattgg atcctgcatt acacaagatc
     8041 caatcctttt cttttactct agtttttata atatgttgaa tctagaatag tccactgcag
     8101 tttctaaaaa attgctggaa atagatgtta agctccaatt tatttgttta tatcttattt
     8161 cagtttacta tactagctta ttattctagt gaaaaattga atgagccact atttatttaa
     8221 tatgtatgat gagggaatga ctcaaaaact tcttgtcgat ataagaatat ctgagatagt
     8281 attttaaaac gaaaggacta taaaagctca tttccttcgc acttatttta tagagatcta
     8341 tcattatact ctttagaaat caaaaagtaa cacaccttgt catcgtttta tcgtaaatct
     8401 gttaatgagg gggctagtct tatctgcaat ctcaaatcag tgttttgagc tgaatggcac
     8461 tcgttttcta gtttgctctt tgattttaat tgggccttag taaatactac tcttaaatta
     8521 aactatagtg aattgaaata agatgtaaac aactctatca ggaaactaaa attaatttct
     8581 ataaatgttt tagaagcaga tgtgtactac tctagtttca atctattata tattttgttt
     8641 ctattctagt ttttcaaaaa gggcaaaaag gcctcaatat cataaaaagg catcctatca
     8701 ggtgttcaaa aaccttgata ggatgccttt tatcatagaa aaattactgg atctttccct
     8761 caaattgagt ttttgtcttg cttctagact gataaacaat tatttacggc gtcctggtct
     8821 ttctttgtag ccatagtatg catcttcgat gatttcttgc atatggtcta ccattggaag
     8881 acgtgggtta gctggtgaac attggtcttc ataagccagg aaggctaatt cacgagaatg
     8941 ttctttccat tctttttcgt caattccttg gtctctaaaa ttcatttgga tcccaatacg
     9001 ttcaccgagt tcgtagacag cttttgcgta agattcaacc ccttcttctg gagtagaagc
     9061 tggaagtcca agcatgcgtg cgatatcttg gtatttttca tctgcacggt agtagttgta
     9121 cttaggccat gttgctgtct tagctggacg tgtaccgttg taacggataa cgtatggaag
     9181 caagatagca tttgtacgac cgtgtattgt gtggaattgc gcaccaatct tatgggccat
     9241 tgagtgagaa atacctagga aggcattggc aaaggccata ccggcgattg ttgaagcgtt
     9301 atgcattttc tcacgtgagt ggaagtctgc attcttaact gagctttcga gattttcaaa
     9361 gaccaattta atggcttgaa gtgctaaacc atcagtgtag tcactagcca tttgtgatac
     9421 gtatgcttct gtcgcgtgag tcaatacgtc cataccagta tcagcagcaa caaatcctgg
     9481 aactgtcaat accaaagcag gatctacgat tgccacagtt ggtgtcaatg agtagtcagc
     9541 gattgggtat ttacggttgt ttgctttatc agagataacg gcaaatggtg ttacttcaga
     9601 tcctgtacca gatgtagttg gaatcgcgat gaatttagtc ttcttaccaa gcaatgggaa
     9661 cttgaaggca cgtttacgga tatccatgaa tttttggaca aggtcacgga agtccacttc
     9721 tggttgctcg tagaagagcc acattacttt ggcagcatcc attggagacc caccaccgag
     9781 tgcgatgatg gtatctggtt tgaaggcacg cataatctca gtaccacggt ttacagttgt
     9841 gatatctgga tccggttcta catccgcaaa gatttggtaa acaaccttat tgcgacgaag
     9901 gtccagttgt tcgatgatac gatcaaggaa accaagctct accatggcat ggtcagtaac
     9961 gatcatgaca cgttcaacgt cacgacattt ttgaaggtat tgaattgaat cacgttcaaa
    10021 gtatgttttt gaaggaagtt tcatccattg catgttattt ctccgtcttc cgactttttt
    10081 gatattcaag aggttaatgg cactaacgtt atccccaact gagttgcgtc cgtaagaacc
    10141 acatccaagt gtcaatgatg gcaagaaggc attgtaaacg tccccgatac caccaaaagt
    10201 agaaggtgag ttacagataa cacgaatagc tttaacagct ttaccaaatt ctttagtcaa
    10261 ttcttcgtca gctgtgtgga tagctgctga gtgtccaaga ccgttaaatt caaccatttg
    10321 acgagcctta gtaataccat cttcacggct ttcagatttc aaaactgcaa taactggtga
    10381 caatttttca cgagtcaatg gctcattttc accaacttct ttacattctg cagcaagaat
    10441 gtttgttcct tctggaactg taaatcctgc ttgttctgca atccaagttg ctggtttacc
    10501 aacgatgtca gcgttcaatt ttgcaccagc acagtttttg ctgtttgctt tgacgccgaa
    10561 gcagaactct tcaagaagag ctttttcttt tttgtttaca aagtaagtgt ggtaagattt
    10621 gaactctgct acaaattcat cgtaaatttc tttatcaatg ataactgctt gttcagatgc
    10681 acagaccata ccgttatcaa atgatttaga catgacgata tcgtgtgctg cttgacgaat
    10741 gtttgctgat ttttcaacat aagctggaac gtttccggca cctaccccaa gagctggttt
    10801 accacatgaa taagccgcct taaccatggc attaccacct gttgcaagga ttgtcgcaac
    10861 accttcgtgg ttcataaggg cacttgttgc ttccatagat gtttgagtaa tccattgtac
    10921 acagttttca ggagcaccag ctgcgatagc tgcatcgcgg acgatacgag ctgcatgagc
    10981 agatgattct tgtgctgatg gatggaaggc aaagacgatt gggttacgtg tcttcaatga
    11041 aatcaatgat ttgaagattg ctgttgatgt tgggtttgtt gttggagtaa taccacaaac
    11101 aacaccaact ggttcagcaa taagagtcaa tcctgttaca tcgtcttctt cgataacgcc
    11161 aactgtctta gtgtggcgca tgttgtttac tacgtgttca caggcaaaca agttcttagt
    11221 tgctttgtct tcaaatacac cacgtcctgt ttcttcaaag gcatgtaaag ccaattctcc
    11281 gtgggcatcc aaagctgcta ctgatgcttt ggcaacgatg tagtcaactt gctcttgatc
    11341 caatttacgc atttcttcaa gggcaactag agctttttga accaactcat ctacgtgttt
    11401 ttcagcaacg agtttctttt cctctggtgt cacagttttt ttatcagcca tattttcctc
    11461 catagctttc aaggaacgat atcctttgtt aattttttca caagtttatt ataacgcatt
    11521 atttcaactt tgtaaacagt ttcataaaca tttcacaaag aatttttaaa ctcttgtgaa
    11581 acttttctca ttttcttttc ttatcaggtt ttatctttga agtttgtgaa atttatttca
    11641 aatatttttt atttcacaaa cttggttgga agagggattt ggaaagaaag gaatttgcag
    11701 gtaagcgctt accttgcgat tctaataata cctcctttga taaggaggct ttatttttgt
    11761 tgaaaaacgc cttgtttaaa agttccttca taaacgactt cttgttctgt tgttagtttc
    11821 ccttttcctt cagcctgacc atttacaaaa tcaccttcgt aggtccagcc ttctttagat
    11881 tgaaaggtac cttttccgtt gaaggctcca ttgttgaagc cacctgtata ttggtctcca
    11941 ttttggaagg taatggtacc ttggccattc attttaccgc ggacaagact gccatcataa
    12001 acaatcgttc cattatcgag ttttaagaca ccttttcctg gaatatttag aaaaaagacg
    12061 agtacagcac agaaaacaat ggtaactact gccaaaatct ctaaacgtgg acgagtcaga
    12121 taaacacgat acttttcgta aaaattcgta agattttcca ccttaactct ccttttctaa
    12181 acgttctaac caagcttgac agccctcttg aacacgtcga taggtttctt caaaatctcc
    12241 tgtataccaa gggtctggaa cactttcaga tgaaaatgag taaatcttat cttgacagtc
    12301 tactggacac atctgacgta agtcggaaac atttgaagcg tccattccga taatataatc
    12361 aaaggcttca aaatcttcct tactaatctg aagcgatgtc ttgttcttgt cataaggaat
    12421 ctcatactgt tgaaaaattc cctgagtccc cttatgaatc ggattgccat gttcccaaga
    12481 ggaagttgct cgactttgga tttcgtagtt atctgtcatt gatttcataa caaactcggc
    12541 catagggcta cggcaaatat ttcccagaca gacaaagact aattttttca tcccatttcc
    12601 tttcttttat agaaaaacgg gagttcgtga tcccgtctta tttttcaatt gcgccttcta
    12661 gtgaagctgt ttctttcagc ggtaatactg tcttgatagc agctagttca aaagtcaagt
    12721 aaactccatc tacgtcaaga actattgttc ccttctccgt atctacttca tcgactgttc
    12781 cataaagtcc accgattgta atcacttcat agcctttttg tagtttattt aagctttcca
    12841 tacgcttttg agcttgtttc ttttgagaac gttgcataaa gaacatcaag gccatcatac
    12901 ctacaagcat gattaaaaaa gtaatatttg gattcattgt tttctccttt gtcttttaca
    12961 taggactact atatcaaatt tcagctactt ttacaagatt gtaccttact tttctggtaa
    13021 gaaaaaccag agcttacgcc ctgattttta ggattatttc aagtttcgaa caatttttac
    13081 aagattttct acagtaaagc catattctgc caatactttt ggtgctgggg cagaggctcc
    13141 gaaggtatca atacctagaa cggcaccatc gagaccaaca tatttgtacc agttttgact
    13201 tgcacccatt tcgactgcaa cacgacggcg gactgcattt ggaagaatct cttccttgta
    13261 agctgcatct tgtttatcaa agacatctgt agatggcatg ctgactacgc ggattttttc
    13321 gccttgacta gccaattctt tagcagctga gacagcaaga ttaacctctg aacctgtcgc
    13381 aatcaagatg gtatcaaagt cggctgcatt ttcatataca acataagcac ctttagcaac
    13441 cttgtcgaag tctgttccat cttcaacagt caagttttga cgtgtcaaga caagggcagt
    13501 tggtgttttc tcacttgtca ctgcaaggta ccaagctgct tgcgtttcac gcgcatctgc
    13561 tggacggaaa acatttagat ttggcatagc acgaagacct gctaaatgct caactggttc
    13621 gtgagtcgga ccatcttccc caactgcgat tgaatcatgg gtaaagacat aagtcacagg
    13681 aagtccttgt aaggctgaca agcggacagc tgccttcaca tagtcagaga agacgaagaa
    13741 agttccaccg tatacacgaa gtccaccatg aagggccatc ccgttcaaga ttgttcccat
    13801 tgcaaattca cgaacaccaa actgaatgtt acgattcaag cgattggcat cgtcttgaag
    13861 tccatccgtc ttgatataag tcatgtttga gtgagcaagg tcagctgatc cacctaggaa
    13921 ggttggtaat ttagctgcca caacattcaa ggcatcttga cttgaattac gagttgcttg
    13981 agaaaaacca ttttctaaag ctgggaagtc tgctggagtc acttcgactg gatcacgtcc
    14041 gtcgatgatg gcttctactt ctgcagccag ttctggatga gcttctttat aatctgcaac
    14101 taatttagtc caagcttgat aagctgatgc gccacggtct gcaacatgtt ctttgaaatc
    14161 agcatatact tgttctggaa tttcaaatgg ttcgtagtcc caaccgaggg cttgacgagt
    14221 tgatgcagtt tcatctgctc caagaggggc gccgtgtaca gcattagttc cttgtttgtt
    14281 tggagaaccg tatccaataa ccgtcttcac ttcaatcaaa gatggcttgc ctgaagcttt
    14341 tgctgtttcg atagcagcat ggatggcttc caagtctgtt ccattttcaa ccaaggcagt
    14401 atgccaaccg taggcattgt aacggtcacg aacactttct gtaaaggaat cctttgtctc
    14461 accatccaag ttgatatcat ttgaatcata aagaacaacc aacttatcaa gtttttgcaa
    14521 acctgcgtat gaagctgcct cgcttgagac accttccatc aagtctccgt ctccacagat
    14581 aacgtaagta tagtggtcaa agatattgta gccttcacgg ttatatttgg ctgccaagaa
    14641 acgttctgct tgggcaaaac cagtagcagt tgaaatccct tgccctagag gacctgtcgt
    14701 agcatcaatc cctgccgtat gaccaaattc tgggtgacct ggtgtttttg aaccccattg
    14761 acggaaactc ttaatctcat ccatgctgac atcttcaaaa ccagaaaggt gaagaagagc
    14821 ataaaggagc attgaaccat gacctgctga aagaataaag cggtcgcggt taatccagtt
    14881 tggttgagct ggattgatat gaagttgttt tgtaaagagg ctgtaagcca tcggagccgc
    14941 tcccataacc acacctggat gacctgagtt ggctttatta atggcgtcaa tacctagaaa
    15001 acgaattgca ttaacagata gatttgacat agaatttcct ttctatttga ggtgattatt
    15061 gaatcacaca ttctatttta ctattatatg aaaattatcc gtatcatgca acatacggat
    15121 aacctccaaa gaatattttt atattatagc aaagctttaa attgaatgtt agagtcttgt
    15181 tcaaaacaat catcaaaacc acgtggatga tggtattcta ctaagtgttg atcttgagga
    15241 taagtgtact taccgccaac ttcccagata aatggatgga aatcgtattg caagcgatct
    15301 tttcgcattt tccaaagttc tagaatctca ttagtagaag ccatgaagtt agaccagata
    15361 tcatagtgaa ctgggataat gactttggta cgcagatttt ctgccatacg aagaaggtcg
    15421 atagatgtca ttttgtcttg gatacctacc ggattttcac catagttatt caaagcaaca
    15481 tcaattttaa agtctttacc atgttttgca aaatagtttg agaagtgaga atctgcacca
    15541 tgatagatgg ttccacctgg tgtttcaaag atatagttaa cagccttttg agccatttct
    15601 tcatctgtaa cagccaagcc agcaagttca ccgcctgtct catcagcacc gttcactggg
    15661 agagttacca agcaagtacg gtcaaatgat tctactgcat gaatcttcat atcttttaat
    15721 tcgatagtgt cacctggttt aacaacgatg atacgttctt ttggaacacc ccatccttcc
    15781 cagattcgtc cacagtggta aggaccgata aacttaacat gctctaactt aggattgttg
    15841 agaattgctg cagctgtgta tgggtcgata tgatcactgt ggaagtgtga aactaagtaa
    15901 tagtctagtt cgttgatagc aaatggatcg ataaccattg gctgaacacg caagtttggt
    15961 tgcaacttac gaacacctgc catatttgcc atttggtgcc cacgaaccat atctttcact
    16021 tttttggttg attttccacg atttgaccaa aggtccatga caacgttagc accagctggt
    16081 gtcttaatcc aagtaccaca gttgcctagc caccacatgg caaagttgcc ttcaggtacg
    16141 acttcttctt cgatttcttc gttcaaccat gttccccact ctgggaaagt ggctaaaatc
    16201 catgactctc ttgtaatttc tttgacgttt ggcatatgtt gcctcctttg gatataattg
    16261 ttatctttga gattagtata ccacccttca aaacactaaa aaagaccaag aaaaacacag
    16321 gtttgtgttc atcattggac tgtccttcaa atatcttcca aaaaagcttg aactactatt
    16381 tcttgattta taagtgtttg aacctcttct tggaacttac tagccaactt gctatctaca
    16441 atataagacg aaataagact agaaagattt tcactgaaac ttttgctctc attacgaaat
    16501 atattgtgtt taagatagtc tagcattttc aaaatatctt ctgcttcaag gataggatta
    16561 acccttaaaa tcggaaatct gctatccaaa tcatcattag tagtaatcac tacatcaact
    16621 tgtgcaatat cttccacact cttaaattgt tctgttgtaa atacagtgtc aatttgctca
    16681 tttggaaaat aaagtttgca ttgtttcagc aaaagtctcg aaaccgcaac accttcatca
    16741 caaacgagat aaactttttt catatttttt tgagacgatg gtgtatactt taaaaatcct
    16801 ccaatatgaa tcgtcaaata ggcaatatca tcgtctgtta gccgaataaa ccatgctcct
    16861 tctaaaattt ccgcagattt tctagtgact aaaaataatt ctccatactt ggatcgaatt
    16921 tgttttgtta gaggattttt agaaaaaata ccgtaagtct ttctaaataa caaggcttta
    16981 cagtggatca tcaaatttcg taacaaatca tccttgttct caatctccat tcggatttgt
    17041 gattcaaaat accagataaa ttcttctaaa gcaagtttta attgccgaaa atcatcactt
    17101 tctgcatgaa tatccaaatc tttacgatag gagaggagga gaacagctac aagagaaact
    17161 tcaagtcctg acaaagaaat ttcaaacttt tgaaacaacc gttctcctag cttcttagac
    17221 acctgatact ctattctttt tcttatcaaa gaaaattctt tctctatatc ctgatgtctt
    17281 tcttgatact gttcaacatt atgacagctt aacagcaaat aaggtagaac ctgcaacata
    17341 aaagttattt catgatggtt tattttcttc cctaaatctt gttcaactaa aggaacctgt
    17401 tccttaaaaa attggttcat ttcaacagaa agcaaacact catcatctaa cctctctttc
    17461 atcttatctt ctaaaataga tacaaaagtg gcattttctt ccataaaaat atgatataga
    17521 agcgattgaa gatactgaat tttattaaga gggtgggcat gaaggtggta tccctgtgac
    17581 ttgctcactt gcaagatcac ctgatattgt tccaaagtta gttgataacg aatactattc
    17641 aaatcattga gaacagtatt cctagatacc tctgttaact ctatcaattt ttcaatcgta
    17701 atacgttctt tagaaatacc tatccatagt aacattatca tcatacgttc atgcgcactc
    17761 atgatataat cgtacgaatc tacttccgat aatagtttac aacaagcatc tctctgctct
    17821 tccgttaagt gaataccaat tcgtggaata ctaatgatgt gaagcgcctc gtcacccaga
    17881 gcagcattga ttttgtcaat gtgataataa attttccttc ttgactcttt caaatctttc
    17941 gaaatcgcca taatcgtttt ggacgtttct tgatccatca aatattgaag caaatcacaa
    18001 cttgccttat ccagtaccat attaaaaaat cccccaaatc tattgatatc acagcaattc
    18061 tttttatttt accatatata tatcaagcgc tatttctaaa aaatctttta aaattacttc
    18121 aattccaact ttactctcaa taaaaatcaa atgtaaaaag aggagctaaa tttatctttt
    18181 tctcctcctt catcgttctt acttttgacc ataataagca tttggtccat gtttacgttg
    18241 gtagtgtttt tctagtatgt actggggagc aggtccaact cttggattga tttgttctgt
    18301 aaagcgattc atctttgata cttcctctag tacgacagag tgataaacag cattctctgg
    18361 atttttgccc caggtgaatg gaccgtgatt gcgtacaaca attcctggta cttcaaccgg
    18421 gttaagtccg cgatgttcaa actcttctac gataaccagg ccagtatctt tttcataggc
    18481 cacttctact tcgtccttgg tcaaactacg ggcgcaaggg attgaaccgt agaaataatc
    18541 tgcatgggtt gttccgtaga aaggaatatc acgacctgcc tgagcccaag caacagcttc
    18601 tgtcgaatgg gtgtgaacca cactaccaat ttctgaccaa gccttatata attgcacatg
    18661 agttgggagg tcggaagatg gtcttaaatc cccttctagg atcttaccat ctagatcagt
    18721 cactaccatg ttttcaggtg tcaattcgtc ataatccacg cctgatggtt tgataacaat
    18781 gacaccgagt tcgcgattaa cttcagatac attcccccag gtaaatttga caagtccatg
    18841 ttttggcaat gattgattgg catcacagac tcgtttacgc atagcattga ttacttgatt
    18901 catcttacat caaacctgct ttcttaatga gtggatagag aaaagcttgc gcctcttgaa
    18961 cggctgcgcg tgtttcttct actgtttcac aattttcaga ccacatttcg attaggaaag
    19021 gtccattata attggtttcc tttaaaatat cgaaagcttc ttcccatttg acacaacctt
    19081 gcccgaaagg tacatctcgg aactggccct ttgaactttc tgtcactgca taagtatcct
    19141 tgagatggag agctgcgatg gcatgatgac caagataaaa ctcactatag atatcattat
    19201 gccatgcaga cacattacca atatctggat atacaaagag gaagggagag tcaatctctt
    19261 tttctatagc caaatatttt tcgatgctat tgatgaaagg atcatccata atttcaatag
    19321 caagtaccac ctgagcttct tcagcccagt cacaggcttt tctcaaattt ttgataaaac
    19381 gttggcgtgt ctggggtgac ttttcctcat agtaaacatc gtaaccagct aattgaatcg
    19441 tacgaactcc caagtcttga gctaattcga tacatttttt catgagttct agagattttt
    19501 cctctagaac tggatctttt gaacccaatg ggtagcgacg atggcctgaa aaacagatag
    19561 aaggaatacg aacaccagtt tcatagattg ctttgacaac ttccaagcgt tcttccttac
    19621 tccagtcaag tcttgctaaa cgctcgtcac gttcgtcaat agacatctcg acaaaatcaa
    19681 agcctaactc cttggcaaaa tttaaacgtt ctagccaagt aaagtgtgtt ggggttgcct
    19741 tttcataaat tccaattgga cgtaccatga tttaccccca aattcgtttg atttcatcct
    19801 tgaaggcacg cgctgctcct gctggatccg cagcctctgt aattctacga cctgcgataa
    19861 aggtaaagac atcaacacct tcaaagagtt tgagagtatc tacatctaga ccacctgtta
    19921 cagatacacg gaagcccatg tcaatgagtt ttttaacctt attaaggtct ttttcacccc
    19981 aagtttcacc agcaagaaga gcatcacgag attggtgata aatagcttgt gagatacctg
    20041 catctagcca aagctgagct tgttcaaaag tccaatcgcc ataaagctcg atctggattt
    20101 cgcctcgttc tcctcgttca gtcttgatag cctttagagc tgcttccata gtagggatgg
    20161 ttgcacaaca gatacaagtc atccagtctg ctccacgaac cgcattattt ttagcaactg
    20221 ttccaccagc atcagcacat tttgtgtctg ccacaataat cttatctggg aaaaggctac
    20281 gcaagacttc agccagttca cttccaactt gaagcaagca aacagttcca gcttcgataa
    20341 tatctacttc ctgaccaaca gaaacagctg ctttaatcgc tccttgcaag tctgaatggt
    20401 ctaatgcaac ttgtaaatta ggtattcttt ttgtcatttc tttattcctc tttctaactt
    20461 tccaaatcca atccttcgag ataagggcta tccttagatt cttcaatcat agccaagaca
    20521 tcttctttag tctggcaagc ctgtaaacgt gcaatagaat cttctaattc aaacagggca
    20581 ataatttgtg gaatggccac acttgtgtga atttttgaac ttgttgctgc tagtgccaac
    20641 aaaacagata cctctttccc atctgaaaat acaacaggat tttgtaaggt aatcaatgaa
    20701 aaggcatcac tttgcacacc agcttcaggt ctagcgtggg gcatagccat acctggcatc
    20761 aagatatagt aaggcccata ctcttcagtc gattcaatga tagcatcgta atactctggc
    20821 aaaattgccc cactttcaat caagggatct actgctacct tgactgcttc tttccaatcg
    20881 ttagcctcta aacctagtcg gatcgagtcg ttgtcaatta aagcttgttt taaattcata
    20941 tctgcctcct ttatttaaag agggagaagg acagaaacga taactctcag tttctgtcca
    21001 gtcccctcca accttttact atagtgcttg actgagtttt tcggtgattt ctttatcatc
    21061 catcaagtta tcaagaccaa ttaacttccc attagttcgc ccttccaatt cttgaatcaa
    21121 atgaagagaa gcgattacga tgtcatatcc tactgctaaa cctttagctt caccgacact
    21181 gcatgaattg actgtaaaat ctgtttgatt aagcttacgg agagaatttt caaccttcat
    21241 cttgataacc attgatgaac ccattccatt tccgcacgct gctaatactt taaccatttt
    21301 atttctcctt ttctagatac taagcttctt cttgaacttc accgttgtaa tatttctctt
    21361 tatcttttgc tttggcaaat tgaagttgag gaataacaag caagaagaga cacacaagta
    21421 cataaccaac aataccaagg tatttgaaga tatatccaaa tccaagccat gggaattcaa
    21481 agtcgatatt tccatggtag ccaccataag atgccaaatc gagaagggcc acacaaagag
    21541 ctcctagagc aacttgaagg acacctgata taaaggaaag gataacagcc gctttccatc
    21601 cgccgcgttt atcagcgtag accgcaatgg ctgcattgtc aaagaacact ggtacaaatc
    21661 ctgtaataat aagaatcgga tttttaaaga cgatgagcaa gacaattgta atcaattgac
    21721 caatcaaacc aaaggtaaat cctgacaaga cagcatttgg agaaccaaat ccataagaag
    21781 ctgcaacgtc aaccgctggg aatgaacctg gcaacaattt gtttgaaata ccttggaaag
    21841 cgtttgttaa ctcagatacg aacattcgga caccttgcat caaaacgaac aagtaaactg
    21901 agaaggtaaa ggctgtttgg ataatgtaca taaagaaatc ttgtttagca ggattgaata
    21961 gagttcctga agtgatgact tctttattag acataatgtc tggacccaag attaaaagaa
    22021 tggccccgaa gaatacgagc atcaaggtag cagatgcaac aactgtatcg tggaagattg
    22081 agaggaactt aggtaattta agattgtcta aactttcttc tttcttacca aagcgtcctg
    22141 ctactttatc tacaaaccag attgcaaatt gctgttggtg accaatcgca aatccgccac
    22201 caccagtcaa gcgttgagtt gcctcaacag tcatatttga actaactgcc cagtaaagtc
    22261 cacagatgat accaatcgct gctgtaccgt aagcattgcg caattgtggt actaagaata
    22321 gaaccataag agatactgtt gcagcttgtt gtaccatgat gtgaccagta ataaagaggg
    22381 ttcttacctt cgtaatcttt cgaagagcta cgagcaagat atttattccg aaaccaatca
    22441 atagagctgt agttgcagtt ccaacaaaat ctggaaactc tgctgcaatt ttgttgtttg
    22501 ctgcagcaag tccaaagtaa gggtcgataa ccgctgcacc aatttggaat ttgtagttaa
    22561 gagctgctaa gattggacga aaggttgtaa ccaaaccacc agcacccacg ttaagcaaca
    22621 tataccctac tgttgcttta acaaaccctg aaaaaacgtc atgggcaggt tttttcaaaa
    22681 gtgcatatcc tatcaacacc aataaaccta cgaaaaatgc gggattctgc aaaatattgc
    22741 tagaaaacca atttagaaca cttgaaacga cttccataat tgttctcctt ttgaattgtt
    22801 tttgtaagtt tattatataa tgcgaaagcg caaacaaaaa gaccaagaat tacacagcgg
    22861 actgttcact cttggactgt atgatttatg atgttttaca aattatctta ttttctcgta
    22921 gctagataat agggaagaat tttagaataa gacttcaata agccttctac gatttcttct
    22981 tcagacgaat tttctgtcat aggaacatct accttcacta aaacttttcg aacttcttga
    23041 cttctcacct tctcgcgtaa agtacgacgc ttttcttcat tcgcctccca ccgttgactt
    23101 tgaccattag agtaggttag ataataaatc cctttaacgg ttggaatgtc taaaatcttg
    23161 gcctgcttgc ccagtgtttg ctcatccttc ttacgttcga tgaaactgac ttccaaagaa
    23221 attccaaagt cagtagatgt cccatacaaa cgtaaggcca tcataggttc tgtcacttgt
    23281 ccgtctctct gtagataaac ccaaaaatgt ggtctcaaac gctgggcctg attcatccac
    23341 tgactagtct gttggagttg ccattctgga tggcttgctt gaaaggcttt ggccagttct
    23401 gtaaaagcct ttcgggcctc ttgtcctttg tggcggaacg ccagcatctt ctctcgctct
    23461 gctcccgctt tatcaggact acggtactgc aaaccagaaa agtctagata gtctcttatc
    23521 ttattcaaca tcagtttaac ctcctctagc tagcaaaaaa tcaggtcaac cctgatttta
    23581 cttattctgt atctacaacg acatagcgat ttggctcatc accttcagag taactggtca
    23641 cgccatccat acgtgaaata atacggtgga taatcttgcg ttcactattc gacattggat
    23701 ctgtttgatg actacgtcct tcttctaaaa cacgaatcgc caatttttgc gcataggtct
    23761 gcaagacttc tgcacggtgt tcaacataat cattgacatt aatagtgata tagaaggttc
    23821 ttgaatagca gttgtaaaga taattttgag ccaacagttg caaggccttc aagactttac
    23881 catggtagcc gataatacga cctggttcgt tagtatcaat ttgcaaattg atgctacgac
    23941 ggttataatc atttgaaagt gtagcctcaa catccatgtc atcaataatc gtttgaacat
    24001 aagcagtcac atccgtagcc acctgggcaa tatcataact ttgctcgacc ttcaagccca
    24061 tctctttcaa gtcttgattt tcagtttgat cttgctcagt ttcaaggtca tcagcgcctg
    24121 cttcttccct catcgcttcc tcgatttgaa gttcatttaa aatctcaatg tgaccagttt
    24181 cttctaagat agtgctggca tgtctttcat gttttaagat ttcagccttg acttcatcag
    24241 aaataccttg accttcttcc tctatttttt taatagcatc aaccacatga ccaaggtcaa
    24301 cggtttcttc actaacagtc ttcacaggct cgttcaaatc attgattttt ttcggaacgc
    24361 cttttactac ctgttgattt gctttgacaa cagtcgtttc actaatcgct tcaatatcca
    24421 cttgggctgg ttttttacca aatagaccaa gaaagccttt tttctcccta gaaatgactt
    24481 tgatatgagc cttcattctt ggaatatcta attctttcaa tcctttctgg attgcttctt
    24541 caacagttga acctgtaaat actaccatta ccagattcct ccttatttat ttcgttttct
    24601 gagccttttt cttggctttt ctttttctat tttccaaatc tttttgtgcc tgtactacgg
    24661 cctcgcgctc tgcgataatc ttgaatggat tattcaagaa ataggtttgc aagacttgat
    24721 aagcattaga cactgtccag tatagggcga ctccacctgg cgcataaact gcaaagataa
    24781 aaatcaagac tggaatccca tacatcatcg cagtcgtagc gccatttcgc tcagacaaag
    24841 ctttgttgga caaccaagta cttaaaaagg tgaatactgc tgctaaaatc ggaagaacaa
    24901 gggttgtatc cacactacca aggttaatcc ataagaaatg acctgtcttt aaaaagtcaa
    24961 ctcttgatag ggcttggaac agggccaaaa taaccggcat ctgaatcaaa atcggccaaa
    25021 gagagtctga ctgtctgaca cccatttctt taaatacttt acgcatttcc tgctctagtt
    25081 tggttctgct ttccatatct cgacctggat attgttctcg aagcgcctta atgcgtggct
    25141 gagcttcctg cattttccta gaagccacca tttgcacctg aaagactggc aagaggactg
    25201 tacgaatcaa gaccgtaaag agaataatcc ccactccgat actaatatca aacgataaaa
    25261 agcgaatgat ttccgcaaag aagtaaacca atttactcca aaaatcagcc gattcggctg
    25321 taatatcgct agttacccca ttagtcgcac aggctgtcat gattaacaga gacagtccta
    25381 gcaaactagt caactttagt ttctttttca ctcccatttc cttcccggta aatctttgat
    25441 aattttaata catggagtag atttttctcc atctctgcgt atcccaaggt ttcgactcct
    25501 tttcgagcaa tgacaacaaa gtcgacatct tctaccagac tcccttttgc attctggata
    25561 atatgccgaa tccgtcgctt aatttgattt ctagtgacgg cattccccag ttttttgcta
    25621 actgatagac ctactcgaaa atggtttttc tggttttcta attggtagac cacaaatttg
    25681 cgattagcaa aacttgtccc ctccttgaaa atcgccttaa aatctttctc tctttttaca
    25741 cgaaagtttt tcttcaaaac tcaactccat ctattaaatt actactatta taccatattt
    25801 ttcaaaaaag ccaatcatag caaggttttg gacaatttca tcagaaaaag aagctggaaa
    25861 aataactttc ccaactcctt gtattgaata tttttttagt ttcacttatt ttttcaagcg
    25921 ttcaacgtca cgggcaatga ctaattcttc atctgttgga ataaccaaga cacggatttt
    25981 agctgcctct gttgagatgt ctcctgtaac gccaaagaca ttcttttcat catcaacatc
    26041 acaaccaaac cacgaaatcc ctgagattac atcacgacgg aaattctctg cattttcacc
    26101 gacacctgct gtgaaaacaa tggcatctgc tccatttagc actgcaaggt actgaccgat
    26161 atgtttttgg atacggtcaa catacatttc ataagccaag ctagcctcgt gattcccttc
    26221 tgctacagct gcttctatat cgcgcatatc gctagaatta gcagaaactc ccaaaagacc
    26281 tgattcacgg ttaagaacac gactgatatc ttctggtgtg ttaaaatcct ctgtatattg
    26341 cattaaataa ggaatgatag ctggatcaat atcccctgta cgcgttccca tcataatacc
    26401 accaagagga gtgaacccca tagaagtgtc tacagatttg ccggctttca cagctgtaat
    26461 tgagcctccg ttaccaatat gacaggtaat taacttcaag tcttctaatg gacgtcccaa
    26521 gagttttgca gcttctcctg ctacaaactg gtgacttgta ccatgagcac cgtatttacg
    26581 aaccttgttt tctgtgtaat attttgttgg tagagggtag cgataagctt tctctggcat
    26641 acttgtgtgg aaggaagtat caaaaacaac tacactggta atgtctggca acaattcctt
    26701 gaaggcacga acacctgctg cattggccgg gttgtgtaga ggagccaaca aactcaactc
    26761 ttcaactttt tctaaaacat ctccctcaac aactgttgat tctttgaaat attctccacc
    26821 agcaacaaca cgatgtccaa cacctgtaat ctcgtcataa gccttgataa tatcgaaacg
    26881 aatcaagtca tccaataaaa ttttaacggc ttgtgtatga ttttcaatat ccaaaatttg
    26941 ttgttcagaa cggccgtcaa attttacagt tgaaattgaa tctttcaaac cgatacgttc
    27001 aatcaaacct ttcgccaata ctttttcttc tggcattaag tataattgcc atttcaaact
    27061 tgaacttcct gcattgattg caattgtttt tgtcataaca tgatacccct ttttaagcgt
    27121 tttcaactat tataacaaaa tctattttat atttcagtac cttgagtcca tttttgaaaa
    27181 ttttctttaa atttcattaa aacacttgca tcttgcaagc tagcaagtgg ataaacaaaa
    27241 ggctctactg ctatttcatt tttcttctgt aggataaaaa tagtcttaga ttgtttagca
    27301 ttagcaaaga gattttcagg cagactaatc atagcaacca gactcgcctc ttctttcagc
    27361 cattctttta acaaatcact ttgaggactg gtcaacaaat cactcggagc tagaaaaata
    27421 gcgtatccgt ctgacttgag gtacttaagc ccttgttcca tgagcaagtg atgggcgtaa
    27481 gtatgttctt ggctagaagc aacttgatgg cgcgacgcaa cggcatcatc aggataatag
    27541 ccaacaggca agtcactgat gaccacatcg ctttctttga gcatttgtgg acgaacggca
    27601 tctccttgga caaagccagc ctgcaaacca attacatctg ccatgctagc tgccagatca
    27661 atcagtaaat catccacttc cattcccaag taatccacct ttttatcaag cgaggtcaag
    27721 aaagtagcgc ctagaattcc catcccagaa cccatttcga ggatagtaat ttcctcctct
    27781 ttaaacaact cttccacaat aaacaccaaa agcaaagcaa tagcatccgg tgtaaactgg
    27841 tgattggcct gcaagggttc tgtttgccca gccttcatca agagaaactg gtaggtcttg
    27901 agccattctt ctttgcgtag tgctaaacgc ttaagggcct gattgttgtc tttgacctgg
    27961 tttagctcag tttcaccatc cagatagatg ctgttttgct ccaccaaggc gtcataaaag
    28021 ttggtcgcca aatcactttg gatgacttgg acattctcta gtaaataggt ataagcttgt
    28081 tcaatttttt caaaatccat attcctatct tatcaaattt cccttctttt ttccatcctt
    28141 atagaaaaat cactccctga ctaggcgagt gatttttggg ctactattaa aaagaattct
    28201 gagtgatttc cttgaaacag gtcttcagcg ctatagagaa tctgactatg cacagatgaa
    28261 aaaccatgct caattagctt gttttccagt tcagctaaat caaatccatg atgattagct
    28321 tctgtcttgg taaaatcagc aatgatgagt ttcccatctt ccttcaaatg ttgatgaaac
    28381 agtgagagag ccgcatccaa atcaggcata tgatgaagaa cccgactaac agcaaggcaa
    28441 tcaaactctt tctccaaggg atttttcggt aaatcttgct ccaaaaactg gatattcttg
    28501 attgcttgct gctccacttt caaacgagct tgctccaaca ttttctcaga aatgtctaca
    28561 agagtgactg acttagcctg cttggctagg ggttaggggc aaggctaata gacccgccac
    28621 caccgaaatc taaaatttct ttgtctgata gaagatcaat ctgtttctcg gctgcttgac
    28681 ataccaagtt tgcgaggaag atatttttag gggaatcgaa agtttctgct ttgtggttaa
    28741 aatcatgttt catatcttta gtttagcaca aagtatagta aactgaaata agatataaac
    28801 aaatgaattg gagattaaca tccatttcca gcaattttct agaaactaca gtggactatt
    28861 ctggattcaa cgcattatag ttgaattgac tatgaattct ctttcttttc aggcttctct
    28921 tctgattttt tttctccgct ttttcgcttg aatcagtcac tacctcttcc tttttatccg
    28981 ttttctcttc tttgattttg actgaagaaa acagaaactc atattgactc ttatccgtac
    29041 gaaccctcgt cactaagcca gttttcttgt tttgatagct tacctgacct agattaaaaa
    29101 cctgttcccc actttcttgc tcaaccttat ctttggttcg tttagccata gcaaaagcaa
    29161 ccaatttttc tttattcaaa gcatagtctt gatagtgggc gacttgtcgg ttcaagtaaa
    29221 attgcaacaa aagactaaag atagctgcca tggtgactgc atagaggaga acacctgcct
    29281 taactttctt ctttttccac acgatagatg aactcccttt ctaagccttt ttgaaactgg
    29341 aaacgaaaat gaaccagttg attgtcctct gtaatctgag ctgatttgag gccataaacc
    29401 ataggctgat acccccgtcc actagcatcg gttttacgaa aatcgtctga ctttgactta
    29461 ccgatggcga tgtccttgcc atcttgcttc atgtataggc gattgccttc tactttttcg
    29521 aactgcgaac ggtctaattc tacctcaagt tggtccacaa acaagagcca ctccttttgc
    29581 tcgctttgtt gctggtagcg aacttctgaa atgaggagct gactcatagc ttgaaaaagg
    29641 agtaatcccc cactgatgac aatgagggca agcagggatt ctaacaaggt aaaagccttg
    29701 accttatggc tctttgattg ccaacaactg ttctgaacca tggtagacct ccaatccttt
    29761 ttcactagaa aatacctgaa tctcaactcc gttgatgctt acctgatttt gccccgtctg
    29821 caaggccatc ttagctaccc tcaagacttc ttccttttgc aagatttttg cttcctcttg
    29881 cctatttttt tgaatttgtc ccaaaaggag ggtcgcaatg ctggcaaaga tagctagagc
    29941 gactactgct tccagtaaaa tcactgccct aattttttgt ttccttaatg cgtttaattt
    30001 ttccatttcc tagatataat tgatagcgaa tcgctccttt actggtctga aattcaacct
    30061 tagccaggga cgaattgccc ccagcacggt caaatgtaat actttggcct gatggggcct
    30121 gaattccttt agggactggc aacttttgac tgccattgct aatcatctgc ccatccaagt
    30181 tcagactagt cttttgttga ctagctacac tgcgtttttg ggtttcccga tagagttctt
    30241 caaactccat aaagaaaatc tgttcctcta ccgctgcaaa agtggactgg acagagccgg
    30301 acaagcccaa ggcaaggata ctcacaagtc ccaaaaccaa gagactttcc agcatggtaa
    30361 aggccttaat ctttaacgat ttgactagta ttttgtttat catggtattc tttataggct
    30421 ttagcctgtt cttccgtgat gcgtccatcg tcttgtaact ttcttaggct agcatcttca
    30481 ttcttttcca agctataaag ttctgcctgg ctttccacca ccttaacaac agctgctttt
    30541 cctttgtcat tgactgcttc tttttgcttg gtcagattag gtacaaagag caagaaaagc
    30601 acgctgataa tcagcaagac caccaacatt tccaccaatg taaaagcttt aaccttagct
    30661 tttttcaaga atgtcatcat ttttttcatt ttaaaaattt acctccatat tttgatacat
    30721 gggcatgagc attgccgcat aaagtaaaac gataatcagt gccacaaaaa taaaaaccag
    30781 tggctgcacc aaattcatgg tgcggttgac tcgggtaaaa aaggcttccc aagttttttc
    30841 agcatagatt tccaactcac tacccagctt ggacttaact tccccatact ctatgatgag
    30901 actcaattcc ttcctaaaga aaggataggt tcctatcgtc tgagaaaatt cacggccatt
    30961 tttcagggtt tgagccagat cttgaccgat ttctttaaag agctgggaac cttgttcctg
    31021 catcatttga aaaatctgcg tcagctccat tccctgtgaa atcatattcc cccattcacg
    31081 tgcataatag gctgtcaagt aggtctgcac aaagattcca ataaagggaa ggcgtgctaa
    31141 gatagaaaag acactcatct tagaacttct tttataaaaa gttagtgcta aaagggcaag
    31201 cacggaaaca agccctacca tgcctagaaa aatttgtggc agattaccga taattcgggt
    31261 ggcaatattg ctactatcca gttgtgggag caggtaattc cgtagcccca gcataattaa
    31321 gagaagaaaa aacagcaaaa tcaaaggata ggtcgctact tcaattaatt ttttcttgac
    31381 cttggccaga ttgtctagat actcttctat ctttcccaaa ctcaggtgga gattaccatg
    31441 gacttcagct agggataact gagtgacaat agcacttgaa catcccaaac ttttcatcat
    31501 ttctgagaat gatttcccct gagacaagcc cacacgcatc tgggtcacac actgcttgtc
    31561 caacaaagca ctcctatcta aaaaggagat agtctccacc agatgaaaac cgctagaaaa
    31621 gagattgtta aatagggtga tgatattttt ttgcttagct gtagctaatt ttttccgtct
    31681 cagcctgaag acttgtgata tgtccatctt taagaagctg gtcaatttgc tcattccact
    31741 tggctgcttg gtgttcttga taatctctgc ttgcaaagtc aacgattcct cctcccccga
    31801 ttaatctctg gtagcagact ccttgcagaa caactgccaa ttcttcttca ctcacaccca
    31861 actccagcag acgctcataa acacctcgga tactcttggc gtgaatggtt gaaaagactg
    31921 tcgcacctgt caaactagct ctgaccactg cacgcgccgt ctcgctgtca cgaatttctc
    31981 cgataatcaa gagatctggt cgatgacgca aggaaagttt gattagattt ccataggtta
    32041 ggccgattgc ttcgttcaac tgcaactgaa gcatgtcgtc ctgcttgatt tcgacaggat
    32101 cttcgatgga cataacttgc tgtcctttaa agagtgactt ggacaattca tgcatcaagg
    32161 tcgtcttacc actcccaacc ggaccagcaa aaagatagag tccccgttgc ctgtactgct
    32221 tgcctaattc ttcaatatcc tgaaaccaaa aatgcaagtc ctgttcctca tcgtgcaaca
    32281 aacggataac caaactctca tgcccccgat aatcgcctac agtagataaa cgtagagacg
    32341 ccatcttctg gtcataggca taatcacagg aacccagttg actacgtctt ttttctccca
    32401 cattcatacc cgccacaaac ttaaagtgac tgataacggc tgcaaacttt tcaaaatcat
    32461 agctaccaat tttacagcgc tcgtctccta ccctcatatg aagctcatag gcgtctaact
    32521 tagggacaaa ataaatatcc tgcgtccctt tttcccgagc tgaacgaatg atttcttgtg
    32581 caatttcttg aaccatactt acctcctcac ctatactatt cgcaaagagt tagaaaaata
    32641 aaaaaagcaa ctccaaaaaa gttacttttc tctattttaa tttcatacgg caagaacgat
    32701 tcctttcctg actggtttgt ttttcatagc ctgagcgtag tttttcgtct gggataacct
    32761 gctcatcctg caaaagagcc aaagaatggt attgttgtaa atactcatca cattcatcac
    32821 accagcgttg gtcttccggg tcccaaaaaa tggtcatcaa atcgcttcta cttttataaa
    32881 gaggggattc ttgttccaat ctaaaccagc aagttttgta gtatttgaga gcatcataat
    32941 actgatcaaa ttttctactt gctacaatat cttcttccca accttctaag aaccaccacg
    33001 gttcaaaatc tccgtacatt tctataacac gatacatatt cattcattcc tttgtaccgt
    33061 atattataac caattccgcc agacaaggaa agaaatatgc tcatttctga attttttgat
    33121 aaaaaatcca gccatctgat ggatgactga atttctattt acttatgtac aaaaatattt
    33181 ttactactta ggcttctgag atatcgtttt cgataatgac cttaatggca tggtggtctg
    33241 ctgccttact gaagacttcg taggcttttt caatttcact gagtttgaaa tagtgagtta
    33301 ccaatttttc tggttcaatc ttatgacttt caagtgcttt caacaattgt ggagtcgtat
    33361 ttgtagatac caaaccagtt gttacattga tgttgcgaat ccaaagttta tctaaatcga
    33421 attcaactgg tttaccatgc acaccacagt tggcaaccgt tccgtctaca ccgataatct
    33481 tttgacagaa atcaaatgtt gcaggaatac caacagcttc gatagcgaca tccacaccac
    33541 gaccatctgt caaatcataa atttctttaa tggctttttc agggtctgaa gaattaacct
    33601 tatgagtcgc accgaatgat agggcagttt ccaagcggtt atcgtctagg tctaccataa
    33661 tcaatttagc tggtgaatag aattgggctg ttaaaagagc agccaatcca actggacctg
    33721 aaccaataat ggctacgctg caaccaggtt ctactttccc ttttaagaca ccaatttcat
    33781 atccagtagg cagaatgtct gacagcataa ccaaagcttc atctgacaag tcttctggag
    33841 tatggtaaag agtattatct gcatgaggga cacgtagata ttcagcctgc ataccatcaa
    33901 tcaagtgacc gaaaatccag cccccttcgt cttcacagtg ggcataaatt ccttttttac
    33961 agtagtagca tttaccacag gcacagacgc aagaaatcaa gaccttgtca ccttttttga
    34021 agttggaaac tccttcccca acttcttcaa caatcccaat cccttcgtgg ccaagaatgg
    34081 taccactttg gcaagtagga acatcccctt tgataatatg gaggtctgtt ccacaaatag
    34141 tggtttttac aatacgcaca atagcgtctg ttggcttgcg aataactggt ttgtctacat
    34201 caacaaaaga agcaagtcct ggtttaacat aagtataagc tttcataaag cactcctccg
    34261 tttttttatt tgtactattt atagttcaat tgtaagcctt tttctttgtt tcttcaagct
    34321 ttttttgtga tttttttaac tttttattta ccagtaaagt accctgcata aaaaagcaga
    34381 agttagtctc taacttctgc tttctctctt atgcttgata acgtttcacg ccatctaggt
    34441 aggttgctac caattccaaa tctttatcta atacgatgaa gtcagcgtcg tagccttcac
    34501 ggatttggcc acagacgtca tcgatgtgaa cggatttagc tgggttgaag ctggccatca
    34561 tgactgcttc atgcggattc gcaattcccc attcgaccac attcttcaaa ccatctttga
    34621 gtttgaggat agaacctgcc aagttacctg tcgatttgag gcgtgcagtt ccatttgcaa
    34681 cgacaactgg gaattctccc aacatataat ctccgtcttc caatccccca gctgtcatac
    34741 agtctgtgat aagagcgatg ttttctgttc ctttttgttt gataagaatt tcgcaagcct
    34801 ttggatctac gtggtgacca tcacagatca actctgcata ggtatgtggc aattggtaca
    34861 tggctccaac catacccaat tcacggtgag tcaacccacg cattccattg taggcatgca
    34921 cccaaacact cgctccagca tcgactgctt ttttggcttc atcaaaagtc gcgtttgaat
    34981 gtccaagagc aaccgtcaca ccttcgcccg taactgtacg aacaaagtct tccaccccat
    35041 cacgttctgg tgcaagggca attttattaa gcaagccatt tgccgctttt tgccaagaat
    35101 gaaactcctc aacacccggg tctctcatat aagttggatt ttgtgccccc ttaaaagttt
    35161 ctgtgaaata tggaccttca taataaatcc cacgaatctt agcacctgtt gcttctttat
    35221 aatggtttcc aagattttca gtgactgcaa gcaattgctc ataagtggct gttaaagttg
    35281 tgggtaagaa actggtaaca ccggtactaa gaagtccttc actcatagta tgcaatgtac
    35341 cttcaatgtt gttgtccatc acatctacac ctgcatatcc atgaatatga gtatccacaa
    35401 gacctggggc aatgctataa cctgtatagt caatcacctc agccccttca ggaatctgct
    35461 ctacatgttt tccaaacttg ccgtccacaa gttccaagta accacctcga cgaactccgt
    35521 gtgggtagaa aaactgatcc gctttaatat agttaggcat aatgttaacc tccttaaaag
    35581 attgattcta caatttgtta tatcaattac attataaacc tttctttttt atttgtaaat
    35641 ggtatatacc tattttttgg agatatttta aaagagctgg atttctccaa ctcttctctt
    35701 ttttaataca agttattttg atttaaccgg cttgtcttga gctgtctgca aagctgtggc
    35761 aatcgtatct gcatacaatt ttgctcctgc ttcgatagtg ctactctcac tcccgaaatg
    35821 aacctgatct gttccagccc aaatttctgg atgctctttc gcaacttgat tccaatctgc
    35881 tatcgtaatg taaggtgtct tctctgccaa ttctctcata taggcagcag ccttctcaac
    35941 gatggcatag gtctcttttg tcttatctcc ctcataagga gtcaccaaaa tcatatggtg
    36001 tcccttagga agatttttca cgatactgtc ccagtcatcc ttgtagttct caggattatt
    36061 taccccagtc gcaatgacca ccgtcttagg taaaaattta ttctggctat tatttagcat
    36121 gatttcattt gcggtcttgg ttgttacgct gacctgcgcg ttaatctgtg ctccaggaag
    36181 agctgtctgt agtgctgtat ttgcccttaa agccactgag tcaccaatta acatagtgcc
    36241 atcagcaatt cccaaactgt ttgcatctgc ccgttctgcc atcaccttgg tctggccaat
    36301 atttgttgca gcttgcttca agccattgac agtcaagtct gtctcaaacg ctcccacttg
    36361 tggtgccaac aaggtcacca tgcagacaat gaaggtcaag attcctgtac ctgctgcaag
    36421 aattgcgtga atataaggca ggggacgaag ggtttggaca ataggtgtgt tcttgcctgc
    36481 aatccaaggt tccaatacat aaaatgacag actggcaaag ccataagaac aaatcagagt
    36541 cagtaataca gcaagaagat ttgatgtcaa ctgtgagaaa atgatataga aaggccaatg
    36601 gaaaagataa accgcatagc tagtatccgc taaaaagctg ataatcttcg gctcctgtat
    36661 atgatgtgtc ttttcatgta agacacgcgc cgccagaatc atggcaagag ctgcaagact
    36721 ggcaagcaag aagccgataa gataggcaaa aagataagtg aatttgacaa agaaagtcaa
    36781 aagaactagg aaaccaaagc ctcctccaaa aactaccaaa gtctttcgta aatcccagat
    36841 tttatccaac tgcttgacga gggaagtcgt ctgacgaacg cctacaatag ttgctaacat
    36901 acttcccaaa aagaatggat agacatgagt taaactggag aaataaacag aggaataaga
    36961 ggtcactaga aaactaccaa taaacatgga gaagaaactg atcaagaagg cagtagcaga
    37021 taagagaaag atcatcccct tcaactgacc atttgattta gcttgtttgg ataagaacca
    37081 aactgccaat ccccaaagaa tatagtagtg aacctcaact gccaaactcc aattatgaac
    37141 aaacaaatga ggaatgaact gagattcata actcccacct gttaagagtt catagaagtt
    37201 ggtcataaag cctaagacgc ccgcaatctg gccaccaatt ccagcaacat agtcttggcg
    37261 aaccaagaaa gtaaaaggca tggtcaccaa gaccatcaaa accacaggtg gcacaatccg
    37321 ataaaagcgt cttctaaaaa atcctatcaa atcaatctca ttgttcttag aaaattcttc
    37381 aatgagtaga gctgtaatca ggaaacctga aaatgtgaaa aagacatcta ccccgaaaaa
    37441 tcctccagga aagatcgtct gaaagaagtg atacaagagt accaaaagta aacctataat
    37501 cctaatcaag gaaaaccatt taatgcgcat acgagtttat tcttcctttc attgtacact
    37561 ttattctatc aaaaaaagaa gaaaaatcct aagagaaaac ttaggatttt tagcttatat
    37621 caattccatt ttagaaatta cgtcctgact tattatagcc atatttttcc acaaaatact
    37681 tacggaattc caagagattg tcatccatga tggcttgtcg cacttgcttc atcaggttaa
    37741 gcaagaagta aagattgtgg tagctagtca agcggatacc aaaggtttca tcagccttga
    37801 gcaggtgacg aaggtaagcg cgtgtatagt tattacatgt gtagcaatca cactcaggat
    37861 ccagtggcgt aaagtcctca gcaaactggg catttttcac aaccaaacgt ccttgactgg
    37921 tcatacaagt cccgttacga gcaattcgag tcggtaagac acagtcaaac atatccaccc
    37981 cacgaatgac cccatcgatc aagctatctg gcgctcccac acccatcaga taacgaggtt
    38041 tattttcagg cagcagttga gttgtaaagt ccaagaccgc attcatctct tcatgggttt
    38101 ctcccactgc caaaccaccg atagagtagc ctgagaaatc catgctgaca agatcgtgag
    38161 ctgattggcg gcgaaggtct tcaaatcctg caccttgcac aattccaaac aaaccttggt
    38221 catgtggacg acggtgagcc ttcaaaccac gctcagccca acggctggta cgctcgatcg
    38281 atttcttaac gtagtcataa ggttgataaa actgaggaca ttcatcaaag gacatcatga
    38341 tgtctgaact cagattattc tgaatagaga tggctttttc tggggatagg agcatcttag
    38401 aaccatttag atgattttta aaggttactc cttcttctgt gatattacgg ctatctgcta
    38461 aagaataaac ctgaaaacca ccactatctg tcaagatagg ctggtcccaa ttcatgaact
    38521 tgtggagacc accagcgcgt gcaatgagtt catctccagg gcgaagccag agatgatagg
    38581 tgtttgatag gataattccc gaacccatct ccttcaattc ttcaggtgac tgagttttga
    38641 cagtggcttg tgtcccaact ggcataaaca taggtgtcgg aaaggtaccg tggggagtga
    38701 tgatttctcc tagacgagct cctgtgtgtt tttctttctt aatcaaacga tatttgattg
    38761 gtgaatctga cattttttac ctccgaagct gggaaagaca gtcccagttc atacagtgtg
    38821 cccaaggaca cactgtatga ttttatcaaa aaaagtagga actgtcacga actatgtata
    38881 agaactatgg tataataaga gaatgaacta tccaaaaatt gatttaaaaa caattcgtca
    38941 ggagtcaaaa cattttcagg ctgacacccc ccgtctcttt ctcctctata tccttcccag
    39001 tatgctggtc atcttatctg gttttcttaa tcccttatct cggatccacg ggactgtttt
    39061 agaacagcca tttttcagca tacttggcca aatacttcaa acctacctct ttcctctact
    39121 agtctccttt atcgggacta ttcttttgac cagttccgtc tatgcaacac tgacactcat
    39181 gaaagattct aaaacggagc catctgtaaa aaacagccta gctctctttg atgaggagcg
    39241 cttttctcaa acctttttga ccctacttct caaacgtttc tatctctttt tatggagtat
    39301 ccctaattta cttgggattt acctcctctt ttatagtagc tttttagcca aaaaattcgt
    39361 caccctacat cctgagtttc caaatctaga tctctcatca gttgaaaccg agcgtttcct
    39421 catggtcttt ggactctact ttcttgcaag tctcatcttg atcattgtag gaaatatcct
    39481 ctatattcca cagtattatg cctattcaca ggtggaattt cttctctgtt atagtttaga
    39541 cctaggacag gtcccaccaa gacgaatcct aaaaactagc cgttccttta tgaagggcta
    39601 caagttccag cactttgtcc tagatttaca gcttcttcct tggtacttcc tcaattggat
    39661 tacctttggc attgctagtt tttcactcct accttatatc caatgcacta aaattatgtt
    39721 ttaccgagca gtattggctc gaaaacgtcc aaaagcttga aggttttccc ctcaagcttt
    39781 tttctatcaa tgaatttctc cgcctaccaa cttgagttcc tgatctccat gttctatcat
    39841 agcgccgatt gctgcttcta tccctcgccg aatatccact aaactcatag ttggagtagt
    39901 cggtctgttc accacctgtt ccatcatata aggaatatgc ataaaacctg ccttaacata
    39961 tggaaatttc ttttctacca aatagagagc ctgatacatc aaatggctgc agacaaaagt
    40021 ccctgccgta ttggaaacag aggccggtaa tccttatttt ttatagcttg aaccatcgct
    40081 ttaatcggca aactactaaa gtaggccgaa gcaccatctg ggcgaatggg acggtcaatc
    40141 ggttgattat cttcgttatc agaaatgcgt gcatcgtctt gattaatggc cactcgttca
    40201 ggtgtcaaac tagttcttcc accagcttgc ccaatacaaa ggacaaagtc aggttgataa
    40261 cgattcatct cttcttccaa tacttgagca gatttgtgaa aaactgtcgg cacctctagc
    40321 caacggacct cagcaccatg gatttcagct ggtaaacctt taatggcctc aaaagggctc
    40381 aaaacctgtc actaatactt tcatttctaa ctcctcaaaa ccaattcaat gaaacttttt
    40441 tcttaaaaac aagtataaca tatttccctt attctggatt aaaaaggatt agcgagatta
    40501 gaatcgacct tcaagtgtat ttaaagagta aaatactaat caaggccaaa atagctgatc
    40561 caccttgttt caaaataatt tttttatccg ctgttaaaga gccgtaagtc gcagcaccaa
    40621 tcacaaataa gacaaaaata gtcacaattt ctaaattctg tgagaaataa atgacataca
    40681 agagaaagac tcctagcaga gccttataaa tcccttgatt tttgaacaat gaacttactg
    40741 acggatgagc caattcttcc ttttccatat taaatacacg actagtcgca tctgattgcg
    40801 tggcaatact ttccaaataa aaaatgtaaa aatgctccaa agcaacgatc gttgttaaaa
    40861 taattgtaat aattgacatc tatttctcct taaatttcta tattttcaat acccaaaacc
    40921 aatttattta ataaacggct gagttctgtt ctctcaaact ctgttaagat actttccatc
    40981 tcttccttaa ccttgatatg ttgcagaggg ggattcacca ctaactgctc cttggcatac
    41041 ttcgcagtct ctaccaacac ttcccgctga ttttcaggat tacgatgacg ctccaccaaa
    41101 ccttccgttt ccaaaatctt gaaatgccgt gtcaaagcag cctgatcaat tttcaaacgc
    41161 tcctgaaccg ccatttggtt acaaggagaa tgctccagca aaaacagtaa aatctgatac
    41221 cgtgtcaaac taatccaagc cttttttcaa acaattgcgt actcgcttgc tcagacaagc
    41281 ggagttgata cagtaaatct tgaatctcta gcatttcttc ccctctcttt ttattgattt
    41341 atcaatattt gactaatcac gtataatgca aagtaaaata gattgcaaga atgttactta
    41401 actcattaca atatggtaac ttcccatttt ccattcaaat tgatactcaa tgaaaatcaa
    41461 agagcaaact aggaagctag tcgcaggttg ctcaaagcac agctttgagg tttcatataa
    41521 aactgacgtg gtttgaagag attttcgaag agtatgacaa agaaaaaacg aacgagaatc
    41581 gctttccatc acgaaagcta gatctcattc gtcaaaatga tgttatcaag tcgggtttat
    41641 ccattcattg aaacgtgaac gtgatcatag tgattttctg tcacactacc acggtctggc
    41701 attgggttcc aagtgttagc tggcccatat ttgctatcga atggagcata gaaacgttgt
    41761 ttccagatga tgtaactaat gccacggctg gccatgtttt gaatagcata ttccgcaatc
    41821 ttatccccta attctgaacg ttctgctacc ataaagtcga tagccaaacc ttttccgtga
    41881 tctccactgt ctcctggacg ataaccacta aaggatgtaa tgccaaacaa gttagcaatt
    41941 tcttctttaa aggcagctgt ttgtggttga agacctgcat tttcagattt tgctactgca
    42001 agtccagcat aatcgggcgc agctggtgcc tcgtaagttg ttgaaattac tttcgtttct
    42061 tctggttgat aagtagaaac tgctgctgta gctccatttg atgatgctac ttcttttgct
    42121 tctgaacttg ttgtagttgc ttccactgct gatgcagctt gagggcttgc ttgtgtttcc
    42181 tgcttcttag ctggagtcgt ttcctgagga gttgcttctt caactgggcg agttgtttcg
    42241 gccgtttgct cctctgggac agaagtgccc gtagatggtg ccacttcttc agaagcaatc
    42301 actgtctttg taacttctga acttgatgct acttcttttg gagcttctgc aatcggttga
    42361 gaaaggtctg caacctgaac agtttgaaca tcaacggtca cttgattagt ggtcaaatct
    42421 gctgtcgcag ttgtcacttc ttcactagag tctgcttgag gtgtttggat ttcaacttct
    42481 gttacttctt ctgcttcatt gacagtcgtt gtcaaaacag tttctgggaa aatcaagtcc
    42541 atattagtga ttttgttcag attcgcaagc actgtgacat ctacacccaa ggcttctgca
    42601 atggtgctca aagtatcacc atactgtacg gtataacttg ttttgttgtc cgttttagtc
    42661 aaatcgtttt ggatttgctc aacactacgt gcagtccaaa gaacttcttc tgcttgagtt
    42721 gccaatactg gggcaaatga caaggctact gttgacgcta ataacattct tttcttcatt
    42781 ctttcaaatt cctttcaaat gagtacctgt ctatcataac acaaaaaatg tagaaaaaaa
    42841 gccctctcgg gcctatttaa cagaactgtc tattccttgt aacaaactag gttacttgaa
    42901 atagtttgtt aggtctctgt cacaaaactg acacaatctt tttatcactt agtctcaaaa
    42961 atacgggaaa tatctgctaa cgcttgaatc ctgtgattcc cttcataagt agactctaaa
    43021 aagttgatac tttgaatccc actattctgg gcaaattcca catccagagt ccgatcccct
    43081 atataataag tattatcaga attcaactga tacttatcta gcagataggt agccgcttct
    43141 ggacttggct tccgcacaaa gccactctga ctggttaaaa tctctgtaaa ataggattcc
    43201 acccccaagt ccttgagaat ggtaaaagcg ttgttcccct tatgagtata tataaactgc
    43261 tgaattcctg attcgtctgc ccaagctagc acctcacgcg cacctggcat caaaactacc
    43321 tgagcattct tctcagccag actctgggca cgcacctgat ttagcacctc aacatccaga
    43381 tttctatctt ctgccacccg cacaagcaaa tcttgcaccg aatacttgaa gataaactct
    43441 ctcaccttct ccttatcata aggaatagaa aactgagcaa aagtctcctc aatccctgat
    43501 aaaatcgctt cgtaagagtc caataaagtc ccgtctaaat cccaaataaa agctgttttt
    43561 tgcatttcct atcctttcaa gctcatatag cgctggtaac gatagcgtag aaataaccag
    43621 cgaaaaccat tatccaagag agaccctgcc caaataccag gcaagcccca accaagcaca
    43681 atccccatca gatatcctgt cccaatgcgg atacaccaca ttcctatact tgtcgcataa
    43741 aaagggaggc gtgcatttcc taatccctgc cagactgccg tatagatgac tgttcctgtc
    43801 gtcatagggg tcccaagtag tgaaaacagt gtcactagaa cactagcctc caccgctaga
    43861 gaatcagtcg tatagagatg agttaatggt acacccaaga catatatact aaaggacagg
    43921 ggcaacatga ggaacagaga aagccaaaag gtttgtttac tcaaactagc aactcttttc
    43981 caatcatcct ctccaactgc tcgggccaac agcatgaccg ttgccgtagc gacgccaaag
    44041 gcaggcatat agttaaactg ggtcaagact tctccgattg cattcccagc aactgcctcc
    44101 gtcccaaaag aaacgaccaa ggcaatgatc actacatctc cagccctcat cataagtcgc
    44161 tctccagctg ctggtaaagc caaggtcaac agttccttat ctaaaccaaa agttggcttc
    44221 ccataaggca gttttaattg tgaccacaaa atcacaagac caaccaaacg agacacaatt
    44281 gtcccccaag caacaccagc tatccccata tccagaacaa aaatagctag acttgaaaaa
    44341 agaatattca aggcattgga taaaaaacta acatagagag gcagacgtgg attatgcgtt
    44401 gcacgaatca aggctcctag actagtcatt aaacctaaga gaacaatcga tccgcctacc
    44461 aaagatagat acagtccacc actctcagct acatccctct ccgtccccaa aagtcctatc
    44521 atctctttcc cagcgaagat ggacaaaaat cctaaaagga aacttaatag taaggtaatc
    44581 ttcaacgcct cagtcacatg ataggccaac ttcgactggt ctttctgccc tatgcttttt
    44641 gaaataacac tggaaatagc agctcccaga gcgatgaaaa tcgcctgata aatggtgata
    44701 atattaccag ctactgaaac ccctgaaata gctatcaatc ctaaatgagc aaccaaataa
    44761 ctgtccacca ttcccattag catctgcaaa aagttttcac ccatagctgg caatgcaata
    44821 ttaagaatgt ctttattttt cttaaacaat ctctcctcct gatgaaaaga aactcagttg
    44881 gtttcccaac cgagtttgct ccctctgtct taaagtccta aataagcctc aaccgctgct
    44941 tgcatgtcag cagctgccac tgttgtcttg tgacgaattg gagctatttc aagcccatca
    45001 actgctggtg gcactgcaac gcctgagatt tcatgtaatt gagccaaggc ttcaaagtct
    45061 gttaaacctg cttttccagt tacagcttct actgcaacta ctgggaactt gtatggacta
    45121 gctgttgaag caatcactgt cttagttaca tctccagtgg ccgattggta ttttttataa
    45181 actgctgaag caacagctgt atgagggtcc tcgatataag aatctaactc acaaacacgc
    45241 ttgatctctg ctgccgtttc ttcctcagtc gcatattcag ctgcaaagag gtccaaaatc
    45301 tctgcatcaa agtctgtcaa cttatattgt ccttgcgtgt tcaaggcatt cataagttca
    45361 gttgtctttt cagcattatt tcccaaaaga tggaaaatca agcgctccaa gtttgaagat
    45421 accaagatat ccatagatgg gctggttgtt accttaaact cacgtttttt gtcatagaca
    45481 cgtgttttaa agaagtctgt caaaacattg ttgtcatttg aagcacagat taatttacca
    45541 actgggagac cgatttgttt ggcataaaag gcagccaaga tatttccaaa gtttcctgtt
    45601 ggtactgtga agttaatctt atcaccagcc acgatctcac cagtcttgac caactgagca
    45661 taggcataaa cataataaac aatctgtggc accaaacgac cgatattcat agagttagca
    45721 gatgaaaatt gcaacttgtt ggccgctaat ctttcacgaa gagccacgtc gttaaacatg
    45781 tgcttcacgt tggtttgtgc atcgtcaaag ttaccatcta tagcgataac atgagtattg
    45841 tcaccattct gagtggtcat ttgcaactct tgtaccttgc tgacaccacc ctttggataa
    45901 aagacgataa tctcagtacc aggcacatcc gcaaaccccg ccatagcagc tttccccgtg
    45961 tcaccagatg tcgctgtcaa gataacaatc ttgttctcca aaccatgttt cttagcagca
    46021 gtcgtcataa agtatggcaa aatagacaag gccatatcct taaaggcaat cgttgaacca
    46081 tggaaaagtt ccaaattgta ttgcccatct aatttcacta atggtgcaat agctggagta
    46141 tcaaatttgc tatcgtaggc attgttgata cagtagtcca actcctcagc tgtaaagtca
    46201 tctaaaaatg ctgacaaaac tagcttagca acttcctggt aagaagcatc tttcaatttg
    46261 tcaaagttca aatctacctt tggataagta accggtgtaa acaaaccgcc gtccgtcgcc
    46321 aaaccttgca aaattgcttg gctggcagtt actgtattgt tggcatcacg cgttgattga
    46381 taaactaatg tcattactct ctatccttta tctatagtct cgtccattat atcatgattt
    46441 ttcagaaaat tctcccttta taagagaaat tataggctca attcttctct caaaggctgt
    46501 aaataggtca tttcttcctt atttctcacc actagtccct cctcagctag taggagtaag
    46561 tctttggaaa attcaataat cgtagtttct tcctcatctg taagattttt cttagaaaat
    46621 tgtctcctta aagacttgta atcataacca aatactttaa agaaaggtgc tgtttctaag
    46681 taagcttcta acttgtctaa attaaccaat aatcccaagt gaaaagctgc agaagcaaaa
    46741 gtcctatcaa gtggctgtgt acacacacta cgaaactcaa ctgttcctcg agtcgttaag
    46801 tcttggtact ggtaactacg atgagtttca aaatccttct cttgggggga aataataacc
    46861 tcatccccat tcagagcaaa tgcttggatt tcaggcgtag ccaaatagtc cccagcctga
    46921 ataggataaa aataataggt ctgcccatca cgttccgcag taaaaatcgc agaatgattt
    46981 agatagtcaa aaaaatcagc ttcatcatta aggagtctag cattgacccc aacattctct
    47041 ggatagatac catgcataga ttcttcccag aaaatatccc ttgaaatttt cgtatcccaa
    47101 tccgcacccg aaaactcaga gtttgcaaat aaataagcct tagccgcttc aatttgagta
    47161 aaagcattaa tcacccgtaa gtagttggtt tttgaaatat ccagctgaac ctggctccca
    47221 cagataaaag taccatattc agggaaatga tgtaaatctg atttaataat atttctactc
    47281 aaattcaaat aatccatcaa catctgatag cgtggataag ccactggaca attctcattt
    47341 ttatcccagt tgggatggat accacagcca acaatagcat gatttgattc agctaacttc
    47401 ttctggattg cttccatata aatactaaaa cgttcttcaa cttcttgtat cgtttcagcc
    47461 ttaccaaatg caaactcaat cgttgtatag gaaacttcaa ataaaatagc atcctgactt
    47521 atcggatcta ctaactggat caaattgcca aaatcatcta cctttgctac ggtgagatcc
    47581 aaagtagaaa ctaaataatg aaatagatcc tttataactt caacatctgt agcatcccct
    47641 tctaaacttg caacaggata ctccaactca attccgacaa acaattcagg attttcttta
    47701 atatttttca aataccgatg ttttaataaa tcgatagaac aagacatact accctacact
    47761 ttcttaatct aaataaaatt tgaataacta taattatacc aaaaataata taaaaaagga
    47821 acgaagaata acaacgttcc taacactata ctataccggc ggccggggtc gaaccggcac
    47881 gtccttgcgg acactggatt ttgagtccag cgcgtctgcc aattccgcca cgccggcaaa
    47941 tagtaactgg ggtagctgga ttcgaaccaa cgcatgaggg agtcaaagtc ccttgcctta
    48001 ccgcttggct ataccccaat ataaaatagg cgagtgatgg ggatcgaacc cacgcatgcc
    48061 agagccacaa tctggtgtgt taaccacttc accacacccg ccataattct attaacacgg
    48121 gcagtaggaa ttgaacccac actgaaggtt ttggagacct tagttctacc tttaaactat
    48181 gcccgtaaaa tggaagggga gggattcgaa cccccgaacc cgaaggagcg gatttacagt
    48241 ccgccgcgtt tagcctcttc gctacccttc caaaatatat aaatggcgcg agacggaatc
    48301 gaaccgccga cacatggagc ttcaatccat tgctctacca actgagctac cgagccttat
    48361 tgcgggagca ggatttgaac ctacgacctt cgggttatga gcccgacgag ctaccgagct
    48421 gctccatccc gcgttaataa tataaaagga ggatgtggga ttcgaaccca cgcacgcttt
    48481 tacacgcctg acggttttca agaccgttcc c
//
LOCUS       DBEJZV010000017        45412 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.17, whole genome shotgun sequence.
ACCESSION   DBEJZV010000017 DBEJZV010000000
VERSION     DBEJZV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.17"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(89..2086)
                     /gene="metG"
                     /locus_tag="ACL3S0_001143"
     CDS             complement(89..2086)
                     /gene="metG"
                     /locus_tag="ACL3S0_001143"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGR1312057.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQVYVDRMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEVSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2210..3469)
                     /locus_tag="ACL3S0_001144"
     CDS             complement(2210..3469)
                     /locus_tag="ACL3S0_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312058.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3471..4172)
                     /locus_tag="ACL3S0_001145"
     CDS             complement(3471..4172)
                     /locus_tag="ACL3S0_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312059.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4156..5355)
                     /locus_tag="ACL3S0_001146"
     CDS             complement(4156..5355)
                     /locus_tag="ACL3S0_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGR1312060.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5641..6987
                     /gene="gor"
                     /locus_tag="ACL3S0_001147"
     CDS             5641..6987
                     /gene="gor"
                     /locus_tag="ACL3S0_001147"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGR1312061.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGVKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQVAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFTSMYSACTCNRQETRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            7184..7720
                     /locus_tag="ACL3S0_001148"
     CDS             7184..7720
                     /locus_tag="ACL3S0_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGR1312062.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGTGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7781..7927
                     /locus_tag="ACL3S0_001149"
     CDS             7781..7927
                     /locus_tag="ACL3S0_001149"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312063.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKAKLMRFEEI
                     FEEY"
     gene            complement(7924..8139)
                     /locus_tag="ACL3S0_001150"
     CDS             complement(7924..8139)
                     /locus_tag="ACL3S0_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGR1312064.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8237..8557
                     /locus_tag="ACL3S0_001151"
     CDS             8237..8557
                     /locus_tag="ACL3S0_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312065.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8587..8925)
                     /locus_tag="ACL3S0_001152"
     CDS             complement(8587..8925)
                     /locus_tag="ACL3S0_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGR1312066.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8937..9656)
                     /gene="trmD"
                     /locus_tag="ACL3S0_001153"
     CDS             complement(8937..9656)
                     /gene="trmD"
                     /locus_tag="ACL3S0_001153"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGR1312067.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9646..10164)
                     /gene="rimM"
                     /locus_tag="ACL3S0_001154"
     CDS             complement(9646..10164)
                     /gene="rimM"
                     /locus_tag="ACL3S0_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGR1312068.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10195..10983)
                     /locus_tag="ACL3S0_001155"
                     /pseudo
     CDS             complement(10195..10983)
                     /locus_tag="ACL3S0_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(11087..11372)
                     /locus_tag="ACL3S0_001156"
                     /pseudo
     CDS             complement(11087..11372)
                     /locus_tag="ACL3S0_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
     gene            complement(11560..11799)
                     /gene="kphA"
                     /locus_tag="ACL3S0_001157"
     CDS             complement(11560..11799)
                     /gene="kphA"
                     /locus_tag="ACL3S0_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGR1312069.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(11819..12091)
                     /gene="rpsP"
                     /locus_tag="ACL3S0_001158"
     CDS             complement(11819..12091)
                     /gene="rpsP"
                     /locus_tag="ACL3S0_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGR1312070.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            12270..12470
                     /locus_tag="ACL3S0_001159"
     CDS             12270..12470
                     /locus_tag="ACL3S0_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312071.1"
                     /translation="MNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDLLAD
                     DSLAGDIILLWRIQFGTFTTET"
     gene            12949..13161
                     /locus_tag="ACL3S0_001160"
     CDS             12949..13161
                     /locus_tag="ACL3S0_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312072.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            13244..14047
                     /locus_tag="ACL3S0_001161"
     CDS             13244..14047
                     /locus_tag="ACL3S0_001161"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGR1312073.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITINSIEVVKDYDFKS"
     gene            complement(14104..15645)
                     /locus_tag="ACL3S0_001162"
     CDS             complement(14104..15645)
                     /locus_tag="ACL3S0_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR1312074.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(15647..16129)
                     /locus_tag="ACL3S0_001163"
     CDS             complement(15647..16129)
                     /locus_tag="ACL3S0_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR1312075.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(16170..17213)
                     /gene="rlmN"
                     /locus_tag="ACL3S0_001164"
     CDS             complement(16170..17213)
                     /gene="rlmN"
                     /locus_tag="ACL3S0_001164"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGR1312076.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVRMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHIMVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGATVWFVKSMVQ
                     ILTQLVDNCALTQ"
     gene            complement(17234..17764)
                     /locus_tag="ACL3S0_001165"
     CDS             complement(17234..17764)
                     /locus_tag="ACL3S0_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGR1312077.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(17921..18526)
                     /gene="sodA"
                     /locus_tag="ACL3S0_001166"
     CDS             complement(17921..18526)
                     /gene="sodA"
                     /locus_tag="ACL3S0_001166"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGR1312078.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAVA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(18699..19736)
                     /gene="holA"
                     /locus_tag="ACL3S0_001167"
     CDS             complement(18699..19736)
                     /gene="holA"
                     /locus_tag="ACL3S0_001167"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR1312079.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNVIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(19770..20705)
                     /locus_tag="ACL3S0_001168"
     CDS             complement(19770..20705)
                     /locus_tag="ACL3S0_001168"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGR1312080.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(21258..22448)
                     /gene="metK"
                     /locus_tag="ACL3S0_001169"
     CDS             complement(21258..22448)
                     /gene="metK"
                     /locus_tag="ACL3S0_001169"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGR1312081.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(22663..24006)
                     /locus_tag="ACL3S0_001170"
     CDS             complement(22663..24006)
                     /locus_tag="ACL3S0_001170"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR1312082.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(24146..24961)
                     /locus_tag="ACL3S0_001171"
     CDS             complement(24146..24961)
                     /locus_tag="ACL3S0_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR1312083.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWIWAYNHIGYNRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(25013..27193)
                     /locus_tag="ACL3S0_001172"
     CDS             complement(25013..27193)
                     /locus_tag="ACL3S0_001172"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGR1312084.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(27461..28387)
                     /gene="ftsX"
                     /locus_tag="ACL3S0_001173"
     CDS             complement(27461..28387)
                     /gene="ftsX"
                     /locus_tag="ACL3S0_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGR1312085.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(28380..29072)
                     /gene="ftsE"
                     /locus_tag="ACL3S0_001174"
     CDS             complement(28380..29072)
                     /gene="ftsE"
                     /locus_tag="ACL3S0_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGR1312086.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(29090..30185)
                     /gene="prfB"
                     /locus_tag="ACL3S0_001175"
     CDS             complement(join(29090..30112,30114..30185))
                     /gene="prfB"
                     /locus_tag="ACL3S0_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGR1312087.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(30293..30949)
                     /locus_tag="ACL3S0_001176"
     CDS             complement(30293..30949)
                     /locus_tag="ACL3S0_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGR1312088.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(31257..31967)
                     /locus_tag="ACL3S0_001177"
     CDS             complement(31257..31967)
                     /locus_tag="ACL3S0_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312089.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(31967..32731)
                     /locus_tag="ACL3S0_001178"
     CDS             complement(31967..32731)
                     /locus_tag="ACL3S0_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312090.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(32731..33687)
                     /locus_tag="ACL3S0_001179"
     CDS             complement(32731..33687)
                     /locus_tag="ACL3S0_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR1312091.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGTLLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(33691..34560)
                     /locus_tag="ACL3S0_001180"
     CDS             complement(33691..34560)
                     /locus_tag="ACL3S0_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR1312092.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(34828..35988)
                     /locus_tag="ACL3S0_001181"
     CDS             complement(34828..35988)
                     /locus_tag="ACL3S0_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1312093.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(36089..36337)
                     /locus_tag="ACL3S0_001182"
     CDS             complement(36089..36337)
                     /locus_tag="ACL3S0_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGR1312094.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(36416..37006)
                     /gene="clpP"
                     /locus_tag="ACL3S0_001183"
     CDS             complement(36416..37006)
                     /gene="clpP"
                     /locus_tag="ACL3S0_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGR1312095.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(37180..37809)
                     /gene="upp"
                     /locus_tag="ACL3S0_001184"
     CDS             complement(37180..37809)
                     /gene="upp"
                     /locus_tag="ACL3S0_001184"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGR1312096.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(37898..38365)
                     /locus_tag="ACL3S0_001185"
     CDS             complement(37898..38365)
                     /locus_tag="ACL3S0_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGR1312097.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(38384..38941)
                     /locus_tag="ACL3S0_001186"
     CDS             complement(38384..38941)
                     /locus_tag="ACL3S0_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR1312098.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFRETRKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            39066..39911
                     /locus_tag="ACL3S0_001187"
     CDS             39066..39911
                     /locus_tag="ACL3S0_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR1312099.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            39970..41145
                     /locus_tag="ACL3S0_001188"
     CDS             39970..41145
                     /locus_tag="ACL3S0_001188"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR1312100.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            41165..41620
                     /locus_tag="ACL3S0_001189"
     CDS             41165..41620
                     /locus_tag="ACL3S0_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR1312101.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(41649..42389)
                     /locus_tag="ACL3S0_001190"
     CDS             complement(41649..42389)
                     /locus_tag="ACL3S0_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGR1312102.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAVYVQTNAE"
     gene            42494..42715
                     /locus_tag="ACL3S0_001191"
     CDS             42494..42715
                     /locus_tag="ACL3S0_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGR1312103.1"
                     /translation="MIFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGWPSGLVPFGSFPT"
     gene            42634..43968
                     /locus_tag="ACL3S0_001192"
     CDS             42634..43968
                     /locus_tag="ACL3S0_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGR1312104.1"
                     /translation="MGVETWFYSSICWLAIGLGSVWKFPYMTAANGDGGFLLIFLIST
                     ILIGFPLLLAEFALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSIIGG
                     WILVYLGIEFGKLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKG
                     IERASKVMMPLLFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFF
                     ALSLGVTVMLTYASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGG
                     PSLLFIVLPQLFDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVI
                     LGILTFVFGIPSALSYGVMADVHIFGKTFFDAMNFLVSNLLMPFGALYLSLFTGYIFK
                     KALAMEELHLDERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKGLE"
     gene            complement(43990..44934)
                     /gene="manA"
                     /locus_tag="ACL3S0_001193"
     CDS             complement(43990..44934)
                     /gene="manA"
                     /locus_tag="ACL3S0_001193"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGR1312105.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(45055..45375)
                     /locus_tag="ACL3S0_001194"
                     /pseudo
     CDS             complement(45055..45375)
                     /locus_tag="ACL3S0_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
BASE COUNT        13199 a         9905 c         8417 g        13891 t
ORIGIN      
        1 acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaat aaaaaaacag
       61 aactagcctg aactagtcct gtctactttt acccaatcac acttccattt ggtacagctg
      121 gatcaactgt gagaagggtt aatttgccat catgttcagc tgagagaatc ataccctggc
      181 tgacatattt tttcatcatt ttacgtggtt tgaggttagc aacgatttga actttcttgc
      241 cgaccaattc ttgttcattt ggatagtatt ttgcaattcc tgaaagaatc tgacgatctt
      301 ctccatcacc agcatccaag cggaattgaa gcaacttatc tgaaacttct actttagaca
      361 cttctttgac ttctgcgaca cggatttcaa ccttgtcaaa gtcttcaaac ttgatttcat
      421 ccttgtttag tttgagctca acttcgtccg gattccattc tttttcgact gctggtttat
      481 tgccttccat ttgttccttg atataggcga tttcttcttc catatttaga cgtggaaaga
      541 taggtgttcc tttggcaact acagtcacat ctgctgggaa gtcagccaaa ctcaagtttt
      601 caagactaga aacttcttcc aaaccaagtt gagtcaaaac tgcacgacta gtttccatca
      661 taaatggttc aatcaagtga gcaactacac gaatgctggc tgccaagtgg ctcatgacac
      721 ttgccaattg gtcacgaaga gcttcatcct tggccaagac ccatggtgcg gtctcatcga
      781 tgtatttatt ggtacgagag atcagagtcc agactgcttc aagcgcacgt ggatagtcaa
      841 ctgcttccat gtgtgtatgg aagtctgcga ttgattgttc tgcaacctca gcaagaacat
      901 gatcaaattc agtcacacct tctacatagg cagggatttg tccatcaaag tacttattaa
      961 tcatggaaac cgtacggtta aggaggttcc caaggtcatt agccaattca tagttgatac
     1021 ggccgacata gtcttcagga gtaaaggttc cgtctgaacc aactggaagg ttacgcatga
     1081 ggtagtaacg aagtggatct agtccataac gctctaccaa catttcaggg taaacgacat
     1141 tcccttttga cttagacatt tttccgtctt tcatgacaaa ccaaccatgg gcaatcaaac
     1201 gatcaggtaa tttaacatcc aacatcataa gaaggattgg ccagtagata gagtggaagc
     1261 gaaggatatc ttttcctacc atatggaaga ctgttccatt ccagaacttg tcaaagttac
     1321 catgttcgtc ttgagcgtag ccaagagctg tcgcatagtt aagaagggca tcaatccaaa
     1381 cgtagacaac gtgttttgga tttgatggga caggcactcc ccatgtaaag gttgtacgag
     1441 ataccgccaa atcttccaag cctggctcga tgaagttgcg tagcatttca ttaaggcgac
     1501 catctggcgt gataaattca ggatgagctt tgaaaaattc gaccaaacgg tcttggtatt
     1561 tgctaaggcg aaggaagtat gattcttcag aaacccattc aacctcatga cctgatggag
     1621 caataccacc agtcacattt ccagcttcat cacggaaaac ttctgccagc tggctttctg
     1681 taaagaattc ttcgtctgat actgaatacc aaccagagta ttcacccaag tagatatcat
     1741 cttgagcaag taagcgttca aagacctgtg cgacaacttt ttcatggtag tcatcagttg
     1801 tacggataaa tttatcgtat gagatatcta gtaattgcca gagttcttta actccaaccg
     1861 ccattctatc aacatagact tgaggtgtaa taccagcttc ttccgctttc tgctggattt
     1921 tctgaccatg ttcatcaaga cctgtcagat aaaatacatc gtagcccatc aggcgtttgt
     1981 aacgtgctag gacatcacat gcgatagttg tgtaggcaga accgatatga agtttcccag
     2041 atggatagta aatcggcgtt gtaatataaa aattcttttc agacataatt tttcctttcc
     2101 aggcaaatga aacctgtttt tctaacactt cattatatca catttttaat gaatttcgat
     2161 agggaaatcc atacaaaaac aagatagacg agtgtccatc ttgttgatct cattcataac
     2221 gaagggcttc aattggatca agtttcgatg ccttgttggc tggcaagact ccaaaaatca
     2281 taccaacact agccgaaact gcaagactaa atagggcaac tgggattgat actccaactt
     2341 ctataccttc tattaaacct tgcagtaaca aacctgctaa ggcagttaaa ccacttgcaa
     2401 ttgtcaagcc aattaagcca cctaacaagg tcaaaatcat ggattcaatc aaaaactgaa
     2461 ttaaaatatt ggcacgtgtt gcacccaaag ccttacgaag accaatctca cgagtgcgct
     2521 ctgtcaccga aaccagcatg atgttcatga caccagttcc tccaacaaag agagaaatcc
     2581 ctgcgatgga actaataatc gtcgtcataa aactaaacga ttgttgaatt tctgcaaata
     2641 caacggactc atctgccacc tggtattctc cctgttgtaa gcctgcaagc tctgtcattt
     2701 ttcgtgccag ttctggaccc agagttgggg ttaaactggt atcattcact cgaaagacaa
     2761 tactagctat ttcatctata ttaaaattcg cagcaaggga gatattggta gtaataggca
     2821 agccaccaaa cccatatatt tttgaccttt tagcctccgg actagtataa accccaatga
     2881 cccggtaact aaatccattg acttctacaa ccttgttaat agcctcttga ggagattcaa
     2941 ataaactaat ggacaattcc tcatctagca aaataacact tgcaaactct ttgaaatctt
     3001 gctctctcag actacgacct gcaataattt cattcttaac agcatccatg taagttctgt
     3061 ttccacctgt caaattagca ttctcaacct ttttatcttg ataggtcaag atggcattcg
     3121 ttgaattggt tacatagtaa ctatccactc ccttcagttt agctgcctct tgaacccagg
     3181 attcttgcgg ttttggcggt tcaacaggaa cttcctcttc ctttccagaa accgtaaaag
     3241 ctgattgttt ctgagtaaaa gacccatctt tacttttttt aggagagaaa aagacgctaa
     3301 tatttttctg agatttagtc atatctttat tgacttgacg agatagggaa tcacccaaag
     3361 ccataatcac aacaactgat gaaacaccga taataatccc aatcatagta agcaaagaac
     3421 gcatcttgtg agccatgata gatgaaaagg caaatttcag attctgcatc ttagttttcc
     3481 tcctttccta actgagcact gtcagacgaa atgaccccat cccgaatgac aatctgacgt
     3541 ttggcatagg cagcaatctc aggctcatgc gttaccatga taatggtttt tccttcttta
     3601 ttcaaatcaa ccaataattg cataatttgg ttacctgttt tggtatccaa ggctcctgtc
     3661 ggttcatccg ctaggataat agaaggattg tttaccaagg cacgcgcaat ggctacacgt
     3721 tgcttttgac caccagataa ttctgaaggt aaatggtgac tacgttctgt caattcaacc
     3781 ttgtctaaat attcctcagc caacttgcga cgttttgaag acgaaactcc tgcgtaaatc
     3841 aagggcaatt ctacattttg cagagcattg agcttcgata gaagaaagaa ctgctgaaag
     3901 acaaaaccga tttgttggtt acggacctta gccagttgtt tttcaccaag cccagccact
     3961 tcttgacctt caagataata ttctccactg gttggtgtat ccaacatgcc aatcgtattc
     4021 atcagagtgg acttaccaga cccagatggt cccatgatgg ctacaaattc accctcattc
     4081 acttctagat tgatattttt gagaacctgc agttcttggt caccattacg gtagcttctg
     4141 aagatatttt ttagactaat tagttgcttc atcagccttc acctcttttc cttcttccaa
     4201 ggaagatgtt ggattactga tgaccttagc accatttgtc aaaccagaag tgatttcttg
     4261 attttctgcg tcagcatttc ccaatgaaac ctcaactttt ttagcctttt gttgttcatc
     4321 cacaatccag acataatttt tactatcatc cattactaga ctgctaacag gaacaagaat
     4381 agccttagtt ttgcttttaa cctcaatgtt gacagaaaaa ccttgtttca aatcaccaac
     4441 ctcgcctgtc acatcaatag tataagggta tttagaacct gtattattcc cggctgctgg
     4501 actagctgct tcaccattgt ttttaggata gtcagaaata tagcttaatt tcccagtcca
     4561 ttttttatca ggatacactt tagaagtaaa gcttacttct tgacctacag aaaggttggc
     4621 tagattgtac tcagacaatt ctcccttgac ttgtaaattt tcattgctga caatatgaac
     4681 cataacttga ctcgcccctg ttggagattt agaaacattg ctattgactt cgaccacagt
     4741 tccctctagg gtactgagaa cagttgttgc atccaattga ctttgagcct tgcttaattg
     4801 cgctgcagca tctgcacgcg catcacgggc atcacccaat tgagcatcaa tagaagcaac
     4861 agaatttcca gccactggag ttgggctttg caccgttgca tcttctcctc ctactggcgc
     4921 tggtaactgt ggagcctgag ctgaagcggc ttcatttcgt gcttgattga gttcattgat
     4981 atgacgatct gccttagcta ctgctcgact agctgaatca taggccgcct gcgcttctga
     5041 actactgtac ttgactaaag cctgcccttc gctgacctta tcgcccacag aaacaaggat
     5101 ttcatctaaa tcacccttac tagcatcaaa ataaacatat tgttcatttt ttgctgttac
     5161 tgtccctgac aataaaacag aggatgccac gcttccttcc ttggcaacaa caagatgagt
     5221 aggctcatct tttacagcag tctgagaagg ttgtctaaag agtaaaatcc ccccggcacc
     5281 caatacaact acactcgcag caccgattgc tgcatacagt tgccactttt tagctttacc
     5341 attctttttc ttcataatga aactcctttt cttttttaca atactttgct attataccaa
     5401 atttccctcc agcaaacaat gcagttcaga tggaaataat ggcagttcag gattaaacaa
     5461 tcgttcggaa ttttgctttt ctattgtact agatatataa tacactattt tgacttattt
     5521 ggcaagcttt tttgcaattt tttgtgcgta gcagattttt gcaatcaaat caaaaaaaga
     5581 ataaaatata actatcaaaa aagacgctct actatttaaa agattacaaa ggagttttca
     5641 atgagagaat atgatatcat tgctatcggt ggaggtagcg gaggaatcgc taccatgaac
     5701 cgtgctggtg aacatggagt caaagcagcc gttattgagg aaaagaaatt aggtggaacc
     5761 tgtgtcaacg tcggttgtgt tcctaaaaaa atcatgtggt acggggcgca agtcgctgag
     5821 actttccatc aatttggaga agactacggc tttaagacta ctgatcttaa ctttgacttt
     5881 gcaaccctac gtcgcaatcg tgaagcctac attgatcgcg ctcgttcttc ttatgatggt
     5941 agttttaaac gcaacggtgt agacttgatt gaaggtcatg ctgaatttgt agattctcat
     6001 actgtaagcg taaatggtga actgattcgt gctaaacata tcgtgattgc tacaggtgcc
     6061 catccaagta ttcctaatat tcctggtgct gagctaggtg gctcttctga tgatgtattt
     6121 gcctgggaag aacttccaga gtcagttgcc attctaggcg ctggttatat cgccgttgaa
     6181 ttagctggcg tactccacac ttttggtgtc aagacagatc tctttgttcg ccgcgatcgt
     6241 cctttacgtg gttttgattc ctacatcgtt gaaggtttgg tcaaggaaat ggaaagaaca
     6301 aacttaccac ttcacactca caaagtccct gtcaagttag aaaaaactac tgacggcatt
     6361 accattcatt tcgaagatgg tactagtcac acagctagcc aagttatctg ggctacaggt
     6421 cgccgtccaa acgttaaggg cttgcaactt gaaaaagctg gagtgactct gaacgaacgt
     6481 ggctttatac aagtggatga ataccaaaat accgtcgttg agggaatcta tgctctaggt
     6541 gatgtaacag gcgagaaaga actgactcca gttgcaatca aggctgggcg taccctatca
     6601 gaacgtctct ttaacggaaa aacaactgca aaaatggact actcaactat tccaactgtt
     6661 gtcttttcac accctgctat cggaactgtt ggtttgacag aagaacaagc tattaaagaa
     6721 tacggtcaag accaaatcaa ggtttacaaa tcaagcttta cttctatgta ctctgcttgc
     6781 acttgcaacc gtcaagaaac tcgtttcaaa ttgatcacag ctggttcaga agaaaaagtt
     6841 gtcggacttc acggaattgg ctacggcgtt gatgaaatga ttcaaggatt tgctgttgct
     6901 atcaaaatgg gagcaaccaa ggctgacttt gacgcaactg tagcgattca cccaacttca
     6961 tctgaagaat ttgtaaccat gcgttaatcg aaacaaaaga agctgatata aatatgtctg
     7021 cttctttttt aatgattttc gaatcaacaa aaaaattatc caacttgact agtcacgaaa
     7081 atcggctgtt acagtttttg ttaccttgtt tttaaaaaat ggttgacatc gactcctata
     7141 tgagtataat agttaatata cattagaaaa gaggttaact attttgaaaa aagctcacgt
     7201 ttatgctatc cctgctattg gggctgctct cattgctgtt ttggcacaaa tcagtcttcc
     7261 aattggacct gttcccttca ctctgcaaaa ctttgcaatc ggcttgattg ctactgtctt
     7321 tagaccgaga gaggctgtac tttctgctgg actctatctt cttctaggtg ctatcggtct
     7381 tcctgtcttt gcaggaggtg gaactggttt tcaggcttta gttggcccta ctgcaggcta
     7441 tctttggttt tatctcgttt actctggact tacttcctct ctaaccaaca gcaagagtgg
     7501 tgttgttaag atttttcttg caaacctctt gggtgatgcc cttgtctttg tcggcgggat
     7561 tctcagcttg catttcctag ctggaatggc atttgaaaaa gctcttgttg tgggggttct
     7621 tccctttatc attccagacc ttggcaaact tctggctatt agttttatta gccgtcccct
     7681 acttcaacgc cttaaaaatc aggcttactt tactaactaa aaaaggatac cgagttatca
     7741 tgactcaata tccttttttt attttgaaaa cttatactca atgaaaatca aagagcaaac
     7801 taggaagcta gccgcaggct gctcaaaaca ctgttttgag gttgtggatg aaactgacga
     7861 agtcagtaac catacatacg gcaaggcaaa gctgatgcgg tttgaagaga ttttcgaaga
     7921 gtattagttg cctttaaagg catccaccat cgtttgaaat tcttcatttg agagagtaat
     7981 ccctttgccc attttagtat ggtctggact ccaagcacga atatcaaact ttgcaggggc
     8041 accattaaag ctcacacggt taatttcctt ggtccaacct ttttcgtttt cagaaagagt
     8101 caacaagtgc tcttcgattt caaatgtaaa ttctgccatt ttcttctcct tttttagttt
     8161 cattagttta ttcgtaaaat cttgtagatt ttaggaaaat tttatataat attgatataa
     8221 aagaagggag gccaatatga gacataaatt ccagcaagtt ctaaataaaa tacatgattt
     8281 tttaaatgga tatgaccaac ctgaccagac tgaaaccaac tcccttacag ccactattga
     8341 agaggctatc cagaaacaaa ccgctgttca ccttatctta tctgagacaa gctttacagg
     8401 tgacatcatc aaatatgatc agcaaggcca gcaaattatc gtgaaaaatt tttccaaaaa
     8461 tgtgagccgg attatccgta taagcgatat tcaacgcctg cgatttgtcc cctcaactgt
     8521 ccaaacagcc caaaaaaata gatttaagaa agagtgagat gtagttgctt catcccactc
     8581 tttttcttag cgaatttgtt caaaatgtaa atgaactgcg atatgatctc cataaccact
     8641 tctttccaag tcacgttgta aacgatagga aatatagtgt tctgcaatgg taatgtaacc
     8701 tgcgcccaat aaacgatgtt caaccataga ttgaatcata ctgatagtcg cacgttccac
     8761 cttggcttct tgtaaatcca aaactacctt cttagtgact tgagcaagat tttgacgcaa
     8821 atcatctgtc aaaacataaa cagtttgggc tgccttcaag atggcttggt aaatcttatc
     8881 tggattaaat tcagcaattt cgccattacg tttgattact tgcataggtt tctcctttat
     8941 tctttgtttt ctttgatttc tgccagcatt ttttcttctt ctactgtcag ttgataatgt
     9001 tcaagtaaat ctggtctgcg ctcgtaggtt ttctttaaac tctcgtacaa tcgccactga
     9061 cgaatctttt catggtggcc actcatcaat acatctggca cgaccatgcc tcgataatca
     9121 tagggacgtg tgtactgagg atattctaaa agacctgaag aaaaactatc atcttggtgg
     9181 ctagactcct tgccaatcac ttctggaatc aggcgaactg tagcatcaat catggtcata
     9241 gctgccaatt ctccaccagt gaggacatag tcgcctaggg aaatctcatc tgttaccaag
     9301 gtcttaatgc gctcatcata accctcatag tgcccacaga taaagattag ctcttcctct
     9361 tgagccaaat cttcagcata agcctgatca aactgctttc cagcaggatc gaggagaata
     9421 acgcgcggat ttttcttttc aatagcatca aaggaatcga aaataggttg tactctgagc
     9481 aacatgccct gaccgcctcc gtagggctca tcatctacat gacgggcctt ttcagcattt
     9541 tctcgaaaat tatgatactg gatatccaag agcccttttt ctcgagcctt tccaacgatt
     9601 gagtgctcca gtggagaaaa catctctgga aagagggtta aaatatcaat cttcatcgtc
     9661 taacccttct aagatttcca catcgacccg tttatttgga atatcaacat tgagaaccac
     9721 tggtgggata taaggtaaaa gcaaatcacg tttgcctttt cgtttgacca cccagacatc
     9781 attagcacct ggttgcagga tttccttgat ggttccaacc aagctatcac cctcatagac
     9841 ttccaaaccg ataatctcgt gatagtaaaa ttcaccatcg tctaggtcat tcaaatcttc
     9901 ctcagcgacc ttgagactgt atcccttgta cttttcgata gtattgatat ggtacatatc
     9961 tttgaattta ataatgtcaa agttcttctg tttacggtgg ctagcgatgg tcactgtttg
    10021 gacaaactga tctttttcat caaacaaagc cagctcagct ccttttttaa accgttcttc
    10081 tgcaaaatcc gtcacagaca agactcgcat ctcaccctgt aatccctgcg tattaacgat
    10141 tttcccaaca ttaaagtagt tcatcttgtc tcctgtaatc tccttttttc catcttattc
    10201 tgacaattct cgaataatag ccgcaatttt ttccgattct gaccattgta aataatggtg
    10261 attccttcct aaaatgagtt tagtattgga agtccaatat tctgattctc tgtactcttt
    10321 ttctctataa gtctgacaaa aaataaatac agggacatga gattctatcg acaaattctc
    10381 aaaatcttcc tcagtaatct ctccagatat ctgaaattct ggatcttgat tttccaactc
    10441 taagcctttt tcttgcatta attcccagat ttttttattc gtttcaggac taaatgttgc
    10501 ttgagttaag ttcttaaaat aaagttcagg accacactcg tcaatcagcc tcatctactc
    10561 ttccatttct ggataaggat tttctgaaaa atcagcaaac atgacttttt tagttgtcgg
    10621 ttcaattgct actaaagtct gacgcttaat tggtttctcg agtaatttgc aagctaaaat
    10681 tccactccaa ctatgtgcac aaagtatata ttcagaaatt cctaattctt caagtacttc
    10741 ataaaccgca tctgcaagat tatctagttt ttttccagct tggtcatgaa tcggactcct
    10801 acctgtgttc ggaaaatcaa ttgtcaaata accaattgta ggaggaggtt tttcaagtat
    10861 aagtgaaaaa ttttcataac ttggtagcaa acctgctccg tttagacaaa ctagcacttt
    10921 cttttgcttt tgataagtaa cagagaggct accaatttct gtagatactt caaacctctt
    10981 cataaagaaa tccactgatt ctatataatg aattattaaa aatccttatc ctttatttta
    11041 tcacgttcca aggattttct caagttggag gaaggggaca acatctctac tttcccttca
    11101 agaatccttc caaattatgt ttatgttggt aattaacggc tgcggttttg tctttctcaa
    11161 agacagtctt ggtaaggtca atatgattaa tagctacgat tgcgacggtg tagtaaatga
    11221 tatcagccag ttctctggca agttcctcgt tcgaatccta tcccttcttt tcgaccagag
    11281 cgcctattca aaacctcggc tacttctccg acttcctcca ctaacttcat aaagagacct
    11341 tcatcagtcc gagactgctg ttaatgttcg attaagtagt cttggaattg cctaaacgtt
    11401 caatctttta tagtatattg aaactagaat agtacacctt tacttctaaa acattgttag
    11461 aaatcgattt gactgtcctg atcgatttgt cctgttcttg tttcatttta ctatatcttc
    11521 tattccacac aaaaaagcga gacatccgtc ccgcccttct tatttttcgt caataacgat
    11581 tcttactttt ttgtattcag ttgggacaga gtagacaatc gttcttatcg cagaaatagt
    11641 gcgaccctta cgaccgatta cacgacccac atcgctttga tcaagattca aatgatattc
    11701 caaaaattct ggtgtatcct caatcttgat agttaaggca tctggttgtg aaattaaggg
    11761 tttcacaatc gcaataatga gattttcaat cgtatccatc tgtcaaccta ctttaaactt
    11821 attttgaaaa tttagaatcg tggaattttt tcaatacgcc ttcttttgaa aggatgttac
    11881 gtactgtgtc tgaaggttga gctccattag ccaaccatgc aagaacgcgg tcttctttca
    11941 aagttacttg gttttcagca acaagtgggt tgtaagttcc aactgtttcg atgaaacgtc
    12001 cgtcacgtgg tgaacgtgaa tctgctacgt tgatacggta gaaaggtttt ttcttagaac
    12061 ccatacgagt caaacggatt ttaactgcca tttttaaagt ctcatttctt taatttttta
    12121 tttcggtgaa atagctgagc tatttagcac atgttctatt atagcagatt tctggcaggt
    12181 gtcaagaaaa aaacttgaca gactataaat ttcttaaagt atttagaaat ttgttagaat
    12241 aggaaataaa tgtttgaaag ctgctatccg tgaatactat tttagaaaaa ttttataaag
    12301 aacaccaagt caaacccttc atatcgcctg aacgagattt ggatacttgg ctcctaagtc
    12361 ccaagcccgt tcccaagcga aatatggact tattagcaga tgattcacta gcaggagata
    12421 tcattttact atggagaatc cagtttggta cttttaccac tgaaacatga ttttaaaaac
    12481 tcccattcga atatgattca aaattcgctt agaatcaatg ttttcccact ttttcaaaaa
    12541 ataaattttc atctaattta aataactttc aattaagtgt gaattttgct taaaatcatt
    12601 aaaaaacacc ccatggtgtg aaccatgaag tgttgcaaat gctgtgttgt agctagatct
    12661 taacgtttag agaactggct agctttacga gctttcttaa gatctggttt ccaaaatact
    12721 ttgagtacac ttatggtatt gatgccccta aacatctaaa aactctggta gaaaaagggt
    12781 atgctcttgt cgaaacttct tttgactcac ttgaccatct aaatactacc ctgaaaaaga
    12841 atatcctgaa gaagaaggga gttactggac tttctaaaat gaaatcttgc gacctggatc
    12901 aagcccttca tgagcatttt tcagaagaag aattagctgg tcactttcat gtccttctat
    12961 ggactttttt acaatggcat tgctatcaca cccaatacct atctaagcgc ctggttcgta
    13021 aactttattg cagctcttcc tctaaatttc ctaattgttg aaccaattgc ccgttttata
    13081 ctaagttctt ttcagaaacc atttactggg gaagaagttg aagattttca agatgatgac
    13141 gaaatcccaa ctattatcta atccagttct gtaaactact aatatttgaa atccacttcc
    13201 ttttagggta caatggtata aatgaatttt tgagaggatc agaatgaaaa aactagcaac
    13261 ccttctttta ctgtctactg tagccctagc tgggtgtagc agcgtccaac gcagtctgcg
    13321 tggtgatgat tatgttgatt ccagtcttgc tgctgaagaa agttccaaag tagctgccca
    13381 atctgccaag gagttaaacg atgctttaac aaacgaaaac gccaatttcc cacaactatc
    13441 taaggaagtt gctgaagatg aagccgaagt gattctccac acaagccaag gtgatattcg
    13501 cattaaactc ttccctaaac tcgctcctct agcggttgaa aatttcctca ctcacgccaa
    13561 agaaggctac tataacggta ttaccttcca ccgtgtcatc gatggcttta tggtccaaac
    13621 tggagatcca aaaggggacg gtacaggtgg tcagtccatc tggcatgaca aggataagac
    13681 taaagacaaa ggaactggtt tcaagaacga gattactcct tatttgtata acatccgtgg
    13741 tgctcttgct atggctaata ctggtcaacc aaacaccaat ggcagccagt tcttcatcaa
    13801 ccaaaactct acagatacct cttctaaact ccctacaagc aagtatccac agaaaattat
    13861 cgaagcctac aaagaaggtg gaaaccctag tctagatggc aaacacccag tctttggtca
    13921 agtgattgac ggtatggatg ttgtggataa gattgctaaa gccgaaaaag atgaaaaaga
    13981 caagccaact actgctatca caatcaacag catcgaagtg gtgaaagact acgattttaa
    14041 atcttaaaaa ccaaaaaaaa tacagtatcc acattcggta ctgtatttct tttactctca
    14101 ttcttaagtt aaattattaa aatcccatat ttggtctatc caaccttcat aaaagtctgg
    14161 ctcatggcag accataagga tagatcccct gtattctttg agagcgcgtt tgagctcatc
    14221 ctttgcatcc acatccaaat ggttggtcgg ctcgtccagc actaaaacgt tgttttcacg
    14281 attcatcaag agacagaaac gaaccttggc ttgctctccc cctgataata cttgaatctg
    14341 gctttcaata tgtttggttg tcaaaccaca acgggcaagg gctgcacgga cttctgcttg
    14401 attaagggca ggaaaggcat tccagacagc ttcaagagga gtttggcgat taccaccttc
    14461 tacttcctgc tcaaaataac caagttctaa ataatctcca cgctccactt ccccagcgat
    14521 tggcgagata atgcccaaga gactcttcaa gagagttgtt tttccaatac cattagcacc
    14581 aataatcgca accttttgat tgcgttcgaa ggtaagattt aaaggcttag taagaggacg
    14641 gtcgtaacca atttgcaagt tcttggcttg gaagataaag cgccctggtg tacgagctgg
    14701 tttgaaatca aaagatggtt ttggtttctc actttggagt tcgataatat ccatcttatc
    14761 caatttcttt tgacgagaca tagccatatt acgagttgca acacgggctt tattacgagc
    14821 cacaaagtcc ttgaggtctg caatctcttt ctgctggcgt tcgtaggctg cctctagctg
    14881 agatttcttc atagcataaa cttcttggaa ctggtagtag tcaccagagt aacgcgtcag
    14941 ctgttgattt tccacatgat agacaatatt gataacgtca ttgaggaatg gaatatcgtg
    15001 cgaaatgaga acaaaggcat tctcatagtt ttggagatag cgcttgagcc aatcaatatg
    15061 ctcagcatcc aagtagttgg tcggctcgtc caacagcaaa atatcaggct tttcaaggag
    15121 aagttttgcc aaaagcacct tggttctttg cccacctgac aaagaagtta catccgtatc
    15181 catgccaaag tccataacac caagagcacg cgctacttcg tcaatcttag catccaaggt
    15241 atagaaatca cgactctcca gacggtcttg aagttctcct acttcttcca tgagagcatc
    15301 aacatccgcg ccgtcttcag ccattttcat atagaggtca ttgatacgag cttcagcttt
    15361 gaaaagctca tcaaaagccg tacggagaac atcacgcacc gactgtcttt cagcaaggac
    15421 agagtgctga tccaagtaac cagccgtcac atatttggac cactcaacct ttccttcatc
    15481 tggcagcatt ttaccagtca cgatactcat aaaggttgat tttccttcac cattggcacc
    15541 gaccaggccg atatgttctc ccttgaggag acggaaggac acatcttcaa aaattgcacg
    15601 gtcaccaaaa ccgtgactca gatttttaac ttctaaaata ctcattttaa ttccttatct
    15661 tgtttttatg taatcgttta taaaggagcc aagccagata gccacccaaa gtattggtcc
    15721 acaaatcatc aatctcaaag acgcgattga aatcaaagaa aaagtccaag attaattgcg
    15781 tacactcgat tccaagactc acaagaaaac taaaaagaag gacctttttt gttttccgca
    15841 aatttggaaa tagataaagg agttggaaaa tcagaggaaa aaacaagaag acattgagga
    15901 tattttgtaa aaaaatccaa cataattgtc caatgtcact cacttcgccc agtttccaga
    15961 gagaattgaa aggagtcaaa agaaaaacca ggcgtccaag atgctgaata tctggagttc
    16021 ccactcccac ggtagattgt tcttgaggag taaagcaaaa atagacaatg caaatgctat
    16081 agaaaatgac tccccagacc aaaatatgat tataagtctt cttcatcatt aaggatttac
    16141 cgctgcgact gccttctggc ggtcacgttt cattgtgtta aagcgcaatt gtccacaagc
    16201 tgcgtcaata tctgtaccat gctcttgacg aaccacacag ttgccccttt tttcttaagc
    16261 gtatcataga aagccaacac gcgctctttg ggactacggc tatattggtc atgctcacta
    16321 actgggttat aaggaatcaa gtttacataa gacaatttct tgatgttctt gagcaattca
    16381 gccaattcca gggcttgttc tacaccgtcg ttgacttcat taagcatgat atattcaaag
    16441 gttacacgac ggtttgttgt ctcaatgtag tattcaatag cagcaaagag tttttcaatc
    16501 ggaaaggcac ggttaatttt catgatactt gaacgaagtt cattgttggg tgcgtgaaga
    16561 gacacggcaa gattgacctg aaccccttca tcagcaaagt cacgaatttt atgagccaaa
    16621 cctgaggttg aaaccatgat gtgacgagca ccgatagcca ttcctttatc atcattgata
    16681 gtacgaaaga aattcaagac attgttgtaa ttatcaaagg gctcaccgat tcccatgaca
    16741 acgatatggc tgacgcgttc atcctgacca cgctcatcaa agtatttctg aaccagcatg
    16801 atttgcgcta cgatttcacc gttattgagg tcacgctgct tcttaatcaa accagaggca
    16861 cagaaggtac aaccgatatt acagccgacc tgagtggtca cacagacaga taaaccatag
    16921 tgttgacgca tgcgtacagt ctcaattaac ataccgtcag gcaattcaaa gagatatttg
    16981 actgtaccat cagcagactc ttgcacaata cgttgtttca agggattgac cacaaactgg
    17041 tcattgagct tagcaatcaa atccttggaa aggttggtca tttcttcaaa tgactgcaca
    17101 cgtttacggt agagccattc ccagatttga tctgcacgga atttcttttc tccctgctcc
    17161 aatacccatt cctgcatggt ttgatgtgtc aaactatgaa ttgagggttt catttcttct
    17221 ccttattctc tactcacttc tgacgaatga caaaatgacg ttgtcccttg tcctctttct
    17281 gagaatgctg gtctttctga cgacgtctat ttttcttatc tgcattcgac tttcgtttgg
    17341 tttgagtcgg tttctttcct tttctagaag gtgtttcttc ttccgtctta cgcattttct
    17401 tgtcaaatga tgctcgctta ggggcttcat tttctaagac aaaataggca caaccataac
    17461 tacaatactc taaaaggtag tcttgtaaac gactgatttt ttcaagtttt tcttctgttc
    17521 ggtcatcctt gtaaaaacct cgtaggcgaa gctgttcgtt gctccagtcc cccacgatat
    17581 aatcaaactt ggttaagact tctgaaaaac gctgattaaa agtcgtcaca tcaaaggcat
    17641 ccttgatatt ttcaaccaag gaaaaagcta tcccttccgt ttcgacctta tccccgtgta
    17701 aatggaactc cggaccagga aacttgttat agttgtataa ttcaggtgca atttcttttc
    17761 gcatagatat cctttttcca cgattactta atactttatt ctaccataat ttctagcagt
    17821 tagcacgttt ctcataaaaa tgaaaaaagt ctaacgattt tgtcagacca gaatcttata
    17881 acctaaaaaa gagaagaaca attcttccct ccaactatca ttatttagca gctgcgtaca
    17941 attcatctac tttattccag ttgattactg aaaagaaagc tttgatgtag tcaggacgca
    18001 cgttgcggta tttcacgtag taagcatgtt cccaaacgtc caagcccaag attggttttt
    18061 taccttctga gattggtgtg tcttggtttg ctgttgaagt cacttcaagt ttcccttctt
    18121 tgttgacaac caaccatgcc caacctgaac caaaacgagt tgttgctgct gcagtgaagg
    18181 ctgcttggaa ttcttcaaat gaaccaaatg ttgcatcgat tgctactgcc agttctgctg
    18241 aaggagctgt tttctcggga gtcatcaatt cccagaaaag agcgtgattc aagtgtccgc
    18301 caccattgtt gataagtgct tgacggatat cagctgggat agattctaca tcagcaagca
    18361 aggcttcaag gtcttcaccg atttcagggt gtttttctaa agctgcattg gcattgttga
    18421 cataagtttg atggtgtttg tcatggtgca aatgcattgt ttccgcatcg atgtatggtt
    18481 ccaaagcgtc gtatgcatat ggaagttctg gtaagataat agccatctgt aatacctctt
    18541 tttctttcta tatgaaaatg ataacgcaaa cattcacttt tttcaagttt tttgcttata
    18601 gataaggaaa tcactgacat actttctaat aaaataagca aatcagcaag aaacccacga
    18661 caagataatc ctgatgcggg ttgtagtttc aacaaatgtc aattgacctg actagcaatc
    18721 tgtaagagtg ccttttcaaa aaggaaacct ttttcataaa gacctgtctt aatctgatag
    18781 tctgtctcaa tcaaatagga aatagcttgc ttcagaaagc tcaaagaaag tcctctcgaa
    18841 tctcttaatg caaacttgat ttgataagga tttgggttac gtcccagata actacctaag
    18901 ctacttgcaa tctgcgattc tgtttggcca gactccgcca aaatcttcac ctgagtaaaa
    18961 gtccgaaatt gtcccagcat gactgcaatc agtttgattt catcttcccc ttgcaaggtc
    19021 aagtctctca ccaaatcgcg cgcctgatcc atctttttag tcagaataaa ctgagttaaa
    19081 tcaaaaatat tgtcctgcaa ggtcttggga attacgttaa caatatcctc ttcctcgata
    19141 acagaatccg ccttatagga ctgtaaaaag agaagatttt tctggatttc gctaaattga
    19201 aaccccgact tgatgaggag attttcaaaa gaatgattgg taaactgcag accttgtttc
    19261 tgactccact tttggaagta ctggcgcaat tcttgttctt ttacttctac tgcatcgaag
    19321 gccttggcat cacgcttaag taatttgact aaccgtcttt tgctatccag ctttccttct
    19381 gcaaagatta tcaacttggt tgttggagaa ggattgtcaa ggtattcctc aaatgactta
    19441 agctcatcat ctgtcaaaaa gcgtttctta gcagtcgtga tatccataaa ataatctaat
    19501 atcacgattt tctcatccgc aaagaaagga aggctgacca actccagttc cacatccttg
    19561 taaactactt ctttcatatc aaagtaggca aagttgaggt cagcagaatc atacccaatc
    19621 tgtttcaaca tttgactctt catcacttca aactgaccct gatctgtccc tgtaaatagg
    19681 ctcaggctcg gtaaatttga taaagtcaac ttctgacttt cttcaatggc tagcatcgtc
    19741 tctcctttct tcagattttt cgatttaatt tagtcaatat agcgcaattt cccacggaaa
    19801 tcttctaagc tctcgtagcc tttttccacc atgattgctt tcagttcatt ggtaatgcgg
    19861 tcaaaagcac tgacgccttc tttgtgaagg gtcgttccca cctgcaccat acttgctcca
    19921 cagaggatgt gttcaaaggc atctcgacca gtcagaacgc cacctgttcc gataatttgg
    19981 atttgaggat ttaaacgttg ataaaaggcg tgaacattgg ctaaagcagt cggtttgatg
    20041 tattctccac caattccacc aaaaccattc ttaggccgaa taacgacaga ttcgtcttct
    20101 atatagaggc cgtttccgat agagttaacg cagttgacaa acttgagcgg atatttgttg
    20161 aaaatagctg ccgcttggtc aaagtgaaca atatcaaaat aaggtggcaa tttaattcca
    20221 agaggtttgg tgaagtaagc aaacacttct gccaaaatcc ggtctgttgt ctcaaaatca
    20281 taggcaatct gaggtttacc tggaacattt ggacaggaaa gatttagctc agtcagacca
    20341 cgaaaatcac tctcttggac ttttttcaaa atagtatggg tttcctctgg agacatgccg
    20401 accagagata agaagaaagt tcggttcgac tctttttcct gcaaatctaa aagataatcc
    20461 aaataatagt ctaagccatt atttggcaag cccatagagt tgatggaacc aagtggaaca
    20521 tcttggtagc gtggctcagg attcccctga cggaagtcca aggtcgctgt cttagtaaca
    20581 aaggttcctg ccgctgagtt tttgacctct tctaactcct ctatcgtcat acaagccaca
    20641 cctgctgcat tcatcaagca attgtcaaac tcaaaaccag caatttgtgt tttcgttgat
    20701 accatgattc taatcctcca gatttctttt attgctaata ttataccata attttaattc
    20761 taggtttact agattctgtg gttctatcta tttattcgga aaagaaagtc tagtacagaa
    20821 gtcatgctat ggaaacagct agtgtattag aagtttgaac aaggcttggg taacagactt
    20881 ttgaatgaag tccaagcaac aaggagaaat ctcaaccatg agtccattcc atgactctgt
    20941 tgctctagaa aaccttgcaa tagtcaagtg ataacgaata aaactttgga ttgaaatatc
    21001 cccaagatta tctattacga ggagaaatct taacctttat catttttaaa gaaatatagt
    21061 aaaatgaaac aagaacagga gaaatcgatc aggacagtca aattgattgc taacaatgtt
    21121 ttagaagttg aggtgtacta ttctagtttc aatctactat acatgtaaat ctctactttc
    21181 gcaaaatgga ttttcagaac agtatcccag tatagttaaa aactataaaa aagagaggac
    21241 gttcccctct taaaatctta ttttactgct tctttcaaag catctacctt atccaaacgt
    21301 tcccatggaa gatcaatatc tgtacgtccc atgtgaccgt aagccgatgt ttgacggtaa
    21361 attggacgct tgaggtccag catttggata atccctgcag ggcgaaggtc aaagatttga
    21421 cgagccgctt tttcaagttg actttcagct actgttcctg taccgaaagt atcgatacga
    21481 acagaaacag gttgcgcaac accgatagca taggccaact gcacttctgc cttcttagca
    21541 aggtctgctg caacgatatt cttggcaata tagcgagccg cataagaggc tgaacgatcc
    21601 accttagtcg catctttacc agagaaggca ccaccaccat gacgagagta gccaccataa
    21661 gtatctacaa taatcttacg accagtcaaa cctgagtccc cttgaggacc accgattaca
    21721 aaacgacctg tcggattgat aaagaatttt gtcttatcat caagataaga agatggaata
    21781 acttctttga tgaccttgtc aatcacatct tgatggattt gttcattagt ggcctctgga
    21841 tcatgctgag tagaaataac gactgtatct acacgtaccg gacggtcatt ttcatcgtac
    21901 tcaactgtaa cttgtgattt tgcatctgga cggagatagc taatttctcc agacttacga
    21961 agttctgcca gacgacgaac caatttatga ctgagtgcaa ttggcaatgg cataagctct
    22021 tctgtttcat ctactgcaaa tccaaacatg agcccttggt cacctgctcc aatcaagtcc
    22081 agtggatctt gatcagcatt tccacgaacc tccaaggctt cgttaacacc ttgagcgatg
    22141 tcaggagatt gttccaccaa agatgggtgt actcccaccg tctcagcaga aaatccatat
    22201 tctgtattgg tataaccaat ctctgcaatg gtatcacgaa ccacacggtt aatatccaca
    22261 taggcatttg tagaaatttc accaaaaacg tggacagaac cagtatatac agctgtttca
    22321 gcagcaacgt gcgcctctgg atcctttgct aaaatagcat ccaaaatcgc atctgaaatt
    22381 tggtctgcaa tcttatccgg atgcccctca gatacagatt cagacgtgaa taatttacgc
    22441 tctgacataa aaatgtcccc ccttaaaaaa tattgttata gagttacaaa gtactgatag
    22501 gaaaactctt cgtaataaat acctaccatc ttatcgggac tatataactt tatcattata
    22561 ccatttttaa tcgcaatttg cagtctttaa tgtagtgttt cggtttagat agttcgttct
    22621 cataaataaa aaagttggag ctcaatactc caacaatttc tattaaaatg tttggcgttt
    22681 agctttacgc tctgcacgac cgcgagcgcg attttcagca cgcttggttt tacggcgctt
    22741 ttcatcaacc gcccattgaa ttttcttctt ataacccggt ttgacttttt tctttttctt
    22801 tttaaccaaa ccaatcattt cgatatcaag tttatcttgt tttttctcac ggttggcacg
    22861 acgatcacgg tcataggtat cttgaaattc cccgtctttg accatcttag gactaaactt
    22921 gattcccaat ttctccaact cacggatatc cgagtcatca cttggctgat aaagggtaat
    22981 agctgtacct ggtaggccat ttcgtccagt acgaccaaca cgatgaacaa aaaaagataa
    23041 gtcttgcgga atggcatcat tgatgacatg gctgacacct tcaatgtcaa tcccacgcgc
    23101 tgccaaatct gttgcgacaa tatactcaaa atccagattt tgcacctgat tcatgattcg
    23161 cttgcgttca cgaggggcaa tatcgccatg gatttttgca accttcaagc cttgagcagt
    23221 cagatatgaa tgcaattcat cagcacgcgt tttagtgtta acaaaaatca ttgccaaata
    23281 cggctgcatc aactgagtca actggtaaat ttgagcattc ttatcatgtc ccttggtcga
    23341 aatcaaccaa ttatcaatgg tgtcagaaat aaccgttttg gtcttaattt tctccataac
    23401 aggattggat aagtattttt tcaagaatgg ttgcagtttt tgtgggatag tcgctgagaa
    23461 gaccatgaat tgcaagtctt ttggaagact gccagcaatc ttatcaacag tttccaagaa
    23521 tcccatatcc aaggtcatat ctgcttcatc aacaacaaat gtcttggctt tatgaatagc
    23581 taaatcacca gatttaacca agtcgtagat acggcctggt gttccaataa caatatgagg
    23641 ctgattgctt gccaatttct caatctggcg agccttatcc gtaccaccca cataattaac
    23701 cacacgaact tcgacatctg agtgagctga aatctgacgc gctacttggt aaatttgagt
    23761 agccaactca cgactcggtg cagtaatcac tgcttgtaca ctatcgctag cttcatctaa
    23821 ttgctggaaa atcggtaaca agaaagtatg agtcttacct gaacctgttt ttgattctcc
    23881 tactaggtca cgacctgcca aaacaatagg aatcaacttg tcttgcacct ctgttggagt
    23941 tgtaaatttt aactcctcca aggcttctct aatatagttt ttaaattgaa atttcgtaaa
    24001 tgacataaca tcctcgattc tatctatctt atcaattata ccatatttta ttccattaca
    24061 gtagtctcac ttatttaggc tatttccagt agcttctcta gtaagaaaag gctggaattt
    24121 tatagttcca acctcttttc agttattatt tccagtttaa catagcattc aagccatagt
    24181 gatcactcac ttgtggactc ttgttaccat caaatacgac atgtaaattt tccaccgcta
    24241 actctttggt agtaaagaca taatcgattc gaaggggttc agtgttccct ttccagccat
    24301 caatttcagg cggaacagta tagctaccac ttttctcttg agcaacttca aatgcgtctt
    24361 gtaagcctaa tggactagct aaaatagctt ggtaaccttc ctgtccagcc ggattgttga
    24421 aatctccagc tagtaaaagt ggcttgttca attttttcaa gacagcctca aatcgtgccc
    24481 attcttcttg gaaaccttta tcccaccaag agagatgaac actggcaact gctagctcct
    24541 tgccatcgac tacagtttca gctagggcaa cacggcgagt atgatagtct gttggatcat
    24601 ccacatctga aaccaaaatt tctctggctt caataggtgt tttagacaag atagccacac
    24661 cttcgtggta gcggttatag ccgatatggt tataggccca gatccagtag taatttttcc
    24721 cttgctcaga caacttttca accaagagtc taacataatg gtcttggtga ataggctcag
    24781 ctgctggcaa agcttgataa aggtcattaa cctccacctc tgacgaggtc atctcctgat
    24841 tgatttcttg aaaacaaatc aaatcatagt ccttttcaag aatatcttca agcaaaatct
    24901 ggaatttttc ctctgcttct ttctccatcc aactgtgagt attgagtgtt aaaaatttca
    24961 ttcttttctc ccaaaataag aggttggaat acagcttcca acctcaagta tattacaatt
    25021 ctactttagc aactgctgtt ttagctgcaa gagaacctgt tttttctaac ttaactgatt
    25081 taattgcatc accatttgtg aagacaacta ctgttgaagt ttcacgtcct gctgcacgga
    25141 tagcatccaa gtcagctgtg acaaggagat ctcctgctgc aactttttgt ccttcagcaa
    25201 catgaactgt aaatggttta ccttcaagac ttactgtgtc caaaccaatg tgaaccaata
    25261 cttcaagacc tgcttccgtc acaataccaa aagcatgttt tgttgggaag atgcttgaca
    25321 cagtacctga aactggagat acaatgtttc catttgcagg ttctactgca aatccatcac
    25381 ccatcatttt ttgagcaaat actggatcct ttacttgttc caaaccaaca acttgaccgt
    25441 ctgctactga ataaacttcc tcagtaagat ctttgaagtg aacagtgttt tgttgtgctt
    25501 cagtcatttg gcttggaaga gtttcaggaa tgatttcacc tgaatcaagg atatcttgga
    25561 tatcagattt caatatgtca gcttttggac cgtagatagc ttgaacccct tgtcctttca
    25621 tgacaagacc catagctcct tctgctttcc attgctctgc atttcctact ttatctgcat
    25681 ctttaacagt tacacgaaga cgagtcatac atgcatcaac atcaacgatg tttacacgtc
    25741 caccaagaag gttgataatg tttacagctt gagagcctgc tgcaactttc acttcgctgc
    25801 tggtttcttc tgaaccttca gcagtttcgt agtttccgtt gcgccctgga gttgcgtagt
    25861 tgaatttttg aatcatgaag tttgcgataa agtacatgat tacagcaaag agaacagtta
    25921 cccaaacgaa gttaacgata tccataccaa taccagcact gattgcaata ggtgtacgag
    25981 tcaagaactc gattgaaccg aatgagtgca tacgtaggtt tacgacgtca gccatagcga
    26041 aggcagcacc ttgaacaagt gagtaaacaa gatacatagg tgttgcgatg aacatgaaca
    26101 tgtattcgat tggttcagta acccctgtca agaatgttgc aagagctgtt gcaatcatca
    26161 tacctttgta tttatgtttc ttgtcagcat caacattacg gtagatagca acaatcacac
    26221 ccatcaagat accgaatgaa ccgatcattt gtccaacttt gaaacgagct ggatgtactg
    26281 tatctaacaa gtgttgatat tgactagcat cagtaccttt aaggtttaca aggtctgtta
    26341 cccatgcaag ccatagtggg tcttgaccga atacttgagt acctttagct gcaccagtta
    26401 aaatgtcata agtaccacca agagctgtgt agttcattgg gatagtcaac atgtggtgaa
    26461 gaccaaatgg caagagcaaa cgttccaaag taccatacaa gaatggtgca agaattggag
    26521 cagtttcttg tgagttggca atccagatac cgaagttatt gatacctgtt tgaactactg
    26581 gccagaaagc agcaagtaga attgcagcga ttgctgaacg aagaataact acaaatggta
    26641 cgaaacgttt cccgttgaag aatgaaagtg catcaggaag tttacggaag ttgtagtatt
    26701 tgttgtaagc agttgcccct acaaaacctg agataatccc tacgaatacc cccatgttca
    26761 aggctggagc ttcaagaaca ctgataaagt aatcagcaac tttgattgaa ccaccaaaga
    26821 aagtagttac catagcatct ggatttttca acatatcgcc tgatacacca aagattgtac
    26881 cagtgatacg gttaatcaag atgaaggcaa gaccagcggc gaaagcacca ccagcacgtt
    26941 ctttagccca gcttcctcca atggctaggg caaacaaaat gtgaaggtta ccgataaccc
    27001 cccaaccgat ttgctcaaga attccacctg tgatgacaag tggtgcaaag gttgggttaa
    27061 tcatcacgat agacttaccg attgaaatca tcaaaccagc agccggcata accgcgataa
    27121 ctaccatcaa agccttaccg aatttttgcc aaaattcgaa agacaagaca tttttgaatg
    27181 tatctttcat cattcaaatc tcctttattt ttatttaggc aaacgtttta cgaaaacgtt
    27241 tgcactttct atgatttaat tataccactt taattttttt tgtaaaggct tttataaaaa
    27301 aattacactt ttttctaaaa aatttctagt gcgccaaatt tcaagttcaa attagccatc
    27361 aagaagtctt ctctggggga cttctttgga atctcttttc aaaaactctt gtagcaaaaa
    27421 aggagatttt acaatctcct cataaaagca gctattttac ctaaatcttc aagaatcggc
    27481 gcatggatat tcctgatccc aatgaaccaa tgaaaacccc aatcacaaat agtagggcaa
    27541 tcatcaacgg actaaataaa tctggactaa tcatggatag attttgccct accaacgatt
    27601 tgttgacaga ttggtaaaca atttgataaa caataaagac caaaacagat ggtgcgatag
    27661 ctcccaataa accgataaag gctccttcta acaagaacgg tccacggata taactgtttt
    27721 tagctccgac caagcgcatg atttgaattt cgcgactgcg ggaaataatg gtaatacgaa
    27781 tggtatttga aatcaagaaa actgcgataa aaattaacaa agcagcaatc cctagtcccc
    27841 aaacacggat aaatgaagct aacttgaaga gtctttctgt attggcaccg ccatcttgaa
    27901 cctcagagac accttcaatt tttttagcat cttcggctat agtttttaca tcatttggag
    27961 tgtttgcctc tacaatataa gcatcataga gaggattggc atctccttca aagattttcc
    28021 agttatctcc cattatctcg gttaattttt catattgttc ttctttactt gaaaaggtaa
    28081 cacttttaac cgtagacatg ttcttcaaag aatcatatac cttgtggtag tcattatttg
    28141 taacagtttg accttctttt tcaattgtct gactattatc ttccacatcc tttcggatat
    28201 aaactactac acggacatta ttttcaatat ctgtagctag tttcgctgta ttgaaaataa
    28261 cagatgcaaa tattgccacc aaggtcaaag taatcatgac tgaactgaca gcagctactg
    28321 tcatccaacc atttcgtttc aaacttttta aggcttcaaa taaatggcga aaaaatctac
    28381 taatcatcgt atccatactc tccttttgat tcgtcacgaa cgacacggcc attttcaatg
    28441 gcaatgacac ggtggcgcaa ggtatttaca atctggctat tatgagtcgc catcaaaata
    28501 gttgttcctt gtaggttaat ccgttccaag agattcataa tttcccatga attatccgga
    28561 tccagatttc ctgttggctc atcagctatc aatactttgg gattatttac aattgcacgc
    28621 gcaatcgcaa tccgctgctg ctccccacct gagagttcat ttggaaaaga acgaacctta
    28681 tgcttcaatc caaccaagtc caaaacttcc atcactcgtc ttttgatatt acggcgattt
    28741 tccccgatta cttccatagc gtaagcaata ttttcataga cagttttctt tggtaacaat
    28801 ttataatcct gaaagacaac cccaacacta cgacgtagaa gcgggacatc tttctttttg
    28861 atcttaacca gattaaaacc agcaactgat aggcttcctt tatcgatttt tacttcacga
    28921 tacagagaac gaataaaagt tgacttccct gctcctgaag gtcctacgat gtaagcaaat
    28981 tcccccggtt gaacgctgac cgaaacaccg cgtagagcag tcgttccgtt gtcgtatttt
    29041 ttaacgacat ctctcatttc aataattgac atgtgagttc ctttctatct tagctaattc
    29101 gccacttgag ataagcatcg ataaaaccat ctaggtcccc atccataacc ttatctacct
    29161 gagcaacctc aaagctagtt cggtgatctt ttaccatagt ataaggcgtg aagacataag
    29221 aacggatttg acttccccaa gtaatctcct ttttctcacc tttgagagaa tctacctccg
    29281 cagccttctt ctcttgctcc atttgataga gcttagcctg caacatcttc atggcacgat
    29341 ctctatttcc atactgggta cgatccactg ttgattggac aacaattcca gttggaatgt
    29401 gggttaaacg tacacctgtt gaaaccttat tgacgttttg tccaccggca ccacctgaac
    29461 ggaaggtatc catcttgata tcatcttcac ggatttccac ttcaatagta tcatccaatt
    29521 ctggcatcac ttctacagat gtgaaagagg tatggcgacg tttggcagag tcaaatggtg
    29581 agattcgcac taagcggtga acacccattt ctgacttgag gagaccatag gcattaggcc
    29641 cttcaaatga taaagttacc gacttaatac cagcctcatc acctgcttgg taatccaaca
    29701 cttccacttt aaagccttta gcattaccat aacgagtata catacgaagc aacatatcac
    29761 cccagtcctg cgcctcagta ccaccagaac ctggatggat ttccaagatg gcattgttgt
    29821 ggtcataagg ttctgacaag agtagagtca tctcgtagct ggtcattatc ttatcaagtt
    29881 cggctaactg cgctaccagt tcatcatgca ctgactcgtc ttcagccaaa aaatccaata
    29941 aaatttcgac ttcatcctgc aactcttcca tcttatggaa ggtattgtaa gtgtttttta
    30001 attcattcaa ttcttgcgac gttttttggg ccgcaatatt atcgttccaa aaatcaggtt
    30061 ctgtcatctt gttttccaag atggcaatct cttcctctag cccttcgagg tcaaagagac
    30121 cccctgaaag aagctaattt ttcacgattt gcgtcaattt tctgacgaat tactgaaatg
    30181 tccataaata ctcctttttt acattatttc attatagcat attttatcat ttctttccat
    30241 cttttgctct aatccccttt tcatgaaaaa agaagccttt gggcttccct tcttacaaga
    30301 cttttgctga agtgcgagcg atttcttcca cttgaatacc atttgcttca aatttttctt
    30361 tcaaggctgg taaatcaatt gatccatcga tttgcacttc gataatgacc ttaccatcct
    30421 tacgcggaat attgactgta tgggatatat tcaaattttc ttctacaatc aaagaaataa
    30481 tttttccaag aacaccaact tcatcttctg taacaaagcg tacacgaatc ccttcttcgc
    30541 cataacctgc aatttcaaga aaggcttgga aaacgtcacg gtcagtaata actccgtata
    30601 cttgatggtt atctacgaca gggagaatac caatcttatt tttcaacatc agataagttg
    30661 catcttctag actagcatag cctgagacag tgacaacatc gcgaatcatg acatctttta
    30721 cttttgtctt attcagaaga taattcatct catagataga aagacttgtt gctttagatg
    30781 gacttgcttg tgcaatggtt ccctcagtca ccaaaccaac caattgatca ttttcgataa
    30841 caggcagacg gtgcaaacct tgctctctca tcaaatctgc tgcatgagat actgttgtat
    30901 ctggactaat ataaactacc ttgcgggtca taaaatcttt aactgccatg agacttctcc
    30961 ttttctattc ttatccccat tatacaatct ttttgtaaat ctatcaaacg cttacatttc
    31021 tttttcgaaa ttcaaaaaag tatgaataag ctagcaaaaa gagctctaaa atcgagctcc
    31081 ctgaatgaag gtaagatacg tttcattcga ttttttcaat tattagaaat taagctttca
    31141 atgtagatgc agatttgttt gcaatctcaa tctaccggct aaaaaggtcc cccggactat
    31201 attgatgatt acttcgtaat cttcatctgc cgactaaaac aatccactgg attgttttag
    31261 ccacctagat atgcttttct gacttcttct gatgaagcga gttcttttcc tgtccctgat
    31321 aggacgattt ttcctgtttc caatacatat cctcggtcag agattgcgag tgctttattg
    31381 gcattttgtt caatcaagag gacggttgtt ccttgcttct gaatatcttg aatgatatca
    31441 aaaatctctt ggatgaagat tggggcaagt cccattgatg gttcatctaa aagaagaagt
    31501 tttggtgttg acataagagc gcgtcccatg gcaagcattt gttgttcccc tcctgaaaga
    31561 gtagctgcat cttggttctt ccgttcttca agacgaggaa agcgtgagaa aaccttcttc
    31621 aagttagctt gattttcttc acgatttttc tttaagaaag ctcccatttc aagattttcc
    31681 ataacagtca agccaggaaa gacgtggcgt ccttctggaa cttgtgaaag accacctgcc
    31741 acgattttct gagctggcat tttttggatt tcttgaccta aaaattcaat ctttcctgaa
    31801 cttggtcgaa ccaaacctga caaggtgcga agaatagttg tcttacctgc accgttggca
    31861 ccgataaggg aaacaacttc tccttcatta acttcaaagc ttacatcacg aactgcttgg
    31921 atcataccgt aatgcacaga aagattttca acttttaaca tagacattag gcttcacctc
    31981 ctagataagc ttcgataacg cgtttattgg tcttaatttc gtctggagtt ccttgagcga
    32041 ttaaacggcc atattcaagt acgtagatac gttctgttac ttccatgacc agattcatat
    32101 cgtgttcaat caacatgatt gtaatcttaa actcatcttt gatacgacga attaactcag
    32161 tcaattcggc tgtttcctgt gggttcatac ctgctgctgg ttcatctaag aagagaattt
    32221 taggttccgt agcaagggca cgaacaattt ccaaacgacg ttgttgtccg taggaaagat
    32281 ttttagcaag agtctctgca tcaccatcta aatcaaagat tttcaacaat tccaaagctt
    32341 tagcctttaa ttctttttca ctcttgtaaa aagctggtaa gcgtaagaaa ctagtaaaaa
    32401 catgctgttt gtgatggttt ccaaaagcaa tcaaaacatt atctaaaact gttaaatctt
    32461 taaagagacg gatattttgg aaagtacgtc caagtcccaa agaggcaatc ttataaggtg
    32521 atttcccatt caaaaggtga ccatctaggg ttactgttcc ctcgcttggt tcataaacac
    32581 cggtcaaaag gttgaaaagg gtggttttcc cagctccgtt tggaccgatt aatccaacca
    32641 gttccccttc gttcaattca agagtcacat ctccaacagc tgttagacca ccaaaatgtt
    32701 tggttaactg ttttacttca agtaatgcca ttagttttgt tcctccttct tagatttttt
    32761 aaagaaacgt gataggctca gttcccatgt tccaaggagt ccacctggtc tgaaaatcat
    32821 taccaatacc aaggccaaag cgtaaataat catacgcaca ctagcaacat cttggagaag
    32881 catattcaaa attcccagaa caatagccga aacaatcgca cctgtaatgg aaccgagtcc
    32941 accaaataca acaataatca aaacgttgat tgagttgatg aaggtgtaat ctttcggtac
    33001 aacagacccg ataaatcctg cctgaagtga cccagcaata cttgcagtaa tggcaccaaa
    33061 gacaaaagcg atgattttaa ttttagtcgt attaacccca actgactcag cagcgatttc
    33121 atcttcacga acagagaggg ttgagcgacc aattgggcta cgcaagaagt tcaaggttgc
    33181 aatggttgta atcacgacaa agaagtaaac catttgccaa gttgtaaagt taggaatccc
    33241 taagatacct gccgcaccat ttgtaaggct tccaccattg atgataaaga tacggataat
    33301 ttcagaaaca cccagagttg ctaccgcaag atagtccccc ttcaagcgca aggttggaat
    33361 gccgacaagt aaggcaactg ctcctgaaag caaagtccct acaagcatag ctccaaagaa
    33421 ggcaccgtag gttggtgatt tagaaccaat aatagctgct gcataggcac caatcgccat
    33481 gaaaccagca tgaccaagtg aaaattgtcc tgaaaaacca acgattaagt tgagaccaac
    33541 agccaaaata atattaattc caatttgttg taaaatctgt acatagaata gattaagtac
    33601 tccgactgaa accagtacac taatcaagct atagccagct aacaaaagga gtaaccatag
    33661 aatattaact tttaaatttt ccttcatcgt ttacaccttc tctttcacat tcttaccaag
    33721 gataccagct gggcggacaa tcaagatcaa caacaagatt ccataaacaa tggcatcacg
    33781 gaaatctgac atcccaaagg ctgtcgcaaa ggtttccaat agaccaatca caaagccacc
    33841 aagagccgca ccaggaataa ttccgatacc accaagtact gcggcaacga aagatttaag
    33901 acctggagta acccccatca aaggctcaag agagttataa taaagagcaa tcagaacacc
    33961 agccgcaccc gcaagagcag aacccaaagc gaaggtaaag ctaatcgtac ggtttacatt
    34021 gatccccatc aattgcgccg cgtcgctatc tactgatact gcacgcatgg ctttccccat
    34081 cttagtcttt tggacaatga cttgtaacaa aatcatcaaa atcaaggaaa tggccaaaat
    34141 cattaactgc acatttgtta agctaattgg tcccaaatca tatcgaactg tttgaatcgc
    34201 ttgagggaag gcacgggtat tggcaccaac cagatagacc attccatact ccaataggaa
    34261 agaaacccca atagccgtaa tcaaaacagc aatacgagta gagtggcgca aaggtcggta
    34321 agcaagaaac tcaatcacga caccaagaat agctgtcgct agcatagcta caataagcgc
    34381 tacaaagaaa ttcatttgga aagaattgat caagaaataa ccgataaagg ctcccatcat
    34441 ataaatatca ccatgggcga agttgatgag cttgataatt ccgtaaacca tggtatatcc
    34501 tagggctaac agcgcgtaaa cactacctag aatcaaacca tttacgagtt gttggagcat
    34561 aagattcact ctttctattt ataattccga ggggtttccc tcactttttg ataggttctt
    34621 atactcaatg aaaatcaaag agcaaactag gaaactagcc acaggttgct caaagcactg
    34681 ctttgaggtt gtagataaga ctgacgaagt cagtcacata tataatccaa ggcgacgttg
    34741 acgcagtttg aagagatttt cgaagagtat taaatatcga aacagggagt gagtcaaagg
    34801 ctcattccct atttcaacat ttttctatta tggttttaca acttctgctg cttcaacttt
    34861 accattgttc atggtcatca tgtaagcagt tttgactgtg ttgtggtctg catcgaagct
    34921 tgtttgacca gttacacctt caaaatcttt tgttttagca aggttatcct tgatttcacc
    34981 tgaattttta gcaccttttg ctgcgtttgc tacaaggtga actgaatcat aagccaaggc
    35041 tgcaaatgtt gaaggctctt cattgtactt agcacggtaa gcgtcaagga aggctttagc
    35101 tttagctgaa acttctacag tagttgagaa gcctgagata aagtagatgt ttgatgcttt
    35161 ttcagcagtt gcttgttgta caaactcctc accgttgaat ccatcaccac caacgattgg
    35221 tttgtcaatt cccatgccac gcgcttggtt tacaatctta ccagcctcat tatagtaacc
    35281 aggaacaacg atagcatcaa agtctttccc tttcattttt gtaagggctg cttgaaagtc
    35341 tgtgtcacct gctacgaaag tttcatctgc aacgatttca cccttgtatg actcgcggaa
    35401 agatttggca atccctttag catagtcact ggcattgtca gtgtaaagaa caactttctt
    35461 agcatttaat ttttcagaaa catagtttga gataattttt ccttggaagc tatcttggaa
    35521 agttccaata aagaggtaat cttgaccttt agtcaatcca tcttgagtcg cacttggtga
    35581 gatcaatgga acacctgctt ttgtagcgtt cgctaccgca gctgcagtcg caccagatgt
    35641 cgcaggtcct acgactgctg atactttaga ttgggttaca aggttagttg taactgaagc
    35701 agcctcagct gtttcagact tattatcttt atcgactact tcgatttgtt ttccatcgat
    35761 accacctgcg gcattgattt catcaacagc caattgggca cctttttgtt cagctgttcc
    35821 gtatgcagct aaagaacctg attcttcaaa gttaaacccg attttaattg tcttttcctc
    35881 tactgagtta ccagcagtgt tgactgctcc agacttcact tctccacagg ctgcaagaag
    35941 tgctacactt gcaagcgcca caaacgatag ggcaaatttt ttcttcatct ttttgtctcc
    36001 ttatttctta aatagtctgt taagaatata ccgaattatc agaaaattgt caatgttttc
    36061 cttgaacttt ttcgatgata acgttttcct atcgataaag attgcccaca aagggtgttt
    36121 ccaactcttg gatatgacaa accctaactt ttttaataaa tttttccttg ctcaagcgtc
    36181 cgaccaattg ctccacttct tgagttggaa catagagttg taagtaacga tgtttcttgg
    36241 aatgataggt aatatctcca taatcctgca gttttttggc atcacgatta tagtaaagat
    36301 agataatcaa gccagagcga ttgacttttt caaacatgat aaatcctctt tctaagaaat
    36361 ctctccctat tataccaaaa aaagcaaacc cagtcgagtt tgccttctat catcattagt
    36421 tcaatgaatt gttggccata atttcatcaa taaagccata ttcaagtgtt tcctgggcgc
    36481 tcatccagtt atcacgttct gcatctgcat ggactttttc cattgactga cctgaatttt
    36541 cagccaagat tttttccaag gtattacgag ttttgagcaa gtgttctgca gcgatagcca
    36601 tatcagtttg ttgggtacca ccacctgtac cgcccattgg ttggtgaatc atgtattcag
    36661 catttggaag catgaaacgt ttgccttttg ccccacttga tgcgatgaca gtccccatag
    36721 atgcagccat tcccataaca atggtttgga catctgcctt gataaagttc atggtatcta
    36781 cgattgccaa accagctgaa acagaaccac ctggtgtatt gacataaagg taaatatctt
    36841 tcgtactatc ttgggcatcc aagaaaagca attgggcaat aacagagtta gccatattgt
    36901 cttcaaccgg acctgtcagc ataatgatgc ggtctttgag aagacgtgag taaatatcgt
    36961 aagaacgttc tccacggctt gtttgttcaa taactacagg aatcattcat ttctcctttt
    37021 gagttttaat tttgttggtc aaatgactga agataagact attataatat cttggtcaaa
    37081 aaaggtcaaa tttttgctct gctttcatta gacagaaaca aaaacccaac ctcctttcgt
    37141 gactagaaat gcttttccaa gtcattcttc ttttcgatct tattttgtac cgaacaagcg
    37201 gtctccagca tctccaagac ctggaacgat ataaccgtgt tcgttcaaac gttcatccaa
    37261 ggctgctgta aagatttcta catctggatg agcttcttga agggctttta caccctctgg
    37321 agcagataca aggcagacaa atttgatatt tgatgcgcca cgttttttaa gagaatcaac
    37381 agccaagatt gctgagccac ctgttgccaa cattgggtct actacaaaaa tttgacgttg
    37441 gtcaatgtcc tcaggcaatt tcaccaagta ttcaactggt tgaagtgttt cttcatcacg
    37501 gtacataccg atgtggccaa ctttagcagc tggaaccaag ctcaagagac catcaaccat
    37561 cccgatacct gcacgcaaga ttgggacgat ggccaatttc ttacctgcca attgtttttg
    37621 aactgttttt gtaattggtg tttcgatttc cacatcttct agtggaagat cacgaagtac
    37681 ttcatacccc atcaacattg caatctcatc tactagctca cgaaaagctt ttgtagaagt
    37741 atctgtacga cgcaagattg acaatttgtg ttgaatcagt gggtgattaa taacttcaat
    37801 ttttcccatt tttggaattc cttctttcaa tttattcttc ttattatacc aaaaaacggt
    37861 ttaaaaatct ttctaaacca tttatttttg ataattttta cattagatca gcctctttaa
    37921 gagctgtctg tactgtctca agtggtaaat gggtcaattc tgtccctttt tcttgataaa
    37981 ggtattgggc gtagtcgtcc attcggtact ggttgatata aaccacgcgc ttgcagccga
    38041 cctgaagcaa ttgttttgta cagttgagac aaggaaaatg ggttacatag gctgtaaagc
    38101 ctttgggaac accacgctca gcaccttgaa ggatagcatt gacctcagcg tgaagggtgc
    38161 gaacacagtg gccttcaatg accaaacatt cgtgatcaat acaatgctca gtccctgaca
    38221 ccgaaccatt gtaaccagtg gaaataacct tattatcttt taccagaatc gcgcccactt
    38281 tagcacgttt acaagtggaa cgattcgcaa ttagtagggc ttgggctgca aaatactcat
    38341 cccaggccag tcttttttca gtcatctctt ttctcctttt tctctatttt ttaaaaaatg
    38401 gtaaacctaa atctgcaatc ttttcagctg gtaccttcat gccatccttg atccatttta
    38461 gaaggacaga gacgatggct gagctccaga aggaatgaag ataagagctg acaccttttg
    38521 atttcccatg gtatttttct agaaattcct gcatggcttg gacaaagatt ttttccagat
    38581 ggtaatccaa ggccaattga attactctag cttcctttct ggtctcccgg aaaaggtgaa
    38641 cccaaaccaa ataaaggtct gtctttaaat cgtaatgatg cagctgttcc ataatattgt
    38701 ggacagttcg tttaaagacg ctctctaaaa tttcctcttt ggagtcataa ttgcgataaa
    38761 aggccgcacg cgaaacacct gcacgtttga ccaattcaga aatactaatc ttggtcagct
    38821 cctttttttc caagagttgc aagagggctg tttcaatggc ttctctggtt aataaattgg
    38881 attcttggtt tgattttctg agattttcaa gagacttttc agagattcta cgttcagaca
    38941 taacattttc tttctacttg tcacaacaga cggatgatgc ttttgtttca agagttttca
    39001 tgatataatt gtaaaaaaag acagaacctt tgtcaatgta taactgacaa agatggagaa
    39061 tttctatgac ttggaagatt attgctgact ctggttgtga ttatcgtcaa ctgccaacac
    39121 cagctattaa cacaaccttt gtaagtgtcc ccttaaccat tcaagtagct gatcaggtct
    39181 ttgttgatga cgccagtctc gatattgacc aaatgatgga aaccatgtat gcaactgcag
    39241 aagcttcaaa atcagcttgt ccaagcccag atgactattt gcgagcattt gaaggtgcca
    39301 aaaacatttt cctagtaacc atcacaggta ccctttctgg cagtcacaat agtgctcaac
    39361 tagcaaagaa tatttatctg gaagaccatc ctgacactaa gattcatgtg attgatagtt
    39421 tatctgctgg tggtgaagtt gacctactcg tagaaaaatt gaatgacttg attgaccagg
    39481 gcttgtcttt tgaagaagtg gttgaagcta tcaccgccta tcaagaaaaa actaagttgc
    39541 tctttgtcct agccaaagtc gataacttgg tgaagaacgg ccgtttgagc aagcttatcg
    39601 gtacggtcgt tggccttctc aacattcgta tggtcggaaa agctagtgaa actgggactc
    39661 tcgaattgct acaaaaagca aggggatcaa agaaatcagt tcaagctgcc tatgatgagt
    39721 tagtaaaagc tggatatgct ggtggccgta ttgtcatggc ccaacgcaat aacgaaaaat
    39781 gttgtcaaca gctctcagag cgaatccgtg aaaccttccc acaagcggat attaaaattc
    39841 taccaacctc tggtctctgc agtttctatg cagaagaggg cggtttgctg atgggctatg
    39901 aaattgatta attgcattct tgacaagagg tgaccatcat ctcttgtttt tttgtggtac
    39961 aatagagcta tgaaacattt tgatactatt gtcatcggtg ggggacctgc tggtatgatg
    40021 gctacgattt ccagtagctt ttatggacag aaaaccctcc tcatcgaaaa aaatcggaaa
    40081 cttggaaaaa aattagctgg gactggtggg ggacgttgca atgtgaccaa caatggtagc
    40141 ttagacaacc tgctagctgg aattcctgga aacggacgct ttctttacag tgttttctcc
    40201 cagttcgata atcatgacat catcaacttt tttacagaaa atggtgttaa acttaaggtc
    40261 gaagaccacg gacgcgtctt tccagccagt gacaagtctc ggactattat cgaagctttg
    40321 gaaaagaaaa tcaccgaact aggtggtcaa gttgctactc aaatagaaat cgtttctgtt
    40381 aaaaaagtag atgaccagtt tgtccttaag tcagcggatc aaaccttcac ttgtgagaaa
    40441 ctcattgtca caacaggtgg taagtcttat ccttcgactg gttcgactgg ttttggtcac
    40501 gagattgctc gccattttaa gcataccatc accgatcttg aggctgctga aagtccttta
    40561 ttaacagatt ttccacataa agccttacaa ggtatttctc tggacgatgt gaccctaagt
    40621 tatggtaagc atgtcatcac tcatgattta ctctttaccc actttggttt gtcaggtcct
    40681 gctgccctac gcatgtctag ctttgtcaaa ggtggggagg ttctctcact cgatgttttg
    40741 cctcaacttt ctgagaagga cttggttaca tttctagaag aaaatcggga aaaatccttg
    40801 aaaaacgctt taaaaacctt gttaccagaa cgcttggccg aattttttgt acaaggatat
    40861 cctgaaaaag tcaaacaact gactgaaaag gaacgagaac aacttgtcca gtccattaaa
    40921 gaacttaaaa ttcctgtaac tggaaaaatg tcccttgcaa agtcctttgt taccaagggt
    40981 ggagtcagtc tcaaggaaat caatcctaaa acccttgaaa gtaagctggt acctggcctc
    41041 cactttgcag gcgaagttat ggatatcaat gcccacacgg gtggctttaa catcacttct
    41101 gccctctgta ccggctgggt ggcgggaagt ctgcattatg attaaagatt aaaggttgtg
    41161 aagaatgaac agaagagagg cagtcgaatt tgttaacatg tgtatgatta aaaacggaga
    41221 taaggtcctg gtccaagacc gagttagtcc cgactggtct ggcattactt ttcctggtgg
    41281 tcatgttgaa cgtggcgaat cctttgtcga tgctgtcatt cgtgaagtga aagaagaaac
    41341 tggtctgatc atttccaaac cccaactctg tggtatcaaa aactggtatg acgacaagga
    41401 ttatcgttat gtcgtccttt tttacaagac agaacacttt actggtgaac tccagtcttc
    41461 agacgaaggg aaagtttggt gggaggactt tgaaaatctt tctcatctaa aacttgcaac
    41521 cgatgatatg tctgatatgc ttcgtgtgtt tctagaagaa gatctcagtg aattctttta
    41581 ctacaaaaac ggtgacgact ggctttatga tttgaagtaa aaaataggct aggaaattcc
    41641 tagcctattt attctgcatt tgtctgaacg taaaccgcaa tggcatctga cgtgtactgg
    41701 gctgtttcag aaccaaactt gtcaatgttt tccttaaact ctgggttgta gacgtaacct
    41761 ttaccgatat gaccgaatac ctcaatagag cagtcaaatc cataagtgcg aatggcttgc
    41821 aagagcttgg ctgcttgctc ctggttttcg gttgctgttg caggtaaacc aacttgaaga
    41881 ttttgtgcca aagtttgaaa gacttggtta aaggcggccg tagcctcgtc ttcgtgacct
    41941 ttttggcgtt cgagcgcttg tcccatgact tcttgaccat atttctctac cgcttcttgg
    42001 tggtattttt gattgtcttg atagctaaat cccgtgaatt tttcctcaat ggtcattttt
    42061 ctttctcctt tttgttcttg aatagttttt tgcaaggtgg aaatcaaggt atccagatgt
    42121 tgcctttcgc gagttagata gtccaactgc ctagtcaaat ggggcaataa atctgtcctt
    42181 tcttccttta acagctctgc tattttctct aaagaaaagc ctagatattt gtagtaaaga
    42241 atgacctgaa ggcgttccaa atcctcttga ctgtaggttc gatagccgtt ttccgacttt
    42301 aaggggacca agagtcctat cttgtcatag tgatgcaggg tcttgacaga gacacctgaa
    42361 agctgcgcag cttcttttat atggtacatg atttcctcct tacaatgata gtataacccc
    42421 tccccttagg tcagagtcaa gcgtttttga gaaaattttt taactttttt gagaaaggtg
    42481 tgaaaacttg aaaatgattt tcttgacaga ccttagaaaa catgatagga tagtcaagtc
    42541 tatcaatcaa acagaaggct atttgacaac tcaagtagct ttttcttatt ttgaaaaagg
    42601 agatcagagt ttaactatgt cagaaaaatc acaatggggg tcgaaacttg gttttattct
    42661 agcatctgct ggctggccat cgggcttggt tccgtttgga agtttcccta catgactgct
    42721 gctaatggcg atggaggctt tttactaatc tttctcattt ccactatttt aatcggtttc
    42781 cctctcctgc tggctgagtt tgcccttggc cgtagtgctg gcgtttccgc tatcaaaacc
    42841 tttggaaaac tgggcaagaa taacaagtac aactttatcg gttggattgg cgcctttgcc
    42901 ctctttatcc tcttatcttt ttacagtatt atcggaggat ggattctagt ctatctaggt
    42961 attgagtttg ggaaattgtt ccaacttggt ggaacgggtg attatgctca gttatttact
    43021 tcaatcattt caaatccagc cattgcccta ggagctcaag cagcctttat cttattaaat
    43081 atctttattg tatcacgtgg ggttcaaaaa gggattgaaa gagcttcgaa agtcatgatg
    43141 cccctgctct ttatcatctt tgttgttatc atcggtcgct ctctcagttt gccaaatgcc
    43201 atggaagggg ttctttactt cctcaaacca gacttttcaa aactgactag cgctggtctc
    43261 ctctatgctc tgggacaatc tttctttgcc ctctcactag gggttacagt catgttgacc
    43321 tatgcttctt acttggacaa gaaaaccaat ctagtccagt caggaatctc catcgtagcc
    43381 atgaatatct cgatatccat catggcaggt ctagccattt tccaagctcg atcccccttc
    43441 aatatccagt ctgaaggggg accgagcttg ctctttatcg tcttgcctca actctttgac
    43501 aagatgcctt ttggaaccat tttctacgtc ctcttcctct ttgcgactgt cacttcttct
    43561 gtcgtgatgc tggagatcaa tgtgggcaat atcaccaacc aggataacag caaacgtgcc
    43621 aaatggagtg ttattttagg aattttgacc tttgtctttg gcattccttc agccctatct
    43681 tacggtgtca tggcggatgt tcacattttt ggtaagacct tctttgacgc tatgaacttc
    43741 ttggtttcca atctcctcat gccatttgga gctctctacc tttcactttt tacaggctat
    43801 atctttaaaa aggctcttgc aatggaggaa ctccatctcg atgaaagagc atggaaacaa
    43861 ggactgttcc aagtctggct cttccttctt cgtttcttcg ttccgtcatt ccaatcatca
    43921 tcgtggtctt catcgcccaa tttatgtaat caaaaaggac ttgagtaatg aactcaggcc
    43981 ctttcttttt tatggatgac taacaattaa ttctaaatct tgcccttcca gagtccaagc
    44041 ttcaacatca cttggtagga taaagtgtct ccctttttgg attggatagt ttttcccgtc
    44101 aacagttagt tgaccttgac cagccaagac actcaacaag ctgtagtcag ctgtcttttc
    44161 aaagttaact tttccagtaa tttcccattt gtaaactgcg aagaaatcat tggatacaag
    44221 gagagtggaa cgtagatcat ctgctttgat tgtcactgga cggctatttg cgggttcacc
    44281 aatgttcaag acatcgatag atttttcaag gtgaagttca cgtaaattgc ccttgtcatc
    44341 cttacggtca aagtcataga cacggtaagt ggtatcgcta gactgctggg tttcaagaat
    44401 caagataccc gccccgatag cgtgcatggt accgcttggt acatagaaga aatctcctgc
    44461 tttaactggc acttttgtca acagcgcatc ccagttctta tcctcgattt gctggcggag
    44521 ttcttctttt gacttggcat tgtgaccgta gataatctct gaaccttcat ccgctgcgat
    44581 aatgtaccag cattctgttt ttccgagttc gccttcatgc tcgagtccat aagcatcgtc
    44641 tgggtgaact tggacactga gccagtcgtt ggcatcgagg atcttggtca aaagtggaaa
    44701 tacaggttct ggacgattgc caaataattc acggtgttcc gcatacaaag tagcaagatc
    44761 tgttccctcg taacgaccat tggcaacttt agagactcca tttggatggg ctgagatggc
    44821 ccaatattct ccgatttttt cacttgggat gtcgtagcca aactcatcac gtagcttggc
    44881 tccaccccag attttttctt gcataactga ttgtaaaaat aatggttctg acatgtcgat
    44941 ctcctgtctg atttttctcc cctcattata gcaaaaaaag agttcgaatt gaactctttt
    45001 ttacatctta taaagcaggg agaagatttt ataaaaatag taaacaaatg tgctctaccc
    45061 gatgcttgca ccattgctat caatgacatc cttgtaccaa tagaaggact tcttcttgct
    45121 acgtttgaga gctccgtttc ctacattatc tcgatctaca tagataaagc catagcgctt
    45181 attcatttcc cctgtgccag ctgaaaccgg atcgatacag ccccaagtcg tataaccaag
    45241 caagtcaacc ccgtcttggt aaatggcatc tcgcatggcc ttgatgtggg cctctaagta
    45301 agtaatccga tagttatctg ctacataacc attctcatcc ggtgtatcca tagcaccgag
    45361 tccattttct acgataatac taaactaaaa tcaaaaagca ttatataata gt
//
LOCUS       DBEJZV010000018        43442 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.18, whole genome shotgun sequence.
ACCESSION   DBEJZV010000018 DBEJZV010000000
VERSION     DBEJZV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 43442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43442
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.18"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..305
                     /locus_tag="ACL3S0_001195"
     CDS             <1..305
                     /locus_tag="ACL3S0_001195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312106.1"
                     /translation="VVDGTDEVSSKHCFEVVDRTDEVSNHIYGKVKLTWFEEIFEEYK
                     SLHNKTHITKVLMNCTPKVRQKKSNFLGSIHSTPDTMRFFNFKDFLQLLLTHIKLF"
     gene            complement(347..604)
                     /locus_tag="ACL3S0_001196"
     CDS             complement(347..604)
                     /locus_tag="ACL3S0_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="HGR1312107.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDCDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(754..1608)
                     /locus_tag="ACL3S0_001197"
     CDS             complement(754..1608)
                     /locus_tag="ACL3S0_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR1312108.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWNIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            complement(1816..2853)
                     /locus_tag="ACL3S0_001198"
     CDS             complement(1816..2853)
                     /locus_tag="ACL3S0_001198"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGR1312109.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            complement(2969..4135)
                     /locus_tag="ACL3S0_001199"
     CDS             complement(2969..4135)
                     /locus_tag="ACL3S0_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR1312110.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            complement(4388..4792)
                     /locus_tag="ACL3S0_001200"
     CDS             complement(4388..4792)
                     /locus_tag="ACL3S0_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR1312111.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            complement(4799..5614)
                     /locus_tag="ACL3S0_001201"
     CDS             complement(4799..5614)
                     /locus_tag="ACL3S0_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR1312112.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            complement(5601..6506)
                     /locus_tag="ACL3S0_001202"
     CDS             complement(5601..6506)
                     /locus_tag="ACL3S0_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR1312113.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            complement(6534..7010)
                     /locus_tag="ACL3S0_001203"
     CDS             complement(6534..7010)
                     /locus_tag="ACL3S0_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1312114.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            complement(7007..8794)
                     /locus_tag="ACL3S0_001204"
     CDS             complement(7007..8794)
                     /locus_tag="ACL3S0_001204"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGR1312115.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            9143..9859
                     /locus_tag="ACL3S0_001205"
     CDS             9143..9859
                     /locus_tag="ACL3S0_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR1312116.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            10174..14112
                     /gene="strH"
                     /locus_tag="ACL3S0_001206"
     CDS             10174..14112
                     /gene="strH"
                     /locus_tag="ACL3S0_001206"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGR1312117.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPATEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIEQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAVTHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(14167..15465)
                     /gene="purB"
                     /locus_tag="ACL3S0_001207"
     CDS             complement(14167..15465)
                     /gene="purB"
                     /locus_tag="ACL3S0_001207"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGR1312118.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(15528..15755)
                     /locus_tag="ACL3S0_001208"
     CDS             complement(15528..15755)
                     /locus_tag="ACL3S0_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR1312119.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            complement(15765..16856)
                     /gene="purK"
                     /locus_tag="ACL3S0_001209"
     CDS             complement(15765..16856)
                     /gene="purK"
                     /locus_tag="ACL3S0_001209"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGR1312120.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLISNEPDSVDELGEGIDF"
     gene            complement(16843..17331)
                     /gene="purE"
                     /locus_tag="ACL3S0_001210"
     CDS             complement(16843..17331)
                     /gene="purE"
                     /locus_tag="ACL3S0_001210"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGR1312121.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPIIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAAIFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            complement(17361..17477)
                     /locus_tag="ACL3S0_001211"
     CDS             complement(17361..17477)
                     /locus_tag="ACL3S0_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR1312122.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            complement(17734..18996)
                     /gene="purD"
                     /locus_tag="ACL3S0_001212"
     CDS             complement(17734..18996)
                     /gene="purD"
                     /locus_tag="ACL3S0_001212"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGR1312123.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVIYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTVATVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            complement(19118..20665)
                     /gene="purH"
                     /locus_tag="ACL3S0_001213"
     CDS             complement(19118..20665)
                     /gene="purH"
                     /locus_tag="ACL3S0_001213"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGR1312124.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFSDNVEEIAKAGIKAIIQPGGSVRDQESIEAANKYGLTMVFT
                     GVRHFRH"
     gene            complement(20690..21199)
                     /locus_tag="ACL3S0_001214"
     CDS             complement(20690..21199)
                     /locus_tag="ACL3S0_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR1312125.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            complement(21283..21828)
                     /gene="purN"
                     /locus_tag="ACL3S0_001215"
     CDS             complement(21283..21828)
                     /gene="purN"
                     /locus_tag="ACL3S0_001215"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGR1312126.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            complement(21825..22847)
                     /gene="purM"
                     /locus_tag="ACL3S0_001216"
     CDS             complement(21825..22847)
                     /gene="purM"
                     /locus_tag="ACL3S0_001216"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGR1312127.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            complement(22884..24326)
                     /gene="purF"
                     /locus_tag="ACL3S0_001217"
     CDS             complement(22884..24326)
                     /gene="purF"
                     /locus_tag="ACL3S0_001217"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGR1312128.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            complement(24419..28144)
                     /locus_tag="ACL3S0_001218"
     CDS             complement(24419..28144)
                     /locus_tag="ACL3S0_001218"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGR1312129.1"
                     /translation="MDKRIFVEKKADFQVKSESLVREFQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTTQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            complement(28201..28344)
                     /locus_tag="ACL3S0_001219"
     CDS             complement(28201..28344)
                     /locus_tag="ACL3S0_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGR1312130.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            complement(28346..29053)
                     /gene="purC"
                     /locus_tag="ACL3S0_001220"
     CDS             complement(28346..29053)
                     /gene="purC"
                     /locus_tag="ACL3S0_001220"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGR1312131.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            complement(29223..30572)
                     /gene="comB"
                     /locus_tag="ACL3S0_001221"
     CDS             complement(29223..30572)
                     /gene="comB"
                     /locus_tag="ACL3S0_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGR1312132.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATIEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            complement(30585..32738)
                     /gene="comA"
                     /locus_tag="ACL3S0_001222"
     CDS             complement(30585..32738)
                     /gene="comA"
                     /locus_tag="ACL3S0_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGR1312133.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            complement(33118..33609)
                     /locus_tag="ACL3S0_001223"
     CDS             complement(33118..33609)
                     /locus_tag="ACL3S0_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312134.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            complement(33590..34186)
                     /locus_tag="ACL3S0_001224"
     CDS             complement(33590..34186)
                     /locus_tag="ACL3S0_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1312135.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            complement(34183..34665)
                     /locus_tag="ACL3S0_001225"
     CDS             complement(34183..34665)
                     /locus_tag="ACL3S0_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HGR1312136.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            complement(34662..35802)
                     /locus_tag="ACL3S0_001226"
                     /pseudo
     CDS             complement(34662..35802)
                     /locus_tag="ACL3S0_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(35809..36105)
                     /locus_tag="ACL3S0_001227"
     CDS             complement(35809..36105)
                     /locus_tag="ACL3S0_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HGR1312137.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(36648..37541)
                     /locus_tag="ACL3S0_001228"
     CDS             complement(36648..37541)
                     /locus_tag="ACL3S0_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1312138.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(37562..37756)
                     /locus_tag="ACL3S0_001229"
     CDS             complement(37562..37756)
                     /locus_tag="ACL3S0_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312139.1"
                     /translation="MKKVLKYFLVFVFLFLMNIFIFKILATLGFQLIMSEKSYIVLPL
                     FSLIVLYMIDKRIRKKKKSL"
     gene            complement(38167..38292)
                     /locus_tag="ACL3S0_001230"
     CDS             complement(38167..38292)
                     /locus_tag="ACL3S0_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR1312140.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            complement(38295..38525)
                     /gene="blpU"
                     /locus_tag="ACL3S0_001231"
     CDS             complement(38295..38525)
                     /gene="blpU"
                     /locus_tag="ACL3S0_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGR1312141.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            complement(38728..39018)
                     /locus_tag="ACL3S0_001232"
                     /pseudo
     CDS             complement(38728..39018)
                     /locus_tag="ACL3S0_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(39064..39297)
                     /locus_tag="ACL3S0_001233"
     CDS             complement(39064..39297)
                     /locus_tag="ACL3S0_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR1312142.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(39303..40295)
                     /gene="plsX"
                     /locus_tag="ACL3S0_001234"
     CDS             complement(39303..40295)
                     /gene="plsX"
                     /locus_tag="ACL3S0_001234"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGR1312143.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPMRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTIDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(40292..41062)
                     /gene="recO"
                     /locus_tag="ACL3S0_001235"
     CDS             complement(40292..41062)
                     /gene="recO"
                     /locus_tag="ACL3S0_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGR1312144.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQNLTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(41059..42228)
                     /locus_tag="ACL3S0_001236"
     CDS             complement(41059..42228)
                     /locus_tag="ACL3S0_001236"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR1312145.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            42377..43387
                     /locus_tag="ACL3S0_001237"
     CDS             42377..43387
                     /locus_tag="ACL3S0_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGR1312146.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
BASE COUNT        13060 a         9944 c         8002 g        12436 t
ORIGIN      
        1 aggttgtgga tggaactgac gaagtcagct caaaacactg ttttgaggtt gtggatagaa
       61 ctgacgaagt cagtaaccat atctacggca aggtgaagct gacgtggttt gaagagattt
      121 tcgaagagta taagtctcta cataataaaa cgcatattac caaggttctt atgaactgca
      181 ccccaaaagt tagacagaaa aaatctaact ttttggggtc aatacattca acacctgata
      241 ctatgcgttt ttttaatttt aaagattttt tacaacttct tttgactcac attaaactat
      301 tctaatagtt aatagacctt tgcacatatc gtctcaaaac attcatttat ttccgtttaa
      361 tcaagtatcg gatagccttt tctaggcgtt ccttttgagc ttcagaatca tctagtggct
      421 gattgataca ttcagtaaga ttttcggtaa ttatcatctc aatcacgcgc tctacactag
      481 atctcactgc tgtcagttgc gtcacaatat cagcacagtc acaatctcct tcaatcatct
      541 tttgaatccc acacaactgg ccctctgaac gtttcaaaca agtaatatac tttgaatttg
      601 tcatttcttt ttccttgctc gatttttctt cattatatct ctaatcagct tctttgtcaa
      661 aattctcacc catccagctc acgcagttct gttaccaaag accgttcaaa aagcaaacta
      721 gcaatactta taacttatta aaaattccta attttacctt gctaaacgaa tacgggtcac
      781 gatgccatct gagtctgtga tttccaattg gatcgatgtc atccatttga ttggtgcgtc
      841 aacttcttgt gctcgttggg caatcgttaa cagttctttt ttatgtgcga cttcgatgac
      901 atagtaggct aaacctggta agccttgctt acgcgaagcc agaccttttc ctccccattc
      961 gttaactgct aaatgatgat ggtaatctcc agccgcaatc caactagcgc caggcacact
     1021 gaatttattc tctagcccta acaccttttg ataaaactgg ctggactttc gactatcctt
     1081 gacggaaaga tgaatatgcc ccattcttgt accttctgcc aggataaagg gctctactct
     1141 ttcccccaac tcataaatgt cctgcgccgc aagagcctcc gtcactccga taatgcgtcc
     1201 atcttctcga atattccatg tggaaactgg cttatctcga tagagttcaa tgccatttcc
     1261 ctccaaatct tccaagtaaa tagcttcact gtaaccatgg tctgcaccgc cgacaagagg
     1321 aatttgcaaa tctgtcaggt gtttcaagac atcagccaaa gccttgcgtg tgggcaagag
     1381 aatggccaaa tggtaaagac cataatgttc cctcacttct ccgctctctt gtgcttgaat
     1441 cagctgtacc aagacttttc caccaaggcc tagaatggac tctgtctcag tttgagataa
     1501 gatttctaaa ccaataactt gctgataaaa ggctgtttga ctggccaaat cctttacatt
     1561 taaaactgtc tctgccaaat aaatgtgact cttgtattca taggtcataa atggtcctct
     1621 tttctcgttg taattattgt tattacaact attatataat ttccatcaag aaagtcaagc
     1681 cagataactc aaaaataaca ccatttcagg ataagataaa gtaaatcatt tcataataaa
     1741 acgcatatta tcaaactttt catcacctga caatatgcgt tattttaatt ttaaagactt
     1801 tttgaccagc tttttttatt tcacaacaag ttcataacgt gtcttactgg tgaaggtttg
     1861 accagcttta agaatgactt ggcctttaag gtcactgtga atggcatctg gtaaagcttg
     1921 cgcttcaaga gcaatcccat tgtgctgtag cattggctga cctcctatga tgacactttc
     1981 atccacaaag tttgctgtgt agaccacaaa gcaaggagct tctgtcttga aaagcaggaa
     2041 gcgacctgaa ttttggtcat aaaggaatcc agcattgtca tggcctgcag gaagggcaaa
     2101 tgggtgatcc aaacctgatg ccagctggat ttgctcatct tcttctgcaa agatatcctt
     2161 caacaaggta ccattgtaga tgtgtttgac cacatcacgg ttggcttctg gagttttggc
     2221 aggaacaccg tcaggagcga ttgagtaaat gccctctgtg tttagttgga agacatgacg
     2281 gtcaatcgtc tgcgtgaaat caccagacaa gttgaaatag ctgtggttgg ttggattgac
     2341 cagcgtatcc tgatcggtcg ttaccttgta gatgatttca taggcaccag tttcttccaa
     2401 gtgataactg atccaaatct tgagatttcc agggaaccct cctgtcccat ctgtacgctc
     2461 tgtgtagaga gtcaagccat gatcgcttac ttcttcaact tcaaacaagc tggaatccca
     2521 accagttgaa ccactgtgat tacagttgct agcattatta acctcaaggt cataggtctt
     2581 accattgagc tcaaaggtcg cacctgcaat acgacccgct acaggaccta cacttgctcc
     2641 atgcttggga ctattgccta cataactatc aaagtcatca aatcccaaga taacattggc
     2701 aaaatttcca gccttgtcag gtgcgacata gcgcaagatg gtcgcgccat aagtcataac
     2761 ctcaagttgg tagccaccgt ctgtctcaaa tcgataggcc aagacatcct cgccctcaac
     2821 atttccaaat acacgctctg tgtatgcttt cattctgttc tccttttact atttctctca
     2881 agcaaacaaa ccatagaaag cgtactgaca atctatggtt tatctgataa tttacaaatc
     2941 ctcttgtcaa gaattcataa acactgtctt acttttgata ttcgtgaatt atgacacctt
     3001 gtactacacg gtttactgta cctgtaggag acggtgtatc tggtttattt tctaccttga
     3061 gtgaagtcaa tagagcaaag agttgggcat aaacgatgta agggaagaca cggtaaatat
     3121 cattcaagac accgccacaa ccaaggacca cttctttgac attttcaaga ccaaaagctt
     3181 gatcactcaa aagcacaaca cgacgagcaa tctggtcacc agcaacttca cgaaccaagt
     3241 ccaagtcgta cttacgagtg taggctgtcg ttgtaccaaa gaccaaaaca actgtattgt
     3301 cgttgataag agattttgga ccgtgacgga agccaactgg gctttcatac atggtcgcaa
     3361 cttgaccagc agttaattcc aaaatcttga gctgagcttc atgagcaagt ccaaagaaag
     3421 gaccagcgcc tagatagatg acacggttaa agtctaaatc aacgagctct ttgacatctt
     3481 ctaccttgtc taaaacttta cgggcaagac tagatacaac ttcaaaacgt tcagacttaa
     3541 cagcaaattc tgtaggatca aagaccaaga gagctgtcaa catcatagac gtaaagctag
     3601 aagtcatggc aaatccagca tcattagaga cagctggttg caagagcaag agattacggt
     3661 catcaccgtg agcttgaaga gccaatttac catctgctgc acaagtaatc gtcacttgat
     3721 aaagctcatc caccaaggat ttggccaaat caacagtcgc cacactttca ggcgagttcc
     3781 cactacgagc aaaagacaca aggacagttg ccacatcttt tttcaaatag gttgctggtt
     3841 tggcaacgat atctgttgtc gcaatagcat tgaaattcca tttgcgttcg tcatagactt
     3901 ccttaaagta aggtagcaag gtatctccca cataagcaga agtcccagca cctgtcaaga
     3961 taaccttaat atagtcatgt ttatcagcga tttcttgtag aaaggctgca atttcttcac
     4021 gttttgcttg ataaaattca aaagcttctc tccatacatc aggctgttgg tagatttcac
     4081 gcgtagtgat ttctgcaccc aattcgagca agtcttcttt tgtataatgt agcattgagt
     4141 tcctcttttt ctattaaata tgggaatggg agtaagctcc attcccatgt atattctata
     4201 taaaatgctc taacgatttt cacgttgtca catgaattga atcgagttcc aactaaaatc
     4261 tgtaggaaac tagccgcagg ctgctcaaag caccgctttg aggttgccgg ataagactga
     4321 cgaagtcagt aacatatacc tacggcaagg cgacgttgac gtagtttgaa gagattttcg
     4381 aagagtatta ttcatcttcg tcatcatcga agcccgctaa caggtcatta actttcacaa
     4441 tgctttctgc agcacggctc ttgtagtccg catctgcgcc tgtaaggctc gcattgataa
     4501 attcaatcac cattggaaga ttcatccctg cgtaaaggtc aatatcacga ccttccatga
     4561 tcaagcgact caccacatta caaggtgtcc caccgagaag atccgcaaag actaggaaat
     4621 catccaatcc ttcaataaca gcttcaaatt tagcagtaaa ttcttctggg ccatcttctg
     4681 gaagaagagc tactgtgtaa atgttgtctt gtgggcccat aatcatttct gtgctacctc
     4741 taagctcctc acagaagcga ccatggctca ccaaaattaa tgatttagtc ataaggaatt
     4801 acattccaag tgcaaagtga ccaagggcag aaagagccaa agcaagtacg ataataatac
     4861 cgatagcttt agtagagttc ataccttttt taccaagcaa ccagaagata aaggcagtaa
     4921 agattgctgg aagcaaacgt gggaagattt ggttcaagat gtcttggaaa tcaatcatct
     4981 tttcaccgat tggcaacttg taagaaattt caaagttaat cactgttgct acaagagcac
     5041 ccatcatgaa gacaccaagt acagatgcag cgtcaatcaa agctgtcaag gtactttgca
     5101 tgttgttgat aaggttaacc ccttctttgt aagcaaattc caactgtttc caacggaaga
     5161 tgtcatacgc tactgcaact gcaatccaaa ggaagatccc ccaaggttgg ccagcgatag
     5221 ccatagttgc tgcgactgac cccatgatag caggtacaag tgaaccaaag attgtatccc
     5281 caagaggagc gaatggtccc atcaaacctg tcttgatacc gttaacagcg tcttttgaac
     5341 ctacaccatc tttttcttcc atggcaaggt caaaaccagc gataatggta tggaagaatg
     5401 gtgaagtatt gaagaattga gtatgaactt tcatcatttc tttcaattca ggagttccat
     5461 caccatacat tttacgcaac tgaggcaaga tcatgtaaag gtaaccagaa gcttgcatac
     5521 gttcgtagtt ccaacctaat tggaaagtaa acaagctacg tttgttgatt tgattaaaat
     5581 cttcttttgt aagtttgtaa ttagaattcg tcatcttcga tttccccact ttctgatggt
     5641 gtagaaggtg ctgctacagc tactttttgg ctatttttga agtgaagcac tgcaaggaaa
     5701 atacctacga tagaaatacc aatcatagac aaacctttga agttgttcac gaaaccaatt
     5761 ttttcagcaa cttcagcagg aagagtacct acgataccag caacagcgcc accaagacct
     5821 gttacatatg agtaaagaac agtcaacata gctgtcaaac caaatcccat agcaaggtag
     5881 tgaaggttac gtttaactgg aaggtaacga agcaagattg caaatccaag acctggaagc
     5941 atacgtcctg cgagtgtcaa gccatctgca acccatttgt aggcttcaac gaagtctact
     6001 actgattgta caaaggcacc accaaaagca agggcaaaga agactggaag ggcacgagat
     6061 agagcccacg gaatcgcacc aagcaagtag ttgcgttcaa tacctttata gtcaaagcgt
     6121 tcgattgcag catccacacg gtgagcgaag aaggtagtag tcatacgacc aagaacgtcg
     6181 aagtaagtca agagagctgc tactggtaca gcgattgtag taattgcaag cggtgcatca
     6241 attccttgtg aaacagagaa ggctgtcgca agaaccgcac cagaagttgc gtcgatacga
     6301 gaagcaccac cgaaggtacc aaccccaaga acgaacagtt gcaagttacc accgataagt
     6361 aaaccagtag tcacatctcc catgattaaa ccagtaatga aaccagcaaa tacaggggaa
     6421 cctgcagatg aaacgatcgt caactcatca cagatttgat aagctgagta caaagtgaga
     6481 agtaaaattt gccaccattg tatcataaca atgacctcct aaaaaatttt ttcctatttt
     6541 aataagctca aaaagtctga aattggatca tttggaacca tctgagcagt aagtttaaca
     6601 cctttttctg ccagtttgtg gaagtcttcc acatccttgt ctactacgtt gatagaacgt
     6661 gtaatagaac gagtttctgg tgtttgagac atattcccaa cattaagggt ttcaagtggt
     6721 acacctgctt ctaccaaacc aaggaagcgg tctggtttac gagccacgat aaagagacgt
     6781 tggctatcgt atttgccagc aagaatattg gctgcagctt tctcaactgg caaaatactc
     6841 aatttcacac ctggtggtgt cgcaagtttc aaaccactct tttcaatatc gttgttgaca
     6901 acttcgtcgt ctacaaccat aatgcgtgaa acatttagtt ttccagccca aagattggct
     6961 acttgtccgt ggatcaaacg tccatcaata cggcatccta caattgtcat aagttttccc
     7021 cctttatatg ttttagtgta ggtttacgag ttaaatgaat ctcttcttta tattgacctt
     7081 ctgtttcaaa gataatgatg cggttggcac cttccttgag atagctatga gggatataaa
     7141 gtgagagagt tgggccaacg ttccaaaaac gtcctagatt ctgcccattg acaaaggcaa
     7201 cccccttacc aaactcagac aagtctaggt aagtatcttt tggctcttcg actgtaaagt
     7261 cataagcgta aaaggctggt tgtccttgag tccatccttt tgaaaaatca attttctcag
     7321 gattgtctag tgggagtgga tagtgtttcc agtttagtaa gaaatgcaga tccttacaga
     7381 cccctgtccg aattccctta cgttgcgtat ccgctaagaa cttatgccca tagttgacac
     7441 gccccatatt ttctatcaag atatctaacc tagatagccc tttcttttta ccttgataaa
     7501 aaatatcttc cccaatctct gtctgatatt gagttttaac ccactgacca tcgacataca
     7561 gctgggccct atctcgacca tcaatgatac gaagtctttc ttcttctgca tcccagtttg
     7621 tttctgttcg ataaagtagg tagccataac tttgtcccag ctcctccatc ttttgaggat
     7681 agagactttc tacaggactt gacaagctat ctaaggtttc aaacaaagaa actttttcaa
     7741 ctagtggaat agcatccaac tccatactct ctttgtagag tggttccaac tgcggatact
     7801 ctgaaaaatg tgttgccatc atcttcttga ctgcaagata tttagcagtt ggatttcctt
     7861 cttcatccag aagggcatcg taatcataag acgtaacttg tggcaggtcc aaagttcctc
     7921 gagccgagca accattcatg aaaccaaagt ttgtaccacc gtgaaacatg taaagattga
     7981 tggagccttg ttccaaaact tctcgaactg catctgccaa ttccttagga tcccgtgtga
     8041 taatcggttc tttccaacga ttaaaccaac catcccagaa ctccatacac atgagtggcc
     8101 atttcttacc atgttcatca aagaattcct gcatctgcga aaagttgtaa ggtgccttag
     8161 aaccaaagtt tcctgttaca aagaggtcct cttcaattaa ggttccagct ttcagagtag
     8221 ctcgccatgg accatctgat gtaaagaggg gacaggttac gccacactct tccattagct
     8281 gtcgaatcgc tctcaggtaa gccttatctt ctccgtaaga accatactca ttttcaacct
     8341 gcatcatgag aatattgcca ccattgtcca acaaacgagg aaccagtctt ggcaataact
     8401 gatcatagta gcgaccaact gcctcgatat atgctgggtc ggatgagcga attcgcatgt
     8461 tcttggtcaa gagccaagct ggtaagccac cgaattccca ttccgcacag ataaatggag
     8521 acggacgcac aattgcgtag agacccaaat cctgcgctat ttggagaaat ttctctaaat
     8581 ccagatcacc gtcaaaatga aactcacctt cacgaggctc gtgtaaattc caagcaacat
     8641 aagtctctac cgtattaaaa ccaagagcct tcaagttata gagcgaatga taccaatcct
     8701 ctggaggaac cctaaaataa tgaatggcac cagataaaat cttaaatgat tttccatcga
     8761 gatagaaatc atctcgtatc tcaaatcgtg tcataaaact accttccgac cgcgaaagtt
     8821 tgcgctttca tttgttgtta tattaattat aaaccaatct gtttgaattg tcaatagaaa
     8881 ttgtcgggat atttactgca tttttactat tatacacaca ttcaattagt ttcaaacatt
     8941 tttagaccca tttcaaacgc tctttaaatt cggaatatag gacctaaaat aattttgtat
     9001 agaatacatt tataaaatat gagcaatccc tatatcgctt aatttttcaa actattattc
     9061 taatttttta ttcaaaagac tactattttt ttcgctttta tggtaaaatt ttctatggaa
     9121 gaaggaaaat agaggtaaaa atatggcaat tcccaaatat caatacataa aagacgaatt
     9181 aaaaaataaa atcatctctg ggcagtttag cagtggagat aaattttaca ctgaagcaga
     9241 actcatttca atgtacgatg tcagctctat cacagttgtt cgcgccttaa acgaccttgc
     9301 caaagatggc tatattgtcc gccaacaagg aaaaggaacc ttcgtttcac gtgcacgcaa
     9361 acacaagctt gtagagtttt cagatattga actcttcaat gctaaagatg ataaggtaac
     9421 tgttctttca attgaacgcg gaaacaagct tgtttacttg gaaaaattgg gtctacgcgg
     9481 cgatcaattc tactacaaga ttgaacgtat ccgcgaatca aacggtgtcg tttatatcta
     9541 ccatacatcc tacatcccag aacaatatat caacgcaaat tatccaaacc ttgaatacta
     9601 tagttctatc tataatcgtt tcaagttaga ctaccacatt cacatgaatg atgaacactt
     9661 tgaagaaatc aacgaaatag tctttccaac tccagaacat gcagcttcag tcctcggagt
     9721 cgatgaacaa ttccctactg tcctacaaac taaaatcacc aaactcgaat caactggcca
     9781 agttttagaa tacagtgaaa cttacaaacg atctgattac tacaagatta aatttatctc
     9841 atgtgaccgt gatcactaag aagaaaacct gagctaatcg cttgggcttt ttctatgctt
     9901 attatactac accaaaaagg tagcgcttac ctatttttgg aaaattctat aatttgtgga
     9961 atattttata gaaatagaac caaaaattat actagatata tatacgtatt ttttccgacc
    10021 aatctgaaat cttaagttta aattttatat ttttttatac ttattatagt tttttgtcat
    10081 ctcctcttga ctctcgttaa tataagaaat aaaataaagg cgttgattta tataatcgct
    10141 atcaatataa caatgcaatc aggaggtttt gcaatgaaac atgaaaaaca acagcgtttt
    10201 tctattcgta aatacgctgt aggagcagct tctgttctaa ttggatttgc cttccaagca
    10261 cagactgttg cagccgatgg agttactcct actactacag aaaaccaacc gaccatccat
    10321 acggtttctg attcccctca atcatccgaa aatcggactg aggaaacacc taaagcagtg
    10381 cttcaaccag aagctccaaa aactgtagaa acagaaactc cagctactga taaggtagct
    10441 agtcttccaa aaacagaaga aaaaccacaa gaggaagtta gttcaactcc tagtgataaa
    10501 gcagaagtgg taactccaac ttctgctgaa aaagaaactg ctaataaaaa ggcagaagaa
    10561 gctagcccta aaaaggaaga agcgaaagag gttgattcta aagagtcaaa tacagacaag
    10621 actgacaagg ataaaccagc taaaaaagat gaagcgaaag cagaggctga caaaccggca
    10681 acagaggcag gaaaggaacg tgctgcaact gtaaatgaaa aactagcgaa aaagaaaatt
    10741 gtttctattg atgctggacg taaatatttc tcaccagaac agctcaagga aatcatcgat
    10801 aaagcgaaac attatggcta cactgattta cacctattag tcggaaatga tggactccgt
    10861 ttcatgttgg acgatatgag catcacagct aacggcaaga cctatgccag tgacgatgtc
    10921 aaacgcgcca ttgaaaaagg tacaaatgat tattacaacg atccaaacgg caatcactta
    10981 acagaaagtc aaatgacaga tctgattaac tatgccaaag ataaaggtat cggtctcatt
    11041 ccgacagtaa atagtcctgg acacatggat gcgattctca atgccatgaa agaattggga
    11101 atccaaaacc ctaactttag ctattttggg aagaaatcag cccgtactgt cgatcttgac
    11161 aacgaacaag ctgtcgcttt tacaaaagcc cttatcgaca agtatgctgc ttatttcgcg
    11221 aaaaagactg aaatcttcaa catcggactt gatgaatatg ccaatgatgc gacagatgct
    11281 aaaggttgga gtgtgcttca agctgataaa tactatccaa acgaaggcta ccctgtaaaa
    11341 ggctatgaaa aatttattgc ctacgccaat gacctcgctc gtattgtaaa atcgcacggt
    11401 ctcaaaccaa tggcttttaa cgacggtatc tactacaata gcgacacaag ctttggtagt
    11461 tttgacaaag acatcatcgt ttctatgtgg actggtggtt ggggaggcta cgatgtcgct
    11521 tcttctaaac tactagctga aaaaggtcac caaatcctta ataccaatga tgcttggtac
    11581 tacgttcttg gacgaaacgc tgatggccaa ggctggtaca atctcgatca ggggctcaat
    11641 ggtattaaaa acacaccaat cacttctgta ccaaaaacag aaggagctga tatcccaatc
    11701 atcggtggta tggtagctgc ttgggctgac actccatctg cacgttattc accatcacgc
    11761 ctcttcaaac tcatgcgtca ttttgcaaat gccaacgctg aatacttcgc agctgattat
    11821 gaatctgcag agcaagcact taacgaggta ccaaaagacc tgaaccgtta tactgcagaa
    11881 agcgtcacgg ccgtaaaaga agctgaaaaa gctattcgct ctctcgatag caaccttagc
    11941 cgtgcccaac aagatactat tgaacaagcc attgctaaac ttcaagaaac tgtcaacaac
    12001 ttgaccctca cgcctgaagc tcaaaaagaa gaagaagcta aacgtgaggt tgaaaaactt
    12061 gccaaaaaca aggtaatctc aatcgatgct ggacgcaaat actttactct ggaccagctc
    12121 aaacgcatcg tagacaaggc cagtgagctc ggatattctg atgtccatct ccttctagga
    12181 aatgacggac ttcgctttct actcaatgat atgaccatta ctgccaacgg aaaaacctat
    12241 gctagtgatg acgttaaaaa agctattatc gaaggaacta aagcttacta cgacgatcca
    12301 aacggtactg cactaacaca ggcagaagtg acagagctaa ttgaatacgc taaatctaag
    12361 gacattggtc tcatcccagc tattaacagt ccaggtcaca tggatgctat gctggttgcc
    12421 atggaaaaat taggtattaa aaatcctcaa gcccactttg ataaagtttc aaaaacaact
    12481 atggacttga aaaacgaaga agcgatgaac tttgtaaaag ccctcatcgg taaatacatg
    12541 gacttctttg caggtaaaac aaagattttc aactttggta ctgacgaata cgccaacgat
    12601 gcgactagtg cccaaggctg gtactacctc aagtggtatc aactctatgg caaatttgcc
    12661 gaatatgcca acaccctcgc agctatggcc aaagaaagag ggcttcaacc aatggccttc
    12721 aacgatggct tctactatga agacaaggac gatgttcagt ttgacaaaga tgtcttgatt
    12781 tcttactggt ctaaaggctg gtggggatat aacctcgcat cacctcaata cctagcaagc
    12841 aaaggctata aattcttgaa taccaacggt gactggtact acattcttgg tcaaaaacca
    12901 gaagatggtg gtggtttcct caagaaagct attgagaata ctggaaaaac accattcaat
    12961 caactagctt ctaccaaata tcctgaagta gatcttccaa cagtcggaag tatgctttca
    13021 atctgggcag atagaccaag cgctgaatac aaggaagagg aaatctttga actcatgact
    13081 gcctttgcag accacaacaa agactacttt cgtgctaatt ataatgctct ccgcgaagaa
    13141 ttagctaaaa ttcctacaaa cttagaagga tatagtaaag aaagtcttga ggcccttgac
    13201 gcagctaaaa cagctctaaa ttacaacctc aaccgtaata aacaagctga gcttgacacg
    13261 cttgtagcca acctaaaagc cgctcttcaa ggcctcaaac cagctgtaac tcattcagga
    13321 agcctagatg aaaatgaagt ggctgccaat gttgaaacca gaccagaact catcacaaga
    13381 actgaagaaa ttccatttga agttatcaag aaagaaaatc ctaacctccc agccggtcag
    13441 gaaaatatta tcacagcagg agtcaaaggt gaacgaactc attacatctc tgtactcact
    13501 gaaaatggaa aaacaacaga aacagtcctt gatagccagg taaccaaaga agttataaac
    13561 caagtggttg aagttggcgc tcctgtaact cacaagggtg atgaaagtgg tcttgcacca
    13621 actactgagg taaaacctag actggatatc caaaaagaag aaattccatt taccacagtg
    13681 actcgtgaaa atccactctt actcaaagga aaaacacaag tcattactaa gggcgtcaat
    13741 ggacatcgta gcaacttcta ctctgtgagc acttctgccg atggtaagga agtgaaaaca
    13801 cttgtaaata gtgtcgtagc acaggaagcc gttactcaaa tagtcgaagt cggaactatg
    13861 gtaacacatg taggcgatga aaacggacaa gccgctattg ctgaagaaaa accaaaacta
    13921 gaaatcccaa gccaaccagc tccatcaact gctcctgctg aggaaagcaa agctcttcct
    13981 caagatccag ctcctgtggt aacagagaaa aaacttcctg aaacaggaac tcacgattct
    14041 gcaggactag tagtcgcagg actcatgtcc acactagcag cctatggact cactaaaaga
    14101 aaagaagact aagtcttttc gataaaaaat aaacagcgag attgaagctc gctgtttatt
    14161 ttttaattaa tcacctagtc caagacgttc aaagatatca tccactcgtt tggtgtaata
    14221 aactgggttg aagatttcat cgatttcttc ttgtgtgaga cgtgatgtta cttctgaatc
    14281 tgcctcaaga agtggtttaa agtctacttg gttgtcccaa gagtaggctg tttttggttg
    14341 caccaagtca taggcttgct cacgggtcat gcctttttca atcaatgtca acatagcccg
    14401 ttggctaaag ataagaccaa aagtcgagtt catgtttcgg atcatatttt ctgggaagac
    14461 tgtcaagttc ttgacgatat ttccaaaacg gttgagcatg tagtcaatca aaatggtcgt
    14521 atctggtgtg atgatacgct cagctgatga gtgagaaata tcgcgttcgt gccagagagc
    14581 gacgttttca taagccgtaa tcatgtgacc acgaatgaca cgcgccagac cagtcatatt
    14641 ttcagaaccg attgggttgc gtttgtgagg cattgctgaa gacccttttt gccctttagc
    14701 aaagaactct tctacttcgc gttgctcaga tttttgtaga ccacgaatct cagtcgccat
    14761 acgttcgatt gaagtcgcaa tgctggcaag aaccgcaaag tactcagcgt gaaggtcacg
    14821 aggaaggact tgtgtagaga tttcttgggc acggatgcca agtttatcgc agacatactc
    14881 ctctacaaat ggtgggatat tggcaaagtt cccaaccgca ccagaaatct taccagcttc
    14941 tacaccagca gccgcatgct cgaagcgctc gatattgcgt ttcatttcgc tgtaccaagt
    15001 tgctaattta agaccaaagg ttgtcggctc agcgtgcaca ccatgagtac gccccatcat
    15061 gatggtgaac ttgtgctcct tggccttgtc agcgatgata ttagtgaagt tttcaaggtc
    15121 acgacggatg atgtcgttgg cctgcttgta gaggtaacca taagcagtat ccaccacgtc
    15181 agtagaagtt aacccatagt gaacccactt gcgctcttca ccaagagtct cagaaaccgc
    15241 acgcgtgaaa gccaccacat cgtggcgcgt ctcctgctca atttccaaaa tacggtcgat
    15301 gtcaaagtcc gccttcttgc gaatcaaagc cacatcttcc ttagggattt cccccaactc
    15361 agcccatgcc tcgtcagaga ggatttccac ctcaagccaa gcacggtatt tattttcttc
    15421 actccaaata ttcgccatct cagggcgaga gtaacggttg atcatgtgtt aatttttcct
    15481 ttcttcttaa gctgttggga ataagctatc taggtaaacc aagatttcta ctcaaactcc
    15541 tcttttccaa taaacacaga cgggtaatga tctagtgtat tcaaatccgt atccagcggt
    15601 acatcataga tagctaaata attttcgggg tattgtgcag ctagttcttc atatttagct
    15661 tgtaccttat cttggtcagc actggcatac aacacttcaa caactgctcc agtcttatcc
    15721 ttttcaataa atgtattaac gataatttgt atcatagact tgtcctaaaa atcaatccct
    15781 tccccaagct catccacact atctggttca ttactaatca aagtcacatg tcccatcttg
    15841 cggttgtgct tcgcttctat tttaccatac atgtggaggt gggcgcttga attttctgtg
    15901 acatattttt cagcggcctc aacatgctgg ccgagaacgt taagcatgac ggcaggcgca
    15961 tggagtttga tgactggtaa tggtgctccg agaacaccga gaatatgggt gtcaaactga
    16021 gagaaatcac aggcttcaat agaatagtgc ccagagttat gtggtcgtgg ggcgatttca
    16081 ttgacaataa cgtcatcatc agtcgcaaac atttccacac agagagttcc agacaagttg
    16141 agttgttctg cgattcgcac tgccatagct ttagccttgt ctactagact ttcagaaatg
    16201 cgggctggta cgatggtctt agacaggata ttgttgcggt ggatattttc ctgaactggg
    16261 aaaaacgtca cctccttgcc atttcctgac acgatgacag aaatctcaag gtcaaagttg
    16321 acaaattctt ccaagacgca gtctgctgag tctgctagcg cataggctgc ttccaagtct
    16381 gcttctgaac gaataacctt ttgtccatga ccatcgtagc caccagtcgc agtcttgagg
    16441 acatagtttt tcgacaagtc gatatctgcc aagtctaggc tagaagtcac gaccttgtag
    16501 ggtgccacag tgacttgagc cttgtttgac aaaaagtcct tttcaaaaat acgattttgc
    16561 gaaatgcgga gcagatctgt tccttgaggg agttgtccat ccttgataac ggcatccaaa
    16621 ccgtcagcgt cgacattttc aaactcataa gtgaggacat cgcaacggtc tgccaactga
    16681 cggagggcgt ccacatcgtt ataaggtgcc acaatgattt ccgccacgcg agaggccggg
    16741 caatccgccg caggatccag cgcgataacc ttgtggccca tgtagatagc agaaatggcc
    16801 atcatctgac ccagttgacc gccaccgata attccgattg ttttagatga gctcatttga
    16861 cgactcctct gcgatttttc cttgttcttc agcaaagttg gcaagtgcat ccgcaatgga
    16921 cttatcttct acagagagga gacggagggc aaagatagct gcgttagtcg ctccagcttc
    16981 accgatagcc atggtcgcaa caggcacccc acccggcatc tgaacgatag aatagagtga
    17041 atccactcca ctaagagcac gagacttgac tggcacacca atgattggaa gggttgtttt
    17101 ggcagctacc atgcctggca aatgcgctgc gccaccagca cctgcgatga tgatcttgat
    17161 gccacgacta cgggcttctt ctgcatgttt gaacatgagg tctggtgtac ggtgtgcgga
    17221 aacaactttc ttttcgtagg ctacaccgaa gcggtctagg acttctgctg ttttttgcat
    17281 ggttgcccag tcggattttg aacccatgat gatggaaatt actggtttca tttcttctcc
    17341 tttttcctct ttttcaacaa tcaccttagc ttgtgaggga cggcagcagc caccaaaggt
    17401 gtctcatgcc taaattggaa acccaaggtc ttccaatttc cctgaacgat tggattatca
    17461 tccaatcgtt ctttcacaac ggcggtgatt attctatatt tgctcgctaa cgctcgcaaa
    17521 ccatacgacc attaacgtat tttgtgaatt tttatttttc tttttgataa tggtcttagg
    17581 tgatggaggc ggaagcaaac cttcggtttc attcctaaac tttgagccta aggtctcaaa
    17641 gtttccccct gaccagaaca ttcactgttc tggtcttttc accacgacga ccattatcgt
    17701 gtttggcgac tgcgtcgcgt tattcttata tctttactta attgccttgc ttccgatatc
    17761 tgttcggtag aagagtcctt ctattttttg ttgggatagt tcttggtaga tgctggcttg
    17821 ggcttctttg acggtggcta ctgtggtaac cagcatataa actcgtccgc cgtttgagag
    17881 cagtgctctg ctattttccg caaacttagc ccctgcatag taggtgatga catcgccttc
    17941 tgtcttggct ggcaactcaa cgcccctttc atagtctagc gggtagccct tggatgcgac
    18001 aaccacaccc agagtcacac ccttgtccgt ccacatgata tttggctcct tgctatccag
    18061 gatatctgtg atattttgag caaagtcaga ggtcaaacga ggcaatataa tctgagtttc
    18121 aggatctcca aatcgagagt tgaactcgat gaccttcggc ccgtctgctg tcaagataag
    18181 ccctgcgtaa atgacaccta gataagggcg accttcttta atcatccctt ctagaactgg
    18241 cttgacaatg gtgtcaaccg ctgtatcaac tacactctgt ggtaagtgtg gaactggcgc
    18301 ataggcaccc ataccacccg tgttaggccc tttgtcgcca tcgtaggcac gtttgtggtc
    18361 ctgagccgtt ggcatgatgt agaacttatc accattgaca aaggcaaaga gtgaaaattc
    18421 ctctccttca aggaattcct caataaccac gcgcgcacct gagtcaccaa atttattgtc
    18481 caaaagcatc tcatgagcgg cttcgaccgc ttgctcaacc gtctcagcaa cgacgacacc
    18541 cttcccaagc gccaagccat ccgccttgac tacgataggc gcaccatgct tttcgatata
    18601 ggccttggct tcctcgaaat ctgaaaatgt gccataggct gctgtcgaaa caccatattt
    18661 gaccatgatt tccttggcaa aatccttgga ccactccagc tccgctgcag ccctagtcgg
    18721 accaaaggcc ttaagcccag cttggttaaa atcatccacg ataccagcag caagggcatc
    18781 atctggaccg ataaaggtcc aagcaacatc attggtcttt gcgaagtcaa tcaatttaga
    18841 atgttcggaa atagagatat ttaccaattc caaaccatcc agagtcatcc catcattccc
    18901 aggagctaca aagacttttt ccacgtcttt tgattcaagt aactttttag caatcgcatg
    18961 ctcacgacca ccagaaccga caacaagcag tttcattcct caacctcttt tgcgaattat
    19021 ttaccaacat tatatcaaaa aagttcgttt taatcttgtt tcagttagca ttttaagcca
    19081 aaaaaggaaa gaaactgttt tcttcccttt tatcttctta atgtctaaaa tgtctcacac
    19141 ctgtaaagac catagtcaag ccgtatttat tcgctgcttc gatggattct tggtcacgga
    19201 cagagccacc gggctggatg atggccttaa ttcctgcttt ggcgatttct tccacgttat
    19261 ccgaaaatgg gaagaaggca tctgaagcaa ggaccgcccc gttcagacga tctttggctt
    19321 ggtcaatggc aaggcgaaca gaagccacac ggttggtttg acctggacca acaccaagtg
    19381 tcatgtggtc gttggtcacg ataataccat ttgatttgac gtacttgata gccttccaag
    19441 cgaactcaag agcagtcgct tctgtctcag ttggctgacg tttggtcacc acttgccagt
    19501 cagctgggct ttccttgacc acgtcttgat tttgcacgag aagtccaccg actacacctg
    19561 tgtattctgc ttccacttcg ctagcctctt gagcattaaa tggcaaggca aggatacgca
    19621 agtttttctt tttattgatc aaaatagcta gcgcttcatc cgtatagctt ggggcaatga
    19681 tgatttcgag gaaaacgccg tgcatcttct cagctgtcgc agcatccacc tcacggttga
    19741 ggacgacaat cccaccaaag atagatactg ggtcagactc ataagcgtag tcccaagcag
    19801 tctcgatgtc atcagcttga ccaattccac atggattcat gtgtttgaga gccacaacgg
    19861 ttggactatc tttgaagtca cggatgatac ggatagcagc atctgcatca cggatattat
    19921 taaatgacaa ttctttcccg ttgagctgtt tggctgaagc aatagagtaa tctgtaggca
    19981 aagctttctg gtaaaagtcc gcgtcttgtt gaggattctc accgtaacgc attggttgct
    20041 tgaggtcata agtcaaagtg agtttttcag gcttgctttc acccacttga gctgtgaagt
    20101 attctgcaat caaggcgtca taagccgctg tgtgacgaaa tactttggct gctaaacgtt
    20161 ggcgagtttc ataagaggtt tcgccgtttg ctgccaattc gtccaaaacc acagcgtagt
    20221 cagcaggatc taccacaact gtaacactgg catgattttt cgctgctgaa cgaagcatag
    20281 atggcccacc aatatcgata ttttcaactg catcagcata agtcacatct ggtttaagga
    20341 tagtttcctt aaatgggtaa aggttgacca ccacaaggtc aatgagctca atcttgttgt
    20401 ccttagccgc ttccaagtgg ctatccaagt cacgacgagc gagaagccct ccgtggatat
    20461 ttgggtggag ggtcttcaca cgaccgtcca tcatttctgg gaaaccagtc acatcatcga
    20521 tagcaatggt atccacccca gcattatcaa gggcaacctt agttccacct gttgagataa
    20581 tctcccaacc aagttttttg agttcttggg caaattcaac aatgcccgct ttgtctgaga
    20641 cgctgattaa gacgcgttta gtcattatat tctccttttt aatcattagt taaacaccaa
    20701 ttaaatgcag taacagtaaa acaagataag caaaaccaag gctaagcata cctaagatat
    20761 tgatccattt tctagtctgt gatttgaaca ctcttataaa aatttgataa atcagtaagc
    20821 ctacacagac acctagcgta tttaaagtca aatccgttat atctgttata cctattgcta
    20881 aaatatactg taagcactca aacaataaac taatcaagaa acctgtcccg actattctta
    20941 aactagataa attagttttt atcaaaggga aacaaacacc taatggaata aaggaaatca
    21001 gattaaataa catttcagca aaaacaattt ttccatcgac tattagtggt tctgaaaatg
    21061 gaatccaatt gatatacctt ggagctaaga aaaatgctat aaattcagga tttgtttcaa
    21121 acttaaataa gattccccaa gttaataaca tcagatagac ataaaataca tatcgagttg
    21181 tttttttaga ttctaacatt acaaatacct ccgtttgaag ccgtcttcaa caaacactga
    21241 ctccaattta aaatcaaaga tatcatatga atcatcaaaa agtcaatctg taaatagagc
    21301 cttcactact tccggataca acctgtactc tgcttcatgg atgcgagctt caaatctgtc
    21361 aatggtatca tcagctagtc gtggcacacg aacctgtttg atgacctggc ctgtatccac
    21421 acccgaatcc acccagtgaa tggtcacacc agactgaccc acgccagcat tccaagcatc
    21481 ctcaatccca tgagctcctg gaaattctgg caagtaggct ggatgaatgt tgacaatccg
    21541 accttcataa gccgacaata aggttggtcc aacgattttc atgtagcctg ctaggcaaac
    21601 caagtcaatc tggtgttctt ccaagagttc gacaagggct gcttcgtagt ctgtcttgct
    21661 ctcaaactcc ttgagttcaa aagcatagga cagaacgccg agctgctttg cacgctcaag
    21721 cacataggca tcacgatggt ctgaaaagac aaactccact ggaaattctt cggcaatcac
    21781 ctgaaaattt gagccattac cagaggcaaa aaccgctatt tttttcattt gataatgaca
    21841 ctttcgtttt ctttcttgac gatgcgacca atttcataga ctgcttcatc caacaattct
    21901 tttacacgct ctacattttc agggctgacc gccaacataa gtcccacacc catattgaag
    21961 atttcaaaca tttcttcgtg tttaatctga ccatattttt caagggcttt gaaaattgga
    22021 agcactggaa ctttgctttc atcaatttca gcagctaggt catctgcaaa catacgaggg
    22081 acattttcga taaagccacc acctgtgatg tgggcaatgc cgttgaccaa ctcttctttg
    22141 atgagcggca agacagcctt gacatagata cgagtcggct caagtagaac ttccttaagt
    22201 ttcttgcctt ccaattctgg taggacttcc tcacctgtgt aatccgcaaa gacacgacga
    22261 accaaagagt aaccatttga gtgaatccca cttgaagcaa gtccgagaag aacatctccc
    22321 tctaccacct ttgaaccgtc aatgatttga gatttttcag ccacaccgac cgcaaaacca
    22381 gccaagtcat agtcgtcttc gccgtacatg cccggcattt cagccgtttc cccaccgatg
    22441 agggcagcac cagcctgcac acaaccttct gccacaccag caaccacttg ttctagctta
    22501 gctggttcat tcttccctgt cgctacgtag tcgagaaaat agaggggttc cgcacctgca
    22561 gcaatgatgt cgttgacaca catggccaca cagtcctgcc cgatggtatc gtgcttgtcg
    22621 tacttgatag ccaacatgag cttggttccg acaccgtcag tccctgaaat caagacgggt
    22681 tctttaaccc cagtcttgga aaggtcaaac ataccaccaa agccaccaag agctcccatg
    22741 acacctgcac gctccgtacg ggccacgtgc tttttaatcc gttcaacaac ttcataaccc
    22801 gcttcaacat ccacacccga ctgggcatat gcatttttat ttgtcatttg ttttttcctt
    22861 ttctttaatg gagaatctgt cgcctacttg taaaaactgg tcttttcttc caaacttcta
    22921 cgatagtctt cttcgtagtc atagagaggc gttgggtagt caccgtcaaa gtaagcgaca
    22981 cagagaccac cgttcggcgc atctgtttcg ataccaatcg actcaatcaa gccatcaatt
    23041 gaaagataag tcagactgtc cgcaccaatg atttggcgag tttcttcgac cgtatgattg
    23101 gctgcaatca gctcctgacg ggtctggata tcaatcccgt agaaacatgg atacgctagt
    23161 gcaggacttc caatggcaac gtgaacctca gtcgcacccg cttctttcaa gagctgaacg
    23221 atacgacgag aggttgttcc acgtacaatg gaatcatcca ccatgaccac acgtttgcct
    23281 ttgacaacac ccgaaacagc agacagtttc atccgcactc cttgctcccg caattcttga
    23341 gtcggttgga taaaagttcg ctgggtgtat tggtttttga tcagacccat ttcatttggt
    23401 aagcctgatt cttccgcaaa tcccatagcc gcgcttaggg aagaattggg cacaccaact
    23461 acaatatctg cctcatgctt aaattctcgc gccaattgcg ctcccattct cttacgtgcc
    23521 gtatggacat tgacaccgtg gatattagaa tcagggcgag caaagtagat atactccata
    23581 gaacaaatcg ccaactgagt atcatctgta tagctgtcat actgaatgcc ctcgtcatca
    23641 atgatcacaa tctcacctgg cttcaaatca cgaatccact cggcaccaat gacctcaaaa
    23701 gcacaggttt cagaggaaac aaccaccgct ccgttggcca ttttcccgat agaaagcgga
    23761 cgaaagccat tagggtcaag agccgcaatc aacttgtcct caaacagcaa gatataggca
    23821 aaaccacctt tgacaaggct gagcgcttcc ttgattttgc ccatcaggct aggattatga
    23881 ctacgacgaa tgaggtgagc caagatttca gagtccgaag tcgcgctgaa aattgctcct
    23941 ctttgttcca gttctttctt gagagaggct gcattggtca gatttccatt atgagccaag
    24001 ccaaactgca tatcgtgaaa acggaagagg aagggctgga tgttatcaac agaagcttcg
    24061 ccagcagtcg cataacgcac atgcccaatc gcaccagctc ctgtcaattt atccaaattg
    24121 gctggatttc tgaaaacttc tgataaaagc cccatgtcac gatggcgctt cagttgtcct
    24181 tgatcattgg agaggattcc tgccccctcc tgaccacggt gttgaagact gtggagtcca
    24241 aaataggtca acttagcagc atctggatgt ccccaaatac cgaaaacacc acattcttca
    24301 ttaagagatt ttacttcgta tgtcattttt tatacctaat tttcatttgt aatcatcaag
    24361 agctagattt acatgacttt tacattactg atactatcta ttagaaaatc tgtaagtctt
    24421 attttccagt gaaatgttta accgctgatg cgaacaggtg ttggtcttta ttgcctggga
    24481 tattttggaa aagaccatcc tcataacgtt ctgagtggcc catcttaccg atgatttgac
    24541 cattcttgct ggtaattcct tcgatggcat ggacagaacc attcggattg tacttagaat
    24601 ccatacttgg tttaccgtta aagtcaacgt attggctgaa aatttgtcca ttgtcacgga
    24661 gctctgcaaa ttcctcagcc gtcacgacaa acttcccttc accgtgcgaa acaggaatag
    24721 cgtggatatc gcccacttgc acaccagcca accatggtga gttggtattg gcaatgcgag
    24781 tttccaccat cttggccacg tgttggttgg catcattgta gaagagggtt ggactagtac
    24841 tgttagcatc ttcaaagttt ccgtatggta ggagacccga tttgactaag gcttggaatc
    24901 cattacaaat accgataatc aagccaccac gggcgataaa gctatcaata gccacacgca
    24961 ctttttcatt aagcaggata ttgacgataa acttagctga accatctggt tcatccgcag
    25021 ccgagaatcc accggcaaag aagagaatat tagtcttgtc gatattgtca accatagttt
    25081 caactgactt gacaatagct tcttcattca aggtcacgaa tggcaccaaa ttgacctctg
    25141 caccttcttt ttcgaaggcc ttagctgaat catattctga gttggttcct ggaaagactg
    25201 ggatgtaaac cacaggtttt tcaacctttt ctttggcttt aatcacaaca tctgatgcca
    25261 cagctggtac ttcttctagt tctttcgctt gggtaaattc tgttgggtaa acttcttcca
    25321 atgtcccttg aaatgcactg tcaagcttgt gtccatctag cttcacaccg ttgacagtca
    25381 gtgtaaagtc tgctttcgtt tgtccaatct tctctactcc agcaatttct tcaggagatg
    25441 tgaagacaaa gccgcctaat tgagttgtca aagctgtttt aagttcaggc aaggtcacct
    25501 ctgcaccaat atagtttcca aaggtagcaa gagccaaact ttcaactaca ccaccgtatt
    25561 tgacagctga tgcagacgtc actttatggt cagcttggct tgcttcaaac tgagcaaaat
    25621 ttttcttaat caagtcaaaa tcaatctctg cagagagggc ttgacctggg atgtagtaga
    25681 tattttcccc aacagcttta aattctggag agagcacctt acggctatct gccgtcgtca
    25741 ccccaaaggc aaccaaggtt ggcggaacgg tcaattcttc aaaggtacca gacatggagt
    25801 ccttaccacc gatagatggc aagccaagct gaatttgtgc ttcaatagaa cctagaagag
    25861 cagctactgg ctgaccgaaa cgctctgctt gcttgtccat ccgctcgaaa tattcttggt
    25921 aagagaaacg agccttagac cagttggcac cagcagccac caaacgagca gttgcttcga
    25981 taaccgcata agcagcaccg tggtatggag accattcagc tacatatggg ttgaaacctt
    26041 gagcaatgac cgacgcagta tgagtcacac cgtgttgaac tggcaatttc tgcacagatg
    26101 cctcagttgg tgtgagttgg taacgaccac caagtgggtg attaaccgtt gagcgtccaa
    26161 cagagcagtc aaagatagtc tgtaatcctt tttgacttgc atggttgagg tcagatagaa
    26221 ccgtaagggt atctgattcc agtgtttcag cagatgtttg acgctcttct gggagtttga
    26281 catccttgtc cacaactttg gcatcgacaa ccacgcgcac accattggtg tcaaggaaac
    26341 gacgctccaa gtcaacgatt gtctcaccat tccagtgcat gacaagattt ggtttttcag
    26401 ttactgtcgc caccacaaca gcatcaatat tttctttgtt acattcggca acgaaggtat
    26461 ccacatcttc aggacgaacc acgaccgcca tccgttcttg tgattcagag atggcaattt
    26521 ctgtaccatt caagccctgg tatttaagag gcaccttgtt gaggtcgatt tcaagaccgt
    26581 ctgccaattc accgatagcc acacagacgc cgcctgcccc aaagtcattg gacttcttga
    26641 tcagacgagt gacattgcca ttacggaaga ggcgctgaat cttgcgttct tcgatggcat
    26701 ttcctttttg aacctcagca ccagcagtct ctacagactc aactgtttga accttagaag
    26761 agcccgtcgc accaccgaca ccatcacgac ctgttttgcc tccgagaagg atgatcacat
    26821 cacctgcttc aggtttttca cggacaacat tgcccttggg agccgcacca acaacggcac
    26881 caagttccat acgtttagct acaaagcctg ggtggaagta ttcacgaacg taggttgtgg
    26941 caagcccaat ctggttacca tatgaagaat aaccatgagc tgctgtttta gaaatgactt
    27001 gttgtggcaa tttcccagca cgagtttccg aaatcggtgc tgtaatatca ccagcacctg
    27061 aaatacgcat ggcttggtaa acataggaac ggcctgacaa cggatcacga atagctccac
    27121 cgatacaggt agccgctcca ccaaatggct caatttctgt tggatggttg tgggtttcat
    27181 ttttaaacat gaggagccaa ggttccttga caccatcaac atccacttca atttcaactg
    27241 agcaggcatt gatttcgtca gagacttcca tatcatccaa tcgtccgtta gcacgctcat
    27301 aacgaccgaa aatagtcgcc atatccatca aggtttgtgg tttttcagac cgacctaact
    27361 cctcgcgcat ggcaatatac ttgtcatagg ttgactgcaa ttgcttttga aatttagaag
    27421 ctgaaaagtc gatgtgtttc aactctgtct caaaagtcgt atgacggcag tggtcagacc
    27481 agtaagtgtc caaaaccttg agttcagtct cagttggcac gcgcccgatt gacttaaagt
    27541 agtcttggat aaagagcaaa tcatccactt ccatggccat cccttgctcg gccttgtagc
    27601 gagcaaagtc ttctgctgta tagctttcaa agaaagtcaa ttttggaatg gtcttgtctg
    27661 actctgaaaa ctcctgcttg gcaatccctg tcgtgatatc cttgaaacga gaatcaactg
    27721 gattgagcag gtagtttttg acagcttcca actcagtcgc atcaatatct ttattcacca
    27781 agtaaagttg ggctgtgttg actgtcacgt cactcgaact tcccaacaaa agcaaggctt
    27841 cctgtgacga agctgcacgc tggtcaaact gccctggcag actttcaatg gcaaagaaag
    27901 catagttagc aagatccgcc tgcacagata cttcatctaa aacatggtcg gttccctgct
    27961 cagagaaaat gtgcttctct gcaggtgcaa acaagtcctc agccaagtca aatacatcat
    28021 atacttgcac aatacgaata cttttcaagc ttgacagtcc caagttgtgc tggaactctc
    28081 taaccaaact ctctgacttg acctgaaaat cagccttttt ttcaacaaaa atacgtttat
    28141 ccatcaattc ttattccttt atttcagctc ttgcaatatt cccaaacagc cttgaggttg
    28201 ttattttaaa ccctgcaact tttcccagac aatttcgtaa acatctgtta gttcacctag
    28261 ttctctacag agtgaaaagg tctgggggac cttttcagcc tgagtccttt tagttgagag
    28321 acgaaggttt tccgttgcaa acagattatt tcaattcctg caacttttcc caaacaatct
    28381 cataaacgtc ggttagttct cccaatcctc tacggaaaac atccttatcc atgtggttgc
    28441 catcagcgtc ccacaagcgg cagttatctg gtgaaaattc gtctgccaag ataatcttgc
    28501 catccttgtc aaaaccgaac tctagcttaa agtcaatcaa tttaagccca atctcagcaa
    28561 accagacttt caatagttca ttgatacgac gcgtttcttc cttcaagtag gcaatctgct
    28621 ggtcacccgc aatctgtagg aatttcacat gctcatcatt gataaatgga tcatccaaat
    28681 catcattttt gtagtaaaat tcgacaatcg gagtctccaa ggcgattccc tcatccacac
    28741 caaaacgttt tgaaaaagaa ccagcagtat agttgcggag cacgacttcc aaaggaataa
    28801 tcttaacctt tttattgagt tgttccgtgt ctgaaagttt ctccacaaag tgagtcgcca
    28861 caccagccgc atttaatttc tcaaaaataa aagatgagat ctgattattc aagactccct
    28921 tacctgcaat ctgctccttc ttgacaccgt tgaaagcagt cgcctggtcc ttgtaagttg
    28981 aaataataag attttcatcc tcagttgtat agatatcttt agcttttccc gaatagatca
    29041 attgttttga cattttaaag ttcgcctttc gtattacttg agcacatttt accacaaaaa
    29101 accaaaaaac acaagaattt aaccgaataa atagtagatg tttttcaaaa attgtaaaga
    29161 aaaaactgca agaagaatct ttctcacagt ttaaaaatta tttaactcta aaaacacgaa
    29221 cattactctt tgttcaaaaa ttgatccaaa taataacgta gataactttt cttgcccgta
    29281 atcatctgca agcggccttc caccccgtac ctaagttttt cagcctgctc cgaagttaga
    29341 ttagtctccg cctctatttt aaagaaattc cctttctcag tcttagtagc tgtcgcatca
    29401 atacttgtaa tagttgaatc taggaaaagt tgattcccgg catcatgagt cgtagtatag
    29461 cgaacagaat caccgacctt gattcttgct acatcttttg aacttagata ggctgtgagt
    29521 ttggctttcc cttctctttc caaagatgga taaagttggg ctagtagggc accttctgca
    29581 accatgctag aatcactggt ctcaggatta agatgaagca ccccatcctc actcgccgta
    29641 attttcccct tgtctaaaag atttccctgt accttcttac ctgactctgc ctccaagatt
    29701 ttctgggcta gaagggtcaa ttcctgacca acctttgcca aatgttggga tttaagggat
    29761 tccaattgac tgcttaaccc tgacgcatag gcttgctggg tacctgaacc tgcatactgg
    29821 acacggtaag tagcaagact agattctaac tgagaaatct gtgcttcaac ctgtgcaact
    29881 gcctgaacct tagtttgggg attttcctcg ccctgagact tgtaggactg gtaaagagag
    29941 taggctagat tctgactggc caaggaagca cctgtttcca tagctgactt agctgtctgg
    30001 taatcgcgaa ttttagcctc tgtttgactg atgaggttgc cgatttcggc ttgggtttgg
    30061 ctagctgctg cattctggga cgcgatggtc tcattttgtt gcgatgtact agccctaaga
    30121 ctgcctgctt gactgatgta gtcgcgaaag gtggcttggt agccaaactt atcctcctct
    30181 ggaaagtggt tctccccttc ttgcaggctc ttttgcagat actctaattg ctttttttga
    30241 tcctttagca tgtccaactg actggcatag gactccgctt ggacaccctc tgccccttct
    30301 tggtattgaa ccaaaagatc ccccttctta accagcttat tttcttccaa atgattgaca
    30361 agaatacgat tgttgctagt tgactggata tttgcaagga tacgactggg ttcgatagta
    30421 gctctagtgg acaaactcat ctccttctct gcaacagttg caaagccaag taaaaacacg
    30481 agcagaaggg ccatgggtac aatcacacta ctggaaaaat tatggtaacg acgattataa
    30541 aactccgcac tttctaaaaa ttctggtttc atcctctcct ctttctagct attgaccaaa
    30601 tgggcgtaaa agcctccctg tgcaagcaaa tcagcatgct ttccttcttc gacaatcttg
    30661 ccctgatcca agacaaccac cttctctgtc cgctcagcaa tagtcaagcg gtgagcaatg
    30721 aaaatcaagg tcttgtccaa agccatgaga ttatcgacaa tccgcttctc tgtcaaaata
    30781 tccaaactgc tagtcgcctc atccaaaatc aagaccggcg catctgtcaa gagagcacgc
    30841 gccaaagcga ttctctgacg ttgaccacct gaaatccctg ccccatccga agtcaattct
    30901 gtctgataat tcagtggcat gcgctcgata tcctctcgaa tctctgccaa ttcgaccgcc
    30961 cgtaagatat cttcctgtgt cgtcccctcc ttggctccca aaagaagatt ctccaaaatc
    31021 gttccgttaa agacataggg ctgttgaggc agatagttga tgtactggcg cagggctttt
    31081 ttatcaatct gattgagatt gacaccaccc agactaatct ccccttgact tgggtcgtaa
    31141 aaattaacca tcatcttggc caaagtcgtc ttacctgacc ctgaaatccc cacaaaagcc
    31201 accttagacc cttggggaac ggttaaattg atatccgaca agacgtctcg accatagcca
    31261 tacttgtaat gaacctgctt gaaggtcata tctcccttca tcaagctcaa atcctcaact
    31321 gttttcttct cctcaaactc agaagctact agatacactt catttagacg gttattggca
    31381 acctgcgctg tctgaagctt ggtttgcaga ttgatgatat tttccaaagg attggtaaag
    31441 taaaccagca aggtattata ggtaatcaac tgccccaaac tcatcttgcc atccatgacc
    31501 agaacagccc ccatccagag aatgccgaca ttaagcaaga gatgggcaac ctttttcaga
    31561 gccttttgct gactctctgc tcgactatag gtaaaggatt tcttcagata atccacaaat
    31621 tccttgtcaa ttttttggta acgctgactt tcactggtca aggacttgat agtctcaata
    31681 ccgttgatgt cctcaatgat agaagaagac agaaccgcat tggcttccat ggtatcccga
    31741 ttcatctttt caaacggctt cataaaggca aagataatca ctgtgtagat aggaagcgcc
    31801 aataaagtca tgaaaaagag attggtattt tgtgaaaata gaacaaggga aataatgaca
    31861 accgttgaca catctaggaa aatcgaaagg atggtcgaag ccagcgcatc gatgatactg
    31921 ttagcatctg taaaacgaga cacgatctcc cctgtcctgc gtgtcgcaaa gaaggacata
    31981 gggaggtgaa aaacatgctt gatataggac aaaatcacgt caatcgacaa gcgttgcccc
    32041 aaaacaagca agagatactc ctgagcgtaa gacaagattt gctggaggat gtagacgatg
    32101 actagcccaa tagaaataat ccctagtgtc gaacgcatct gatctggcac ataggtatca
    32161 atgatagact gcagataata agaacccaca atgttaatcc cggttaccaa gagtgttgcc
    32221 aaaacgatat tggcaatcaa gccacgctgc ttcactaata tagggataaa agagagcaga
    32281 ccattttttt gttccttata aggcttatag tctggactag gtgccataaa aagagtcact
    32341 cctgtccatt cttcctcaaa acgctcacgt ggcagtttag tcaacttcac cccgggatct
    32401 ggatcggcaa tatgaatgct atccttatcc tgcccagtca ccacatagta gtggagcaat
    32461 ttcccttcct taagcacatg ggcaacaaaa ggaaaagtca aatccggcaa gtcaaaaagc
    32521 gtcatatccg ccttaatggc tcgcgtctca aaaccaatct cctctgccac cttgaccaag
    32581 cccaaagccg tcgtcccatc catggtcgtc ttagccaatt ctcgcaagtg agccaaaaaa
    32641 taataactac catagtagcc aaaaaccatg gctaatgaag ctacaccgca gtccatctga
    32701 tccacttgcg gacgatagtg acgtttccca aatttcatat tcatctcctt ttccctaata
    32761 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggctgctcaa aacactgttt
    32821 tgaggttgta gataggactg acgaagtcag tcacatatat acggcaaggc gacgttgacg
    32881 tggtttgaat ttgattttcg aagagtataa actcatctga taacaactat cttaccccaa
    32941 tcactaaaca aaaactggac ttccttccca aatgagccta tctccctccc aactgcactt
    33001 tttggataaa aaaataggca gaacaaacgt tctacctaga aaatataaga attacaagtt
    33061 aacaaaaccg aaatgatttc atatcattat taagtaaaga aaaaaatttt agtatttcta
    33121 aaaactattt ataatagaca ttatagcatt aaataaaaat ggtacagaaa acactactgt
    33181 caatcttaaa tttttaaatc tcgcataatt tgttatccca attagtaata ctgtcaatac
    33241 gctgaaatag gcaaacttta tatccgatgg attaaataaa taacaaagta aaatgctaaa
    33301 acttaaggtt atatttttag ataaaagaat atctccaaag ttcctcttat tcttatcaaa
    33361 aaataatgta atcagaaaga gagaaaatcc atattcaata agagttgcta taaatgtgaa
    33421 aacaacagaa atcactgtca atattgtttc tattttaatt gtaaaaagat tagatagttc
    33481 agataattta tcaatttgtt catctaaaat tcccgacttc atcagtaaat caataaacaa
    33541 atataaaaga aaaagataaa taatcagatt cattaatttg tataaactat tatttgtttg
    33601 aaatttcata aacccgtcct tcctctatta aaatcctttg agatttgcta atcaattctt
    33661 gattcaataa attatgagat acatatataa tagtagagct ttctttcatg gaaattaagc
    33721 gtttagcaat catatcaata cttcttgcat ccactgttga taaagtctca tcaataaaaa
    33781 tataatccca atttttagca aaaattaagg ataagcctaa tttgaatttt gttccagtag
    33841 atgctgtcat atagttatct ccgattttat tatcaaaaaa agtattaatt tgttctttat
    33901 cctcaaatga tagatggatt tgaaaagaat cacacaacaa ctgcaaattt tcttctatag
    33961 taaatggaac aaccccaagc tgattggtat caaggtatag tacatctttg gagacacaat
    34021 tctttaaacc actatcaaaa gtctctagcc cagctaaaag ttgtagaagg gtgctctttc
    34081 ctgaaccatt ctctccttca actctgtaaa ttcccttatc aatctctagt gatatatttt
    34141 tcaatataca tttatcataa cttttagatt cattttcaat tttcataatt taattccctc
    34201 tatcaacgct gctaaaatta ataaaagata agaaatgata taccatttta aattactttt
    34261 tatataaata agtatatttt taattcccct atccttcaat aatcggtata aaagatactg
    34321 actcatacct tgataccaaa taaaattcgg tatttcaata agagcatgag gtaatattcc
    34381 ttttattgta gctactattc caatcatctg accagatata cccaattgta ttcctaaaga
    34441 tagcaaatca aaaagttgca ataagggcga aatcggaaaa cagaatagat atagcaaaaa
    34501 atttgtagaa tttgcctgta aaactgtcaa tgtaaattgt aattccagtt tcggaggtat
    34561 agtagcaaaa gtctcatttt ttaatataaa gcttaaaagt aaacctagta aaaaacagac
    34621 tatacaaaat aacacatagt aaatcagaaa accacttttt ctcatctaat gccccctact
    34681 aaaattacaa atattatcag aaaacaatat aaaaccagaa aactccatct caataaacta
    34741 actgtacctt taattaaaaa tagagctttc ttataataga cataggctat aaaataattg
    34801 aatggaatca ataacaaatt caacaaaata ctttttatat cattactata acttgtcacc
    34861 ggaatcaaac ataacaacaa tgaaaattgt aagaaagaga ttaaatgcgt caacatcatt
    34921 agttgtgcat tcttaaaaaa gaaattcatt ttagaatgat taagagcaga taattgaagt
    34981 aaagctagat ctaccccaat tgaggattta tgattcccta ttattgcctc cattaatgta
    35041 atatatattg aggtataaag aaataatatt ggtatttttg tgtcatcaat tgataacatc
    35101 gtcatcatat accaaaatag ataggaaaga agaatactaa tcaaaataaa agaaaaagtt
    35161 aaccctttat ttaaccaaca aaaacgaagc aatataaata gactgctacg aaatcttttt
    35221 tgactcattc gactgctttt aaaatagaaa ttactcgcat gattatctaa tatccccata
    35281 actaaaataa aataattgag tagtatgaca taaattacaa cttgtccttg ttctatagac
    35341 aatagtccta tagataaaaa taagaacaat ttacttataa ttgaaaacaa actaggtaga
    35401 attaaagaaa taatttgaat agctatcaaa caaagagtaa tggataaata aaaatatcca
    35461 ataatatcta gaaaatacaa aataaataaa taaataaatg aatgattgta aaatttggaa
    35521 agaataatat ttcttgacaa tggcaagaag atagagaaaa atatagtttt tccttatata
    35581 gaaagtattt atttttttac tttggatagg cagtttcata ttataacgat tcaaagtagc
    35641 gtaatctact accaaaaaaa gtaaaaataa tttcccttga aaaggaagat agcttttaaa
    35701 atagattgac aaacttatga taacaaaaaa caaaagggtt atcccaataa aattaagata
    35761 acctaaaata ctttcacatt cttttttaga aagtattttc atctagttct accatagagc
    35821 tgctttagca gcacctttct ttttcaatat ataaagaact gttgctgcaa tacccgaacc
    35881 aatagaacct actcctgtga ttgcacctac aattgaaatt actgctgtaa ctgtactata
    35941 agcactaatc aaattgacta cagtagcagc agcttttgtc gaaattccta atgtcccagc
    36001 caacatagga aaagaaacaa cacctaagct taaccaacta atgactgcta acattgctga
    36061 aacaataaga aatttattat gaaattccat tcttttagat ttcattttag tgtactcctt
    36121 ttgtatatta tgtatgtttt attgagagtt aattcgcaca tgttgtattc ctaactctct
    36181 tcaaatgttc gtctatattt tatactactt ttattaacat atctataata aataaattac
    36241 tactacattt tcctagatta tcaaattact tttatatcac taagactcaa taaaagataa
    36301 tgtctattta acttttatac gattactacc tcctttttag tttacacttc ctacatcata
    36361 aataaacata ctaaaccctc acaatctcca aataactctt ctatatcatt gaaaattgag
    36421 tttcatcctc tatactaatg taggaaacct attaaaacat tcctttaatc caatataaga
    36481 ataccttgtt ccattaatct ctacccgata ttatagatag aaccaaattc ctatacttaa
    36541 aaggacaaat aacgttccaa ccataataaa cctcctttct ttttgagaac gttttcttta
    36601 taggtttagt gtagcaaaaa catgaaaaaa acaacatgac ttagaagtca ggttgttggg
    36661 aaatctatct gtttttctgc taaaattctc tgaactaata cctgatcgtc tagcaattct
    36721 gctagagaaa tcgccttttc atagaaactt tctgcctcta aaatattctt gtctacaaat
    36781 aaagcatatt ttgcctttag caaaaataga tgaggtcggt aaaaaacatg tcttgtttta
    36841 gcaataattt tctcaaatgt ttgaatatat atcagactat cttctgtctg aatttggata
    36901 aataggctca gaagaacttt ttccatttga actaggctag ccttatcttc atattctgaa
    36961 catagcaata ctttttgagc taactcctca aaatgttctt tatcttctaa tcccatagca
    37021 caacaaaaga aatacaattc aataatcaac aaatcattta cagaaaaata tttctttttt
    37081 aataactgct ggaaatattc ttccactaac cctaaaccgt aggtcacatc tgaactacca
    37141 taaatatcaa aacgagcttg tgtcacatcc acaattaact gctcttcctc aggcaaattc
    37201 tcataatagt tttcatatat ttcctcaagt atagcttctt ttcgttcgat tcttccctta
    37261 tcagcgtagg tttgagaatg aatcagctca tctttgagtt ttaggaatcc ttttggaatc
    37321 tctataacct taacatccac aatattctgt aatgatactc caagtttatc cgcaatcaat
    37381 aataatttag gaagtgttgc taaagcttgc ccattttcaa tacgtgctag ctgacgaatc
    37441 gtcaactctg attcatcacc acaaatatct atctgagttt ttccacaaga tcgcctaata
    37501 gttttgattt tataaccaat ttcacgtttc aactcatcca tagtaatact ccttaagttg
    37561 attacaaaga tttctttttc ttcctaattc ttttgtcaat catatataaa acgataagcg
    37621 aaaacagcgg tagaacaata taactctttt cactcattat cagctgaaat cccagggttg
    37681 ctagtatctt aaagatgaaa atattcatca aaaatagaaa aacaaatact aaaaaatatt
    37741 ttaaaacctt cttcatttct tttcttcaac tttcctaatt tctacaccta ttttatcgaa
    37801 aatatatata aaactccaaa taaacacttc gactgcactt tttttggcaa aaaatagaca
    37861 gaacaaacat cctacctact aaaaatatga tatgaaagga aaatgatttt ttactgacac
    37921 cctaggcaag cttgggacaa ataaatcatt gatagcaaca tttacgacat cctatttaaa
    37981 gttccttcaa tttctaatgt ccccgctatt tctaagccac ctctggtatg atctattcct
    38041 agtcagaata gataacaccg ttctaaatta cgattcatag ttactccttt tttgactcgt
    38101 tactataaga ctcctattta catgcgcaaa ataattttga ttcagattca tcatttatag
    38161 ttttgattat tttttaacag atttttctgt tttcttctcc gaagacttta aaaatttttt
    38221 tctaattaaa tcatccatat aaggaccaaa tataccaact actaaaccaa taataaaact
    38281 tttaaaatcc ataattacca ccaacatgtc gctgcatagg ccacacctcc aagtatagct
    38341 cctcccacag caccagttgc tgcaccttgc catgttcttg ttttaattcc tagctgaaga
    38401 cctcgtgctg ctcctcctcc aacacctgct ttggcaaaat ctccccaatt gcatccgcca
    38461 ccttcaacgc aagcaagcat ctcagtatcc ataatttcaa attgtgacat cgtttttgta
    38521 ttcataacga atacctcttt tttattttta atatttgtct tgttacaaac ttgacaagtt
    38581 tagtataaca gtatctatta atttttttca tccaaatctt gaattggcat cgaaacgtct
    38641 tgaattagct tttttgtttc aaaatcatct ctatttttaa aaaagatgtt ttctaatcac
    38701 ttttttacta ttagacttcc tgcaaaacta gaatcctagt tcatgattga taataccagc
    38761 aatcaaattc attcgtaatc cgaagcgttt acgatgattt cgataggttg ttgaaaacat
    38821 tttaaacgtt tttattttgg caaagatatt ctcaaccttg cttctctcct tagatagcgc
    38881 atgattacag gctttatctt caactgttag cggcttgagt ttgctggatt tacgtggagt
    38941 ttgtgcttga ggatatatct tcatgagccc ttgataacca ctgtcagcca agatttttcc
    39001 agcttgtccg atatttctca tttctaaaaa ccatctactt ccgttgactt ggaactccga
    39061 ttgctatttt ccttgaatga ttttaaccac atctcctacg ttttggagtt ggtcaatttc
    39121 ttcatcgctg atttcgatac taaattcatc ttccagagtc aagataaact ccatcaagtc
    39181 aacagaatcc gcatccaaat cgtctttcag actcaaggat tctgtcacga caaagtcctc
    39241 tccctgtcgc tcttggataa tggtcacaat acggtcaaaa atttcttttt ctgtcatctc
    39301 ttttattctc ctgaaaattc acgcgcagtc tgggcaacta cgtctgtttc tagcatggta
    39361 cgaatctggc gaatcgtact ataaacagcc ttggcatcgc ttgagccatg agtcttgaca
    39421 acaggtgcct taacaccaaa caagaccgct ccaccaacat ctgaataatt gagctgtttt
    39481 ttcaaaccac tgaggctgtc cttgagaagg agggcaccta gtttcgctcg aagaccacca
    39541 cctgtaatag ctgtcttgag caagcccatg attcccatag ctgtcccttc gatggatttg
    39601 agcacagcgt ttcccgtgaa accatctgcc acaacaacat ctgcaacgcc attcatcaaa
    39661 tcacgcgctt ccacgtttcc gataaagttc aaactttcat cagccgccag taattcataa
    39721 gtttccttac gaagcgggtc gcccttgcta ctctctgttc cgttgttgag caaaccaaca
    39781 cgtggttgcg caatgccacg aacattcttg gcatagaaag aacctaggac agcgtattga
    39841 tggaggtgct gggctgtatt ttctgcatta gcaccgaggt caagcatgtc aaaacctttc
    39901 ccatctatag tcggcaatgt tgacataagt ccaggacggt cgatattctt gatacgaccc
    39961 acgatgaaga atcctgctgc caacaaggca cctgtattcc cagccgaaag gacagcgtct
    40021 gcttcaccat ctttgacagc cttggctgcc aataccatac tggcattttt cttattccta
    40081 atagctctca taggttcatc atccgaatca atcttctcat ccgtatggat aatgctgacg
    40141 cgctctgtcg ctgtcagata ttgcttgatt ttagcttcat ctccgtaaag ttgaacctcg
    40201 atatctgaaa agtcagatag ggcttgattg acaccctcaa caatggcctg aggtgcgtaa
    40261 tcgcccccca tggcatctac tgcgattttt ttcatttctt ttcctctttt agtaattgtc
    40321 cccagtctgc tagggaatca ataaatttct ttgattttag gtgaatccca acgtactctt
    40381 catataattg atccataaat tggcgtagct cttgcttgat tccaggcttg agcgaaatgg
    40441 tctccaaagt ctcaaaatca atagcttgaa attgattgag cagatagggg atattgggat
    40501 tgagatgaca acgtctctta tcctcatgat aatgctctgg acagaggcag gctccatatt
    40561 tgaaagaaaa gtcaaaagcc tgaccaaccc gatggcagaa gacacactca ttaaaattga
    40621 ggctgattcc aaatcgagtc aaattttgaa tttcaaaaat attggtcaaa acctgataat
    40681 ccaagcctgc ttccatcaac tccaaagtct tttgcaaaaa agcaaacaag ggagcatcct
    40741 gctgattgtc ctgcaaacta gcatctgcaa gagctgccac ataggtcgca taggccatga
    40801 caaagaggtc actattaatc ttgggaaaag tcatgacctc atgatagtct tcgatgtaac
    40861 tgagtccgtc atcattgatt cgcaagagaa atcgtgccag caccaagggc tgaataacag
    40921 gcgccagctt agactgacca gcgtgtttga caaaaaacat gcgtttgcca acctgctctg
    40981 taaaaatttt gacgagcttg tcatcctcac gaaaattgcg attgtaaagc accaagcctt
    41041 gactcgtgat agactgaatc atgcttctct catgtactcc tcaagtcgtt tcatggcttc
    41101 tttgatagtc tccatgctgg ctgcataaga taggcggacg tagccttccc cgtaacgtcc
    41161 aaaggctgca ccagggataa aggcaacggc cttcttctga gcaaaatcct tcagaaaagc
    41221 aaaggagtct tgattgtagc ccgctggaat tttagcaaaa atatagaagg caccgtctgg
    41281 tttgataatc tcaaaaccaa gagcagtcat tttttcgatg atatagtccc gacgttggat
    41341 atattccttc ttcatgggct ccgcatcgtt tttaccagcc gtcaaggctt ctaccgcagc
    41401 atgttgcgcc atggtatttg cggcagtgac caagtactgg tgactcttga ttaactgggc
    41461 tgtgaaggtc gcaggagcga aaatcagccc caaacgccaa cctgtcatgg catgcgattt
    41521 agacaaacca ttgataataa tagcctggtc tctcaacatc gttcctagag acacatgggc
    41581 ttcgcctgtg taggtcaatt ctgagtaaac ctcatcacag acaacaaaaa tttcgtactt
    41641 gcgtaaaaca gctgccaagg cctctaactg ctctcgactg taggtaattc ctgtcggatt
    41701 ggctggatag ttgagaataa ccgccttgag cttatcaccc tgctccaaaa tggccttctc
    41761 caacatctca ggagtcaaga caaaaccatt ttcagtcgta tcaatctcaa caatttctgc
    41821 cccaactaag ttaacaatcg gttcatagcc tggataagca ggagctggca aaagtacctt
    41881 gtctccctct tccaaaatag ccgtcaaagt cgcagataaa gcctctgtcg ctccgatagt
    41941 gaccaagatt tcattttcag gagcatagtc cagttggtac ttttccttaa caaaatcact
    42001 ggccgcctga cgtagagtca gcagaccact catccctgta tagtaggatt ggttctgatc
    42061 aatcgctcgc ttggccgcct ccttgacatg gtctggcgtt gtaaaatcag gttcccccaa
    42121 ggtcaaacgc aagaccccag gaatctccga aatagcctgg tcaaactgac gaatcaacga
    42181 aacttgaatt ttatctaact gtttattaaa gcgcttagtt aagtccatag atacctccta
    42241 ctttcaaaac gtatctctat tatactacaa aagccccccg accgcaaaaa tacattagag
    42301 aatagctttc cactttctat tttacttttc ctgtttatag gtctataatg gtaatagatt
    42361 ttatttggag gtttttatgt catttctatc aaaaaatgga gcaggtatct tggcctgcct
    42421 tctcatttct atcgtatctt ggtacttagg aggattcttc cctgtgattg gcgcgcccgt
    42481 ttttgccatt ttcataggca tgctcctaca tccctttctc tcgtcctata aacaactgga
    42541 tgctggtttg acctttagtt ccaagaagtt gctccaatat gccgttgtct tgcttggttt
    42601 tggtctcaat atctcgcagg tcttcgcagt tggccaatct tcactccctg tcatcctgtc
    42661 cactatctca atagctctga ttattgccta cctcttccag cgtttctttg cactggatac
    42721 aaaactggct accttggttg gagtaggttc ttctatctgt gggggttctg ccattgcagc
    42781 gacagcgccc gttattgatg ctaaggaaaa ggaagtagcc caagccattt ccgttatctt
    42841 tttcttcaat gtcttggctg cgctcatctt tccaaccctc ggcacctggc ttcatctatc
    42901 caatgaaggc ttcgccctct ttgcagggac tgcggtcaac gacacttcct ctgtaacggc
    42961 tgccgccagc gcttgggaca gtctttacca aagcaatacc ctcgagtctg caaccattgt
    43021 taaactcaca cgtactttgg ccattatccc tatcacgctc tttctatcct actggcaaag
    43081 tcgccaacaa gaaaacaagc aaagcctaca actgaaaaaa gtcttcccac tttttatcct
    43141 ttactttatc cttgcatcgc tcctaaccac ccttctgacc tctctcggtg tgtctagtag
    43201 tttctttacc cctctcaaac aactctctaa attcctcatt gtcatggcca tgagtgctat
    43261 cggtctcaaa accaatctgg tcgctatggt caaatccagt ggaaaatcca ttcttcttgg
    43321 agccatctgc tggattgcca tcatcctcac cactcttggt atgcagaccc ttatcggcat
    43381 tttctaatac tcttcgaaaa tctcttcaaa ccacgtcaac gtcgccttgc cgtatatatg
    43441 tt
//
LOCUS       DBEJZV010000019        41879 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.19, whole genome shotgun sequence.
ACCESSION   DBEJZV010000019 DBEJZV010000000
VERSION     DBEJZV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 41879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41879
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.19"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            117..614
                     /locus_tag="ACL3S0_001238"
     CDS             117..614
                     /locus_tag="ACL3S0_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGR1312147.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            614..2269
                     /gene="dnaX"
                     /locus_tag="ACL3S0_001239"
     CDS             614..2269
                     /gene="dnaX"
                     /locus_tag="ACL3S0_001239"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGR1312148.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYTPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKSEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQIEKEVEESLIPEGFEFLADKVKVEED"
     gene            2297..2491
                     /locus_tag="ACL3S0_001240"
     CDS             2297..2491
                     /locus_tag="ACL3S0_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGR1312149.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2641..3411
                     /gene="sufC"
                     /locus_tag="ACL3S0_001241"
     CDS             2641..3411
                     /gene="sufC"
                     /locus_tag="ACL3S0_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGR1312150.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3439..4701
                     /gene="sufD"
                     /locus_tag="ACL3S0_001242"
     CDS             3439..4701
                     /gene="sufD"
                     /locus_tag="ACL3S0_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGR1312151.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLLGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4712..5938
                     /locus_tag="ACL3S0_001243"
     CDS             4712..5938
                     /locus_tag="ACL3S0_001243"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGR1312152.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINACSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5925..6365
                     /gene="sufU"
                     /locus_tag="ACL3S0_001244"
     CDS             5925..6365
                     /gene="sufU"
                     /locus_tag="ACL3S0_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGR1312153.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDVVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6419..7831
                     /gene="sufB"
                     /locus_tag="ACL3S0_001245"
     CDS             6419..7831
                     /gene="sufB"
                     /locus_tag="ACL3S0_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGR1312154.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8062..9303)
                     /gene="pbp3"
                     /locus_tag="ACL3S0_001246"
     CDS             complement(8062..9303)
                     /gene="pbp3"
                     /locus_tag="ACL3S0_001246"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGR1312155.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9406..10515
                     /gene="cozE"
                     /locus_tag="ACL3S0_001247"
     CDS             9406..10515
                     /gene="cozE"
                     /locus_tag="ACL3S0_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGR1312156.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLIWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11161..11508
                     /gene="ssrA"
                     /locus_tag="ACL3S0_001248"
     tmRNA           11161..11508
                     /gene="ssrA"
                     /locus_tag="ACL3S0_001248"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11681..11768)
                     /locus_tag="ACL3S0_001249"
     tRNA            complement(11681..11768)
                     /locus_tag="ACL3S0_001249"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11732..11734),aa:Ser,seq:gga)
     gene            11931..12671
                     /locus_tag="ACL3S0_001250"
     CDS             11931..12671
                     /locus_tag="ACL3S0_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR1312157.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12668..13579
                     /gene="pfkB"
                     /locus_tag="ACL3S0_001251"
     CDS             12668..13579
                     /gene="pfkB"
                     /locus_tag="ACL3S0_001251"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGR1312158.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSDGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13576..15528
                     /locus_tag="ACL3S0_001252"
     CDS             13576..15528
                     /locus_tag="ACL3S0_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR1312159.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15665..17917
                     /locus_tag="ACL3S0_001253"
     CDS             15665..17917
                     /locus_tag="ACL3S0_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGR1312160.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(17962..18390)
                     /locus_tag="ACL3S0_001254"
     CDS             complement(17962..18390)
                     /locus_tag="ACL3S0_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGR1312161.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            18528..19670
                     /locus_tag="ACL3S0_001255"
     CDS             18528..19670
                     /locus_tag="ACL3S0_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR1312162.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHSLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19679..20893
                     /gene="thiI"
                     /locus_tag="ACL3S0_001256"
     CDS             19679..20893
                     /gene="thiI"
                     /locus_tag="ACL3S0_001256"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGR1312163.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            21028..21852
                     /locus_tag="ACL3S0_001257"
     CDS             21028..21852
                     /locus_tag="ACL3S0_001257"
                     /inference="COORDINATES: protein motif:HMM:NF012958.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="HGR1312164.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            21865..23031
                     /locus_tag="ACL3S0_001258"
     CDS             21865..23031
                     /locus_tag="ACL3S0_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR1312165.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            23539..25032
                     /locus_tag="ACL3S0_001259"
     CDS             23539..25032
                     /locus_tag="ACL3S0_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR1312166.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25045..26166
                     /locus_tag="ACL3S0_001260"
     CDS             25045..26166
                     /locus_tag="ACL3S0_001260"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR1312167.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVAQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            26226..26462
                     /locus_tag="ACL3S0_001261"
     CDS             26226..26462
                     /locus_tag="ACL3S0_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGR1312168.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            26459..26872
                     /locus_tag="ACL3S0_001262"
     CDS             26459..26872
                     /locus_tag="ACL3S0_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGR1312169.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            26990..27955
                     /gene="xerA"
                     /locus_tag="ACL3S0_001263"
     CDS             26990..27955
                     /gene="xerA"
                     /locus_tag="ACL3S0_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGR1312170.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            27989..29032
                     /locus_tag="ACL3S0_001264"
     CDS             27989..29032
                     /locus_tag="ACL3S0_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR1312171.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGREIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIYG
                     SGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYLF
                     YFCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVVQVDKSQFACEIA
                     IKVWRNSLKFSII"
     gene            29062..32412
                     /locus_tag="ACL3S0_001265"
     CDS             29062..32412
                     /locus_tag="ACL3S0_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR1312172.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(32918..33388)
                     /locus_tag="ACL3S0_001266"
     CDS             complement(32918..33388)
                     /locus_tag="ACL3S0_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR1312173.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(33405..35678)
                     /locus_tag="ACL3S0_001267"
     CDS             complement(33405..35678)
                     /locus_tag="ACL3S0_001267"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGR1312174.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            36025..39126
                     /locus_tag="ACL3S0_001268"
     CDS             36025..39126
                     /locus_tag="ACL3S0_001268"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGR1312175.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGQSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            39208..40215
                     /gene="pfkA"
                     /locus_tag="ACL3S0_001269"
     CDS             39208..40215
                     /gene="pfkA"
                     /locus_tag="ACL3S0_001269"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGR1312176.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            40274..41779
                     /gene="pyk"
                     /locus_tag="ACL3S0_001270"
     CDS             40274..41779
                     /gene="pyk"
                     /locus_tag="ACL3S0_001270"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGR1312177.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT        12884 a         7395 c         9104 g        12496 t
ORIGIN      
        1 tccataatat ctatagtgga tttacccact acaaatatta tagagcccaa aatcctttgt
       61 ttactaaaca agggattttt cttttgtctc tgctcctttt ttgatataat agttctatgt
      121 taaaatcaga aaaacaatca cgttatcaaa tgttaaatga agaattgtcc ttcctattgg
      181 aaggcgaaac caatgttttg gctaatcttt ccaacgccag tgctctcata aaatcacgtt
      241 ttcctaatac cgtatttgca ggcttttatt tgttcgatgg aaaggaattg gttttaggtc
      301 ccttccaagg aggtgtttcc tgcatccgta ttgcactagg caagggtgtt tgtggtgagg
      361 cagctcactt tcaggaaact gttattgttg gagatgtgac gacctatctc aactatattt
      421 cttgtgatag tctagctaaa agtgaaattg tggtgccgat gatgaagaat ggtcagttac
      481 ttggagttct ggatctggat tcttcagaga ttgaggatta cgatgctatg gatcgagatt
      541 atttggaaca atttgtcgct attttgcttg aaaagacaac atgggacttt acgatgtttg
      601 aggaaaaatc ttaatgtatc aagcacttta tcgaaaatat agaagtcaaa acttctccca
      661 gttagttggt caagaagttg tggctaagac tcttaaacaa gcggtggagc aagagaaaat
      721 aagtcacgct tatctttttt ctggtcctcg tggaacggga aaaaccagtg ttgctaaaat
      781 ctttgccaag gctatgaact gtcccaatca agtgggtggc gaaccttgca ataactgcta
      841 tatttgtcaa gcagtgacgg acggtagttt agaagatgtc attgaaatgg atgcagcttc
      901 taataatggg gtagatgaaa ttcgcgaaat tcgtgataaa tctacctata cgcctagcct
      961 tgctcgttat aaggtttata tcatagatga ggttcacatg ctgtctacag gggcttttaa
     1021 tgccctccta aagacgctgg aagaaccaac acagaatgta gtctttattt tggccactac
     1081 tgaattgcac aagattcctg ctactattct atcccgtgtg caacgttttg agtttaaatc
     1141 aattaagaca caggatatta aggaacatat tcactatatc ttagaaaaag aaaatatcag
     1201 ttctgaacca gaggctgtgg aaatcattgc cagacgggcg gaaggtggaa tgcgggacgc
     1261 cttgtctatt ttggatcaag ccctgagttt gacacaggga aatgagctga cgactgctat
     1321 ctctgaagaa attactggca ccattagcct atcagccttg gatgattatg tggcggcctt
     1381 gtctcaacag gatgttccca aagctttgtc ttgcttgaat cttctttttg acaatggtaa
     1441 gagcatgact cgttttgtga ccgatctttt gcactattta agagacttgt taattgttca
     1501 aacaggggga gaaaatactc atcatagttc agtctttgta gaaaatttgg cacttcctca
     1561 aaaaaatctg tttgaaatga ttcgcttagc aacagtgagt ttagcagata ttaagtctag
     1621 tttgcagccc aagatttatg ctgaaatgat gaccgtccgt ttggcggaaa tcaagtccga
     1681 accagcttta tcaggagcgg ttgaaaatga aattgctacg ctgagacagg aagttgcccg
     1741 tctcaaacaa gagctttcta atgtaggtgc ggttcctaaa caagttgcac cagctcctag
     1801 tcgaccagct acgggcaaaa cagtctatcg tgtcgatcgc aataaagtgc aatctatctt
     1861 acaagaggcc gtcgaaaatc ctgatttagc acgtcaaaat ttaattcgtt tgcagaatgc
     1921 ctggggagag gtaattgaaa gtctaggtgg gccggacaag gctctgctag ttggttctca
     1981 accggttgct gccaatgaac accatgctat tcttgctttt gagtctaact tcaatgctgg
     2041 tcaaactatg aaacgagaca atctcaatac catgtttggt aatatcctca gtcaggcggc
     2101 aggtttttca cctgagattt tagctatttc catggaggaa tggaaagaag ttcgcgcagc
     2161 cttttcagcc aaagccaaat cttctcaaat tgaaaaagaa gtagaagaaa gcctgattcc
     2221 agaaggattt gaatttttgg ctgataaagt gaaggtagag gaagactaaa gaaagatttc
     2281 atgatacaat aagtttatga ataaacaaca atttattatt atggcgctgt ttacagctgc
     2341 tgagacctat tttttcaatg aagcctggat gactggtcgc tatattatgg cagccttttg
     2401 ggcaatttta ctctttagaa atttccgagt cagttatgtg atgggcaaaa tcgttgatgt
     2461 catcgatcag cattttaata ggaaagacta gccctcagct tccagacaaa atcaaagcct
     2521 tttaggcttt tttttgttat actagaaaag tatatttata gaatttttgc tctatttctg
     2581 gggaaatcag acgtttttct agtaagtact gtaaaagttt tgaaaaagaa aggaactatc
     2641 atgtcagtat tagagatcaa agatcttcac gttgagattg aaggaaaaga aattttaaaa
     2701 ggggttaacc tgaccctgaa aacaggagaa attgccgcta tcatgggacc aaatggtaca
     2761 ggtaaatcga ctctttctgc cgctatcatg ggaaatccaa actatgaagt aactaaaggt
     2821 gaagttttgt ttgatggcgt aaacatcctt gagttggaag tggatgagcg tgcgcgtatg
     2881 ggacttttcc ttgctatgca atacccatca gaaatccctg gaattaccaa tgctgagttt
     2941 cttcgtgccg ctatgaatgc gggtaaagaa gatgatgaga agatttcagt tcgtgagttt
     3001 attactaagc tagatgaaaa aatggaattg ctcaacatga aagaagaaat ggcagagcgt
     3061 tacctcaacg aaggcttctc tggtggtgag aaaaaacgca atgaaattct tcaacttttg
     3121 atgttggagc caacatttgc tcttttggac gagattgact caggtcttga tattgacgct
     3181 cttaaagttg tgtctaaagg tgtcaatgcc atgcgtggtg aaggttttgg tgctatgatc
     3241 atcactcact accaacgtct tttgaactat atcacacctg atgtggtaca cgtgatgatg
     3301 gaaggtcgtg ttgtcctttc tggtggtcca gaattggctg cgcgtttgga acgtgaagga
     3361 tacgcaaaac tagctgaaga acttggctac gactacaagg aagaattgta attccctcgt
     3421 atcttttagg agaagtaaat gactagagaa aatattaaac ttttttcaga aatgcacgct
     3481 gaaccaagct ggttggctga tctccgtcaa aaagcttttg acaagattga gactttggaa
     3541 ttaccagtta ttgagcgtgt caaattccac cgttggaatc tgggtgatgg aacgattaca
     3601 gaaaatgagc catcagcaaa tgttccagat ttcacagctt tagatcatca cttgaagttg
     3661 gtgcaagtag gaactcaaac tgttttcgaa caaactccag ttgagttagc tgaacagggt
     3721 gttgtcttca cagactttca ctcagcttta gaagaaattc cagagctgat cgaagaattc
     3781 ttcatgtcat ctgttaagta tgatgatgac aagttggcgg cttaccacac agcttacttt
     3841 aacagtggtg ctgtactcta tattccagat aacgtagaaa ttacagagcc aattgaagga
     3901 attttctacc aagatagcga tagcaatgtg ccgtttaaca agcatattat gattatcgct
     3961 ggtaaaaatt ctaagattag ttatctggag cgtttagagt cacgcggtga aggaagtgac
     4021 aaagcaactg ccaatatcac agtggaagtg attgcacgtt ctggtgcgca agtcaagttt
     4081 gctgctatcg accgtctagg tgaaaacgtc actgcctaca ttagccgtcg tggtaaatta
     4141 ggcaacgatg caagtattga ctgggctatc ggtgtcatga acgaaggaaa tgtcgttgct
     4201 gattttgata gtgacttgct tggaaatggt agccatgcgg acctcaaggt agtagcactt
     4261 tcaagtggtc gtcaggtgca agggattgat actcgcgtga ctaactatgg ttgcaactct
     4321 atcggaaata tcctacaaca tggggttatc cttgaaaaag caactttgac tttcaatggt
     4381 atcggccaca tcatcaaggg tgctaaggga gcagatgccc aacaagagag ccgtgttctc
     4441 atgctttcag accaagcgcg ttcagatgct aacccaattc ttttgattga tgaaaatgat
     4501 gtcactgcag gacacgcagc gtctatcgga caagttgatc cagaagacat gtattacctc
     4561 atgagtcgtg gattggataa ggcaactgca gagcgtttgg ttgttcgtgg tttccttgga
     4621 tctgttatcg tggagattcc agtcaaggaa gttcgtgatg aaatgattgc aactatcgaa
     4681 gagaaattgt caaaacgcta aggggaagcc tatgttagat gtagaagcga ttcgcaagga
     4741 ttttccaatt ttagatcaga ttgtcaatga tgaacctctg gtctatctgg acaatgctgc
     4801 gacgacacaa aaaccactag tagttctgaa agctattaac agctactatg aacaggacaa
     4861 tgccaatgtt caccgtggtg tccatacctt agcggaacga gcgacagctt cttatgaagc
     4921 tgctcgtgaa accattcgta agtttattaa tgcatgctct acaaaggaag ttctctttac
     4981 cagaggaacg acaaccagcc ttaactgggt ggcacgcttt gctgaggaaa ttctcactga
     5041 gggagaccag gtcttgattt cagtaatgga acaccattct aatatcattc catggcagga
     5101 agcttgtcga aagactggag cagagcttgt ctatgtctat cttaaagacg gtgccttgga
     5161 tatggaggat ttgcgagcta aattgactga taaggttaaa tttgtttccc tagctcatgc
     5221 ctccaatgtt cttggtgtgg tcaatccgat taaggaaatc actcaattag cccaccaagt
     5281 tggggcaatc atggtagtgg atggtgctca atctacacct catatgaaga ttgatgtcca
     5341 ggacttggat ctggactttt tcgccttttc gggtcacaag atggctggtc cgactggtat
     5401 cggtgtcctt tacggcaaag aaaagtatct tgagcaaatg tctccagtag aatttggcgg
     5461 cgagatgatt gattttgtct acgagcaatc cgctagttgg aaggaattgc cttggaaatt
     5521 tgaggctgga acgccaaata tggcaggagc tattggactt gcgactgcag ttgattatct
     5581 ggaaaagatt ggtatggatg ccgttgaagc tcatgaacag gaattgattg cgtacgtcta
     5641 tccaaaactg caggcaattg agggattgac catttacggt tctcaggatt tggctcaacg
     5701 ttcgggtgtt attgccttta acctaggtga tctccatcct cacgatcttg cgacggctct
     5761 ggattatgaa ggagtggctg ttcgtgctgg tcaccattgt gcgcaaccct tgcttcagta
     5821 tttggaagtc ccagcatcag ctcgtgcaag tttttatatc tacaatacca aggcagattg
     5881 cgacaaacta gtcgatgccc tacaaaagac aaaggagttt ttcaatggca ctttctaaac
     5941 tagatagcct ttatatggca gtggtagcag accattcgaa aaatccacat caccaaggga
     6001 agttagaaga tgctgagcaa atcagtctca acaatccgac ttgtggggat gtcatcaacc
     6061 tctctgtcaa gtttgatgca gaggaccgtt tggaagatat tgcttttcta aattcaggat
     6121 gcacgatttc aactgcttct gctagtatga tgacagatgt cgttttagga aaaaccaaac
     6181 aagaaatttt agaactggcg actatttttt ctgaaatggt tcaagggcaa aaagatgagc
     6241 gtcaaggcca acttggagac gcggcattct tgtcaggtgt tgccaaattc cctcaaagaa
     6301 tcaagtgtgc aaccctagct tggaatgccc ttaagaaaac aattgaaaat caagaaaaac
     6361 agtaagacaa gtttcttttg tcttatgaat tattagaaat gaagaaagaa aggatactat
     6421 ggctgaagaa agagtagaac caaaaccaat tgaccttggt gaatataaat ttggtttcca
     6481 tgacgatgta gagcctgtct tatcgacagg aaaaggactc aacgaaggtg ttattcgtga
     6541 attatctgct gctaagggtg agcctgagtg gatgttggag ttccgtttga agtcttatga
     6601 aaccttcaaa aaaatgccca tgcaaacttg gggagcagac ttgtcagaga ttgactttga
     6661 tgacttaatc tactaccaaa aaccatctga caaaccagcc cgttcttggg atgatgtacc
     6721 tgaaaagatt aaagaaacct ttgaacgtat cgggattcca gaagctgaac gtgcttattt
     6781 agcaggggct tctgcccagt acgagtcaga agtggtttac cacaacatga aggaagagtt
     6841 ccaaaaatta ggtattatct ttacagatac agattccgca ctcaaggaat acccagactt
     6901 atttaaacaa tactttgcga agttggtacc gccgacagat aacaagttgg cagccctcaa
     6961 ctcagcagta tggtcgggtg gaacttttat ctacgtgcca aaaggtgtca aggtagatat
     7021 tccacttcaa acttatttcc gtatcaataa cgaaaatata ggtcagttcg aacgtacctt
     7081 gattatcgtt gatgagggag caagcgtcca ctacgtagaa ggatgtacag caccaacata
     7141 ttcaagcaat agcttacacg ctgccattgt agaaattttt gctttggacg gagcttatat
     7201 gcgttataca actatccaaa actggtctga taacgtctat aacttggtaa caaagcgtgc
     7261 taaggctcaa aaggatgcca ctgttgagtg gattgatgga aacttgggtg ccaaaacgac
     7321 tatgaaatat ccatctgttt accttgatgg agaaggagcg cgtggtacca tgctctctat
     7381 cgcctttgct aatgcagggc aacaccaaga cacgggtgct aagatgattc acaatgctcc
     7441 acataccagc tcgtctattg tgtctaaatc catcgctaaa ggtggaggaa aggttgacta
     7501 ccgtggacaa gtcaccttta acaagaactc taagaaatct gtttcccaca ttgaatgtga
     7561 taccattatc atggatgact tgtcagcatc agatactatt ccatttaatg aaattcacaa
     7621 ctcgcaagta gctttggaac acgaagccaa agtatctaag atttcagaag agcaattgta
     7681 ttatctcatg agccgtggat tgtcagaatc tgaggcaact gaaatgattg tcatgggatt
     7741 tgtagaaccc tttacaaaag aacttccaat ggaatacgca gttgagctga accgcttgat
     7801 tagctatgaa atggagggat cagttggata aaatttgatt ttatactctt cgaaaatctc
     7861 ttcaaaccac gtcagcatcg ccttaccgta tgtatggtta ctgacttcgt cagtttcatc
     7921 tacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagtta gttctttgat
     7981 tttgagtatt agatttactc aaaatcaagg attttgaaga tgaacttgta tcaaaaaatc
     8041 gcggtttaaa atcgcgattt tttataattt ctcgttaaca aagcggacaa actgattcca
     8101 ccaaactttt aagaagaagg ctttttcaat tttcttgtct gctaccattt cgaaactagg
     8161 gcgctctgtg gtgatgtaac cttgaccaat caagtccttg tcttcataag tcaaatggcc
     8221 aaccactgtt ccagcttcaa gtggtgctgg gattgctttg gaatcaggtg tgaattgaac
     8281 agattgggaa gattgattcc caacacgttc gattagatag atatcctctg gagccactgc
     8341 agttactgta tcttcttttc catcttgtac aggggctttg ctatcttgat aggcatcgcc
     8401 ttgttgaacg attttgcgaa gtgtaaatgt agaagaaata taatccatta gggaagatgt
     8461 agctgtaaat cgagcgtaag gattattgtc ttgatgatct gcatttaaaa caactgtgat
     8521 gactctcatg cctttttcga cagtagtacc aacaaaagac tctccagcct tatctgttgt
     8581 tcctgttttt agcccatcaa aaccaccacg gtaagcaggc ataccttcta acatgtagtt
     8641 ggttgaagtg attgtcatcc cagcaaaagt agaagaaggt tttttggtga tttctaagac
     8701 ttgtgggtat tttttgatga ggttgcgagc aacgatagcg acatcataag cactaagctt
     8761 attttcctca tcttttttag aacctgggta aatgttatcc cctagagttt cattgttaag
     8821 acctgtcgta ttgacaacag tggcatcctg aattccccat tccaagagtt ttgcccgcat
     8881 catatcgacg aaatcttttt ctgagccagc aattttctca gctagggcaa tagcggcgct
     8941 gttggcacta gataccagag ttgcttcaag caactcttcg acagtataat tacgggcctc
     9001 cataggaata ttactggctt cagaatttgt cgtcaattga taaggataat cagaaatatc
     9061 tacaggagtg gagagggtaa tacttccgtt ttccaaagct tcatagacca gataaacagt
     9121 aatcaatttt gttatggaag caatttcgac aggttgcgtt gcatccttct catagagaat
     9181 tttaccagta tttgcctcaa cagcaatcgc atgtttagcg gcaatggtaa aatcttgagc
     9241 aacagcagta gaagcacccc ctaaaagaga gacagttaac aaagttaaaa atattttttt
     9301 catagtagtc ttattctatc ataaagaaaa aaaatattct tgctttaata attcatctgt
     9361 taagcttttt gaaaatatgg taaaataaag tgagggaggt aactcatgtt tcgtagaaat
     9421 aaattatttt tttggaccac agaaatttta ctcttaacca tcatctttta tctatggaga
     9481 cagatggggt ctttgattaa cccttttgtt agcgtgctta atacaattat gattccattt
     9541 ttattagggg gctttcttta ttatttgaca aaccctattg ttactttctt aaataaagtc
     9601 tgtaaactca atcgtttgct tggtatttta attaccttgt gtactttgat ctggggaatg
     9661 gtcataggtg ttgtctatct cttacctatt ttgattaatc agttatctag tttgattata
     9721 tctagtcaaa ctatttatag tcgagtacaa gacttaatca tagacttatc taattatcct
     9781 gcgctccaga atttggatgt agaagctaca attcagcagt taaacttatc ctatgttgat
     9841 attcttcaaa atatcctaaa tagcgtatca aatagtgtgg ggagcgtctt gtcagctctt
     9901 atcagtactg ttttgatttt gattatgact ccagtttttt tggtttattt cttattagat
     9961 ggacataaat tcttgcccat gcttgaaaga acgattctaa agagggatcg cttgcatatt
    10021 gcaggcttat taaagaattt aaatgcgacg attgctcgct atattagtgg agtttcgatt
    10081 gacgcaatca ttataggttg tttggcttat attggctata gtattattgg tttaaaatat
    10141 gctttagttt ttgccatttt ttctggtgta gccaatttaa ttccttatgt ggggccaagt
    10201 attggtttga ttcctatgat catcgcaaat atattcactg atccccatag actgctgatt
    10261 gcagtgattt atatgcttgt tgttcagcag gtagatggca atatcttata tcctcgaatc
    10321 gtaggaagtg ttatgaaggt tcatccaatc acgattttag ttttactttt gttgtcaagc
    10381 aatatctatg gtgtagttgg aatgattgtc gcagtgccaa cctattctat cttgaaagaa
    10441 atttctaagt tcttatcccg tttgtatgaa aatcataaaa taatgaaaga acgagaaaga
    10501 gaattagcta agtaaaagtc aggagaaccc tgatttttct ttactggaag tggcctttag
    10561 attagaagac tgaaaataag ttaaagtctt aaactaattt tcacagctaa gaatagtaga
    10621 agttaatctg ataaaaatcg aaaaaaccag tggaattccg tgtcagggta agttccactg
    10681 gttttcatag tctattaaag ttcgaatgaa acctatttat agtatattga aactagaata
    10741 gtacacctct aattctaaaa cattgttaga aatcgatttg actgtcctga tctattcgtc
    10801 ctattcttat ttcattttac tatattttgg tgcaataagt gaaaagtagt ccgaataata
    10861 taaggattga ttttatagtt tttaaactca aatgaattaa aataaagaga gtacgaaaat
    10921 tctcatctga aagtatttta gaataattct cttcgtgaat ttcttcaaaa cagatagctt
    10981 catcttaggt atgtgttaat tggatttcgt aagctctatt tacaatcgta aagttatgca
    11041 ctgaaaaagt tgtagttagt cttccagttt gctaaatttc tcgaatagta tcttttttag
    11101 gtatgtgatt tctttttgca tttttgagtt agataaggta taatggtttt attgtctttt
    11161 ggggtcgtta cggattcgac aggcattatg aggcatattt tgcgactcgt gtggcgacgt
    11221 aaacgctcag ttaaatataa ctgcaaaaaa taacacttct tacgctctag ctgcctaaaa
    11281 accagcaggc gtgacccgat ttggattgct cgtgttcaat gacaggtctt attattagcg
    11341 agatacgatt aagccttgtc tagcggtttg ataagagatt gatagactcg cagtttctag
    11401 acttgagtta tgtgtcgagg ggctgttaaa ataatacata acctatggtt gtagacaaat
    11461 atgttggcag gtgtttggac gtgggttcga ctcccaccgg ctccattatt cctttgcatt
    11521 ccttggtaaa acgttgttaa atcaacgttt tttattttta tctttggtat tcctttgcat
    11581 tcttttgcta aaaagggagt cacaaacaga ccctatttta aaaaaaggat agaaaaaagg
    11641 atacaacatt tgtcgcatcc taaaaataat cttttttcga cggaagacat gggattcgaa
    11701 cccacgcacg ctattacacg cctaccgcgt ttccaacacg gcctcttaag cctcttgagt
    11761 aatcttccaa tacttactca aatagtctac cataaaggct cttatcttgc aataaaaatt
    11821 ctagaaataa gaaaaaatga tagattttga aagaaaatga taaaaaatgc ttgacttcga
    11881 aagaaagtat ggtagaatga atagtgtaaa cgataacagg aggtgattca gtgttaaaaa
    11941 cagaacgtaa acaactgatt ttagaggagt taaatcaaca tcatgtagtt tctctagaaa
    12001 aattagttag tttgctagaa acgtcagaat caacggttcg aagagacttg gatgagttgg
    12061 aagcggaaaa caagcttcgt cgtgtgcatg gtggagcaga actcccccac tccttacagg
    12121 aagaagaaac cattcaagaa aaatctgtca aaaaccttca agaaaagaag ttgctggctc
    12181 agaaagcagc ctctctcatt aaagaaaaag atgtcatctt tatcgatgct ggaacaacaa
    12241 ctgctttttt gattcatgaa ttggtcaata agaatgttac agttgtgacc aactccattc
    12301 accatgccgc tcagttggtt gaaaagcaga ttccaactgt catggttgga ggaaacgtca
    12361 agacggcgac agatgctagt atcggtggcg ttgctcttaa ccagattaac caattgcact
    12421 ttgaccgtgc ctttatcgga atgaatggtg ttgacgatgg ctattatacg actcctgata
    12481 tggaggaggg agctgtgaaa agagctattt tggagaatgc caagcagacc tacgtcttgg
    12541 tggattcgtc aaaaattgga caaacttgct ttgccaaggt agcaccactc aaacgcgcta
    12601 tcgttatcac tagtcaaggg catgagctct tgcaggttat taaggagaaa acggaggtaa
    12661 tagaagtatg atttatacag tcacactcaa tccatccatt gactatatcg ttcgtttgga
    12721 ccaagtcaaa gttggtagtg taaatcgtat ggacagtgat gataagtttg ctggtgggaa
    12781 aggaatcaat gtcagccgtg tcttgaaacg tttgaatata ccaaatacag cgacgggatt
    12841 tatcggtggc tttactggta aatttatcac agatacttta gcagaggaag aaatcgagac
    12901 acgttttgtc caggtggcag aagatactcg tatcaatgtt aaaatcaaag cagaccaaga
    12961 aacagaaatc aacggaacgg gtccaactgt tgaatcggtt cagctagaag aattgaaagc
    13021 tattttatct agtctgacag cagaagatac agttgtcttt gcaggttcaa gtgctaaaaa
    13081 tctaggcaat gttatctata aggatttgat ttccttgacg cgccagactg gtgcgcaagt
    13141 ggtctgtgac tttgaaggac agaccttaat tgatagtttg gactaccagc ctcttcttgt
    13201 aaaaccaaac aatcatgaac ttggagcgat ttttggggtt aaactcgaaa gtttagatga
    13261 aattgagaaa tacgctcgtg agttactggc taagggtgct caaaatgtta ttatctctat
    13321 ggctggtgat ggtgcccttc ttgtcacatc tgatggagct tacttcgcta aaccaatcaa
    13381 gggaacagtc aaaaattcag ttggagctgg tgattctatg gttgctggat tcacaggtga
    13441 atttgtcaaa tcaaaagacg cagtagaagc cttcaaatgg ggagtggctt gcggaacggc
    13501 aactaccttc tcagatgact tggcaacggc ggaatttatt aaagaaacat atggaaaagt
    13561 tgaggtagaa aaacgatgaa aattcaagac ctattgagaa aagatgtcat gttgctagat
    13621 ttgcaggcaa ctgaaaaaac agctgtcatc gacgagatga ttaaaaattt gacagaccac
    13681 ggttatgtaa cagattttga aacatttaaa gaaggaattt tggcgcgtga agctttgact
    13741 tctactggtt tgggtgatgg aatcgcaatg cctcacagca aaaacgctgc tgtcaaagaa
    13801 gcgacagttc tatttgctaa gtcaaataag ggtgttgact acgagagctt ggatggacaa
    13861 gcaactgacc tcttcttcat gattgcagct ccagaaggtg ccaatgatac tcacttggca
    13921 gccttggcag aattgtctca atacttgatg aaagacggtt ttgcagacaa acttcgtcaa
    13981 gcaacatctg cagaccaagt tatcgaactt tttgaccaag cttcagaaaa aactgaggaa
    14041 cttgttcaag cacctgctaa tgactctggt gactttatcg tagctgttac agcttgtaca
    14101 acaggtattg cccacactta catggcccaa gaagcccttc aaaaagtagc tgctgaaatg
    14161 ggggttggta tcaaggtcga aaccaacggt gctagcggtg ttggaaatca actaactgca
    14221 gaagatatcc gtaaggctaa agctattatc attgcagcag acaaggccgt tgaaatggat
    14281 cgatttgatg gaaaaccatt gatcaatcgt ccagttgctg acggtatccg taagacagaa
    14341 gagctaatta acttggctct ttcaggagat actgaagtct accgtgccgc taatggtgcc
    14401 aaagctgcaa cagcctctaa cgaaaaacaa agccttggtg gtgccttgta caaacacttg
    14461 atgagtggtg tatctcaaat gttaccattc gttatcggtg gtggtatcat gattgccctt
    14521 gccttcttga ttgacggtgc tttgggtgtt ccaaatgaaa accttggcaa tcttggttct
    14581 taccatgagt tagcttctat gttcatgaaa attggtggag ctgcctttgg tttgatgctt
    14641 ccagtctttg cgggttatgt tgcctactct attgctgaaa aaccgggttt ggtagcaggt
    14701 ttcgtggctg gtgctattgc caaagaaggt tttgcctttg gtaaaattcc ttatgccgca
    14761 ggtggtgaag caacttcaac tcttgcaggt gtctcatctg gtttcctagg tgcccttgtt
    14821 ggtggattta tcgcaggtgc cttggttctt gccatcaaga aatacgttaa agttcctcgt
    14881 tcactcgaag gtgctaaatc aatccttcta ttgccacttc ttggaacaat cttgacagga
    14941 tttgttatgc tagctgtgaa tatcccaatg gctgcaatca acactgctat gaatgacttc
    15001 ctaggcggtc ttggaggagg ttcagctgtc cttcttggta tcgtccttgg tggaatgatg
    15061 gctgttgaca tgggtggacc agttaataaa gcagcttatg tctttggtac aggtacgctt
    15121 gcagcaactg tttcttcagg tggttctgta gccatggcag cagttatggc tggaggaatg
    15181 gtgccaccac ttgcaatctt tgtcgcaact cttcttttca aagataaatt tactaaggaa
    15241 gaacgtaact ctggtttgac aaacatcatc atgggcttgt catttatcac tgagggagcg
    15301 attccatttg gtgccgctga cccagctcgt gcgattccaa gcttcatcct tggttcagca
    15361 gtagcaggtg gactcgttgg tcttactggt atcaaactca tggcgccaca cggaggaatc
    15421 ttcgttatcg cccttacttc aaatgctctc ctttacctcg tttctgtctt ggtaggagca
    15481 atcgtaagtg gtgtggttta tggttaccta cgcaaaccac aagcataaaa aatagaaaaa
    15541 tgaaaagatt ggaccgtttg gtgcagtctt tttctcttcc cgaaatgcct gtgaaatatg
    15601 gtataataga agaatggcaa acaagaatac aagtacaaca agacggagac cgtctaaagc
    15661 agaactggaa agaaaagaag cgattcaacg aatgttgatt tcgttaggaa ttgcgatttt
    15721 attgattttc gcagccttca aattaggggc tgcaggtata accctttata atttaattcg
    15781 cttgctagtg ggtagcctag cttatctggc gatattcggc ctattaatct atctcttctt
    15841 tttcaagtgg atacgaaaac aggaaggact cttatctggc tttttcacca tatttgctgg
    15901 cttactcttg atttttgagg cctacttggt ttggaaatat ggtttggaca agtccgttct
    15961 aaaagggacc atggctcagg ttgtgacaga tctgactggt tttcgaacga ctagctttgc
    16021 tggagggggc ttgatcgggg tcgctcttta tattccaaca gcctttctct tttcaaatat
    16081 cggaacttac tttattggtt ctatcttgat tttagtgggt tctctcctag tcagcccttg
    16141 gtctgtttac gatattgctg aatttttcag tagaggcttt gccaaatggt gggaagggca
    16201 cgagcgtcga aaagaggaac gctttgtcaa acaagaagaa aaagctcgcc aaaaggctga
    16261 gaaagaggct agattagaac aagaagagac tgaaaaagcc ttactcgatt tgcctcctgt
    16321 tgatatggaa acgggtgaaa ttctgacaga ggaagctgtt caaaatcttc cacctattcc
    16381 agaagaaaag tgggtggaac cagaaatcat cctgcctcaa gctgaactta aattccctga
    16441 acaggaagat gactcagatg acgaagatgt tcaggtcgat ttttcagcca aagaagccct
    16501 tgaatacaaa cttccaagct tacaactctt tgcaccagat aaaccaaaag atcagtctaa
    16561 agagaagaaa attgtcagag aaaatatcaa aatcttagaa gcaacctttg ctagctttgg
    16621 tattaaggta acagttgaac gggccgaaat tgggccatca gtgaccaagt atgaagtcaa
    16681 gccggctgtt ggtgtaaggg tcaaccgcat ttccaatcta tcagatgacc tcgctctagc
    16741 cttggctgcc aaagatgtcc ggattgaagc accaatccct gggaaatccc taatcggaat
    16801 tgaagtgccc aactccgata ttgccactgt atctttccga gaactatggg aacaatcgca
    16861 aacgaaagca gaaaatttct tggaaattcc tttagggaag gctgttaatg gaaccgcaag
    16921 agcttttgac ctttctaaaa tgccccactt gctagttgca ggttcaacgg gttcagggaa
    16981 gtcagtagca gttaacggca ttattgctag cattctcatg aaggcgagac cagatcaagt
    17041 taaatttatg atggtcgatc ccaagatggt tgagttatct gtttacaatg atattcccca
    17101 cctcttgatt ccagtcgtga ccaatccacg caaagccagc aaggctctgc aaaaggttgt
    17161 ggatgaaatg gaaaaccgtt atgaactctt tgccaaggtg ggagttcgga atattgcagg
    17221 ttttaatgcc aaggtagaag agttcaattc ccagtctgag tacaagcaaa ttccgctacc
    17281 attcattgtc gtgattgtgg atgagttggc tgacctcatg atggtggcca gcaaggaagt
    17341 ggaagatgct atcatccgtc ttgggcagaa ggcgcgtgct gcaggtatcc acatgattct
    17401 tgcaactcag cgtccatctg ttgatgtcat ctctggtttg attaaggcca atgttccatc
    17461 tcgtgtagca tttgcggttt catcaggaac agactcccgt acgattttgg atgaaaatgg
    17521 agcagaaaaa cttcttggtc gaggagacat gctctttaaa ccgattgatg aaaatcatcc
    17581 agttcgtctc caaggctcct ttatctcgga tgacgatgtt gagcgcattg tgaacttcat
    17641 caaggctcag gcagatgcag actacgatga gagttttgat ccaggtgagg tttctgaaaa
    17701 tgaaggagaa ttttcggatg gagatgctgg tggtgatccg ctttttgaag aagctaagtc
    17761 tttggttatc gaaacacaga aagccagtgc atccatgatt caacgtcgtt tgtcagttgg
    17821 atttaaccgt gcgacccgtc tcatggaaga gcttgagatg gcaggtgtca ttggtccagc
    17881 tgaaggtacc aaaccaagaa aagttttaca acaataaaaa aatagcttct ttccaagttt
    17941 ggaaggaggc tattttagtg gttattgatt acttttattt tctgaagttg gagtattggg
    18001 ctgtttttca ttttcagtgg caggtttact tgtagcaggt gtagtagagt cctgagttgc
    18061 tgttttctga tcttcttttt tctcttcctt gacgctagat tttggtgttt cctcttgctg
    18121 tgttttttct tgactagtgt tagtctcttt agttggactg gtgttttcct taggggattc
    18181 cttttggatt tctttgacaa tggttgtcgt ctggcttgtc gtaggttctt ttttaatatt
    18241 tttgttatta tccaaggcgt tcatgatcgt gatactcgcg gtaatcaagc caaggatact
    18301 agcgattgta gcaacggttt tttgaaagac tgtaaagcct tttttgatgt gttctgtttt
    18361 tggttttgaa gttctacgat agttagacat acattctctc ctttgattat gatttattat
    18421 actctgtttc tttaaaaaaa tcttaaaaaa agagaaattg ccctttcttg tcgcaagctc
    18481 cgtttcatga tacaatagag gaagtgattt tagaaagcgt gagaaacatg atttactttg
    18541 ataattcagc gacgaccaag ccttatcctg aagcccttga aacctatatg caggtcgctt
    18601 caaaaatttt aggaaaccca tctagtctcc atagtttggg agaccaagca acacgaatct
    18661 tagatgcttc tcgccaacag attgcagatt taatcggtaa gaaaagcgat gaaatcttct
    18721 ttacctctgg tggaacagaa ggggataact gggttatcaa gggtgtggcc tttgaaaaag
    18781 ctcagtttgg caagcacatc attgtttcag ccattgaaca tccagcagtc aaagagtcag
    18841 ccctctggtt gaaaagtcaa ggatttgaag tggattttgc tccagttgat aacaaaggat
    18901 ttgtggatgt tgaggcgcta gaagatttga taagacctga tacgaccctc gtttccatca
    18961 tggctgtgaa caatgaaatc ggctctatcc aacctattga ggctatttca gaattcttgg
    19021 cagacaagcc aactatttcc ttccacgttg atgcggttca ggcgcttgcc aagattccga
    19081 ctgaaaagta tctgacagaa cgagtggatt tcgcgacttt ctctggtcac aagttccacg
    19141 gaatccgtgg tgttggtttt atctatatca agtctggcaa gaagattacg cctcttttaa
    19201 caggtggtgg tcaggaacgt gattaccgtt cgacaactga aaatgtggca ggaattgcag
    19261 cgaccgctaa ggctctccgt ttatctatgg aaaagctaga tatctttagg agcaagactg
    19321 ggcagatgaa ggcagtgatt cgtcaagcac ttctggacta tccggatata tttgtctttt
    19381 cagatgagga agacttcgcc cctcatattc tgacttttgg aatcaagggt gttcgtggtg
    19441 aggtcattgt tcacgccttt gaagactatg atattttcat ctcaacgacc tcggcttgtt
    19501 cgtccaaggc tgggaaacca gccggaaccc tgattgctat gggagtggac aaggataagg
    19561 ctcagtcagc tgtgcgtctt agtctagacc ttgaaaatga tatgagtcag gtcgagcagt
    19621 tcttgaccaa gctaaaatta atttacaatc aaactagaaa agtaagatag gagcattcat
    19681 gcagtattca gaaattatga ttcgctacgg tgagctgtca accaagggca aaaatcgtat
    19741 gcgtttcatc aataaacttc gcaataatat ttcagacgtt ttgtctatct atccccaagt
    19801 taaggtaaca gcagatcgcg accgtgccca cgcttacctc aatggagcag attacacagc
    19861 agtagcagaa tcgctcaaac aagtatttgg aattcaaaac ttttcccctg tttataaggt
    19921 tgaaaaatct gtagaagttc tgaagtctgc tgtccaagag attatgcagg acatctacaa
    19981 ggaaggcatg acctttaaaa tctctagcaa gcgtagcgac cacacctttg aattggacag
    20041 tcgtgaactc aaccaaacgc ttggaggggc tgtattcgaa gccattccaa acgtacaagc
    20101 tcaaatgaaa agtcctgaca tcaatcttca ggtggagata cgtgaagaag cagcctatct
    20161 ttcttatgaa accgttcgag gggcaggtgg attaccagtg ggaacttctg gtaagggcat
    20221 gctcatgttg tcagggggaa tcgattcccc tgtagctggc tatctagcgc ttaaacgagg
    20281 ggtagatata gaggcagttc actttgccag cccaccttac acgagtcctg gtgctcttaa
    20341 aaaagcccaa gatttgaccc gtaaattaac caaatttggg ggaaatatcc agtttatcga
    20401 agttcctttt acagagattc aagaggaaat caaagccaaa gcgccagaag cctaccttat
    20461 gaccttgacg cgtcgtttta tgatgcgtat tactgaccgt attcgtgagg tacgaaatgg
    20521 tttagttatc atcaatgggg aaagtctagg tcaagtagcc agccaaaccc ttgaaagtat
    20581 gaaggctatc aatgctgtta ccaacactcc catcattcgt cctgtggtta ccatggacaa
    20641 gttggaaatc attgacatcg cccaggaaat cgataccttt gacatttcaa tccaaccgtt
    20701 tgaagactgt tgtaccattt ttgcaccaga tcgtccaaaa acaaatccta aaattaagaa
    20761 tgcggagcag tacgaagcgc gtatggatgt tgaaggcttg gttgagcgag cagtggctgg
    20821 aatcatgatt actgaaatca cacctcaagc cgaaaaagat gaagttgatg acttgattga
    20881 caatctgctc taattcagaa aatccaaaag aatagcgaaa atcagtaaaa aaagttagtt
    20941 ttttctctaa aaacaggtaa aaaactaact ttttttattt ttatgatata atgatataaa
    21001 attttgaata tagagagttt tctgacaatg aatcaatcct acttttatct aaaaatgaaa
    21061 gaacacaaac tcaaggttcc ttatacaggt aaggagcgcc gtgtacgtat tcttcttcct
    21121 aaagattatg agaaagatac agaccgttcc tatcctgttg tatactttca tgacgggcaa
    21181 aatgttttta atagcaaaga gtctttcatt ggacattcat ggaagattat cccagctatc
    21241 aaacgaaatc cggatatcag tcgcatgatt gtcgttgcta ttgacaatga tggtatgggg
    21301 cggatgaatg agtatgcggc ttggaagttc caagaatctc ctatcccaga gcagcagttt
    21361 ggtggtaagg gtgtggagta tgctgagttt gtcatggagg tggtcaagcc ttttatcaag
    21421 cacaaaacag gttggtttga tggcatgatg acgacaggtt gctctatggg agcctatcat
    21481 gcactcaatt tcttcctcca gcatccagat gtctttacca aagtgattgc tctcagtggt
    21541 gtttacgacg cacgtttctt tgtcggtgat tactacaacg atgatgctat ttaccaaaac
    21601 tcgccagtag attatatttg gaaccaaaac gatggctggt ttattgaccg ttaccgtcag
    21661 gcagagattg tgctgtgtac ggggcttgga gcctgggaac aagatggttt accatccttt
    21721 tacaagctca aagaagcctt tgaccagaaa caaattccag cctggtttgc tgaatgggga
    21781 catgatgtcg cccacgactg ggaatggtgg cgtaaacaaa tgccttattt cctcggtaat
    21841 ctctatttat aaaaggagtt acctatgaat taccttgtta tttctcccta ctatccacaa
    21901 aactttcaac agtttaccat cgaactagct aataaaggca tcacagtctt gggaattggt
    21961 caagagtctt acgagcaatt ggatgagccc ttgcgcaata gcttgaccga gtattttcgt
    22021 gttgataatc ttgagaacat agatgaagtc aaacgtgcag ttgcttttct cttttataaa
    22081 catggtccaa ttgaccgcat cgagtctcac aatgaatact ggcttgagct agacgcaaca
    22141 ctcagagaac aattcaatgt ttttggtgcc aaaccagagg atctcaaaaa gacgaaatat
    22201 aagtctgaaa tgaagaaact tttcaaaaaa gcaggtgttc ctgtggtacc tggagctgtt
    22261 atcaagacgg aagcagatgt tgatcaagca gtgaaagaaa tcggtcttcc aatgattgcc
    22321 aaacctgata atggagtggg agcagccgca acctttaaac ttgagacaga agacgatatc
    22381 aatcacttca agcaagaatg ggaccattca accctttatt tctttgaaaa atttgtcact
    22441 tccagcgaaa tctgtacctt tgacgggctc gtggacaagg atggaaagat tgtcttctca
    22501 acaacctttg actacgccta tacaccgctt gacctcatga tttataagat ggacaattct
    22561 tattatgtgc tcaaggatat ggatcctaaa ctgcgcaagt atggggaagc aattgtcaaa
    22621 gaatttggta tgaaagaacg gtttttccat attgagttct tccgtgaggg ggacgattat
    22681 attaccatcg agtacaataa ccgccctgca ggtggtttta ccattgatgt ttataacttt
    22741 gctcattcct tggaccttta tcgtggctat gcagctattg tcgcaggaga ggagttcccg
    22801 gcgtcagact ttgaaactca gtattgtttg gctacttctc gccgtgcaaa tgctcactat
    22861 gtttattcag aagaggattt gcttgccaaa tatagccagc agttcaaggt taaaaaagtc
    22921 atgccagctg ccttcgcgga acttcaagga gattacctgt atatgctgac aactccgagt
    22981 cgacaagaaa tggatcagat gattgctgat ttcggacaac gtcaagaata agaactatcg
    23041 gattaaggaa attcactccc ttaatccttt tgttttgtct ggtaaaaaat aagagcatcc
    23101 taacaaggta gctatcataa aacttgttcg ataactattt gaagcaggat taggtggcta
    23161 gaaattgaat tttaacattt caatttagtc atagtattgt gttttcgtat ccttaaatca
    23221 gctaaaagga tccatgacga cacctatacg atatagtttt caagatacca aacaagtcta
    23281 ttaatattca atgaaaatca aagagcaaac taggaagcta gccgcaggtt tctcaaaaca
    23341 ctgttttgag gttgtggata gaactgacag agtcagtatc atatacctac ggcaaggtga
    23401 agctgacgtg gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata
    23461 tagttaattg aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa
    23521 ctaaagaaaa gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagctgtgg
    23581 gaaattcttt ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat
    23641 ctcttattta tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt
    23701 ctagggattc cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact
    23761 tttaaaaata taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg
    23821 tttattaaaa atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa
    23881 gctatttttc aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt
    23941 tttccaacta ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc
    24001 ggagatatct atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc
    24061 cgtacacctc gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat
    24121 atcatctcag atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta
    24181 aagcgtaaga aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag
    24241 atgtttcatg gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg
    24301 ctacatggag tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa
    24361 gaagccgata aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac
    24421 aattcaacct ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt
    24481 ctttctcttt tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat
    24541 ggtgtccttt ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat
    24601 cataagcttg atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt
    24661 tcaactgcca ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt
    24721 tacgatatga aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat
    24781 gatattccag atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga
    24841 acggatcaat ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct
    24901 atcaataaat ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaggtcatc
    24961 ttaaagaaaa tcaatgattt agaaaaagaa attcaagctg gcttggctga attagaaaaa
    25021 ttactcaagt agagaggtgg ctgtatgaaa aaagtgaagt tgggggaagt cttatctcta
    25081 aaaaaaggca agaaagccac tgtacttgct gaacaaacaa ctctaagcca acgttatatt
    25141 caaatagatg atttaagaaa taataataat ttaaaattca ctgaaagttt aaatatgact
    25201 gaagcactcc cagatgatat tctgatagca tgggatggag ctaatgcagg aacagttggt
    25261 tatggattat cgggagctgt tggtagtaca attacggtct taaaaaagaa tgagcgatac
    25321 aaagaaaaaa ttatatcaga ttacttggga gtctttttgg aaagtaaatc gcagtattta
    25381 cgagaacatt caacaggtgc aacaattcct catttaaaca agaatatatt acttgattta
    25441 caattagaat tgctaggtat cgaagaacaa gagaacatta tctgtattct taatacgatt
    25501 aaaaggctta ttactaaaag aaaattgcag ttagatgaac taaacttgct cgtcaaatcc
    25561 cgatttaacg agatgtttgg ggaaaataaa atatttgaaa gcattgataa cttatttgat
    25621 attatagatg gtgatagggg caaaaattat cctaaatcag atgagttgtt tagtgaggag
    25681 tactgtttat ttttaaatac aaagaatgtt actaaaaacg gattttcatt cgatacaaag
    25741 caatttatca ctaaaacaaa ggataaatta cttcgaaaag gcaaacttga gcgttatgat
    25801 atagtcttga caacaagagg tactgttgga aatgtagcgt actacgatga attaataaaa
    25861 tataaacatt tacgtataaa ttcaggtatg gtaatattac gtcccaagac accaaatcta
    25921 aatcagaaat ttattatcca tgttttaagg aataataatt atagtcgagt gatatcagga
    25981 agtgctcagc ctcagttacc aattacaaaa ttaaaaaaaa tacttctccc cctcccccca
    26041 ctagccctcc aaaatgagtt cgcagacttt gtagcccagg tcgacaaatc acaattggca
    26101 atccaaaaat ctctggaaga acttgaaact ttgaagaaat ctctgatgca ggagtatttt
    26161 ggctgatatt ctgccattgt aattacggta atgatttgtt ataatacttc aaaggaggaa
    26221 atcagatggt agtaaaaaca agaaaacaag gaaattcaat caccattacg attccaagtg
    26281 aatttaatat tccaagtggt gttaaatacg aagcgaaatt gttaccaagt ggtgagatta
    26341 tctttactcc tgaagaattg gggcagcagg tttcttatgt atctgatgat gcctttgact
    26401 taaatttaga taaaatattt gacgaatacg acgatgtttt caaagctttg gtggaaaaat
    26461 gacaatctat ctgacagaaa agcaaattga aaaaataaat gctttagcaa ttcaacggta
    26521 ttctccaaat gagaaaattc aaacagttag ttcttctgcc ttaaatatga ttgtgaactt
    26581 accagaacaa tttgtctttg ggaagtctct ttatccaaca atttttgata aagcaacgat
    26641 actatttgtc caattgataa agaagcatgt ttttgctaat gctaataaaa gaactgcttt
    26701 cttcgttttg gtcaaatttt tacaattaaa cggctatcgt ttttctgtaa cggtagaaga
    26761 agcagtaaaa atgtgtgtaa ccatcgcagt agaagcttta actgatgaaa aaatgacaag
    26821 ctactccaaa tgggtttctg aacattctgt tagagaaaag gtcaaaaagt aacctagtat
    26881 gctggatttg aatgagcaca agaaaataaa tgaacagaca atattagaat tctgtaatgc
    26941 agaaactgat attgtctctt tttattgatg aataagaaag tgagaaatta tggaatcaaa
    27001 agttacaatt atcatgcaag aaatgttacc tcttttaaat aatgaacaat tactagcgtt
    27061 gagagagagt ttagaacatc atctagtaga cggaaaaaag cagcagaagt attcgaataa
    27121 taacctgttg caactattta ttaccgccaa gcaggtagag ggctgtagct caaaaacaat
    27181 tcgttattac cagaggacga ttgaaaactt gtttaatgct attaaagagt ctgtgacaca
    27241 actcacaaca gatgatttaa ggagttattt agcaaattac cagtctgaaa aggattgtag
    27301 taaggcaaat ttagacaata ttaggcgtat attgtcttct ttttttgctt ggcttgagca
    27361 agaggaatat atcattaaaa atcccattcg acggataaag aaaattaaga ctgagcaaaa
    27421 tgtgaaggaa acttatactg atgaacattt ggaaattatg cgtgataact gtgaaaattt
    27481 gagagatttg gcaataatag acctactagc atcgacaggt atgcgtgtag gggagcttgt
    27541 acagttgaat cgttcagata ttgattttga aaacagagag tgtgttgtct ttggtaaagg
    27601 aaagaaggag agaccagtat attttgacgc tcggacgaaa attcatttaa gaaattatct
    27661 taacgacaga aaagatagtc accctgctct ttttgtaacg ttagttggaa aagtccagag
    27721 gcttggaatt gctggtgtag agattcgctt aagaaagtta ggagacaaac tcggtataca
    27781 aaaggttcac ccacataagt tcagaagaac tttagcgact aaggcaattg ataaaggtat
    27841 gcctatcgaa caagtccaaa aactgctagg tcatagcaag attgacacaa ccctggccta
    27901 tgccatggtc aatcaaaata atgtcaagca ttcacaccaa aaattcatct cttaaaagca
    27961 aatcccgata ttccgaggag gtggttgcat gaagaaagtg aaattagggg aagtggctac
    28021 ttttatcaat ggctatgctt ttaaacctca agattggtca tctgaaggga gagagattat
    28081 cagaatacag aatctgacta aaacttcaac agagataaat tattattcgg gtacgattga
    28141 taaaaaatac attgttgaag ctggtgatat ccttatttcg tggtcgggta cattaggggt
    28201 ttttcagtgg tgtggaagat ccgcagtatt aaatcagcac atttttaaag tggtttttga
    28261 taagatagat atagataaat cgtattttaa atatgttgtt gaaaaaggtt tacaagatgc
    28321 tgtaaaacat actcatggtt ccacaatgaa acatttaact aaaaaatatt ttgataatat
    28381 tatagttcca tatacaaatt tgggagagca acaaagaatt gcaagtgagc tggatttgtt
    28441 aagcaagctg attttaagga gacaagaaca acttgaagag cttaatctac ttgtaaaatc
    28501 ccgatttaac gagatgtttg gggatgttat tctaaatgaa aaagaatgga aagttagcaa
    28561 atggaacgag attctaacaa taagaaatgg taaaaatcaa aaacaggttg aagatgctga
    28621 tgggaaattt cctatttatg gaagtggggg aattatggga tatgctaaag attggatagt
    28681 gaagaaaaat tcagttatta ttggacgtaa aggaaatata aataaaccta ttttagttag
    28741 agaaaatttt tggaatgtag atacagcatt tggattagag cctgttttag aaaaaataaa
    28801 ctcagaatat ttattctatt tttgtcaatt atacaatttt gagaagttaa ataaggctgt
    28861 aacaatacct agtttaacta aatcagattt attaaatatt tccatccccc tccccccact
    28921 agccctccaa aatgagttcg cagactttgt agtccaggtc gacaaatcac aatttgcttg
    28981 tgagatagct ataaaagtgt ggagaaatag cttgaaattt agtataatat agctaaacta
    29041 tttgtttaaa gtgagaaaaa aatgggaaat tttagctttc ttttaaaaaa tgacgaatat
    29101 gaatcttttt caaaaccttg cattgaagct gaaaatatga ttgctacatc aactgtggct
    29161 actgccttta tggcgcgtcg tgctttggag caggctgtcc attggatata tagtcacgat
    29221 tcatatttag aagctcccta tcgtgctact ctatcttctt tagtatggga tgatgatttt
    29281 agggatatcg tagattctga actccacaag cagatagttc tgttgattcg gtggggaaac
    29341 catgctgctc atggtggtga aattaaggaa cgagaagcga ttttagcttt acatcatttg
    29401 tatcagtttg ttaattttat cgattattgt tacagcaatg aatttgtgga gcgttatttt
    29461 gatgagaagt gcttaccact ttcagcaaac atcaaatacc gagaaactcc acaatctatg
    29521 ataaagttac aagacagttt accagaactg cctgattttc atgaacagat ggctgctcag
    29581 tccgtagaag ttcaagagac ttatactgaa aaacgtgaga ctgcagcgca acggcaagat
    29641 gtgcctttcc atattgaaca attatctgag gcagagacaa gaaagctctt tattgatatc
    29701 gatctccgtt tagcaggatg gatatttgaa gaaaactgtc gtgttgagat agccgttgat
    29761 ggtctcaagc acggttcagg aattggttac tgtgactacg tactttatgg taaaaatggg
    29821 aaaattttag cgattgtgga ggctaaaaaa gcctctgtca atccagaagt aggggaagta
    29881 caggtcaaag aatatgctga agctttggag aaacatatcg gctatcagcc aatttgcttt
    29941 attacaaatg ggttgaagca ctatatactt gatggtccga accgccgcca gattgcaggc
    30001 ttttactctc aagaagaatt gcaattagtg atggatagac gtcatcttca aaaaccgctt
    30061 gaggatattt ctagtaaaat tagggacgat atttccgggc gtcactacca aaaacatgcc
    30121 attgcaagcg tttgtgaagc tttctctaat catcgtagac aggcactttt ggttatggca
    30181 actggggcgg ggaaaactcg tacagcagtt tctctagttg atatcttatc acgtcataac
    30241 tgggtaaaaa acgttctctt cttagccgat agaacttcct tggttaagca agcctatgat
    30301 tcgtttagaa aattactccc agatctttcc gtttgtaact tcttagaaga taaagaagga
    30361 gctcaatcaa gtcgtatggt cttttcaact tatccgacca tgattggagc gattagtggt
    30421 caagaagaag taaatcaacg cccttttact gttgggcatt ttgaccttat cataattgac
    30481 gaatctcacc gttctattta tcagaaatac aagtccattt ttgattattt tgatgcaaga
    30541 attgtaggct taacagctac tccgcgtcaa gatttagata aaaacaccta tggattcttt
    30601 aatttggaga atggggttcc aacatatgca tatgatttgg aagaggctgt taaagacgga
    30661 tatttagtag cctatcattc tatcgaaacc aaactgaaac tacctacgga tggtctacat
    30721 tatgatgatt tgtccgaaga agaaaaggaa cattttgata gcaaatttga agacgatagc
    30781 tgtgaaaaag atattgatgg gagtgtgttt aattccttta ttttcaataa aagtacagta
    30841 gaaattgttt taaatgaact catgacaaga ggaattcaga cagcctcggg tgatgaaatt
    30901 ggtaaaacta ttatttttgc taaaaatcat gaccatgcgg aatatatcag aggtattttt
    30961 aacaaccgct atcctgaaaa agggagcgac tatgctcagg tgattgatta tagtattaag
    31021 cattatcaga ccttgattga tgattttaaa attaaggaga agtatcctca aattgcgatt
    31081 tctgtcgata tgttagatac aggtattgat gtaccagagg ttgttaattt agtcttcttc
    31141 aagaaagtac gctctaaaac taagttttgg cagatgattg gtcgaggaac ccgtctatgt
    31201 aaagatttat ttggacctga gcaggataag gaaaacttct tggtatttga ttatggggat
    31261 aattttgatt attttcgtgc agatccaaga gatggagagg gtcgtcacat tgtttcgttg
    31321 actcagcgtt tatttaatat caaagtggac ttgattcgag aacttcaggg actccaatac
    31381 caagaagatc agtttgcgag agcataccgt cagcagcttg tctcggaact tcaaggtcgt
    31441 atagagagct taaatgagtt ggacttcagg gttcgtatgg ttttagatac agtttatagc
    31501 tataggaaat tggaaagttg gcagaatcta actgctgtta caagtgaaac cattcaaaaa
    31561 aatctctctc cgcttttatt tgatgaagat aaagaagatg agatggcgag gagatttgat
    31621 ttgtggttgc ttcatattca gttggggcaa ctgacagcta aatcttccac tgttcatatt
    31681 tcccaagtga tgaagacggc tagagctctt tctgctattg gcaatatccc gcaggttttt
    31741 gagcaggctg aaattatcag gaaagtacag gagcctgaat tttggaaaga agttaacttg
    31801 tctgatttgg aaaaaattcg tcttgctatt cgagatttat tacagttttt ggataaaaca
    31861 gaccgtaaac cctactatgt taactttgaa gatcgtatac tctccactgt tcacgagacc
    31921 acagcatttt tgcaggtcaa cgatcttcgg tcttacaatg aaaaagttga gcattatttg
    31981 aaaactcatc tggatgagga gtccatttct aagctatacc ataataaaaa gttgacatct
    32041 gatgatatgc ttgcacttga aaaattgctc tgggaaaaat taggtagtaa agcagactac
    32101 caaagtcatt atgaaaataa ggcaattccg agattggttc gtgagattat tggcttagat
    32161 agagagtctg ccaatcgtat tttttctaaa tttttgtcgg atgagaatct taatgccagg
    32221 cagatttcat ttgtaaaatt gattgtagac tacattgtag aaaatggttt tttagagacg
    32281 aaagtgttaa cgcaagagcc gtttaaatct tatggttctg ttcaactact cttccaacac
    32341 caactaccag tacttcgtaa tattgttcaa atcattgaac ttatcaataa tcgagctgga
    32401 gaagcggctt aaattctaaa gtgattgcca tgctgagact catttaaaat taaaaagagt
    32461 agaaatttat gctatatatg agaagtttta ttaggaagaa tgtcatcgtt ttcctagaat
    32521 acagtatcag ttgttaagtg gttgataaat ttcaaagtag atacttgtac cacgatgttt
    32581 gttgatcgag ttattaacaa aagagctact ttgattttaa agaaatagaa aacaaaaagc
    32641 cgagcaagaa ttcaattgca ggagaaaatg aaataatact caatgaaaat caaagagcaa
    32701 actaggaaac tagctgcagg ctgctcaaaa cactgttttg aggttgcaga tggaagctga
    32761 cgcggattga agagattttc gaagagtata aatcttccta ggataaagca aaacgcatag
    32821 tatcaagggt tttcaacact tgatactatg cgttttctga tgttaaagac tttctaccag
    32881 gttttttaaa agcataattg ttagttgtag tcatttatta ttcttcaaag aaaaatggtg
    32941 gggcgaattt tttcagttct tcaaagcact tttgagcagt atctgcatct tcacagatga
    33001 taagacagac atcattacca caaagggtag cgatagcgtc agggaagctc aaagtatcaa
    33061 tgatagaacc aaaggattga gccagtccag gaagggtttt tagtaggact tggtgttgaa
    33121 ctgggcgcat ccagacaagg gcgtcttcca tgtagagttc gagacgtttt tcccattttg
    33181 agatggaacc attgttaaga acataataag cgctatcttc ttcgcggact tttgataggt
    33241 tcatattttt gatgtcgcgt gagagggttg cctgggttac ttgaatgtcg ttctcagcaa
    33301 gaagggcttg caactcagcc tgtgtatgaa tcttgttttt tgtgataaga gcgcgtataa
    33361 gttggtggcg gtgttctgat ttattcataa taatgtaact ccttttagca aggtaaggta
    33421 agcatggact gagcgaggtc gacagtcaag tggtagtctg tattgtcacg gatggtgatt
    33481 tcaaagtcag tagtatagag gactaaacgg agagtgtctc cttcttttag cttgtaaata
    33541 gttggctgca gttcaaattg aacgtccatc cattcatctg cagtaatatc ctctactaac
    33601 agtaaatcat ttctattttg taaattaagg taaccttttg tcacgactcg ttgtgcctct
    33661 ggtctaaatg gcaattcaca gagattttcc aacatgtgat agcgaccgtt gtcaatggtt
    33721 ctagcactta aaatagctgg ataaggttgt aggtatttct tttgcccaaa ttctagcagt
    33781 tgggcagata agagcccctt gtttgtactg gatttgatac gaagattgag ctgagcgcga
    33841 ccgtttaggt ggagatcttt agtcacagga aggttaatag taatctgatt ggctttccct
    33901 tgatagagct ctgtattgaa ggtttggtat gtcttaccat agcgctcaaa atccttatct
    33961 gggtactggt tttgaatagc ttgctcttct tgaccaagtg agaaggtttc acagttttct
    34021 tgcccaccga agttatcaag tgataaccaa gtctgtggag ctgtattgtc ctgccagata
    34081 acagtaggaa gttgaaagtc tgtttcctgt cctagtaatt tcttggtcaa taaggcattt
    34141 atggactcac ggaagtcaat tgattgccaa ttgttcatgt aaacatgggc accattatgg
    34201 aaaaagagat gcttgtgtat atgagtagga agagcatgga acatctggta aacatgaagt
    34261 ggtttgacat tccaatcctg agaaccatga gtaaagacaa cctctgcctt tactttatgg
    34321 gcattgagca gataattgcg gtcatgccaa aactgattgt agtccccagt ttttcggtct
    34381 agctgagctt tcactttttc taagtcagct tggtgagctt cattaccacg gatatagtcg
    34441 ccagctaaga gattacgaga ataggttaac tcagcaaggg agtcaaagtc ctcacctgga
    34501 taaccacctg ggctagtcac cagaccgttt tcacggtagt agttgtacca tgatgaaatt
    34561 cctgcctcgg caatgataac ttctaaacca tcgactcctg tagtcgcaag accattggac
    34621 atggtaccta gataggaaag tcctgttgta gcaacttttc cgtttgacca atcagccttg
    34681 acttgacgct ggcgcgtgtg atcagtaaag gcacggcaac ggccgttaag ccaatcgatg
    34741 acatttttat aagcctcgat ttgctggtag tctccattag tcatgaaacc tgtcgagtct
    34801 ttggtaccaa cacctgagac atagagattg gcaaagcctc tcggaaggaa gtagtcgttt
    34861 agtgtatagc tagagttgat gtgagttagc ttttcctcag cctctgctat aagctcagct
    34921 ttaccttggg gttggacgag atttagttga ggtttctcta gctcaatctt gtgaggaagc
    34981 ttaacctcaa gctcgccctc catcttgtag agagccttgt cactagcctt gtcattggtt
    35041 ccctgatgat aagggctggc tgtcatgatg gcagggattt ttccatcaaa acgagggcga
    35101 ataatgctaa cctttactag gtctgatagc cctttttggt cagtatcgac acgagactca
    35161 acgtaaacga cttcacgaat gacatcctgg ttagaaaaag tagccaaact cttgccgtta
    35221 aagtagtggt agtcattatc ctccggaata agaccatcac taacaagttg gtcgataaga
    35281 gtatttcctt ttttggtgcg agtattgagt aactgataga gattttcaat caagtcacca
    35341 tatataatgg gaaatccagt ttctttacga aaaacgtcac tatcttcgaa gtcaaccaaa
    35401 taagaaaagc ctaaaagttg aaaagcaaca gtataaaaaa tatctgctgt cagttcatct
    35461 tctgattgaa aaaatgtcag caggtctgtt tttttatcag ctgctaggat agaaagtggg
    35521 tagttggtgt cttgataagt gaaaaagaaa cgacgtaaaa aggtttcaag tgagtctttg
    35581 tgattggctg tattttgtaa atcaaagcca cattttttta gttcagataa gacattttct
    35641 tttggaaaat tgatataact atattgatta aaacgcatag aacctccata tagaatgaca
    35701 gttaaggtta ttatatcaaa aaaaaagcag aaagggaatt gttaacttca aaaggaaata
    35761 atccaataaa aatgaataaa gtactaaatt caatatagag aacagagtaa caataagaat
    35821 aaatagatag ggtataaaag ttctaggaga tttatattat atgctttcta tttttatata
    35881 caatatagta taaatataaa aatgatgaca aaaatacaaa tgaatagaaa ataaattagt
    35941 aagctgatga aatttttctc aagagaagcc atttataggt gaaaatggta taatatagtg
    36001 agaaggatag aggagaagtg taaattgatc gcacaactag atacaaaaac agtctatagt
    36061 tttatggaaa gcgtcatttc gatcgaaaag tatgtgagag cagctaaaga atacggctac
    36121 actcatttgg ctatgatgga tattgacaat ctttatggcg ctttcgactt tctagagatt
    36181 acaaaaaaat acggcattca tcctttgcta gggcttgaaa tgacagtgtt tgtagatgat
    36241 cagggagtga atttgcgctt tttagctcta tctagtgtgg gctatcagca gttgatgaag
    36301 ctttcgacag ccaagatgca gggggagaaa acttggtcag tcctgtccca gtacctggag
    36361 gatatcgcgg tcattgtgcc ttattttgat agagttgagt cgttagaact aggctgtgat
    36421 tactatatag gggtttatcc agaaacacta gcaagcgaat ttcatcatcc tatcttacct
    36481 ctttatcggg tcaacgcttt tgaaagcagg gatagagaag ttcttcaagt tttaacagcg
    36541 attaaagaaa atctaccgct cagagaagtt cccttgcgtt cgagacaaga tgtctttata
    36601 tcagcaagtt ctttagagaa actattccaa gagcgttttc cgcaagcttt ggacaattta
    36661 gaaaagctta tttcaggcat ttcttacgac ttggatacta gtctgaaact gcctcgtttt
    36721 aatccagcta gaccagcagt agaggagttg agagagcgtg ctgaactggg gcttgttcag
    36781 aaggggttga ctagtaaaga atatcaagat agactagacc aagaattgtc tgttattcat
    36841 gatatgggct ttgatgatta tttcttggtt gtttgggatt tgttgcgttt tggacaatcg
    36901 aatggctatt atatgggaat gggaaggggt tctgcagtag gcagtttggt ttcttatgcc
    36961 ttagacatca cggggattga cccagtagag aaaaatctga tttttgaacg ctttcttaat
    37021 cgtgaacgct ataccatgcc tgatattgat attgatatcc cagatattta tcgtccagat
    37081 tttatcagat atgttggtaa taaatatggt agtaaacatg cggcacaaat cgttactttt
    37141 tcaacctttg gagccaagca agctcttcga gatgtcttga aacgctttgg tgtgccagag
    37201 tatgaattat ctgcaattac taagaaaatc agttttcgtg acaatcttaa gtcggcctat
    37261 gagggcaatc tccagtttcg tcagcaaatc aatagtaagt tagaatacca aaaagctttt
    37321 gagattgctt gcaagataga gggctatcca aggcaaacct ctgtccatgc ggctggtgtt
    37381 gtaattagtg accaagattt aaccaactac attcctctaa agtatggtga tgaaattcca
    37441 ctgactcagt atgatgctca tggagttgag gctagcggac ttttgaagat ggactttctg
    37501 ggactacgaa atttgacctt tgtccagaag atgcaagagt tgcttgctga aacagaaggt
    37561 attcatctga aaattgaaga aatcgattta gaagacaaag aaacgttagc tttatttgcc
    37621 tctggtaata caaaaggtat ctttcaattt gagcaaccag gtgccattcg tctgcttaag
    37681 cgtgtgcaac cagtctgttt tgaagatgtc gtcgcgacta cttctctaaa tcgaccgggt
    37741 gctagtgact atatcaataa ttttgtggca agaaagcatg ggcaggaaga agtgactgtt
    37801 ctggatccag tactggagga tattttggct ccaacctacg gcataatgct ctatcaggag
    37861 caggttatgc aggttgccca gcgacttgcc ggatttagtc ttgggaaagc cgatattttg
    37921 cgtcgggcta tggggaaaaa ggatgcctct gccatgcatg agatgagggc ttcctttatt
    37981 caaggttcat tagaagctgg tcatactgtg gaaaaagcag agcaggtctt tgatgttatg
    38041 gagaagtttg caggttatgg ttttaacagg tcacacgcct atgcctactc agccttggcc
    38101 ttccagttgg cttatttcaa aacgcattat ccagccattt tttatcaggt catgttaaat
    38161 tcttccaaca gtgattactt aatagatgca cttgaagcag gttttgaagt agcctctcta
    38221 tccatcaaca ccattcccta tcacgataaa attgccaaca aggccatcta tctaggtttg
    38281 aaatccatta aaggagtcag taatgattta gctctctgga ttattgaaaa tagaccttat
    38341 tctaacattg aagattttat agctaaatta cctgagaatt atctgaaact tcctctgcta
    38401 gaacctttgg taaaagttgg tcttttcgat tcatttgaaa aaaatcgtca aaaagtattt
    38461 aataacttag ctaatctatt tgaatttgtg aaagagttgg gaagtttgtt tggagatgct
    38521 atttatagtt ggcaggaatc ggaagattgg acggaacaag aaaaatttta tatggaacaa
    38581 gagcttttag ggataggtgt cagcaaacat ccactacaag ctattgcaag taaggctatt
    38641 tacccgatta ccccaatcgg aaatttgtca gaaaatagct atgctattat cttggttgaa
    38701 gttcagaaaa taaaagtgat tcgtaccaaa aagggtgaaa atatggcctt cttacaggca
    38761 gatgatagta agaaaaaatt ggatgtcact ctcttttcag acttatatcg tcaggttgga
    38821 caggaaataa aagagggagc cttctactat gtaaaaggaa aaatacaatc acgtgatggc
    38881 cgtctgcaaa tgattgcaca agaaataaga gaagcagttg ctgaacgctt ttggatacag
    38941 gtgaaaaatc atgaatcgga tcaagaaatt tcacgcattt tagaacaatt taaaggccca
    39001 atcccagtca tcatccggta tgaagaggaa cagaaaacca tcgtttctcc ccatcatttt
    39061 gtagctaaat ccaatgaatt agaggagaaa ttgaatgaaa tcgttatgaa aacgatttat
    39121 cgctaaaaat acggaaaata gaagaatttt caacgtaaat gtggtataat cagtaagaat
    39181 gttaaaagaa aaaggagcat aaccaatatg aaacgtattg ctgttttgac tagtggtgga
    39241 gacgcccctg gtatgaacgc tgccatccgt gcagttgttc gtcaagcaat ttcagaagga
    39301 atggaagttt ttggtatcta tgacggatat gctggtatgg ttgccggtga aattcatccc
    39361 ctagatgcag cttcagtagg ggacatcatt tctcgtggtg gtactttcct tcactcagct
    39421 cgttacccag agttcgctca acttgaaggg caacttaaag ggattgagca attgaaaaaa
    39481 cacggaattg aaggtgtagt tgttatcggt ggtgacggat cttaccacgg cgctatgcgt
    39541 ttgactgaac atggcttccc agctattggt cttccaggta caatcgataa cgatatcgtt
    39601 ggtactgact ttacaatcgg ttttgacaca gcggttacta ctgccatgga cgctatcgat
    39661 aagattcgtg atacatcatc aagtcaccgt cgtacttttg taatcgaagt tatgggacgt
    39721 aacgctggtg atatcgctct ttgggctggt attgcaactg gtgctgatga aatcatcatc
    39781 cctgaagcag gcttcaagat ggaagatatc gtagcaagca tcaaagctgg ttatgaatgt
    39841 ggtaaaaaac acaatatcat cgtcttagct gaaggtgtga tgtcagcggc tgaatttggt
    39901 caaaaactta aagaagctgg agatacaagc gaccttcgtg taacagaact tggacatatt
    39961 caacgtggtg gttctccaac tgcgcgtgac cgtgttttgg cgtcacgtat gggtgcacat
    40021 gctgttaaac ttcttaaaga aggtatcggt ggtgttgcgg ttggtattcg taacgaaaaa
    40081 atggttgaaa atccaattct tggtactgca gaagaagggg cattgtttag ccttactgca
    40141 gaaggtaaga ttgtggttaa caacccacac aaagccgata ttgagctatc tagcttgaat
    40201 aagagcttgt cataatttac aatttagtta ataagaccaa aaaggtcata tatataaagg
    40261 agtcacaaaa atcatgaaca aacgtgtaaa aatcgttgca actttgggtc ctgcggtaga
    40321 aatccgtggt ggtaaaaaat tcggtgagga cggatactgg ggtgaaaaac ttgatgttga
    40381 agcttcagct aaaaacattg ctaaattgat tgaagctggt gctaacacat tccgattcaa
    40441 cttctcacac ggcgaccacc aagaacaagg tgagcgtatg gcaactgtta aacttgcgga
    40501 aaaaattgca ggtaaaaaag ttggtttcct tcttgataca aaaggacctg aaatccgtac
    40561 agaattgttc gaaggtgaag ctaaagaata ttcatacaaa actggtgaaa aaattcgtgt
    40621 tgcaactaaa caaggaatca aatcaactcg tgaagtgatt gcgttgaacg ttgctggtgc
    40681 tcttgatatc tatgatgatg ttgaagttgg tcgtcaagtt ttggttgacg atggtaaact
    40741 tggtcttcgt gtggttgcta aagatgatgc aactcgtgaa tttgaagttg aagttgaaaa
    40801 cgatggtatc atcgctaaac aaaaaggtgt gaacatccct aacactaaaa ttcctttccc
    40861 agctcttgct gaacgcgata acgacgatat ccgtttcggt cttgaacaag gtatcaactt
    40921 catcgcaatt tcattcgtac gtactgcaaa agatgtgaac gaagttcgtg caatctgtga
    40981 agaaactgga aacggacatg ttcaattgtt cgctaaaatc gaaaaccaac aaggtatcga
    41041 taacttagac gaaatcatcg aagcagctga tggtattatg attgctcgtg gtgatatggg
    41101 tatcgaagta ccgttcgaaa tggttccagt ttatcaaaaa atgattatca agaaagtcaa
    41161 tgctgcaggt aaagttgtta tcactgcaac aaacatgctt gaaacaatga ctgaaaaacc
    41221 acgtgcaact cgttcagaag tatcagacgt attcaacgct gttatcgacg gaactgacgc
    41281 tacaatgctg tcaggcgagt ctgcaaacgg taaataccca ctcgagtcag taactacaat
    41341 ggctacaatc gacaagaacg ctcaagctct tcttaatgaa tacggacgtc ttgattcaga
    41401 ttcatttgag cgtaactcta agacagaagt aatggcttct gctgttaaag atgctactag
    41461 ctcaatggat atcaaattgg ttgtaactct tactaagaca ggtcatactg cacgtttgat
    41521 ttctaaatac cgtccaaatg ctgacatctt agcattgaca tttgacgaat tgacagaacg
    41581 tggcttgatg ttgaactggg gtgttatccc aatgttgaca gatgctccat cttcaactga
    41641 cgatatgttc gaaatcgctg aacgtaaagc ggtagaagca ggtctcgttg agtcaggcga
    41701 tgatatcgtt atcgttgctg gtgtgccagt aggagaagct gttcgcacaa acacaatgcg
    41761 tatccgcaca gtacgttaag aaaaatataa aaacctatca tatccagctt tctagcctgt
    41821 atgatgggct ctttttttgt ccagggggca aaaagggggc aaaactttca taatggatt
//
LOCUS       DBEJZV010000020        40291 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.20, whole genome shotgun sequence.
ACCESSION   DBEJZV010000020 DBEJZV010000000
VERSION     DBEJZV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 40291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.20"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(56..964)
                     /locus_tag="ACL3S0_001271"
     CDS             complement(56..964)
                     /locus_tag="ACL3S0_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR1312178.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            1028..1297
                     /locus_tag="ACL3S0_001272"
     CDS             1028..1297
                     /locus_tag="ACL3S0_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGR1312179.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            1297..1677
                     /locus_tag="ACL3S0_001273"
     CDS             1297..1677
                     /locus_tag="ACL3S0_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR1312180.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            1766..1993
                     /locus_tag="ACL3S0_001274"
     CDS             1766..1993
                     /locus_tag="ACL3S0_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312181.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(2033..2758)
                     /locus_tag="ACL3S0_001275"
     CDS             complement(2033..2758)
                     /locus_tag="ACL3S0_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HGR1312182.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            2920..4761
                     /gene="typA"
                     /locus_tag="ACL3S0_001276"
     CDS             2920..4761
                     /gene="typA"
                     /locus_tag="ACL3S0_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGR1312183.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            4781..5035
                     /locus_tag="ACL3S0_001277"
     CDS             4781..5035
                     /locus_tag="ACL3S0_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGR1312184.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            5399..5698
                     /locus_tag="ACL3S0_001278"
     CDS             5399..5698
                     /locus_tag="ACL3S0_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR1312185.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            5769..7790
                     /locus_tag="ACL3S0_001279"
     CDS             5769..7790
                     /locus_tag="ACL3S0_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR1312186.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            7792..8433
                     /locus_tag="ACL3S0_001280"
     CDS             7792..8433
                     /locus_tag="ACL3S0_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312187.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLSLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            8537..9889
                     /gene="murD"
                     /locus_tag="ACL3S0_001281"
     CDS             8537..9889
                     /gene="murD"
                     /locus_tag="ACL3S0_001281"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGR1312188.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVAFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            9893..10951
                     /locus_tag="ACL3S0_001282"
     CDS             9893..10951
                     /locus_tag="ACL3S0_001282"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGR1312189.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGNKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            10961..12127
                     /gene="divIB"
                     /locus_tag="ACL3S0_001283"
     CDS             10961..12127
                     /gene="divIB"
                     /locus_tag="ACL3S0_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGR1312190.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDRESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESN"
     gene            12393..13094
                     /gene="pyrF"
                     /locus_tag="ACL3S0_001284"
     CDS             12393..13094
                     /gene="pyrF"
                     /locus_tag="ACL3S0_001284"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGR1312191.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPIIQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            13128..13760
                     /gene="pyrE"
                     /locus_tag="ACL3S0_001285"
     CDS             13128..13760
                     /gene="pyrE"
                     /locus_tag="ACL3S0_001285"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGR1312192.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMNLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            14221..14343
                     /locus_tag="ACL3S0_001286"
     CDS             14221..14343
                     /locus_tag="ACL3S0_001286"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312193.1"
                     /translation="MYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
     gene            14439..15203
                     /locus_tag="ACL3S0_001287"
     CDS             14439..15203
                     /locus_tag="ACL3S0_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312194.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVATLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVTYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            15203..15955
                     /locus_tag="ACL3S0_001288"
     CDS             15203..15955
                     /locus_tag="ACL3S0_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312195.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLGEFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            15965..16663
                     /locus_tag="ACL3S0_001289"
     CDS             15965..16663
                     /locus_tag="ACL3S0_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312196.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            16660..17307
                     /locus_tag="ACL3S0_001290"
     CDS             16660..17307
                     /locus_tag="ACL3S0_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312197.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRELSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(17387..18248)
                     /locus_tag="ACL3S0_001291"
                     /pseudo
     CDS             complement(17387..18248)
                     /locus_tag="ACL3S0_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(18260..19018)
                     /locus_tag="ACL3S0_001292"
                     /pseudo
     CDS             complement(18260..19018)
                     /locus_tag="ACL3S0_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(19019..19696)
                     /locus_tag="ACL3S0_001293"
                     /pseudo
     CDS             complement(19019..19696)
                     /locus_tag="ACL3S0_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
     gene            complement(19656..20336)
                     /locus_tag="ACL3S0_001294"
     CDS             complement(19656..20336)
                     /locus_tag="ACL3S0_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1312198.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
     gene            20551..20685
                     /locus_tag="ACL3S0_001295"
                     /pseudo
     CDS             20551..20685
                     /locus_tag="ACL3S0_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            20825..22315
                     /gene="lysS"
                     /locus_tag="ACL3S0_001296"
     CDS             20825..22315
                     /gene="lysS"
                     /locus_tag="ACL3S0_001296"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGR1312199.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            22940..24076
                     /gene="lctO"
                     /locus_tag="ACL3S0_001297"
     CDS             22940..24076
                     /gene="lctO"
                     /locus_tag="ACL3S0_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGR1312200.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPNTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      24328..24416
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            24631..25299
                     /locus_tag="ACL3S0_001298"
     CDS             24631..25299
                     /locus_tag="ACL3S0_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGR1312201.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            25542..26324
                     /gene="thiM"
                     /locus_tag="ACL3S0_001299"
     CDS             25542..26324
                     /gene="thiM"
                     /locus_tag="ACL3S0_001299"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR1312202.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVIASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            26326..26955
                     /gene="thiE"
                     /locus_tag="ACL3S0_001300"
     CDS             26326..26955
                     /gene="thiE"
                     /locus_tag="ACL3S0_001300"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR1312203.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      27164..27252
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            27513..28073
                     /locus_tag="ACL3S0_001301"
     CDS             27513..28073
                     /locus_tag="ACL3S0_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR1312204.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            28074..29459
                     /locus_tag="ACL3S0_001302"
     CDS             28074..29459
                     /locus_tag="ACL3S0_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1312205.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREINQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            29461..30111
                     /locus_tag="ACL3S0_001303"
     CDS             29461..30111
                     /locus_tag="ACL3S0_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGR1312206.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            30122..30814
                     /gene="tenA"
                     /locus_tag="ACL3S0_001304"
     CDS             30122..30814
                     /gene="tenA"
                     /locus_tag="ACL3S0_001304"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGR1312207.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            30819..31343
                     /gene="thiW"
                     /locus_tag="ACL3S0_001305"
     CDS             30819..31343
                     /gene="thiW"
                     /locus_tag="ACL3S0_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGR1312208.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            31343..32146
                     /locus_tag="ACL3S0_001306"
     CDS             31343..32146
                     /locus_tag="ACL3S0_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR1312209.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            32139..32771
                     /gene="thiE"
                     /locus_tag="ACL3S0_001307"
     CDS             32139..32771
                     /gene="thiE"
                     /locus_tag="ACL3S0_001307"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR1312210.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(32980..33771)
                     /gene="thiD"
                     /locus_tag="ACL3S0_001308"
     CDS             complement(32980..33771)
                     /gene="thiD"
                     /locus_tag="ACL3S0_001308"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR1312211.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(33855..33953)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            34137..34532
                     /locus_tag="ACL3S0_001309"
     CDS             34137..34532
                     /locus_tag="ACL3S0_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGR1312212.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            34543..34914
                     /locus_tag="ACL3S0_001310"
     CDS             34543..34914
                     /locus_tag="ACL3S0_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGR1312213.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            34924..37167
                     /locus_tag="ACL3S0_001311"
     CDS             34924..37167
                     /locus_tag="ACL3S0_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR1312214.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRVNGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            37374..39149
                     /gene="spxB"
                     /locus_tag="ACL3S0_001312"
     CDS             37374..39149
                     /gene="spxB"
                     /locus_tag="ACL3S0_001312"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGR1312215.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            39260..39607
                     /locus_tag="ACL3S0_001313"
     CDS             39260..39607
                     /locus_tag="ACL3S0_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR1312216.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(39724..>40291)
                     /locus_tag="ACL3S0_001314"
     CDS             complement(39724..>40291)
                     /locus_tag="ACL3S0_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR1312217.1"
                     /translation="FKKTRKRFKYSRRFHKVRLMYQDEAGFGRISKLGSCWSPIGVGP
                     HVHSHYIREFRYYYGAVDAYTGESFFLRAGGCNTEWMNVFLEELSQAYPDDYFLLVMD
                     NAIWHKSSTLKILTNIGFAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRTLEDVMNQL
                     QDVIQGLEKEVIKSIVNQRWTRMLFESR"
BASE COUNT        12022 a         7287 c         8763 g        12219 t
ORIGIN      
        1 aaaaagaacc aatgtgcagg ttgttgctag cctacatatt ggttcttatc atttctcaac
       61 tatcaaactg aacttcttct agtagatagt caataaagcg ttcgcccatc ttagataggc
      121 tggttttctc atgctggata tagaccagct caatcgggtc atcaatatcc agtgggatag
      181 aaacgatatt gtctccgttt aggttgctgt tcaaaatccc tgtcgcaatg gtataaccat
      241 ccaaaccaat caagagatta aagagggtgg cacggtcact gaccacaatg gatttcttgt
      301 ggtgttcttg agaaagaatc tcttctgaaa agtagaagga gttgtgcgtc ccttggtcat
      361 agctgaggta agggaaattc tccaaatcag acagtttcac cttgtctttc tttgccagag
      421 ggttggtctt gctgacaaag atatgcggtt gcgctgtgaa gagatggtgg gctagcaggt
      481 gattgtcatc cagcatcttg gttaaaacat cacggttgta actgtttaag aagaggaccc
      541 cgacctcact gcggaagttc ttgacgtcgt cgataatctc ccaagtccga gtttcacgaa
      601 ggaagagttc gtatttctcc atatcgcttt tcttgagcaa agagacaaag gcattgacca
      661 caaaggcata gtgttgagac gaaacgctaa agagttcgcg gtgggcaaca ggatttttat
      721 agcgttcctc cagaagctgg gtctgctcga caacctgacg ggcataagag agaaactcca
      781 tcccatcacg ggtcaaggta atacccttgg gattgcggat aaagatttca atgcccattt
      841 cattttccaa atctcgcact gcattggaga gactgggctg agtgataaag agttgcttgg
      901 ctgcctcatt catagagcca gtttcgacga ttttgataat ataatgtaat tgttgaattc
      961 tcatgttttt attgtaccac acttgcctta gaatcgccaa agaagatagg aaaataagga
     1021 gcattgtgtg agtctcttct tgaaaaaaac acaaaatttt gctagaatga gtcttatgaa
     1081 aacattctat gatgtgcagc aattcctcaa acgatttggt attattgttt acatgggaaa
     1141 acgcttatat gatattgaac tgatgaagtt ggaactatct cggatttacg atgcagggtt
     1201 gatggataaa ttagactatc tagaggcaga agcagttctt cgcagagagc acaaggtaga
     1261 attggattat attgagaaaa atggagaaaa gaactaatgg ttacttggat tttgtgggca
     1321 cttatactag caatgttggc gtggatgggc tttaactatc ttcgtattcg tcgtgcggct
     1381 aaaattgtgg acaatgagga gtttgaagcc ttgattcgta cgggtcaatt gattgatttg
     1441 cgcgacccag cagaattcca cagaaaacat atccttggtg cacgcaatat tccttcaagt
     1501 cagttgaaaa ctagtcttgc agcccttcgt aaagataaac ctgtccttct ctacgagaac
     1561 caacgtgcgc aacgagttac aaatgcagct ctttacttga aaaaacaagg tttttctgag
     1621 atttatatcc tttcttatgg cttggattct tggaaaggga aagtgaagac tagctaacct
     1681 tatttccaaa ttagtcgaat gataggatga agctattgtt ttatagtata attaatttgt
     1741 ataaaattta aggagttctt agaacataaa agaaaagaag aaaaatccac tttttgtggg
     1801 tatcttgtcg attattcttg gtttgttatt tccaattgta ggcctgattt tgggtatcat
     1861 aggattggtc ttggctattt cataccaaaa agagtcacaa ttagactata aaatagaaaa
     1921 gattcttaat atcttaggaa ttgtgatttc tgtagttaac tggattgtag caatcgcctt
     1981 aatttttcgg taaataaaag aaaaaagctt tagttttaaa gcttttttta ttttatcgac
     2041 tcatctctaa atagttttta atgatttgta actctttttg gttcaaaggg cggtagttac
     2101 cttctgctaa atctgggttc aatgtgaagt ccccaaattg gattctcttg aggctagtta
     2161 ccttaacacc aaccgagagg aacattttct tgatttgatg aaattttcct tctgaaatgg
     2221 tgatagaggc ttgactgagg gaaggacttg cagatagaat ctctagtttt gcgggtttac
     2281 agacagtacc atctaaaaag acaattccct tttgaaaggc ttggatatgg tcaggtgtta
     2341 gaagtccatt aacctcaact tgataagtct tatcgacatg atattgggga tggaggagtt
     2401 ggaagcccaa gggaccgtta tcggtcaaga gaaggagtcc tgttgtatct cggtccagtc
     2461 ggccgacggc atagagcttg tcagactgga tgtcagatgg aagcaggtcc atgacggtcg
     2521 gaagttcctt gtctttgttg gctgtaacga caccagcagg tttatgaagc ataagatagg
     2581 tgtgttcata gccttgaatg attcgatcct gaaaaaggag ttcttgtagt cctgtatcga
     2641 tattttgagc tagggagcgg gctgggcaac catcgactag aatttcccct ctgaggagtg
     2701 cttgcttcat ggcctttcgg ctaacttttt cttgggctaa taaattatct aaacgcatac
     2761 tgtgcctatc ttatcataag tcgcttgctt tgaaaaggct tgacgtgaaa agaaaagcgg
     2821 agtgaaaaca tttacacttg cttgagttat gttatttatt tgaaattatg gtataatcgt
     2881 tcagttagaa aataaatttt gaatattata gaggaaatca tgacaaaatt aagagaagat
     2941 atccgtaaca ttgcgattat cgcccacgtt gaccacggta aaacaaccct ggttgacgaa
     3001 ttattgaaac aatcagaaac gcttgatgca cgtactgaat tggcagagcg tgctatggac
     3061 tcaaacgata tcgaaaaaga gcgtgggatt accatccttg ctaaaaatac tgccgttgct
     3121 tacaacggaa ctcgtatcaa cattatggac acaccaggac acgcggactt cggtggagaa
     3181 gttgagcgta tcatgaaaat ggttgacggt gttgtcttgg tcgtagatgc ctatgaagga
     3241 accatgccac aaactcgttt cgtattgaaa aaagccttgg aacaagacct tgtcccaatc
     3301 gtggttgtta acaaaatcga taagccatca gctcgtccag cagaagtagt ggatgaagtc
     3361 ttggaacttt tcatcgagct tggtgcagat gacgaccagc ttgatttccc agtggtttat
     3421 gcttcagcga tcaacggaac ttcttcattg tcagatgatc cagctgacca agaagcgact
     3481 atggcaccaa tctttgacac gattatcgac catatcccag ctccagtaga taactcagat
     3541 gagcctttgc agttccaagt gtcacttttg gactacaatg actttgttgg acgtatcggt
     3601 atcggtcgtg tcttccgtgg tacagttaag gttggggacc aggttaccct ttctaaactt
     3661 gacggtacaa ctaaaaactt ccgtgttaca aaactcttcg gtttctttgg tttggaacgt
     3721 cgtgaaatcc aagaagccaa agcgggtgac ttgattgccg tttcaggtat ggaagacatc
     3781 tttgtcggtg aaaccatcac tccgacagat gcagtagaag ctcttccaat cctacacatc
     3841 gatgagccaa ctcttcaaat gactttcttg gtcaacaact caccatttgc tggtaaagaa
     3901 ggtaaatggg taacttctcg taaggtggaa gaacgcttgc aggcagaatt gcaaacagac
     3961 gtttcccttc gtgttgaccc aactgattca ccagataaat ggactgtttc aggacgtgga
     4021 gaattgcact tgtcaatcct tatcgaaaca atgcgtcgtg agggctatga acttcaagta
     4081 tctcgtccag aagttatcgt aaaagaaatc gacggtgtta aatgtgaacc atttgaacgt
     4141 gtacaaatcg acactccaga agaataccaa gggtctgtta tccaaagcct ttctgaacgt
     4201 aaaggtgaaa tgttggatat gatttcaact ggtaatggtc aaactcgttt ggtcttcctt
     4261 gttccagcgc gtggtttgat tggatactca actgagttct tgtcaatgac tcgtggttac
     4321 ggtatcatga accatacctt cgaccaatac ttgccattga ttccagggga aattggtgga
     4381 cgtcaccgtg gtgcccttgt ttctatcgat gctggtaagg ctacaactta ctcaatcatg
     4441 tctatcgaag aacgtggtac gatctttgtc aacccaggta ctgaggttta tgaaggaatg
     4501 atcatcggtg aaaactctcg tgaaaatgac ttgacagtta acatcacgaa ggcaaaacaa
     4561 atgaccaacg ttcgttcagc tactaaggac caaacagctg ttatcaagac gcctcgtatc
     4621 ttgacacttg aagagtctct tgagttcttg aacgacgatg agtacatgga agtaacgcct
     4681 gagtctatcc gtttgcgtaa acaaatcctt aacaaagcag agcgtgagaa agctaacaag
     4741 aagaaaaaat cagctgaata agagctagaa agagagaaag atggtctatt tagtcctagg
     4801 aattttactg ctcctactct atgtatttgc gacaccagaa agcattaaag ggactgtcaa
     4861 tatcgtcgct atggtatgta ttttagtggc actcttgatt ttattggttc tatcttttct
     4921 gaaaattttt caattaccaa cagaaatatt cctagcaata gccatgttga tcctagctta
     4981 ctttagtgtt agagacatca cactcatgcc agtcaaaaaa agtaaaagaa gataaaaaga
     5041 gagttttggc tctctttttt gctaggaatt ttacaagatt gcaatttatt tttgagttat
     5101 caccatctct tttgtttgga taatatgaat gggaaaaact tgaataaaat tctttaatgg
     5161 catctatttt atatttggtt agtactggtt gcatattatt ttgaaataaa actactatat
     5221 aatattattc atagaggcaa tgtagtaaaa tatctaaaaa attcgatttt ttccttgaca
     5281 acaaataata aaaatgatat ttttatcaca taagaaagcg gtttcaacaa aagagagagg
     5341 agggtttatt ttgttgcatt gttgctcaag gtgtgctttt tttgaaagaa aaaataaaat
     5401 gaaaacgaaa aaacatagat tacttgctct agctcttatt tcaagtttta cattattggg
     5461 agctgcatca gctgctgtac aatatccaga tggaggagta tggacgtatg gagaaggttc
     5521 aggaggtggt tgggcttttt caaattacta tcatggtaaa aaatatcatt attcttctct
     5581 tgtaagtaga tggaatagtc attcagataa aggagaagct tctgctggaa aaacctccta
     5641 tgcatggatt tggactaaat ggggagaaca agtagcattt tactgtgatt atgactaatc
     5701 gttcattgat ttaaatcgtt ccccttgtaa gaaattacag ggggaatttt gtttacaagg
     5761 agtctactat gaagaaacta ttcatattat tatcaacttt ttttctcagc ttcttccttg
     5821 cttggattat tgtcttacgt gcgccacaat atttatatgc aagctatgat tccgtttctt
     5881 tacttcgtgt caaaaaagat actcaggaac cgacgcgtga ggtatttgaa caggaattgg
     5941 agaattttgc aaactcagaa cagagtttaa tagctagaag aattgtagag ccgagtaagg
     6001 atgggacgac tcactttact tatgcaactt atggtcaggg aactttacca aaagaattcc
     6061 aagaagctag ccaagaaagt cgtgaacgta gtgatccgct aaatagttat ctccttttgt
     6121 caggctcctt gacgaaagaa aagcttgccg ataaattagg agatttgggt tataaagcaa
     6181 gtgctgaccg aaagataccg ccctattttc ttgcttttcg aatattacta aatcccctta
     6241 ttttaattag tttagcaata tttggcttat ctttctttgc tttagtgatt atcactcgga
     6301 ttaaggaaat gagagcagca ggtataaaac tcttttctgg tcagactctc ttatccatca
     6361 tggggcattc tttatctact gatatcaaat ggctccttct atcagccctc ctttccttcc
     6421 taggtggggg agtcgttctt tttagtcaag gtttgtttta tcctatcttg ttagccacct
     6481 atggttttgg gattagtttc tatctgttgt ttttattggc gatttcaatt ttactaatgc
     6541 ttctttatct aatgagtttg agttacaaag cattagttcc cgttattaag gggagattac
     6601 cccttaaacg cctgatgatt ttaaccctat tgtgtcagtt ggttgctgtc tttacagtag
     6661 gctacgctgt taagacaggt ttgatgtctt accaacgatt gaaagaactt gaaatttcaa
     6721 aacaagcatg gcaggataga gcagactatt atcaaatttc ttttggctta ggtgatagag
     6781 gaaaagatac agaaaatcag agcaagtggt atgcctttgc caaggaagca atcgaagaag
     6841 aacaagctct ttatgtaaag gataatctgc tccattttgc caatccacaa ggaaaaaatg
     6901 aacagggaga gacactggat acctatagtc cagatgctaa tacgctctat gttagtccca
     6961 gttatttgga caaggaaaag gtcgtggtag atgctgagac caaacagaag ttagcccatc
     7021 tccaaaaagg tgagtttatc ctcttgctcc cagaacattt gcgctctcga gaagcagaac
     7081 ttaagaaagt ttttgaagaa agattgagtt attatggaaa atctggtgag gaggcaagtg
     7141 ctcctttgga ttatgagatg aaagcgcacg ttagttatct ttcaatggga gaaaagcggt
     7201 ttgtttataa taacggtgag aatcccgtat ccactcagta tttgactgat ccgattttag
     7261 tggtattcac gccgacttct acaggtgata gttttatatc cttatctagt tggtctatca
     7321 atgctggaaa acaactcttt atcaaaggat atgagagtgg gctagaactc ttgaagaaag
     7381 ctggaattta tgagcaagta tcctatctta aagaaggaag aagtgtttat ctaactcgtt
     7441 ataatgaagt tcaaactgaa acagcaactt taatcttagg agctattgtg gggatagcta
     7501 gttccttgtt actattttat tctgtcaatc ttctatattt cgagcaattc cgccgagata
     7561 tcttgattaa acgaatttca ggtttacgat tttttgaaac acatgctcag tatatggtta
     7621 gccaatttgc cagttttgta tttggtgcta gtctctttat tttaagcagt cgagacttgg
     7681 tgattggctt gctcacttta ttggtctttc tagctagtgc agttttgacg ctttaccgtc
     7741 aagcgcagaa agaatctcgt gtttctatga caattatgaa aggaaaatag gatgattgaa
     7801 ctaaagaata tatctaaaaa atttggaagc cgtcagctat tttcagatac gaatcttcat
     7861 tttgaaggtg ggaaaattta tgccttaatc ggtacaagtg gctgtggtaa gacaacactc
     7921 ttgaatatga ttggacgatt ggagccatat gacaaagggc aaatcatcta tgatggcact
     7981 tctcttaagg acatcaagcc ttctgttttc tttagagatt acttaggata cttatttcaa
     8041 gattttggct taattgaaag ccaaaccgtc aaagagaatc tcaatctgag tttagttggt
     8101 aaaaagttga aggaaaaaga gaaaatctct ttgatgaaac aagctctaaa ctgtgtaaac
     8161 ctctcttatt tggatttgaa gcaacctata tttgagttat caggaggaga agcacaacgt
     8221 gttgcactag cgaagataat tttaaaggat ccgcctttga ttcttgcaga tgaaccaacc
     8281 gcttccttag accccaaaaa ttctgaggaa ttactttcca tcctagaatc tttaaaaaat
     8341 ccgaatcgga ccattattat tgcgacccac aatcctctga tttgggagca agtggatcag
     8401 gtcattcgag ttaccgattt atcacataga tgatatggta agattcagtt agaagaaaga
     8461 gtcacaaaca cactttgtgg cttttttatt tccataaaaa tggtaaaata gtaggagtag
     8521 aaatggagtt cgagacatga aagtaataga tcaatttaaa aataagaaag ttcttgtttt
     8581 aggtttggcc aagtctggtg aatctgcggc tcgtttgttg gacaagttag gtgccattgt
     8641 gacagtaaat gatgggaaac cattcgagga caatccagct gcccaatgtt tgctggaaga
     8701 agggatcaag gtcattacag gtggccatcc tttggaactc ttggatgaag agtttgccct
     8761 tatggtgaaa aatccaggta tcccctacaa caatcccatg attgaaaagg ctttggccaa
     8821 gggaattcca gtcttgactg aggtggaatt ggcttatttg atttcagaag caccgattat
     8881 tggtatcaca ggatcgaacg gtaagacaac cacaacgact atgattgggg aagttttgac
     8941 tgctgccggg caacatggtc ttttatcagg gaatatcggc tatccagcta gtcaagtggc
     9001 ccaaactgcg tcggacaagg acacgcttgt tatggaactt tcttctttcc aactcatggg
     9061 tgttcaagaa tttcatccag agattgcggt tattaccaac ctcatgccaa ctcatatcga
     9121 ctaccatggg tcattttcgg aatatgtagc agccaagtgg aatatccaga acaagatgac
     9181 agcagctgat ttccttgtct tgaactttaa tcaagacttg gcaaaagact tgacttccaa
     9241 gacagaagcc actgttgtag cattttcaac acttgaaaag gttgatggag cttatctgga
     9301 agatggtcaa ctctacttcc gtggtgaagt agtcatggca gcgaatgaaa tcggtgttcc
     9361 aggtagccac aatgtggaaa atgcccttgc gactattgct gtagccaagc ttcgtgatgt
     9421 ggacaatcaa accatcaagg aaactctttc agccttcggt ggtgtcaaac accgtctcca
     9481 gtttgtggat gacatcaagg gtgttaaatt ctataacgac agtaaatcaa ctaatatctt
     9541 ggctactcaa aaagccttgt caggatttga caacagcaag gtcgtcttga ttgcaggtgg
     9601 tttggaccgt ggcaatgagt ttgacgaatt ggtgccagac attactggac tcaagaagat
     9661 ggtcatcctg ggtcaatctg cagaacgtgt caaacgggca gcagacaagg ctggtgtcgc
     9721 ttatgtggag gcgacagata ttgcagatgc gacccgcaag gcctatgagc ttgcgactca
     9781 aggagatgtg gttcttctta gtcctgccaa tgccagctgg gatatgtatg ctaactttga
     9841 agtacgtggc gacctcttta tcgacacagt agcggagtta aaagaataaa atatgaaaaa
     9901 aattgtcttt acaggtgggg ggacggttgg acacgttacc ctcaatcttt tgttaatgcc
     9961 caagttcatc gaagatggtt gggaagtcca ctatatcggg aacaagcgtg gtatcgaaca
    10021 ccaagaaatc cttaagtcag gtttggatgt cactttccac tccattgcga ctgggaaatt
    10081 gcgtcgctat ttctcttggc aaaatatgct ggacgtcttc aaagttggct ggggaatcgt
    10141 ccaatcgctc tttatcatgt tgcgacttcg tccacagacc cttttttcaa agggaggctt
    10201 tgtctcagta ccgcctgtta tcgctgcgcg tgtgtcagga gtgcctgtct ttattcacga
    10261 atctgacctg tctatgggct tggccaataa aatcgcctat aaatttgcga ctaagatgta
    10321 ttcaaccttt gaacaagctt cgagtttggc taaggtcgag catgtgggag cggtgaccaa
    10381 ggtttcggac aaaaacactc cagaaccaga tgaattggtg gatattcaaa cccactttaa
    10441 tcccaaattg ccaactgtat tgtttgtcgg cggttctgca ggcgctcgtg tctttaacca
    10501 attggtgaca gaccataaga aagaactaac agagcgctac aatattatca atctaactgg
    10561 agattctagt ctgaatgagt tgaggcaaaa tctttttcgt gttgactatg tgaccgatct
    10621 ctatcaaccc ttgatggaat tggctgatat tgttgtgaca cgaggtggtg ccaatacgat
    10681 ttttgagctc ttggcgatag caaaattgca tgtcattgtt ccgcttggtc gtgaagctag
    10741 tcgtggtgac cagattgaaa atgcagctta ctttgtaaaa aaaggctatg cagaagacct
    10801 tcaagaaagc gatttgacct tggatagttt ggaagagaag ctttctcact tactaagtca
    10861 caaggaagat taccaagcta agatgaaagc ttctaaggaa ttgaaatctc tagcagattt
    10921 ttatcaattg ttgaaaaaag atttatcata aggaaagtaa atgtcaaaag ataagaaaaa
    10981 tgaggacaaa gaaaccctcg aagaattgaa agagttatca gaatggcaga aacgaaacca
    11041 agaatatcta aaaaagaagg ctgaagaaga ggcggctcta gctgaggaga aggaaaagga
    11101 aagacaagct cgaatgggag aagaatctga gaagtcagag gataaacagg accgggagag
    11161 tgaaacagac caggaagatt cagaatcagc taaggaagag tctgaagaaa aagtagcatc
    11221 ctcagaggct gacaaagaga aagaagagaa agaagaacca gagtctaaag agaaggagga
    11281 acaggataaa aagctttcta aaaaggctac aaaggaaaaa ccagccaaag caaagattcc
    11341 tggtatccat atcttgcgag ccttcacgat tttatttcca agtctgcttt tattgattgt
    11401 ctctgcctac ttgctcagtc cttatgcgac catgaaagat attcgtgttg agggaacagt
    11461 gcaaactaca gctgatgata ttcgacaggc ttcaggcatt caggattcgg attatacgat
    11521 taatcttctg ctagacaagg caaaatatga aaagcagatt aagtctaact attgggttga
    11581 atcagctcaa cttgtctatc aatttccaac taagttcact attaaggtca aggaatatga
    11641 tattgtggcc tactatattt ctggtgaaaa tcattatcct attctttcca gtggtcagct
    11701 tgagactagt tctgtgagtc tgaacagttt accagaaact tatttatcag ttctctttaa
    11761 tgatagtgaa caaatcaagg tttttgtctc agaacttgct caaattagcc cagaactcaa
    11821 ggcggctatc caaaaggtgg aattagcccc aagcaaggtg acatccgatt taattcgatt
    11881 gaccatgaat gattcggacg aagtcttggt tcctctatct gaaatgagta agaaactgcc
    11941 atattacagt aagattaagc cacaattgtc agaaccgagt gtggtcgaca tggaagctgg
    12001 aatttacagt tacactgtgg cggataaatt aattatggag gctgaggaaa aagccaaaca
    12061 agaggccaag gaagccgaga aaaaacagga agaagaacag aaaaaacaag aggaagagag
    12121 caattgaaat caaacgaccc agcgctcatc gcgtcgctag gtttaccttt tctcttatag
    12181 ttctttagtg accatgtttt tacttgacaa gtgctagtag aaataataga ataatagaaa
    12241 acctttaaag cagtccagag aggcagctaa ggttagacgg tgaaagggtg gagactaccc
    12301 atttttcgtg gaaccttgct gttggcaggt tccttttttc gtggcttctg ttggccagac
    12361 tctctcacta gtaaaggtaa aaggagaaac ctatgcgaga acatcgtcca atcattgctc
    12421 ttgattttcc tagttttgag gcggtcaagg aatttttagc tcttttccca gcagaagaaa
    12481 gcctttatct caaggtaggg atggagcttt attacgcagc ggggcctgag attgtgtcct
    12541 acttaaaagg tttgggtcat agtgtctttt tggatctcaa acttcatgac attcctaata
    12601 cagtcaagtc agcaatgaag atcctatctc agcttggtgt cgatatgacc aatgttcatg
    12661 cggctggtgg tgtagagatg atgaaggctg cgcgtgaagg tcttggaagt caagctaaat
    12721 tgatcgctgt aactcagctc acatcaacgt cagaagctca gatgcaggag tttcaaaata
    12781 tccaaaccag tctgcaagag tctgtgattc actatgccaa gaagacagct gaagctggct
    12841 tggatggtgt tgtttgctcg gctcaggaag tacaagtcat caagcaggct accaatccag
    12901 attttatctg tctgacacca gggattcgtc cagctggtgt tgcagttgga gatcaaaaac
    12961 gagtcatgac acctgctgat gcctatcaaa tcggcagtga ctatatcgta gtgggacgtc
    13021 ccattatcca agctgaggat cctgttgcag cttatcatac catcaaggat gaatggacac
    13081 aggactggaa ttaaagaact agattagaaa aataaaagga gaataccatg acacttgcta
    13141 aagatatcgc tagccacctc ttgaaaatcc aagccgttta cctcaaacca gaggaaccct
    13201 tcacttgggc atctggtatc aagtcaccga tttacactga taatcgtgtg acactagcct
    13261 atccagaaac tcgtacccta attgaaaatg gttttgtgga tgctatcaaa gaagcctttc
    13321 ctgaagtaga agtgattgca ggaactgcaa cagcagggat tccacacgga gccattattg
    13381 ctgataagat gaacttgcct tttgcctaca tccgtagcaa accaaaagac cacggagctg
    13441 gtaatcaaat cgaaggtcgc gtagctcaag gtcaaaaaat ggtagtggtt gaagacctta
    13501 tttcaacggg tggttcagtt cttgaagctg tagcagcagc caagcgagaa ggagcagatg
    13561 tacttggagt tgtagcgatt ttcagctacc aattgccaaa agcagataag aactttgcag
    13621 atgctggtgt taaacttgtg acgctttcaa actatagcga gcttatccat ctagcccaag
    13681 aagaaggtta catcacgcca gagggccttg atcttctaaa acgctttaaa gaagaccaag
    13741 aaaattggca agaaggttag gtcagtaaga taaagagaga cgaggctacc gagcctcttt
    13801 taccatttta tttaaaatat gacaatattt taaataaaat aattgacaac gctttctttt
    13861 attgatataa tgaaaatgta atatgtatca aattgatcaa tcaactatct tgtttatcac
    13921 ttcttaagag gacgatgtca tgaaaagaag aaaaatatat tccttttttg cgtagttaca
    13981 attgcatcta gtttgtttct ccctacagtt ttagctagac agattggaaa ttatgattta
    14041 acgttgccgc gttggggttc ggatacaact agtgagcttg agaaagaaaa cgcctctgct
    14101 ggaattaata atagtgacag cactggtggc ggtaaaaggt taagtacctc tattcgtagc
    14161 gcctatagtg ggtcagatat taccccggta tattcattgg ggtctggctc taggattgtc
    14221 atgtactata atggaggtgg tgacaattat attggttctg gtactagatt agctatggcg
    14281 ccacaatttg gaaatcatgt aagaattcat acttcaggtt cttggagtcc agattcttat
    14341 taacttactt gtcagagtaa gccttaaaga tggttgattg tgggtgtagc atgaaaaaag
    14401 aatgctacac cctattttta ttataaggag gagtaaggat ggaatttttc atttgtaatc
    14461 ttgtacgagt cgttcaatca cctcgatttt atatgtcttt atttttgacc cttctttgca
    14521 tgagtttagg aaatttcctt gctttcaatg gtatttataa aattgaaggt ttatcgattt
    14581 tttttgccgc ttcttctatt cgaggatttt caccgattag cctagtagct gcacttatct
    14641 gtacactgcc ctattctagt cagataatag aggatgctga gagtcatttt ctaacagcac
    14701 aattgtgccg aatttctaaa aagaggtatc tagctattgt aggtagtact gcaattattt
    14761 cttcttttct agtctttttt ctcccctatt tattattatt aggaattaat cttttagtga
    14821 ctccttatca ggaaatttat attggagatt atagtggtgc cttaaaagaa ttatttgatt
    14881 ctaatcagtt gctctatagt cttgtggcga ctctttggta tggagtttgg ggcgctgtgt
    14941 tctctatttt tggactagct agtgctttgc tagtgaagaa aaaaatagga gctattttca
    15001 tcccagttac ctatatgatg gttggtggta ttttttgggc tattttaggg ctatcttact
    15061 tagaacctgt gacaacatta gctttgggat atcagaaaga tatcagtctt tccttagtta
    15121 gtgggcatct tgcttttatt ttatttgtta gttgtttggt tgtttatggt acattttttc
    15181 tacattcaga ggactatgta taatgaaaca atttgttcaa ttttataaaa aagatttctt
    15241 agcagtattg gtttatttta tattactgct atcctgtgtt ttatctagta cagtatattt
    15301 attgcgctgt cgccaatatt caatccatcc aaatgtatta gaatggattt tagttttact
    15361 tcaagatatg acgactggag tatattgctt tccgttcaca tatatattgt tcttttttta
    15421 tttgatgaat aactatttta ataggttgga gtgtcgcatt cgtctgaaat caattaagca
    15481 ctttaccagt tttagtttca aattagcagc tcttagtacg gggatttgga cggcgacttt
    15541 atttttattg atttttctaa ttgcatttag taatggtttt agcttctctt tggagataaa
    15601 ggaggttgat tttttaggag aattttatgg tataagtatt gcaaacaatg ctagtttctt
    15661 tataggattt tttttctctt atatagcata ctatttcttt ttatccttac ttactattag
    15721 cagtttttct tggtttaaaa aatcaaacat gagcttagta tttctgttta cttttttatt
    15781 tgtagaatcc ttattctgga tttatcagtt gaacaatggg ataattggat tattgccaat
    15841 ttttcagtat atggtaaatt ccaatccgta tgcattgatt tattggctta cattactatc
    15901 tatcataatt ccattgactg tattttctgt tcatagaaac tggaggagag tgtaaaagtt
    15961 ggaaatggga aagttaagta gtcacatgtg gaggttgaat cagataatct ataccaagta
    16021 cttttggggt tatgttcttt tttggatatt gatttgttta ggattatggt attggttaga
    16081 aggaaatgat agacttgtta tagaaatttt aaaagggcct aatctgagtc aaaactcttt
    16141 tttagtctta tctatatggt tgcttcattg gtttattatt catacatttt ttctagcagt
    16201 tgtatatcgt agaagagcat ccgatttctt tatggaagtg attcgatttt cttctattaa
    16261 gctctggatt aggtatcaga tttggacctg ttttctttat ggactcattt taatcatggt
    16321 aaaagttcta gtgattcaat ttatgttaca gttagcaaac tgggatatag gagttttgtt
    16381 tatagttgat tctttgaatg cttgtgtgct atccttgctt tgctttatgt tatacgcact
    16441 aggagcgaat gtacaaatga actttgcttg cgttagtttc tttttactca tgattgtgtt
    16501 tggtggtcta tttgtaggaa atcgaactaa ttatctattt tatattttga atcgagggaa
    16561 tggagatata ggacgagatt tatttcttca gttgctattt ttagtctttc tttttaaaag
    16621 cattttctat ttcactcgtc aaaagaggag gtttatagaa tgaatgaaat aattacatta
    16681 aaaaatattg agttgaaatt aaaaaaaaca tgtgtttttc aaaaccttaa ttttagttgt
    16741 aaacaggggg aaattatagg aattactggt gcgaatggct caggtaaaag tgtattgttt
    16801 aaattaatag ctggtttata tagtccgtct tatggagaag tgttaatcaa tggggaaaat
    16861 attgttcctg agagaaaaat tccagctaat ttgggagctt tgattgaaga acctggtttt
    16921 ataaattatt atagtggctt taagaattta caatatttgg caagcatacg aggagtagtt
    16981 ggtaatcagg aaatcaatga tacactgaaa atagttggtc tatatgagca aaaagaccag
    17041 aaagttaaaa cttattcgct aggtatgagg aaaaagctag ggattgctca agcaattatg
    17101 gagaatccct ctattctttt actagatgaa cctatgaatg ccttggataa atcaagtgta
    17161 gaaaatatga gaacattgtt tagagagctc tctagtgaaa aagggacaac aattttgatt
    17221 gctagtcata gtgaagagga tattcgtatc ttatgtgata aagtatatgc aatagaagat
    17281 aaagtatgta cactgtgttc agattgaaca tcttagatag actcaggatg ttataggtaa
    17341 aatcttaaaa agggattgga gcttaaaatc cagtcccttt taagagttaa tggccacctt
    17401 caacaaccag gtcatctgct ttagcagcgt caccgtaggt tgggtgaagt gttttttcat
    17461 aggccttgtg gaagaagttt tccttgccta atttttcaat atctttattg atgaagtcta
    17521 gcaattcttg gttgtctttt tgaactgctg ccgcaatggt atcgggatca ccgagggaag
    17581 taattcctac ttcaaatcct ttattttcaa gcgcccaagc tagaacttcc gtattgtcag
    17641 ttgaaaaggc atctccacgt ccgtcaagaa gagcttggta agagtcactg tattggtcgt
    17701 atttttggag tttgatttct ggatgattct tttcaaaata agtctcagca gtcgttcctt
    17761 ttgtgacaat taaggtttta ccttcaagtt gtttgacgtc tgtaatgaga ccagtcttag
    17821 gtgatacgac acccagagaa actttcatat atggaagggc aaaatcaact tgtttcttac
    17881 gttcgtcagt tactgtaaag ttagcaagag taatatctac cttgtttgaa atcaagtatt
    17941 ccgcacggtt ggcagcatcg actgaaatgt atttaacctt gacaccaagg tcttgagcta
    18001 gttggttccc tagttcaata tcgtagcctt ggtaagaacc atcattgtca acgtagccaa
    18061 acggtttttt atctccaaac acggcgattc gcagttcacc gctttttttt gatttcatcg
    18121 atagtgcgag ctttggcagt tgtttttcca gaggatgaac cagcgtttcc acctgagcta
    18181 caagcagtga taaagataag ggcaaaggca agtgctaaaa cagttaagag tggtttgaat
    18241 agtttcataa gaatctcctt tatagatatg agccaaattg gctaaagtca aagacgttta
    18301 aaaattcctg ggctcgtttg gtttgcggat tggtaaagaa ggcttgagct gttccttctt
    18361 cagcgatttt cccttggtcg aggaagataa tccggtcagc aatggcttgg gcaaactgca
    18421 tttcgtgggt tactaaaatc atggtacggc cttcttgggc caaatcattg ataagttcca
    18481 gcacctcacg caccatttct ggatccagcg aagcagtcac ctcgtcaaaa aggatgattt
    18541 ctggatgcat taggagggca cggacaattg caacacgttg cttctgtcca ccagataatt
    18601 gacgagcaaa gctatgttgt ttatccagca aaccgacacg atctagtaat tgcaaagctt
    18661 cttccgttac ttctttcttg tcccatcctt gagttttgat agggcctagg atgaggtttt
    18721 gtaagacatc cagatgggga aagagttcat aactttaaaa gaccatgcca atcttttggc
    18781 gaactaggtg aaaatctttt ttattttcaa cgatagactg accatccaga agaatatctc
    18841 caccttgaat actttctaag ccgttgaggc aacgaaggag ggtacttttc ccacaaccag
    18901 atggccctag gatgacaaca acttcccctt ttttgatttc tagagaaagt ccttggagga
    18961 tgggattgtc tccgaaggat ttttttagtt ccttgatttc taagatagtt tcagacattt
    19021 agtttctcca atgtttttct aagtgagtgg atagtttgga aatagggtag caaactgcga
    19081 aatataagat tagaatggtt ccataaatcc aaaatgaagc agttgggatg gtcaggcgat
    19141 tgctatcgat gatttgttgt ccaactttgg tcacttccac aaccccaatc aaaacaacta
    19201 atgaagtggt tttaatcatc cgagtgacaa gattgatagc ctgcggtagc agtcttctta
    19261 agacttgtgg gatgatgatg tggtagtaaa gttgaacatt agtcaagtcg agtgcctatc
    19321 cactttcaaa ctgatgttta gggagagaag tgatagctcc acgtaccaag tctcccattt
    19381 cagctgttcc ccagagggta aaaatgataa tagctgaagt ctcacctgag atattgatat
    19441 taaagtttcg agccaagcca aagtaaacga tgaagagtag caccagctgg ggcatgatac
    19501 ggataaattc cagatacaat cgtgttaaaa atcgtatgat tctagaatgg gaggtcatga
    19561 tgattcccat gactgttccg aacatcatgg ataagaggac agacaggatg gatatcccaa
    19621 tcgtaacgcc caacccctgt aagattctca ggagattatt tccttgaaag agtacttgga
    19681 ttcccgaatc ctgcatggcg ggtcctcctt tctatccagc taaagaccag tgagatgggt
    19741 agcagcatga tcagataagc aactaccaac atagctagcg caatgtctgt ctcatagtag
    19801 agaccaatca aatccttggc gacgtacatg aggtcggcca aagccactgc tgagaaaaca
    19861 gaggtttcct tgataaggaa aatgacattg gcactaaagg aggggagtgc caccgctgtt
    19921 gcttgcggaa gaaccacata gcgaaagacc tgtagaggtg tcagaccaat agcgaggcca
    19981 atctcctgct gggtttgact gatggcttcc agcccacttc ggaaagattc tgccatatag
    20041 gatcctccta aaaagacaag cccaagcgtt gcacagactt ctgaagatag gacaatcccg
    20101 attcggggaa gaccgaagta gagaaagaag agttgaatca aaaggggcgt attacgtgac
    20161 aattcaatgt aggctgtcgc tacttgcgcc aaaacaggga ttcgataatg tcggatgata
    20221 ctaacgatta aaccgagcag aaaggatccc aaaattcccc aaactgcaat atgcaaggtc
    20281 agaaagaatg ccttttgata tagtggtaga tattgttcaa caatggacca atccaaaaat
    20341 agaacctccc atctagaaat aatacagtta ttgtagcact taaaatcttc tttggataat
    20401 atctattttt tattgccgtt ataaggattt tttaccatag acataaaatt tctgaaattt
    20461 ccaaacaaaa tatttgaaaa gttttgaaaa agagttaaga tatttttgta atatacaaag
    20521 taaacgctta cttatcaagg agggcatttt atgtcataca aaacaagtaa tgcagaaggt
    20581 catgtagact tcatcaatac ctatgatttg gagccaatgg cgcaacaagt tattcctaaa
    20641 gcagcatttg gctatatcgc tagtggggcg gaagatactt tcacttcttt tcagtgattt
    20701 tagcgtcagg ttctttttag tttttaaaga ttatccgtga atttcttgct tatttatgat
    20761 aaaatggggg tatcgcaaaa aatgactcat cgtattcaat tttgagtaaa actaggagga
    20821 tcccatgtct acagaacata tggaagaact aaatgaccag cagatcgttc gccgtgaaaa
    20881 aatggctgcg ctccgcgaac aaggaatcga tcctttcgga aaacgttttg aacgtactgc
    20941 aaattcacaa gaattaaaag ataaatatgc caacctcgat aaagaacaat tacacgataa
    21001 aaacgaaaca gctactatcg caggacgctt ggtaaccaaa cgtggtaaag gaaaagttgg
    21061 ttttgcccac cttcaagacc gcgaaggcca gattcagatc tacgttcgta aggatgctgt
    21121 cggtgaagaa aactacgaaa tcttcaaaaa agcagacctt ggtgacttcc ttggtgtcga
    21181 aggtgaagtg atgcgtacgg atatgggaga actctctatc aaggcaaccc acatcacaca
    21241 cttgtctaag gctcttcgtc ctcttcctga gaaattccat ggtttgacag acgttgaaac
    21301 aatttaccgt aaacgttacc ttgacttgat ttctaaccgt gaaagctttg aacgctttgt
    21361 cactcgttca aaaatcatct ctgaaatccg tcgttacctt gaccaaaaag gattccttga
    21421 agtggaaaca cctgttcttc ataatgaagc cggtggtgct gctgcccgtc catttatcac
    21481 ccaccacaat gcccaaaaca ttgacatggt gcttcgtatc gcgactgagc ttcacttaaa
    21541 acgccttatc gtgggtggta tggaacgtgt ctatgaaatt ggccgtatct tccgtaacga
    21601 aggaatggac gctactcata accctgagtt cacttctatc gaagtttacc aagcttatgc
    21661 agacttccaa gacatcatgg acttgacgga aggcattatc caacacgctg ctaaatcagt
    21721 caaaggtgat ggcccagtca actaccaagg tactgaaatc aagattaacg aaccatttaa
    21781 gcgtgttcat atggtggatg ctatcagaga aattactggt gtcgatttct ggcaagacat
    21841 gactttggaa gaagctaaag ctatcgctgc tgagaagaaa gttccagttg agaaacacta
    21901 cactgaggtt ggtcacatca tcaatgcctt ctttgaagag tttgttgaag aaactttaat
    21961 ccaaccaacc tttgtctatg gacatccagt agctgtatct ccactcgcta agaaaaatcc
    22021 tgaagaccaa cgctttactg accgtttcga gctctttatc atgactaagg agtacggtaa
    22081 tgcctttact gagctcaacg acccaatcga ccaacttagc cgttttgaag cccaagctaa
    22141 agccaaagaa cttggtgatg atgaagcgac aggaatcgac tatgactaca tcgaggctct
    22201 tgaatacggt atgccaccaa caggtggttt gggaatcggt atcgaccgtc tctgcatgct
    22261 cctcactgat acaacaacta tccgtgatgt attactcttc ccaacaatga aataaattct
    22321 tatcctctgg ctcttaccag aggatttttt gattcaaaaa gagactgaat ttaaggagaa
    22381 aatgaagtgt agtatattga agttgaaata gtacactttg atttctaaga cattgttaga
    22441 aattggttta aattccctaa gcaatttgtg catgttttat ttcattttac gatagtacgc
    22501 tgaaactttt caaaaagtac tagaaattga cttggattcc ccaattgatt tgttcagatt
    22561 cactataaat aaaaaattaa taagtgggat aggaagttag cgtcaactag gatagtatct
    22621 tgcttaaaca gtatatatgg gactgatata agtccatagg tcctattaga ggatgttctg
    22681 gtgtcttatt cacttgtttt tttatagtat tagtagatag aatcagcaaa taaaaaagta
    22741 gttcaaatgc ctggcagcaa aaaatctcaa cgattcactt aatatagact aaggtttaga
    22801 gtttaaggaa agtagggcta gtatattgta tgaaaaaata agatggtttt taagcaaaac
    22861 tcttgaaaat gattgaaaaa agagttatta tagttgtata gtaaaaagca aacgcttact
    22921 taatcgagga ggacagttta tgtcatacaa aacaagcaat gcagaaggtc atgtagactt
    22981 catcaatacc tatgatttgg agccaatggc gcaacaagtt attcctaaag cagcatttgg
    23041 ctatatcgct agtggggcgg aagatacttt cactttaaga gagaatatcc gtgcctttaa
    23101 ccacaagctc atcgttcctc atacactttg caatgtagaa aatccaaata cagagattga
    23161 atttgcaggt gaaaaactat cttctccaat cattatggca cctgttgcgg ctcataaatt
    23221 ggcaaatgaa cagggggaag tggcgactgc gcgtggtgtg catgagtttg gttctcttta
    23281 tacaaccagt tcttactcta ctgttgacct tccagagatt tctgaagccc ttcaagggac
    23341 acctcattgg tttcaatttt actttagtaa ggatgacggt atcaaccgcc acatcatgga
    23401 ccgtgtgaag gctgaaggtt ataaagcgat tgtcttgacg gcagatgcta ctgtaggggg
    23461 gaatcgtgaa gtggataagc gtaatggttt tgtcttccca gttggcatgc cgattgttga
    23521 agaatacctg ccagaaggtg ctggtaaatc aatggacttt gtttacaaat cagctaaaca
    23581 acgcttgtct ccacgcgatg tagaatttat cgctgaatac tctggtcttc ctgtgtatgt
    23641 caagggacca caatgccgtg aggacgttga acgttcgctt gctgcaggag cttctggtat
    23701 ctgggtaacc aaccacggtg gtcgtcaaat cgacggtgga ccagctgcct ttgactcgct
    23761 tcaagaagtg gcagaagcag ttgatagacg tgtgccgatt gtctttgact ctggtgttcg
    23821 tcgtggtcaa cacgtcttta aagccttggc atcaggagca gacttggttg ctattggacg
    23881 ccctgtcatc tatggcttgg ctctcggtgg tagtgtcggt gtgcgtcaag tctttgaaca
    23941 cttgaatgcg gaattgaaga cagttatgca attgtctgga gctcagacca ttgaagatgt
    24001 caaacacttc aagctccgtc acaatccata caacccaacc ttcccagttg accctcgtga
    24061 cttaaaattg tattgataaa acagattgcc tccactgaat gtggaggttt ttcttcgtgt
    24121 attggaagaa taaattgcta tcgaaaacta tagtaaaatg aaataagaat aggacaaatc
    24181 aatcaggaca gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag
    24241 tttcaatcta ctatataaag atatttttcg gtcaaatatc ttgctagggc tttcattttt
    24301 tgctatactg gttcagtaat taaataatag agacatttgg ggtgctttaa gctgagatga
    24361 tacccattga acctgataca gttaagactg gcgaagggaa atgtgaaacg ttttttcgta
    24421 tggcgaaatg aacgatctaa tcttgtaagt caactctaat tcttgattgt aattggagtt
    24481 ttttgtttat ataaactgga taggcttgtt tagttagctc tctgcaaatg ctctcgatgt
    24541 gctttaaaag gatcaagtgg aattacgatt ttgcttgata tttcttggtg ttttattaat
    24601 tactaacaag taaagagagg agaagtaaat atggaaacac aagactatgc atttcagcca
    24661 ggtttgactg ttggagaatt attaaaaagc agtcagaagg attggcaggc tgcaatcaat
    24721 catcgttttg ttaaggaact ttttgcgggg acaattgaga ataaggtctt aaaggactat
    24781 ctgattcaag attatcactt ctttgatgcc ttcttatcca tgctgggtgc ctgcgtagct
    24841 cacgcagata aacttgaatc caagcttcgt tttgccaagc aactaggctt tcttgaagca
    24901 gatgaagatg gttatttcca aaaggctttt aaagagttaa aagtagcaga gaatgactat
    24961 ctagaagtga ctttgcaccc tgtaacaaaa gcctttcagg atctaatgta ttcggcggtg
    25021 gcttcatcag actatgccca tcttttggtc atgctggtca ttgcagaagg tctctattta
    25081 gactggggtt ctaaagattt ggctttacct gaagtctata ttcattcgga atggatcaat
    25141 ctccacagag gtcctttctt tgcagagtgg gttcaatttc tggttgacga actcaatcgt
    25201 gtcggtaaaa atcgagaaga tttgacagaa cttcagcaac gctggaatca agcagtcgct
    25261 ttagaattag ctttttttga tattggttac gatgtctaga gaaggctcat gatatttaca
    25321 aatttgatga ggtaagactc ttcgaaaatc tcttcaaacc acgtcagttc tatccacaac
    25381 ctcaaaacag tgttttgagc aacctgcggt tagcctccta gtttgctctt tgattttcat
    25441 tgagtataaa tcattcaatg taaatgaaaa aaattcttaa cgaaagatag aaataaatcg
    25501 aaatcagtag atcgtataaa gtgaaaagga aggatttcaa tatgacaagt ttaaaattat
    25561 taaaagaaaa agcaccattg gtcatttgta taaccaatga tgtagtaaaa aatttcacag
    25621 caaatggatt agtagcactg ggcgcctcac cagccatgag tgagtttcca gcagatttag
    25681 aggatttgtt aaagtatgct ggtggtttat taataaacat aggaacattg acagatgaaa
    25741 attggaaatt ataccaagct gctctgaaaa ttgcagagaa atataatgtc ccagcagttt
    25801 tagatcctgt agcctgtgga gcaggagaat atagaaaaaa agtagcagat gatctaatca
    25861 acaattataa actagcagcg attagaggaa atgctggcga gattgcctct ttagtaggaa
    25921 tagatgtggc atctaaagga gtagatagtg cgggcgtaga taatattgac gaaattgctc
    25981 tagcagcaaa tgagaagttc aatattccaa tagtagtaac aggtgaagtg gatgccattg
    26041 ctgttaatgg agaagtggta acgattcata atggtagtgc tatgatgccg aaagtcattg
    26101 ggacaggatg cttattaggg gcagtgatag caagctttat cggactagaa aaaggtcaag
    26161 aattgaaatc attagaaaca gcaatgttgg tttacaatat cgctggagaa atggcagaaa
    26221 aacgtccaaa tggacatctt cctgggacat ttaaagttga atttataaat gccttatacg
    26281 agattacaga tgaagatgta aaggaattca aaagagtgaa gtaagatgtt tcataaagaa
    26341 ttactaaaac tatattttat ttgtggaacg actacttgcc aaggaaaaaa tctatataca
    26401 gtcgttgagg aagccttaaa aggtggtata accttatttc aatttcgaga aaaaggtgag
    26461 ggtgctttag aaggcttaga aaaacttgaa ctagctatcc aaattaaaga actttgtaaa
    26521 aaatacaatg tgccgtttat cgttaatgat gatatcgatt tggcaatgga aattgacgct
    26581 gatggcgtac atgtaggtca agatgatatt ggtgttgatg aaattagaaa attgatgcca
    26641 gataaaataa ttggtctttc tataaaaaac gaggaagaat ttcaacaatc aaaagttgaa
    26701 tatgtagatt atgttggtgt tggtcctgta tttgataccc agtcaaagga tgatgctggt
    26761 ggtgctatag gttatgaagg tcttgaattg atgagaaaac tattgccaca aatgccttta
    26821 gttgcaattg gtgggataca gacgaaacat attaaagaca ttataaagac caatgttgac
    26881 ggcgtttcaa tcatttcggc aatatcgtat gcaaaaaata tagaaaaaac tgttcgggaa
    26941 atgagtgaac aatagatatc tatccttgga ttctaagtaa gtaggatttt ccttttttaa
    27001 aaagctatgt ctagattcag cttgaatagc taattcatca aacaggtcat ttgttttttg
    27061 caaaagaaag atctgctgtc tttgtgagtg caaggctgta tttccagttc aatttcttga
    27121 actagtataa aatgtgtgtt ataataatca cataattaaa taataaaggc atttggggtg
    27181 ctttaggctg agatgatacc cattgaacct gatacagtta agactggcga agggaaatgt
    27241 gaaatgtttt tttcgtatgt cgaaaagaac tgtctaatct tgtaagctga actctaattc
    27301 gtatctgtaa ttagagtttt ttcttttacg aaactggatg aagatgatat agtagattga
    27361 aataagatgc gaacaaatca attagaaaat tcaaattaat ttctagaaat attttagcat
    27421 tcttgtgtac tgttctaaat tcagtctgct atacaaagta tttaggtcgg tcttcttgag
    27481 tgccccactt ttctttaaaa aaggagtttt ttatgttgaa aaaatggcag ttaaaagatg
    27541 ttatcttgct tgctttcttg tctatctttt ttggtggggt tttcgttggt tcaggatatg
    27601 tgtataatat tctcagtcta ctcttaacac ctcttggttt gcaggccttt gccaatgaaa
    27661 tcctcttcgg tctctggtgt atggctgcgc ccattgctgc catctttgtt ccgagagtcg
    27721 gaagtgcaac gattggagaa gtgctagctg cgcttgctga agtcctttat ggtagccaat
    27781 ttggtctagg agctcttttg tctggcttgg ttcaaggttt gggaagtgaa tttggtttta
    27841 tcgtaactaa gaatcgctat gaaagttggc tctctctaac tgctaatagt attgggatta
    27901 cgcttgttag ctttgtctat gaatacatta agttaggtta ctacgccttt tcccttccgt
    27961 ttgtcctttc cttacttgtg gtacgtttta tttctgttta tttcttctgt accatcttgg
    28021 ttcgcgccat tgtcaaactc tatcatcagt ttgcaactgg aggaaaagca tagatgggtc
    28081 tggaactacg agcgattcag tccccaatct tctctgagcc gtttgatttt acttttcatg
    28141 cgcaagcctt taccttgtta gttgggagca gtggttcagg aaaatccagc ctttttcaag
    28201 tcattgctca agtcagttct cttccctata gtggtcaagt cctgatagat gggagcgagg
    28261 tcagtcaact ttctatcatc gcacgtgtcc agaaggttgg cattctcttt caaaatccca
    28321 atcatcaatt taccatggag agcttgtttg aggagctgat tttcaccttg gagaatatcg
    28381 gctatcacct tcaggaaatt gattctaaaa tagcagaggt tgtccagcaa tgtcgttgcg
    28441 aggcaatctt acaccgtccc attcatcacc tatcaggtgg ggaaaagcaa aaagcagcgc
    28501 tggctgtcct ctttgccatg aatcctaggg tctatctctt ggatgaacct tttgcttcca
    28561 ttgaccgcaa gagcagaatc gagatattgg agattctaaa agagttggct cttgatggga
    28621 agacagttat tttgtgcgac catgatttat ctgactataa agcctatatc gaccatatgg
    28681 ttgagctaag agacggaaaa ctaagggaaa taaatcaaat cccttcctat gagatgacac
    28741 aggttgcttc aaaggaagtt gcttctagcc cggaactatt ccatatgaac cgtgtgactg
    28801 gtgagcttgg taatcgcccc ctcttttcaa ttgctgattt cacattctat caagggattt
    28861 cctgtatcct gggtgacaat ggtgtcggga aatcaaccct ctttcggtct attcttcaat
    28921 ttcaaaagta taaggggcgc attgcatgga aggggacagt cctgaaaaag aaaaagagtt
    28981 tgtaccgtga tctgacgggt gttgttcagg aagctgagaa gcagtttatc cgagtcagtc
    29041 tgcgagagga gcttcaatta gatggacctg attctgaaag aaatcagcgg atttttcaag
    29101 ctttacgata ttttgatttg gagcaggcag tcgataagag tccctatcaa ttaagtggtg
    29161 gtcagcaaaa aattcttcag ctcctgacca tcttgaccag taaggcttcc gtgatcttgc
    29221 tagatgaacc ttttgcaggt ttggatgata gagcctgcca ttatttttgc aagtggattg
    29281 tggaggagag gaatcaagga agaagttttc tgctcattag tcatcgttta gaccctttga
    29341 tttctgtggt tgattattgg attgagatga ctagtcaggg tcttcggcat gtgaaagaag
    29401 tgaccattac caaaccactt acatctcaga gtagcaatac ccaaggggag gtgagatagt
    29461 atggtcaaag tagcaaccca gacaccgatt atcagtctct tcttgctgat tttatccttg
    29521 gaaacatctt tcattccttc gattgctctg aatctttcgg tagtcgcatt ttgtattctc
    29581 tttatgctct attaccgtcg atttaaaatg ttagcttgga tgatcatact tgccatttta
    29641 ccatcttttg ccaactactg ggcagttcag ttacacggag atgcttcaca ggcagtcatg
    29701 cttggaacga gggcctttgt gacagtttgt atcggccttg tctttgtttc ctctatttca
    29761 ctaaaagagc ttctcttgta cttggctcaa aaggggctat cacgctcttg gtcctatgcc
    29821 ttgattgtgg tattcaattc ctttcctctc attcagcaag aaatcaagtc cctcaaagaa
    29881 gcttgcctat tacgtggtca agaactgcat ttttggtcgc ccttgattta cagtaaggtt
    29941 ctgatgacag tctttaggtg gcgccatctt tacctgagag ctctgtctgc tcatggatat
    30001 gacgaacatg cacagttgaa gaatagctat cggacttttt atattcctaa aaaaacaaaa
    30061 ttaatctacc tgcttttctt tttattgctt caaaccagtc tatttttata aaggagttat
    30121 tatggaattt acagatattg cgatggaatt atccaagaaa gcttggcagg cttcctttca
    30181 tcatcccttt attttacaat tacaagaggg gaatttagaa cctgccattt tccgctatta
    30241 cctgattcag gatgcctact atctgaaggc tttctcagaa atctatcatc ttttggctga
    30301 taagacttca aaccaagaga tgaaaagact cttgaaacaa aatgctcagg gtttagtgga
    30361 gggtgagtta tttattcgcc aacaattttt caaggaattg gaaatcaacg accaggaaat
    30421 ggagcaacat ccaatcgctc caacctgtta tcattacatt tctcatattt ataggcaatt
    30481 tgcagaaccg aacttagcca tagcttttgc aagcttgctt ccttgtcctt ggttatacca
    30541 tgatataggc aaatcactta atcttaaacc atcaccaaat cctctctatc aacaatggat
    30601 tgaaacttat attacggatg agttagagca acagatcaga gaggagggag cactggtcaa
    30661 tcagctctat cgagaaagtg atgagacaga taagcaaaaa atgctagatg ccttccacat
    30721 cagtgttcat atggaagcca agttttggga aatggcctac caacaccaga catggaagag
    30781 cgatttacag tctttagaaa aaggagaaga atagaagcat gagaaagcac caattacaag
    30841 ttcacaaatt aaccatttta tctatgatga ttgcccttga tgtagtcctg acacctatct
    30901 ttcggattga gggaatggca ccgatgtcca gtgtagtcaa tattctagcg ggaatcatga
    30961 tgggacctgt ttatgccttg gccatggcta cagtgacagc ctttatccgt atgacgactc
    31021 aagggattcc gcctttagct ctcacaggag cgacttttgg agcccttcta gcaggtctct
    31081 tttataagta cggtcgaaaa ttttactttt ctgccttggg agaaattgtg ggaacaggta
    31141 ttattggctc tattgtttcc tatcctgtta tggtactctt tacaggatca gctgctaagc
    31201 ttagctggtt tatctacacg cctcgatttt tcggagcaac cttgattggt acagcgattt
    31261 cctttattgc ctttcgattt ttaatcaagc aggaattctt taaaaaagtg cagggatatt
    31321 tctttagtga aaggatagac tgatgcagga atttacaaat ccctttccta taggctctag
    31381 ttccctaatt cactgtatga ccaatgagat ttcttgtgag atgctggcaa atgggatttt
    31441 ggctctggga tgcaaacctg tcatggcaga tgatccccgt gaagttcttg attttactaa
    31501 gcaaagtcag gctctcttca tcaatttggg gcatttgtca gctgagaagg aaaaagcaat
    31561 ccgcatggca gcttcgtatg caaaccaatc ttctctcccg atggtagtag atgcggttgg
    31621 cgtaacgact tcatccattc gtaagagctt agttaaagac cttttagact atagacctac
    31681 ggtccttaaa ggaaacatgt cagaaattcg aagtcttgtt ggcttaaagc accacggcgt
    31741 tggggtcgat gcgagtgcta aagatcaaga aacggaggat ttgcttcaag tcttgaaaga
    31801 ctggtgtcag acctatcctg gtatgtcttt cttagttact ggccccaagg accttattgt
    31861 ttcggagaat caagttgctg tactggagaa tggctgtact gaattagact ggataacagg
    31921 gacaggagac ttggttggag ccttaacagc cgtttttctc agccaaggaa agactggttt
    31981 tgaagcttct tgcttagcag tctcttatct caatatcgct gctgagaaaa tagttgttca
    32041 aggaatggga ttggaagaat ttcgttacca agtactcaat cagctttcgc tcctaagaag
    32101 agatgaaaat tggctagata ccatcaaagg agaggtttat gaatagagaa gcacttagac
    32161 tatatctggt aaccaatcgc tatcaagatt ccgtggaaag ctttcttgca aaagttgaga
    32221 cggcctgccg ttcaggggtt accatagtcc aattgcgaga aaaaaatctc acaaccaatc
    32281 aatattatca actggcaaaa caagtcaagg aaataacaga tgcctatcag gtccccttga
    32341 taatcgatga tcggttggat gtttgtcttg cggttgatgc tgctggtctg catattggag
    32401 atgacgaact cccagtttcg gttgcccgac aagtcttggg tcctgaaaaa atcctcggtg
    32461 tcaccgctaa aacggttaaa agagctctgg aagcggagaa atcaggtgca gattacttgg
    32521 ggacaggagc catttttccg acaaccacca aggaaaatgc acccatcacc ctgatttcaa
    32581 ccttgaaaac aatttgccaa acggttgcca ttccaatagt tgctattggt ggcttgactt
    32641 cggagaatat tgatcagctt atgggcactg gcatagctgg tgtagctgtt gtacgtgatt
    32701 tgatgcaagc agaagatatt gaggcaaaaa cgcaagcctt tttaacaaag ttgcatgaca
    32761 ttctttccta attaatactc aatgaaaatc aaagagtaaa ctagaaagct agtcgcaggt
    32821 tgctcaaagt actgccttga ggttttagat aagactgacg aagtcagctc aaaacagtgt
    32881 tttgaagttg cagatggaag ctgacgtagt ttgaagagat tttcgaagag tataaaaact
    32941 ctctaattcc cttaaagtgg gaactagaga gtttttttct taatctttaa aagttgtatg
    33001 gttgactgga ccagaaccat gaccgagttg aggggcatct tgaatagctt ttgtgataaa
    33061 ggccttggcc ttatcaactg cctggtaaag actcttgccc ttggctagtt cagcagtaat
    33121 cactgcagca aaggtacatc cagtaccatg ggtgtgacag gtttgaattc gtgggctttc
    33181 ccagacaaat tgttcattct tggtaaagag gaaatcttta gcaccacctt tgagatgtcc
    33241 gcctttgata accacagact gaggaccaaa ttcttttaaa atcaggcgac cagcacgctg
    33301 catgtcttcg gggtcatgga ttgaaaaacc aacaatctct tctgcttcag gaagatttgg
    33361 cgtaataata gttgctagag gtagtaagtt tgttttgaga tagtctctag cacttgagtc
    33421 aatcaaggca tctccacttg tagcaaccat aacaggatca aggacatagg gacaatccag
    33481 ttttttaaga tagggttgga tgatttccat gatttcagta gtagccaaca ttccagtttt
    33541 tacagcctga ggtggaatat cagaaaagac actctccaat tgggctttca acatttgagg
    33601 agaaacgtgc tcgattagct gaacacctct ggtattttga gcgacaagac tggttacaac
    33661 agccattcca tagacatctc tcgcttggaa tgactttaaa tctgccataa tgccagcacc
    33721 accactaggg tcagtccctg caatggtcaa agcaacgggt aaataagtca tctaaaacct
    33781 cccaaccaac tgaagtttgt attcttaaga acaagctagt ctgttttaga aaggcaatag
    33841 aagactgcta gtccccatta tcatttccac ttccatcagc tagcattacc tagattgagt
    33901 cagagggatc taacagtcgt taatctcagc tttacgcacc cctagtggtt gttttctttt
    33961 ttctttagta tagcatattt ttattgttta tatagtaata tttgactgca aatcgttttt
    34021 caaatgatta aaattctatt tttcgaagaa aatattattt ctataattga caaatgtaga
    34081 ttttaagagt atactgatga gtgtaattga caaatgtaga ttttggaggt atggtaatgc
    34141 agatttcaga tgcagaatgg caggtcatga agattatttg gatgcagggg gagcagacca
    34201 gtacggattt gattagggtt ttggcagagc gatttgattg gtccaagtcc acggttcaga
    34261 cacttttggc tcggctggtt gagaaagagt gtttgactcg gaaaaaagaa ggcaagtcct
    34321 ttgtttattc agccctttta actctagacc aaagtcggga tttacttgtc caagatatca
    34381 aagacaaggt ttgttcccgt aggattagga atttgttggc tgacttgatt gtagaatgtg
    34441 aatttactca gactgacttg gaagacttgg aagctgtgat ttcagagaag aaatcaagtg
    34501 ctgtaacaga agtaagatgt aattgtatgt aaaggagacg tcatgttaaa tagtattgta
    34561 accattattt gtattgccct tatcgcgttt atcttgtttt ggtttttcaa aaagcctgaa
    34621 aaatctggac aaaaagccca gcaaaaaaac ggataccaag agattcgagt ggaagtcatg
    34681 ggaggctata ctcctgagtt gattgtcctc aagaaatcag tgccagcacg cattgtcttt
    34741 gaccgcaagg atccttcacc atgtctggat caaattgttt ttccagattt tggtgtacat
    34801 acgaacctgc caatggggga agagtatgta gtggaaatca cgcctgagca ggctggagag
    34861 tttggctttg cttgtggtat gaacatgatg cacggcaaga tgattgtaga gtaggtggag
    34921 actatgacag aaattgtgaa agcaagctta gaaaatggca ttcaaaaaat ccgtatccga
    34981 gctgaaaaag gctatcatcc agcccatatc cagcttcaaa agggaattcc agctgagatt
    35041 acctttcatc gtgctactcc ttcaaactgt tataaggaaa ttctgtttga agaagaaggt
    35101 atcttggaac caatcggcgt agatgaggag aaagtcattc gttttacacc tcaagaatta
    35161 gggcgacatg aattttcttg tggcatgaag atgcaaaagg gaagctatat agtcgttgag
    35221 aagactcgaa aatctctatc tctcctgcaa cgtttttgga ttactagtat ctttactgtg
    35281 cctcttgtga ttctcatgat tgggatgttg gcaggtagca ttagtcatca agtcatgcat
    35341 tggggaacct ttttagcaac aacgcctatt atgttagttg caggtaagcc atatatccag
    35401 agtgcttggg ccagttttaa aaagcacaat gccaacatgg ataccttggt tgcgctggga
    35461 actctagtgg cttatttcta tagcctagtt gctctctttg ctggtctccc tgtttacttc
    35521 gaaagtgctg gatttatcct ctttttcgtt cttttgggag cagtttttga ggaaaaaatg
    35581 agaaaaaata cgtcccaagc tgtggagaaa ttactggact tgcaagctaa aaccgcagaa
    35641 gtcttgagtg atgatagtta tgtccaagtt cctttggaac aagtcaaggt aggcgacctg
    35701 attcgagtgc gtcccggtga aaagattgct gttgatggtg tcgtagtaga aggtgtctct
    35761 agtattgacg aatccatggt gacaggtgag agtctgcctg tggacaagac agttggagat
    35821 actgtcattg gctcaaccat caatcatagt ggaacgcttg tctttagagc agaaaaagtt
    35881 ggctcagaga ctgttttggc tcagattgtg gattttgtga agaaagctca gacaagtcgt
    35941 gcgccgattc aggacttgac ggataagatt tcagggattt ttgtcccagt agttgtcatt
    36001 ttaggaatca tgaccttttg ggtttggttc gtcttgctca gggatagtgt ggtcgtgctt
    36061 ggagctagct ttgtgtcctc tcttctctac ggagtggcgg ttttgattat cgcctgtcct
    36121 tgtgccttgg gacttgcaac accgacagcc cttatggtgg ggacaggacg tagtgccaag
    36181 atgggggttc tcctcaaaaa tggaactgtc ttacaggaaa tccagaaagt tcaaactctt
    36241 gtctttgata agaccgggac tttgacggaa gggaaacctg tggtaacaga tatcatcggc
    36301 gacgaagtag aagtgtttgg attggcagcc tccttggaag atgcttctca acacccactg
    36361 gctgaggcta tcgttaagcg agcgagtgaa gctggacttg agtttcaaac tgttgaaaat
    36421 tttcaggcct tgcacgggaa aggtgtttca gggcgagtca atggaaaaca agttttactt
    36481 ggaaatgcta aaatgctgga tggcatggat atttctaata cttatcaaga taaactagaa
    36541 gaactagaaa aagaagctaa gacagttgtg tttttagctg ttgacaatga aatcaaaggc
    36601 ttgcttgctt tgcaagatat tcctaaggaa aatgctaagc tagccatcag tcagctaaaa
    36661 aaacgtggtc tccgaacagt catgctgaca ggagacaatg ctggtgtggc gcgtgctatt
    36721 gcagatcaaa tcggaattga agaggtcatt gcaggcgtct tgccagaaga aaaagcccat
    36781 gaaatccata aactgcaagc ggctggcaaa gtagcctttg ttggggacgg tatcaatgac
    36841 gctcctgccc ttagtgtagc agatgtggga attgctatgg gtgctggaac agatatcgcc
    36901 atcgagtcag cagatttggt gttgacaacc aataatcttt taggagtggt tcgtgccttt
    36961 gatatgagta agaaaacctt tcatcgaatt ctactcaatc ttttctgggc ttttatctac
    37021 aatgttgtcg gaattccgat tgcagcagga gtcttttcag gtgttggact ggctctcaac
    37081 ccagaattgg caggtctagc catggccttt agttctgtat ctgttctgac cagttccctt
    37141 ctgttaaatt ttagtaaaat agactaaaag taatgactag atttctttgt tataaaacag
    37201 aaatgacaac actttcaaaa ctgtattaga atagagaata gagagttttg agcagatttt
    37261 tagaaaagtc agcataaata tgatacagtg gaatagtaaa aatttggaga acgtttccaa
    37321 ttctatgtaa tcgtattctc caagtttaaa aaaattgaag gagagttatc attatgactc
    37381 aagggaaaat tactgcatct gcagcaatgc ttaacgtatt gaaaacatgg ggcgtagata
    37441 caatctacgg tatcccatca ggaacactca gctcattgat ggatgctttg gctgaagaca
    37501 aagatatccg tttcttacaa gttcgccacg aagagacagg tgctcttgca gcggttatgc
    37561 aagctaaatt cggcggctca atcggggttg cagttggttc aggtggtcca ggtgcgactc
    37621 acttgattaa cggtgtttac gatgcagcta tggataacac tccattccta gcgatccttg
    37681 gatcacgtcc agttaacgaa ttgaacatgg atgctttcca agagcttaac caaaacccaa
    37741 tgtacaacgg tatcgctgtt tacaacaaac gtgtagctta cgctgagcaa ttgccaaaag
    37801 taattgacga agcctgccgt gctgcagttt ctaaaaaagg tccagctgtt gttgaaattc
    37861 cagtaaactt cggtttccaa gaaatcgatg aaaactcata ctacggttca ggttcatacg
    37921 aacgctcatt catcgctcct gctttgaacg aagttgaaat cgacaaagct gttgaaatct
    37981 tgaacaatgc tgaacgccca gttatctatg ctggatttgg tggtgttaaa gctggtgaag
    38041 tgattactga attgtcacgt aaaatcaaag caccaatcat cacaactggt aaaaactttg
    38101 aagctttcga atggaactat gaaggtttga caggttctgc ttaccgtgtt ggttggaaac
    38161 cagccaacga agtggtcttt gaagcagaca cagttctttt ccttggttca aacttcccat
    38221 tcgctgaagt ttacgaagca ttcaagaaca ctgaaaaatt catccaagtc gatatcgacc
    38281 cttacaaact tggtaaacgt catgcccttg acgcttcaat ccttggtgat gctggtcaag
    38341 cagctaaagc tatccttgac aaagtaaacc cagttgaatc aactccatgg tggcgtgcaa
    38401 acgttaagaa caaccaaaac tggcgtgatt acatgaacaa actcgaaggt aaaactgagg
    38461 gtgaattgca attgtatcaa gtttacaatg caatcaacaa acatgctgat caagacgcta
    38521 tctactcaat cgacgtaggt aacactactc aaacatctac tcgtcacctt cacatgacac
    38581 ctaagaacat gtggcgtaca tctccactct ttgcgacaat gggtattgcc cttcctggtg
    38641 gtatcgctgc taagaaagac aatccagatc gccaagtatg gaacatcatg ggtgacggag
    38701 cattcaacat gtgctaccca gacgttatca caaacgttca atacgacctt ccagttatca
    38761 accttgtctt ctcaaatgct gagtacggct tcatcaagaa caaatacgaa gatacaaaca
    38821 aacacttgtt tggtgtagac ttcacaaacg ctgactacgc taaaattgcg gaagctcaag
    38881 gagctgttgg attcacagtt gaccgtatcg aagacatcga tgcagttgtt gcagaagctg
    38941 ttaaattgaa caaagaaggt aaaactgttg tcatcgatgc tcgcatcact caacaccgtc
    39001 cacttccagt agaagtactt gaattggatc caaaacttca ctcagaagaa gctatcaaag
    39061 ccttcaagga aaaatacgaa gcagaagaac tcgtaccatt ccgtctcttc ttggaagaag
    39121 aaggattgca atcacgcgca attaaataat tcctctcgcc gaaaatcaaa tatgaaactt
    39181 gtagacttta ttctttgatt ttcatagagc agaactttaa aagatcggag caatccggtc
    39241 tttttatgga ggagagtaaa tgaatttaaa tcaattagat attatcgttt caaatgttcc
    39301 ccaagtctgt gctgacttgg agcatatctt ggataaaaag gcagattatg ctgatgatgg
    39361 ttttgctcag tttacgattg gtagtcactg ccttatgttg tcacaaaatc atttggttcc
    39421 tttggaaaac tttcagtcag gaatcattat tcatatcgag gttgaggatg tagaccagaa
    39481 ctacaaacgg ttgaacgagc ttggtataaa ggttttacac ggaccaactg taaccgattg
    39541 gggaacagag tccttattag ttcaaggacc tgctggtcta gtgcttgatt tttatcgtat
    39601 gaaataggtc gcgtagtcat ttgacgttaa ccttagctat ttttaaaata gaaattgaga
    39661 atatgaacta ttgaaagatc ggagcaatcc ggtcttttta tataaagaaa ttgcatataa
    39721 tactcatctg ctttcaaaaa gcattctagt ccatctctga ttaacgatgg actttatcac
    39781 ctccttctcc agtccttgta tgacatcttg aagttgattc atgacatctt ccaaagttcg
    39841 aaaggcttta ttcttaaatc cacgtttacg aatctctttc cacacttgtt caatggggtt
    39901 catctctggt gtgtatggag gaataaatgc aaaaccaata ttagtcagaa tctttaaggt
    39961 acttgattta tgccatatag cattgtccat aacgagtaaa aaataatcat ctggataagc
    40021 ttgtgaaagc tcttctaaaa agacgttcat ccactcagta ttacatccac cagctcttaa
    40081 gaaaaatgat tcgcctgtat aggcatcaac agctccataa taatagcgaa attctcgtat
    40141 atagtgacta tggacatgtg gacctactcc tattggagac caacaagatc ccagtttact
    40201 gattctaccg aaaccagcct catcttggta catcaagcga accttatgaa aacgtctact
    40261 atatttaaaa cgctttcttg tcttcttgaa t
//
LOCUS       DBEJZV010000021        37904 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.21, whole genome shotgun sequence.
ACCESSION   DBEJZV010000021 DBEJZV010000000
VERSION     DBEJZV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 37904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37904
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.21"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            364..840
                     /locus_tag="ACL3S0_001315"
     CDS             364..840
                     /locus_tag="ACL3S0_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR1312218.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            878..1183
                     /locus_tag="ACL3S0_001316"
     CDS             878..1183
                     /locus_tag="ACL3S0_001316"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1312219.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            1231..2706
                     /locus_tag="ACL3S0_001317"
     CDS             1231..2706
                     /locus_tag="ACL3S0_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGR1312220.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            2732..2923
                     /locus_tag="ACL3S0_001318"
     CDS             2732..2923
                     /locus_tag="ACL3S0_001318"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312221.1"
                     /translation="MKIKEQTRKLATGCSKHSFEVVDKTDEISSKHGFEVVDETDEVS
                     NHIYGKATLTKFELDFRRV"
     gene            3011..9712
                     /gene="bgaA"
                     /locus_tag="ACL3S0_001319"
     CDS             3011..9712
                     /gene="bgaA"
                     /locus_tag="ACL3S0_001319"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGR1312222.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     ELDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKTLRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGQTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9960..10406)
                     /locus_tag="ACL3S0_001320"
     CDS             complement(9960..10406)
                     /locus_tag="ACL3S0_001320"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR1312223.1"
                     /translation="MFDKEQKRGYKQSAKNLANWHYNDKEDSYIHPDGWCYRFHHIKY
                     QKTQTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQDRQIFAQRKI
                     DVEPVFGQIKACLGYKRCNLRGKRQVRIDMGLVLMANNLLKHSEMK"
     gene            complement(10571..10816)
                     /locus_tag="ACL3S0_001321"
     CDS             complement(10571..10816)
                     /locus_tag="ACL3S0_001321"
                     /inference="COORDINATES: protein motif:HMM:NF017416.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR1312224.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEERHFYTS
                     YHAFGRPSYHPKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            complement(11027..11386)
                     /locus_tag="ACL3S0_001322"
     CDS             complement(11027..11386)
                     /locus_tag="ACL3S0_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGR1312225.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            11478..12434
                     /locus_tag="ACL3S0_001323"
                     /pseudo
     CDS             11478..12434
                     /locus_tag="ACL3S0_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            12418..12975
                     /locus_tag="ACL3S0_001324"
     CDS             12418..12975
                     /locus_tag="ACL3S0_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR1312226.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12968..13222
                     /locus_tag="ACL3S0_001325"
     CDS             12968..13222
                     /locus_tag="ACL3S0_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312227.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            13234..15288
                     /locus_tag="ACL3S0_001326"
     CDS             13234..15288
                     /locus_tag="ACL3S0_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGR1312228.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            15467..16327
                     /locus_tag="ACL3S0_001327"
     CDS             15467..16327
                     /locus_tag="ACL3S0_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGR1312229.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLRDPVFKKD"
     gene            16538..17248
                     /gene="ccdA2"
                     /locus_tag="ACL3S0_001328"
     CDS             16538..17248
                     /gene="ccdA2"
                     /locus_tag="ACL3S0_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR1312230.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            17268..17834
                     /locus_tag="ACL3S0_001329"
     CDS             17268..17834
                     /locus_tag="ACL3S0_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGR1312231.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            17845..18957
                     /gene="msrB"
                     /locus_tag="ACL3S0_001330"
     CDS             17845..18957
                     /gene="msrB"
                     /locus_tag="ACL3S0_001330"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR1312232.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            19270..20007
                     /locus_tag="ACL3S0_001331"
     CDS             19270..20007
                     /locus_tag="ACL3S0_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR1312233.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            20004..21695
                     /locus_tag="ACL3S0_001332"
     CDS             20004..21695
                     /locus_tag="ACL3S0_001332"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR1312234.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDARGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPPKGTKVEIYINRIETS"
     gene            21811..22374
                     /locus_tag="ACL3S0_001333"
     CDS             21811..22374
                     /locus_tag="ACL3S0_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGR1312235.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            22396..27885
                     /gene="zmpB"
                     /locus_tag="ACL3S0_001334"
     CDS             22396..27885
                     /gene="zmpB"
                     /locus_tag="ACL3S0_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease B"
                     /protein_id="HGR1312236.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKSELQEQLRVAEQKQQADYSAKTWREFKIAELQAKEINNPTTPLPKQSEIDAAT
                     KALQDALQALAVDKTVLQNAINTANSKREEEYTAQTWKALKDALTAVNPVNEDETATQ
                     SKVDEATRNLEEAINNLVLLTEKPVLTFIETDKKALEREVVAKYSLENQNKTKIKSIT
                     ATLKKGETVVSTVELIGDDVTNETITSAFKNLEYYKEYTLSTTMVYDRGDGDVTEILD
                     NQPIQLDLKKVELKNIKRTDLIKYENGKETNESLITTVPDDKRNYYLKITSKNQKTTL
                     LAVKNIEETTVNGTPVYKVTAIADNLVSRTADNKFEEEYVHYIEKPKVHEDNVYYNFK
                     ELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYITKEFTGKLLSSEGKQFAITELEHPL
                     FNVITNATINNVNFENVEIERSGQDNIASLANTMKGSSVITNVKITGTLSGRNNVAGF
                     VNNMNDGTRIENVAFFGKLHSTSGNGSHTGGIAGTNYRGIVRKAYVDATITGNKTRAS
                     LLVPKVDYGLTLDHLIGTKALLTESVVKGKIDVSNPVEVGAIASKTWPVGTVSNSVSY
                     AKIIRGEELFGSNDVDDSDYASAHIKDLYAVEGYSSGNRSFRKSKTFTKLTKEQADAK
                     VTTFNITADKLESDLSPLAKLNEEKAYSSIQDYNAEYNQAYKNLEKLIPFYNKDYIVY
                     QGNKLNKEHHLNTKEVLSVTAMNNNEFITNLDEANKIIVHYADGTKDYFNLSSSSEGL
                     SNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSILESVELQSQTMYQHLNRLGDYRVN
                     AIKDLYLEESFTDVKENLTNLITKLVQNEEHQLNDSPAARQMIRDKVEKNKAALLLGL
                     TYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVLDRLIEIGSKENNIKGSRTFDAFGQ
                     VLAKYTKSGNLDAFLNYNRQLFTNIDNMNDWFIYATEDHVYIAERASEVEEIKNSKHR
                     AFDNLKRSHLRNTILPLLNIDKAHLYLISNYNAIAFGSAERLGKKSLEDIKDIVNKAA
                     DGYRNYYDFWYRLASDNVKQRLLRDAVIPIWEGYNAPGGWVEKYGRYNTDKVYTPLRE
                     FFGPMDKYYNYNGTGAYAAIYPNSDDIRTDVKYVHLEMVGEYGISVYTHETTHVNDRA
                     IYLGGFGHREGTDAEAYAQGMLQTPVTGSGFDEFGSLGINMVFKRKNDGNQWYITDPK
                     TLKTREDINRYMKGYNDTLTLLDEIEAESVISQQNKDLNSAWFKKIDREYRDNNKLNQ
                     WDKIRNLSQEEKNELNIQSVNDLVDQQLMTNRNPGNGIYKPEAISYNDQSPYVGVRMM
                     TGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYENGFLGYASNKYKQQSKTDGESVLSDE
                     YIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLTTFEVNGSSVSSYDDLLTLFKEAVK
                     KDAETLKQEANGNKTVSMNNTVKLKEAVYKKLLQQTDSFKTSIFK"
     gene            27946..29667
                     /gene="pabB"
                     /locus_tag="ACL3S0_001335"
     CDS             27946..29667
                     /gene="pabB"
                     /locus_tag="ACL3S0_001335"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGR1312237.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADFLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELILEEN"
     gene            29668..30285
                     /locus_tag="ACL3S0_001336"
     CDS             29668..30285
                     /locus_tag="ACL3S0_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR1312238.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            30335..31093
                     /locus_tag="ACL3S0_001337"
     CDS             30335..31093
                     /locus_tag="ACL3S0_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGR1312239.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLTSDGSYAYSTWQGN
                     YYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTASSSNDSNSEYSAALGKAKSYNS
                     LFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            31220..32179
                     /locus_tag="ACL3S0_001338"
     CDS             31220..32179
                     /locus_tag="ACL3S0_001338"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGR1312240.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGNNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            32276..33115
                     /locus_tag="ACL3S0_001339"
     CDS             32276..33115
                     /locus_tag="ACL3S0_001339"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGR1312241.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(33163..33333)
                     /locus_tag="ACL3S0_001340"
     CDS             complement(33163..33333)
                     /locus_tag="ACL3S0_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGR1312242.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            33454..34338
                     /gene="miaA"
                     /locus_tag="ACL3S0_001341"
     CDS             33454..34338
                     /gene="miaA"
                     /locus_tag="ACL3S0_001341"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGR1312243.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            34331..35569
                     /gene="hflX"
                     /locus_tag="ACL3S0_001342"
     CDS             34331..35569
                     /gene="hflX"
                     /locus_tag="ACL3S0_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGR1312244.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     NYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            35562..36185
                     /locus_tag="ACL3S0_001343"
     CDS             35562..36185
                     /locus_tag="ACL3S0_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGR1312245.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     DSDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            36200..37129
                     /gene="rnz"
                     /locus_tag="ACL3S0_001344"
     CDS             36200..37129
                     /gene="rnz"
                     /locus_tag="ACL3S0_001344"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGR1312246.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKISKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            37150..>37904
                     /locus_tag="ACL3S0_001345"
     CDS             37150..>37904
                     /locus_tag="ACL3S0_001345"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR1312247.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLVGETFNYK"
BASE COUNT        11792 a         7048 c         8245 g        10819 t
ORIGIN      
        1 ttaagtagcg tttggttgct taattccttt ttatttggaa ggaagttttt cgtaaccgcc
       61 caataacgaa gtctattggg cggttacgat atgatcactg acttcgtcag ttctatctac
      121 aacctaaaaa cagtgttttg aacaacctgc ggctagcttc ctagtttgct ctttgatttt
      181 cattgaatat tagaacagca aaaatgcttg gagtatttgt ttgtgtgttt gtttttatat
      241 aacaaactat aaacaaaaca aaaatataaa aaaagagaca aaaaagaaca aaaagtaatt
      301 gacaacggtt tcatatagtg ttatacttat ggcataaagt taatggaaag aagggaaaac
      361 cttatggtat tagattattt ctttgacaaa aaccttgtgt tttgcttaga agcggataat
      421 caagaacaac tctttgatca ggttgcaact ttattggaag aacgagaaat tgtcactcca
      481 acttatcgtg aagccttgat cacgcgtgaa aagtcatttc caactggttt agatatggaa
      541 tttctaggaa aggacttgcc aaatgtagcg attcctcata cagatattgt tcataatcta
      601 gctgagaaag tggtggttgt tcgattagaa aaaccagtaa cttttcacaa tatgatagct
      661 cctgataagg aagtagaagt atccttgctc ttctttatca tcaataactc aagttcaagt
      721 caaacaaata ttctggctca gttgatggac tttttcacag gaaatggaca tcttgaagac
      781 ctatcaaaaa tttccgaacc agaaaaactt tatgcttaca ttgctgaagc aaccgcttaa
      841 tcttgtctat taaaaaataa aatcggagga aatctaaatg attaaaattc ttgctgcctg
      901 cggtgcaggt gttaactcaa gtcaccaaat taaaagtgct ctagaagaag aactttcaaa
      961 ccgtggttat gatgttcact gtgatgcagt catggtgaaa gatgtaaacg aagaccttat
     1021 gaaaggttac gatatcttta caccaatcgc tgcaacagac cttggttttg aaccaggtat
     1081 cccagttatc gaagctggac caatcttatt ccgtatccca gcaatgagcg ctccagtatt
     1141 tgacaatatt gaagcagcta ttaaagaaca cggattaagc taattctaat ttgttaacat
     1201 tcatataaca taaaaaaggg aggaactgtt atggatgcaa tctttgacct aatcggaaag
     1261 gttttcaatc ccatcttaga aatgggtgga cctgtcatca tgttaatcat tttgacagta
     1321 ttggctttac tttttggagt gaaattctcc aaagcacttg aaggtggtat caaacttgcc
     1381 atcgctctta caggtatcgg tgctatcatc ggtatgctaa atggtgcttt ctcagcatca
     1441 cttgcaaaat tcgttgaaaa cactggtatc caattgagta ttaccgacgt tggttgggca
     1501 ccactcgcaa caatcacttg gggttctgct tggacactat acttcttgct catcatgttg
     1561 attgtcaacg tagtgatgct tgctatgaag aaaaccgata cacttgatgt cgatatcttt
     1621 gatatctggc acttgtctat cacaggtctc ttgattaaat ggtatgctga taacaatggt
     1681 gtgagtcaag gggtttcact ctttattgct acagcagcta tcgtccttgt cggtgtgttg
     1741 aaaattatca actctgactt gatgaaacct acatttgatg accttcttaa cgccccaagt
     1801 tcatcaccaa tgacatcaac tcacatgaac tacatgatga acccagttat catggttttg
     1861 gataagattt ttgaaaaatt cttcccaggc cttgataaat atgactttga tgctgctaaa
     1921 ttgaacaaga aaatcggttt ctggggatct aaattcttca tcggtttcat ccttggtatc
     1981 gttatcggta ttatgggaac tccacatcca attgcaggtg ttgcagatgc agataaatgg
     2041 cgtcttgtta tcaaaggatg gttgtctctt ggtttgactg ccggtgtatc tttggaactc
     2101 ttctcactta tcggttcatg gttcatcgca gccgtagaac cactatcaca aggtattaca
     2161 aacgttgcta ctaaacgtct tcaaggacgt aaattcaata tcggtcttga ctggccattc
     2221 atcgctggtc gtgctgaaat ctgggcttgt gccaacgtac ttgcaccaat catgttgatt
     2281 gaagcagtgc ttctttcaaa agttggaaat ggtatcttgc cacttgcagg tatcatcgct
     2341 atgggtgtta ctccagctct cttggttgta actcgtggta aattgctccg tatgattatc
     2401 ttcggaacac tcttgttgcc actcttcctt ctttcaggta cccttattgc accatttgca
     2461 acagaacttg ctaaaggtgt aggtgccttc ccagaaggtg tgagccaaac tcaattgatt
     2521 actcactcta ctcttgaagg accaatcgaa aaacttcttg gttggacaat tggtaacact
     2581 acaactggtg atatcaaagc aatccttggt gcagtagcct tccttgtatt ctatatcggt
     2641 atctttgctt ggtacagaaa acaaatgatc aaacgtaacg aagagtacgc agcaaaagca
     2701 aaataatgcg ctcctataaa atataaactc aatgaaaatc aaagagcaaa ctaggaaact
     2761 agccacaggt tgctcaaaac acagttttga ggttgtagat aagactgacg aaatcagctc
     2821 aaaacatggt tttgaggttg tagatgaaac tgacgaagtc agtaatcata tctacggcaa
     2881 ggcgacgctg acgaagtttg aattggattt tcgcagagtg taaattgttg aaactaggtt
     2941 gtcataccat gtataccact tgggctttgg tagtagctaa ctgcactaaa tataatataa
     3001 ggagggtttt atggggaaag gccattggaa tcggaaaaga gtttatagca ttcgtaagtt
     3061 tgctgtggga gcttgctcag taatgattgg gacttgtgca gttctattag gaggaaatat
     3121 agctggagaa tctgtagttt atgcggatga aacacttatt actcatactg ctgagaaacc
     3181 taaagaggaa aaaatgatag tagaagaaaa ggctgataaa gctttggaaa ctaaaaatgt
     3241 agttgaaagg acagaacaaa gtgaacctag ttcaactgag gctattgcat ctgagaagaa
     3301 agaagatgaa gccgtaactc caaaagagga aaaagtgtct gctaaactgg aagaaaaagc
     3361 tccaaggata gaatcacaag cttcaagtca agaaaaaccg ctcaaggaag atgctaaagc
     3421 tgtaacaaat gaagaaatga atcaaatgat tgaagacagg aaagtggatt ttaatcaaaa
     3481 ttggtacttt aaactcaatg caaattctaa ggaagccatt aaacctgatg tagacgtatc
     3541 tacgtggaaa aaattagatt taccgtatga ctggagtatc tttaacgatt tcgatcatga
     3601 atctcctgca caaaatgaag gtggacagct caacggtggg gaagcttggt atcgcaagac
     3661 tttcgaacta gatgaaaaag acctcaagaa aaatgttcgc cttacttttg atggcgtcta
     3721 catggattct caagtttatg tcaatggtca gttagtgggg cattatccaa atggttataa
     3781 ccagttctca tacgatatca ccaaatacct tcataaagat ggtcgtgaga atgtgattgc
     3841 tgtccatgca gtcaacaaac agccaagtag ccgttggtat tcaggaagtg gtatctatcg
     3901 tgatgtgact ttacaagtga cagataaggt gcatgttgag aaaaatggga caactatttt
     3961 aacaccaaaa cttgaagaac aacaacatgg caaggttgaa actcatgtga ccagcaaaat
     4021 cgtcaatacg gacgacaaag accatgaact tgtagccgaa tatcaaatcg ttgaacgagg
     4081 tggtcatgct gtaacaggct tagttcgtac agcgagtcgt accttaaaag cacatgaatc
     4141 aacaagccta gatgcgattt tagaagttga aagaccaaaa ctctggaccg ttttaaatga
     4201 caaacctgcc ttgtacgaat tgattacgcg tgtttaccgt gacggtcaat tggttgatgc
     4261 taagaaggat ttgtttggtt accgttacta tcactggact ccaaatgaag gtttctcttt
     4321 gaatggtgaa cgtattaaat tccatggagt atccttgcac cacgaccatg gggcgcttgg
     4381 agcagaagaa aactataaag cagaatatcg ccgtctcaaa caaatgaagg agatgggagt
     4441 taactccatc cgtacaaccc acaaccctgc tagtgagcaa accttgcaaa tcgcagcaga
     4501 actaggttta ctcgttcagg aagaggcctt tgatacttgg tatggtggca agaaacctta
     4561 tgactatgga cgtttctttg aaaaagatgc cactcaccca gaagctcgaa aaggtgaaaa
     4621 atggtctgat tttgacctac gtaccatggt cgaaagaggc aaaaataacc ctgctatctt
     4681 catgtggtca attggtaatg aaataggtga agctaatggt gatgcccact ctttagcaac
     4741 tgttaaacgt ttggtcaagg ttatcaagga tgttgataag actcgctatg ttaccatggg
     4801 agcagataaa ttccgtttcg gtaatggtag cggagggcat gagaaaattg ctgatgaact
     4861 cgatgctgtt ggatttaact attctgaaga taattacaaa acccttagag ctaagcatcc
     4921 caaatggttg atttatggat cagaaacatc ttcagctacc cgtacacgtg gaagttacta
     4981 tcgccctgaa cgtgaattga aacatagcaa tggacctgag cgtaattatg aacagtcaga
     5041 ttatggaaat gatcgtgttg gttgggggaa aacagcaacc gcttcatgga cttttgaccg
     5101 tgacaacgct ggctatgctg gacagtttat ctggacaggt acggactata ttggtgaacc
     5161 tacaccatgg cacaaccaaa atcaaactcc tgttaagagc tcttactttg gtatcgtaga
     5221 tacagccggc attccaaaac atgacttcta tctctaccaa agtcaatggg tttctgttaa
     5281 gaagaaaccg atggtacacc ttcttcctca ctggaactgg gaaaacaaag aattagcatc
     5341 caaagtagct gactcagaag gtaagattcc agttcgtgct tattcgaatg cttctagtgt
     5401 agaattgttc ttgaatggaa aatctcttgg tcttaagact ttcaataaaa aacaaaccag
     5461 cgatgggcag acttaccaag aaggtgcaaa tgctaatgaa ctttatcttg aatggaaagt
     5521 tgcctatcaa ccgggtacct tggaagcaat tgctcgtgat gaatctggca aggaaattgc
     5581 tcgagataag attacgactg ctggtaagcc agcggcagtt cgtcttatta aggaagacca
     5641 tgcgattgca gcagatggaa aagacttgac ttacatctac tatgaaattg ttgacagcca
     5701 ggggaatgtg gttccaactg ctaataatct ggttcgcttc caattgcatg gccaaggtca
     5761 actggtcggt gtagataacg gagaacaagc cagccgtgaa cgctataagg cgcaagcaga
     5821 tggttcttgg attcgtaaag catttaatgg taaaggtgtt gccattgtca aatcaactga
     5881 acaagcaggg aaattcaccc tgactgccca ctctgatctc ttgaaatcga accaagtcac
     5941 tgtctttact ggtaaaaaag aaggacaaga gaagactgtt ttggggacag aagtagcaag
     6001 agttcgtaca ttaattggta aagaaccaaa aatgccgaaa acagtaggtt ttgtatacag
     6061 cgatggtagt cgtgaaaaac ttccagtaac ttggtctcaa gtcgatgtta gtcaagcagg
     6121 agttgtgact gttaaaggta cagcaaatgg acgtgaggta gaggctcatg tcgaggttct
     6181 agcaattgcg aaagaattac caacagttaa acgtattgct ccaaatactg acttgaattc
     6241 tgtagacaaa tctgtttctt atgttttgac tgatggaagt gtacaagagt acgaagtaga
     6301 tagctgggag attacggaag tagataaagc caaactttca gtagctggat cacgtattca
     6361 aatgactggt cagttagctg gagaaactat tcatgcaacc cttgtggtag aagaaggaaa
     6421 tgctgcagca cctgtagtgc caactgttac tgttggaggt gaggcagtaa caggtcttac
     6481 tagtcgacaa ccaatgcaat atcgtactct atcttatggt gcccaactgc cagaagtcac
     6541 agcaagtgct gaaaatgctg atgtgacagt tcttcaagca agcgcagcaa acggcatgcg
     6601 tgcgagcatc tttattcagc ctaaagatgg tggtcctctt caaacctatg caattcaatt
     6661 ccttgaagaa gcgccaaaaa ttgctcactt gagtttgcaa gtggaaaaag ctgacagtct
     6721 caaagaagac caaactgtca aattgtcggt tcgagctcac tatcaagatg gaacgcaagc
     6781 tgtattacca gctgataaag taaccttctc tacaagtggt gaaggggaag tcgcaattcg
     6841 taaaggaatg cttgagttgc ataagccagg agcagtcact ctcaaagcgg aatatgaggg
     6901 agctaaaggc caagttgaac tcactatcca agccaatact gagaagaaga ttgcgcaatc
     6961 tatccgtcct gtaaatgtag tcacagattt gcatcaaaaa cctactcttc caacaacagt
     7021 aacggttgag tatgacaaag gtttccctaa agctcacaaa gtcacttggc aagctattcc
     7081 gaaagaaaaa ctagactcct atcaaacatt tgaagtacta ggtaaagttg aaggaattga
     7141 ccttgaagcg cgtgcaaaag tctctgtaga aggtatcgtt tcagttgaag aagtcagtgt
     7201 gacaactcca atcgcagaag caccacaatt accagaaagt gttcggacat atgattcaaa
     7261 tggtcacgtt tcatcagcta aggttgcatg ggatgcgatt cgtccagagc aatacgctaa
     7321 ggaaggtgtc tttacagtta atggtcgctt agaaggtact caattaacaa ctaaacttca
     7381 tgttcgcgta tctgctcaaa ctgagcaagg tgcaaacatt tctgaccaat ggaccggttc
     7441 agaattgcca cttgcctttg cttcagactc aaatccaagc gacccagttt caaatgttaa
     7501 tgacaagctc atttcctaca ataaccaacc agccaatcgt tggacaaact ggaatcgtac
     7561 taatccagaa gcttcagtcg gtgtcctatt cggagattca ggtattttga gcaaacgttc
     7621 agttgataac ttaagcgttg gcttccatga agaccatgga gttggtgcac cgaagtctta
     7681 tgtgattgag tattatgttg gtaagactgt cccaacagct cctaaaaacc ctagttttgt
     7741 tggtaatgag gaccatgtct ttaatgattc tgccaactgg aaaccagtta ctaatctaaa
     7801 agcccctgct caactcaagg ctggagaaat gaaccacttt agctttgata aagttgaaac
     7861 ctatgctgtt cgtattcgca tggtgagagc agacaacaaa ctaggaacgt ctatcacaga
     7921 ggtacaaatc tttgcgaaac aagttgcggc agccaagcaa ggacaaacaa gaatccaagt
     7981 tgacggtaaa gacttagcaa acttcaaccc tgatttgaca gactactacc ttgagtctgt
     8041 agatggaaaa gttacggcag tcacagcaag tgttagcaac aatggcctcg ctaccgtcgt
     8101 tccaagcgtt cgtgaaggtg agccggttcg tgtcatcgcg aaagctgaaa atggcgacat
     8161 cttaggagaa taccgtctgc acttcactaa ggataagaac ttactttctc ataaaccagt
     8221 tgctgcggtt aaacaagctc gcttgctaca agtaggtcaa gcacttgaat tgccgactaa
     8281 ggttccagtt tacttcacag gtaaagacgg ctacgaaaca aaaaacctga cagttgaatg
     8341 ggaagaagtt ccagcggaaa atctgataaa agcaggtcaa tttaccgttc gaggccatgt
     8401 ccttggtagt gatcttgttg ctgaggtcac tgtacgagtg acagacaaac taggcgaagc
     8461 tctttcagat aaccctaact atgatgaaaa cagtaaccag gcctttgctt cagcaaccaa
     8521 tgatattgac aaaaactctc atgaccgcgt tgactatctc aatgacggag atcattcaga
     8581 aaatcgtcgt tggacaaact ggtctccaac accatcttct aatccagaag tatcagcggg
     8641 tgtgatcttc cgtgaaaatg gtaagattgt agaacggact gttgctcaag ccaaacttca
     8701 cttctttgca gatagtggta cggatgcacc aactaaactc gttttagaac gctatgtcgg
     8761 tccagagttt gaagtgccaa cctactattc aaactaccaa gcctacgacg cagaccatcc
     8821 attcaacaat ccagaaaatt gggaagctgt gccttatcgt gcggataaag acatcgcagc
     8881 tggtgatgaa atcaacgtaa cctttaaagc tgtcaaagcc aaagctatga gatggcgtat
     8941 ggagcgtaaa gcagataaga gcggtgttgc gatgattgag atgaccttcc tggcaccgag
     9001 tgaattgcct caagaaagca cgcaatcgaa gattcttgta gatggaaaag aacttgctga
     9061 tttcgctgaa aatcgtcaag actatcaaat tacctataaa ggtcaacggc caaaagtctc
     9121 agttgaagaa aacaatcaag tagcttcaac tgtggtagat agtggagaag atagccttcc
     9181 agtacttgtt cgcctcgttt cagaaagtgg aaaacaagtc aaggaatacc gtatccagtt
     9241 gactaaggaa aaaccagttt ctgagaagac agttgctgct gtacaagaag atcttccaaa
     9301 actcgaattt gttgaaaaag atttggccta caagacagtt gagaaaaaag attcaacact
     9361 gtatctaggt gaaactcgtg tagaacaaga aggaaaaact ggtaaagaac gtatctttac
     9421 agcgattaat cctgatggaa gtaaggaaga aaaactccgt gaagtggtag aagctccgac
     9481 agaccgcatc gtcttggttg gaaccaaacc agtagctcaa gaagctaaaa aaccacaagt
     9541 gtcagaaaaa gcagatacaa aaccaattga ttcaagtgaa gctagtcaaa ctaataaagc
     9601 ccagttacca aatacaggta gtgcggcaag ccaagcagca gtagcagcag gtttagctct
     9661 tctaggtttg agtgcaggat tagtagttac taaaggtaaa aaagaagact agaaattttg
     9721 ataccttctt tatcattaaa gaccaaagaa aaactcttgt cctaaataga agataaagag
     9781 tctggaacaa aatagttctc aaccacaaaa aagctagata tttccaattg cggaactcta
     9841 gctttttaat tttgagtcgt tctcttattg tatagtagat tgaaactaga gtagtacact
     9901 tctacttcta aaacattgtt agaaatcgat ttgactgtcc ttatcgattt gtcctgttct
     9961 tatttcattt cactatgttt taggaggtta ttggccataa gtaccaatcc catgtcaatt
    10021 ctcacttgac gcttgcctct cagattacat ctcttgtaac ccaaacaagc ctttatctgc
    10081 ccaaagacag gttctacatc aatcttgcgt tgagcgaaaa tctgtctatc ttggggagat
    10141 aaaagcgcct gacattcttt agctttcaag ttttgatagc gttcgttcat atacaatccc
    10201 ttttgagggg ctgattcagg ttcatcagcg tagtaaacct tgatttcctg ttgaaagtct
    10261 gtctgtgttt tctggtactt gatatggtga aaacgatagc accagccatc aggatgtatg
    10321 tagctatcct ccttgtcatt atagtgccaa ttcgctaagt ttttagctga ctgtttatac
    10381 cctctctttt gttccttatc aaacatggca tatttaatca gaaggggagt gatttcttct
    10441 tgaaaataga cttgtatctg ttcttgaagt ttggcggaga atttctctgt cgttttcttc
    10501 cacacaaaac tatacttgtt ggcattggat tcaatcttag ttccgtcaat aaacaaacaa
    10561 tctaaggtca ctaactcttc catttttcaa tttttcgacc agagaaaatc ccttgtgaat
    10621 aggcaaatag aagagtagat acaagcattt tagggtgata agacgggcga ccaaaggcat
    10681 gataggaggt gtagaagtga cgttcctcca aggtattcac cactttttca atagtaaaga
    10741 cgagatggtc ttgtggtaag aaggaactga tttctagtgg taaagttgtt tgatttgtgt
    10801 tatagtgaat atgcatggga tagcctttct aaatggttta ttaagcaatt ctattttacc
    10861 aagactatcg taaccatgca aaaaagcaac ggcaaatccg ttgccttttt tggatataag
    10921 agactattgt cccagactct tttctttgta taaaattgta tagtgttatt gtctatacta
    10981 ttttgtagag aaagcaaaaa tccctagaaa atgcttaggg attcgactat ttcattaaga
    11041 acaattcaac aatcatctct atatacatga taagggttaa taaaaatcct gtacgccaga
    11101 agaatttgat gaatttagga tagtaaaagc tgcgtttttt taaaaggaag aaaaagacga
    11161 gaataatggc taggaacgag agggctagcc ccagtctagg gaggaaatta tgggtaaagg
    11221 ttttagctgt aatcaagtaa tactcaaata ccaagactgg aaaagccaaa tccgcaaagt
    11281 ttcgtcctag tttttttaat ctaaaaagtt tggttaggat aatgcagacg actaaggtca
    11341 gtatcaataa taaaatagat gctaatttca ttaaaatcat acccatattg tatcataaaa
    11401 aaaggctaat ggaaacgaga aacagaggaa tttataggaa agtcaggctt ttgagattgt
    11461 gggtgatttt tgttataatg aaagttataa aatcttatga taccttgaat gattattatc
    11521 gaaaactctt tggagaaaag acttttaaag tccctattga tgcgggattt gactgtccca
    11581 atcgtgatgg aactgtggct catggaggct gtactttttg tacggtttcc ggttctggag
    11641 atgccattgt agccccagat ccgcctatcc gtgagcaatt ttataaggaa attgacttta
    11701 ttcatcgtaa gtggccagat gttcagaagt atctggttta ttttcaaaat tttaccaaca
    11761 cccatgaaaa ggtggaagtt attcgagagc gttatgaaca ggctatcaat gagccaggtg
    11821 tggtaggaat caatattgga acgcgcccag actgtttacc agacgaaacc atcgaatatt
    11881 tggctgagtt atcggagtgc atgcatgtga cggttgaatt gggcttgcag actacttatg
    11941 aagcaacctc tgacctgatt aaccgtgcgc attcttatga attgtaggtg gaaacggtca
    12001 agcgtttgag aaagtatcca aaaattgaga ttgtttccca tttgatcaat ggtttgcctg
    12061 gtgaaaccca tgagatgatg gttgaaaatg tccgccgttg tgtcacggat aacgatattc
    12121 aagggattaa actgcatttg ctccatctta tgacaaatac tcgtatgcaa cgagattacc
    12181 atgagggacg tttacaattg atgagtcagg acgaatatgt cagggtcatc tgtgaccaac
    12241 tggaaattat tcccaaacat atcgtcatcc atcgaattac aggagatgcg cctagggata
    12301 tgctgattgg tcctatgtgg agcctcaata aatgggaagt cctcaacagc attgagatgg
    12361 agatgagacg tcgtggaagt gttcaaggat gcaaggctgt aaaacaggag tttgaaaatg
    12421 aaaagaccac ttgagatggc acatgatttt ttggctgagg tcgtgacaaa agaggatgtc
    12481 gtagtggatg cgactatggg aaatggtcat gacacgcttt ttttagccaa gctagccaag
    12541 caagtctatg cctttgatat tcagaagcaa gccttggaaa agacccaaga gcgtttgcat
    12601 caggctggct tgacaaatgc ccagttaatc ttgcaaggcc atgagacact ggaccagttt
    12661 gtgacaaaag ctaaggcagg gatttttaat ttgggctatt tgccgtcagc tgataagtct
    12721 gtcatcaccc gaccgcagac aacgattgag gcattagaaa agctatgtgg cttacttgtc
    12781 aaaggtggac gaattgctat tatgatttac tatggtcatg aaggaggcga cctcgagaga
    12841 gatgctgtct tggattttgt gatccagttg aaccaacaag agtacacagc tgccatttac
    12901 cgaactttaa accaagtcaa caacccgccg tttttagtga tgattgaaaa attagagaga
    12961 tacagacatg gataaacaat acctacacga aaagctggat gccatgcgcc agaattttgt
    13021 tgaatcaacc taccacgaac gagcggtggg cgtgctagac caagcgcata tgagcaaaaa
    13081 aatgcttaaa atcaagaaaa aattagttgc tcttgaaatg gaacggtgcc agagaaaaat
    13141 tgagcacaaa gactgttcca agattgacca aaaaatcaaa gagcagaagg agatatttga
    13201 atcctgttgt aaaaaagatt aaggaggacg tgcgtggaat tactgattta cctcatccta
    13261 tttttactgg tcttgattgt ctcaagtaca accaataagc tcctaccctt tttgcctctc
    13321 cctttggtgc agattctttt gggaattgtg attggtctct ttttacccaa tactgacttt
    13381 caccttaata cggagttgtt tttggcactg gttatcggcc ccttgctttt ccgagaggct
    13441 gaagaagcag atgttacggc tattttaaaa cactggcgaa tcattgttta tctcatattt
    13501 ccagtgattt ttatctcgac cctgagtttg ggtggcttgg cccatcttct ttggttcagc
    13561 cttcccttgg cagcttgctt ggctgttggg gcagcccttg gtcctacgga cttggtggcc
    13621 tttgcctctc tttcggagcg ttttagcttt cctaagcgcg tgtccaatat tcttaagggc
    13681 gaaggactct tgaatgatgc ttctggtttg gtggcttttc aggtagcttt gacagcttgg
    13741 acaactggag ctttttctct ggggcaagct agcagttcac tcatcttttc aatcctaggc
    13801 ggttttttaa ttggattttt aacagccatg accaaccgct tcctccatac cttcttgcta
    13861 agtgtgcgtg caacggatat tgccagtgaa cttttattag aattgagttt gcctcttgtg
    13921 accttctttc tggcagaaga agttcatgtt tcaggtatta ttgccgtcgt agttgctgga
    13981 attttaaagg caagtcgttt caagaaaatc acgctcctcg aagcccaagt ggatacggtg
    14041 accgagacgg tctggcatac agtgaccttt atgctcaacg gttctgtctt tgtgatttta
    14101 gggatggagc tggaaatgat agcagaacct atcttgacca atccaatcta taatcctcta
    14161 cttttattgc tatctcttat cgcccttacc tttgtcctct ttgtcattcg ttttattatg
    14221 atctatggct attatgccta tagaacccga cgcctcaaga aaaagctaaa taagtatatg
    14281 aaggacatgt ttctcttgac cttttcaggt gttaagggaa cggtgtcgat tgctacgatt
    14341 ctcttgatac caagtaatct agaacaggag tatcctctct tgcttttcct tgttgcaggt
    14401 gtgacgcttg ttagcttttt aacaggtctc ttggtcttgc ctcatctttc tgatgaagag
    14461 gaagaaagca aggattatct catgcatatc gccattttga atgaagtaac gctagagttg
    14521 gaaaaagagt tggaagacac cagaaataaa ctttccctct atgcggctat tgacaattat
    14581 catggacgta ttgaaaatct cattttaagc caagaaaacc aggatgatca agaagactgg
    14641 gctgctttga aactcttgat tcttagtatt gaaagtgatg gtttggaaca ggcctatgaa
    14701 gaggggaata ttagcaatcg tgcttaccga gtttaccaac gttatctgaa aaatatagaa
    14761 caaggaatca atcgtaaact tgcctcaaga ctgacctatt attttcttgt ttccttgagg
    14821 attttacgtt ttctccttca tgaagttttt actcttggaa agaccttccg tagctggaag
    14881 gacaaggagc aaagccgtct ccgtgctctt gattatgacc aaattgcaga gctctatctt
    14941 gccaatacag agatgattat tgaaagtttg gaaaacctga agggagtcta cagacgctct
    15001 ttgattagtt ttatgcagga gtctcgtctt cgagaaacag ctattatcag cagtggtgcc
    15061 tttgtcgaac gggttatcaa tcgtgtcaaa cccaacaata tcgatgaaat gctgagaggc
    15121 tattatctgg agcgcaagtt gattttcgaa tacgaagaaa aacgattaat tacaactaag
    15181 tatgccaaga aattacgaca aaatgtaaat aacttagaga actattcctt gaaggaagct
    15241 gccaataccc tgccgtatga tatggtggaa ttggtaagaa gaaattagtt aatactcttc
    15301 gaaaatctct tcaaaccacg tcagcgtcgc cttggattat atatgtgact gacttcgtca
    15361 gtttcatcta caacctcaaa gcagggcttt gagcaacctg cggctagctt cctagtttgc
    15421 tctttgattt tcattgagta taagattata aatgaaggag tatgacatga aaaagtggtg
    15481 gaaagagctg atagacaagc ctttattaaa agcttttttg cattattatc aagcatcaga
    15541 tagtgagttg accagtgtcg cagtagccta ctattggttg atttcgattt tccccctgct
    15601 tttggtggtg gtcaatatcc tcccctattt tcagattcct gtgggagaat ttctgtgctt
    15661 tatgaaagac gtcctgcccc caagcctcta tgaaggtgtg gaaaaaatag ccagagaagt
    15721 tttgacgcaa ccttcaacag gtttattgag tttttctgtt ttatcggcgt tatggagttt
    15781 ttcaaaatct atgaatttct tgcaaaaagc ttttaacaag gcttatggcg tcgaaaagag
    15841 tcgtggactt atttcccatc agatgctaag tctcctagtc agttttggct tgcagctcct
    15901 ctttgcgttt gccttgtttt tgatcttatt tggtcagatg attttggctt tacttgctca
    15961 ttattggaca aaagatggca ttatctatca ggctttacaa gggttggcag gtcctctgat
    16021 ttacgccctc ctctttgcta tcttggtcat gctttattat tttcttccca atatatctaa
    16081 caggaaaatt agctataccc taccaggcag tgcctttgtt ctcttagtga ttttaggttt
    16141 actaactctg ttctctagtt atctcaatta ctatgtccat catttggtgg atgtccgaat
    16201 tttaggttcc gttcttcttg ttgttatgat gttttggttt atcttgattg ctaaaattgt
    16261 tatcctaggc gcggttatca atgccagtat gcagagtttg agagatccgg tctttaaaaa
    16321 agactaacta tttatccatt acaaaagcgc atagtatcaa aactttatag aaccttgata
    16381 ctatgcgctt ttgtgctttg acagtttttt gtatagtttt tgtccaagat ttctaaatca
    16441 tctgattaaa ttcctatttt cccctatcat tgtccctgtt ttttcgaaaa tggaaggagt
    16501 ataataaatc tatcaataaa atgataggag gaactttatg ggtcatattt tcttttttct
    16561 aagtgtcttt ttggcaggga ttctatcctt cttttctcct tgtatcttac ctttgttacc
    16621 ggtctataca ggagtgttac tagatgataa ggatggtgct caggcttcta gcggcaaatt
    16681 ttcaatctca gttactagtt tattacgaac tctggccttt atagcaggaa tttcctttat
    16741 atttattttg ttgggctatg gagctggttt tttaggcgat ttgctttatg cttcttggtt
    16801 ccaatatctt actggggcaa ttattatcct tcttggtttg caccaaatgg agattctaca
    16861 ctttaagggg ctttataagg aaaagaggct acaactgcaa ggacaggggc aaaatggtaa
    16921 gggctatagt caggcatttt tattgggctt gacctttagt tttgcttgga cgccttgcgt
    16981 ggggccggtt ctggggtctg ttttggcctt ggcggcttca ggtggttcag gagcttggca
    17041 gggagctggt ctcatgttgg tgtatacgct gggcttggcg ctaccattct tgcttctagc
    17101 tctgacctct agttatgttt tgaaacattt ccgaaaactt catccctatc tcggaatcct
    17161 caaaaaagtg ggtggttttc tcattattgt gatgggactc ttggttctgt ttggaaatgc
    17221 ttcaatttta agtcaattat ttgaataaaa tggaaaggaa tatcaatatg aaaaaatggc
    17281 aaacatgtgt tcttggagca ggttcgctcc tttgtttgac ggcttgttca ggcaagtccg
    17341 tgactagtga acaccaaacg aaagatgaaa tgaagacgga gcagacagct agtaaaacaa
    17401 gcgcagctaa agggaaagag gtggctgatt ttgaattgat gggagtagat ggcaagacct
    17461 accgtttatc tgattacaag ggcaagaaag tctatctcaa attctgggct tcttggtgtt
    17521 ccatctgtct ggctagtctt ccagatacgg atgagattgc taaagaagct ggtgatgact
    17581 atgtggtctt gacagtagtg tcaccaggac ataagggaga gcaatctgaa gcggacttta
    17641 agaattggta taagggattg gattataaaa atctcccagt cctagttgac ccatcaggca
    17701 aacttttgga aacttatggt gtccgttctt acccaaccca agcctttata gacaaagaag
    17761 gcaagctggt caaaacacat ccaggattca tggaaaaaga tgcaattttg caaactttga
    17821 aggaattagc ctaggaggtg tcttatgaat gataagttaa aaatcttctt gttgctagga
    17881 gtattttttc tagccataac cggtttctat gttctattga tacgaaatgc agggcagaca
    17941 gatgcctcgc aaattgaaaa ggcggcagtt agccaaggag gaaaagcagt gaaaaaaaca
    18001 gaaattagta aagacgcaga cttgcacgaa atttatctag ctggaggttg tttctgggga
    18061 gtggaggaat atttctcacg cgttcccggg gtgacggatg ccgtttcagg ctatgcaaat
    18121 ggtagaggag aaacaaccaa gtacgaattg attaaccaaa caggtcatgc agaaaccgtc
    18181 catgtcacct atgatgccaa gcaaatttct ctcaaggaaa tcctgcttca ctatttccgc
    18241 attatcaatc caaccagcaa aaataaacaa ggaaatgatg tggggaccca gtaccgtact
    18301 ggtgtttatt acacagatga caaggatttg gaagtgatta accaagtctt tgatgaggtg
    18361 gctaagaaat acgatcaacc tctagcagtt gaaaaggaaa acttgaagaa ttttgtggtg
    18421 gctgaggatt accatcaaga ctatctcaag aaaaatccaa atggctactg ccatatcaat
    18481 gttaatcagg cggcctatcc tgtcattgat gccagcaaat atccaaaacc aagtgatgag
    18541 gaattgaaaa agaccctgtc acctgaggag tatgcagtta cccaggaaaa tcaaacagaa
    18601 cgagctttct caaaccgtta ctgggataaa tttgaatccg gtatctatgt ggatatagca
    18661 actggggaac ctctcttttc atcaaaagac aaatttgagt ctggttgtgg ctggcctagt
    18721 tttacccaac ccatcagtcc agatgttgtc acctacaagg aagataagtc ctacaatatg
    18781 acgcgtatgg aagtgcggag ccgagtagga gattctcacc ttgggcatgt ctttacggat
    18841 ggtccacagg acaagggcgg cttacgttac tgtatcaata gcctctctat ccgctttatt
    18901 cccaaagacc aaatggaaga aaaaggctac gcttatttac tagattatgt tgattaatac
    18961 tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtatgtagg gttactgact
    19021 ccgtcagttt tatctacaac ctcaaagcta tactttgagc tgacttcgtc agttttatct
    19081 acaacctcaa agctatactt tgagctgact tcgtcagttt tatttacaac ctcaaagcgg
    19141 tactttgaga aacctgtggc tatcttccta gtttactttt tgatttttat tgagtataag
    19201 aggtctttcc taagcagtta gaggagaatt ttgctatact gatactagta agtggtaaag
    19261 gagcagagca tgacctacac aatcttaatc gtagaagatg aatatctggt aagacaaggt
    19321 ttgactaaac tggtcaatgt agcagcctac gatatggaaa tcatcggtca ggctgaaaat
    19381 ggaaggcagg cttgggaatt gatccaaaag caggtgccag atatcatttt aaccgatatc
    19441 aacatgcctc atctaaatgg catccagttg gccagtctgg tacgagaaac ctatcctcag
    19501 gttcatttgg tctttttaac aggttacgat gattttgatt atgccttgtc tgctgtcaaa
    19561 ctaggtgtgg acgactacct gctcaaaccc ttttctcgtc aggatattga ggaaatgttg
    19621 gggaaaatca aacaaaaact agacaaggaa gagaaagaag agcagttaca agatttattg
    19681 actaataggt ttgaaggaaa catggcccag aaaatccagt ctcatctggc tgatagccaa
    19741 tttagtttaa agtctttagc cagtgactta ggttttagtc cgacctatct gagttccttg
    19801 attaagaaag agttgggctt gccttttcag gattatctgg tgagagaacg tgttaaacaa
    19861 gccaagctct tgcttttaac tacagatctg aagatttatg agatcgcaga gaaggttggt
    19921 tttgaagata tgaactattt tacccaacgt tttaagcaga ttgcaggtgt gacacctcgt
    19981 cagtttaaga agggagaaga ccgatgaagc gttcttctct tttagttaga atggttattt
    20041 ccatctttct ggtctttctc attctcctag ctctggttgg aactttctac tatcaatcaa
    20101 gttcttcagc cattgaggcc accattgagg gcaacagcca aacgaccatc agccagacta
    20161 gccactttat tcagtcttat atcaaaaaac tagaaaccac ctcgactggt ttgacccagc
    20221 agacggatgt tctggcctat gctgagaatc ccagtcaaga caaggtcgag ggaatccgag
    20281 atttgttttt gaccatcttg aagtcagata aggacttgaa aactgttgtg ctggtgacca
    20341 aatctggtca ggtcatttct acagatgaca gtgtgcagat gaaaacttcc tctgatatga
    20401 tggctgagga ttggtaccaa aaggctattc atcagggagc tatgcctgtt ttgactccag
    20461 ctcgtaaatc agatagtcag tgggtcattt ctgtcactca agaacttgtt gatgcaaggg
    20521 gagccaatct tggtgtgctt cgtttggata tttcttatga aactctggaa gcctatctca
    20581 atcaactcca gttggggcag cagggctttg ccttcattat caatgaaaac catgaatttg
    20641 tctaccatcc tcaacacaca gtttatagtt cgtctagcaa aatggaggct atgaaaccct
    20701 acatcgagac aggtcagggt tatactcctg gtcacaaatc ctacgtcagt caagagaaga
    20761 ttgcaggaac tgattggacg gtacttggcg tgtcatcatt ggaaaagtta gaccaggttc
    20821 ggagtcagct cttgtggacc ttgcttgggg ccagtgtcac atctcttctt gtttgtctct
    20881 gcttagtgtg gttcagtctt aaacgctgga ttgctccttt gaaggatttg agagaaacca
    20941 tgttggaaat tgcttctggt gctcaaaatc ttcgtgccaa ggaagttggt gcctatgaac
    21001 tgagagaagt aactcgccaa tttaatgcca tgttggatca gattgatcag ttgatggtag
    21061 ctattcgtag ccaggaagaa acgacccgtc agtaccaact tcaagccctt tcgagccaga
    21121 ttaatccaca tttcctctat aacactttgg acaccatcat ctggatggct gaatttcatg
    21181 atagtcagcg agtggtgcag gtgaccaagt ccttggcaac ctatttccgc ttggcgctca
    21241 atcaaggcaa ggacttgatt tgtctctctg acgaaatcaa tcatgtccgc cagtatctct
    21301 ttatccagaa acaacgctat ggagataagc tggaatacga aattaatgaa aatgttgcct
    21361 ttgataattt agtcttaccc aagctggtcc tacaacccct tgtagaaaat gctctttacc
    21421 atggcattaa ggaaaaggaa ggtcagggcc atattaaact ttctgtccag aaacaggatt
    21481 cgggattggt catccgtatt gaggatgatg gcgttggctt ccaagatgct ggtgatagta
    21541 gtcaaagtca actcaaacgt gggggagttg gtcttcaaaa tgtcgatcaa cggctcaaac
    21601 ttcattttgg agccaattac catatgaaga ttgattctag acccccaaaa gggacgaaag
    21661 ttgaaatata tataaataga atagaaacta gctaactccc agtcaattct gggagtttta
    21721 tgcgtaattg ggcaaacttt ctaggttgtc tatcttgcta aaaacaagaa aaaacggtat
    21781 gatagaagag tgacaacaga ggtaacagag atgaacgaga cacagattca aagagaaaca
    21841 cgtcaggtag tggaagatgt tttagaaaag accaatttga agcagggggc cctttttgtt
    21901 ttaggtctat cttctagtga ggtgctaggt ggtcagattg ggaaagaatc cagtcaagag
    21961 attggtgagc tgatagtgga gactatcttg gatattctag gtagtagagg tatccattta
    22021 gcagttcaag gttgtgagca tgtcaatcgg gctctcgttg ttgaacgtca ggtggcagag
    22081 cagtttggtc tggaaattgt cagtgtccat cctactcttc atgcaggagg ttcggggcag
    22141 ttggcagcct ttaagtttat gcaggatcca gttgaggttg aatttatcaa ggctcatgct
    22201 ggattggata tcggagacac tgcaattggc atgcatgtca agcatgttca ggttccgatt
    22261 cgccctattt tgagagagat tggtcatgcc catgtaacgg cactggctag tcgtccaaaa
    22321 ttaatcggag gtgcgcgtgc gcactatccg caagatgcta ttagaaagac ctgagaatga
    22381 ataaaggaga taaaagtgtt taaaaaagac cgtttttcaa ttcgtaagat taagggagtt
    22441 gtaggctctg tatttcttgg aagccttttg atggctcctt ctgtagtgga cgcagccacc
    22501 tatcactatg taaataaaga gattatttca caagaagcta aagatttaat tcagacagga
    22561 aagcctgaca ggaatgaagt tgtatatggt ttggtgtatc aaaaagatca gttgcctcaa
    22621 acagggacag aagcatctgt tttgacagct tttggttatc tatcaggtga catcctcaaa
    22681 acgcttggct tggacactgt tttagaagaa acctcagcaa aacctggaga ggtgactgta
    22741 gtcgaagttg agactcctca atcaacaaca aatcaggagc aagctaggac agaaaaccaa
    22801 gtagtagaga cagaggaagc tccaaaagaa gaagcaccta aaacagaaga aagtccaaag
    22861 gaagaaccaa aatcggagat aaaacctact gacgacaccc ttcctaaagt agaagagggg
    22921 aaagaagatt cagcagaacc agctccagtt gaagaagtag gtggagaagt tgagtcaaaa
    22981 ccagaggaaa aagtagcagt taagccagaa agtcaaccat cagacaaacc aacagaggaa
    23041 ccaaaagttg aacaagtagg tgaaccagtc gagccaagtg aagacgaaca ggcaccaacg
    23101 gcaccagttg agccagaaaa gcaaccagaa gctcctgaag aagagaaggc tgtagaggaa
    23161 acaccgaaac cagaagataa aataaagggt attggtacta aagaaccagt tgataaaagt
    23221 gagttaaata atcaaattga taaagctagt tcagtttctc ctactgatta ttctacagca
    23281 agttacaatg atcttggacc tgttttagaa actgcaaaag gtgtctatgc ttcagagcct
    23341 gtaaaacagc ctgaggtaaa tagtgagaca aataaactta aaacggctat tgacgctcta
    23401 aacgttgata aaagtgaatt acaggaacaa ttaagagttg ctgaacaaaa acaacaagct
    23461 gactatagcg ctaaaacttg gagggaattc aaaattgctg aacttcaagc taaagaaatc
    23521 aacaacccaa ctacaccact tcctaaacaa agtgaaatag atgcagctac taaggctctt
    23581 caagacgctc ttcaagctct tgctgtagat aaaactgtat tacaaaacgc tattaacaca
    23641 gctaatagca aacgtgaaga agagtatact gctcagacat ggaaagcgtt aaaagatgct
    23701 cttacagcag tgaatcctgt taatgaagat gaaactgcaa ctcaaagcaa agtagacgaa
    23761 gctactagaa acttagaaga agctatcaat aacctagttc tattaactga aaaaccggta
    23821 ttaacattta ttgagactga taagaaagca ttagaacgtg aagtagttgc taagtattct
    23881 ctagaaaacc aaaataaaac aaaaattaaa tcaatcacag ctactctgaa aaaaggagaa
    23941 acagttgtta gcactgtaga gcttataggc gatgatgtaa ctaatgaaac tataacctct
    24001 gcatttaaga atctagagta ctacaaagaa tacaccctat ctacaactat ggtttacgat
    24061 agaggtgacg gtgatgtaac agaaatctta gataatcaac caatccaact agatcttaaa
    24121 aaagttgagc ttaaaaatat taaacgtaca gatttaatca aatacgaaaa tggaaaagaa
    24181 actaatgaat cactaataac aactgttcct gatgataagc ggaattatta tttaaaaata
    24241 acttcaaaga atcaaaaaac tacattacta gctgttaaaa atatagaaga aactacggtt
    24301 aacggaacac ctgtatataa agttacagca atcgcagaca atttagtctc tagaactgct
    24361 gataataaat ttgaagaaga atacgttcac tatattgaaa aacctaaagt ccacgaagat
    24421 aatgtatatt ataacttcaa agaattagtg gaggctattc aaaacgatcc ttcaaaagaa
    24481 tatcgtctgg gacaatcaat gagcgctaga aatgttgttc ctaatggaaa atcatatatc
    24541 actaaagaat ttacaggaaa acttttaagt tctgaaggaa aacaatttgc tatcactgag
    24601 ttggaacatc cattatttaa tgtgataaca aacgcaacga taaataatgt gaattttgaa
    24661 aatgtagaga tagaacgttc tggtcaagat aatattgcat cattagccaa tactatgaaa
    24721 ggttcttcag ttattacaaa tgtcaaaatt acaggcacac tttcaggtcg taataatgtt
    24781 gctggatttg taaataatat gaatgatgga actcgtattg aaaatgttgc tttctttggc
    24841 aaactacact ctacaagtgg aaatggctct catacagggg gaattgcagg tacaaactat
    24901 agaggaattg ttagaaaagc atatgttgat gctactatta caggaaacaa aacacgcgcc
    24961 agcttgttag ttcctaaagt agattatgga ttaactctag accatcttat tggtacaaaa
    25021 gctctcctaa ctgagtcggt tgtaaaaggt aaaatagatg tttcaaatcc agtagaagtt
    25081 ggagcaatag caagtaagac ttggcctgta ggtacggtaa gtaattctgt cagctatgct
    25141 aagattatcc gtggagagga gttattcggc tctaacgacg ttgatgattc tgattatgct
    25201 agtgctcata taaaagattt atatgcggta gagggatatt cgtcaggtaa tagatcattt
    25261 aggaaatcta aaacatttac taaattaact aaagaacaag ctgatgctaa agttactact
    25321 ttcaatatta ctgctgataa attagaaagt gatctatctc ctcttgcaaa acttaatgaa
    25381 gaaaaagcct attctagtat tcaagattat aacgctgaat ataaccaagc ctataaaaat
    25441 cttgaaaaat taataccatt ctacaataaa gattatattg tatatcaagg taataaatta
    25501 aataaagaac accatctaaa tactaaagaa gttctttctg ttaccgcgat gaacaacaat
    25561 gagtttatca caaacctaga tgaagctaat aaaattattg ttcactatgc ggacggtaca
    25621 aaagattact ttaacttgtc ttctagcagt gaaggtttaa gtaatgtaaa agaatatact
    25681 ataactgact taggaattaa atatacacct aatatcgttc aaaaagataa cactactctt
    25741 gttaatgata taaaatctat tttagaatca gtagagcttc agtctcaaac gatgtatcag
    25801 catctaaatc gattaggtga ctatagagtt aatgcaatca aagatttata tttagaagaa
    25861 agcttcacag atgttaaaga aaacttaaca aacctaatca caaaattagt tcaaaacgaa
    25921 gaacatcaac taaatgattc tccagctgct cgtcaaatga ttcgtgataa agtcgagaaa
    25981 aacaaagcag ctttattact aggtttaact tacctaaatc gttactatgg agttaaattt
    26041 ggtgatgtta atattaaaga attaatgcta ttcaaaccag atttctatgg tgaaaaagtt
    26101 agcgtattag acagattaat tgaaatcggt tctaaagaga acaacattaa aggttcacgt
    26161 acattcgacg cattcggtca agtattggct aaatatacta aatcaggtaa tttagatgca
    26221 tttttaaatt ataatagaca attgttcaca aatatagaca atatgaacga ttggtttatt
    26281 tatgctacag aagaccatgt ctacatcgca gaacgcgctt ctgaggtcga agaaattaaa
    26341 aattctaaac atcgtgcatt cgataattta aaacgaagtc accttagaaa tactatactc
    26401 ccactactga atattgataa agcacatctt tatttaattt caaattataa tgcaattgcc
    26461 tttggtagtg cagagcgatt aggtaaaaaa tcattagaag atattaaaga tatcgttaac
    26521 aaagctgcag atggttatag aaactattat gatttctggt atcgtctagc gtctgataac
    26581 gttaaacaac gactactaag agatgctgtt attcctattt gggaaggtta taacgctcct
    26641 ggtggatggg ttgaaaaata tggccgctat aataccgaca aagtatatac tcctcttaga
    26701 gaattctttg gtcctatgga taagtattat aattataatg gaacaggagc ttatgctgct
    26761 atatatccta actctgatga tattagaact gatgtaaaat atgttcattt agaaatggtt
    26821 ggtgaatacg gtatttcagt ttacacacat gaaacaacac acgtcaacga ccgtgcgatt
    26881 tacttaggtg gctttggaca ccgtgaaggt actgatgctg aagcatatgc tcagggtatg
    26941 ctacaaactc ctgttactgg tagtggattt gatgagtttg gttctttagg tattaatatg
    27001 gtatttaaac gcaaaaatga tgggaatcag tggtatatta cagatccaaa aactctaaaa
    27061 acacgagaag atattaatag atatatgaag ggttataatg acactttaac tcttcttgat
    27121 gaaattgagg ctgaatctgt gatttctcaa caaaataaag atttaaatag tgcatggttc
    27181 aaaaaaatag atagagaata ccgtgataac aataaattaa atcaatggga taaaattcga
    27241 aatctaagtc aagaagagaa aaatgaatta aatattcaat ctgttaatga tttagttgat
    27301 caacaattaa tgactaatcg caatccaggt aatggtatct ataaacccga agcaattagc
    27361 tataacgatc aatcacctta tgtaggtgtt agaatgatga ccggtatcta cggaggtaat
    27421 actagtaaag gtgctcctgg agctgtttca ttcaaacata atgcttttag attatggggt
    27481 tactacggat acgaaaatgg gttcttaggt tatgcttcaa ataaatataa acaacaatct
    27541 aaaacagatg gtgagtctgt tctaagtgat gaatatatta tcaagaaaat atctaacaat
    27601 acatttaata ctattgaaga atttaaaaaa gcttacttca aagaagttaa agataaagca
    27661 acgaaaggat taacaacatt cgaagtaaat ggttcttccg tttcatcata cgatgattta
    27721 ctgacattgt ttaaagaagc tgttaaaaaa gatgccgaaa ctcttaaaca agaagcaaac
    27781 ggtaataaaa cagtatctat gaataataca gttaaattaa aagaagctgt ttataagaaa
    27841 cttcttcaac aaacagatag ctttaaaact tcaatcttta aataattgaa atctctcatc
    27901 tgctttgcgg atgagggttt tcttatttta tgctatactt aaagtatgca tagaaaaaca
    27961 gtgattgatt ttaggacttt gggggagaga tataccttta cccagcctat taaagagttg
    28021 aaaacgagaa atgtagaaga agtggcagat tttctggcac aagtggaaag ctaccaagag
    28081 caaggttatt atgtggtggg gtatgtcagc tacgaggctg cacctgcttt tgaggaaaaa
    28141 ttagcagttc acaaggatcc cctactggga gagtacctgc tttactttac tgttcatgat
    28201 agcgtagaaa cttcccctat tcctctgact tatgaggata ttgatttgcc ctcaaattgg
    28261 caggaagtga cgtctgcagc agactatgaa aaggccattg cccagataca ccatcacttg
    28321 aggcagggag acacctatca ggtcaactac accgtccaac tcaagcaaaa gttaagtgcc
    28381 aatccttttg ccatctacaa tcgtatggtg gtagagcagg aggcgggcta caatgcctat
    28441 gtggaacatg acgagatggc agtgatttcc atgagcccag agctcttttt tgagcaaaat
    28501 gatcgcgagt tgacaacacg accaatgaag gggacgactc agcgtggggt aactgaccaa
    28561 gaagatcttg aacaggccag ttggttggaa caggatccca aaaatcgctc tgaaaatatg
    28621 atgattgtgg acctcttgcg caatgatatg aaccgtattt ctgaagttgg gagcgagcac
    28681 gtggagcgtc tgtgccaggt agagcagtat tcaactgttt ggcagatgac ttcgaccatc
    28741 aagagtcagt tgcgagagga tgtggacctt gttgaaatct tccgctcact ctttccttgt
    28801 ggttccataa cgggtgcacc gaaaattgcg acaatggaga ttatcaagga cttggagcct
    28861 caaccgcgtg gagtctactg tggaacgatt ggtctcttgc ttccaaatgg acgacggatt
    28921 tttaatgtgg ccattcgtac cattcaactt cacaaaggtc aagccattta tggagttggc
    28981 ggagggatta cttgggatag cacatgggaa tctgaatacc gagaggttca tcaaaaggca
    29041 gcagttcttt atcgtaaaca agctcgcttc caactgatta cgacagggga aatcagccag
    29101 aagaacctgc tgtttgaaga tcaacatctg gaaagactga gaaaagctag tcgttatttt
    29161 gcttttcctt ttgatgcaga agacttggga cacaagattg aggaagagtg tcaggattgt
    29221 gaagctaatc gagattaccg cttgcgaatc agccttagca aatctggaga gatagaagtc
    29281 aatcgtcaag tattaacccc tctcagtaca agcttttgtc aggcccaagt ctgccttcag
    29341 gaagctgctt tgaatcaatc ctttacctac tttaaaacca ctcaccgacc gcatttgagc
    29401 ctaggagaac aagagaagat ttaccacaat aagtcaggag aactgcttga aacctctata
    29461 ggaaatttgg ttctgaaaat cgctggaaaa ctctacacac cgcctatccg acttggaatc
    29521 ttgccaggaa tttaccgtca gtatttgcta gaaacaggac aggtagaaga gaaagtcttg
    29581 accttggcag atttagccca agcagaagct atttacggct gtaatgcagt gagaggcttg
    29641 tatgaactaa tccttgagga gaactagatg aaactgatat ttttgcatgg gttagggcag
    29701 tcagcagagt cttggaaaga agttcggaat ctactgacag attatccttc tgaggctatc
    29761 gagttatttc cttctggagt tagtaactat caacaagcta aggagcgagt ttatcagcac
    29821 ctagctcaag agacagaacc ttttgttttg attggattgt ccttaggtgc tgccctggca
    29881 ctagaacttt ccagttacga tttaccaaat cttcgagctt tgattctgtc aggatgcccg
    29941 cttaaattag cagggaatat cctattttat cttcagttgc tgatttttaa actacttccc
    30001 aaaagagtat ttgaaaaaca gggagcagac aaggctctta tggtcggagt ttctgaggag
    30061 ttgaagacac ttgatttaac ggatatagca ggaacttgcc cttatccaac cttactaatt
    30121 tgtggtatca aagataaacc gaatcttagt tctatgagaa gtcttcataa actaatatca
    30181 gaatcccaat ttcagattat cccagatggc cctcatgtct tgaataaggc aaaaccaaag
    30241 gagtttgtag aaaagaccag aagttttctt gaattgctga aataagtttg ataaaataat
    30301 attgaaatcg atatcataat tatgggagaa agaaatgaat aaacgtctat ttttaaaaat
    30361 gagtctggtg acgttgccaa ttttagcctt gttttcacaa cctgtgttag cagaggaaaa
    30421 cattcatttt tcgagttgta aggaagcttg ggctaatgga tattcggatc ttcatgaggg
    30481 agaacctggt tattctgcca agttagaccg cgatcatgat ggtgtggctt gcgaattgaa
    30541 aaatgctcct aagggtgctt ttaaagcaaa acaagcggct acaactcaaa ctgatacaac
    30601 ttcatccaca gcaagtggtt gggttaagca ggacggttct tggtactatt ttgatggaaa
    30661 tggaaatcta gtgaaaaatg catggcaggg aaattattac ctgaaagctg atggtaaaat
    30721 ggcacagagt gaatggattt atgactcttc ttatcaagct tggtattatt tgacatcaga
    30781 tggttcttat gcttacagta catggcaagg aaattactat ctaaaatcgg atggtaaaat
    30841 ggctgtcaat gaatgggttg atggtggacg ttattatgtt ggcgctgacg gagtttggaa
    30901 ggaaggtcaa gcaagtacag cttcttctag taatgatagc aatagtgaat attctgctgc
    30961 tttaggaaag gcaaaaagtt ataattcgtt attccacatg tcaaaaaaac gtatgtatag
    31021 acaattaact tctgattttg ataaattttc aaatgatgca gctcaatatg ccattgatca
    31081 tttagatgat taacagatac tggtaggcga aaaaattcct tataattcat ttacgcaaac
    31141 ctttgcataa gtgaatgtat tttgatatac tagtactgta agcattttca attactacac
    31201 aatgaaaaag gagaatatga tgagtcaaaa gattattggg attgaccttg gtggaacttc
    31261 tatcaaattt gcaatcttaa caacagcagg agaaatccaa ggaaaatggt caatcaagac
    31321 caacattttg gatgagggaa gtcatatcgt tgatgatatg attgagtcta ttcaacatcg
    31381 tttggacttg cttggattgg cagcagcgga cttccaaggc attggaatgg gatcaccagg
    31441 tgtggttgac cgtgacaaag ggactgttat cggtgcctac aacttgaact ggaaaaccct
    31501 tcaaccaatc aaacaaaaga ttgaaaaagc tttgggcatt ccatttttca tcgataatga
    31561 tgccaacgta gcagctcttg gtgagcgctg gatgggtgct ggaaataacc aaccagacgt
    31621 tgtctttatg acactcggta ctggtgttgg tggtggtatt gtcgcagaag gcaaattgct
    31681 tcacggtgtt gctggtgcag caggtgagct tggtcatatc actgttgatt ttgaccaacc
    31741 aattgcatgt acttgtggta aaaaaggctg ccttgagaca gttgcttcag caacagggat
    31801 tgtcaacttg actcgtcgct atgccgatga atacgaaggc gatgcagcct tgaaacgctt
    31861 gattgataat ggagaagaag taactgctaa gactgtcttt gatctcgcaa aagaaggaga
    31921 cgaccttgct ttgattgttt accgtaactt ctcacgttac ttgggaatcg cttgtgctaa
    31981 cattggttca atcctaaacc catcaacaat cgtcatcggt ggtggtgtgt cagctgcggg
    32041 agaattcctt ctacaaggtg ttcaaaaagt ctatgacgaa aatactttcc cacaagtacg
    32101 cacatctact aaattagctc ttgcaactct aggaaatgac gctggagtta tcggagcagc
    32161 atcacttgta ttgcaataag ataatgagag aggaaaatgc taacctaaag ttagtaatgt
    32221 tcctctttta ttttttatgc tatactagtt aggacaatga atgaggtgag agtaaatgac
    32281 aaaagcagat acgattttta aagagaatat tgaacgcatt ctaaaggaag gtgttttctc
    32341 agagcaggct cgtcctaagt acaaggatgg gactgttgct aattccaagt atgtaactgg
    32401 tgccttttcc gagtacgact tatctaaagg agaatttcct atcacaacct tgcgtcccat
    32461 tgcaatcaaa tccgccatca aagaagttct ctggatttac caagaccagt caaatagctt
    32521 agaagtgctt aatgacaagt acaatgttca ctactggaat gactgggaag ttggagacac
    32581 gggaaccatt ggtgagcgct atggtgccgt tgttaagaaa cacgacatta tcaataagct
    32641 tctcaaacag ttggaaacca atccttggaa ccgccgcaat attatttcgc tctgggatta
    32701 ccaagctttc gaagaaacag atgggctgct cccgtgcgcc tttcagacca tgtttgatgt
    32761 tcggcgtgtt gatggggaaa tctatctgga tgcgaccttg acccagcgct ccaatgatat
    32821 gctggtggcc caccacatca acgctatgca gtatgtggct ttgcagatga tgattgccaa
    32881 acattttggc tggaaggttg ggaagttctt ctacttcatc aacaacctcc atatctatga
    32941 taatcaattt gaacaagctc aggaattgct ccgtcgggag ccgtcaaact gccaaccccg
    33001 cttggtttta aatgttcctg atgggactaa tttctttgat atcaaagcag aagattttga
    33061 gttggtggat tatgaccctg ttaagccaca gttgaagttt gacctagcta tttaaaagaa
    33121 tagaaaaaag aagttgagaa taatcccaac ttcttttgtt tcttaacgtg atacgcggcg
    33181 acgagctgct tttttacggt tttcttcgat gaaagctgct ttttgctctt ctggttcgat
    33241 tactttcttt ttaaatgcgt atactgcacc tgcaacggca gcgacagttc ctgcgacacc
    33301 tgttacaaga cctttagcga atcctttagc catgagtctt cctcctttat attctcaatc
    33361 agccagcctc ctcaagaggt cacatttttc tgactgacct ttttgtgtta taataatagt
    33421 aacgaaaaaa tgggaatttt tcaaggaaaa aagatgaaaa caaaaataat tgtgattgtt
    33481 ggaccgactg ctgttggaaa gacggctcta gctattgaag ttgcaaagcg ttttaatggc
    33541 gaagtggtta gtggagatag ccagcaagtc tatcgaggac ttgatattgg gacggccaag
    33601 gctagtccag aagagcaggc agctgttcct catcatttaa tcgatgttag agagataacc
    33661 gagtcttact cggcttttga ttttgtttca gaagctaaga tgactattga ggatattcac
    33721 agccgtggca agctagccat tatcgccggt gggactggac tttatatcca gagcttgcta
    33781 gaaggttacc acctaggtgg ggagactcct catgaggaga ttttagctta tcgagctagt
    33841 ttggagccat attcagatga ggaattagcc catttggtgg agcaagcagg ccttgagatt
    33901 ccccagttta atcgtcgtcg tgctatgcgt gccttagaaa ttgcccattt tggtcaggat
    33961 ttggaaaatc aagagacctt gtatgaaccg ctgattatct gcttggatga tgaacgtagt
    34021 caactttatg agcgtatcaa ccaccgagtg gatttgatgt ttgaggctgg gcttttggat
    34081 gaggccaagt ggctgtttga ccattcccct aatgtacagg ctgctaaagg aattggctat
    34141 aaggaactct ttccttattt ccgtggagag cagaccttgg aggaagctag tgagagtctc
    34201 aaacaggcta ctcgtcgttt tgccaagcgt cagctgacct ggttccgtaa tcgcatgcag
    34261 gtcacctttt atcagattgg agaatctggt gtacaagacc gcattttaag ccagatagag
    34321 gagtttttag atgattgaaa cggagaaaaa agaggagcga gtcctgctga ttggtgtgga
    34381 attgcagggt atggacagtt ttgacctctc catggaagaa ttggctagtt tagcgaaaac
    34441 ggcaggggca gtcgttgtag ataactacag acaaaaacgt gaaaaatatg attccaagac
    34501 cttcgtcggc tctggtaagt tggaagagat tgcgcttatg gtggatgcag aagaaatcac
    34561 tactgtcatc gtcaacaacc gtctgacacc aaggcagaat gtcaatctag aggaagttct
    34621 cggtgttaag gtcattgacc gtatgcagtt gattttggat atctttgcca tgcgggctcg
    34681 aagccatgaa gggaagctcc aagtccacct agcccaactc aaatacctct tgcctcgctt
    34741 ggttggtcag gggattatgc tcagccgtca ggcaggggga attggttccc gtggtcctgg
    34801 tgaaagccaa ctggagctga accgtcgtag cgttcgcaat caaatcacgg atatcgagcg
    34861 ccagctcaag gtggttgaga aaaatcgggc gactgtcaga gaaaaacgtt tggagtctag
    34921 cacctttaag attggtttga ttggttatac caatgctggg aaatcaacta tcatgaacat
    34981 cttgaccagt aagacccagt atgaagcaga tgagctcttt gcgactctgg atgcgacaac
    35041 caagagtatt catctgggag gcaatctcca agtaactttg acagataccg ttggctttat
    35101 ccaagatttg ccgacagagt tggtgtccag tttcaagtca accttggaag aaagcaagca
    35161 tgtggacctt ctggttcatg ttatcgatgc tagcaatcct tatcacgagg agcatgaaaa
    35221 aacggttctc tccatcatga aagacctgga catggaagat attcctcact tgacgcttta
    35281 taataaagcg gatttggtgg aggatttcac gcctacccaa acgccatata ccctcatttc
    35341 tgccaagtct gaggacagtc gtgaaaactt gcaagcatta ttgctagata agattaagga
    35401 aatttttgaa gcatttaccc tgcgagtgcc tttttcaaag tcctacaaga ttcatgattt
    35461 agagagtgtt gcaattctgg aagaacgtga ttatcaggaa gacagcgaag tgattacagg
    35521 ctacatttcc gaaaaaaata aatggaggtt agaagaattt tatgactgat attaaagctt
    35581 tggctctaaa gtatggaggt tatacaagtc tggacaaggt ctatctggat cagcttctag
    35641 ctggtaaaac agagcaggag cagttaacac ttattacacc tccgccaagt gttgttaatg
    35701 cctactttgc agaactctat cagaaaaaga gtcctcaggc tgcgacggat tattttgcag
    35761 aactcagtca ggaactgaat ctttacaata ctgagccaag tttcacccta gaaaataagc
    35821 cttttattcg gcttaatctg tctggtaaat cctttggttt ttgttatgat agtgacggcc
    35881 ttggtcggat tttctctgaa aatgaggaga aaatctcgga tgacttgctc tttgaaattg
    35941 cgcaaatttt cccccatcaa ttagtctttg aagagtctgg taagatttac atgaagcctg
    36001 tcgaggacga ggaagttgtc agcctagaaa gtctcacagc tttgactgat ttggaaagat
    36061 tggctgatgg tcgaaaacgt ctcaaaggct acagccaaga ggatttattg caagaagctg
    36121 ctgctttttc tggcaaacgc tatttccgat cggaaaaccg cacagccatg ttatatattg
    36181 attaattaga aagtatcgaa tggatattca atttttagga acgggggctg gtcagccctc
    36241 taaagctcgc aacgtttcaa gtctcgccct gaaacttttg gatgagatta acgaagtttg
    36301 gctctttgac tgtggagaag gtacgcaaaa tcgcattctg gaaaccacaa ttcgaccacg
    36361 taagatcagc aaaatcttta ttacccatct gcatggagac cacatttttg gtttgccagg
    36421 tttcctttct agccgtgcct ttcaggccaa tgaagagcag acagatttgg aaatctacgg
    36481 acctcaagga atcaagtcat ttgtcttaac cagccttcgt gtgtcaggtt ctcgtctgcc
    36541 ctaccgcatt catttccatg agtttgacca agattctctg ggtaaaattc ttgaaaccga
    36601 taaattcact gtgtatgcag aggagctgga tcacactatt ttctgtgttg gctatcgtgt
    36661 catgcaaaaa gatctagaag ggacgctgga tgctgaaaaa ctcaaggctg ctggtgttcc
    36721 gttcggcccg ctttttggta aaatcaaaaa cggccaggat cttgttttgg aagacggaac
    36781 tgaaatcaag gcagcagact atatctcagc gccacgtcca ggtaagatta tcactatttt
    36841 aggagacact cgaaaaacgg atgccagtgt gcgtctggct gtcaatgcag atgtcctagt
    36901 tcatgagtcc acttatggca agggtgatga aaaaattgct cgtaaccatg gtcactcaac
    36961 taatatgcaa gctgcacaag tagcggtaga agcaggtgcc aaacgcctcc tactcaacca
    37021 tatcagtgcc cgtttcctct caaaagatat tagcaaactc aagaaagacg ctgccacaat
    37081 ttttgaaaat gtccatgtgg tcaaagactt ggaagaagtg gaaatctagc agtcacagaa
    37141 aggataagta tgcctactat tctcattacc ggagctagcg gtggtctagc tcaagaaatg
    37201 gtcaaactcc tgcccaatga ccaactcatc ttgcttggta gaaataagga aaaattagcc
    37261 caactctacg gaaattattc ccatgcagaa ttgattgaaa ttgatattac cgacgattca
    37321 gccctagaag ctctggtaac tgatctttat ctccgctatg gcaagattga tgtcttgatt
    37381 aacaacgctg gttacgggat ttttgaggga tttgaccaga ttgctgataa agatattcac
    37441 cagatgtttg aggtcaatac ctttgccctg atgaatctgt ctcgtcacct tgcggctcgt
    37501 atgaaggaaa gcagcaaagg gcatatcatc aacatcgtca gcatggcagg tctaatagct
    37561 actggcaagt ctagtcttta ctcagcgacc aagtttgcgg ctattggttt ttcaaatgct
    37621 ctgcgactcg aacttatgcc ctatggagtc tatgtgacaa cagtcaatcc aggtccaatc
    37681 cgaacaggat tttttgacca agctgaccca gatggaactt atcttaaatc ggttgaccgc
    37741 ttcctcttag aggcagatgc agtggctaaa aagattgtca agattatagg caaaaataaa
    37801 cgagaactca atctcccgat tttgttgaac ctagcccata agttttatac tctctttccc
    37861 aagctagctg ataagttggt aggggaaact tttaattata agta
//
LOCUS       DBEJZV010000022        35321 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.22, whole genome shotgun sequence.
ACCESSION   DBEJZV010000022 DBEJZV010000000
VERSION     DBEJZV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35321
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.22"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..333
                     /locus_tag="ACL3S0_001346"
     CDS             <1..333
                     /locus_tag="ACL3S0_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR1312248.1"
                     /translation="INVKETSDTANGSLSPSNSGSSVTPMNHNHAPGTTDSVPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
     gene            500..1198
                     /locus_tag="ACL3S0_001347"
     CDS             500..1198
                     /locus_tag="ACL3S0_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1312249.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1195..2247
                     /locus_tag="ACL3S0_001348"
     CDS             1195..2247
                     /locus_tag="ACL3S0_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR1312250.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL3S0_001349"
     CDS             2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL3S0_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGR1312251.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3231..3386
                     /locus_tag="ACL3S0_001350"
                     /pseudo
     CDS             3231..3386
                     /locus_tag="ACL3S0_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            3812..4072
                     /locus_tag="ACL3S0_001351"
     CDS             3812..4072
                     /locus_tag="ACL3S0_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312252.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            4026..4247
                     /locus_tag="ACL3S0_001352"
     CDS             4026..4247
                     /locus_tag="ACL3S0_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312253.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            4566..5495
                     /locus_tag="ACL3S0_001353"
     CDS             4566..5495
                     /locus_tag="ACL3S0_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312254.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5509..6432
                     /locus_tag="ACL3S0_001354"
     CDS             5509..6432
                     /locus_tag="ACL3S0_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1312255.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6690..8165
                     /locus_tag="ACL3S0_001355"
     CDS             6690..8165
                     /locus_tag="ACL3S0_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1312256.1"
                     /translation="MKNWKKYAFTSASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8437..9423
                     /locus_tag="ACL3S0_001356"
     CDS             8437..9423
                     /locus_tag="ACL3S0_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGR1312257.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9545..10405
                     /locus_tag="ACL3S0_001357"
     CDS             9545..10405
                     /locus_tag="ACL3S0_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGR1312258.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(10583..11647)
                     /locus_tag="ACL3S0_001358"
     CDS             complement(10583..11647)
                     /locus_tag="ACL3S0_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGR1312259.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11709..12620)
                     /locus_tag="ACL3S0_001359"
     CDS             complement(11709..12620)
                     /locus_tag="ACL3S0_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGR1312260.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDFITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(12613..13206)
                     /locus_tag="ACL3S0_001360"
     CDS             complement(12613..13206)
                     /locus_tag="ACL3S0_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGR1312261.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            complement(13193..13519)
                     /locus_tag="ACL3S0_001361"
     CDS             complement(13193..13519)
                     /locus_tag="ACL3S0_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR1312262.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            complement(13658..14824)
                     /locus_tag="ACL3S0_001362"
     CDS             complement(13658..14824)
                     /locus_tag="ACL3S0_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGR1312263.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            14882..16039
                     /locus_tag="ACL3S0_001363"
     CDS             14882..16039
                     /locus_tag="ACL3S0_001363"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR1312264.1"
                     /translation="MSSKVSGFQDKNGKVWKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            16081..17931
                     /locus_tag="ACL3S0_001364"
     CDS             16081..17931
                     /locus_tag="ACL3S0_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGR1312265.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQEIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(18017..18187)
                     /locus_tag="ACL3S0_001365"
     CDS             complement(18017..18187)
                     /locus_tag="ACL3S0_001365"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312266.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NIYIRQGDVDVV"
     gene            complement(18237..18869)
                     /locus_tag="ACL3S0_001366"
     CDS             complement(18237..18869)
                     /locus_tag="ACL3S0_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR1312267.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(18891..19763)
                     /gene="sdaAA"
                     /locus_tag="ACL3S0_001367"
     CDS             complement(18891..19763)
                     /gene="sdaAA"
                     /locus_tag="ACL3S0_001367"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGR1312268.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(19772..20443)
                     /gene="sdaAB"
                     /locus_tag="ACL3S0_001368"
     CDS             complement(19772..20443)
                     /gene="sdaAB"
                     /locus_tag="ACL3S0_001368"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGR1312269.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            20685..21257
                     /locus_tag="ACL3S0_001369"
     CDS             20685..21257
                     /locus_tag="ACL3S0_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR1312270.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(21310..21636)
                     /locus_tag="ACL3S0_001370"
                     /pseudo
     CDS             complement(21310..21636)
                     /locus_tag="ACL3S0_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            22055..22342
                     /locus_tag="ACL3S0_001371"
     CDS             22055..22342
                     /locus_tag="ACL3S0_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR1312271.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            22394..24502
                     /locus_tag="ACL3S0_001372"
     CDS             22394..24502
                     /locus_tag="ACL3S0_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR1312272.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            24499..25140
                     /locus_tag="ACL3S0_001373"
     CDS             24499..25140
                     /locus_tag="ACL3S0_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312273.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            25347..26153
                     /locus_tag="ACL3S0_001374"
     CDS             25347..26153
                     /locus_tag="ACL3S0_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1312274.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            26170..27366
                     /locus_tag="ACL3S0_001375"
     CDS             26170..27366
                     /locus_tag="ACL3S0_001375"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HGR1312275.1"
                     /translation="MSKEKVILAYSGGLDTSVAITWLKKDYDVVAVCMDVGEGKDLDF
                     IHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKYPLVSALSRPLISKKLVE
                     IAHQTGATTIAHGCTGKGNDQVRFEVSIAALDLNLKVIAPVREWKWSREEEIYYAKEN
                     GVPVPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITTSPEQAPDMPEYIEI
                     EFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAV
                     TLLTAHKEIEDLTLVREVAHFKPIIENELSNLIYNALWFSSATQALIAYIKETQKVVN
                     GTAKVKLYKGSAQVVARKSPNSLYDENLATYTSADTVDQDAAVGFIKLWGLPTKVHSE
                     VQKSAK"
     gene            27372..28214
                     /gene="argH"
                     /locus_tag="ACL3S0_001376"
     CDS             27372..28214
                     /gene="argH"
                     /locus_tag="ACL3S0_001376"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR1312276.1"
                     /translation="MDREVDVIWLRIQNYGVVALAGTTFPIDRQLSSDLLEFKQPYTN
                     SLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTFTTGSSIMPQ
                     KKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDTVETILNSLD
                     VLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVGRLVLDSIKS
                     AKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEYQIAVAKKAN
                     EAKK"
     gene            complement(28503..29366)
                     /locus_tag="ACL3S0_001377"
     CDS             complement(28503..29366)
                     /locus_tag="ACL3S0_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1312277.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILSHLKK
                     EVEIYYQAKER"
     gene            29832..32051
                     /locus_tag="ACL3S0_001378"
     CDS             29832..32051
                     /locus_tag="ACL3S0_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGR1312278.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDIILSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIIDKTTIVVAHRLSTILR
                     CDKICFLENGTIVEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDIEEVTYG"
     gene            32044..32511
                     /locus_tag="ACL3S0_001379"
     CDS             32044..32511
                     /locus_tag="ACL3S0_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR1312279.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            32508..33860
                     /locus_tag="ACL3S0_001380"
     CDS             32508..33860
                     /locus_tag="ACL3S0_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HGR1312280.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQALQNELLQLQQQGDSPSLSDTTSADDKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNNPTSQAYNIYAQLISEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLVPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            34008..34313
                     /locus_tag="ACL3S0_001381"
     CDS             34008..34313
                     /locus_tag="ACL3S0_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPAR17_0115 family bacteriocin-like peptide"
                     /protein_id="HGR1312281.1"
                     /translation="MELILPNNYVDLEQEEMMYLDGGEPMSISAIVALAITIGGASYS
                     TGYVLGERVYYSGYKNSDYQKNKWGIRGAMLAAFGAIGAVVMLGFENRYYALVTGRG"
     gene            34647..35000
                     /locus_tag="ACL3S0_001382"
     CDS             34647..35000
                     /locus_tag="ACL3S0_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR1312282.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGAYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLAGAAGRIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            34997..>35321
                     /locus_tag="ACL3S0_001383"
     CDS             34997..>35321
                     /locus_tag="ACL3S0_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312283.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFD"
BASE COUNT        10910 a         6127 c         7568 g        10716 t
ORIGIN      
        1 ataaatgtta aagaaacatc agacacagca aatggttcat tatcaccttc taactctggt
       61 tctagcgtga ctccgatgaa tcacaatcat gctccaggta ctacagatag cgtgcctgct
      121 gacaccatga caagttctac caacacgatg gcaggtgaaa acatggctgc ttctgctaac
      181 aagatgtctg atacgatgat gtcagaggat aaagctatgc taccaaatac tggtgagact
      241 caaacatcaa tggcaagtat tggtttcctt gggcttgcgc ttgcaggttt actcggtggt
      301 ctaggtttga aaaacaaaaa agaagaaaac taatcagcta aggaaataaa tgatggatag
      361 tgggctgact aagattagtt taacaactca atcagcaatc aggactttct ttcaatagca
      421 gattaaaatc atcgtaaaac aataaaaata gtgttatact taaagcagta tagcactgtt
      481 tttatcaaag gagagacaga tgggaaagac aattttactc gttgacgacg aggtagaaat
      541 cacagatatt catcagagat acttaattca ggcaggttat caggtcttgg tagcccatga
      601 tggactggaa gcgctagagc tgttcaagaa aaaaccgatt gatttgatta tcacagatgt
      661 catgatgcct cggatggatg gttatgattt aatcagtgag gttcaatact tatcaccaga
      721 gcagcctttc ctatttatta ctgctaagac cagtgaacag gacaagattt acggcctgag
      781 cttgggagca gatgatttta ttgctaagcc ttttagccca cgtgagctgg ttttgcgtgt
      841 ccacaatatt ttgcgccgcc ttcatcgtgg gggcgaaaca gagctgattt cccttggcaa
      901 tctaaaaatg aatcatagta gtcatgaagt tcaaatagga gaagaaatgc tggatttaac
      961 tgttaaatca tttgaattgc tgtggatttt agctagcaat ccagagcgag ttttctccaa
     1021 gacagacctc tatgaaaaga tctggaaaga agactacgtg gatgacacca ataccttgaa
     1081 tgtgcatatc catgctcttc gacaggagct ggcaaaatat agtagtgacc aaactcccac
     1141 tattaagaca gtttgggggt tgggatataa gatagagaaa ccgagaggac aaacatgaaa
     1201 ctaaaaagtt atattttggt tggatatatt atttcaaccc tcttaaccat tttggttgtt
     1261 ttttgggctg ttcaaaaaat gctgattgcg aaaggcgaga tttacttttt gcttgggatg
     1321 accatcgttg ccagccttgt cggtgctggg attagtctct ttctcctatt gccagtcttt
     1381 acgtcgttgg gcaaactcaa ggagcatgcc aagcgggtag cggccaagga ttttccttca
     1441 aatttggagg ttcaaggtcc tgtagaattt cagcaattag ggcaaacttt taatgagatg
     1501 tcccatgatt tgcaggtaag ctttgattcc ttggaagaaa gcgaacgaga aaagggcttg
     1561 atgattgctc agttgtcgca tgatattaag acccctatca cttcgatcca agcgacggta
     1621 gaagggattt tggatgggat tatcaaggag tcggagcaag ctcattatct agcaaccatt
     1681 ggacgccaga cggagaggct caataaactg gttgaggagt tgaatttttt gaccctaaac
     1741 acagctagaa atcaggtgga aactaccagt aaagacagta tttttctgga caagctctta
     1801 attgagtgca tgagtgaatt tcagtttttg attgagcagg agagaagaga tgtccacttg
     1861 caggtaatcc cagagtctgc ccggattgag ggagattatg ctaagctttc tcgtatcttg
     1921 gtgaatctgg tcgataacgc ttttaaatat tctgctccag gaaccaagct ggaagtggtg
     1981 actaagctgg agaagggcca gctttcaatc agtgtgaccg atgaagggca gggcattgcc
     2041 ccagaggatt tggaaaatat tttcaaacgc ctttatcgtg tcgaaacttc gcgtaacatg
     2101 aagacaggtg gtcatggatt aggacttgcg attgcgcgtg aattggccca tcaattgggt
     2161 ggggaaatca cagtcagcag ccagtacggt ctaggaagta cctttaccct cgttctcaat
     2221 ctctctggta gtgaaaataa agcctaaaac ccctttacaa atccagctat tcatggtaaa
     2281 atggattttg tgtgaaatat cagcaggaaa gcatgaagct cgtcaacagg tgtcttatga
     2341 caagtaacct tggctgttta ggcgaagggc atctgcacga atcagggctt tctaagtgac
     2401 tatttccacc gaaatattat ttatatcagg aggacattca tatgtcacgt tatacaggac
     2461 catcttggaa acaagctcgt cgccttggcc tttcacttac aggtacaggt aaagaattgg
     2521 cacgtcgtaa ctacgtacca ggacaacacg gaccaaacaa ccgttctaaa ttgtcagaat
     2581 atggtttgca attggctgaa aaacaaaaac ttcgtttcac ttacggtgta ggtgaaaaac
     2641 aattccgtaa cttgttcgta caagctacaa aaatcaaagg cggaatccta ggtttcaact
     2701 ttatgcttct tttggaacgt cgtttggata acgttgttta ccgtcttggt ctcgcgacta
     2761 ctcgtcgtca agctcgtcaa ttcgtaaacc acggtcacat ccttgttgac gggaaacgcg
     2821 ttgatatccc atcataccgc gtaactccag gtcaagtaat ctcagttcgt gaaaaatcat
     2881 tgaaagttcc agcaatcctt gaagcagtag aagctactct tggacgtcca gcattcgtat
     2941 cattcgacgc tgaaaagttg gaaggttcat tgactcgctt gccagaacgc gacgaaatca
     3001 acccagaaat caacgaagca cttgtcgttg aattctacaa caaaatgttg taatatttta
     3061 ttgaataaga taggctttga tattaagcac tttgggacgt tctcccttag tgcttttttg
     3121 atttctctta gtatccagct ataatcgttg agacataact agaccgatat agtccaaagt
     3181 gatatagtaa aatgaaccaa aaatagtaca caatgtggta taatcctttt atggcatatt
     3241 caatagattt tcgtaaaaaa gttctctctt attgtgagcg aacaggtagt ataacagaag
     3301 catcacacgt tttccaaatc tcacgtaata ccatttatgg ctggttaaag ctaaaagaga
     3361 aaacaggaga gctaaaccac caagtatagt gtattgaatc tataacagta caccttggct
     3421 gctaaaatat ttctataaat taatttgact ttcctgatag agttgttcac atcttatttc
     3481 aaatcactat aaaagctcta taatctcttt ataagatttg cccatcagac gaaatataat
     3541 ggattgaaac tagaatagta cacctctact tctaaaacat tgttagaaat cgatttgact
     3601 ttcctgatcg atttgtcctg ttcttgtttc attttactat agaacgattt gaaggcgttt
     3661 atgatattta gctgtacgag agtcttttaa aagtgttttg atggtttgga tttcttcttt
     3721 agttgatttc atatcactgt tatataatgc tttttgattt tagtctagta ttagtaagca
     3781 gactcaaacc ttagaaaatc ttttgagatc attgacaggt gtatcgaatc ctaccacaga
     3841 ttcagcacgt ctggttttgg cagaggctaa gaaagctttt gcagatgata gtttgacaga
     3901 gcaaggttta cgtgatatct tgcaaacagt caaagatgcc attgcttccc tagagtccat
     3961 taaggaaagc cagtcagcaa ctaaggatgg aggacaaaca gcgggcaaag aaacagcagg
     4021 agaagatgag tctgcaaatc aaactcaaga aattagccaa ggaattaagt aaacttctta
     4081 aagactcaaa ccttgaaaca gtagataagg atgtccttga aaactctcaa aaagaacttc
     4141 aaaaagcagt tttgttcttg gcagatgaaa aaggctctga gcatactgaa gcagaggtga
     4201 ttgataatct taaagaggtt attgctaagt tgaaagcaaa cgcctaataa catattaaaa
     4261 atctccagat taggaactat cgctgagttc cctagtctgg agatttttca gtataccccg
     4321 ttgttggatg cttataacag agtgacgcca tcactgggct aatagagata aaataaacaa
     4381 ttgatttagg acatttgttt gatagtggtg ataaagtttt aaatctgcta cataatttgt
     4441 ggagtttttt ctataattag gagtttaacc taacctgcaa ataggagtat actaataatg
     4501 taatcgttat caaaagtcta aaaaagaatt tttagatgga tatcaaaata aaaagggagg
     4561 aaattatgaa aaagttttca aaaacattga gagacaactg gatctttctc ttgatggttt
     4621 tgccaggggc actctggttg attctattct tttacattcc agtatttggg aacgtggttg
     4681 ccttcaaaga ctaccacatg accagtaatg gtttcataga tagtatcata aatagtaaat
     4741 gggtcggact cgataatttc agattcttat ttagttcaag agacgccttt attatcacac
     4801 gaaataccgt cctctacaat cttggcttta tctttctagg tttagttgta tctgtaggga
     4861 ttgccattat cctcagcgag ctccgttcta agagaatggt gaagattttc caaacttcta
     4921 tgttgttccc ttacttcttg tcttgggtta tcatcagttt ctttacagat gccttcctaa
     4981 atattgataa aggggtgttc aatcatctat tggaaagtct tggtctcaaa gaagtcaatt
     5041 tctacgctga cctgggcatc tggccctatc tcctactttt cctaggtatt tggaaaggtt
     5101 ttggatatag cagtgtcatg tactatgcga cgatcatggg aattgatcca acctactacg
     5161 aagcagcgac agtggacgga gctagcaagt ggcaacgtat tcgcaacgta accattcctc
     5221 agttgactcc gcttgtaact gtattgacca tccttgcagt cggaaatatc ttccgcgcag
     5281 acttcggtct cttctatcaa atcccacaca atgctggtca gctttacaat gtaaccaacg
     5341 ttttggacgt atatgttttt aatggtttga ctcagacagc agatatcggt atggctgcag
     5401 cagccggtct ttaccaatcc gttgttggtt tgattctggt tatcctatca aacttgcttg
     5461 caagacgagt cgatccaaac tcagctttgt tctagaaagg aggagaatat ggcaaaaaag
     5521 aaaattaaaa aagaaaaaat tgataatgtc ggcattcact ccttcagtaa gaaagcagat
     5581 atcttcttca gtatcatttc gggtttgatt gccctctctt gtatcctacc ttttgtattc
     5641 gttatcatta tttcagtgac agacgagaaa agcctcctcc aatacggcta tagcttcttc
     5701 ccatcccaat ttggcttaga cggttttgag tttttggcac agtttaagga taaaatccta
     5761 caagccctct tcatctctgt ctttgtaacc gtagttggga cattgacaaa tgtctttatc
     5821 acaacaacct atgcctacgc tatttcacgg acaaccttta agtatcgcag attctttacc
     5881 atcttcgttc tgctcagtat gttgttcaac gctggtttgg taccaggtta tatcatggtg
     5941 actcgtgtgc ttcagcttgg ggatactgtt tgggccttga ttgttccaat gcttctctca
     6001 ccatttaaca tcatcttgat gcgttccttc ttcaagaaga ccattccaga agccattcta
     6061 gaatcggctc gtatcgatgg tgccagtgaa gcccggattt tcttccaaat ctgtttgcca
     6121 ttgtcactac caggtatcgc aaccatcacg ctcttaacag ctcttggttt ctggaatgac
     6181 tggttcaacg cccttcttta catcaagagt gacaacttgt atccattgca atatttgctc
     6241 atgcaaatcc aacaaaatat ggactacatt gccaaagcgg tcggcttgac tggtcaactg
     6301 ggagttgctc taccgaaaga aacaggtcgt atggccatgg ttgtggttgc aacccttcca
     6361 atcgcgattt tgtatccatt tttccaacgc tactttgtaa aaggtttgac tatcggtggt
     6421 gtgaaagaat agtgcttatt gagaaataac atttctcagt tcccaacttc ccttgtgtga
     6481 agttaatact cttcgaaaat caaattcaaa ccgtgtcaac gtcgccttgc cgtagatata
     6541 tgtaactgac ttcgtcagtc ttatctacaa cctcaaagca gtgctttgag cagcctgcgg
     6601 ctagttttct agtttgctct ttgattttca ttgagtataa gatcattaca ttgtttataa
     6661 gtttaaaaat aaaaaaagga gtttttatca tgaaaaactg gaaaaaatat gcttttacat
     6721 ctgctagtgt agtcgctctg gctgcaggtc ttgctgcttg tggaaatttg acaggtaaca
     6781 gcaaaaaagc tgctgattca ggtgacaaac ctgttatcaa aatgtaccaa atcggtgaca
     6841 aaccagacaa cttggatgaa ttgttagcaa atgccaacaa aatcattgaa gaaaaagttg
     6901 gtgccaaatt ggatatccaa taccttggct ggggtgacta tggtaagaaa atgtcagtta
     6961 tcacatcatc tggtgaaaac tatgatattg cctttgcaga taactatatt gtaaatgctc
     7021 aaaaaggtgc ttacgctgac ttgacagaat tgtacaaaaa agaaggtaaa gacctttaca
     7081 aagcacttga cccagcttac atcaagggta atactgtaaa tggtaagatt tacgctgttc
     7141 cagttgcagc caacgttgca tcatctcaaa actttgcctt caacggaact ctccttgcta
     7201 aatatggtat cgatatttca ggtgttactt cttacgaaac tcttgagcca gtcttgaaac
     7261 aaattaaaga aaaagctcca gacgtagtac catttgctat tggtaaagtt ttcatcccat
     7321 ctgataactt tgactaccca gtagcaaacg gtcttccatt cgttatcgac cttgaaggcg
     7381 atactactaa agttgtaaac cgttacgaag tgcctcgttt caaagaacac ttgaagactc
     7441 ttcacaaatt ctatgaagct ggctacattc caaaagacgt cgcaacaagc gatacttcct
     7501 ttgaccttca acaagatact tggttcgttc gtgaagaaac agtaggacca gctgactacg
     7561 gtaacagctt gctttcacgt gttgccaaca aagatatcca aatcaaacca attactaact
     7621 tcatcaagaa aaaccaaaca acacaagttg ctaactttgt catctcaaac aactctaaga
     7681 acaaagaaaa atcaatggaa atcttgaacc tcttgaatac gaatccagaa ctcttgaacg
     7741 gtcttgttta cggtccagaa ggcaagaact gggaaaaaat tgaaggtaaa gaaaaccgtg
     7801 ttcgcgttct tgatggctac aaaggaaaca ctcacatggg tggatggaac actggtaaca
     7861 actggatcct ttacatcaac gaaaacgtta cagaccaaca aatcgaaaat tctaagaaag
     7921 aattggcaga agctaaagaa tctccagcgc ttggatttat cttcaatact gacaatgtga
     7981 aatctgaaat ctcagctatt gctaacacaa tgcaacaatt tgatacagct atcaacactg
     8041 gtactgtaga cccagataaa gctattccag aattgatgga aaaattgaaa tctgaaggtg
     8101 cctacgaaaa agtattgaac gaaatgcaaa aacaatacga tgaattcttg aaaaacaaaa
     8161 aataatcagc taaattgatt tcgtgtattc attcctaact cctaaaataa gaatcactgc
     8221 tttcctcagg ttggtctggg gagggcagtg gtttttttgg cacaaggata tagatatcca
     8281 tgttttctct tgtccttatt ttaaccattc aggaaatttc gagaaccctc tacaatttcc
     8341 agtcaaataa attgcattcg ttttctcaag caggtatact agtatggata aataaaaaat
     8401 ttagaaaatt taagaataga aaagagaaca aatcttatgg caaaagatat tcgtgtctta
     8461 ctttactacc tttatactcc aattgaaaat gcagagcaat ttgctgcaga ccacttggct
     8521 ttctgtaaat caatcggcct taaaggccgt atcctagtcg ctgacgaggg aattaacgga
     8581 acagtttcag gtgactatga aacaactcaa aaatacatgg actacgttca cagccttcca
     8641 ggaatggaag aactctggtt caagattgac gaagaaagtg aacaagcctt caagaagatg
     8701 tttgttcgct acaagaaaga aattgtccac cttggtttgg aagacaacga ctttgacaat
     8761 gacatcaacc cacttgaaac aacaggtgct tacttgtctc caaaagagtt caaagaagcg
     8821 cttcttgata aagataccgt tgtccttgac acacgtaatg attatgagta tgacctagga
     8881 catttccgtg gggctattcg cccagatatt cgcaacttcc gtgagttacc acaatgggtc
     8941 cgtgataaca aggaaaaatt catggacaag cgtgtcgtgg tttactgtac aggtggcgtt
     9001 cgctgtgaga aattctcagg ctggatggtc cgtgaaggct acaaagatgt cggccaattg
     9061 cacggaggaa tcgcaactta cggtaaagac ccagaagttc aaggtgagct ttgggatgga
     9121 aaaatgtacg tatttgacga gcgtatcgcc gttgatgtca accatgtcaa cccaaccatc
     9181 gtagggaaag actggtttga tggaacacca tgtgaacgtt atgtcaactg tggaaatccc
     9241 ttctgtaacc gtcgtatctt gacatcagaa gaaaatgaag acaagtacct tcgtggatgc
     9301 tcacacgagt gccgtgttca cccacgtaac cgctatgttt caaaaaatga attgacacaa
     9361 gctgaagtga ttgagcgcct agccgctatc ggtgaaagct tggatcaagc agctactgta
     9421 taagatcaaa cagtcctcag gggctgtttt tctatgcttt gtactcaaaa atctaaagtt
     9481 tgtttctgta tctttcagaa aaataaggta tactgtatgt aaacgatttc aaaggagtcc
     9541 agttatggca aaaacatttt ttattccaaa taaacagagc attttaggag aacaagagat
     9601 tttgaatgcc aagtcgatct tggccttgct agacggtttg gagtcacata gctatgatgt
     9661 agtctatctc cgtcagcctc ttaatcgtct cgaatatatc gagtgtgcga tagtggggca
     9721 atcacaattt ctctttaagg tcagttatgc tgatggtcaa aaggcttacc gtgtcgatct
     9781 tcctgaccta ctaacaaaga cagactggca gattatcaag tcatttttag atgctttgct
     9841 tgcttataca gggactgata ttgaagggct agatggtttt gattttgaag cttatttcca
     9901 agcaagtatt caagcctatc tagcagaccc tgtagctcgt tttacgattt gccaaggaat
     9961 ttttaatcct attttcttta gtcgtgagaa cttgaaaagc tttttagagg cagatggctt
    10021 ggctcagttt gaagcgcgtg tgcgtgcggt tcaagagaca gatgcctact ttgcgagagt
    10081 ttccttctat caggatggag aaggaaaagt gcatggcgtt taccatctag ctcaaggagt
    10141 caagacagtt ttaccgagag aaccgtttgt tcctgcagcc tatattgagc aattggtgga
    10201 taaggaagtg cagtgggaga ttgacttggt tcaaatcaca ggagatggct ctaaaccaga
    10261 agactatgaa gccattgccc gcttggacta tgcaaaattc ttagaggtat tacccctatc
    10321 tttttaccac caactagacg ccaatcaaat agaagtgcaa cccatattag acaaagattt
    10381 taaagcatta gcacaagaag agtaaagcag aagcaggtca atcgacttgc ttttttgaca
    10441 tagaaaaaat cctgccaagg atgacaggat tgctactcaa tgaaaatcaa agagcaaact
    10501 aggaagctag ccgcaggctg tacttgagta cggtaaggcg aagctgacgt ggtttgaatt
    10561 tgattttcga agagtatgaa gtttaaagaa aggccaagat acgaagataa tctccaatca
    10621 gtgccacttc agctacaaag aagaggagga taataactcc gttcacaagg acagacaaga
    10681 ataattgata gaaggagtcg gtttcacttg cttgacttgg tcttgtaatg atatggagac
    10741 tggcaagcag aatgattcca atgctaatca cacacaagag agctgtaaat cgtaggctat
    10801 caaagaaagc aaagaaacta gcaatagcag tgaggaagat tggaattgcc aagagttgac
    10861 tatattgttg gagaaccttg tctagcgtcc agtccttttc ctggtggata aatcgtctca
    10921 caacgaaact acccaagagg aatgaaaaga agaagagtgt tgtcgctact aggatagaga
    10981 cgatagaaaa aagagttaaa ggagctagct gctcagggaa gcgactgtta atgcttgcta
    11041 tatgtccata gtaagcatgt ttgatgtgat agatactaaa gaaaaaggaa gatgcagaaa
    11101 acagaatgag caagagaaag gctgtgtaac tgtgtgtgat acttgtttcc aacttacttg
    11161 taggagattt gatcgcttcc actagccaag accaaaaatc aagcacttgc tctttccatt
    11221 tatccctaga ttttggagct tggtcgggga tataaggact ttctaaagat ttactgataa
    11281 gaagtggctc tttcgtggtt gctttttgct gaggaagagc ttcttggctc tcttcagcta
    11341 tagtgacttt ttctgtttct ttagaaaggt ctgactcttc ttcagtagaa ttagatgcct
    11401 tcttttcttc tatttctgtt ctcgcttcac cgacttcagg agtttcaatt ttctcttctt
    11461 gctggctttc cagttcgact tcagcttgag agacttcctc ctctacttga gtattttttc
    11521 caattggtgt atcgaaatcg gctatcgttt cttcagcctt gtctgcaacc tcttgagctt
    11581 gctcttcagg cttgttcttg cttgttgttt ttacaaaatc attactttca aaccattctt
    11641 gtttcatggt agaacctcct tttggttaga taaatatgct tccatagtag cagatgtaag
    11701 cgtttttgtc aacgtctgct tggtgtggat attagatcaa tattatcatc agatctcgca
    11761 atgagttgat ccttgacatc ggttttttca gttttgtaag ggttgcttaa ttccgtacct
    11821 cttgattcag gcttttctct tgtgaattgg aagatagaac cgtagttact tgagatgtcc
    11881 cagttaattc gttggctttc tttctggtct aggatgattc tgagataatc tttggcagtc
    11941 agttcaacct taccatggac ttggatattt tcagcgtgga agtgattatc tgttgactct
    12001 agctgactat ctgtaagaac tgtatcaaag atattaacga tattgggcgt tgtgagttta
    12061 ctgtttttga tacgacttcc ttcaattcgg aggatatagc tgtttgtatt gagggtcgca
    12121 ttttcaaggc tagcatttat gatggtggtt tgtccgcgat tggctgagat gttgatccct
    12181 tttagagttc tcccttttgg tagtcggaga ataacttctt caaaacgact agagtagcta
    12241 cttgcgatat gaagaatccc accaattcca gaagagagaa acggagtttc agacagtttc
    12301 ttatcagtga gactcagagt tctatcgttc tgattggtga taaaatcatg gtgagcagaa
    12361 agagatggat ggtaagaaat gtggatttga tcatcgaaag agtctgtgat ggtgagcgtg
    12421 tgttggtgga gagtaatttc taggttttcg acttccttgc caaaggttag cttttccgta
    12481 cggctatcat agacaggttc tttggacatg gaaagtaggc tcttaatccc gtcagattgg
    12541 atacctacaa aaagcaggat aaagccgata acggtagtca ccacaccaaa gatgagaaat
    12601 ccttttgtcc atttacgcat gctgattacc tctctttcct tttttaagaa caaattgtac
    12661 cagacgaaca atgagtagac cgaagaagcg agctacatag gaaatgccaa gtaaaactag
    12721 cgaagaagca ccgatagcca gtaaaccaga accaaaaatc aagataaagg ctgatttggc
    12781 ttgggcgagg atagtgaaac tttcaactaa aaataggaat ccgccgatga tacccagtat
    12841 ggaaactgca aagaaagcca gaatgacagt caaagcggct acaaggattg cgaacagggt
    12901 cacgaggatg gcgattccca gaggaatgcc gataggtgct gcaaggaggg ctaacaaggc
    12961 gatatgtaaa atttgtcggt tatttttttg agcgggtgct tcattgattt ttttatcgag
    13021 aagattggat agaacttcgt gggccgcttc tttgggagtt cccaaactag cgatgagttc
    13081 ttcttctcct tcgactccag catcgtcaaa gagctctctg aaatagtcca tggcttcgat
    13141 acggtcagct tcaggtagtt tcttgagata gagttctagc tgagtcaggt attcagttct
    13201 tgtcatggcg gatactccct tctatgatgc cattgatggt gtctgtatag agtgtccatt
    13261 catcttttag ggtcaagagc tgctctatac caccgtttgt caaggagtag tatttgcgca
    13321 tgcgaccttg gaactctcta gaataggttg tcagaaagct attgccttcc aattttttga
    13381 gaatgggata gagtgtggat tctttgatat tagcgatcag cttaatggtt tggctaatct
    13441 cataaccata agaatcaccc tgctccagta cagccaagat gagaaattca atcaaggcag
    13501 aggatgttgg aaagtacatg ggaaacctcc ttttctaatg tgtaagattt ttatatataa
    13561 tttttctaca catacattgt acatctaaaa gaaagccctg tcaagagaaa tgtgtaaaat
    13621 ttttatatat aaaaaacttc tagctaaaac tagaagttta aaggatctta tccgctctgt
    13681 ccactgtaaa gagggccaca gtcatcagga tatagatgag caagagggca gctacagctg
    13741 gtacccaaga gtggaacagg tcaaaactgt aaccaaagag ggttggccca aaggctgcta
    13801 ggatatagcc tcctgtttga gataggccgg acaattgggc tgtcttttca ggggcgcttg
    13861 tcttgagtga aaagttgacc atgagataag ggaagagggc gctggttgcg gttccgatga
    13921 ggagatggat ggtaagccag taaatgaaat tattgattgg gaaaaagagc atggaaatgc
    13981 cgaccacacc agctagtgaa accagagtga gcatgagctg acggttgcga gtagataaac
    14041 tggttgtcag gcttgggatg gtcattgaaa aaggaatgct aatcagagat aagatagaag
    14101 tcagcaagcc agcttcgtga ctggatagac ctgcatggat agacatggta ggtaaccagg
    14161 tcatgacggt gtaaaagatc aaggattgaa aacctgaaaa gataataatt gcccaaacct
    14221 gtttattacg catgaccttt atttgacttt tttgtttggt ttgtggagct agtctatgat
    14281 tatagcggtg atttgggagc cagaccaaaa aagttgctag acagagtaac gtgaggagaa
    14341 ggataagtcc tttccaagaa ctggcttgtg taatgggcac agctagatag gaagccagag
    14401 ccgttgcaat ccccatagac gttacatata aggtggtcag aaaaccaatt ttctttggtt
    14461 gattggcttg gataagacta ggaagcagga cattgatgac tgcgacactt gccccaacca
    14521 tcaaggttcc tagatagagc aggggcagat tgattagtcg aataagtgag ccgatggtca
    14581 agaagaagag gctgtaggtg aagagatgct ccaagccgat tttctgagcc agtcgggtag
    14641 aaaatggtga aaagagggta aacataagga gaggcaggct ggtcaagaca ccaagcgaac
    14701 taacttctac ctccagacct tgcgaaatat ttcccaaaat aatgggtaaa acagtaaaag
    14761 gagttcgcaa ggaaacacca atcaggataa tacctggaac aaaaaagagt gattgctttt
    14821 tcatataata cctcttctag ctgattttaa taacagctta ttttaaggct ttttcactat
    14881 aatgtcaagt aaggtttctg gctttcaaga taaaaatggg aaagtctgga aaattatgat
    14941 agaatggtgg aaggaaaaat tcaggagagt agtagtgact caaaatgttg aaagtcttct
    15001 cgtatccatt gtaatcagtg catacaatga agaaaaatat ctgcctggtc taattgaaga
    15061 cttaaaaaat caaacttatc ctaaagagaa tattgaaatt ctatttataa atgctatgtc
    15121 cacagatggg accacagcta ttattcagca atttataaag gaagatacag agtttaactc
    15181 aattagattg tataacaatc ctaagaaaaa tcaagctagt ggttttaacc tgggagttaa
    15241 acattctgta ggggacctta ttttaaaaat tgatgctcat tcaaaagtta ctgagagttt
    15301 tgtaatgaac aatgtggcta ttattcaaca aggtgaattt gtctgtgggg ggcctagacc
    15361 gacgattgtc gaaggaaaag gaaaatgggc agagaccttg catcttgttg aggaaaatat
    15421 gtttggcagt agtattgcca attatcgaaa tagttccgag gatagatatg tttcttctat
    15481 ttttcatggg atgtataaac gagaggtttt ccagaaggtt ggtttagtaa atgagcaact
    15541 tggccgaact gaagataatg atattcatta tagaattcga gaacatggtt ataaaatccg
    15601 ctatagccca agtattctat cttatcagta tattcgacca acattcaaga aaatgctgca
    15661 tcaaaagtat ttaaatggtt tgtggattgg cttgacaagt catgttcagt ttaagtgttt
    15721 atcattattt cactatgttc cttgtttatt tgttttgagt cttgtgttta gtctagcatt
    15781 gttaccgatc acattcgtat tcataacttt actattaggt gcctattttc tacttttgtc
    15841 actactcact ttgctgactt tattaaaaca taaaaatgga tttctaattg tgatgccctt
    15901 tcttttattt tccattcact ttgcttatgg ctttgggacg attgtaggtt taattagagg
    15961 atttaaatgg aagaaggagt acaagagaac aataatttat ttggataaaa taagccaaat
    16021 aaataaaaat atgctataat aacaatatag taaaactctt ttaaggagga gtagatttct
    16081 atgaataaaa aactaacaga ttatgtgatt gatctggtgg aaattttaaa taaacaacaa
    16141 aagcaggttt tctggggaat atttgatatt ttcagtatgg tggtttccat cattgtatct
    16201 tatattttat tttatgggct gattaatcca gcacctgttg actacattat ctatacgagt
    16261 ttggccttcc tgttctatca attgatgatt ggtttttggg ggttgaacgc gagcattagt
    16321 cgttacagca agattacgga tttcatgaaa atcttttttg gtgtgactgc tagcagtgtc
    16381 ttgtcatata gtatctgtta tgccttcttg ccactcttct ccatccgttt catcattctc
    16441 tttatcttgt tgagtacctt cttgatttta ttgccacgga ttacttggca gttaatctac
    16501 tccagacgca aaaaaggtag tggtgatgga gaacaccgtc ggaccttctt gattggtgcc
    16561 ggtgatggtg gggctctttt tatggatagt taccaacatc caaccagtga attagaactg
    16621 gtcggtattt tggataagga ttctaagaaa aagggtcaaa aacttggtgg tattcctgtt
    16681 ttgggctctt atgacaatct gcctgaatta gccaaacgcc atcaaatcga gcgtgtcatc
    16741 gttgcgattc cgtcgctgga tccgtcagaa tatgagcgta tcttgcagat gtgtaataag
    16801 ctgggtgtca aatgttacaa gatgcctaag gttgaaactg ttgttcaggg ccttcaccaa
    16861 gcaggtactg gcttccaaaa aattgatatt acggaccttt tgggtcgtca ggaaatccgt
    16921 cttgacgaat cgcgtctggg tgcagaactg acaggtaaga ccatcttagt cacaggagct
    16981 ggaggttcaa tcggttctga aatctgtcgt caagttagtc gcttcaatcc tgaacgcatt
    17041 gtcttgctcg gtcatgggga aaactcaatc taccttgttt atcatgaatt gattcgtaag
    17101 ttccaagaga ttgattatgt acctgtgatt gcggacattc aagactatga tcgtttgttg
    17161 caagtctttg agcagtacaa acctgctatt gtttatcatg cggcagccca caagcatgtt
    17221 cctatgatgg agcgcaatcc aaaagaagcc ttcaaaaaca atatccgtgg aacttacaat
    17281 gttgctaagg ctgttgatga agctaaagtg tctaagatgg ttatgatttc gacagataag
    17341 gcagtcaatc caccaaatgt tatgggagca accaagcgcg tggcggagtt gattgttact
    17401 ggctttaacc aacgtagcca atcaacctac tgtgcagttc gttttgggaa tgttcttggt
    17461 agccgtggta gtgtcattcc agtctttgaa cgtcagattg ctgaaggtgg gcctgtaacg
    17521 gtgacagact tccgcatgac ccgttacttt atgaccattc cagaagctag ccgtctggtt
    17581 atccatgctg gtgcttatgc caaagatggg gaagtcttta tccttgatat gggcaaacca
    17641 gtcaagattt atgacttggc caagaagatg gtgcttctaa gtggccacac tgaaagtgaa
    17701 attccaatcg ttgaagttgg aatccgccca ggtgaaaaac tctacgaaga actcttggta
    17761 tcaaccgaac tcgttgataa tcaagttatg gataagattt tcgttggtaa ggttaatgtc
    17821 atgcctttag aatccatcaa tcaaaagatt ggagagttcc gcactctcag tggagatgag
    17881 ttgaagcaag ctattatcgc ctttgctaat caaacaaccc acattgaata aaaaagaaaa
    17941 acgcatagta tcaagttaca caaccttggt aatatgcgtt ttattatgta gagacttata
    18001 ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg ccgtatgtat atgttactga
    18061 cttcgtcagt tctatccaca acctcaaaac agtgttttga gctgacttcg tcagttccat
    18121 ctacaacctt aaaacagtgt tttgagcagc ccgcagctag tttcctagtt tgctctttga
    18181 ttttcattga gtattacttc attttcttct gaaatagagt tgtcgcccag tctatgctat
    18241 tgaaaatacg ccaaaacttc taagggtttg tgagcgatat aatcaggttg atagtttagt
    18301 agatctgctt gctctccaaa tccccaagtg acggccaatt tctgaatacc tgtttctcga
    18361 gctcccagca tatcaaactt ggtatctccg atgatgatgg cttgttctgg tgctagttga
    18421 tgtgtctgta aggcttggtg aatgacatct gccttatggg gtgcttcagg gctagaacca
    18481 taaataccat caaagaaatg atggatttcc aagtttttgg ccatgtcttg agcagtagat
    18541 gtattctttg tcgtggtgat gtagagtgga taactgctcg ataactcctc aagcaagtct
    18601 ataatctgag gaaagagttg agcttcatag atgccttttg ccttatagta agaacgatat
    18661 atctgcatgg cttcagaaat ttggtctttg gacaggcagg tcgcaaaact actttcgaga
    18721 ggtggtccca taaaaccacg aatagttttg gcatcagggc taggcacccc cagctcttta
    18781 aaggtatagg taaaggcatt gtgaatcccg atagaactat caacgagggt tccatccaaa
    18841 tcgaaaaaaa tcgctgtgat agaggtcatg gtttctccta tttgataagc ttattctccg
    18901 aaaatctctt tttggaggcg acgaccagta ggggtggtag cgagtccacc ttcagctgtt
    18961 tcacgaaagg cagttggcat gcttgctcct acttggtaca tggcatcgat cacttcatcc
    19021 acagggattt tagattcgat acctgccaag gccatgtctg ctgcgatgaa agcaaagcta
    19081 gctcccatgg cattacgttt gacacaggga acttcgacca aacctgcaac agggtcacag
    19141 atgaggccta gcatattttt aatgacaaag gcaatagctt gactggcctg ataaggtgtt
    19201 ccacctgcag ccagagtcaa ggcggcagca ctcatagcag aggctgaacc aacttcagct
    19261 tgacatccac cctcagcacc tgagatggag gcattgtttg cgatgactag tccaaaggca
    19321 ccagcagcaa agaggaaatc caattgttgc tcgtggctga ggtctaattt ttcaatagca
    19381 gcagtgagaa cggaagggag acaaccggca cttcctgcgg taggagtagc gcagaccaag
    19441 cccattttag cattgtgttc attgactgcg atagcatttc gggcagcaga gagaatcgtg
    19501 taatctgata aagttttttc gtttttgatg tagtgatcca atttggcagc atctccacct
    19561 gtcaggccac tacgagattt attttcattg aggccaagtt ggacagaggc tttcataact
    19621 tccagattgc gttccatgag aaggaagact tcttcacgtt cgcgaccggt caattcaaac
    19681 tctgttgtaa tcatgagttc tgcgacattt ccttgaaagt ccagatctgc ttgctcgacc
    19741 aattctttga tagaataaaa catgcttcct cctatttaaa gaaattgaca ttgtggagat
    19801 gagggatttt tcgaatttct tcgatagcct catcacagtt gcgactgtca acttcgataa
    19861 tcataatggc tttttcacca gctttttcac gagtgacatt catctgggcg atattgatac
    19921 catagcggga aagcgcctct gtaacaaggg caatcatacc tggaatatct tgatgaacga
    19981 tgatgatagt cggtgtattc atattgagag agacggcaaa accattgagt tcggttacct
    20041 gaatatttcc tccaccgata gaaataccag tcacgctgat ggtcttgtgg gcatttttaa
    20101 cagtaatttt agtggtgtta gggtgagggg cattgctgtc tttctgaatg gtccagacaa
    20161 tcttgatacc acgcttgtgg gcaatttcca gactatttgg aatttcagga tcatctgtat
    20221 ccattcctaa aatacctgca acaagggcta ggtctgttcc gtgaccacga taggtcttgg
    20281 caaatgagtt aaaaagttgg aattcaactt ctgtcggagt atcatcaaaa atggaagaga
    20341 caatcttccc aatacgaaca gcaccagcgg tatggctact agatgggcca atcataactg
    20401 gtccgatgat atcaaagaca gattgaaaac gaagtgattt catcagtttc cccttataaa
    20461 aattcttatc tctattatat caaagaatga ggggcttggc tttaattgtg gatgaaaacc
    20521 tttctaatac ctcaaatagc ataaaaatag tatcttttat gacaaaaaac accttattta
    20581 gggaaataaa aaataatttt gtaatatttc tacataaaag tgtcaagaaa cggtaatatt
    20641 taaagggtat gatagaacta tagaaagaag gagaattttc gaatatgaaa tcaataacta
    20701 aaaagattaa agcaactctt gcaggagtag ctgccttgtt tgcagtattt gctccatcat
    20761 ttgtatctgc tcaagaatca tcaacttaca ctgttaaaga aggtgataca ctttcagaaa
    20821 tcgctgaaac tcacaacaca acagttgaaa aattggcaga aaacaaccac attgataaca
    20881 ttcatttgat ttatgttgat caagagttgg ttatcgatgg ccctgtagcg cctgttgcaa
    20941 caccagcgcc agctacttat gcggcaccag ccgctcaaga tgaaactgtt tcagctccag
    21001 tagtaagtga aacagttgtt tcaactgtaa gcggatctga agcagaagcc aaagaatgga
    21061 tcgctcaaaa agaatcaggt ggtagctata cagctacaaa tggacgttat atcggacgtt
    21121 accaattaac agattcatac ctgaacggtg actactcagc tgaaaaccaa gaacgtgtag
    21181 cagatgccta cgttgcagga cgttacggtt catggactgc tgctaaaaac ttctggctta
    21241 acaatggctg gtattaagaa ctaacgaaca aataatatgt aaaaggtcga ggagctccct
    21301 cgactttttt tataatttct ttggttgata atgggtctct acttcttttt tgagatgaga
    21361 cagcatagaa gtttcctcgg tcagctccag aagtgagaaa cctttttgga taagtttagc
    21421 attatctgta caaatcccaa tacggacata gcagatagca agcctatcgt agcttttctt
    21481 attcttggcg tcctccagta aagtgtagca gatttgctta cacatgtttt tatcttgatt
    21541 gtatagatag agtgtggaaa ggtttagcag gattgctatt cgcaagtcat ataaatgttg
    21601 atagttttta tagacttcta agcgttgcaa gattttctcg gattattgac aaataaacgg
    21661 acattctgat agacgattgc cctagcggct tagtgtaaac tttacaaatt tggcttgtaa
    21721 tttttttata aaattcactt cagttacttg acagttatta tattttcgct tattatatag
    21781 ataaaaggat gggataggat tttaaaaatt tgaaagcgct atccatattg tttattggac
    21841 tgattcttga gtaatagtta gagtgtgctt aatactactc tggttgttca aggacctgat
    21901 acagaagcgc accattctcc cggttaagag taagttcgtt gttaaaaaat gaaatgagat
    21961 agaaggaagg tgagtccaat ggactacgat acttgttgat aaattactat agctgttttt
    22021 acggaacagc tctcgataat aggagaaata aatcatgaga aaattagtta aaattggtgt
    22081 tgcatcttta atggtatgtg gtatacttgc tactacaaat gctttagcag tatgggttga
    22141 gggtggtcaa tggaactatg gagtaggttg gacaggaact tttggatatt ctgattactt
    22201 acattctact cgatatcata cagcaactgt tagacatggg ggtagaacct ctaaggatta
    22261 tgcaaaacct gaggcatggg ctagagcttc cctcaccaag attccgccaa caggaatgga
    22321 atatttctat ggatttgagt aaaattcttc cctctcctat ttggagaggg aaaactgtag
    22381 tggaggcact tttatgaaaa aaatcagtaa tttctgtatg ttactcctgc ttctgtgtac
    22441 cacttttttt gtttttaatg taaactatac acgagaagtg gttcggattc aagaaatggg
    22501 aaagactgta gattctttgg atttgtattt gaaagatatt aacgaacctg cagcgtctgt
    22561 tcttcgattt tttgaggatg tatcaaagga gtataaagtc tccatcatca aaacagacag
    22621 tggtgatgag gtggtcaagt ctggtgtttt tgataaagat accttcccct accaagagtt
    22681 tgggatttct tctcttgatt ttaccacaga tggtgaagga gtctatagta ataaagaaat
    22741 ttccaataaa cttggtacga ttccgacctt tctaaaagcc aaacctattc agcttatgac
    22801 ttttcaaacc tatatcaagg atacatctcg tagtttaaat ggtcgctata cgataacttc
    22861 tacacaagag atggacaagg ataggattgt acagaaatgg agcgattttt tcaagataga
    22921 ccaggctacc ttgctagagc cgacctacaa aagtgcagtg gaagtcataa atcgagattt
    22981 gcttttatct gccattgttt ttgtcttggc tattttgctt cttgtgttag tgacagtgta
    23041 tcaaccgatg atggagatga aaagagttgg ggtacaaaaa ttacttggtt ttcaagatag
    23101 ggctgtttta gctgatgttg taaaaggcaa cctttacctc ctcctaggtg gggctcttgt
    23161 gatcaatcta ggcgtgtttt tcttgcttga ttataagcca aaagatttgt ttcctatgct
    23221 gtggttgtct cattttttgc tgttgcagct ttatctcttt atcagttggt tgacttacct
    23281 cttaatccaa aaaatgacaa tcagctctct gctgaaaggt ttttcatctt tcaaatttgg
    23341 tcttatcttc aattatgtga tgaaaatagg gacaactatt ttactgacgg ccttactgat
    23401 tggggtgggc agaagtttag aacaagaaaa caaagaactt gcttatcagc aacagtgggt
    23461 aagtcaaggt aattacctga ccttagaaac cttcaaactc aatgataatc tgtggcaaga
    23521 agagctagca gggtcaggga aatctacaga ttatttctat cgattttatc aggatttggt
    23581 agaaaaaacg caggcgggct atgtgcagag tagcagtctt cctgtaaaaa attttgtcca
    23641 atcagaacag attcagcaat atcagttaac agatacggtg gatgtttact atgccaatcg
    23701 caattttcta aagagcaagg gattcaagct accagatacc ggtattaaaa aagttatttt
    23761 gatgccagca agtacgaaag gtgaagaaga taaaaatcag ctcttgggga agttaattgc
    23821 ctttcattcg atgaagtatg aagagcagca aaaacgaacg atagaggaga tggatgtcga
    23881 gattgcctat tatgaaggag attggtcatt tttcccatat agtgataagc gaaaggaaaa
    23941 tctctccaat ccaattatta gcttggtcaa tgattctgat atgatgtggg atgagaaagc
    24001 ctccctgtca acaactggct taaataatcc gattaaaatt gaaaatacgg ttcaacatca
    24061 aaaagagatt acagagttag ttgagaaatt gtcagatgga aattatttaa aattttcatc
    24121 tattcaagcc attcaacaag agaaagtgga ttcttatcga gatgctgttc ggaattttaa
    24181 cctactcttt gctttgtttg gtctccttag catgatgatt tcctacttct tactagtaac
    24241 aactttctta ttgaagcgca gggatatcat taccaagaag tttatggggt ggaaactggt
    24301 cgatcgctac cgtcctctcc tcgttctgct cttgctgggc tatagtttcc ctcttctagt
    24361 cttgattttc tttgcccatg cgttcttacc acttctactg tttgcaggtt ttacatgtct
    24421 ggatatacta tttgtgctag gcttagcttc taggatggag aaaagaagtc tagtagagtt
    24481 attgaaaggg ggcatcttat gattgagttg aaaaatatta ccaaaaccat tgggggaaaa
    24541 gtgattttgg ataacttatc tctcaggatt gatcaggggg atttggtagc tattgttggt
    24601 aagagtggta gtgggaagtc gaccttgtta aatttattgg gtttgataga tggtgattat
    24661 agcggacggt atgagatttt tggtcagaca aatctagcgg ttaattctgc taagtcgcaa
    24721 acaataatcc gtgaacatat ctcttatctg tttcaaaatt ttgccctgat tgatgatgaa
    24781 acggtcgagt acaatctcat gctggcgctg aaatatgtga aattgcctaa gaaagacaag
    24841 ctcaaaaagg tggaagagat tttagagaga gtaggtttgt cagctacttt gcatcaaagg
    24901 gtctccgagt tgtctggggg cgaacaacaa cgaattgcag ttgctagagc catcttaaaa
    24961 cccagccagc tgattttagc cgatgaacct acaggttcgc tggatcctga aaatagagat
    25021 ttggtcttga agtttctctt agagatgaat cgagagggga aaacagtcat tatcgtgacc
    25081 cacgatgctt atgtagccca acaatgtcat cgaatcattg aattaggcga gggaaaatga
    25141 gttcgttcag cttcatttga ccgactgaat actcatattt ttcagagaga aatagcataa
    25201 ataggcctag gaatgatatt tttatgtcat tttcctgggt ttttctgttt taaattgaaa
    25261 aaaaatacaa tttaggcttg acaaaggatg agtataggag tattatttat acaataaaaa
    25321 agaataaaca taaaggaggc tttgttatga ataagatgaa gaaggtgttg atgacgatgt
    25381 ttggtttagt gatgctcccc ctactatttg cttgtagtaa caatcaatcg gctggaattg
    25441 aagccatcaa gtccaaagga aaattggttg tagccctcaa tccagatttt gctccatttg
    25501 aatatcaaaa agtggttgat gggaaaaatc agattgtggg ttcagatatc gaattagcca
    25561 aggctatcgc aacagaacta ggtgtcgaat tggaactatc tcctatgagt tttgacaatg
    25621 tactggctag cgttcaatca ggaaaagctg accttgccat atcaggtgtt tctaagacag
    25681 atgaacggag caaggtgttt gatttttcaa ctccctacta tactgcaaaa aataaactca
    25741 ttgtcaaaaa atctgattta gccacttatc agtctgtcaa cgatttggcg cagaaaaagg
    25801 tcggagcgca gaaaggttcg attcaagaga cgatggcgaa agatttgcta caaaattctt
    25861 ccctcgtatc tctgcctaaa aatgggaatt taatcacaga tttaaaatca gggcaagtgg
    25921 atgccgttat ttttgaagaa cccgttgcca agggatttgt ggaaaataat cctgatttag
    25981 caatcgcaga cctcaatttt gaaaaagagc aagatgattc ctatgcggta gccatgaaaa
    26041 aagatagcaa ggaattgaaa gaggcagtcg ataaaaccat tcaaaagttg aaggagtctg
    26101 gggaattaga caaactcatt gaggatgcct ttaaagcgtc cattgaaaaa tagaaagaag
    26161 gaaaagaaca tgagtaaaga aaaagtaatt ttggcctatt ctggcggttt agacacatca
    26221 gttgctatta cctggctgaa gaaagactat gatgttgttg cagtttgtat ggatgtgggt
    26281 gaagggaaag acttagattt catccatgat aaggctctta aggttggggc agtcgaatct
    26341 tatgtcattg atgttaagga cgaatttgct acagattatg tgctagtagc tctccagtca
    26401 catgcctact atgaacaaaa gtaccccttg gtatctgcct tgagccgccc tcttatttct
    26461 aaaaaattgg ttgaaatagc gcatcagaca ggagcgacta caattgctca tggttgtaca
    26521 ggtaagggga atgaccaagt acgttttgaa gtatcgattg cagccttgga tctcaattta
    26581 aaagtgattg ctccagttcg tgaatggaaa tggtctcggg aggaagaaat ttattatgcc
    26641 aaggaaaatg gggtgcctgt tcctgctgac cttgacaatc cctactctgt cgaccaaaat
    26701 ctttggggac gtgccaatga gtgtggtatt ttggaaaatc catggaatca ggctccagaa
    26761 gaagcctttg gcatcacaac ttctccagag caagctccag atatgccaga atacattgag
    26821 attgagttta gtgaaggtgt tccagtttcc ctcaatggag aagtgttaaa attggcagat
    26881 ttgattcaaa aactcaatga aatagctgga aaacatgggg ttggacggat tgaccacgtg
    26941 gaaaatcgct tggttgggat taaatcaaga gaaatctatg agtgtccagg tgcagtgacc
    27001 ctgctgacag ctcataagga aattgaggac ttgacgcttg tgagagaagt ggctcatttt
    27061 aaaccaatca tagaaaatga attatcaaat ctcatttata atgctttgtg gtttagttcg
    27121 gctacacaag ccttgattgc ttatattaaa gagactcaaa aagttgtcaa tgggactgca
    27181 aaagtcaaac tgtataaggg gagcgctcag gtcgtggctc ggaaatcacc aaattctctt
    27241 tacgatgaaa atttggcgac gtatactagt gcagataccg ttgaccaaga tgcggctgtt
    27301 ggctttatta agttatgggg acttccaacc aaggttcatt ctgaggttca aaaaagcgcc
    27361 aaataggacg attggataga gaggtggatg tgatatggct aagaatacaa aattatgggg
    27421 tggtcgcttt ggcaggaacg actttcccca ttgatcgcca attgtctagc gatttgctgg
    27481 agtttaagca accttataca aattctttgg atgctgttag tgaccgcgat tttatcttag
    27541 aatttctatc aaatgccagc atactcatga tgcatatgag tcgtttttgc gaagaaatga
    27601 tcaattggtg tagttttgag taccaattca ttaccttgtc agatacgttt acaacaggtt
    27661 cctctattat gccccaaaag aaaaatccag atatggctga gttgattcga ggaaagactg
    27721 gcagagttta tgggcatttg tttggactgt tgacagtcat gaagtccttg cctttagctt
    27781 ataataagga tttgcaagaa gataaggaag gaatgtttga tacggtcgaa acgattttaa
    27841 attccctcga tgtgttggca ggtatgttat ctagtttgca ggtaaacaag gaaaaaatgc
    27901 aagaatcaac agagaaggac ttttcaaatg caactgagtt ggcagattat ttggcaggga
    27961 aaggcttgcc atttagagaa gctcatgagg ttgtgggaag attagtgcta gactctatca
    28021 agtctgctaa aaatcttcaa gattggactt tggaggaatt acaaacctat cattctctca
    28081 ttaccgagga tatctatgtc tacttgcaac ctaaaactgc tgttcaaaga cgaaattcct
    28141 tgggaggcac agggtttgac caagtcgaat accagattgc agtcgctaag aaagcgaatg
    28201 aagctaaaaa gtgatggagt gatgggttca gaataagagg ttggtcgatt ggcagcctct
    28261 ttcttgtcgt tgaaaaagtg agatatattg acttttgaaa aaaatgtcat aattgagttg
    28321 ggataaacgt aaaagtcata ctttctcgtt aaatcgttcg gcgattcatg gtgacatgga
    28381 cacatagtag taaacacact atgtggcttg gcagagctaa aaacttctgg cttaacaatg
    28441 gctggtatta agaactaacg aacaaataat atgtaaagag tcgaggaaat ccctcggctt
    28501 ttttatcttt ccttcgcttg gtaatagatc tctacttctt ttttgagatg agacagtata
    28561 gaagtttcct cggttagctc cagaagggag aacccttttt ggataagttt cgcatcatcc
    28621 ctacaaatcc caatacggac atagcagata gccagcctat cgtagctttt cttattcttg
    28681 gcgtcctcca gtaaagtgta gcagatttgc ttacacatgt ttttatcttg attgtataga
    28741 tagagtgtgg aaaggtttaa tagaattgtc attcgcaagt catataaatg ttgatagttt
    28801 ttatagactt ctaggcgttg caatattttt ccagtgatga gatggaggta ttcaatggga
    28861 aaactgaaaa gaatggtatt gaggattttt agatcactct cataccatgt atcttgtttt
    28921 tcaatttttt tccaaagttt tttgacaacc tgttctgcgt gttttgatag ttcccctgcc
    28981 ccgtgttgac ggagataaat aacaacttca agcatatctc tgatttcttc tatagggaga
    29041 tcgtggtggg tcttgaggta gtcttggcat ttttgaaata aattgacaag atcgctggtc
    29101 ccgataatgg aacgcatatt gagataggtt tgcataatct ctgtgcgttg acttggttga
    29161 taaagttgac agatatattc aaactcttca aaactcatat tgatttgacg gagaagaaat
    29221 tccatatttt catattttgg ggttgtcttg ccactttcga tttttgataa gctggttctt
    29281 gagagaacac ccccacagac ctcttcttgg gtcagcccct ttgactcacg tatttcttta
    29341 tagacctttc cgaaatcata acgcatgatt ttctcctttt cgtgaaaaaa gttaacaaac
    29401 aataaaattt tgttaaaaat attgtatcat agcaatgtaa aaagtaaaaa agaaagtcga
    29461 aataaatttg tgaaaaaagt taacgtaatt ttaaaatgag cttaataaga ggtactatgt
    29521 aggtagaaaa taaagatagg agaaaaagta tgaataaaaa aatattttgt attctagtat
    29581 gtattatatc attgattagt ctggctataa tctttccatg gggctggccg atataatgta
    29641 agggagtttg agttgttaaa ggaggctcag tccttgggca aaaatctgct gtactacaat
    29701 gcttggaaag atatcaagaa caaagaatga tacggttgaa aataaattaa ttcaagaact
    29761 actgggcagt gattgaggtt tgggtgacat caaagaaaag ttagatgaat tctaaagaat
    29821 tgagtatttc tatgttaaaa aaatatcctt gtacgatgca acatgaccag tcagattgtg
    29881 ctgcggcagt tgtttcaaca gttcttttat cttacaaaaa ggaactatca atcatgaaga
    29941 ttagggaaat tattggtaca gacatgtatg gaacgactgt cagtggtatt gtttcaggtc
    30001 tgaataagtt gaattttaca gtaaaagctg ttcgagtagc actggaagat ttgactccaa
    30061 aattaacatt tcctgcgatt cttcaagtta agaatgattt aggtcaaaat cattttgtgg
    30121 tattacatag tatcaaaagg aatagtaaat tttacgtagc agaccctgct agtggcatac
    30181 gcaagatgtc aagtgatgaa ctgggagaaa tttatcaagg tattactctt tttatggttc
    30241 caaattcgga ttttgaaaga gggaaactaa agggaaaagg acttcttgat ttatttggaa
    30301 ggttaatttt taatcaaaaa ggattgatta gtacagtcat attagcttcc tttgttttaa
    30361 gtatcattgg tattttatcg agtctctttt caaaagttat catggacgag gtgattccat
    30421 atgctttaaa aaatagtctg tatatgtttt tgatagtatt tggaatagtg tcgttcttac
    30481 agactcttct atctgcattt cgtcagcacg ttcttttgtt tctatctcga aaaattgata
    30541 taccggtttt aatgggatat tatgaccata ttattcatct tccttatagt ttttttggaa
    30601 gtcgtagagt tggtgatgtt ttaacaagat ttcaagatgc gatgacgata aagaatgtgt
    30661 ttacgtcagt ctctatttca ttagtcatgg atatcatctt gtcagttatt agtgcggttg
    30721 tcctttggac tattaatcaa tctttatttc tgatattagt ttttatggtt attgttaaca
    30781 tcattcttat atactgtttt aaaaagcctt ataaaaaaat taatcatgaa caaatggaag
    30841 caaatggact tcttaattca cagttaattg aatctattcg taacattgat accattaagt
    30901 ctcagcatga tgaggaacaa cgtttaaaca aaattgaaga aaaatttgtt catactttag
    30961 aaattggtta taaagagggc gttttgcaga atattcaatc tacaatatct tcaatgacct
    31021 caaccatggg tgggttatta tttatgggag tgggcgcctt atttatcatt gatggaaaaa
    31081 tgactattgg ggacctcttg gtttttcaga cattaagtca atattttaca gaacctattc
    31141 agaatttagt tggcttgcag ttaacctttc aagaggtaca ggttgcggtt agtcggcttc
    31201 aagaattgat ggaagtagat cgtgaagaca ttgccttgga ttatagtatt agagacttca
    31261 ccttatgtga tgacattgaa tttaaagatg taacatttgc ctatggttca cgccctcctg
    31321 ttatcaagga ctttaatttg cgaattaaac aaggagaaaa aatagctttt gttggagaaa
    31381 gcggagcagg aaaaagtacg ctagttcgtt tgttattaag atttataaat ccgagtgagg
    31441 ggaaaattcg tataggagaa aatgacttat cagatcttga ctatggtaaa ctacgtaaga
    31501 aaatttccta cattcctcag accatagaac tctttacagg gacaattatt gataatctaa
    31561 aaattggtaa tccttctgtt acatatgagg atatggtgag agtttgtcgt attgttggta
    31621 ttcatgatac gattcaacgt cttcaaaatc gttatggctc ctttgtagaa gaaggcggtc
    31681 aaaatttctc gggtggagag aaacaacgat tggctattgc aagagcacta ctgagtaaag
    31741 ctgatttgta tatatttgat gaggcaacct ctaacttaga ttcatttagt gaacagatta
    31801 ttcaggattt aatctttaat aaaataatag ataagacaac aattgtagta gcccacaggc
    31861 tgtctacaat tcttcgatgt gataagatat gctttttaga aaatgggact attgtggaat
    31921 atgggactca tgaagaacta atggcgaaaa atggaaagta tgctagaatg gttggtttgc
    31981 agagcgttca agtgaatcaa caaattcagt cacaggctgt gttagatata gaggaggtta
    32041 cttatggcta agttagaggt aaaagataat aaaaaactgg tactaaagtc agttatctgt
    32101 aaaaagttac atgatacaaa agtagaagat gtagatcagg aaattaataa atttcatcaa
    32161 catttgcagt tgttaaaagc acaaattttt ggtccattaa ttgtaaaaag ttgtggtact
    32221 actattcatg atgatggatt aataacgact gattttgagt tttatattca agctcataat
    32281 gctcaacagt acagtaacat ttatgatgta caggattcta tctctgttcc atattgttta
    32341 tatgttcgtt ttgaagacag tccagagtat ctacagtatg cgtattctaa attggatcta
    32401 tatgtctatg aaaatgatat tcaaacggat gggattgtct atacagttta tgttaattct
    32461 tctcctgaaa aaatggtagt agatattttt agaccaattg taagcctatg aaattatata
    32521 ataaatcaga attacgttat tctcgtattt tctttgataa gagaccacca gcttttgcgt
    32581 ttattctcat tatttcaact gctattatct taagcggtgc attggttggc gcagcttata
    32641 tacccaaaaa ctatattgta aaagcgaatg gaaattcagt tataacaggt acagagttcc
    32701 tatcagcaat tggttcaggg aaggtagtta ctttacataa gtcagaagga gatatggtaa
    32761 atgctggaga tgtcattatt tcgttatcaa gtggacaaga aggtttacaa gcgagctctt
    32821 taaataaaca attggagaag ttacgtgcaa aagaagctat ctttcaaaaa tttgaacaat
    32881 cattaaatga gaaatacaat catttatcta attctggtga agaacaggaa tattatggga
    32941 aagttgaata ctatctgtct cagttaaact cggaaaatta taataatggt acccagtatt
    33001 caaagattca ggatgaatat acgaagttga ataaaataac agctgaaaga aatcagttag
    33061 atgccgactt gcaagctcta caaaatgaat tgcttcaact tcaacagcaa ggagactcac
    33121 cttctttatc agatacgaca tcagctgatg ataaagctaa gttagaaact aagatatcag
    33181 aaataacaac aaaaatcgaa gcattaaaaa caaatattac ttctaagaat agcgagattg
    33241 atagtcaaca aagcaatatt aaggatatga accgtaccta taataatcca acttctcagg
    33301 cttataatat ttatgctcaa ttaattagtg agttaggtac tgctcgttca aacaacaata
    33361 aaagtattac agagcttgag gctaatcttg gagtggcaac aggtcaagat aaagcacata
    33421 gtatattagc gccaaatgaa ggtactctgc attatctggt acctttgaaa caaggaatgt
    33481 ctattcagca ggggcaaacg atagcagaag tttcagggaa agaaaaaggt tactatgtag
    33541 aagcttttgt acttgcgagt gatatttctc gtgtttcgaa aggagcaaaa gctgatgttg
    33601 ctattactgg tgtaaatagt caaaaatatg gaacactaaa gggacaagtc agacagattg
    33661 attcaggaac aatttcccaa gaaacgaaag aggggaatat tagcctctat aaagtcatga
    33721 tagaattaga aaccttaact ctaaaacatg gaagtgagac agtcgtcctc caaaaggata
    33781 tgccagttga agtgcggatt gtctatgata aagaaaccta tcttgattgg attttagaaa
    33841 tgttaagttt caagcaataa ttggttttaa accccttagg taacctataa aaataaataa
    33901 ggtagagaaa ggatatctta tctaggtagc taagtgatag aaacacagtc gacgattact
    33961 tgttaggaaa ctatcctaac catgcttaat aaaaaaggag aaaataaatg gaactcatat
    34021 tgccaaataa ttatgttgat cttgaacaag aagagatgat gtatcttgat ggcggagaac
    34081 caatgtcaat ttcggccatt gttgccttgg ctatcacaat tggtggcgca tcgtatagca
    34141 caggatatgt gttaggagaa agagtctact attcaggata taaaaactct gattatcaaa
    34201 aaaataagtg gggtattagg ggagcaatgc tggctgcatt tggagcaata ggtgcagtag
    34261 ttatgctcgg ttttgaaaat agatactatg ctttggttac tggtagagga taaaatgtta
    34321 agagtaatag tagttattca atctttagta ataatactgc ttgctgttgc tttattatta
    34381 tctcggaaaa actttgattc gttaaatgtt gttcttataa tgatgatcgt atcacaattg
    34441 ttgttattag tatatttgat aaaattaggg aatcagtgat tagctgttat ttgaattaag
    34501 taaactgtta agcttcaagc agtaactggt tttaaatatt taaaataaga taaaggaagg
    34561 aagtctaatt taggtaacta aacaaagcct gcgatcactt gttaggaaac tatcctaacc
    34621 atgcttaata aaaaaggaga aaataaatgg aactcgtatt accaaataat tatgttgctc
    34681 ttgagcaaga agagatgatg tatcttgatg ggggagctta tttaagcaag cgtgcttgtc
    34741 aaggaatttg cgcagcttta gctatgagtc caggaacttt tatagcatta gctggagctg
    34801 cagttttaac caaaaaacta ataaactata ttaaagttgg aggccttgga ggttggctta
    34861 ttggtgcagc agcaggtgta ttggctgggg cggcaggaag aatagcttac tgtattggat
    34921 atggtgctct taatagaggt tgtgatatta gcgggaaccc ttatccttgg gatggattca
    34981 tatctgcgac agtaagatga gtaatgtaga taagattcga aaaatacaca ttatcgtatg
    35041 ttggatgtat atatttttat cattcagggc gattataaat gacacggagt attttttgct
    35101 tattttttta gcttttatct actcaatagt atcactacct ctatattctg tgaaaaataa
    35161 aatagtatct atctgtctag ccataaattc gattctgtta atgagtttcc ccattttaat
    35221 caataagttt ttcccagaaa gttttttgac ttataccgta ttaataagtg tttttattac
    35281 agagttgata atttttcatt taattgggaa agattttgat a
//
LOCUS       DBEJZV010000023        27959 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.23, whole genome shotgun sequence.
ACCESSION   DBEJZV010000023 DBEJZV010000000
VERSION     DBEJZV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27959
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.23"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..545)
                     /locus_tag="ACL3S0_001384"
                     /pseudo
     CDS             complement(1..545)
                     /locus_tag="ACL3S0_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(743..1147)
                     /locus_tag="ACL3S0_001385"
     CDS             complement(743..1147)
                     /locus_tag="ACL3S0_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGR1312284.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQLIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            complement(1144..1308)
                     /locus_tag="ACL3S0_001386"
     CDS             complement(1144..1308)
                     /locus_tag="ACL3S0_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312285.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(1605..1724)
                     /locus_tag="ACL3S0_001387"
     CDS             complement(1605..1724)
                     /locus_tag="ACL3S0_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR1312286.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            complement(1727..1957)
                     /gene="blpU"
                     /locus_tag="ACL3S0_001388"
     CDS             complement(1727..1957)
                     /gene="blpU"
                     /locus_tag="ACL3S0_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGR1312287.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(2026..2295)
                     /gene="blpJ"
                     /locus_tag="ACL3S0_001389"
     CDS             complement(2026..2295)
                     /gene="blpJ"
                     /locus_tag="ACL3S0_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HGR1312288.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(2762..2959)
                     /gene="blpI"
                     /locus_tag="ACL3S0_001390"
     CDS             complement(2762..2959)
                     /gene="blpI"
                     /locus_tag="ACL3S0_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HGR1312289.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            3241..3828
                     /locus_tag="ACL3S0_001391"
     CDS             3241..3828
                     /locus_tag="ACL3S0_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGR1312290.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLR"
     gene            3755..5398
                     /locus_tag="ACL3S0_001392"
     CDS             3755..5398
                     /locus_tag="ACL3S0_001392"
                     /inference="COORDINATES: protein motif:HMM:TIGR01193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HGR1312291.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            5409..6770
                     /locus_tag="ACL3S0_001393"
     CDS             5409..6770
                     /locus_tag="ACL3S0_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGR1312292.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGENRI
                     PTGTEIAQVFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            6827..6982
                     /gene="blpC"
                     /locus_tag="ACL3S0_001394"
     CDS             6827..6982
                     /gene="blpC"
                     /locus_tag="ACL3S0_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGR1312293.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGWWEELLHETILSKFKITKA
                     LELPIQL"
     gene            complement(7024..8364)
                     /locus_tag="ACL3S0_001395"
     CDS             complement(7024..8364)
                     /locus_tag="ACL3S0_001395"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR1312294.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKAFKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(8378..9115)
                     /locus_tag="ACL3S0_001396"
     CDS             complement(8378..9115)
                     /locus_tag="ACL3S0_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1312295.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(9120..9458)
                     /locus_tag="ACL3S0_001397"
     CDS             complement(9120..9458)
                     /locus_tag="ACL3S0_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR1312296.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            9735..10064
                     /locus_tag="ACL3S0_001398"
     CDS             9735..10064
                     /locus_tag="ACL3S0_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR1312297.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(10232..11281)
                     /locus_tag="ACL3S0_001399"
     CDS             complement(10232..11281)
                     /locus_tag="ACL3S0_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312298.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(11278..12009)
                     /locus_tag="ACL3S0_001400"
     CDS             complement(11278..12009)
                     /locus_tag="ACL3S0_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312299.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMLRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            12077..12487
                     /locus_tag="ACL3S0_001401"
     CDS             12077..12487
                     /locus_tag="ACL3S0_001401"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR1312300.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQIAETIKNA"
     gene            12497..12784
                     /locus_tag="ACL3S0_001402"
     CDS             12497..12784
                     /locus_tag="ACL3S0_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312301.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            12946..13185
                     /locus_tag="ACL3S0_001403"
     CDS             12946..13185
                     /locus_tag="ACL3S0_001403"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312302.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHGKPTLTWFEEIFEEYYSPFHN"
     gene            complement(13519..14655)
                     /gene="dnaJ"
                     /locus_tag="ACL3S0_001404"
     CDS             complement(13519..14655)
                     /gene="dnaJ"
                     /locus_tag="ACL3S0_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGR1312303.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRGKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(15057..15413)
                     /locus_tag="ACL3S0_001405"
     CDS             complement(15057..15413)
                     /locus_tag="ACL3S0_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGR1312304.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(15415..17238)
                     /gene="dnaK"
                     /locus_tag="ACL3S0_001406"
     CDS             complement(15415..17238)
                     /gene="dnaK"
                     /locus_tag="ACL3S0_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGR1312305.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAESDKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(17727..18251)
                     /gene="grpE"
                     /locus_tag="ACL3S0_001407"
     CDS             complement(17727..18251)
                     /gene="grpE"
                     /locus_tag="ACL3S0_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGR1312306.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(18278..19312)
                     /gene="hrcA"
                     /locus_tag="ACL3S0_001408"
     CDS             complement(18278..19312)
                     /gene="hrcA"
                     /locus_tag="ACL3S0_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGR1312307.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(19476..19985)
                     /locus_tag="ACL3S0_001409"
     CDS             complement(19476..19985)
                     /locus_tag="ACL3S0_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HGR1312308.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCIATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            20590..22923
                     /gene="hsdR"
                     /locus_tag="ACL3S0_001410"
     CDS             20590..22923
                     /gene="hsdR"
                     /locus_tag="ACL3S0_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGR1312309.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKEDSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            22936..24399
                     /locus_tag="ACL3S0_001411"
     CDS             22936..24399
                     /locus_tag="ACL3S0_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR1312310.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            24399..25964
                     /locus_tag="ACL3S0_001412"
     CDS             24399..25964
                     /locus_tag="ACL3S0_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR1312311.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLAEQQRIIEAIESALEKVDEYAESYNRLEQLDKKFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYGNIPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLEFSLLDNDY
                     YIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIFQLTPFESS
                     EIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFEEQELITQK
                     VEKLFEKVNQLWK"
     gene            complement(25912..27192)
                     /locus_tag="ACL3S0_001413"
     CDS             complement(25912..27192)
                     /locus_tag="ACL3S0_001413"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR1312312.1"
                     /translation="MRIKSIYWNFGQNKPEKSFRYIDTSSIDRKKNIINYKNLQYLSP
                     EQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLIASTAFIVLDTLLNETYLKY
                     YLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLSEQQRIVEAIESALEKVDEY
                     AESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEE
                     GKIKKKDLDISIVSQGDDNSYYGNKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPP
                     RSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSI
                     GKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNST
                     SISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(27644..27793)
                     /locus_tag="ACL3S0_001414"
     CDS             complement(27644..27793)
                     /locus_tag="ACL3S0_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGR1312313.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            27758..27877
                     /locus_tag="ACL3S0_001415"
     CDS             27758..27877
                     /locus_tag="ACL3S0_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGR1312314.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         8998 a         5513 c         4960 g         8488 t
ORIGIN      
        1 ccaagatttt accagcttgt ccgatatttc tgcgactcat tttgaacaac ttcatatcat
       61 gacaatagtt cacagcgata tccaaagaaa taattctccc ttgacttgtg acaatcgcct
      121 gagccttcat agcgtgaaat ttctttttac cagaatcatt cgctaattct ttttttaggg
      181 cgattgattt gtacttccgt cgcatcaatc attaccgtgt cctcagaact gagaggagtt
      241 cttgaaatcg taacaccact ttgaacaaga gttacttcaa cccaccggct ccgacggata
      301 aagttgcttt cgtggatacc aaaatcagcc gcaatttgtt cataagttcg atattctcgc
      361 acatattgaa gagtggccat aagaaggtct tctaggctta atttaggttt tcgtccacct
      421 tttgcgtgtt taagttgata agctgttttt aatacagcta acatctcttc aaaagtggta
      481 cgctgaacac caacaaggag cttaaatcgt gcatcagtta gttgtttact tgcttcataa
      541 ttcatagaac tatagtaaaa tgaaataaga acaggataaa tcgatcagga cagtcaaatc
      601 gatttctaac aatgttttag aagtagaggc gtactattct agtttcaata tactatacca
      661 tattttgttt cgcagggaat ctattataaa agggtaagta ttgcaaaaac acttaccctt
      721 ttcttttata cttcattaag ctctactttt tataatactt caagccccac atgagcagaa
      781 gcatgatgat taagcagaga acagcgccaa tataagcgat tagttgttga taagattctc
      841 ctgctgtgat acctctatac aaacaaataa tagacataaa acctgtcaag ccgataaaca
      901 taagttgatt ggttctagga ctaaccaaat catcatcttc aaactctctt atcctcattt
      961 ccctagtgag ataaacagta accaaaatag aagccaagtt aataactact aaaagaaatt
     1021 ggaaaactac ggaaaaattt aaaaactgac gagatagaaa tagataagta gaaacaagca
     1081 agggcaactg acctaagaac aatctcgcaa ggaagatgtt ccgtttttta gcaagaaaag
     1141 ttttcatttc ttttctcctt tctttttatt gatagcaaaa tagatcataa ctgcaatcac
     1201 ataggctatg gtataaaata gctgatacca agcactctcc ctaagcggat atagaaagat
     1261 ggacatgatt agatacagaa cgaaaataat cagtattttt ttcttcataa gatttcctcc
     1321 taaatgtgcg atttatctta gttgagcaag aacatttaca ctgctagtat agcacttatt
     1381 ttgaccttgg atcactcaaa tcataaatgg tcatcaaaac ctcttgaatt gtaaaaatta
     1441 aaaaagcaag catgaaaaac atactttcct ctttatattg tattgatacc aacttgtttg
     1501 cagacttttc atcctgctat cacatatcat tttgacaggc gaaacaaaat taaagaaact
     1561 cccctgtaaa ttaagctagc aaatacaggg gagaaattta ttttttaggg ggtactatct
     1621 gtatcctttt tgggaaattt tgaaaatatt tttctaatta aattatccat ataaggacca
     1681 aatataccaa ctactaaacc aataataaaa cttttaaaat ccataattac caccaacatg
     1741 ttgctgcata ggctacacct ccaagtatag ctccacccgc agcaccagtt gctgcacctt
     1801 gccatgttcc tgttttaatg cctagttgaa gacctcttgc tgctgctcct ccaacacctg
     1861 ctttggcaaa atctccccaa ttgcatccgc caccttcaac gcaagcaagc atttcagtat
     1921 ccataacaga aaattgtgac atcatttttg tatccatgac aaatactcct tttttaaaaa
     1981 actaaaataa atcagaatag aatcctcata attttactat aagtcttacc aacttagtcc
     2041 caatttatca ccaaccatac ctcctaagca tgttaatcca cccccaattg caccaatgtg
     2101 tgctccaaca aatgcaccag caagtccagc tactcctaaa gtggccaaac ctgctccagt
     2161 tccaccagtt ataattcccg tagtgactcc tgtaatcagt gcattttgac aatcagtgga
     2221 gctatacccc ccttcaactt tcgcaagcat ttcagtatcc ataacctcta actgtgacaa
     2281 catttttgta ttcatgatga atacctcctt tttattttca atttgttacc aaagtcttaa
     2341 attcaataaa caaatagatt ttttatagta tctttttgat tttcttaaaa aagtatacac
     2401 gtctactatc ttcttaaagg tagcagtacc tattttttag tctaagattt caataatctt
     2461 gagtatctaa aatatcttaa tttcgttatt ctccttgcaa taaaaagttt tactatacta
     2521 tttattaact tgcagaaagc aaaaaatatt agtaaataat agtttatagt taagtttttt
     2581 attcctacca atccatcaac taagtaaagc atcaacgatt acataaacga ttgataatat
     2641 aattaaaatt ttgctaacta tcttattctc atcattctta gataactttg atattttgta
     2701 agtaagtaaa taagacagta aattaatagc gataataata ctatatttaa gaatcataat
     2761 cttacaaaga ggacataatt cctgaaccta cacaaataag tgttgctgct cccccagtta
     2821 tcggaccagt cgcagcagct aatagtactg ctccaataca accaccgatt gcagatccta
     2881 aattgcctct tcctccacta actatttcga gttcttcatt atccataaca gaaaattgtt
     2941 ccatcatttt tgtattcatg acaaatactc cttttttctt tttttatttt tgtcttgttg
     3001 taactttgat aagtttagta tatcatcgtt ttttaaaatt tttcatccag atcttgaatt
     3061 gtcatcgaaa cgtcttgaat tagctttttt atttcaagcc acctctaaat gtttaaaaaa
     3121 aataatttct aatcactttt ttaccattca ggaagtttta atgactattc aagatttcat
     3181 aaaatatgaa cttagtttta tgacataata gacctatcca ctatatgaaa ggaattgcca
     3241 atgacttctt ataaacgtac atttgttcct caaatagatg cgagagactg tggtgtcgct
     3301 gccttagcct cgattgctaa attctatggt tcagattttt ctctagctca cttgagagaa
     3361 cttgcaaaga ccaataaaga agggacgact gctcttggca ttgtaaaagc cgctgatgaa
     3421 atgggctttg aaacaagacc tgttcaagca gataaaacgc tctttgacat gagtgatgtc
     3481 ccctatccat ttatcgttca cgttaacaaa gaaggaaaac tccaacatta ctatgttgtc
     3541 tatcaaacaa agaaagacta tctgattatt ggtgatcctg acccttctgt aaaaatcact
     3601 aaaatgtcaa aagaacgctt tttctatgaa tggactggag tagctatttt tctagctacc
     3661 aaacccagct atcaacccca taaagataaa aagaatggtc tactaagcaa gcttccttcc
     3721 tctgattttc aaacaaaaat ctctcattgc ttacattgtt ctctcaagct tattggtcac
     3781 tattatcaat ataggtggtt cttactatct ccaaggaatc ttagatgaat acatcccaaa
     3841 tcagatgaaa tcaactttag gaatcatctc agttggtctg gttatcacct atatcctcca
     3901 acaagtcatg agcttctcca gagattatct cctaaccgtt ctgagccaga gattaagcat
     3961 tgatgtgatt ttatcctata ttcgccatat ttttgaactt cccatgtctt tctttgcgac
     4021 acgtcgtaca ggagaaatca tttcacggtt cacagatgct aactctatta tagatgcctt
     4081 ggcttctacc attctttctc tttttctgga tgtttctatt ctgattcttg tagggggagt
     4141 cttgctggca caaaacccta atctcttcct cctttctctt ctttccattc ctatatacat
     4201 gttcatcatc ttttctttta tgaaaccttt cgaaaaaatg aaccatgatg tcatgcaaag
     4261 taattctatg gttagctctg ccattatcga agatatcaac gggattgaaa ctataaagtc
     4321 gctcacgagt gaagaaaatc gctatcaaaa tatagacagc gaatttgtag attatttgga
     4381 aaaatccttt aagctcagta aatattctat tttacaaacg agtttaaagc agggaacaaa
     4441 attagttctg aatatcctta tcctatggtt tggcgctcaa ttagtcatgt caagtaaaat
     4501 ttctatcggt cagctgatta cctttaacac acttttttct tactttacaa ctcctatgga
     4561 aaatattatc aacctccaaa ccaaactcca atctgcgaag gtcgctaata accgtttgaa
     4621 cgaagtctat ctagtcgaat ctgaatttca agttcaagaa aaccctgttc attcacattt
     4681 tttgatgggc gatattgaat ttgatgacct ttcttataag tatggttttg gacgagatac
     4741 cttaacagat attaatctca cgattaaaca aggagataag gttagcctag ttggagttag
     4801 tggttctggt aaaacaactt tagccaaaat gattgtcaat ttctttgaac cctacaaagg
     4861 gcatatttcc atcaatcatc aggatattaa aaacattgat aaaaaagtct tgcgccgtca
     4921 tattaattac ctaccccaac aagcctatat ctttaatggc tctattttgg aaaacttaac
     4981 cttgggcggt aatcatatga ttagtcaaga agatattcta aaagcttgtg aagtagctga
     5041 aatccgtcaa gacattgaaa gaatgcctat gggctatcaa actcagctct ctgatggagc
     5101 tggtctatca ggaggacaga agcaacgaat cgctctcgct cgtgctcttt taactaaatc
     5161 tcctgtttta atactagatg aagctactag cggtcttgat gtcttgactg agaaaaaagt
     5221 tatagataat cttatgtccc taactgataa aaccattctc tttgtagccc atcgtctcag
     5281 tatagccgaa cgaaccaacc gtgtcattgt tcttgaccag gggaaaatca ttgaagttgg
     5341 tagccaccaa gagttaatgc aggcgcaagg tttctaccat catctattca ataaataagg
     5401 agaatgtcat gaatcctaat ctttttagaa gcgtcgagtt ttatcagaga cgttaccata
     5461 actatgcgac agtgttaatt atacctcttt cattactatt tactttcatc ttgattttct
     5521 cccttgttgc cacaaaagaa attactgtca cttcccaagg agaaatcgcc cctacaagtg
     5581 tcatttcatc tattcagtca accagtgata atcctatcct tgctaatcat ttagtggcaa
     5641 atcaagtagt tgaaaaaggg gacttactca tcaaatactc tgaaacaatg gaagaaagtc
     5701 agaaaactgc cttagcaact caattacaaa gacttgagaa gcaaaaagaa ggacttggaa
     5761 ttttgaaaca aagcttagaa aaagcgactg atcttttttc tggcgaggat gaatttggct
     5821 accataatac ctttatgaat tttactaaac aatcccatga tattgaactg ggtatcacaa
     5881 agactaacac tgaggtttca aatcaagcta atcttgccaa tagcagttca tcagctattg
     5941 aacaagaaat tacaaaagtt caacaacaaa ttggagaata tcaagagctg agagatgcta
     6001 tcataaataa cagagcacgc ttaccaacta gcaatccaca ccagtcaatt ttgaatcgtt
     6061 atcttgtagc ctcacaagga caaacacaag gaacggcaga ggagccattt ttatctcaaa
     6121 ttaatcaaag tattgcaggt cttgaatcat ctatcgcaag cctcaaaatt cagcaagctg
     6181 gtatcggaag tgtagcaact tatgataata gtttagcaac caaaattgaa gtactccgca
     6241 ctcagttttt acaaacagcc tcacagcaac aactaaccgt ggagaaccaa ttaacagaat
     6301 taaaagtaca actagatcaa gcgacacagc gcttagaaaa caatacctta accgctccaa
     6361 gtaaaggtat cgttcatctg aacagcgaat ttgaaggtga aaatagaatt ccaactggta
     6421 cagaaattgc tcaagtattc cctatcatca cagatacaag agaagtacta atcacttact
     6481 acgtagcttc tgactatcta cctctactag ataaaggaca aactgtaaga ttaaaactgg
     6541 agaagattgg aaatcacggc attaccatca tcggccaact tcagacaatt gatcaaactc
     6601 ctaccagaac agagcaaggc aatctcttta aattaaccgc tcttgcaaaa ctatctaatg
     6661 aggatagtaa actcatccaa tatggcttac aaggtcgcgt cactagtgta actgcaaaga
     6721 aaacatattt tgattatttc aaagataaaa ttttaaccca ttctgattaa ttttcagata
     6781 acactctata actatttatt atcttatcaa aaaggagaat cataacatgg ataagaaaca
     6841 aaacctaact tcatttcaag aactaacaac taccgaactc aaccaaatta caggtggagg
     6901 atggtgggaa gaactcttac atgaaacaat tttaagtaaa tttaaaatca caaaagcact
     6961 tgaactacct attcagctat aaaaacaaga ccgagaaaca agtactctcg gtcttatttt
     7021 tcatcattct gtatgtatca cagtaagtac ctgacgaaag acttgatttt gacaggtggt
     7081 atttagactg gtattaggat ggctttccac aatcttcatg acggtataga gaccaactcc
     7141 tctctcctcc cctttagaac tggctccaaa ggagaagatt tcagaaatat cgatgccctc
     7201 ttctttgatg gagttttcga tgataaaggt ctcctgtgct ccatttttta aaaaggcgat
     7261 tgaaacatga ggttgactag cttccacact ggcttcaata gcattgtcac aaaggataga
     7321 cacaatggtt agaaaatcaa gtagactcat cccctcgacc tgaatctcct caggaacttc
     7381 gacattaaag acaatgttct tatctctggc ttttaaaaat ttccctgcta gaagactttt
     7441 gaaggcttta tcacgaatat ttaccaatct gcccaggtca tatttattgt tctgcaattt
     7501 ctgactggaa tcctttaaga cggagccata gacctctttt atctgctcca tatcctcctc
     7561 ttcaatgccc agacgtaagc tagtcaagag gttggtataa tcatggcgaa aactccgtac
     7621 ttccttgtaa agctcctcta tatgccgact atagcgttcc atatctctat agcgcagggc
     7681 ctgctcttgt tccaatctct catagagttt ttccttcaaa taggtatcca atttcttgat
     7741 aacccccata aaaaagagta ggtaaaagac taggatgaga tggcgaacag tctttgattg
     7801 aatactttgt tcatattcaa aaaaagacag actttccatg actagatagt agccacccat
     7861 tatccagtta atctgagtca gggacttttg aaaggcttta tcgagaatct cctttctcaa
     7921 gctagtaaaa tcgtagtcca accatttcaa aaaagctaga gaaatgaaga aattgaaaat
     7981 tattatacat aacccagtaa atgagtagcc atcatatact tgcccttgtc ccaaaaatgg
     8041 aagcacaaaa taggagactc ctctataaaa gagattcacc aatatcattg gaaagagacc
     8101 ataaaagaaa aggagttttt taggaagccc tctcaataat aagaaagata agcctatgcc
     8161 gtacaagggt tccataaaat aagataggta aacatttcct actatatagc taatcatcac
     8221 aaaaacaaag gccaacagta tcttaaaaag aaaggcctta aaaatcctct cgaaagtaag
     8281 atcaattcca tccaccttaa agaagatgac aatttctagt ccattagtaa caagtgtata
     8341 caacaatatc caagcaatgt tcataaattc tcctagctca gtgtaattta ttgatggcct
     8401 cagacacttc cctgacctta taacgggcga ttagacaact tccaccattg ggaaagaaaa
     8461 gcagtttttc tttcttatcc aaatgcacca catttgcagg attgatgaga aaagagcggt
     8521 ggcactgcaa gagacggggc tcctgcttga aaacctcctc taaactcgct gtaaattcca
     8581 gcctgtctgt cttggtatag agaataacac gatgggctct gggcgacgtt tcgagatagt
     8641 aaacctcttt aaaaggatac tgaaattggg caaattttga tttaaagtaa aagcaatctt
     8701 ccgccagact tttactatct tgactattgg catagaggag ggctgtctcg atccgagatt
     8761 caaactcctc tgctgacaag gccttatcaa tgtagtccaa agcagacact tggtagcgaa
     8821 aagacagggg cataaactcc gagtgagtcg tcacaaagac aatcagggca taaggatccc
     8881 gatcccgaat ctttctagcc acttccagtc ccttcatctc ttcatttcga atctcaatat
     8941 ccaaaaagaa tagctgatgg gcccccttct catgcacttc agccagcagt tggtccggct
     9001 tgccaaatac ctcaaaagag ctaggaatga tatgatgtgc tttcaaaagt ttctcaatcg
     9061 tcgtttcaat tctagtctgt tgggaaaaat catcctctaa aacaaatatt ctcatcttct
     9121 tactctccct ctttcaacca tttttgacga atttctctat agcgacgtct ggcatacttg
     9181 acagcgtatt gaccttcttc tccgagaaaa aggattcttt cttgaaaatc aatcgatttt
     9241 aatttatcaa gattaaccaa acaatttcga tgacatctca tcaaggtttc cccacattgg
     9301 ttctcaagat tacttaaatt ttgaagcata ttaaaactag ctttttctgt aacaatctgt
     9361 acggtatggg ctttagttgg atgtgtttgg atatagtaga tatcgtcgac gtttacttta
     9421 tagactgttt tctgcgtctg aataatcata tgtttcattg gattctcctc ctaagaaaag
     9481 aataacagaa aagttctagc ccaagcccac ccaatcctaa acagtctttg aaagctccta
     9541 aaaggattat ttttctacaa catcatgatg agcttacaac tattttatca taaaattcac
     9601 tcagcgcaat tcaagacatt tcaatgacaa ttaaagattt gaataaaaaa aaagaattaa
     9661 aagtgataaa ctaacagtat caaaacacag ttgccagaag taagactggc acccagatta
     9721 aaggaggcat tcccatgaca gatacagacc ccatcaaaag agctcatact ttgattactg
     9781 acttaaacaa agcctaccaa gcatgcaaac aggcaagtgc tgacgacgtc cgctttcagg
     9841 agcaattaaa ctctattctt ggttttctag ccaaggctga aacagtggat aatcgattct
     9901 tgattgaact agaaaaattt taccagactt ccagtcttct catgggactc agcgctcttg
     9961 atccagatgc tccaactcgc gccgcttggc gggcctatga ccgcttccac tttgaccaag
    10021 tcaagaccaa gttaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaagc
    10081 tgtacttgag tacggtaagg tgacgctgac gtggtttgaa gagattttcg aagagtataa
    10141 gtctctacgg accaaccatt atcctgtagt aacaaaaaag aagctgagac agactgaact
    10201 caacttcttt tttagtgtcg tatcagcaat gttagtcctg catctgacgt tttacctgat
    10261 aaggcaaata caagactagt aaaaccaaac cagctcctag taaggctaga agggccagtt
    10321 tttcttggaa ggtaatcaac ccaacaacta attccacaag taaaacaaaa ctggtcaatc
    10381 ctcgaactac ctcctgtaag cctttttcct tttgcccctt gtccagtgga aagagttggg
    10441 tcaaatactg gtagtcaaag gcatgataga gggccagcaa ctgaaagagc aagaggtagt
    10501 taaagagaac caccactgct gtcgcaatcc aagcttgctc gataaaaacc tgcgccagta
    10561 cggaaagtaa gagaagacga agactgagag caaagaggtc gccatttcgc agataagaac
    10621 gcagatagag attttgccaa atcttcccag gcaccttctg aacagccttt aagataaagt
    10681 ccagataggc acgacgcttg acactgtttg aaattccctt gacctgcgta aagagggcaa
    10741 agaaacgaag caagacttgc ttacgcttgc tttcttgaga aataagatag tcccagtcca
    10801 gtccagtttc agtgaaaaat ttgctggcct tttgacgaaa gtggaaatat tttcctaccc
    10861 ccaataaaag cacatagagc agaaaaactg gcaagccata acccattgct aaaaacaagg
    10921 gcgcaaataa cagcaagaaa agggtctgta caaagagcca aaagactagg gaaatgccag
    10981 tttgacgctt gagatggagc ttgatttcct cttctccaac taagagaaag agcttgtctg
    11041 gagcctccat ataggtggca attcctcccc aaagtaaaag taaaacagac gtaattccta
    11101 caaacaaaag aataggccaa tgattttcag gaaaatgttg taagagttga ctgtactggt
    11161 aggctagaaa gcccaacagg acaagcagga ataagacaaa gtggtcattg agcacatagc
    11221 gcagataacc aagacactcc ttacgaaagg cctgctttct ctttaaaaac aagtctttca
    11281 taggtcctcc tcttttgtca gagccaagta aatatcattc aaactagcct caggcatatc
    11341 aaaggcttcg cgtagttgca ggagattgcc tttggcacgc acctctccct tgtgaagaat
    11401 gacaaaggca tcacacatct tctccgccga atccagcacg tgggtactca tgagaataga
    11461 cttgcccttt tgcttctcca cttccaaaag ctgaatcaaa tcagaaatag ccagcggatc
    11521 aagaccaagg aaaggctcat ccacgatgaa aagacttgga tccaccacaa aagcacagat
    11581 aatcatgacc ttctgcttca tcccttttga aaaatgaaca gggaaccagt ctaatttctg
    11641 ttccagacgg agcatcttta acaagggctc tactcgttcg aaagccactt tttgctcaat
    11701 accataagcc atagcaaccg tttcgatatg ctctctgagg gtcaattcct catacagact
    11761 aggcgtctca ggaatgtagc caatctgctt gcggtagcta gtcgcatctc cttgcagagt
    11821 caggccattg atattgatgg agccactata aggtgccaac agaccgataa tctcattgat
    11881 cgtcgttgat ttcccagcac cattgagacc aatcaaaccg accaactgcc cactttcaac
    11941 agtaaaggac acatctttca aaacaggaac atgaacatag ccacctgtca ggtttttaat
    12001 ttctaacata ttttctccaa atctggtata atgtagctat attatatcaa aattcaatac
    12061 agcagaggta gattttatgt cagattgcat tttttgtaaa atcatcgcag gggaaattcc
    12121 tgcttcaaaa gtatatgaag atgagcaggt ccttgccttt cttgatatct ctcaagtaac
    12181 actaggacac accttggtcg tgccaaaaga acactatcgc aatcttttgg agatggatgc
    12241 tacgagcgcc agccaactct ttgcccaagt accaaaagta gctcaaaaag tcatgaaagt
    12301 cactaaggct gctggtatga atatcatttc caactgtgaa gaagtcgctg gtcaaacagt
    12361 ttttcatact cacgttcacc ttgtgcctcg ctacagtgct gacgatgacc tcaagattga
    12421 ttttatcgcc cacgaaccag actttgacaa acttgctcaa atcgctgaaa ccatcaaaaa
    12481 cgcttaagga gttgctatga aattatccaa cctactgcta tttgcaggag ctgcagccgg
    12541 aagttatctg gttacaaaaa atcgccaaac catcacagat gaagtcttga ataccactga
    12601 ccgcgttcaa gctatcaagg acgatgtgga tattatccaa aacagcctgc aaatcattaa
    12661 ccagcaaaaa gaacttatca aggaatacca agaagacttg acttacaagt ttaaggtctt
    12721 ggaaaaggat atccagacta gactagctgt gataaaagaa atgcagggaa ctgaagataa
    12781 gtaaaaagag ccccccggct cttttttaaa acgtaaacaa gttatagtga attgaattta
    12841 gaatagcaca ccatagtttc taaagcattg ttagagatta ctttaaaatc ctcttatcaa
    12901 tttgttcata ttctatttca atctattata tatatcccat caactatgca tcataattta
    12961 ggtaactcat actcaataaa aatcaaaaag caaactagaa agctaggcac agactgctca
    13021 aaacaccgtt ttaaggttgt ggatagaact gacgaagtca gctcaaaaca ctgttttgag
    13081 gttgtggata gaactgacga agtcagtaac catacccatg gcaagccgac gctgacgtgg
    13141 tttgaagaga ttttcgaaga gtattattca ccatttcaca actaaatcga agactttctg
    13201 ccgtaatgaa aacacctgaa acagcttggt ttcagctgtc cggaaacttt aaaacttagg
    13261 ttcaaagttt aggtatggaa cttcgaagga ggtcactacc gtccgtcatt acttaggaaa
    13321 gtcttaaaaa atctataaag taaaaagagc ccgacagctc tttttgttta tactcaatga
    13381 aaatcaaaaa gcaaactagg aaactagcca cgggctgctc aaaacactgt tttgaggttg
    13441 tagatacgac tgacgaagtc agtcacatat atacgacaag ccgacgctga cgtggtttga
    13501 agaaattttt gaagagtatt attctccatc aaaggcatct ttaatatggt caaagaagcc
    13561 ttttttcttt ggatttactt tcaagtcacc agcagccgcg aattctttca aggctacttt
    13621 ttggcggtcg ttcaagcctg tcggtgttac gacattaaca gtaacgtatt ggtcaccaac
    13681 tgcaccgcca cgaaggctcg gtgccccctt accacgtagg cggaatttct taccagtctg
    13741 agttccctct ggaataacca attcaacatc accgtgaaca gttggaatat ctactgtatc
    13801 accaagagcc gcttggacaa agttgaggtt gagattgtag aagatagtcg ttccttcacg
    13861 ttcaaacttg tcgctagctt ctacagaaac tactacatac aagtccccat aaggtccacc
    13921 gttaaagcct gcttcgcctt gaccagcgag gcgaatttgt tgacctgttt ccacaccagc
    13981 agggattttc acatgtacgc tatgagcttg tttctcatgg cctgttccat gacaggttgt
    14041 acatggatat ttgatttctt ttcctcgacc gtgacagaca tcacaggtta cttggcgacg
    14101 catcatacca agaggagtct gcgtatcgac gttaatgaca ccagcgccat gacagcgtcc
    14161 acaagtgact ggacttgtcc ctggcttagc accagagcca ttacatgtac gacagccagc
    14221 ttcacgatga tacttaactt ccttctcagt tccgaagata gcttcttcaa aggtcaaatt
    14281 gacacgatac tggagatcat ctccttggcg aggagcgttt ggattgcgcg aagaaccgcc
    14341 tccgccgaag aaacttgaga aaatatcctc aaaaccaccg aagccacctg ccccattgaa
    14401 accaccgaaa ccaccagctc caccaaaacc accattggcg cctgcagcac catactggtc
    14461 ataggcagca cgtttttggt cgtcactcaa agtctcatag gcttcttgaa cttccttgta
    14521 cttgtcctca gcaccaggct ccttgttgat atctgggtga tattttttgg aaagcttacg
    14581 ataagccttt ttgatttcgt ctgccgaagc gtttttggat acccccagac gatcataaaa
    14641 ttcagtattg ttcataattc aagatacaaa gggcgtcaaa cggacacagc catctaggag
    14701 ttttgacgac ggacgcttac gtcctagaaa aaactatctt tttggcacag tccgtagccc
    14761 gtgttcagtt acgaacaccc ttattccttt ctattgatgt tctgaatcga accaccattt
    14821 aggtcgggtt caattccttt cttttatatt tagtaagaaa ttctgaaacc cgtgttcagt
    14881 tacgaacact ctttgttcct ttctattgat gagacaaaac ccaaacaaat gagattccgt
    14941 ccctttttat cgaaaaacag aggctgggtt gcaacctctg caaataagta aattaacttt
    15001 attttgattt taaatatcct ataagtacag aaatatttat atatttttgt ctcttcttag
    15061 tatttgccta tataattcca attgatcata agaaatacaa ctactgtcca aatcatacca
    15121 attatgaacg gtattacaaa tttatatgtt tgtatttcta atgatatcat agctgatacc
    15181 atcgccgata caaatgcaga caacaatact gaggtaacaa aattccttac cgcttcatca
    15241 tttttgacac aactatcatg ctcagctaat ataatttctc tatatctagc taaatattct
    15301 attggaatat tatcaataaa atcttttgat gttctatagt tatcagcttg attacaaaaa
    15361 tcattataaa cttttcgtgt attttttaga tactcttcat ccaatacact catcttactt
    15421 ttccgtaaac tctccgtcta cgacgtcatc gcctgcgttt cctgttgctt gtgcgccttc
    15481 tgctccttct tgagcttgtt gcgctgctgc ggcttgttcg tagagtttaa cagcaagtcc
    15541 ttgagctttt tcgttcaatg cttcaagttt tgctttcatg tcgtccaagt tgttgtcttc
    15601 ttgagctttc ttaaggtcat caagggcagc ttgggcagcg tcacgttctg cgtcgaagcc
    15661 tttaccttca gtttccttga ttgtcttttc agtcgcaaag attgcttggt ccacttcatt
    15721 acgaaggtct acttcttctt tacgtttctt atcggattca gcgtttgctt ctgcatcttt
    15781 catcatgcgg tcgatttctt cgtcagtcaa acctgagttc gattggatga caatagtttg
    15841 ttctttttga gttccaaggt ctttggcctt aacagacacg ataccgttct tgtcgatgtc
    15901 aaatgttact tcgatttgag gaattccacg aggtgcagct gggatatcag tcaattggaa
    15961 gcgtccaaga gtcttgttat ctgctgccat tgggcgttca ccttgaagaa cgtggatatc
    16021 aacggctggt tggttgtctg ctgctgttga gaagacttgt gatttagatg ttgggattgt
    16081 agtgttgcga tcgataagtt ttgtaaatac tccacccatt gtttcgatac caagtgacaa
    16141 tggcgttaca tcaagaagga caacatcctt gacatcacca gtaatcacac caccttggat
    16201 agccgcaccc atagcaacta cttcatcagg gtttactgat ttgtttggtt ctttaccagt
    16261 ttcagcttta acagcttcaa caacggcagg gatacgagtt gaaccaccaa caaggataac
    16321 ttcgtcgatt tctgacaagc tcaaacctgc atctgaaagg gcttgacgaa ctggaacttt
    16381 tgtacgttca acaaggtcac gagtcaaatc atcaaatttc gcacgagtta aagtcatttc
    16441 caagtgaaga ggtccagcct cacctgcagt gataaatggc aagctgattt gtgttgaagt
    16501 tacaccagaa aggtctttct tcgctttttc agccgcatct ttcaaacgtt gcattgccat
    16561 cttgtcagta gacaagtcga taccgttttc tttcttgaat tctgctacca agtggtcaat
    16621 gattttttgg tcaaagtcgt caccaccaag tttgttgtcc cctgcagttg acaatacgtc
    16681 gaagacaccg tcacccaatt caaggataga gacgtcgaat gtaccaccac caaggtcaaa
    16741 taccaagatt ttttcttctt tgtcagtctt gtccaaacca taagcaagag ctgctgcagt
    16801 tggttcgtta acaatacgtt ctacttcaag accagcaatt ttaccagcgt cttttgttgc
    16861 ttgacgttga gcgtcgttga agtaagccgg aactgtgata acagctttgg ttactttctc
    16921 accaaggtag tcttcagcgt agcctttcaa gtattgaagg atcatagctg agatttcttg
    16981 tggagtgtat tcttttccat ttgcagaaac tttttcagaa gttcccatct tagatttgat
    17041 agagataact gtatctgggt ttgtgactgc ttgacgtttt gcagcatcac caacgatgat
    17101 ttctccgttt ttgaatgaga ctacagatgg agttgtgcgg tttccttctg ggtttgcgat
    17161 gattttgctt tcagttcctt caagaactgc aactgctgag tttgttgtac ctaagtcaat
    17221 accgataatt ttagacatgt gtttttctcc ttgttagtta attttctatt tttctttttg
    17281 atactcttct taagtggcga cagtggcgac gccgtcagag cttgacttcg tcagtctctt
    17341 tgactaaact ttgagcctaa ggtctcaaaa tttgcgcaaa tagcgccacg gcgaagagta
    17401 tcgtctttgg ttcgcttcgc tcactattac aaagcaaaac atattttatc tttcttcata
    17461 gtttattgtc gtttcggaca agttttctat tatgtaaatt gcgacacgag gagtcgaaat
    17521 cgattttatt tcgacgacga gttagtaagg aagctaggca aacgccatag caattgccgt
    17581 tttctgacga gttgctttag ctaccgtcag aattgccgaa tcgaacacgc cctaagctct
    17641 gagtaaaaaa gatagatttt cttgtgttca tcgaacactt cgttaatctc ctatttttac
    17701 tgcgagcttt ttacgggctt tgtatcttag ttatacacca ctaccattgc tgggcgtagg
    17761 atgcggtcat ggagtttgta gcctttttga aagacttggg cgatggtatc tactgggtgt
    17821 tcatcgtctg ctgggagagt ttggatggcc atatggtagt tatggtcaaa ttcgccatct
    17881 gctgcgattt cttcaattcc ttcttctttc aaagcgtgaa tcaagctttc ttgcaccatc
    17941 cccaagccct tcttcacatc atctgtcaaa ccttcaactg caagtgcacg ctcaaggttg
    18001 tcaagagatg gtaagattgc ttttgccaag tcctggctac gataacgttg caagttttga
    18061 cgttcttcat tggcacggcg ttggatattt tgcatttctg catgagcgcg aagatatttg
    18121 ttttcgaact catctgcacg ttcatttgcc aagtccaact cagacttttc aggagttgtt
    18181 tcttcagctg tttccacaac ttcctcttct tgaacttctt ctacttcttc attttttata
    18241 tcttgggcca tgttcgcctc ctttaatgat ttcaatctta atgtacttcg taatgattac
    18301 tgctgaggta gcggtaaaaa tctgtcaact tcatggtcaa aacacggttg accacattga
    18361 tttgattgat tagctgttgg taatccagat taactggacc gataatggct agaattccaa
    18421 ctccccgata aggaatgagg aacttactac taatcaccgc taggtcagct aaacaggact
    18481 cttgaccgtc tgcaacacga acattttgca tctgatcctc acgcaacccc tcacgaatct
    18541 ccaaggccac cttttgcggt tggtcaaaga actgataggc tgctagattg gcaaaattca
    18601 agagattgac cttgcccgcc atcacaatgt tttcgttgaa catttcctta aagatgtgtt
    18661 caaagagatc gatgacatta tccgttgttg taaagtaacg ctggataatc tgcggaatct
    18721 ccgtccgaat cttgtagtga atatctaaaa cggtgtgacc gaggaaacgt tcctgaatga
    18781 tgctcttcag tttcagcaaa tcctcctgca agaagttcct tggaatcaga aactgactag
    18841 taaccgttcg cgactcgtct agggtaaata ccgccaaggc tgtatgttgc cccaaaacaa
    18901 cgatatcaaa ggctgtcaaa cgttgcctgc tcggctcaac atccagtgcc actaccgtac
    18961 agccactcag gtctgttagc aagttagcag cctcttgcag aatatcctcc aatttgaaga
    19021 attcctgatc aaaggctttg acaatctcat atacctcatt ttcagccagt cggtcaaaat
    19081 ccagtgagtg tttcacatag tactgaaaac cagcaacact tggcatccga ccgcttgaag
    19141 tatgagcctt ctcaagcaac ccttgttttt ctagttccgc catgtcatta cgaatggttg
    19201 cactgctaga gttaatagac tcttgcaagg cttttgatcc gacaggttcg tgcgttttgg
    19261 taaagatgtc aataatcaga tttaaaatat cctgctgacg ctctgtaacc atctcatcac
    19321 tcctctctgt ctgatcaatt agcactcaat gcatccaagt gctaacttat gattctatta
    19381 tacaccctta gaagagaatg tcaagacaaa aactcaaaaa attagcactc ttttataaag
    19441 agtgctaaaa atcaatctga agacctagaa ccttgctatt catctactcg gtatttcctt
    19501 tttagtctga aataaccatg aattagataa gaaatcagaa aagcatataa aacaaaaata
    19561 agaaagaaag acatagaaag atcctctcta aacaaactca tacaaacaac aagaccacct
    19621 aagaaagtag ctatacagga acgaagtcta gatcgcataa cttcccattt gagcccctta
    19681 ctcatataga cttgatcctc tggaagtaaa tcagaagacg atttacgaag aatcgaacaa
    19741 gaacctgctc ctatcaattc ccaacctcta tctctaaaat cttgcagttc acgcttatgc
    19801 tctttaagaa atctagaatc atagatacga tagataacat cgtccggttg accttgctca
    19861 aaatagaaca aaccaaaacg actagttcta tacctccaac ctttcaaatg catctcatgt
    19921 aaatattctt ctttcttgtc caaatcaaca atggtgaaaa tccgaaattc tactctgcta
    19981 ttcattgtct taccccaaaa ttagaaaaca tgcctagcgt tatttattag ataattcttt
    20041 ccacttttga ctcaatctcc aaaaaatata agaaatctga atcgcaaaaa ctatcaataa
    20101 aacccaatct attatgaaaa tcaaaaacac ttcccaactg aaagaactac ctccagtgac
    20161 aaactttgag aaaaacggta gtagagctaa aaagagaagc aaaataggaa gcatccgcat
    20221 tgttaaaatc cgtttggcat aaaaaatctt tatttaaacg aaaatattat ggtaaaattt
    20281 acgccagttt ttgaacggct gatgtagata ttttatactt tcaaaatgtt taaatgtgat
    20341 tatttatttt tgaaaaatag ctcaccagcc cgactgaaag tgcttataaa tgataataag
    20401 tcgcctgccg aaaacagcga aaaatagcgg tgttatgcgg agataatctg acgcgatgcg
    20461 aaagtatatt gcatacttat tttcaacaat ttagcagagt atttttataa gtgtgatata
    20521 atagaagtat aatttgttct gatagtttat ttatggagaa gtagattttt agaatgcgga
    20581 gggttcaata tggttgagtt tataaagtct aagaaagaaa tgagtgagga ggatattaaa
    20641 gcaaatttca tcactcctgc tattgtatcc aaaggatgga aaaatggtga gcatatcgct
    20701 tacgaagaat acttcactga tggtcgaatt gaggttagag gagataaggc tcgtcgtaaa
    20761 gaaggaaaaa aatcagacta ttcactgtat taccaatttg gaactcgaat tgcaattgtt
    20821 gaggcaaagg ataataaaca cagcgttcga gcaggattac aacaagctat tgaatatgga
    20881 gagattttag atgttccatt tgtttattct tcgaatggtg atggctttat tgaacacgac
    20941 cgtatcacga gagaagaacg tgagctggag ttagacgaat tccctactcg tgaagaatta
    21001 ttttctcgta tgacgaagga aaaaggattg acgtacgaaa ttacagaagc tatctcaact
    21061 ccatactata cagacgcctt ctcaatgaaa acgccacgct attatcagca aatagctatc
    21121 aaccgtacta ttgaaacagt tgccagagga caaaaacgag taatgtttgt gatggcaaca
    21181 ggaacgggga aaacgttcat ggcttttcaa attattcatc gccttcgaaa agctggtttg
    21241 gctaaacgag ttttattctt agcggataga aacatcttag tagaccaaac gatggctgaa
    21301 gactttaggc cattcgaaaa ggtaatgacg aaaattacac caaaactttt gactgctcct
    21361 gaaaaattaa attcttttga aatttatcta gggctttatc agcaactaac tggtgaagat
    21421 ggaactgaaa cacattatca aaaatttgac aaagacttct ttgatttaat cgtaattgat
    21481 gaagcgcacc gtggttcagc taaggaagac agtaactggc gtaaggtgat tgattatttc
    21541 agttctgcga cacagattgg gatgaccgct actcctaaag aaaccaagaa tgcttccaat
    21601 acggaatact ttggtgagcc aatctatact tatagtttaa aacagggaat cgaggatggt
    21661 tttttggctc catatcgtgt tatgagggtt aatttagatg tggatgtgga tggttatcgt
    21721 ccagaaactg gaaaagttga tactaacgga caattaatag aagataggta ctacggcagg
    21781 aaagattttg ataaaaccat tgtcattgat gatagaacgc aaagagttgc caagtttgtt
    21841 tctgattata tgaagcaaaa caatgcacga tttgataaaa caattgtttt ttgtgttgat
    21901 attgaccatg ccgagcgaat gcgtgctgca cttgtaaaag agaatctaga cttagtccaa
    21961 gaagactatc gttatgtcat gcaagtaact ggtgacaacg ctgaaggaaa agctcaactg
    22021 gataacttta tggatgtcaa ttctaatttt cccgctattg taacaacgtc taaattatta
    22081 acgacaggag ttaatgctaa aacatgtcgt ttgattgttt tagactctaa tatccaatcc
    22141 atgactgaat ttaaacaaat tattggtcgt ggcacacgtc tttatcctca aaaggggaaa
    22201 gaatttttta cgattattga ttttcgaaat gttaccaatt tgtttgctga ccctgatttt
    22261 gatggtgagc cagtgaaggt gctggaaaca ggtgcgaaaa cagtcagtgg ttccacgccc
    22321 ggtttcgtag atgaggaagg tgacccagta gaaaaatata tcgttacaga caagcaggtt
    22381 accattctta attctactgt tcaagtattg gatgaaaacg ggaaactgat taccgaaagc
    22441 ctgaccgact acactcggaa gaatatctta ggtagctacg ccactttgaa cgattttatc
    22501 acagtttggc atacggcgga taaaaagaag cttatcttag acgaacttta taaaaaagga
    22561 gtttatctag atgctattcg agagtcggag ggaatatcag aacaagaaat cgatgatttt
    22621 gatttactcc taaaacttgc ctatggtcaa aaagaattaa ccaaaacgga acgtatcaat
    22681 aaactcaaac aaagcggata tttatataaa tatagtgagg aagcgcgtgc tgttttggaa
    22741 attttactga acaaatacat ggataaaggt attggagaac tcgaaagcat tgaaacatta
    22801 aaacttccag aatttcagat atatggtgga accttcaaaa tcatcaatac ttattttgga
    22861 gataaaaaac gatatttaca agcaattaaa gaattggagc aagagctatt tacagtagct
    22921 taatgaaagg aaagtatgtc aattacatca tttgtaaaaa gaattcaaga tatcactcga
    22981 aacgatgctg gtgttaatgg tgatgctcaa cgtattgagc aaatgtcttg gttattattc
    23041 ttaaaaattt atgatagccg tgaaatggtt tgggaattag aagaagacga gtatgagtca
    23101 attatcccag aggaattaaa atggcgaaat tgggctcatg ctcaaaatgg ggaacgggta
    23161 ttgacaggcg atgaattact tgattttgtc aataacaagt tattcaaaga gttgaaagag
    23221 cttgaaataa cttcaaatat gcctattcga aaaacgattg ttaaatcagc ttttgaagat
    23281 gcgaacaact atatgaaaaa tggcgtcttg ttacgccaag tcatcaatgt tattgatgaa
    23341 gttgatttca atagccctga agatcgtcat tcgtttaatg atatttacga aaaaattctt
    23401 aaagatattc aaaatgctgg gaactcagga gaattttata cgccacgtgc agcgactgat
    23461 tttattgccg aagttcttga cccaaaactt ggagaatcaa tggcagacct tgcttgcgga
    23521 acaggaggct tcttgacttc gactctgaac cgtttaagta gtcaacgtaa aactagtgaa
    23581 gataccaaaa aatataatac agctgttttt ggtattgaaa agaaagcatt tcctcatctt
    23641 ttagcagtta caaatctgtt tcttcacgaa attgatgacc ctaaaattgt tcatggaaat
    23701 actttggaga aaaatgttcg tgaatatacg gatgatgaaa aatttgacat tattatgatg
    23761 aatccacctt ttggaggatc agaattagaa acaataaaaa ataactttcc agcagaatta
    23821 cggagttctg aaacagctga tttatttatg gctgtcatta tgtatcgttt aaaagaaaat
    23881 ggtcgtgttg gagttatttt acctgatggt tttctatttg gtgaaggtgt aaaaactcgc
    23941 ttgaaacaaa aactggtaga tgagttcaac ttgcatacga ttattaggtt gcctcatagt
    24001 gtctttgcac cgtatacagg aatccatacg aacattcttt tctttgataa aacaaagaaa
    24061 acagaagaaa cttggtttta tcgtttagat atgccagatg gttataaaaa tttctcgaaa
    24121 actaagccga tgaagtcaga acacttcaat cctgttcgtg actggtggga aaatcgtgaa
    24181 gagattctgg aaggtaagtt ctacaaatct aaatcattta cacctagtga attggctgag
    24241 ttgaattata atttagacca gtgtggcttt ccaaaagagg aagaggaaat cttaaatccc
    24301 tttgagttga ttcagaatta tcaagcggaa agagcaactt taaatcataa gattgataat
    24361 gtattagctg atattttgca gttgttggag gacaaataat gacaccagaa caacttaaag
    24421 caagtattct ccaaagagcg atggaaggga aattagtgcc gcaaaatccc aatgacgaac
    24481 ctgcaagtga attattaaag agaattaaag ctgaaaaaga aaaacttatc agtgaaggaa
    24541 aaatcaaacg agataaaaag gaaactgaga tatttcgtgg tgatgatggg aaacattatg
    24601 ggaagtttgc tgatggaagc actcaagaaa ttgatgttcc ttatgatatt cctgatactt
    24661 gggagtgggt gaggttttct acattggttg aaattgtcag aggtggctct ccacgaccaa
    24721 tcaaagatta tcttacttct gaagtagatg gaataaattg gataaaaata ggtgatactg
    24781 aaaagggtga aaagtatata aataatgtta aagaaaaaat caaaaaatca gggcttaaca
    24841 aaactagatt tgtaaaaaaa ggtacatttt tgttaactaa ttctatgagt tttggtagac
    24901 cttatatttt gaatgttgat ggtgcaatac acgatggatg gttggctatt tcgaactatg
    24961 aaaactcatt aaataaagat tacctattct atattctttc atcaaatgta gtttattctc
    25021 aatttctatc tctaattagt ggagctgttg tgaaaaactt gaatagtgat aaagttgctt
    25081 ctattcttat ccctctccct ccgctagctg aacaacaacg cataatagaa gcaatcgaat
    25141 cagctttaga aaaagtagat gaatatgctg aaagttataa tagactagaa cagctagata
    25201 aaaaatttcc agataaacta aaaaaatcta ttcttcaata tgctatgcaa ggaaaattag
    25261 ttgaacaaga cccaaatgat gaatcagtcg aagttttact tgaaaaaata cgagcagaaa
    25321 aacaaaaact ctttgaagaa ggcaagatta aaaagaaaga tttggacatt tctattgttt
    25381 cccaaggaga tgataactct tattatggga atatacctat gaattgggtt gttataaaaa
    25441 taaaagatat tttttcaatg aatacaggtc tttcttacaa gaagggcgat ttaagcatta
    25501 ataataaagg tgttagaatt atacgtggtg gtaatattaa gcctttagaa ttttctctgt
    25561 tggataacga ttactacatt gatacacaat tcatctcctc tgagcaagtt tatttaaaac
    25621 ataatcagct aataacacct gtatcaacct ctttagaaca tattggaaag tttgcaagaa
    25681 tcgataaaga ctatgatggt gttgtggctg gtggatttat tttccaatta acaccattcg
    25741 aaagttcaga gattatttca aaatttctat tatttaactt gtcctctccg ttattttata
    25801 aacaattgaa agcaataact aaactatcag gtcaagcttt atataatatt cctaaaacta
    25861 cactaagcga gctattaatt ccgttagctc cttttgagga acaggaactt attactcaaa
    25921 aagttgagaa actttttgaa aaagtaaatc aactttggaa atgattcttt tcatctcttc
    25981 atgattagaa atagggatta ataattcgga gatactggta ctatttaatg ttttcccttt
    26041 gatagcatct tttgaatcac ctaaagtaga gataagtggc aaaaatatca ttaagtaatc
    26101 tctgataata ttttctttat tagcataggg gaatatcgat ataatggctt cattatgagt
    26161 ggcaggaata tccaatatgg caacttttcc aatagataat ttaaaactca ttaataaagt
    26221 tcctttaggt gaaatgtcta ttttctttga ttttaatgct aatttagaaa tagattctct
    26281 cgtattagtt acataaccag atataggcat atctgatata gatacccaag gtatttcagt
    26341 tccccaaaaa gtagcttcac tgcgtggagg agtttttcct attctgaagt taactaggct
    26401 agcaaattta atatatctcc atgcttctgg gatttcatat ataggataag aggttgtttc
    26461 gtctttattc ccataataag agttatcatc tccttgggaa acaatagaaa tgtccaaatc
    26521 tttcttttta atcttgcctt cttcaaagag tttttgtttt tctgctcgta ttttttcaag
    26581 taaaacttcg actgattcat catttgggtc ttgttcaact aattttcctt gcatagcata
    26641 ttgaagaata gattttttta gtttatctgg aaattcttta tctagctgtt ctagtctatt
    26701 ataactttca gcatattcat ctactttttc taaagctgat tcgattgctt ctactattcg
    26761 ttgttgttcg gatagtgggg ggagagcaat taataataga ttaaaattat aatcattgat
    26821 tgcaggataa cttgttccag tagatttatt attaacacga ttgataaaat tatctgataa
    26881 taaataatat ttcaaatatg tttcgttaag taaagtatcc aaaacaataa atgctgtact
    26941 agctatcaaa tactctttaa gttctctaac tacagcaata ttttttagat atggtctaac
    27001 tgttgaaaat aagacactat tctgcgaaac taattttcta gcacgggaag gcgcttgttc
    27061 aggtgaaaga tattgtagat ttttgtagtt gattatgttc ttttttctat caatactaga
    27121 cgtatctata tacctaaagg atttctctgg cttattttgc ccaaaattcc aataaattga
    27181 ttttatcctc acccactccc aagtatcagg aatatcataa ggaacatcaa tttcttgagt
    27241 acttccatca gcaaacttcc cataatgttt cttatgtgct tcaagtatat aaaaaggcgt
    27301 aaaaatacgc ctatagataa tggggttgaa ataggtttat tgttgatgag attgtagata
    27361 attcaatttt ttacttccaa tcgaatattc aaaacctcca ccttttctgc ctgtaattgt
    27421 tcatcataaa attcaatatc ttcaggattt tccccttggc aacctcggca gaaatattct
    27481 tccgctcgat caggattcaa aaatcgacaa gcacaaacaa aacagtcgcc atcatcattt
    27541 attgagataa tatagtagat tgaaataaga tgtaaacaaa tcgattagga aagttaaatt
    27601 agtttctaga aatttttagc agatgtagtg tactattcta gtctcaattt actatggctt
    27661 caaatatatc tttcgaaaaa atatttacag atgtgtaatt ttgaagcttg caaaagttag
    27721 taaacttgta gatttcgatt tgaagtaact tgttttcttg cccgatattg tttttgaaat
    27781 tgaatttttc catagtgact ccttgatttt cttctacacg tctgatgata aatctaattc
    27841 gcaaaagagt caagaggatt tttcgaaaaa taaatagcga ccgaaatcgc tattttaagg
    27901 gttataggta tttgatggct tagactgctg tgtgactgtt tacccacagg caatctttc
//
LOCUS       DBEJZV010000024        27367 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.24, whole genome shotgun sequence.
ACCESSION   DBEJZV010000024 DBEJZV010000000
VERSION     DBEJZV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27367
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.24"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(59..853)
                     /gene="pflA"
                     /locus_tag="ACL3S0_001416"
     CDS             complement(59..853)
                     /gene="pflA"
                     /locus_tag="ACL3S0_001416"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGR1312315.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(979..2229)
                     /locus_tag="ACL3S0_001417"
     CDS             complement(979..2229)
                     /locus_tag="ACL3S0_001417"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGR1312316.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTPAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(2296..3123)
                     /gene="purR"
                     /locus_tag="ACL3S0_001418"
     CDS             complement(2296..3123)
                     /gene="purR"
                     /locus_tag="ACL3S0_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGR1312317.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(3390..4331)
                     /locus_tag="ACL3S0_001419"
     CDS             complement(3390..4331)
                     /locus_tag="ACL3S0_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGR1312318.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(4321..5577)
                     /gene="rmuC"
                     /locus_tag="ACL3S0_001420"
     CDS             complement(4321..5577)
                     /gene="rmuC"
                     /locus_tag="ACL3S0_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGR1312319.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(5579..6241)
                     /locus_tag="ACL3S0_001421"
     CDS             complement(5579..6241)
                     /locus_tag="ACL3S0_001421"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGR1312320.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(6204..6860)
                     /gene="rpe"
                     /locus_tag="ACL3S0_001422"
     CDS             complement(6204..6860)
                     /gene="rpe"
                     /locus_tag="ACL3S0_001422"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGR1312321.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(6871..7749)
                     /gene="rsgA"
                     /locus_tag="ACL3S0_001423"
     CDS             complement(6871..7749)
                     /gene="rsgA"
                     /locus_tag="ACL3S0_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGR1312322.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKKELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(7751..8623)
                     /gene="rsmA"
                     /locus_tag="ACL3S0_001424"
     CDS             complement(7751..8623)
                     /gene="rsmA"
                     /locus_tag="ACL3S0_001424"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGR1312323.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMTFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(8754..9062)
                     /locus_tag="ACL3S0_001425"
     CDS             complement(8754..9062)
                     /locus_tag="ACL3S0_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312324.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(9055..9696)
                     /locus_tag="ACL3S0_001426"
     CDS             complement(9055..9696)
                     /locus_tag="ACL3S0_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312325.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(9698..11728)
                     /locus_tag="ACL3S0_001427"
     CDS             complement(9698..11728)
                     /locus_tag="ACL3S0_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR1312326.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFIDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(11805..12101)
                     /locus_tag="ACL3S0_001428"
     CDS             complement(11805..12101)
                     /locus_tag="ACL3S0_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR1312327.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(12421..13320)
                     /locus_tag="ACL3S0_001429"
     CDS             complement(12421..13320)
                     /locus_tag="ACL3S0_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1312328.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(13392..13952)
                     /gene="rnmV"
                     /locus_tag="ACL3S0_001430"
     CDS             complement(13392..13952)
                     /gene="rnmV"
                     /locus_tag="ACL3S0_001430"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGR1312329.1"
                     /translation="MKERISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(13952..14725)
                     /locus_tag="ACL3S0_001431"
     CDS             complement(13952..14725)
                     /locus_tag="ACL3S0_001431"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGR1312330.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALKLVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(15030..15923)
                     /locus_tag="ACL3S0_001432"
                     /pseudo
     CDS             complement(15030..15923)
                     /locus_tag="ACL3S0_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226469.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor protein"
     gene            complement(16207..16341)
                     /gene="rpmH"
                     /locus_tag="ACL3S0_001433"
     CDS             complement(16207..16341)
                     /gene="rpmH"
                     /locus_tag="ACL3S0_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGR1312331.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(16486..17700)
                     /locus_tag="ACL3S0_001434"
     CDS             complement(16486..17700)
                     /locus_tag="ACL3S0_001434"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR1312332.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(17856..18150)
                     /locus_tag="ACL3S0_001435"
                     /pseudo
     CDS             complement(17856..18150)
                     /locus_tag="ACL3S0_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            18312..18764
                     /locus_tag="ACL3S0_001436"
     CDS             18312..18764
                     /locus_tag="ACL3S0_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGR1312333.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(18799..20187)
                     /locus_tag="ACL3S0_001437"
     CDS             complement(18799..20187)
                     /locus_tag="ACL3S0_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR1312334.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            20253..21215
                     /locus_tag="ACL3S0_001438"
     CDS             20253..21215
                     /locus_tag="ACL3S0_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGR1312335.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPYIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(21244..21582)
                     /locus_tag="ACL3S0_001439"
     CDS             complement(21244..21582)
                     /locus_tag="ACL3S0_001439"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312336.1"
                     /translation="MNTIERTRRLIKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDETNEVSSKHVFEVVDETNEVSSKHVFEVVDRTDEVSSKHVFEVVDETDE
                     VSNHTYGKAT"
     gene            complement(21646..22656)
                     /gene="ccpA"
                     /locus_tag="ACL3S0_001440"
     CDS             complement(21646..22656)
                     /gene="ccpA"
                     /locus_tag="ACL3S0_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGR1312337.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(23081..23680)
                     /locus_tag="ACL3S0_001441"
     CDS             complement(23081..23680)
                     /locus_tag="ACL3S0_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1312338.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLMLQPDVESVFQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERNIADLMQTLHTVLEGRKEYSPELMEVVMMHPNPLTEQEIAVLKGIAQGFSNQEIA
                     DKLYLSNGTVRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(23681..24778)
                     /locus_tag="ACL3S0_001442"
     CDS             complement(23681..24778)
                     /locus_tag="ACL3S0_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HGR1312339.1"
                     /translation="MLERLKRIHYMFWISLIFMIFPILSVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILTFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKSSLTQEL
                     ESTASMILLELVTNIIKHAKASKVYLKLERTEKELILTVRDDGCGFASISGDELHTVR
                     NRVFPFSGEVSVISQKHPTEVQVRLLYKERK"
     gene            complement(24778..25515)
                     /locus_tag="ACL3S0_001443"
     CDS             complement(24778..25515)
                     /locus_tag="ACL3S0_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312340.1"
                     /translation="MKRWLALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTGFSMMSTAIFSFPAVLHTDKMNNWQKILRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLILGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPVSLFPDWMQAIGKRLPSYQLMELIKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(25517..26401)
                     /locus_tag="ACL3S0_001444"
     CDS             complement(25517..26401)
                     /locus_tag="ACL3S0_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312341.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEVDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLVQAGCGIQEIEV
                     NNRSLLDTIFEETQKGDN"
     gene            complement(26388..26582)
                     /locus_tag="ACL3S0_001445"
     CDS             complement(26388..26582)
                     /locus_tag="ACL3S0_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312342.1"
                     /translation="MKKGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(26579..26785)
                     /locus_tag="ACL3S0_001446"
                     /pseudo
     CDS             complement(26579..26785)
                     /locus_tag="ACL3S0_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         7901 a         6344 c         5029 g         8093 t
ORIGIN      
        1 tttgctcttt gattttcatt gagtatcaaa agcccgatgt ttccatcagg cttcttttct
       61 atccatgtac acgtttcata taatcttgat aactttcggt atccatgagt tttttagcgt
      121 tcttgacgcg atctgctgtt ggtggtttga ctccttcgag ggaatatgga attccaagtt
      181 cacgccactt gaactcaccc atggtgtgat aaggtagaat ttcaaactta tcaacatttt
      241 tgagggtctt gacgaactta ccaagttcaa tcaagtcatc atctctgtct gtcaatcctg
      301 gaactagcac gtggcgaatc cagacaggtt ttccaatatc tgatagatac tgggcacaag
      361 ccaagatatt tttattagtt tggctagtga caatcttgtg ctgttcttcg ttgatttcct
      421 tgatatccaa aagaaccaag tcagtgacag ccatgagttt gtcaaacttc tcaaggtaac
      481 gtggtttatt acggaaagga agagcacagg tatccaaggt acagtggatt ccttgttcct
      541 tagccttggt gaagagagca atcaggaaat caatctgcaa gagagcttct cctccactga
      601 ctgtaatccc acccttattt ccccagaaac cacggtagcg caaggcctct gtcaagacat
      661 catctaccgt ccgttcacgt gacttattgg actccatagc ccaagtgtct gggttgtggc
      721 aatactggca acgcatgtga cagccctgca aaaagacaat aaagcgaata ccaggcccat
      781 ctactgaccc aaagctttct gtcgaatgca ccattcctgt cacttgtcca taatcaattg
      841 tttcttcaga catatcgtta ccttccttga aaacgtttta tagttttatt atatcacgac
      901 ttgaaggaaa aacaagattt ttgcctattt tttagaaagc aatctgtttt tcaatttcat
      961 tttcaatcta ttatcagatt attcttcaaa atcgaagcca tataaggttg caaaatagtc
     1021 ctcagggcgc tctgcacggc ggatttgacg ggctttacct tcttcggtat agaggatttc
     1081 cgcagaacgt aatttggcat tatactggta gcccattgaa aatccgtggg cacctgtatc
     1141 atgaattacc agcaaatcac cgatttctgt atgaggcagt tcgcgattga ctgcaaattt
     1201 atcattgttt tcacagagtg aaccaaccac atctaccgct tcagctggtc catctggatg
     1261 ggtcacgttg ctaatatgat ggtaagctcc gtacatagct ggacgcatga ggttgactgc
     1321 tgaggcatcc acacctagat aggtacggta ggtttccttc ttatgagtca ctcttgtgac
     1381 tagagcaccg tgaggtgcca gcataaaacg acccaattcg gtgaaaatct tgacctgacc
     1441 aagacctgct ggcgtaagga cctcttcata caccttacga actccctcac caatcaaggc
     1501 gatatcgttc ggctcctggt ctggacgata attaacacca ataccgccag aaagattgat
     1561 aaagtctagc caaatgccca acttttcctt gatttcaaca gccagttcaa agagctgacg
     1621 agccaactct ggataataga gatgggtcac ggtattggac gctaggaagg agtgaagccc
     1681 aaaagtcttg gctccttttt ccttcaagat agcaaaggct tcaaagagct ggtccttggt
     1741 catgccaaac ttagcctccc caggattatc cataatgtct gtccccagtt caaaaacgcc
     1801 tccaggatta taacgacaag agatgatttc tggaatgcct gctactctct ccagatgttc
     1861 aatatcttca aaggcatcca agttaatggt cgcacccaat tcacgtgcat aggcgtattc
     1921 cttgtctggc gtgttgttgg aagagaacat aatctcagaa cccagaaagt ccagtttatg
     1981 gctcatcaaa agctctacat aactagagca gtccacacca caaccttctt cttggagaat
     2041 tttcaaaata gctggagttg gagtagcctt aactgcaaaa tattccttaa agcccttgtt
     2101 ccacgaaaaa gcttggttga cggctcttgc cttctcacga atccccttct catcatacaa
     2161 gtgaaaggga gtcgggaact cggcaacaat cgcttctaac tcttctctat tgataaatgg
     2221 tgttttcata agcttccttc tattctgttt gcaaagaaag gctgggacaa tcgttccaac
     2281 ctttagttct atctcttatt tatcttcgtc aaagatattg ccaacctcaa catcgatggc
     2341 ttggttcttg acatcaatat tggttacctt caagagtgac ttgtagtcaa actgcttttc
     2401 acgttcttct tgggcattgt ccgcaaagac cgctacacct gccagttctg agtcgaactc
     2461 gcgcaagaga ctaatcatac cattgaccgt tccgccacct ttcaagaagt catccacaat
     2521 caagacacgg ctgcctgcct taagactacg ttttgaaagg aacattttct cgatacggtc
     2581 accacttgaa cctgaaacat agttgacgct aacagttgaa ccttcggtaa ttttcaggtc
     2641 acggcgcaca atgacaaaag agacattgag gacattggca actgcatttg caagtggcac
     2701 acccttagtt gctacggtca taaccgcgtc aattttttgg tccataaagc ttttggcaat
     2761 aatacgacca atatttttca agatggctgg tgtgctaagc aaatcagaca gatagatata
     2821 accacctggc aagatacggt cactttctga caacttggta cgcaagtctt caaccatttc
     2881 cttagcatcc tgactcgaaa tagacggtgt gaagatgaca cctccgccag ccccagtcac
     2941 tgtctggata tgaccgattt caatttcctc aaaggcgcgt ttgataatga cgatatcttc
     3001 tgagatggat gatttagcag actcatactt ttcagcaaaa gtattgagac tagttagttt
     3061 ataaggatta ttaatcaaat agttggaaat gacaaccatc cgatcacttc ttcttaattt
     3121 catttctatt tcctattcca tttttattca aaaaatcaaa aagcaaacta gaaagctggt
     3181 cgctggtggt tcaaaacact gttttgagat tgtcaataga actgacaaac cctgtaatat
     3241 acctgcatat atacatacga caaggcgata ctaccctagt ttgaagagat tttcgaagag
     3301 tattcatttt tgtcttttac ttattatacc atattcacat aaaaaaacga acattcttat
     3361 cctaaaaaat gctcattttt cttaaattat taatctaaat ctggtttata gaaggaacga
     3421 ttatccatag cgaagatttt attggtcatc tctcctttat ccaccaaagc aagagctgtt
     3481 gacatcatca tcatgcttgc atccagattg tcaatcatat ggataatctc tgcttccata
     3541 atgcgtggac ggactgggct tccatactca agcaagccgt ggtgactgag gatgacatga
     3601 cgaagcaaaa cgacttcttc cttggtatca tcgatgccga gttccataac tgtcttggta
     3661 atttcgctat caatgagagc gatatgtcca agaagattac ctcgcactgt gtactctgtc
     3721 tggtctggcc ccgtcaactc gataacctta gctaagtcat gcagcataat ccccgcatag
     3781 agtaagctct tattgagctg aggataaact tcgctaatag cgtctgccaa acgtaccatg
     3841 gtcgccgtat gataagccaa gcccgtttca aaggcatggt ggttggtctt ggcagctgga
     3901 taggagtaga attccttatc atacttggtg tagagatttc ggacaatccg ttgccagaca
     3961 ggattttcaa ttttgaaaat catttgcgac atgtagtcac gaatttcctt gacatcaact
     4021 ggtgacttga ccttgaaatc ggctgggtca ttgggttcac cagcttgagg caggcggaga
     4081 gtaatttgat tgacttgagg ggtattgtta taaacttctc ggcgtccttt catgtggaca
     4141 accttacctg cggtaaaggc ctcaatgtta tgaggttggg catcccagag cttcccatca
     4201 atctcgccac tatcatcttg gaaggtaaag gctaggtagt ttttcccagc tcgagtttgc
     4261 ctcaggtcag ctgatttgat taggtaaaag ccttcaaata gctcatcttt tttcatgtga
     4321 ctaatcttca tattcttcct cattttcttg aaaatggagt agatcaagcg caggctcgcc
     4381 ttctgacaac tcaatgtgac ggagcgtccg ctcgatagct atggtacgac ggtttaataa
     4441 ttcatcaata ttgccagagg catgttggag atgtttttgt gccttgacca gaataccacc
     4501 aaacttgcca aactcggtct tgacactggc aagagtcttg ctgatatggt cggcactctt
     4561 ttggatatta agggtcttga aaccaactga tagggagtta agaagggctg atagggtact
     4621 tggtcctgca acaataatct gttcttcccg tctcaaatca tcaaagaaga ccggattgcg
     4681 cacaatctct gaataaagac cttctgtcgg aacaaacaag attccaaagt tggttgtccg
     4741 aggcggtgct atgtacttgc tcttgatatc cttggcaaag cgcttgacgc ttgctaggag
     4801 tgacttacga cagcgttcaa tctcatcctt gtcacctgtc tcataggctt cttccaagcg
     4861 gtaataatct gccagtggaa acttagagtc aattggcaga tagacgtatt cttggtcgcc
     4921 ttgtccgggt aacttgatgg catactccac tcgttcacta gagttttcaa ccgttgcgta
     4981 ttctcgttcg tactgggcag gtgtcatgat gtcttcaata atttgcccca gttgcaattc
     5041 tcccagaatc cctcgcgtct tggttccaga gagaaccttg ttaagagctc cgacatcacg
     5101 ggcaactgtc tgcatttctc caaggccacg attgacagac tccagttgtt tagaaactgt
     5161 ctcaaaggaa gcctgtaagc gtgtctgcaa ggtcttttct agtttttcct cgaccgtctg
     5221 gcgcatttgt tccaaacgtt gctcatttga ttcctgcaag gcttggagac gttggtctgt
     5281 cttgtctcta gtttggagga gattatctgt catttcttga cggacttggg tcagaccttg
     5341 gtgcaattca atccgcactt cttgcaaacg gtcgctgaca accacttcca aatctttttg
     5401 gtctaactgg ctggcttgtc tggcttggtc aaagcggtaa tccaactggt ctgacaaatg
     5461 atctgcctga tcctccaagc tcttacttaa gtgtttctcc tgcctatcct gcctttgcca
     5521 aatcagaaaa agaccagcta ggttggcaat taataataga ataagtaaac tttccatcct
     5581 acctcctgtc cttgctatgc agtacgacca cataaccatc tgggcaagtt accgacactt
     5641 ccctatctat atattcgtta gaagcgtaca cttttttaaa gaaaaaattc tcctctgtca
     5701 actcatactt ggctccaaga atagtcagct ggctatcccg aactggcata aaggctagat
     5761 agtcgtagtc tgaacgaggt tctagctgac tggtcccttc tgaacaatag gcaatcaaat
     5821 tttgcccatc ctcaatttct atttgacgca tatagggtgc caacttagga ttgctaggta
     5881 gaaagacatt ggccaacata tggtcaatac ggccacccaa ggcaccgaaa atagtgacct
     5941 cagcctgagg attttgttca aagatggtta agagagccaa ttccagatct gtatcatcct
     6001 tttctggtcg tgcttggaca aaatactggg cacgtttttg aatcacctgt cgctcttctt
     6061 ccgtcacaga atcaaaatct ccgactgcta gagcaagagg taagtcttct tccaagaccc
     6121 agagcgagcc tcgatccacc ccaacaaaag catcaaaatc tgtccgataa tgaccgcggt
     6181 ttccgcctgc aaaaactgca accctagtcc agttgttttc tgagagtttg tactcgctca
     6241 ttgacttctc ccttaaagac ataggaacct gctacaaaaa cagtcgcacc agcttctttg
     6301 gcttgggcaa tagtttggtc atcaatccca ccatccactt cgatttcaaa gttcaaacct
     6361 ttttcctcac gaagagcaac caactcacga accttatcca tggtttctgg cagaaaggct
     6421 tgcccaccaa aacctggatt aaccgtcatg actaaaactt ggtcaactag atgaaggacg
     6481 tgcttgatgg cttcaactga tgtgccagga ttgataacga ctgaaggctt aactccgagt
     6541 gaacgaattt tttggagggc gccatgaata tgaggcgttg cttctacatg gatactgatg
     6601 atgtctgcac ctgcacgcgc aaaatcttcc agatgatgct cagggtttga caccatcaag
     6661 tggcaatcga aaaccatctt actatgagga cgaaggctct cgaccacacc tgcaccaaaa
     6721 ctgatttgcg gtacaaaatg actgtccatg atatcgatat gggcatattc tgccccagtt
     6781 gcttctagac gtttgatttc acgttcaaag ttggcataat ctgctgccag aattgacgga
     6841 gcaatcttgt attgagacat aggtttctcc ttattttgga atttttttgc tgactttttt
     6901 ataggtttct ctacgatttt caatttcact aaggaattgc aggtaattgt caaaacggaa
     6961 ggttgcaata acaccctctt caacagctgg tttgacggca caagacggct catgggtatg
     7021 ggtacaagta cggaacttac aatctcggct aacagtagca atctctggaa aggcctgatt
     7081 gaggtcttca gcccttgata cttcatagtc cagagatgaa aagcctggtg tatctgcgat
     7141 tttacccccg ttgagattgt aaaaactaac agctcgagtg gtatggcgcc cgcgacccag
     7201 actgtctgaa atttctcccg tttcaagatt aaggtctggt acgagtttat tgagaagagt
     7261 tgacttccca acacctgtct gccccataaa gaccgtaacc ttgcctgtta acaaagacag
     7321 gagttccttt ttactggtca caaagtcata gccgatgtca ccataggtct gccggtaaaa
     7381 atccagttct cccctatctt ccaacaaatc cattttggaa atatagacaa tgggatggat
     7441 gcccttgtgc tccaaaagaa ccaagaaacg atccaacaaa ttgctgttaa aatcaggttc
     7501 cttgacggac atgattacta cagcttgatc gatattgaca ataggcggac gaaccagact
     7561 gtttttccgt tcgtgaattt ttaggatata gccttctgaa ttttcctcgg cagagaaatc
     7621 tacccagtcc ccaacataag gggtatggcc ttttttacgg aaattcccac gcgcgcgtgt
     7681 ttgataaacc tggccatcac tctccacata gtagaaacct gccaaggctt taatgatttg
     7741 tccctgcatc ttagagtcct tgccctttaa gtgcgtctgc tagaccggca aattctgcca
     7801 agctgagagc ttccccacgc acacttggtg acaagcctgc ctggtccaaa gccttggtca
     7861 gcttgtcctt gacctcttca gtcttaccaa agtaacctgt caagttattc cacaaggtct
     7921 tacggcgatg ggtaaaacta gccttggaaa ccttaaagaa gaagttctca tcttccactg
     7981 ctacagctgg ctctggacgg cgcaccattt tcaagatggc tgaatccaca tttggcgctg
     8041 gcacaaagac cgtacgaggc acgataaagg caaccttggc tgtcatgtaa tactgcacgg
     8101 cgatagacaa gctaccgtaa gccttggtgt taggctgggc tgaaatgcgg tccgctactt
     8161 ctttctgcat catgaccaca aactcactaa aaggaatgcc actctcaatc aagtgcatga
     8221 gaataggcgt cgtgatgtag taaggcaaat tagccactac cttgattggc aggtcaggat
     8281 ttttaaaatt ctggatatgt tgcgccaaat caaccttgag aatatcttcg ttaactacgg
     8341 tcacattatc aaaatcacgc agggtatctg ccaaaattgg caccaaacgg tggtcaatct
     8401 caaaagtcat gacttgggct gcacgctcag ccagaaactc cgtcaaggca ccaatacctg
     8461 gcccgatttc gatgacattg acctggtcat caatttcagc cgtatccaca attttttgaa
     8521 ggatattggt atccgtcaag aaattttgcc cgaaggactt tttaaaggta aaaccgtgac
     8581 gctccagcac tgccttggtc acgctataat ctgcaattct catctattct cttttctatt
     8641 atctgttact actattgtaa cacattcccc ttgtattttg ggaatgaaaa tcataccaaa
     8701 aaactatctt tcctcatgaa gaaagatagt cttggaaatc tttaaaagtg gccttaacag
     8761 ttctctcgaa acatgcgttc aaaaaaatca gcttcttgat aacttcgatt ttcaggtagg
     8821 gtcaaatcca catcctcctc cacatcatcc actgtcagtt caaccgtctg aggtaaattt
     8881 ttcaaacgat aatgcttttg cctttgccct tcaatactag caaaatcaag caaatagcca
     8941 tgcactcgga tttgaaccaa aaggagatga ttggtcatat tttccatgat gaggatatct
     9001 tctaaaccac ctctggcact aggataatca gataccctgc gaatacggat tttttcacac
     9061 atgagcaagt ttcctcatat caatgatttc atcagcctta ttccagacta ggggattatg
     9121 ggtcgcaatg atgataattc gattttcatc tttcaaatcc accaagagat tcataacctc
     9181 ctctgaattt tcaggatcaa gagctgctgt tggttcatct gccaaaatca agggtggatt
     9241 tttcaaaata gtcttagcaa gggcaactcg ttgggcctct cccccagata aagtatagat
     9301 tttttgttct aaatccaaat accctagatt aactttttct aaagccccca cttgcctttc
     9361 caaacgttct acttttgaga ttttctgacc aacaaaaccc aaatccaaat tttctttgat
     9421 tgattggttt tctaagaggc caaaattttg aaagagatag cccatctgat ctcgaaaata
     9481 ctcacgagtg ggaatggttt ttaaatcttt cccctgatag agaacccttc ctccatctat
     9541 cttttctagc tttcccaaga tattcagcag cgtcgtcttt ccgcttccac tctttccgat
     9601 taaggcataa accttgccct tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc
     9661 attaaatttc ttttccaatc cttgaatatc aatcatctta ttttcctttc aatactgcca
     9721 tgctaccagc ttcttctttt ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa
     9781 acaaagctac aactagagcg ctaatcaaac catctcttgt caaaatacta gataggacta
     9841 ggccaagcaa gagaactcct ccttgcgcca gtaaatactt gccatgaagc tcatagattg
     9901 tcataccagc aagacgttta atcataagct cccgtctgaa ctgctcaaaa tagagaagat
     9961 tcatggaatc aaataacaag atagccgtag acagggtcaa aatcgtccca ataaggagag
    10021 agtaaaactc cacccgtttg tcatttagta ccttggcaaa aaatagctgg ctttttacca
    10081 agtaagaaac cttgtgatac agaccttgct cttttagagc tgtgatgctg tctccatatc
    10141 gatctagttt caaggcacta ttagccgtag ttccccacaa catccctgca acaggtcttg
    10201 ttccagtcgc ttgcggcgtt agaactacaa taatcggatc ttttaggtac tggcgtgttg
    10261 tcttgtaccc atcattatag aggaaacgtt cctgtcctgt ttctgtaaaa gctagcctta
    10321 cctgtgggaa gtagtgtttc tgactcgtca cttctacact ttcagatgaa aagttttgca
    10381 ggtaatctgt aaacaatcct tggtagtagg cagactgctc ccgcaagctc tcaggcaaga
    10441 tcagcccaaa ctctccctca gacaagtttt gcatcttgtc aataaactct gaagaaacgg
    10501 taatcttttc ttctatcaga tagcgcggcg agacatagat aacattccct gacggtgtgt
    10561 agtcactgag acgattgcca tctaggtcca cttctgctcc atctgagaaa ttgtcaacat
    10621 tgctcataat ataaaaagag tctgtattgg ctaaccgttc ttcagtaaat gtctgccact
    10681 cacgattatc cttacgcgtt ccttcttcat cggcaaatgc actagaccaa ccaaaggata
    10741 gacggtaacg gtctgaggac tggctccatt tattgctagc tctctccatt tcctgcattt
    10801 cacggtagtg gggtaggaga gctgtcgcac tcgatccgac caccaataca gctaagagtt
    10861 gccccaccat catcaatgtc atcatccgtt tgagagggag tttccctttc aatagatcca
    10921 ccagactatt ttcctgtaaa ccaagtagat agacgacact tagtaaggta gaaatccctg
    10981 ccagggtcaa tccataaagt agaagagcaa tgatgaccag ttgcaccgtt gccataaaca
    11041 aggcaccttg ataccagaga atccccaatc ccaaaagact ggataccagc actgagcaga
    11101 taagctgtct cacatcttct aacactggtc tgagagcaac tccaaacaag ctctcaccag
    11161 ctattaagcg aatccctgcc tgacgaaggg atttgatccg ataaatcagg gtcagactca
    11221 taaaggtcag cagaaaaata gctaaactca gtagcaccat aggggtggcc gtcaatagta
    11281 agactatcga aaatggatct tctccattcg aaacaaagcc ttgataacca agctctttca
    11341 aggtggtctg taagctcact ccatccaaac ttcctgacac aatcaagtaa gaccctaata
    11401 aatcactcgt ttctgcactc tccttggagg aaatggtcag accttctgga agctttccct
    11461 caccataagt ggcataggta aagcgtgttt ctccagcttc atttggctca acaatccgac
    11521 gggcgatgag actattatgc tctaccgcca agtgactcaa agcctctgtc acctcttcgc
    11581 ggctagctac tggttgattt atcatcattc ctgtcacatc aacagaagga tagttaccaa
    11641 ataaaatctc ttctcgatgg tcaacggaag ttatcaccat ataaagcgat accaatacca
    11701 ttgaaatcaa aataaataaa cgtttcatca tttcctccaa aaagttactt ggtcacttag
    11761 tgagaaggtg accaagtaaa gctaaacaat agggctatac cattctaaac attatagtag
    11821 aatgcaactt tctctcccca agaagtacga atccatgcac gagaagtccc tccagcacca
    11881 gcatatccct tgtcagatga accagttttt ctgctaacaa ctgttgaact atggtatttt
    11941 gaagggtgat agtagtttga gtaagcacca ccgttacctg aaccataagt ccaaacacca
    12001 ccttctgggt attgaacggc tgcagaggca actgatacac ctccacctaa tgttgctgca
    12061 atgctcgcta caagagctaa ctttttaact gtttgtttca tattgatact cctctatttt
    12121 tgattacaag attgttgagt tacttgctcc tctttccatt atcaacgttg atactattat
    12181 attaccaaat gatattctaa aattatttgt ttttctctaa attgtcaaaa tagcaccctg
    12241 aaatgaactt ttatagtcat tatactccat ctttatcaca ctatcaagga catcaatgtc
    12301 cttaaaatct aactatttca tattattttt agcttatatc taaaaaaaca gttctaaaga
    12361 cgaactttag aactgttttg atacgaggac aaggacattt ttgtcactga ttcactatgt
    12421 ttataaatat tttttgacat cctcttgcca ttcctctgtc aatttcttta ctagaaattc
    12481 atctccaatt agcttcgcaa atgttttaga agactgataa aatgattcag ctaaactaaa
    12541 atctctttct actcttaatg cttgcttcca caaaaacata aatacaagag gtttcttttg
    12601 ataatcttga gttttatcca taatttcttg taaacacgat agataatcat taaaacaatc
    12661 agttactcct accttttcaa gacaacacat tcctgaaata agagtatctc taattataaa
    12721 gtaattctct atttgagtta ccttcttctg ttccaaaaga aagagcatta gcttttcgat
    12781 ttgatttata aatttggcaa gatcttttct aatgagcatt tgataaaaaa acaaacgaat
    12841 caacaacata tcatttattg aataagcttc tttttctata atctgaggca tatgttcctc
    12901 aagtattaac tctgcatatt caggccttct agttctagaa gtatccaaac acgcctgcaa
    12961 tacttcacat gctaattgtt cttctttagg aagattatca aagtatgttt tataaatctc
    13021 ttccaaacac gcttccttct tatcgtactc ctcttcttta ccatagattg gttcacgtaa
    13081 aatctggtat ttcaattcta aataagcaga aggaagagct gaaaaatccg gcataaggct
    13141 ataaactgga actcctagcc ggcgagcaat ataggctaac ttgggcaaac tcggttgcga
    13201 agctccactt tcaattcgcg acagttgacg aactgtcagt tcttgctcat ctccacaaaa
    13261 atctggacga ctaattcctt tttctatccg aatctcttta attttttgac caattaacat
    13321 cagacgcctc ctcttctacc tgcttcgaaa aatactgtga aacttaaaaa attgtaacgg
    13381 ctacatcttt cctactcata agatttcata gcttcttcca cttctgccaa agtaacccca
    13441 aacaactcta ggcgtttgag gagttgcttg ccgttagaat agccgattcg gagagtctct
    13501 ccgagatatt ctctacgctt acggctgtct gcccctgcta gaaaaccaag gcgaatcaag
    13561 tcgctacgac taatgtcaaa ctgactctca tgttcaaatt gttctgtcac ctgagctaga
    13621 gccgttttca ggtcttcata gctggcatgc tcaattccca gagaacgccc cttggtcttg
    13681 gacttgggaa cagcttcatc tcgcttgaga aaggcatgct gaactgttgg aatggccgtc
    13741 ataatcatgc gccgaatccg ctccccatta aaatctgggt ctgtaaagac aatgactcca
    13801 tgacgttggt gtagacgctg aatccgctct atgtcctggt cattgatggc agaacctcga
    13861 gtctcatagg tctccacatc gaaataacgc ttgagattga ccgtatcatc acgaccttca
    13921 accacgataa cttgggaaat tctctctttc attacttgct gtccaatcca aaaattcgtt
    13981 ctgcatttgc agtcgttgct accgccagct cttctgtcgt cataccacgc aagtcagcga
    14041 taaagtcgac cacatagcga gtataggctg ttttattttc acgaccacgc ttgggtacag
    14101 gtgctaagta aggcgcatct gtttccacca acatcttgtc caaaggtaac tctttagctg
    14161 cttcttggag gtcagttgcc ttcttgaaag tcaccactcc tgagaaggaa atggtcatac
    14221 caagatccac aaacttctct gcccactcaa gcgtccctga aaatgaatgc atgataccac
    14281 cacgaggacc aacgccctca ctcttgataa tctcataggt atcttccagc gcatcacggg
    14341 tatggacaac aaaaggcaaa tccaagtcct tagatagctg aatctgacgg cgaaaaacct
    14401 gctcctgcac ctctttgggc gctgtcatcc aatggtagtc taagccaatt tcacctaaag
    14461 ccacaacctt ggaatgtttt aacttatcca acaagtaagc ctcaacttcc tctgtataag
    14521 taccagcttc tgtaggatgc caaccaatag tcgcatagag ctgctcatac tcatctacca
    14581 acttcaaggc atgctcaatc gtcggtttat caaaaccaac aatattcatc tgtgtcacac
    14641 ccatctcatc agccaaggca atttcttctg cctcacgacc tgcaaattct tctacattca
    14701 agtgtgtatg tgtatcaaaa atcatctctt ctaacctcgt tttctatctt ctattatacc
    14761 aaaaaagagg aggggcacct aatttttcgg tttcccctcc tctcttcaat agagagctat
    14821 tctgctatct tttctatccg atattgccca tctcctgtcc cacagttaga gacagaagag
    14881 attggctaca ttgatagaat attcctattc agctaaagta tgtgattatc ttgggttctc
    14941 acttttctca cccatcacta ggattgataa cttctcaaaa tcccccttat aatctaactt
    15001 taagtagaga atagaatttt ctagctgttc tattttctac gtctagtctt tcttcctagc
    15061 aaagcaaaac cacttgttgc cgccgctaga ccaagactag caagtgctgc acttgatgct
    15121 gaacctgtgt taggtaattg tttgccagca ggtgactggt aggtaacatc ttgcattgtt
    15181 cctgcagttg cttgcggtgt acttgttgtc ttaggagcag cattaggagc cactggtctc
    15241 ttaggaactg taaccatggc aatggcttgc actccaatcg tttctgcttc cttcacatct
    15301 tccatagttt tcgtattttc aatctctttg agagctgctt gtttttctgc ttccactctt
    15361 gctaaaagtt ctgctttttc tttatcagaa agcggtgcgc ctttgatttc atcctgcttg
    15421 tccttggctg ctttttcaat ggcattttta gctgattctt tttcagtagc taattgctta
    15481 gaagcttgtg attgagctga gttttgtgaa cctgtgtgag ctgatccacc cgcctggcta
    15541 ccaccgcctt cattcgcatt agcatcttag cttccagtat tgcctccctt atctccacct
    15601 ggtgtatttt ctagcttata ctctggtgta gcttcttgag ttacagattc acctttcgca
    15661 gattgttgaa ctgtatcttt tcctagaatc gtcactactg aaccatctgg gaatgtgatt
    15721 gttgctgtac catctccagc tacattgatt gtcgctccgt ctaatgctga accatttgct
    15781 tgtaaaatag caaccttaac tttttcttca tctgttaaat gagttatatc ttttacatct
    15841 actctttgag caggtgcttt aacagttgat ttttcagcag tcagtttagt gctatcttgt
    15901 gcttttggat cttgtgctac caattgattt cctggaattg taatagctga accatcttta
    15961 aagacgattg ttgctgtacc atctccacct acttcaactt tatagtaaaa taaaataata
    16021 acaggacaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag aaacagaggt
    16081 gtactattct agtttcaatc tactgtaaca tcgcttccga atccatttgc atctactgaa
    16141 cttttttaca aaaataaaaa tcagtagact cgagttccta ctgatttttg atagaattcg
    16201 tttggattat gcagccaaaa ctttgcgtcc tttacgacga cgagctgcca atacgcgacg
    16261 accattttta gttgacatac ggttacggaa tccgtgtttg cgcgcacgac gaagtttact
    16321 tggttgataa gtacgtttca cgatgaatac ctcctcatag attttgtatt cgtttagccg
    16381 gctataaagt gatcagttac taaacatact ttactattct atctgattct ttcacttttg
    16441 tcaatagctc taggcaaatg tttccagctt tttcgaatgc aagccctatc tacgatactg
    16501 tttcaagaaa cgagtcatct tttcttggat ttgggctaac tcatcaacac gaggaaggta
    16561 aacgatacgg aagtggtctg gttcctgcca gttaaagcct cgaccatgaa ccaagagaac
    16621 cttttcctgc ttcaagaaat caaggacaaa ctgctcatca tcatcgatac ggtacatatt
    16681 gcggtcgatt tttgggaaga tatagagccc cgccttgggt ttaacggcag acaaacctgg
    16741 aatatcttga atggcattat agatgaaatt tctttgctcg tagattcgtc caccaggaag
    16801 aagcaattca tcgactgatt ggtgaccccc caaggaagtt tgtacgactt gttgggccaa
    16861 aacgttagag caaaggcgca tattggacag catattgagc ccttcgatat agcccttaac
    16921 atgagtctta gggccagaca agaccatcca acccacacgg aaacctgcta tgcggtggga
    16981 ttttgacaga ccattcatgc tgacacagaa gacatctggt gccaagctcg ccacaggcgt
    17041 atgcacatgt ccgtccatta ccatgcggtc atagatttca tccgcaaaga taatcaaatc
    17101 gttttgacgg gcaatctcaa taatctccag caagagttcc ttaggataaa gggctccagt
    17161 tgggttattt ggattgataa ggacaattgc cttggtattg gaagtgattt ttgacttgat
    17221 atcgtcaata tctgggtacc attccacagc ttcatcacag atatagtgaa cggcatttcc
    17281 tccagctagg ctgacagccg ccgtccatag aggatagtct ggcattggca ctaagacctc
    17341 atccccattg tccaaaagcc cctgcatgga catgacaatc aactcactga caccatttcc
    17401 aaggtaaata tcatcaatat ctacgtttgg gaatttcttc agctggcaat actgcatgat
    17461 ggccttacgg gctgagaaaa tccctttgga gtcagaatag ccttcactat cacgcgcatt
    17521 cataatcaag tcatgaatga cctcgtctgg cgctgtaaag ccaaattctg ctggatttcc
    17581 tgtattcaga cgtaaaatct tttctccatt cgctcgcatc cgcatggctt cttccaatac
    17641 aggaccacgg atatcataag caacatgctc taacttacta gacttgttat attctttcat
    17701 cttgtttcct caattcatca ggatagtaac attataccac tagaaagaga atgcgacaag
    17761 tttactgaaa tgtgttacta gtttcgtata gaagaaaaac cttgctaaag gcgaggttaa
    17821 gaacgtagag atagcaggta ttttgcaaag acacatcaca taccaaaaga taaacctaga
    17881 aaaaagcaag cctagaaagg agtcataaag aagattaaac atgaggaaaa gcccccatat
    17941 catcaagtaa tcccaacgcc cacttcgttt tgcaactaga aataagatta gatggtagag
    18001 tacatgaaaa actaaaaatc caataaaact tggataaaga agcggtacca gactctctaa
    18061 ttgacagatc atgatcactt ctaccaagac tgaaactagg ataattccat aataaaggaa
    18121 atttgatttt tgaaaagagt ttttcatcat tctcccttcc ttcacttctt tcctgctatc
    18181 ctttctttta ttttatcata tatttatata gagtttaagc cctaatattc ttttgaaaaa
    18241 tacttttttt gctttacttc tatagtgaaa aggtttacaa ttatagtaag aaaatttcag
    18301 gaggtttcat tatggcacaa cgttaccaaa atatcatggt cgcaatcgat ggttctaagg
    18361 aagcggactt ggcttttgtc aagggagttc attctgctct acgaaacgac gctaaactca
    18421 ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt atccaccttt gatgctgaag
    18481 tttacgaaga actccaagtc gacgctgaaa gtctgatgaa agagtacgaa aaacgtgcta
    18541 aagatgctgg ggtagcagat gttcatatcg tcattgaaat gggaaatcca aagaccctgc
    18601 tagcacgtac tattccagat gccgaggaag tggacctcat cctcgttggc gcaactggtc
    18661 tcaacgcctt tgaacgcctc ttggtcggct cttcatctga atacatactc cgccatgcta
    18721 aggtcgattt gctggttgtg agagaacaag aaaaaacctt ataatcacaa agaaaaggag
    18781 cccctagctc ctttttgttt acgatttatt tctctcttta tggcgttcgt aagccttgag
    18841 ctggcgctgc agttcctttt taatagcagg ttctggagca tatttttctt cccaattatc
    18901 tggttttaag attttatggg tcactggatc aaaatgagcc ttgccatctg gaaaaatttt
    18961 ccccatattg gcctgatgga caatatcaaa aatacgttct gggtccaccc ccatcaagac
    19021 aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca tccacttgcc ctatcaaatc
    19081 ttgctgagca ggtgtcttct tggctacttt atctgctgcc ttatcaaggg cctgatgaag
    19141 ttgcgataca gcttgaccaa aatcttcttc agaaggactg gctgctcgaa caaactccac
    19201 caattcttct attttaaaac cagccctatg ggttgcaccc tctaaatccc aagctcgagg
    19261 ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc ttgaccttat tgaaatgata
    19321 gtcacggctg acaaagactt tttctgaaga caaaacacca aaatgttcca aggccttgtg
    19381 gattccatct tgttgattgc tagtggtaat gtgcttggca gcttccttga cactgctact
    19441 accatttccc atagcgaccg acataccaac gccagccagc atttcaagat cattatctga
    19501 gtcaccaaaa gccatgactt ggttgaggtc aaagccatat tctttcccaa ctcggcgaat
    19561 gccttctaat ttagaatttc cctgattgat gacatccgat gcaaaaggat tgctacgtgt
    19621 caatttcaag tcttcaaaat cagctgccgc cttctcagat tcttctggtg tcatcagcat
    19681 caaaacttgg tagataggct gattcatcag gtgaagcagg tcctcttcct tttggggaac
    19741 aaccttgctg accatgcgat taaaagactg actcaccgtc cgagttaaaa cagagggaac
    19801 gaagcgacta attcgttggg aaaaagaacc cagaccaaag gacatgattt tagaacccaa
    19861 catggcatcc ttggtcccta gagcaatctc cgtgccctct tttttagcat agctaattag
    19921 atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag actctgtctt tactaaagat
    19981 atactggcca ttataggtta ccgcaaaatc cagatccaaa tcgtccatca attccttaac
    20041 aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc ccttgttctt tgacaatctt
    20101 aatcgcatcc ttagtggatt tcaaaacact cttgcgattg ttgaccaagg ttccatcgat
    20161 atcaaaaaaa acagctttga cttccatcct atcccaatct ccccttttgt gatacaatga
    20221 ttataccaca tttcagaaag agtgagtaaa tcatgcctaa gaaaatcctt gttttacata
    20281 cgggtggaac tatttccatg caggccgatg cttctggcgc tgttgtgacg agttcagata
    20341 atcccatgaa ccatgtgtcc aacccacttg aaggaatcca agtccacgcc ttggactttt
    20401 ttaaccttcc aagtccctat atcaaaccca aacatatgct ggtcctctac cagaaaatta
    20461 aagaggaagc agataactac gatggagtgg tgatcacaca cggaaccgat actttagagg
    20521 aaacagccta tttccttgat accatggaag ttccccatat gcctatcgtt ctaacaggag
    20581 ccatgcgtag ctccaatgag ctcggtagtg atggtgttta taattaccta agtgctttac
    20641 gagtggccag cgatgacagg gctgctgaca aaggagtttt ggtcgttatg aacgatgaaa
    20701 tccacgctgc caagtatgtc accaaaacac atacgactaa tgtcagcacc ttccagactc
    20761 caacacatgg cccccttggt ctcatcatga aacaggaaat cctctacttc aaaacagctg
    20821 aacctcgtgt tcgctttgac cttgatcaca tacaaggttt agtccctatc atctcggctt
    20881 atgctggtat gacagatgag ctgattgata tgctggattt agaacacttg gacggtttga
    20941 ttatccaagc cttcggagct ggtaatattc ccaaagaaac ggctcaaaaa ttagaaagcc
    21001 ttctgcaaaa aggaattcca gtcgctctgg tatcacgatg ctttaacggt attgccgagc
    21061 ctgtttatgc ataccagggt gggggcgtac agttgcaaaa agcaggcgtt ttctttgtta
    21121 aagaactcaa cgcccaaaaa gctcgcttga aactcctcat cgccctcaat gccggactaa
    21181 caggacaggc tttgaaagac tatatggaag gctaatactc ttcgaaaatc tctgcaaacc
    21241 acgtcacgtc gccttaccgt atgtatggtt actgacttcg tcagtttcat ctacaacctc
    21301 aaaaacatgt tttgagctga cttcgtcagt tctatctaca acctcaaaaa catgttttga
    21361 gctgacttcg ttagtttcat ctacaacctc aaaaacatgt tttgagctga cttcgttagt
    21421 ttcatctaca acctcaaaaa catgttttga gctgacttcg tcagttctat ctgcaacctc
    21481 aaagcagtgc tttgagctga cttcgtcagt tctatctaca acctcaaaac agtgtgttgc
    21541 gcagccttta atcagccgcc tagtccgctc tatggtattc attaagtcaa catctcttgt
    21601 ttaagagcac caaatcagga aatcttctcg attccctgat tttttctatt tacgttttcg
    21661 tgttgagcta cgttctgtca aaccatgagg taagagaact tcacgttctt ccaactcttc
    21721 cttatgcata atcttggtca acatacgcat actaatggca ccaaggtcat aaagaggttg
    21781 ggcaatcgtt gtcaagtttg gacgggtaaa gcgtgagatt tgtgaatcat cactagtaat
    21841 aatttcaaaa tcttctggca cagaaacacc cttatcagcc aaaccgttca agactcctgc
    21901 tgccaactca tcacctgtca caactgctgc agttgcattt gatgaaatca aacgctctgc
    21961 taaggcgtaa ccatcatcat agctatattt agattcaaat accaaaccct cactataagt
    22021 gattcctgct tttttcaagg tttccttgta gccaactaaa cgaaccttac cattgatgtc
    22081 atccactagc ggaccgctaa cgaaagcaat acgctcattt tctttagcaa ggtaactcac
    22141 tgcatcaatt gttgcttgct tatagtcaat attgacactt ggcaactggt gctcaacatc
    22201 gacagttcct gcgagaacaa tcggagtacg tgaacgcgaa aattctgagc gaattttatc
    22261 tgtcaagtga taccccatat agataatgcc atctacctgc tttgaaaaga gggtattgac
    22321 aacagaaact tctttctcgt tatcttcatc gctattagct aggacaatat tgtacttgta
    22381 catttctgca atatcatcaa tccccttagc caaactcgaa aaataaccat tggtaatatt
    22441 tggaatcacg acaccgacag tggttgtctt tttacttgca agaccacgcg caactgcatt
    22501 tggacgataa tccaaacgat caattacctc tagcactttt ttacgggtat tctcttttac
    22561 atttttattg ccattgacca cacggctgac cgtcgccatg gaaacacctg cttcacgagc
    22621 gacatcataa atggttactg tatcatctgc attcattcct tttcctgtcc tttctatctc
    22681 acacattctt ttacaagtag aggtactgat tgaagctcta tatctactta caaaagtgaa
    22741 gatgtgaaaa tttcgttttc atatttctac ttattccatt ctatcactaa ttgtaaacac
    22801 tttcaagtgt tttttgaaga ttgattgaaa aaatttcata gaaaacctag gtttagctcc
    22861 ttgctaccac cttagactaa acaaaaagga ggaaactaag ccctcctaaa gttatagtaa
    22921 aatgaaataa gaacaggata aatcgatcag gacagtcaaa tcgatttcta acaatgtttt
    22981 agaagtagag gtgtactatt ctagtttcaa tctactatag gtattgttcc attcactacc
    23041 gtcaatttta gcacatagtc ttcatgaaaa tattatatca tcataaccaa ccagattctt
    23101 tcgcgatatt agctgcctct gttcgattac ctgcatctag tttcgaaaga atattggtga
    23161 catagtttcg gactgttccg ttggatagat aaagtttgtc tgcaatttct tggttagaga
    23221 agccctgagc aattcccttt aaaactgcga tttcttgctc cgttaatgga ttgggatgca
    23281 tcatcaccac ttccatcaat tcaggcgaat actccttgcg tccttcgagg acggtgtgca
    23341 aggtttgcat gaggtctgca atgtttcttt cttttaatac ataagcatct actccagcct
    23401 tgaccgcacg ttcaaaatac ccaggacgct tgaaggtcgt caccacaacc acctttgttt
    23461 caagcttttc tgctcgtatc cactccaaga cttcaagacc tgtcttaaca ggcatttcta
    23521 cgtcaaggat ggcgatatct acagactcct tttctaatag ttggattgct tcttgcccat
    23581 tcttggcttg aaagacagac tctacatccg gttgaagcat gagcaactgg cacatggcat
    23641 ctcgcaacat actttgatct tctgcgacta atactttcat ctactttctc tccttataaa
    23701 gtagtcgaac ctgcacttca gttggatgtt tctgactgat tacacttact tctcctgaaa
    23761 atggaaaaac acgatttcgg actgtatgga gctcatcccc gcttatagag gcaaagccac
    23821 agccatcatc tctcactgtt agaatgagtt ctttctctgt ccgttctaat ttcaagtaga
    23881 ctttagacgc tttagcatgt ttgatgatat tggtcactaa ttcaagcaaa atcatggaag
    23941 ccgttgactc caattcctga gttaagctag acttgtccaa gtgattctca acttgaacct
    24001 caattccagc aatttctaac atctttttca cagtctctag ttcggatgtc aaagttctag
    24061 acttaagatt ttccacaatg gttcgcactt cattcatgga atccttgctg atctggtgaa
    24121 tttcttttaa ttccttttcc acctgtggat aagcctccat ctgaaataac tgcaaggcta
    24181 aatctgtctt gacactcagc atagcaaagg tatgtcccag actatcatgc aaatcctgac
    24241 cgatacgact acgttcattt tcagcaagca atagatttat ctgagcattt tgcttgacct
    24301 gagcttcttt caaatcctcg acaatacgaa tccgaaccaa tccaaaagtc attaaatcga
    24361 caaaagtaag aattacaagt agatagaata gaaactcaac ttcgattctc tgaaaaatca
    24421 acagttgccc cacaacaagg acttgagcaa gaagaaaagt ccagacatgt aaagacttta
    24481 aactacgtac gctgaaatga taacttaaga gattggatag gaaaaagaaa aaccagatat
    24541 aattaacagc aacaaaggca gtattcccaa ctacataagt cagcatgagg ccccaatata
    24601 gccaagatag gcgctggctc ttagttgtta aaacacccaa atatgccact acaaatagaa
    24661 tatcaatcaa taaatgccag gcagaaagcc acccagtcac tacagacagg atggggaaaa
    24721 tcataaaaat taaactgatc caaaacatat aatgtattct tttcagtctt tcaagcatta
    24781 agcattctcc ttatgacctt gaaggtaaat agtcaaacca aataaaactg ctgaaaaaac
    24841 aagtagataa actgtggctg atagattgat tccaccctca tttaagaagg tcttgattaa
    24901 ttccatcaac tgataacttg gtaaacgctt cccgattgct tgcatccagt ctggaaataa
    24961 agagacgggc atccagagtc cgcctaaaac agccaatcct agataaagaa gattgcccac
    25021 gacagacatc agctgactag ttggtaacag cgtcaaggtt aagccaagtg ctacaaaagc
    25081 aatacttccc aaaatcagca aaatcgcagc tccaacccat tttactagag gcatgtctac
    25141 acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt gagaccaaat aatcaaccag
    25201 catacttgtt atctttgata gataatattc taccatattt actgggctat gacgtaatat
    25261 tttctgccag ttgttcatct tgtcggtatg taagacagct gggaatgaaa agatagcggt
    25321 cgacatcatg gaaaagccag tcatggagat gaggtaatca cgcataaaat tcgcgggtcc
    25381 acctggtgtg tcctggtaca tgccagaaaa gaatagatag aaggctgtcg gcatccctac
    25441 tgacaataga taatagatca attgtcgttt ggtcaataaa aattctatct tactaagtgc
    25501 tagccatcgt ttcatcttag ttatctccct tctgcgtttc ttcaaagatt gtatccaaca
    25561 aactacgatt attaacttca atttcttgta tgccacatcc tgcttgaact aacagttccc
    25621 aaaaagcatc tgcttcgcgt gtgactactt gtagagcatc ctgtttttgt gaccagtttt
    25681 caaccaagtt agactgctca atgacttcct tgtatgccag aggaaggata aaatgctttt
    25741 caattccctc actacgcata gctagaggcg tcgtatcacg aatcaactct cccttattta
    25801 agagcaaaat gcggtctgca gtgtgttcca cttcctcaat ataatgggac gaatagagaa
    25861 tggtgactcc ttgcgctttt aactcctgga caatttccca aaaacgttga cgagttgagg
    25921 tatccatgga cgcagtaggc tcatctaaaa aaacaatctt tggtcgccca attaaggtca
    25981 agacgaaaga aaagagacgc ttttgaccgc ctgataattt ttctgccaac tgttcttttt
    26041 gttgcttgac aaactgcaat agttgatcaa cttcctgatt gctcaaagga tttggataga
    26101 tacgttgaaa gaaagcaatc aactctttaa cttttaattt ctgaacgatt acattttctt
    26161 gagggaggta agccctagta tagtctaact tagaactcgt cactggtaaa ccttgaatag
    26221 atacttgacc gcttgtgacc agtttatctc caagcaaaca atctaagagt gttgtctttc
    26281 cggcaccatt tggaccaatt aaggcaacac attcaccatc gttgatttca aaggagatgt
    26341 tccgcaaaat ttccttgtct tttattttct tactcaattt ttcaacttta accacagtca
    26401 tgagactctc ctttcaacca ctccattccc atagggaaaa cgacgaaaat cataaatcca
    26461 aaccccaaag caccacgaat gaattggcga agcaaggctt gatcaaacca atcagtaaac
    26521 atttccacta accataccaa gagtgacagg ccgataaaga aatagatgat ccctttcttc
    26581 attcctcaaa ctcctttttc acatctctga ctaatttcaa accttctcta acaagccaag
    26641 acatgattcc aaagccagca aagatctttc aaggaaaatg gtagaaatcc tcatccaatc
    26701 ccgaaaacat gagataggtc ataactcctg ctactactaa acttactgcg ataatcattt
    26761 tatttctcat ctcttcttcc cccatttcat actacaatta tagtctttta aaatcagagg
    26821 aggcagaagc ttctgtcact agaaaatatg acaaatgtca taaaaaattc tgttcaaaac
    26881 aagcaagata cactatacaa taaaacacaa ttagaaaaat ctaaggcaac ttcctcaaaa
    26941 gagatatcaa acccaattca caccataatg taaactaata cttatttaaa atcaaaaaga
    27001 gtagaaattt ttatcagaca aacacatata tagtgtattg aatctataac agtaggcctt
    27061 aaatactaac atatttctat aaattaattt aactttcctg atagagctgt tcatatctta
    27121 tttcaattct ctaaattata cgttgaacaa aacccttcta tttctttctt aaagatttat
    27181 aagagttata aaatctgtta aatttcaatg tgtataccta aactacggta tttattgaaa
    27241 agactggaga caaaaagtat acgctgccaa aatgaattac tgaaaatcaa aaaagagaga
    27301 accaaactga ttccctctta atgtatataa tatctagttt taaaaataca cactcacata
    27361 tctctgt
//
LOCUS       DBEJZV010000025        24905 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.25, whole genome shotgun sequence.
ACCESSION   DBEJZV010000025 DBEJZV010000000
VERSION     DBEJZV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24905
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.25"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..762
                     /locus_tag="ACL3S0_001447"
                     /pseudo
     CDS             1..762
                     /locus_tag="ACL3S0_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638988.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(972..3230)
                     /locus_tag="ACL3S0_001448"
     CDS             complement(972..3230)
                     /locus_tag="ACL3S0_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR1312343.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKVLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
     gene            complement(3459..3689)
                     /locus_tag="ACL3S0_001449"
     CDS             complement(3459..3689)
                     /locus_tag="ACL3S0_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGR1312344.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3879..4562
                     /locus_tag="ACL3S0_001450"
     CDS             3879..4562
                     /locus_tag="ACL3S0_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1312345.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4562..5296
                     /locus_tag="ACL3S0_001451"
     CDS             4562..5296
                     /locus_tag="ACL3S0_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR1312346.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5450..6307
                     /locus_tag="ACL3S0_001452"
     CDS             5450..6307
                     /locus_tag="ACL3S0_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGR1312347.1"
                     /translation="MTQIIDGKALAVKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            6449..7321
                     /locus_tag="ACL3S0_001453"
     CDS             6449..7321
                     /locus_tag="ACL3S0_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGR1312348.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7603..8286
                     /gene="rpiA"
                     /locus_tag="ACL3S0_001454"
     CDS             7603..8286
                     /gene="rpiA"
                     /locus_tag="ACL3S0_001454"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGR1312349.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            8300..9511
                     /locus_tag="ACL3S0_001455"
     CDS             8300..9511
                     /locus_tag="ACL3S0_001455"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGR1312350.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9513..10070
                     /locus_tag="ACL3S0_001456"
                     /pseudo
     CDS             9513..10070
                     /locus_tag="ACL3S0_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893195.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            10070..10879
                     /locus_tag="ACL3S0_001457"
     CDS             10070..10879
                     /locus_tag="ACL3S0_001457"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR1312351.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            11355..11751
                     /locus_tag="ACL3S0_001458"
                     /pseudo
     CDS             11355..11751
                     /locus_tag="ACL3S0_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
     gene            12064..12339
                     /locus_tag="ACL3S0_001459"
     CDS             12064..12339
                     /locus_tag="ACL3S0_001459"
                     /inference="COORDINATES: protein motif:HMM:NF012956.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGR1312352.1"
                     /translation="MENIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQ
                     SKPWWQVDLAKEETIRQINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            12364..12877
                     /locus_tag="ACL3S0_001460"
                     /pseudo
     CDS             12364..12877
                     /locus_tag="ACL3S0_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
     gene            13531..14241
                     /gene="deoD"
                     /locus_tag="ACL3S0_001461"
     CDS             13531..14241
                     /gene="deoD"
                     /locus_tag="ACL3S0_001461"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR1312353.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKFGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(14264..14788)
                     /locus_tag="ACL3S0_001462"
     CDS             complement(14264..14788)
                     /locus_tag="ACL3S0_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGR1312354.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14841..15077)
                     /gene="rpsT"
                     /locus_tag="ACL3S0_001463"
     CDS             complement(14841..15077)
                     /gene="rpsT"
                     /locus_tag="ACL3S0_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGR1312355.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(15145..16065)
                     /gene="coaA"
                     /locus_tag="ACL3S0_001464"
     CDS             complement(15145..16065)
                     /gene="coaA"
                     /locus_tag="ACL3S0_001464"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGR1312356.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            16263..16667
                     /locus_tag="ACL3S0_001465"
     CDS             16263..16667
                     /locus_tag="ACL3S0_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312357.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFSIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16874..17464
                     /locus_tag="ACL3S0_001466"
     CDS             16874..17464
                     /locus_tag="ACL3S0_001466"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR1312358.1"
                     /translation="MSKMYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDF
                     GSQLLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEK
                     NNAKATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            17461..18738
                     /locus_tag="ACL3S0_001467"
     CDS             17461..18738
                     /locus_tag="ACL3S0_001467"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGR1312359.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLEDGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18756..19418
                     /gene="deoC"
                     /locus_tag="ACL3S0_001468"
     CDS             18756..19418
                     /gene="deoC"
                     /locus_tag="ACL3S0_001468"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGR1312360.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            19405..19794
                     /locus_tag="ACL3S0_001469"
     CDS             19405..19794
                     /locus_tag="ACL3S0_001469"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR1312361.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19885..20937
                     /locus_tag="ACL3S0_001470"
     CDS             19885..20937
                     /locus_tag="ACL3S0_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGR1312362.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            21081..22616
                     /locus_tag="ACL3S0_001471"
     CDS             21081..22616
                     /locus_tag="ACL3S0_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312363.1"
                     /translation="MAHENVIEMRDITKVFGGFIANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIHRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22609..23667
                     /locus_tag="ACL3S0_001472"
     CDS             22609..23667
                     /locus_tag="ACL3S0_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312364.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23670..24626
                     /locus_tag="ACL3S0_001473"
     CDS             23670..24626
                     /locus_tag="ACL3S0_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312365.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            24711..>24905
                     /locus_tag="ACL3S0_001474"
     CDS             24711..>24905
                     /locus_tag="ACL3S0_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR1312366.1"
                     /translation="MKLSYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQE"
BASE COUNT         7314 a         4467 c         5603 g         7521 t
ORIGIN      
        1 gatagactta aaaactatct tactgacaat ccagacgctt atttgactga aatagcttct
       61 gaatttggct gtcatccaac taccatccac tatgcgctca aagcgatggg ctacactcga
      121 aaaaaagaac cacacctact atgaacaaga cccagaaaag tagccttatt tcttaagaat
      181 tttaatagtt taaagcacct agcacctgtt tagattgatg aaacaggatt cgatacttat
      241 ttttatcgag aatatggtcg ctcattaaaa ggtcagttaa gaagaggcaa agtatctgga
      301 agaagatatc agagaatttc tttggttgca ggtctaacaa atggtgagtt aatcgctcca
      361 ataacttacg aagagacgat gacgagcgac ttttttgaag cttggtttca gaaatttctc
      421 ttaccaacat taaacacacc atcggttatt atagtaaaat aaaataagaa taggataaat
      481 cgatcaggac agtaaaatcg aattctaaca atgttttaga agtagatgtg tactattcta
      541 gtttcaatct actatattat ggataatgca agattccata gaatggggaa gctagaactt
      601 ttatgcggag agtttgggca taaactttta cctcttcctc cctactcacc tgagtacaat
      661 cctattgaga aaacatgggc tcatatcaaa aagcacctca aaaaggtatt accaagttgc
      721 aatacctttt acgaggctct tttgtcctgt tcttgtttca attgactgta gcagattgaa
      781 ataagatgag aacaaatcga tttggaaagt aaaattaatt tctataaatg ttttagcaat
      841 tgtttcgtac tatttcagat tcagtctact atatatcata atggacaaag ggcaagctgt
      901 caagaaatta cagttatttt agtaaaaaaa gaagcagaaa aatttcattt tctactcctt
      961 ttctatagga tttatttttc tttttcagaa cttttaactt cagttttttt ggcagattta
     1021 atctgaatgt ttcccttgct agtcataact gctttgagaa ctttttcgct tggattttca
     1081 aggtagtagt cagtgattgt gtcctcaata tagtcttgaa tagttcgacg aagtgggcgt
     1141 gctcccattt ttggatcata acctaggtca accaactttt ccttgacctt gtcagttaca
     1201 tccaaacgaa tgttgttgct agagaggcgc ttgttaacat ctgctagcat gagctcgaca
     1261 atctgaagga ggttatcctt gctgagagcc ttaaattcga taatgccatc aaaacggttc
     1321 ataaactctg ggctaaagaa gttaccgagt tcaccgagga cagaattggt acgtccttct
     1381 ctagcagcac caaatccaac gctagcttcg gtctttcctg tacctgcatt tgaggtcatg
     1441 ataatgatgg catccttgaa gctaacggtg cgtccttgcc cgtctgtcaa acgaccatcg
     1501 tccaagactt gaagaaacat gtgcataaca tctgggtgag ctttttccac ttcatcgaga
     1561 aggatgagag aatatggatt gtggcgaact ttttcagtta attgaccagc ctcatcatag
     1621 ccaacataac ctggaggagc gccgaccaac ttagccacac tatgtttttc catgtattca
     1681 ctcatatcaa agcgaatcat actatcagca gaaccaaaaa gttcgatagc cagttgtttg
     1741 gaaagttctg tcttaccgac accagttggc ccaacgaaga ggaagcttcc gattgggcgg
     1801 ttaggggtac caagtccgac acgattacgg cgaatagcct tggcaatctt atcgactgca
     1861 tcatcttgac caataacatg agacttgaga tcttcggcta gatggatgag ttgagattgt
     1921 tctttctctt tcaaatcacc aacagggata ttggttttct gctcgataat gtgctcaata
     1981 gttttctcgc tgatgatagg agtatcctgg tctgtgatct ttttcttttg catttcctta
     2041 tacttggcaa tctggtcgcg gaagtaggcc gccttctcaa aatcttcttc tcgtgtagct
     2101 tgagacttga gattttcagc ctcaatcaag cgctgatcaa ttactttagg atccacaaaa
     2161 ttcaaggtca agttcatctt agaaccagct tcatctagga ggtcaatggc cttgtcaggc
     2221 aagaagcgat cttggatgta gcgattggaa agagttgcag ctgcttcaat cgcagcatct
     2281 gtatattgaa cgtggtggta atcttcgtat ttcttttgaa tccctttgag aatagtgatt
     2341 gtttcgtcca ccgttggttc atcgacttta acaggctgca tacgacgctc gagggcagca
     2401 tccttttcaa tgatacggta ttcattgagg gtagtagcac cgactagttg cagttctcca
     2461 cgagcaaggg ctggcttgag gatatttcct gcgtccatat taccatcact cgcagaacca
     2521 gcaccaacaa tttcatggat ttcatcgata aagaggatga tgtcttcacg tttgcgaatt
     2581 tcttccatga gtttttgcat gcgttcttca aattgtcctc gaatccccgt tccttgaact
     2641 aagctaacca catccagacg gatgacttgt ttaccttgga gtttatgtgg cacatcgcca
     2701 tcgacaattt tctgagctag accttcgaca acggccgttt ttccgacacc aggttcaccg
     2761 ataaggacag gattattctt ggttctacga ttgagaatct cgatgacacg gataatctca
     2821 tcgtcgcgcc caataacggg gtcaatgtct ccacgacggg caatttcagt tacattaata
     2881 ccaaattctt ccagcaggcc tttttcttgg ctaggtggcg gagtttgagc agatccacga
     2941 ttttgggaac cataaccgcc gtttccaccg taacctccac ctgattgggt tgggggaata
     3001 ggaggagtat tgctagaagg tctgaaattg tttagatcat tgaagaaatc accaaaggga
     3061 tcgaagtcac gattgttcag atccgtcata cctttgaaga ggctattgtt aggatctgtt
     3121 ttgataatct tatagcagtt ttgacagagg tcaatttgtt tttgttttcc attgagattg
     3181 gtgtaaagat gaattgttga gtcgttaatt ttacagtttt gacaaagcat acatctacct
     3241 catttctttc tttagcctga cttgtttaaa ggtcaaaaat agtcaaattc tatactctca
     3301 ttataacagg attggggtgt aaagcaagta aaaagattga agctttgaga agttgttaca
     3361 atgaaaattt ttgtgaattt ggactataaa aaaatcctat ttgtgagaca aaaaggattt
     3421 tacttagaca tgcagggaca atcccagctt gttttagatt agtagagaag ttcgtaaatt
     3481 tccattgcga ttaagtcaat gctatcaaac gtatacgttt cgcgatcttc tacgtcacga
     3541 agggtaaaga ttgggccgtt ttcttcgtcg tggctgtacg caacttctgc aacaacaact
     3601 ccttcgcgtt caaaattacg ttttaaattt ccgccatcgt ttgccattgc ttcaaggcgg
     3661 ttgatgattc taaccaaatg tgattccatt ttgattctcc ttcatttctt atcgttacta
     3721 ttttaccata aaggaggcca acttgactag aaaaaactaa gatttctcac taattctgct
     3781 agtttaaaga tttttaaata aattggataa aagatttaaa ttttaattca aaacatgtta
     3841 taatcataca gtattctatt ttagaaagca gtgtgactat gaatttttct tttttaccta
     3901 agtatttacc ttattttaac tatggggctg ttgtgacgat tcttatttct atctgtgtta
     3961 tctttttggg aactattttg ggtgttgtct tggcttttgg gcaacgttca aagtttaaac
     4021 cgcttgtttg gttggccaac ttgtacgttt ggattttccg tgggacaccg atgatggttc
     4081 aaattatgat tgcctttgct cttatgcata tcaatgctcc gactattcag attggaattt
     4141 taggtgttga tttttcgcgt ctgattccag ggattttgat tatctctatg aatagtggtg
     4201 cttatgtttc ggagactgtt cgtgccggaa tcaatgcggt tccaaaaggt cagctagagg
     4261 cggcttattc gctagggatt cgtcctaaaa atgcgatgcg ttatgtgatt ttgccacaag
     4321 caatcaaaaa tatcttgcca gcattgggga acgaatttat caccattatc aaggacagct
     4381 ccctcttatc agctattggg gtcatggagt tgtggaatgg ggctacaaca gtttctacaa
     4441 caacctatct acctttaaca ccacttttat ttgcagcatt ttactacttg attatgacct
     4501 ctattctgac agtagccttg aaagcttttg aaaaacatat gggacaagga gataagaaat
     4561 aatgacagaa accttgataa aaattgaaaa tttacataaa tcttttggaa agaatgaagt
     4621 attgaaggga atcaacctcg agattaaaag aggagaagtt gtcgttatca tcggtccttc
     4681 agggagtggg aaatctacct tgcttcgctc tatgaatttg ttggaggaag caaccaaggg
     4741 gaagcttatc tttgagggag tcgatattac ggacaagaag aatgacttgt ttgccatgcg
     4801 tgagaagatg ggcatggttt tccaacaatt taacctcttt cctaatatga ctgtgatgga
     4861 aaatattacc ttgtcaccta tcaagactaa aggtgaaagc agggaagttg ctgagaagag
     4921 agcccaagag cttttggaaa aagttggttt gccagataag gcagacgctt atccacagag
     4981 tctgtcgggt gggcaacaac aacggattgc catcgcgcgt gggttggcta tggaaccaga
     5041 tgttttgctc tttgacgaac caacttcagc cttggatcct gaaatggtag gtgaggtatt
     5101 ggctgttatg caagaccttg ccaagtcagg gatgactatg gttatcgtaa cacatgagat
     5161 gggatttgcc cgtgaggtgg cagatcgtgt tatctttatg gcagacggtg tggttgttga
     5221 agatgggaca cctgagcaga tttttgaaca aacccaagaa caacggacta aagatttctt
     5281 gagtaaggtt ttataatcta ttttaaaatt tcaagacaag attagtgaaa agttcaacca
     5341 gagctttttc ttatagtttg aaactatagg ataacctagg aaagaagtgt tagagggcac
     5401 tagcagtttt tggtataatg gaagatattt gaaagaaaag agaagtgata tgacacagat
     5461 tattgatggg aaagctttag cggtcaaatt gcaggggcag ttggctgaaa agactgcaaa
     5521 attaaaggaa gaaacagctc tagtgcctgg tttggtagtg attttggttg gggataatcc
     5581 agccagccaa gtctacgttc gcaacaagga gaggtcagct cttgcggctg gttcccgtag
     5641 cgaagtagtg cgagttccag agaccattac tcaagaggaa ttgttagacc tgattgctaa
     5701 atataatcag gatccagctt ggcatgggat tttggtccag ttgccattac caaaacatat
     5761 cgatgaagag gcggttttat tagccattga cccagaaaag gatgtggatg gtttccatcc
     5821 cttaaacatg ggacgtcttt ggtctggaca tccagtcatg attccctcga cacctgcagg
     5881 aattatggaa atgtttcatg aatatgggat tgacttggaa ggtaaaaatg cggtcgtcat
     5941 cggtcgttca aatatcgttg gaaaacctat ggctcagctt cttttggcta aaaatgcgac
     6001 agtaaccttg acccactcac gaactcataa tcttgccaag gtggctgcta aagcagatat
     6061 tcttgtagtc gcaatcggcc gcgccaagtt tgtgactgct gactttgtca aaccaggtgc
     6121 ggttgtcatt gacgttggga tgaaccgaga tgaaaatggg aagctctgtg gagatgttga
     6181 ttatgaggca gttgcaccac ttgctagcta tatcacgcca gtccctggag gtgtcggtcc
     6241 tatgaccatt accatgctga tggagcaaac ttatcaagca gcacttcgga cattggatag
     6301 aaaataagag aaacattcga ttaatagagt gtattttcta tagctatatc taaaatggca
     6361 gaaatgaata ttaaatttta gatataagat tacaaaagga ggtctgcgtc tcctttttat
     6421 tgtataataa aagtgagagg aaaaaaggat gaaagtgatt aatcaaacct tattagaaaa
     6481 agttattatt gaacgttctc gttcaagtca taaaggagat tatggtcgtc tgctgctgct
     6541 tggtggtact tatccttatg gaggtgccat catcatggct gctttagcag ctgtaaaaag
     6601 cggtgcagga ttggtgaccg ttggaacgga cagggaaaat atcccggctc tgcacagcca
     6661 tttacctgag cctatggcct tttctcttca agaccagcaa ttgttaaaag agcaattgga
     6721 gaaggcagaa gttgtcttgt tggggcctgg tttacgagac gatgcttctg gagaaaatct
     6781 agtaaaacag gtctttgtta atttaagcca aaatcagatt ttgattgtag acggaggtgc
     6841 cttgaccatt cttgctagga caagtttgtc atttccctca agccagctta tcctaactcc
     6901 tcaccaaaaa gaatgggaaa aattatctgg aattacgatt gaaaagcaaa aggaagatgc
     6961 aacggctagt gttctgactt ccttccctca aggaacaatt ttggtggaga aaggcccagc
     7021 tactcgtatt tgggaagttg gccaatctga ttattaccag ttacaggttg gtggtcctta
     7081 tcaggcgact gggggaatgg gagatactct ggctgggatg atcgcaggat ttgtaggcca
     7141 attccgacag gccagtctct acgagcgtgt ggcagtagcg acccatcttc attcagccat
     7201 agcccaagaa ctatctcaag aaaattatgt ggtcttaccg acggaaatca gcaggtatct
     7261 tcccaaaata atgaaaatta tttgtcaaca agagagggta agcaaagata aacttgttta
     7321 aaatagacag ataaatctac ttccttctct taatttatga ttcttgaaat gcgcctgctt
     7381 taaggctaaa ctagacgtat caaagttaag agtttgtttt tgtaactgga aagagatgaa
     7441 caaatcaaat acataaaaga taaactcatt tttattcgtt tggtaaaaat aaaatgcata
     7501 tttttaaaga aagattgatg aaaaatgtag atttgatgtt tttacttgaa taaaaagcgg
     7561 tttcatagta aaataagaac tgagaatgat ggaggtaaat cggtggaaaa tctgaagaaa
     7621 atggcaggta tcaaggctgc tgagttcgtg agcgatggaa tggtcgttgg acttggaaca
     7681 ggctcgactg cctattattt tgtcgaagaa atcggtcgtc gtatcaagga agaaggattg
     7741 cagattacag ctgtaacaac ttctagtgtg accactaaac aggcagaagg ccttaatatc
     7801 ccgctcaagt ctattgacca agtagacttt gtcgatgtga cggttgatgg cgcggatgaa
     7861 gtggatagtc agtttaatgg aatcaaaggc ggtggtggtg cccttctcat ggaaaaggtg
     7921 gtcgcaacac catcaaaaga atacatttgg gtggtggatg aaagcaagct ggtcgaaaaa
     7981 ctaggtgctt ttaaattgcc agtagaagtg gttcagtatg gtgcagagca ggtctttcgt
     8041 cattttgaac gagctggcta caaaccaagt ttccgtgaaa aagacggcca acgttttgtg
     8101 acggatatgc agaattttat cattgacctc gccttggatg tcattgaaaa tccaattgct
     8161 tttggacaag aattggacca tgtcgttggt gttgtggagc atggtttatt caaccaaatg
     8221 gtggataagg taatcgttgc tggacgagat ggagttcaga tttcaacttc aaaaaaagga
     8281 aaatagaagg gggcataaga tgtctaaatt taatcgtatt catttggtgg tactggattc
     8341 tgtaggaatc ggtgcagcac cagatgctaa taactttgtc aatgcagggg ttccagatgg
     8401 agcttctgac acactgggac acatttcaaa aacagttggt ttgaatgtcc caaacatggc
     8461 taaaataggt cttggaaata ttcctcgtga aactcctctt aagactgtag cagctgaaat
     8521 caatccaact ggatatgcaa caaaattaga ggaagtatct cttggtaagg atactatgac
     8581 tggacactgg gaaatcatgg gactcaacat tactgagcct ttcgatactt tctggaacgg
     8641 attcccagaa gaaatcctga caaaaatcga agaattctca ggacgcaagg ttattcgtga
     8701 agccaacaaa ccttattcag gaacggctgt tatcgatgat tttggaccac gtcagatgga
     8761 aactggagag ttgattatct atacttcagc tgaccctgtt ttgcagattg ctgcccacga
     8821 agacattatt cctttggatg aattgtaccg tatctgtgaa tacgctcgtt cgattaccct
     8881 tgagcgtcct gcccttcttg gtcgcatcat tgctcgccct tatgtaggtg aaccaggtaa
     8941 cttcactcgt acggcaaacc gtcgtgactt ggctgtatct ccattttccc caactgtttt
     9001 ggataaattg aatgaggctg gtatcgatac ttatgctgtg ggtaaaatca acgatatctt
     9061 taacggtgct ggtatcaacc atgacatggg tcacaacaag tcaaatagtc atggaattga
     9121 tacactattg aagactatgg gacttgctga gtttgaaaaa ggattctcat tcacaaacct
     9181 agttgacttt gatgcccttt acggccatcg tcgtaatgct cacggttacc gtgattgttt
     9241 gcatgagttt gatgaacgct tacctgaaat tatcgcagct atgagagaga atgaccttct
     9301 cttgattact gcggaccatg gaaatgaccc aacgtatgca gggacggatc acactcggga
     9361 atatattcca ttgttggcat atagccctgc ctttaaagga aatggtctca ttccagtagg
     9421 acattttgca gatatttcag cgactgttgc cgataacttt ggtgtggaaa ctgctatgat
     9481 tggggaaagt ttcttagata aattggtata agatgacgcg ctatgctttg ctggtgagag
     9541 gtatcaatgt tggtagtaag aataaggtcg ttatggcgga gcttcgtcaa gaattgacaa
     9601 acttgggact ggaaaaggtt gagagctaca tcaacagtgg caatattttc tttacttcga
     9661 tagattccaa agcccaattg gtttaaaagc tagagacttt ctttgcagtc cattatccat
     9721 ttattcagag cttttcttta ctgagtctag aggactttga ggcggaactt gaaaatctac
     9781 cagcttggtg gagcagagac ttggcacgaa aagattttct cttttacact gagggtttgg
     9841 atgtggacca agtcatcgcg acagttgaaa gtttagagct gaaagatgaa gtgctttatt
     9901 ttagaaaact tgggattttc tgggggaaat tttctgaaga atcctattct aagactgcct
     9961 atcataagta cttgctgaag gtgcctttct accgccacat tactattcgt aatgctaaaa
    10021 cctttgacaa aattggtcaa atgctaaaaa ataataaagg agacacataa tgacattttt
    10081 aaacaaaatc catgaaactg ctactttcct gaaagaaaag ggaattgcag cccctgagtt
    10141 cggtctaatc cttgggtcag gacttggaga attggcagaa gaaatcgaaa atccagttgt
    10201 agtagactat gctgagattc caaactgggg ccgttcaaca gtagtcggtc atgctggtaa
    10261 attggtatat ggtgaactgg caggtcgcaa ggtcttggct cttcaaggtc gtttccattt
    10321 ctatgaaggg aatcctctgg aagtggtgac tttcccagtt cgtgtgatga aagttcttgg
    10381 atgtgaaggt gttattgtaa ccaatgcagc tggcggtatc ggatttggtc ctggtacctt
    10441 gatggctatc tcagaccata tcaacatgac ggggcaaaat ccattgatgg gtgaaaactt
    10501 ggatgacttt ggcccacgtt tcccagatat gtctagggcc tacacaccag aataccgtgc
    10561 cactgcccat gaagtggcta aaaaacttaa tatcaagctt gatgaaggtg tctatatcgg
    10621 agttactggt ccgacttatg aaacaccagc agaaattcgt tcctataaga cactgggagc
    10681 agatgcagtt ggtatgtcta cggttcctga agttatcgtg gcagcccact ctggcttgaa
    10741 agttctagga atttcatgta tcactaactt tgcggctggt ttccaagaag aactcaatca
    10801 cgaagaagtt gtagaagtga ctgaacgtgt taaaggtgat ttcaaaggct tgcttaaagc
    10861 gattcttgct gaattgtaag aaaaaagatt taaaagggga agtacctctg ttttttcagg
    10921 attgactgcc tatccggatt aaagaagaaa cagaggaata ctatgagctt cttcctgctc
    10981 ttataactga aagaagcgga agaataggta tgtctgatct gatagccagc attgtgaaag
    11041 acaagattct aggatactag cattagcttc ctagccaagc agactagtat gataaggaga
    11101 gatgagaatg aattgacttt ctgaatttct cagtcttatc atatatagca caatgagatt
    11161 tcgcttgagt ctgcttgtaa ataaacgaaa agaaagataa gaaataatga aaattggtca
    11221 acgaattatg cgctttggca taaaaaatta agtatcggag ttgtatctgt tgtagtcggc
    11281 tttgatttct agctccagct ggaatttcag ccaatgaagt aaagtaagat gtaacatctg
    11341 aagtggtaat aggtgtgtta gattctaagg aggaattgaa agagtcagaa aatgatgctc
    11401 taaaactaga aactcctctt agagaggagc caagactagc tcctcaaacg cttccggaag
    11461 caagtgaagt tagttcttga aaacaaaagg gaagagtcaa aagtagagat aacagaacca
    11521 gctcaagcgg atgatatccg caaggttgtt ggggaattag ccaaggatat aagtattact
    11581 aagttgtata tgacaggtca ttttcttgga tgttacctag ctcagattgc agcggttgaa
    11641 gcttaccaaa aatatcctga tttttataac catgtattga ggagagtgac aactttcagt
    11701 gctcctaaag tgattacttc cagaactgtt tggaatgcta agaatggttt ctgggatgtt
    11761 ggtttggaaa gtcgtaaatt agctgttagt ggaaaaatta agcattatgt ggttgataat
    11821 gacaatgttg tgactccctt gattcataat gatcgtgata ttgttacatt tacaggtaat
    11881 tcacgcttta aacaccgttc tcgtggctat tttgaaagtc caatgaatga tattcctaac
    11941 tttaatattg gtaaacaagc tacctttgat aaacatggtt atcgtgatcc gaaattggat
    12001 aaagtgcgat tctttaagaa acaggctcta cctcaatctt ctagtcaacc aagcgctgaa
    12061 ccaatggaaa atattgcctt aggaaaacag gttactcaaa gttcgacagc tttcggagga
    12121 gatgctagaa gagctgtgga tggcaaagtc gatggtaact atggtcacaa ttctgtcact
    12181 catacaaact tccaatctaa gccttggtgg caagtagatt tggctaaaga agaaaccatt
    12241 cgccaaatca atatttacaa ccgaacagac actgcccagg atagattggc aaactttgat
    12301 gtcattcttt tagacagttc tggtaaagaa attgagtgaa aacgtataac atctcctaaa
    12361 gatgtgtcag cacaaattac gattaaccat aaaaaaagcg cgctatgttc ggattgagct
    12421 agaaggctat aatgccctca gtcttgcaga agttgaagtt ttccgcttta tagctacgaa
    12481 tggtgaaacg gcgacacaag tttctaagcc agttcaacca atcagtcaga ctcctgtgaa
    12541 agataaaaca ttgacaattc aacacagtgg agcttacatt gcccgctact ccataacttg
    12601 ggaagaagtt ccagtagata aagatggaaa ccaagttgtt cgtagtcatt cttgggaagg
    12661 aaacggttgc aaccagactg caggttttgt cctcaacctc ccaatcaaag aaaatatgag
    12721 aaatctgcga gttaagattg agaaaaagac gggcctacta tggaatagat ggcaaacaat
    12781 ctatgaaaac agaccaattt tagctcaacc ccaccgtaaa attacccatt ggggtacgac
    12841 attgaattcc aaggtgagtg acgatgatgt cttgtaatct gatggtacaa tgacagttag
    12901 tttgtctagt ttataagaaa gtactacctg agcttgaata gaactcaggt agctctctgt
    12961 gaaagaacaa aattaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
    13021 ttgctcaaag cactactttg aggttgtaga taagactgac gaagtcagtc acatatataa
    13081 tccaaggcga cgttgacgtg gtttgaagag attttagaag agtataaaca gaaaggtaga
    13141 gcgcgtgttc taatttgaac acgagtagaa aacttttcta aaaacaaaaa cgaaaggatg
    13201 ggtaaactgt attcgctgaa ctgaatacgg gcgactctcc tctaaatcaa aattaagaaa
    13261 ggaattgacc ccaccctaaa agtagtggga aaaagatagt tggtctagcg agcatcgctc
    13321 actgcgccca actcctattt tcccttcgct ttttgatggg tttggtatct ttctcaatat
    13381 aaaatataaa ataaagaaag gtagagcgcg tgttctaatt tgaacacgag cggaaaactc
    13441 ggaaaataga taatctgact gaaaaatcag gatttctcgt caggttccta attttcagtc
    13501 gttttcttct cgctctttgt atcataaatt atgtctatcc atattgctgc tcagcagggt
    13561 gaaattgctg ataaaattct tcttcctggg gatcctcttc gtgctaagtt tattgcggag
    13621 aatttccttg atgatgctgt ttgttttaac gaagtgcgta acatgtttgg ttacactggt
    13681 acttacaagg gtcactgtgt atctgtcatg ggaactggga tgggaatgcc atctatttcg
    13741 atttatgcgc gtgagttaat cgtagactac ggtgtgaaga aattgattcg tgtgggaact
    13801 gcaggttctt tgaatgaaga ggttcatgtt cgtgaattag ttttggcgca ggcggctgca
    13861 accaactcaa acatcgttcg taatgactgg ccacagtacg attttccaca aattgctagc
    13921 tttgatttgc ttgataaagc ctaccatatc gccaaaaaat ttggtatgac tactcacgtt
    13981 gggaacgttt tgtcatctga tgtcttttac tcaaattact ttgaaaagaa tatcgagctt
    14041 ggtaaatggg gagtcaaggc tgtggaaatg gaagcagcag ctctttacta tcttgctgcc
    14101 caataccatg ttgatgcgct agctatcatg accatctctg atagcttggt caatccagac
    14161 gaagacacaa ctgcagaaga acgtcaaaat accttcactg atatgatgaa ggttggtttg
    14221 gaaaccttga ttgcagaata attatagcca aaaaggaagc cctttatgaa ttgtaggact
    14281 tccttttctt atccagaaat tgatctagtt ctctctgatt tcgaagaata gtgactttat
    14341 gtgaatattc ttggcaaagt ttttggtaat tttctttttg agttttgcta cgcccatccc
    14401 aaagaatcca tctgataaac tcccactcaa agcgttcagg gcaatctgcc gccatacttt
    14461 ctctgacttt tccacggtat ttaagataac gcttaaaggc tctaaagaga caggtcaatg
    14521 gcaaaaaatt gagaaagatg atttggtcag cttcttgcat tcgttcttgg tagtagcacc
    14581 aagaataatt accatcgatg acccaagctt tatgcttggt gagaaagttt tttatctcgg
    14641 ttaacatcca ttcgcagtca ctgtcttgcc aaccaggttg aaattggagt gtgtccatgt
    14701 gcagttttgg aatggagtag tagttagata acttttctgc tagagttgac ttaccagaac
    14761 cagaatatcc gataattgtg attttcattt tctacctttt cctatttgga gacaaaaaaa
    14821 cagcctctat ggactgtttc ttatttagca agtttagctg aaagacgagc tttatcgcgg
    14881 cttgctttgt ttttgtgaat caaaccttta gtttctgctt tatcgatagc tgagctagca
    14941 gcacggaaaa gttcttcaga tgggtttgct tcaaaagctt ttatagcagt acgcatagct
    15001 gatttttgag ctgagttctt ttcgttttgt ttaacgttca attcagcgcg tttgatagct
    15061 gatttaatgt ttgccaatgt tcttacctcc atatttacta actataccat tatatatgaa
    15121 aacttacgtt ttgacaaggg aaaattattt ttttaagtaa atttcatcga tttcatggtt
    15181 cttgctttta tgaagaatca cttctgcacg atttctggtt ggttcaatat aattttgtag
    15241 atttgtgaga ttgatactgg tccagacctg atgggcaaag gcttccactt ccccaatcgg
    15301 catctgagta aaacgataat agtagctatc agggtcgttt tgggctagac tcagcatttt
    15361 caagaaacgg tccagatacc aactttcaat atcatccact ccagcatcta catagatgga
    15421 aaagtcaaag aagtcagtga tatagagacg atcgttttgt ggattttgaa agacattgat
    15481 tccctcaaca attacaaaat cagcagcttt gacactttgt ttctcttcgg gtacgatgtc
    15541 gtaaacttca tgagaataga caggaatatc tacatcttgt ccatttttga tgcggtccaa
    15601 gaagttgaga agagcttcca tatcatagct ttcaggaaat cctttacgat ttaaaatccc
    15661 ctgctcaatc aaggtttgat tgggatagag aaaaccatca gttgtaacca actcaaccgt
    15721 agcatctgta aacgtacggg acagtaggat ttgaagtagg cgactggttg tggattttcc
    15781 aacggcaaca ctcccagaaa ccccaataat aaaaggttga gatttacttt cacgttggag
    15841 gaaaattcct tttgaaaagg ctaaatcttc cttagttcgc ttgtaaatct gaatcagatg
    15901 agccaagggg agatagatat ctgtaacgtc ttggagactg atttggtcat taaaactctt
    15961 gatagattcc aattcttctt ctgtcaaagg aggtgttgtc tttcgatgta aagattgcca
    16021 agtctggcgg ctgatttttt caaaatgtaa aaattcgttg gtcatttgtt ttcccctaga
    16081 tattttgtct atcataccat aaaaatctaa aaaaataaag cggtttcttg aatgtggtaa
    16141 gtcaatggta tatagtataa gtgatcaatt tattgatgaa ataggagata gattctactg
    16201 atttataagt ttataagctt ataaaggggg ctttttagtt cacaacttat aggaggtgta
    16261 ctatgaaaat cttaaaacgt tacatattgg aactctgttt tattttaagt tttgctttac
    16321 cttttataaa aggagccaat gcagataatg gtatatgctt tgtggaaacc tattacggtt
    16381 ttactttttt gatggaacat gctattgtaa cagctgtctt tatctattcg ttttcaattg
    16441 ctttcttact aaaaaaacga tgggcgaaat ggattgctgc tggtagttat tgctttttag
    16501 tcctatggat tgcgacagag ggttatttct tccgcatgtc actagaagat ttgatacgac
    16561 tttggacaag tttggaaatc ctgacacaaa cgtatcagtt gggcttttat ctaaacattt
    16621 tgttgggaat tttgttgata ataaagtatt ttaaggttaa gcaatagaaa taataatctg
    16681 cctgattata gatgataaac tttttgtttt tatctggact gtgatattta tagttctaaa
    16741 tggtttatta tttataagtg ttgaaagaga ttgaagaaaa tggcttcgtg actcgctttc
    16801 ttcggtcttt ttcgttttat tatcaatttg taaacgattt acaatttgag tcaaattatg
    16861 gtaaaatagt gtcatgagta aaatgtatta tgcagaaaat cctgacgctg ctcacgacat
    16921 tcatgagttg agagtagagt tgttgggaca aaaaatgacc tttttaacgg atgcgggtgt
    16981 ttttagcaag aaaatagttg actttggaag tcaactattg ctcaagtgtc ttgaggtcaa
    17041 ccaaggagaa actgtccttg atgtaggctg tggttacgga cctttgggtt tgtccttagc
    17101 taaggcttat ggagttcagg ctactatggt tgatatcaac actcgtgcct tagatttagc
    17161 tcggagaaat gctgaaaaaa ataatgcaaa agcgacgatt ttccagtcca acatctatga
    17221 acaagttgaa ggacattttg atcatgtcat ttccaatcct cctatccgtg cgggcaagca
    17281 agtcgttcat gaaatcattg agaaaagtaa agatttcttg gaaactggtg gggatttgac
    17341 aatcgtcatc cagaaaaaac aaggggctcc aagtgctaag tccaagatgg aggatgtgtt
    17401 tggtaattgt gaaatcctta aaaaagacaa aggatactat atccttagaa gtgtgaaaga
    17461 atgagagcag ttgatttaat acaaaaaaaa cgagacggtc aagaactgac ttcaagtgaa
    17521 attgaatggc tggtagaagg ctatgtgtca ggaactgttc ctgattatca gatgtctgcc
    17581 tttgctatgg ctgtttattt taaaggaatg acgactcgtg aaatttctga tttaacgatg
    17641 aatatggtta agactgggca agagtttgac ctgtcagcca ttgatggtgt gaaagttgac
    17701 aagcattcta ctggtggtgt cggcgataag gtaaccttga ttttagctcc tcttgttgct
    17761 agcttcggtg tgcctgtagc aaaaatgagt ggtcgtggtc ttggccatac aggcggaaca
    17821 attgataaat tggagtccat taggggctat caagtagaac gtagtcaaga ggattttatt
    17881 cgtcaggttc aggatattgg agtatctgtc attgggcaat cagaccagct ggtcaaagca
    17941 gataagcttc tctatgccct tcgtgatgtg accgcaactg tcgacacgat tcctttgatt
    18001 gcgagttcgg tgatgagcaa gaaaatcgcg gcaggggcgg atgctatttt gctagacgtg
    18061 actgtcggtg agggtgcctt catgaagacg gttgatgagg cgcgtgagtt ggctcaaact
    18121 atggtagatc ttggtaaggt tgttggacgg aagacagtag cagtgattac ggatatgagc
    18181 cagcctttgg gacgagcgat tggaaatcgt ctggaaatcc ttgaagcatt ggagattttg
    18241 caaggtcaag gacgtcagga tattacccac tttatttgtg aattggctca aattatgctt
    18301 ggcttggcaa atgttaacaa gactgttgaa gaagttcgcc aacatcttga ggatggtcaa
    18361 gcactggcta agtttgagga aatggtgcaa gcccaaggtg gagacttgga agacctctat
    18421 cgtcctgtaa atgtagctca tgtggtggaa atccctgctc aggaaacagg tgtcatttca
    18481 gctcttccag ctatggactt tggtctttat gccatgaggc tgggtgctgg tcgtgcagtt
    18541 aagtctgatg ccttggacta tgaaacagga attgtttttg aaaagaagat tggagactcc
    18601 gttcaaaagg gtgaaattgt tgcaaaagta tacacaaatg aaaaaattcc acctcaacta
    18661 gttacagatt tccaaaaatg tgttaaaata agtgatgaag tgaaaaaaat ccgtgaaatt
    18721 gtagaaatca tctcctaaat ggagggaaaa ccgaaatgaa attaaataaa tatatagatc
    18781 atacgctttt aaaacaagat gcaaagaaaa aacaaattga tagtttgttg tctgaggcta
    18841 gagagtatgg ctttgccagt gtttgcgtta atccaacctg ggttgaacat gctaaaaaag
    18901 ggcttgaagg cacagatgtt aaggtttgca cggtagtagg tttccctttg ggagcaacaa
    18961 cttcagccgt gaaagcattt gagacaaaag aagctatcca aaatggtgca gatgagattg
    19021 atatggtgat caatgttgga gctctcaaat caggtaattt agccttggtt gagtcagata
    19081 ttcgcgcagt agtggaagca agtggtgata agttagtgaa agtcattatt gaagcttgcc
    19141 ttctgacaga ccaagaaaaa gttgttgttt gccaattggc ccaaaaagct ggggctgact
    19201 ttgtcaaaac atctactggc ttttcaactg gtggtgctac gatagcagat gttacattaa
    19261 tgcgtgaaac agttggatct gatatgggag tcaaggctgc tggtggagct cgttcttatg
    19321 cagatgctct tgcctttgtc gaagcaggtg cgacccgtat cggaacgtca gctggggtag
    19381 ctattttaaa aggagaattg gcagatggcg actactgagt tgattgaact ggcaattgaa
    19441 accagcaaac atgcctatgt cccctattct cactttccta tcggagcagt tttagtagcc
    19501 aaagacggaa atgtttacac gggagtgaat atcgaaaatg ctagctatcc tttgaccaat
    19561 tgcggtgaga gaacagctat ttttaaggct atatctgaag gccaaagaga attttcagaa
    19621 ttgattgtct atggtcaaac tgaaaaaccg atttcaccat gtggtgcttg tcgccaagta
    19681 atggtcgaat tttttgaaca agatttaaaa gtgaccttag tcgcaaaaga taaatcgacg
    19741 gtcgagatga cggtcgggga gttacttcca tattctttta cagacttaaa ttagtctgag
    19801 tcgctctttg agtggcaagg gtctttgtga ccaatcaatc catacttgca acatcgttgc
    19861 acatcttatt taggaggttc agtaatgaac aagaaacaat ggctaggtct tggcctagtt
    19921 gcagtggcag cagttggact tgctgcatgt ggtaaccgct cttctcgtaa cgcagcttca
    19981 tcttctgatg tgaagacaaa agcagcaatc gtcactgata ctggtggtgt tgatgacaaa
    20041 tcattcaacc aatcagcttg ggaaggtttg caggcttggg gtaaagaaca caatctttca
    20101 aaagataacg gtttcactta cttccaatca acaagtgaag ctgactacgc taacaacttg
    20161 caacaagcgg ctggaagtta caacctaatc tttggtgttg gttttgccct tcacaatgca
    20221 gttgaagaag cagctaaaga acacactgac ttgaactatg tcttgattga tgatgtgatt
    20281 aaagaccaaa agaatgttgc gagcgtaact ttcgctgata atgagtcagg ttaccttgca
    20341 ggtgtggctg cagcaaaaac aactaagaca aaacaagttg gttttgtagg tggtatcgaa
    20401 tctgaagtta tctctcgttt tgaagcagga ttcaaggctg gtgttgcgtc agtagaccca
    20461 tctatcaaag tccaagttga ctacgctggt tcatttggtg atgcggctaa aggtaaaaca
    20521 attgcagccg cacaatacgc agccggtgca gatattgttt accaagtagc tggtggtaca
    20581 ggtgcaggtg tctttgcaga ggcaaaatct ctcaacgaaa gccgtcctga aaatgaaaaa
    20641 gtttgggtta tcggtgttga ccgtgaccaa gaagcagaag gtaaatacac ttctaaagat
    20701 ggcaaagaat caaactttgt tcttgtatct actttgaaac aagttggtac aactgtaaaa
    20761 gatatttcta acaaggcaga aaaaggagaa ttccctggcg gtcaagtgat cgtttactca
    20821 ttgaaggata aaggggttga cttggcagta acaaaccttt cagaagaagg taaaaaagct
    20881 gtcgaagatg caaaagctaa aatccttgat ggaagcgtaa aagttcctga aaaataatgg
    20941 atggaagtca tttcttagga agcggccaag ggccgctttt ttaagagttg agacaaagtc
    21001 attttgtctc agtaaagctt gctactagac aaactagcaa gttttattga aataaaataa
    21061 gactctgaaa ggaagagcac atggcacacg aaaatgtcat tgagatgcgt gatattacca
    21121 aggtgtttgg tggatttatt gccaacgaca aaatcaactt gcacctacga aaaggtgaaa
    21181 ttcatgcact tttaggagaa aatggggctg gtaagtccac gctaatgaac atgttagcag
    21241 gccttcttga accaactagt ggtgaaatcg cggtcaacgg tcaagttgtc aatctcgact
    21301 ccccatctaa agcagctagc ttgggaatcg ggatggttca ccagcacttt atgttggttg
    21361 aagccttcac agtggctgaa aacatcattt taggtagtga attgactaaa aatggtgtgc
    21421 tagatatcgc tggagctagc aaagaaatca aggctctttc tgaacgttat ggcttagctg
    21481 ttgacccttc tgccaaggta gcagatatct cagttggagc ccaacaacgt gtagaaattt
    21541 taaaaacact ttataggggg gctgatatcc ttatctttga cgaaccaacg gctgttttga
    21601 ctccatcaga aattgatgag ttgatggcta ttatgaaaaa tcttgtcaaa gaaggaaaat
    21661 caattatctt gattacccac aaattggatg aaattcgcgc agtttctgac cgtgttacag
    21721 ttatccatcg tgggaaatca attgaaaccg ttgaaattgc aggggctacc aatgctgatt
    21781 tggcggaaat gatggtagga cgttctgttt cctttaaaac agagaagcaa gcctctaaac
    21841 caaaagaagt ggttttgtct atcaaagatt tggtggtcaa tgaaaaccgt ggtgttccag
    21901 ctgttaaaaa tctgtccttg gatgttcgtg ctggagagat tgttggtatt gcggggattg
    21961 atggaaatgg tcagtctgaa ctgattcaag ccattacagg tcttcgtaag gttgaatctg
    22021 gtagcattga gctaaaagga gattcaattg taggcttgca cccacgtcag attacagaac
    22081 taagtgttgg gcacgttcca gaagaccgtc accgtgatgg cttgattttg gaaatgatga
    22141 tatctgaaaa tattgccctt caaacctact ataaagaacc acatagtaaa aatggaattt
    22201 tgaactattc aaatattact tcttatgcta aaaagctgat ggaagagttt gatgttcgcg
    22261 ctgccagtga attagttcct gcagctgcac tctcaggagg aaatcaacaa aaagcaatta
    22321 ttgctcgtga aattgatcga gatcctgatc tccttatcgt tagccagcca actcgtgggt
    22381 tggatgtcgg tgccattgag tatatccaca aacgcttgat tgaagagcgt gataatggca
    22441 aggctgtcct tgttgtcagc tttgaattgg atgagatttt aaacgtctca gaccgtattg
    22501 ccgttatcca cgatggtaag attcaaggta ttgtatcacc agaaacaacc aataaacaag
    22561 aacttggtgt cttgatggct ggtggaaact tgggaaagga gaagagtgat gtctaaaaaa
    22621 ttacaacaaa tttcggttcc cttgatttct gtatttctag gaattttact cggagccatt
    22681 gtcatgtgga tcttcggtta tgatgctatt tggggctacg aagaattatt ctatacagcc
    22741 tttggcagtc tgcgtgggat tggagaaatc ttccgtgcta tgggtcctct ggtcttgatt
    22801 ggtcttggtt ttgcggttgc cagtcgagct ggtttcttta acgtcggact tcctggtcag
    22861 gctttggcag gttggattct cagtggttgg tttgcgctgt cgcatccaga tatgccccgt
    22921 cccttgatga ttctagcaac catcgtgatt gccttgattg ctggtgggat tgtcggagcg
    22981 attccaggta ttcttagggc ctatctaggg acgtcagagg ttattgtaac catcatgatg
    23041 aactacattg tcttgtatgt agggaatgcc tttatccatg ctttccctaa agacttcatg
    23101 caaagtacag attcgaccat tcgtgttggg gctaatgcaa cctatcagac accttggttg
    23161 gctgagttga ctggtaactc acggatgaat attggtattt tctttgccat cattgccgtt
    23221 gcagttattt ggttcatgct caagaaaaca actcttggtt ttgaaatccg tgcagttggt
    23281 cttaatccac atgcttcaga atatgctggt atttctgcca agcggactat tatcctatct
    23341 atgattattt caggtgcctt ggcaggtctt ggtggagctg ttgaaggttt gggaaccttc
    23401 cagaacgtct atgttcaagg ttcgtcatta gctatcggat ttaacggaat ggcggttagt
    23461 ttgcttgcgg ccaactcacc aattggtata ctctttgcag ccttcctatt tggcgttctc
    23521 caagttgggg ctcctggtat gaatgcggcg caggtaccat ctgagcttgt cagcattgta
    23581 acagcgtcta ttatcttctt tgtcagtgtt cattacctta tcgaacgctt tgtcaaaccg
    23641 aaaaaacaag ttaaaggagg taagtaaaga tgtctattat aaccttgctc cccctcttgg
    23701 tgtcttctat gctgatttac tcagcacctc tcatctttac aagtatcggt ggtgttttct
    23761 ctgaacgtgg tggtgtggta aacgttggcc ttgaaggaat tatggttatg ggtgcctttt
    23821 ctggagttgt ctttaacctt gaatttgcag aacaatttgg agcagcaact ccatggctat
    23881 ccttgcttgt agcaggattg gttggtagtg ttttctctat catccacgca gcagcgacgg
    23941 ttcatttccg tgcagaccat gttgtcagcg gtacggtatt gaacttgatg gcgcctgcct
    24001 tggctgtttt cttagttaaa gttctttata acaaaggaca aaccgacaac ctaagtcaaa
    24061 cttttggacg ctttgatttc ccagtcttgg caaatatccc agtgattggt gatatctttt
    24121 tcaagtcaac tagtctactt ggttatctgg cgattgcctt ctcattcctt gcttggttta
    24181 ttctctttaa gactcaattt ggtcttcgtc tccgctctgt cggtgaacat cctcaagcag
    24241 cggatacctt gggaatcaac gtctacaaga tgagatattt agggattatt atttcaggtt
    24301 ttctaggtgg aattggcgga gcgatttatg cgcaatcaat ctcagttaac ttctcagtga
    24361 caactattgt tggacctgga tttatcgccc ttgctgcgat gatctttggg aaatggaatc
    24421 caatcggtgc tatgctttct agtctcttct ttggactttc acaaagtttg gctgttatcg
    24481 gttctcaatt gccgttccta caaggagtgc cagcggttta tcttcaaatt gcaccttatg
    24541 ttttgacaat tcttgtctta gcagccttct ttggaaaagc agtcgcacca aaagcagatg
    24601 gtatcaacta catcaaatca aaataagcat acaaaaaaac gtcagtccaa tgactgaact
    24661 gccccccaaa agttagacag aaaaaatcta acttttgggg tgtttttatt atgaaattaa
    24721 gttatgatga taaagttcag atctatgaac taagaaagca aggatatagc ttagagaagc
    24781 tttcaaataa atttgggata aataattcta atcttaggta tatgattaaa ttgattgatc
    24841 gttacggaat agagttcgtc aaaaaaggaa aaaatcgtta ctattctcct gatttaaaac
    24901 aagaa
//
LOCUS       DBEJZV010000026        24148 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.26, whole genome shotgun sequence.
ACCESSION   DBEJZV010000026 DBEJZV010000000
VERSION     DBEJZV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24148
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.26"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..490
                     /locus_tag="ACL3S0_001475"
     CDS             <1..490
                     /locus_tag="ACL3S0_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGR1312367.1"
                     /translation="RKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILN
                     KLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKE
                     KIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLS
                     RA"
     gene            complement(589..2211)
                     /gene="groL"
                     /locus_tag="ACL3S0_001476"
     CDS             complement(589..2211)
                     /gene="groL"
                     /locus_tag="ACL3S0_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGR1312368.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2227..2511)
                     /gene="groES"
                     /locus_tag="ACL3S0_001477"
     CDS             complement(2227..2511)
                     /gene="groES"
                     /locus_tag="ACL3S0_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGR1312369.1"
                     /translation="MLKPLGDRLVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2667..3062)
                     /locus_tag="ACL3S0_001478"
     CDS             complement(2667..3062)
                     /locus_tag="ACL3S0_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGR1312370.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3140..3901)
                     /locus_tag="ACL3S0_001479"
     CDS             complement(3140..3901)
                     /locus_tag="ACL3S0_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR1312371.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3943..4569)
                     /gene="ytpR"
                     /locus_tag="ACL3S0_001480"
     CDS             complement(3943..4569)
                     /gene="ytpR"
                     /locus_tag="ACL3S0_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGR1312372.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFETAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(4585..4902)
                     /locus_tag="ACL3S0_001481"
     CDS             complement(4585..4902)
                     /locus_tag="ACL3S0_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGR1312373.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(4899..5198)
                     /locus_tag="ACL3S0_001482"
     CDS             complement(4899..5198)
                     /locus_tag="ACL3S0_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGR1312374.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5396..5476)
                     /locus_tag="ACL3S0_001483"
     CDS             complement(5396..5476)
                     /locus_tag="ACL3S0_001483"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312375.1"
                     /translation="MASSSKMFRNTYTPDGYYVGNLGAWQ"
     gene            complement(5483..5674)
                     /locus_tag="ACL3S0_001484"
     CDS             complement(5483..5674)
                     /locus_tag="ACL3S0_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGR1312376.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5835..6509)
                     /locus_tag="ACL3S0_001485"
     CDS             complement(5835..6509)
                     /locus_tag="ACL3S0_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312377.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            complement(6515..6961)
                     /locus_tag="ACL3S0_001486"
     CDS             complement(6515..6961)
                     /locus_tag="ACL3S0_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR1312378.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7075..7578)
                     /locus_tag="ACL3S0_001487"
     CDS             complement(7075..7578)
                     /locus_tag="ACL3S0_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR1312379.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7575..7937)
                     /locus_tag="ACL3S0_001488"
     CDS             complement(7575..7937)
                     /locus_tag="ACL3S0_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGR1312380.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8003..9034)
                     /locus_tag="ACL3S0_001489"
     CDS             complement(8003..9034)
                     /locus_tag="ACL3S0_001489"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312381.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            complement(9041..9862)
                     /locus_tag="ACL3S0_001490"
     CDS             complement(9041..9862)
                     /locus_tag="ACL3S0_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312382.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPA
                     SMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVVVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIIFMSYAM"
     gene            complement(9878..10348)
                     /locus_tag="ACL3S0_001491"
     CDS             complement(9878..10348)
                     /locus_tag="ACL3S0_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR1312383.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(10472..11188)
                     /locus_tag="ACL3S0_001492"
     CDS             complement(10472..11188)
                     /locus_tag="ACL3S0_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1312384.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12069..13484)
                     /gene="ply"
                     /locus_tag="ACL3S0_001493"
     CDS             complement(12069..13484)
                     /gene="ply"
                     /locus_tag="ACL3S0_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGR1312385.1"
                     /translation="MSNKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALMKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13495..13905)
                     /locus_tag="ACL3S0_001494"
     CDS             complement(13495..13905)
                     /locus_tag="ACL3S0_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312386.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDHLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(13898..14506)
                     /locus_tag="ACL3S0_001495"
     CDS             complement(13898..14506)
                     /locus_tag="ACL3S0_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312387.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14519..14977)
                     /locus_tag="ACL3S0_001496"
     CDS             complement(14519..14977)
                     /locus_tag="ACL3S0_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGR1312388.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15102..15501
                     /locus_tag="ACL3S0_001497"
                     /pseudo
     CDS             15102..15501
                     /locus_tag="ACL3S0_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            16003..16863
                     /locus_tag="ACL3S0_001498"
     CDS             16003..16863
                     /locus_tag="ACL3S0_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HGR1312389.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGKKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLDKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NVMYMPIIKTIEELDFVLSFEGINTVAVELVFQDLENPIISKKIIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     IKENYHVQKL"
     gene            16847..17908
                     /locus_tag="ACL3S0_001499"
     CDS             16847..17908
                     /locus_tag="ACL3S0_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR1312390.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTDFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNDLKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            17925..18929
                     /locus_tag="ACL3S0_001500"
     CDS             17925..18929
                     /locus_tag="ACL3S0_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312391.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSATQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIKEKVTMYINPRDIMQF
                     "
     gene            18941..20635
                     /locus_tag="ACL3S0_001501"
     CDS             18941..20635
                     /locus_tag="ACL3S0_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312392.1"
                     /translation="MRKSLNWKDCLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEAAKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIVAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            20637..21338
                     /locus_tag="ACL3S0_001502"
     CDS             20637..21338
                     /locus_tag="ACL3S0_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGR1312393.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSLEG
                     YNRLLIYLNTSGIKILEIQNGIGNLDEERQLNKIKSTKVSCYLSLKLNENFEHLKLME
                     EMHNIAGVIYVEEIR"
     gene            21385..21984
                     /locus_tag="ACL3S0_001503"
     CDS             21385..21984
                     /locus_tag="ACL3S0_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR1312394.1"
                     /translation="MNIIFDLGNVLIEWNKEKILSKICKNDLEYNLFNKFVFQSNLWI
                     DLDNGKISLEFLENQLIDEMGHQYQDQIHELVWNWFNYVDLYDEVYELIKQLKKKNFQ
                     IYVLSNTSSIFHILLDSVLSKVSSVLDGYVISCEVKMMKPQKEIYLSLVNKYQLDIKD
                     CIFLDDLEENVEAARTLGIKAFQIKERKEISNILKDLLN"
     gene            21994..24021
                     /locus_tag="ACL3S0_001504"
     CDS             21994..24021
                     /locus_tag="ACL3S0_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR1312395.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIPIFEVDTYQSNKTLSSFDSDKIFEIVLEL
                     VRTEKLSNLYFISLTNEKEHSLFEYLTQKIKNSTHIQVQERLQLLSLYPTLKNFAKYD
                     CIFVDDEDLMHTLLDLFDWFTIIDRPKICLIGSRVWFEKRNLFYIHLDYRILALNTAE
                     NLESGNSSIVPVKDGKQILTNQLFDGECDDIYLLTVHSPMNKALEILSEKYKQISGKN
                     IKIIEKRYDELLEMIESGDVSSSFDMIRMDMAWLPTFGKKYFQEITSFRQTKSINQNI
                     SKSVSREYMYIDQKQYTFPLDVSSQILVYRKDLFEDSFLQRRYFEKTKRKLTVPKSYQ
                     EFDELSEFFTLTENPFSPTLYGHSLALSSSVRAACEFIPRFRERLAQSRMNLAVLPQV
                     LTEYEKSYQFTEKSFNSSWNDFVTNLNSGKTSMEIIFSNYTSPLFDGLNVSAQFEFAT
                     ATIPGNTPVIGGGSIGISKYSNRVEECLNFINWLYSEEISILLTSLGGFLPSKYVMQN
                     RMLQFQYPWLSSLEDTFSIGSRTKWYGFNTDFRFEQMLGQELIESVKHRYG"
BASE COUNT         7618 a         4691 c         4288 g         7551 t
ORIGIN      
        1 tcgaaaatcc catgaataca aggctatcaa gcgctactgg aaactcattc aacaggatag
       61 ccgtaaactg agtgataagc gattttatcg tcctactttt cgtatgcact taaccaataa
      121 agagatttta aacaagcttt tgagctattc ggaagacttg aaacaccact atcagctcta
      181 tcagctcttg ctttttcact tccagaacaa ggaaccagag aaatttttcg gacttattga
      241 ggacaatctt aagcaggttc atcctctttt tcagactgtc tttaaaacct tcctcaaaga
      301 taaagaaaag attgtcaacg cccttcaact acactattct aatgccaaac tggaagcgac
      361 caataatctc atcaaactta tcaagcgcaa tgcctttggt tttcggaact ttgaaaactt
      421 caaaaaacgg atttttatcg ccctgaatat caaaaaagaa aggacgaaat ttgtcctttc
      481 tcgagcttag ctgacttcaa cccactacag ttgacaaaga gcctataaaa agaagggtta
      541 gtcattccct ccttttgtgt tttttataag ttgttttcta tagaaagctt acatcatccc
      601 gcccatcata cttggatcca ttgctggagc tggggctact ggttctggtt tattggctac
      661 gactgcttct gttgtcaaaa tcaagctggc tacagatgct gcattttgta gggctgaacg
      721 actcacttta actggatcaa tgataccttg atcaatcatg ttaacccact cgccagttgc
      781 tgcgttaaat cctataccaa gctcagcatt tttcaaacga tcgataacga tagatccttc
      841 aaatcctgca ttgtgagcaa tttgacgaac gggttcttcc aaagcacgga gaacaatatt
      901 acgtcctgtt gcttcatctc ctgtcaattc caaggtagca acagctggaa tcacattggc
      961 aagagctgtt ccaccgcctg caacaatacc ttcttcaaca gctgcacgag tagcgttgag
     1021 ggcatcttca atgcggagtt tcatttcttt caactcagtt tcagttgcgg ctccgacctt
     1081 aataaccgct acaccacctg acaatttggc caagcgttct tgcaattttt cacggtcaaa
     1141 ttcagaagtt gtagtttcga tttgagactt gataaccgca acacggtgag aaatcgcttc
     1201 aggatttcct gcaccttcta caataaccgt gctatctttg tccacggtca ctctcgctgc
     1261 ttgaccaaga gcttcaattg tcgcatcttt caactcaaga ccaaggtctt ctgtgataac
     1321 tgttccgcct gttaagatgg cgatatcttc aagcatggct ttgcgacggt caccaaaacc
     1381 aggtgccttg actgctacta cgttgaaggt tccacgaatc ttgttcaaaa caagagttgg
     1441 aagagcctcg ccatccacat catccgcaat aatcaagagt ggacgattgc tttggagaat
     1501 gctttccaaa agtggcaaga tctcttggat attggaaatt ttcttgtctg taatcaaaat
     1561 gtacggattt tcaaggtcag ccaccatttt ttcgctatct gtcaccatgt actgtgaaag
     1621 gtaaccacgg tcaaactgca ttccttctac gacttcaagc tctgtttcca taccacgtga
     1681 ctcttcgatg gtgatgacac cgtctttgcc aactttttcc attgcttcag agatgtactc
     1741 accaactttt tcagaacgag aagatacggc tgcaacttga gcgatagctt ctttattggc
     1801 aacagggatg gcgttgtttt tcaaagcttc aactgctgcg gcaactgctg tttcaatccc
     1861 acgacgaata ccgattggat ttgcacctgc tgtgacgttt ttgattcctt cacggacgat
     1921 agcttgggtc aagactgttg cagtcgtagt cccgtcacct gcgatatcat tggttttaga
     1981 agctacttct gataccaatt tggcacccat attttcaaaa tggtcttcta attcaatttc
     2041 tttggcaata gtcacaccgt cattggtaat caatggtgag ccaaatgatt tttcaagaac
     2101 gacattgcga ccttttggtc ccaaggttac tttaacagta tctgcaagga tatcgacacc
     2161 acggaccata gctgaacggg catctgatga aaatttaatt tcttttgaca tacttacttt
     2221 ctccttctat tcttcaatga ttgccaagat gttagcttcg cctacgatga tatacttttc
     2281 atcgccatct ttgacatcaa gacctgcgtg ggcttcaact aagacacggt ctccagtttt
     2341 aacacttgga gcaaccaagt caccgttcaa ggtacgaaca ccttgtccag tagccacaac
     2401 ttgggctgtt ttggtttttt cttgggctga acctgcgaga acaaagcctc caacagtttg
     2461 ttctttttct tctactttta agaccaaacg gtcccctaat ggtttcaaca tctgatttcc
     2521 tccataatga gatagatatt attagcactc tttatacctg agtgctaatt catagttcta
     2581 ttgtatcact tagtcagaaa taatcaagaa aaaagtctga ctttctcaag ataaaaagcc
     2641 tgagaccaac tcagactttt taattcttaa aatggcaatt cttcctcttc caagaccaaa
     2701 tctgccaaat cttggcctgc attattttca cgcatagcac gttgggcacg actttccaag
     2761 agttggaatc ctgtcacaag gacttcggtt acataattca tctgaccatt tttctcaaag
     2821 cgacgggtac gcaattctcc atcaacggaa atgagactac ctttggttgc gtagcttgcc
     2881 aaagtttctg ctagtctgcc ccataggacc atattgacaa aatcaacttc acgttcaccg
     2941 ttttggtctt tgtaacgacg gttgacagcg atagttgctc gcgctactga cttgtcattg
     3001 ttggttttgt gcaattctgg tgtagacgtt aaacgtccaa tcaagataac tttattatac
     3061 atattttctt cctcctactt atctattcgt aggaaatcaa aaaaagttac agaaatttgt
     3121 aacttttcga gaaaattttt tattttttat gaaccatgaa acctgtcgcc tgttgattgg
     3181 ccataatggt catatctgta atctgaacac gacgaggttg actagtcaca tagactactg
     3241 tatctgcaat atcctgagct tgcaaagctt ctattccttg gtaaacggac gcagctcgtt
     3301 ctttatcacc atgaaaacgc actgtagaaa aatctgtttc gacaattcca ggctgaatgg
     3361 ttgtcacctt gatatccgtt gcgatggtat caattcgcag tccatccgaa aaggtcttaa
     3421 ccgcagcctt ggtagctgag taaacagcgg caccagcata ggcgtagatt cctgcggttg
     3481 accccatatt gataatatga ccttgattga cttttatcat tgctggcaag aaacagcgag
     3541 taaccgccat cagaccttta acattggtat ccaacatggt caacatatcc aactcctcat
     3601 agtcttgata gggagccaag tcaagagcca gtccggcgtt gttgaccaag atatcaatcc
     3661 tccctatcgt ttctagaata tcagagcaaa cagtcttcac catgaccata tccgtcacat
     3721 ctagtggaaa agtccagacg gtttgatttg gaaagcttac tgcaaactcc gacttgagga
     3781 tttctaatct gtctatccgt cgtcctgtta gaacgacatc ctcaccctgc tccagataag
     3841 cacgcgcaat cgcttcaccg attcctgagg ttgctcccgt aatcacaaca ttttttgcca
     3901 tcttatttcc ttctagctgg tctatcagat attaacaact tcttaggcag tccagtgttt
     3961 agctgagtca aatggtgttc cgacaacttg gtcttctgat aattcaagca ccccacgttt
     4021 ttgtggagca tttggcagat gcaattcacg aggactgcac atcataccaa aactcttttc
     4081 accacgaagt tcacctggga aaatgagatt cccttttggc atcatagctc caggaagcgc
     4141 gacaatggtt ttcaacccca cacgcgcatt gggagctcct gcaacgattt gtacagtctt
     4201 atcacttgcg actgcaactt ggcagatgtt gaggtggtca ctatctggat gggctaccat
     4261 ctcaacaatt tcaccgacaa caaacttagg ttccttatca ttaacaattt cttctgtaaa
     4321 accttccgcc tgcaactctt ggttcaaacg agcgacttgc tcatctgtca aaaagacttg
     4381 accgcgctct gcagtttcaa ataaacttga aacttcgaaa atattccaag ccactgtttc
     4441 cccattatct ttgagaaaaa cacgggctac cttgcctttg cgctccacat ccagtttggc
     4501 atctccgcta tttttcacga tgaccataag gacatcaccg acatgttctt tattatatgt
     4561 aaaaatcatt gtttcctttt tctcctattt cagtcctgct aaaaagtcat tgatttgttg
     4621 cttgctttta cggtcgcgat tgacaaaacg accgatttcc ttgtcctttt ctagaacaac
     4681 aaggctagga attccgtaaa catcccagag tttggccaaa tccatatact gatctcggtc
     4741 cattcgaata aaggtgaact ctggattggt ctcctcaatc tctggtaagg caggataaat
     4801 ataacggcaa tcgccacacc agtctgccac aaaaaggaag accttcttgc ccgctttttc
     4861 cactaaagat gctaattctt ctaaacttgc tggctgtatc ataagacttc ctcctcatag
     4921 actaggtctt cattttcata gacaaaggta taatgacggc catcctcaaa aatgacgcca
     4981 ccaaccaagc tctccagact gctttcgtaa acttgaacat agagggtcgc aatttccccc
     5041 atgtcggaaa aatggtctcg cacaatctct gtcaactctt cctgagtctt catgagctta
     5101 cggtcatctg caactttttt cgtagcaaga gcaaggcttc caatacctag cagagccaag
     5161 cctgccatcc acattttttt agctttcata ccattcattt taacacaaaa aaggcttcag
     5221 gacaaatgag gaagcagcag aaaagcaagt aaaaagcctc ttcctttaag gaaaaggact
     5281 tcgtatacta agagcaaact aggaagctag ccgcaggctg ctcaaaacac ggttttgagg
     5341 ttgtagataa ggcgacgctg acgtggtttg aagagatttt caaagagtat tattcttatt
     5401 gccaggcacc taagttgcca acgtagtaac catcaggtgt gtaggtattg cgaaacatct
     5461 tacttgatga agccagataa tactacttgc cattgtcttt gacccaatca ttcgcaatca
     5521 tggaaccaga agaacttaca taataccatt ctcccttgtc ataaacccaa gtactgactt
     5581 tcatggttcc tgagcaatta aaggcaaaaa aactgtccaa tatcattcgt tttttaaaag
     5641 catttgacac tacatcatct acgctgtagt acatagatac atcaaacgta aaagccaaaa
     5701 tatcgaaaaa tatacaactt ttaaaggcag catttcattt tttaaagtct aacaaccata
     5761 gaactgaaat cagagcaagg catcaatttc ctactcttag tacgtctatt ttgatggttg
     5821 aagtgaagat ttttttattt aacgtagaca agctccaact tcccaaaggc cacgtctcca
     5881 cgaataatca aggttttgct tgttggcgct acaggagcgt ccgccttggc tgcaccaaag
     5941 gatgtttcta ctttcaaatc gacacgccag tgttgtggaa catagacggt tgcatttccg
     6001 aaggccactt caatatttaa agttgcaaaa tcacctagca tctctgcatt atcatagtag
     6061 attttagcat ccccaaaagc gacttccact tggtcatcta cgagatcttg atcttgctta
     6121 tagaaggtcc cgctaccaaa agcgacttcc ttatccgtga cgactgtttt tttcccattg
     6181 taccaccatt ttttttcatt ccagaactta cttgaatgcg tcagataacc aacaccaagt
     6241 accaccaaga tgctagccca aataagagaa tgattggtaa ctggtaacaa gtcataagcg
     6301 taatttgcaa tgatgagcgc cagtaaacct gtaaaaactg ccgaagtgag atgacgtcta
     6361 aggatggact caatggactt ataagcaaaa aaaacaatac ctagtaaagg ccatatttta
     6421 ccatccaaag aaggaattcc aaaattccct tgcagcaaga tccaagctgc taaaaccaat
     6481 aaaacaatac caaatgcttt ctttttcatg ttttttacct catgtttctt agattttctt
     6541 ttaggaggga ttggtaatgc cgtgagacat gaacctcctt gtgcgtctga taaaaggaaa
     6601 tggtgcccgt tcctgaaaag gacttgtcca ctgagtaaat ctgacggatg tttgcgatcg
     6661 ttgacttgga aactcgatta aaatagcgag gcaagataga ctccaactca tagagcttga
     6721 ggcgaacctc ataagcttcc ttctggttat gagcgtagat cttgctccct tctgtttcaa
     6781 agaagagaat ttctgacagg tctagataat attcacctgt ccccttgtaa aaagtcaacc
     6841 tcggagcctt tgactcttgc aagagccgtt gcaagtctgc aatttcatct gtcaaagtgg
     6901 gggtcttgat gacaatttca gtctcctcta aattgccgtc aatctcaatt cgtaacttca
     6961 tcacatctcc tttctgactc tactatatca aagctaaatt aggaatacaa gggcaaaaaa
     7021 gcaagtggtc aatttgaagc agtaagtggt tgtaggacta gcttaactta catgtcagaa
     7081 taggaagaaa aggaatcccc acaccaaacc acaagcatag ccaaccaaga catccttggg
     7141 ataatgaaca ccccctaaaa ccctcaccaa ccccagcaaa gctgaaaaga tcaagcatac
     7201 taagccaata ggtagactag catgcagaca ggccatggag atgatagttg ccgaaaagac
     7261 atggcgactg ggcatcgacc gtcccgaact atccttatca agaaggggac agatatccca
     7321 agtttcataa ggtctcgggt gattgatttt cttacgaaac agggacaagg ccacaaaacc
     7381 tgatgcagga ataagcacat aaaccccaac ttgctgacca agtcctagtt gcaggtaagt
     7441 ggtgactagc aagatcagat agaccagggg catggcgact gtcatcaaac gattgaaact
     7501 gcgtaatagg aataaaagaa ttggacgact agttagtctg gagctgatat ttcgatacca
     7561 ttcttgataa tttttcattt atgcttctca tacttttcta gaacttgttg agatgttttc
     7621 cccttggcaa gccaatccac tagcttgtcc aagcgacgta tttcctgcat cagaggatca
     7681 tcaatttcct caatacggac accgcaaatc ttccctgtaa ttgcaattcg ttcagggaca
     7741 taatatggtg cttgtctaaa aaaatctccg taagtaacat ccctatccag acaagcaaga
     7801 acatcactca cttcataccc tgtcaaccaa ctggtcactt ggtgaactga ctctgccttt
     7861 ccaccctttc gctcaacttt tgcaatcaag gctaagtaga cagcagcaaa tttcatattg
     7921 tataatttct gactcatact tctctctttc tatgtgtact agtataaata agaaaaagaa
     7981 ggccgtcaag ccttcttttg atttattctt ctgcttcatc ttctgtaaat tgactattgt
     8041 acaagtcagc gtagaagcca ccttgcgcca tcagttcctc atagttgcct tgctcgatga
     8101 tatttccatc tttcatgacc aagatcaagt ctgcatttcg gatggttgac aagcggtggg
     8161 caatgacaaa ggatgtgcgt ccttccatca aacggtccat ggctttttgg atcaattcct
     8221 ctgtccgtgt gtcaacagaa gaagtcgcct catccaaaat caaaagcggt gcatccttaa
     8281 gaagggcacg agcaatagtc aatagttgtt tttgtcctac agacaaggtc acggtgtcat
     8341 ccaagatggt atcatagcca tctggcaagg tcataataaa gtggtgaatt cccacagcct
     8401 tactagcttc catcattcgt tcatcactaa tccctatttg attatagatg agattgtctc
     8461 gaatagttcc ttcaaagagc caggtatcct gcaagaccat tgaaaaggca tcatgcactt
     8521 ctgaacgcgt catagccttg gtatccacac catcaatgtg aatacttccc ttatcaatct
     8581 catagaattt catcaaaaga ttgacaatgg ttgtcttacc agtcccagtc ggcccaacaa
     8641 tggcaacctt ttgaccagca tgagctgtcg cagagaagtc atagtcttga acattgacac
     8701 cgtccaccag aatttctcct gctgacacgt cgtagaaacg tggaatcaga ttgaccagag
     8761 ttgatttacc agaacctgtt gacccaataa aggccactgt ttgaccagtt tctgctttaa
     8821 agctaacatg ttcaataact gcctccgaat ttgccgcata gcggaaggtc acatccttaa
     8881 actcgacctg acctttgaag ttttcatcag tcagctgtac ttgaacaggg ttttggatag
     8941 aagaatgcaa atctaaaact tgattaatcc gcttagcaga gaccatagtt cggggaagaa
     9001 cgatgaagag tgctcccatg agaaggaagc ccatgacaac ctacatggca taagacatga
     9061 aaataatcat gtcactaaag agaggcagac gcgctatcgg agcagcgtcg ttaatcacat
     9121 aggccccaat ccagtaaatc gctacactca aaccacttga aatccccatc atgataggat
     9181 tcaaaatagc cataagacgg ttgacaaaca aattcaaacg ggtcaattca tcatttactg
     9241 ctgcaaattt ttcattttga taatcctctg cattgtaggc acgaacgaca cgaatacctg
     9301 ttaaactctc acgagtgata ctgttcagtt tatctgtcaa cccctgaatc aaggactgtt
     9361 ttggaaaggc tagcgtcatc aaaacggtcg tcatcaggac gttgacaatc actaccacaa
     9421 gtacggccca gagccagtat tctgaatgac ctaaaatctt cccaatagcc cagatagcca
     9481 taattgaacc acgcgttacc acttgcaagc ccatagtaat caacatttga acttgagtaa
     9541 tgtcattggt agtacgcgtc aagaggctag gaattgaaaa tttcttaatc tctgtctgcg
     9601 agtaatccaa aactcggtta aaaatatcac ttctcagcct actagtataa gaagccgcca
     9661 ctcgggatgc aaaaaatcca actgcaacta cggacaagaa ggcaagaaag gacattccca
     9721 tcatcatgct tgccggctgc cacaactcat ctaaattagt ttcttgacta cctagcaaat
     9781 ccgtaatttt cgagatatag gtcggcactt ccaactctag atagaccgaa aagcaagtaa
     9841 agagaatggc tagtaaaatc atccccattc ttttctacta attcttttgg ctaatttctt
     9901 tattctctcc tcctattccc ttgatatttg cctgtagttg accgagaact ttctcaaaaa
     9961 tcagtaattc atcttcatca atgtcttcca tcaactgctt gtctatgcgt tcaaaaaaag
    10021 ccttaacctg ttgcatctga gaacgtgctt tgtccgtcag acgaacaaac ttagcccgct
    10081 tatcaacagg actcgcctcc aattccacca aaccattttg cactatacgc ttaaccagat
    10141 tactagcaac agacttggta atattgagtt cctgctcgat atctttaatc aagaccaagt
    10201 cttggttttt ctcgcgatta tccaaaaaac gcacaacctg accttgcggc ccacccataa
    10261 attcaatgcc gcaacgtttg gcttcctttt gcaccatcag gtgaatttga tgaccaaaac
    10321 gcttaaagac taacatcggt ttacccataa tctccccctt ctaaataaaa atagttctct
    10381 ggagaataat taaatttcta tgagaactat tttcttgatt aaaaaaatcc caagtgattt
    10441 tctcacttag gatcatgttc tataggttaa attaaaaccc atctacgttc gtataaatct
    10501 tttggacgtc ttcgtcgtct tcaagaacgc tgtaaagttt ttcaaaggtt tcaaggtctt
    10561 cgcctgacaa ttccacttct gactgaggaa tcatttccaa ttcagtcact tggaattctt
    10621 caataccaga ctcacggagg gcaacgatag ccttgtgaag gtcagttggc gctgtgtaaa
    10681 ctgtgattgt accttcttgt gcttctacgt catccacatc cacatccgct tcgagcaatt
    10741 gctcaaagac tgcgtccgca tcttcacctc caaatacaat aacacctttg ttgtcaaaga
    10801 ggtaagaaac agaacctgaa gcgcccatgt ttccgccgtt tttaccaaag gctgcacgga
    10861 cattggctgc tgtacggttg acgttagaag tcaaagtatc cacaattagc atagagccat
    10921 ttggcccaaa accttcgtaa cgtccttctg taaaggtttc gtctgtgttt cctttggctt
    10981 tatcaatcgc tttatcgata atgtgttttg gcacttgggc ttgtttagca cggtcgataa
    11041 cgaatttcaa agctgagttt gattctggat ctggatcacc ttttttagct gctacataga
    11101 tttctacacc aaattttgca tatactttag agttagctcc atctttagcc gttttcttgg
    11161 ctacgatatt ggcccattta cgtcccatta ggaatctcct tttttcacat tttaatcttt
    11221 cttattataa cacaagtttt tttgattttc actagaggaa atggatttta ttagcaaatc
    11281 aagctaggat agcactttac ctgctaagac ggtcttgcct ttctatcttt atcaacagac
    11341 actcatccac attcaaaaaa caaactagac cattatctgc aaatagaaag tttcagccaa
    11401 gtttgacaaa gtcagctcaa attactgttt gaagtttgta gatataagcg acaaaaacaa
    11461 tcatactgca ccttttgttg acagtctact ccagacatat catagttcaa gtaaatactt
    11521 tgaaatccaa cagttcttat aggcgctatt gtattctaag aaatcaatag aagagtttct
    11581 aagcaaacct ctaatactca ataaaaatca aagaacaaac cagaaagcta gccgcaggtt
    11641 gctcaaaaca ctgttttgag gttgcggata gggctgacct ggtttgaaga gattttcgaa
    11701 gagtataatt tacgtgttcc caagatggag aagttagact agtacactgg cacttctaaa
    11761 ccattgctag caattgattt gttcatattt aatttcattt tttccataaa tgggtattag
    11821 atataaacag caaaatattt ccgatacgtg tcattcttga atttccaatc atctaaaaca
    11881 agtaaaggat aatcaatccc ctgtatatca aggaattggc tacccttttt acttttttac
    11941 acatcctgtt tgatagactc attttaacat cacgagcata ctccaatgga aatcgctagg
    12001 caagagataa actttcagat atccgcagag agatcatcgc ctctttttgt cgcaagcatt
    12061 ctcttctcct agtcattttc taccttatct tctacctgag gatagagagt tgttccccaa
    12121 atagaaatcg tccgcttacg cactagtggc aaatcggttt tttcataaac cgtacgccac
    12181 cattcccagg caagcccggt acactctcta attttgacag agagattacg aacattccct
    12241 tttaaaggaa tactagtggt aaagtgagcc gtcaaatcct gcccatttct gtcccaagcc
    12301 ttaggagtca agacttcctt accttgatga tcataggata attcatccca agtaatataa
    12361 tattgggcaa cataggcacc actatgatcc agcagtaaat ctccgtttct gtaagctgta
    12421 accttagtct caacatagtc tgtactgttt tgaaaggtcg caactacatt gtcacgtaaa
    12481 aaagaagttg tataggaaat cggcaagcct ggatgatctg ctgtaaagcg actgccttct
    12541 tgaatcaagt cctctaccat atccaccttg cctgttacaa ctcgggcacc cgaacttggg
    12601 tcgcccccta aaataaccgc cttcacttct gtattgtcca aaatctgctt ccactctgtc
    12661 tgaggagcta ccttgactcc tttcatcaaa gcttcaaaag cagcctctac ttcatcactc
    12721 ttactcgtgg tttccaactt gagatagact tggcgcccat aagcaacact cgaaatatag
    12781 accaaaggac gctctgcaga aattcctctc tgttttaaat cctctaccgt tacagtatct
    12841 tgaaacacat ctcctggatt tttaacagcg tctacgctga ctgtataata aatctgctta
    12901 aaattaacaa tctgaatctg cttttcacct gaatggacag agttaaaatc aatatcaaga
    12961 gaattccctg tcttttcaaa gtcagaacca aacttgacct tgagttgttc catgctgtga
    13021 gccgttattt tttcatactg cattctagct gggacattat tgacctgacc ataatcttga
    13081 tgccacttag ccaacaaatc gtttaccgct ccgcgaacac ttgaattgct ggggtcttcc
    13141 acttggagaa agctatcgct acttgccaaa ccaggcaaat caatactata agtcatcgga
    13201 gcacgatcaa ccgcaagaag agtgggatta ttctctaaca aggtctcatc cactacgaga
    13261 agtgctccag gatagaggcg actgtcgttg gtagctgtta cagaaatatc acttgtattt
    13321 gtcgacaagc tccgcttctt tctttcgata acaacaaact catcgggtag ctgattaccc
    13381 tctttgatga aacgattttc aatactttct ccctgatggg tcaagagttt ctttttatcg
    13441 taattcatag ctagtataaa gtcatttact gctttatttg acatcttcta cctcctaata
    13501 agttcctgga ttgagttgca taaactcaga cttgttcagc gaaatcagcc gtggttggac
    13561 taagtgatcc aaaatttcct cgtacaattc ttctgagaca ttgcgtcgcc gtctggctag
    13621 ataagaagtc ggaataaccg tattatccaa cataaatacc ttatctaagt caatcaaggt
    13681 tggtcttgta aaaggattac gagctagatc cggctcttct atcataaagt tcttgaccaa
    13741 acgtctggtc aagagagctg gtttgaaggt ctgattttta accaactctt tgtttttagt
    13801 catgctgttg tcaatacaga tatacatatg attcttcaca gccaaatcgc tactaatagt
    13861 cggaaaaggc aaataaagag ctacaacatc tcctctctta atcaagcaag agcaccccct
    13921 tttctcctaa tgtaacatag acaggattga ccaagtcttc tgattgactc agaatttcca
    13981 aagtttgagt ttggcgcgct gtcaatttag tagcatcttg tctcttcaat acaaaatgct
    14041 tgtcgccaat aaccttgaca atataatcct tctccaaagc tgactggtaa atccacatca
    14101 gatgttgtct gtcctgagaa ctcaagagag aaggattttc aagcctcccg atagtctgat
    14161 aaaaatcaaa aacaggagct aactcctgcc aatctgattg gctagttgtc aaggctagaa
    14221 aaagggcttt gcgagctgat acttcttggt tagccttgag agttactttc ccctccaagt
    14281 tttttagaaa tcgggaaact ccagaaagca aatttttctc taactgcgag aaataaaaac
    14341 ctttcgttcc cagacataag tctttcatgt cgctttctct agcaaataag agctcaaaca
    14401 tttgatagta aaagaaaaat atctggcact gggtcgcgct catcttttcc ttatcggctt
    14461 ctttttttaa ccagagcaag ggcgacagat aactggattg agacatttcc tctacctcct
    14521 actctttttt aactggagca tctgcactag ctgccacttc ttttgactgg atactttccc
    14581 actggttaat ctcctctgag ataagacctt cgcatgtctt gacaaatagg gcaaaagcct
    14641 tggtctttcc tgcatatttc tccgtttggc attgatagag gaatttttct ttctccagga
    14701 gttgcgcagt tttttggtaa gaaatccaat tttcctttgc attatacaaa ttgataatcc
    14761 cctcacacag caagccgaga ctggataagg caaccgaaat caaacggtag cgatcacctg
    14821 gcataggaat agcacaaaag acagctatga ggaaacctgc cacgatttct gttattttta
    14881 ataccttata gcgcctacga tgttgaacgc ttttctttaa aaaatgagct atctgtacgt
    14941 ctaatcgctc tgtcaggtac atttcttctg gcgtcatatt cgtaactcct ttcatttact
    15001 ttgataacca tagtataaca tatttgaata tcaaagtata gtaaaaactg gactataact
    15061 tattagactt cctgcgaaac aaaatatggt atagtagttc tatgaattat gaagcaagta
    15121 aacaactaac tgatgcacga tttaagcgtc ttgttagtgt tcagcgtacc acttttaaag
    15181 agatgttagc tgtattaaaa acagcttatc aaaaaagtcg gacaagctgg taaaatcttg
    15241 gctgacagtg gttatcaagg gctcatgaag atatatcctc aagcacaaat tccacgtaaa
    15301 tccagcaaac tcaagccgct aacagttgaa gataaagcct gtaaccatgc gctatctaag
    15361 gagagaagca aggttgagaa catctttgtc aaagtaaaaa cgtttaaaat gttttcaaca
    15421 acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgattgc tggtattatc
    15481 aatcataaac taggattcta gttttgcagg aagtctatta taaaaattga agaaattaaa
    15541 aagagatgat attagggaga actgatttaa aagttctccc tatttaacat tattaaataa
    15601 aacctaatta tatagtaaac tgaaataaga tataaacaaa tgaattggag cttaacatcc
    15661 attttaagct aattttttag aaactacagt gtactactct ggattcaaca cattataatt
    15721 gaaattgaag gttagattta aagtaataaa gaataatatt acgctctaaa attagataaa
    15781 tttcaaataa ttcaaataat taaggatacc tatcactatt ataaagtaac tgaacaacat
    15841 tttatattta acaattattt aaaataataa aataataaaa taataaaatt ataacattat
    15901 ataaattatt ttaaaaaata atgaaacgtt ccaacttatc tattgacacg ttccaagaaa
    15961 tcggatacaa tgtaattaac aataaagata ggagaaaata atttgaatcc attaaaagaa
    16021 tgctatgaaa aaaacggtat actaattgca gcacaccgtg gtacaaacgg aggaaatata
    16081 ttacaaaaca catcaaaagc ctatttgaat tccatacgcc ataacgcaga tatgtttgag
    16141 gttgatgtaa ttcgttcaaa agatggagaa ttttttgcat ttcacgatgg gcaagaacct
    16201 ttagtatttg gtaaaaaaat tgatattaga actttgagtt ctgaagagat ccaaagaaag
    16261 gaatgtttta attcactgaa tgaacccata ttacaaaaga ttgaaaaaat ttctgatgta
    16321 ttaaaaaatt ttgagggaca atctttaata aatatagata gaagttggtt ttactgggat
    16381 accttcctag ataagttaaa aacatatcca tctttgaatc aagttctttt aaaatcacct
    16441 gtaaaaaaag aattattgga aatgcttaga gactctggtt tgaatgttat gtatatgcca
    16501 attatcaaaa caattgaaga gttagatttt gttctctcat ttgaaggaat aaatacagta
    16561 gctgtcgaac ttgtattcca agatttagaa aatccaatca taagtaagaa aataattgat
    16621 gatttacatg aaaaaggatt acttatttgg gttaatgctt taaccttaag tgattcaatt
    16681 attctttcgg ctaagattga tgatgataca gctattgctc atgatggcga atcttggggg
    16741 aaattggttt caataggatt tgatattatt caaacagatt ggccattatt actttatcaa
    16801 tatctagttg aaaaaaataa aaaaataaaa ataaaggaga actatcatgt tcaaaaactt
    16861 taaaaagatt gcattcactt cttcactaat tttacttgct gcttgctcaa acaatgcttc
    16921 aaatacaaat cagtctactg atgaaggaag tgttgataaa tctcaagaaa ttgtaatcta
    16981 tacaaattcg gcttctaatg gacgtgcaga ttggttacaa actaaagcat cagagcaagg
    17041 atacaatctt cgtttggtag atatttcagg tggagaacta gctgaccgtt tgattgcaga
    17101 aaagaataat gctgtggctg atatggtaat tggattaaat aaattagaat ttaaccgtat
    17161 taaagctgaa aaacttcttg taaaatactc accaaaatgg gctgatgaag tagatagctc
    17221 tttgggagat tctgaagggt attattcacc aattgtaaat caaccattag ttttgattgg
    17281 taataaagat gctaaaatgc catccgactg gacagatttt actgattcat cttataaagg
    17341 taaatatggt atttcaaaat taagtacagg tacatctaag aacatctttg caagtattgt
    17401 ttcgagatat aaagatgaaa aaggtgagtt aggaatatct gatgaaggtt ggaaagttgc
    17461 aaaagcttac cttaaaaatg cacacgttta tgcagaaggt gaagactata tctcttcaat
    17521 tatggataat aataatgatc taaaatatag tatgatgtgg ggatctggtg ttctacaaaa
    17581 tcaaaaagaa cgtgaatata aattccaagt aatgtcacca aaagttggtg ttccttatgt
    17641 aactgaacaa gttgggattt taaatacaag taagaagcaa gcattattaa aagaatttgt
    17701 agattggttt ggctcttcag aacttcaaaa agaatggtct gataaatttg gttcaattcc
    17761 agctaataaa aaagctctag agcaagcaaa agatgaactc aaacagtttg ctaatagtgt
    17821 taaaccacaa gaacttgact gggagtttat cgggaaaaac atcgattctt ggattgaaaa
    17881 agcacagctt gaatttgttg aacagtaata gttaggatta agtgatgatt acatttaagg
    17941 atattcaaat taagtataat gattttattg ccatcgataa tctcaattta acaatcaatg
    18001 agggagagtt tttcacattt ttaggaccaa gtggttgtgg gaaatcaaca actcttcgtg
    18061 cactagttgg atttttggag ccttcacagg ggcaaatact agttgataat caagatatta
    18121 cgaatttaga tccggaaaaa cgcgaaattg gtattgtgtt tcaaagttat gcattattcc
    18181 caacaatgac tgtttttgat aatattgctt ttggtctaaa agttaaaaaa gtttctcctg
    18241 aaattattaa agctaaagtt catgaaattg cgaaaaaaat taatatctca gacgagcaac
    18301 taaaccgaaa tatttctgaa ttatcagggg gacaacaaca gcgtgtagct ttagcacgtg
    18361 cattagtatt agaaccaaaa attctttgtt tggatgaacc gttatcaaac ctagatgcca
    18421 aactacgagt ttcgttgaga aaagaattga aacgattgca aaaagaacta ggaatcacta
    18481 ctctttatgt cacacatgat caagaagaag cattaacatt atcagatagg attgctgtgt
    18541 ttaataatgg atttattgag caagttggca cgccgtatga tatttataat caatccgcaa
    18601 ctcaatttgt ctgtgatttt attggctcaa tcaataaaat tagccaagaa gttcttaaaa
    18661 aattacaagg cgagaataaa tactttaaag aaactgaagg atacatacgc ttagagcgtg
    18721 ttaagttaga gaaaacttca cctcaagatt tatctataac aggggtaatt agtgatattg
    18781 agtttaatgg tgtacttatt aagtataaag tagacttgtc gaatagtgaa agtattcata
    18841 ttatcgaaaa gaatgatgga ctatcacgtc atataatcaa agaaaaagtc actatgtaca
    18901 ttaatccgcg tgatataatg caattttaag gagattgtgc atgagaaaga gtctaaactg
    18961 gaaagattgt ctcataagat taggagtttt atggctaatc tttgccctga ttatttatcc
    19021 aaatattgaa cttttgtctg gagtgtttta taaaaatggt tcatttactc tagaggcatt
    19081 caataagatt atacactctc agagagcgat gagtagtata tttaatagct ttattttggc
    19141 gatttcaatg gtctttactg taaatattgt tgggacattg attgttctac tcacagagta
    19201 ctgggatatt aggggttcaa aaatacttaa attaggttat atgagctctc tagtatatgg
    19261 aggaattgta ttagcgacag gatataaatt tgtttatggc gctaatggtc ttgtaactaa
    19321 aacgctctca agtataattc caggtcttgc ccctaactgg tttcaaggat ttggtgcagt
    19381 attgtttatt atgacatttg cttgtacctc aaatcacata atgtttttaa caaatgcagt
    19441 tcgtagtgtt gattatcata caattgaggc agctaaaaat atgggtgcaa gtcctttaaa
    19501 agttttcttt agtgtggttt ttccaacttt taaacctacg ttatttgcct taaccatctt
    19561 aacttttttg acaggtcttt cagcagtttc tgctcctttg atagtagggg ggaaagattt
    19621 tcaaactatt aacccattga ttatcagttt cgctaaaact acaagttcga gagatttagc
    19681 agctttacta gctatcatgt taggtttagc aactattcta ttattgacac ttttgaatca
    19741 tgtcgaaaaa ggaggtaatt atgtatctgt ttcgaaaacc aaggctagta ttaagaagca
    19801 gataatttct tctccattat ggaatactct tgctcacatt gttgcgtatg tattgtttgc
    19861 aatctatatg ttaccaatag ttttgataat tctatactcg tttacagact cgttgacgat
    19921 caagacggga actttagatc tatctaaatt tacgttagcg aactatgcta atttatttac
    19981 agatgctcaa tcatttcgtc cttacctagt cagcgttgtt tatgcaattt tagctgcggt
    20041 aattgctaca attatagcaa tagtaatttc acgtattgta cataaaaaca agagtaagtt
    20101 cgataaattc tttgagtatg gtgcactgat accatggata ttgccaggta cattgattgc
    20161 actaggatta atgttcactt ataatatacc tcatttaata ctatttaatt tagttttagt
    20221 aggaacagta attattttac ttattgcata tactattcaa aaattaccat tttcttatag
    20281 aatgattcgg gctgtatttt tcagtataga taatgatatg gaagaagctg cacgtagtat
    20341 gggtgcatct agtttctaca ctatggtgcg agttattata ccgtatattt taccagtcgt
    20401 attatcagta gttgtgttaa actttaattc tttattatct gactatgact tatctgtatt
    20461 cttgtaccat ccacttttcc aaccattggg aatcgttatt aaacagtcta ctgatgaaac
    20521 agcaacttta aatgcacagg caatgatgtt tgtttattct gtaattttaa tgattatgtc
    20581 tagtgcagct ctttatttat caagcctatt ccaaggtaaa cgaggtaaga gataatatga
    20641 atctttcata cgaactgagt atttgggaaa tacttcttag gtgcttttta gcgattcttt
    20701 tcggtggcat tgttggctat gagcgaggag tcaaaaacca agcagcaggg attagaacct
    20761 acttactagt ttgtttggga acttgtgttg taatgatgac aaatcagttc atcactagtc
    20821 gttatggtag cggtgatcct agtcgaatgg gagcccaagt aattagtggc ttgggtttcc
    20881 taggggcagg aacaatcatg gtaactaatc aaaaagttaa aggtttaaca acagcagctg
    20941 gattatggtc ttcagcaact attggtttag ctataggcat tggtttttat gaaggtgcta
    21001 ttttagccgg agttgtactc atagcagttt taactctatt tactcctctt aaagattatt
    21061 taaactcgaa aactaaaatt gctgattact acttggtttt tagttcttta gaaggttata
    21121 atcgtttact tatatattta aatacatcgg gtattaagat tttagaaatt caaaatggta
    21181 taggaaatct tgatgaagaa cgtcaattaa ataaaattaa gtcaacaaaa gtgtcctgct
    21241 atttatcatt aaaattaaac gaaaactttg aacatttaaa attaatggaa gaaatgcata
    21301 atattgctgg tgttatttat gttgaagaga ttaggtaagg gtgactttgt ctaatttttt
    21361 ctatatttct aatcggagaa aaaaatgaat ataatttttg atttagggaa tgtgttgatt
    21421 gaatggaata aagaaaaaat tttatcaaaa atctgtaaga atgatttaga atataattta
    21481 tttaataagt ttgtatttca atctaacttg tggattgatt tggataatgg taaaattagt
    21541 ttagagttct tagagaatca attaatcgat gaaatgggac atcaatatca ggatcaaatt
    21601 catgagttag tatggaattg gtttaactat gttgatttat atgatgaagt ttatgaatta
    21661 ataaaacagc taaagaaaaa gaattttcaa atttatgttt tatcaaatac ctcctcaatt
    21721 tttcatattt tattagattc tgttctatct aaagtatcat ctgttttaga tggttacgta
    21781 atttcttgtg aagttaaaat gatgaaacca caaaaagaaa tttacttgtc attagttaat
    21841 aaatatcaat tagatataaa agattgtata tttttagatg atttagaaga aaatgtagaa
    21901 gctgcaagaa ctctaggtat taaagcattt caaattaaag agcgtaaaga gatctcaaat
    21961 atactaaaag atctcttaaa ctagaggtta attatggtta caataaaaga tattgcaaga
    22021 gtgtctggag tctcacatgg gacagtttca aacgttttaa ataaaaaagg taatgtctca
    22081 gcagctaaaa taaagttagt agaagagact gcgaaaaaat tgggttataa tatgaattct
    22141 caagctcagt ttcttcgaaa aggcgcttct agtaaatgtt ttttcttgtt atttaataat
    22201 gcacgcaaaa agtatgctga gtattttgca gaaattgatc agttatcttt agatgtagaa
    22261 tatgtttact tacataaatt ctcagagatt aaaaataaga tatctgcaat tttaagtgaa
    22321 aatcctcaat ttatagtttg cttaggtttt tctccaaaaa gattcgttga tattgaagat
    22381 aatattccga tttttgaagt agatacatat caatctaata aaactttatc ttcctttgat
    22441 agtgataaaa tatttgagat tgtacttgag ttggttcgga ctgaaaagct atctaattta
    22501 tattttattt cacttactaa tgaaaaagaa cattctttat ttgaatattt gactcaaaaa
    22561 ataaaaaact caactcatat acaagtgcaa gaacgtttac aattgttgtc tctatatcct
    22621 actctaaaaa actttgcaaa gtatgattgt atatttgttg atgatgaaga tttgatgcac
    22681 acgctattag acttatttga ttggtttact ataattgata gaccaaaaat atgtttgata
    22741 ggttcacgtg tttggttcga aaaaagaaat cttttttata tacatttaga ttatagaata
    22801 ttggcactca atactgccga aaatttagaa agtggaaata gttcaattgt accagttaaa
    22861 gatggcaaac aaattttaac taatcaatta tttgatggag aatgtgatga tatttattta
    22921 cttactgtcc attcaccaat gaataaagcc ttagaaattt tatcagaaaa gtataaacaa
    22981 atttctggga aaaatattaa aattatcgag aaaagatatg atgaactttt ggagatgatt
    23041 gagtctggcg atgtttcatc cagttttgat atgattagaa tggatatggc ttggcttcca
    23101 acatttggga aaaagtattt tcaagagatt acaagcttta gacaaacaaa aagtattaat
    23161 caaaatattt ctaagtcggt gtctcgagag tatatgtata ttgatcagaa gcaatatact
    23221 tttccattgg atgttagtag tcagatttta gtatatagaa aagacttatt tgaagattca
    23281 tttttacaaa gacgatactt tgaaaaaaca aaaagaaaat taactgtacc aaaaagttat
    23341 caagagtttg atgagttaag tgaatttttt acattaacag aaaatccatt ttcacctaca
    23401 ctttatggcc atagtttagc tttaagttct tcagtgagag cagcatgtga atttattcct
    23461 cggtttcgtg agagattagc acaatctaga atgaatcttg ctgtacttcc tcaggtttta
    23521 actgagtatg agaaaagtta tcagtttacc gaaaaatcat ttaattcttc gtggaacgat
    23581 ttcgttacga acttaaacag tggtaaaact tcaatggaaa taattttttc aaattatact
    23641 agtccattat ttgatggtct caatgtttct gctcagtttg agtttgcaac tgccactata
    23701 cctggtaata ctcctgtgat aggtggtggc tcaattggaa tttctaaata ttcaaataga
    23761 gtggaagaat gtctaaactt tattaattgg ttatattctg aagagatttc tattttacta
    23821 acatctctgg gtggtttttt accatcaaag tatgtcatgc aaaataggat gttacaattt
    23881 caatacccat ggttatctag tttagaagat acatttagta ttgggagtag aacaaaatgg
    23941 tacggcttta atactgattt tagatttgag cagatgttag ggcaagagtt aatagaaagt
    24001 gtgaagcata gatatggata aattaatact aaatttttat tactagttta tttattattg
    24061 tttaaaatta aagattcaag taaacaccaa ttatatttaa aattattatt ttgacatttt
    24121 tctattgcaa agttatttta ttagactt
//
LOCUS       DBEJZV010000027        23134 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.27, whole genome shotgun sequence.
ACCESSION   DBEJZV010000027 DBEJZV010000000
VERSION     DBEJZV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.27"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..456
                     /locus_tag="ACL3S0_001505"
     CDS             <1..456
                     /locus_tag="ACL3S0_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312396.1"
                     /translation="DSWYYLNASGAMATGWLQYNDSWYYLNASGAMATGWLQYNGSWY
                     YLNANGSMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDT
                     WYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWV"
     gene            857..1978
                     /gene="mnmA"
                     /locus_tag="ACL3S0_001506"
     CDS             857..1978
                     /gene="mnmA"
                     /locus_tag="ACL3S0_001506"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGR1312397.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2119..2574
                     /locus_tag="ACL3S0_001507"
     CDS             2119..2574
                     /locus_tag="ACL3S0_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR1312398.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWKGQLRHIHLEK"
     gene            2584..4497
                     /gene="mnmG"
                     /locus_tag="ACL3S0_001508"
     CDS             2584..4497
                     /gene="mnmG"
                     /locus_tag="ACL3S0_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGR1312399.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4876..6555)
                     /locus_tag="ACL3S0_001509"
     CDS             complement(4876..6555)
                     /locus_tag="ACL3S0_001509"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR1312400.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQGEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6557..6790)
                     /locus_tag="ACL3S0_001510"
     CDS             complement(6557..6790)
                     /locus_tag="ACL3S0_001510"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGR1312401.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7070..7283
                     /locus_tag="ACL3S0_001511"
                     /pseudo
     CDS             7070..7283
                     /locus_tag="ACL3S0_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7606..7758)
                     /gene="cibB"
                     /locus_tag="ACL3S0_001512"
     CDS             complement(7606..7758)
                     /gene="cibB"
                     /locus_tag="ACL3S0_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGR1312402.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7760..7945)
                     /gene="cibA"
                     /locus_tag="ACL3S0_001513"
     CDS             complement(7760..7945)
                     /gene="cibA"
                     /locus_tag="ACL3S0_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGR1312403.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8123..8806
                     /gene="tsaB"
                     /locus_tag="ACL3S0_001514"
     CDS             8123..8806
                     /gene="tsaB"
                     /locus_tag="ACL3S0_001514"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGR1312404.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKNLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYVGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8803..9240
                     /gene="rimI"
                     /locus_tag="ACL3S0_001515"
     CDS             8803..9240
                     /gene="rimI"
                     /locus_tag="ACL3S0_001515"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGR1312405.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVIAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9230..10240
                     /gene="tsaD"
                     /locus_tag="ACL3S0_001516"
     CDS             9230..10240
                     /gene="tsaD"
                     /locus_tag="ACL3S0_001516"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGR1312406.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10280..11586)
                     /locus_tag="ACL3S0_001517"
                     /pseudo
     CDS             complement(10280..11586)
                     /locus_tag="ACL3S0_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11922..12613)
                     /locus_tag="ACL3S0_001518"
                     /pseudo
     CDS             complement(11922..12613)
                     /locus_tag="ACL3S0_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12856..13176
                     /locus_tag="ACL3S0_001519"
     CDS             12856..13176
                     /locus_tag="ACL3S0_001519"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312407.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMFLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKI"
     gene            13219..13410
                     /locus_tag="ACL3S0_001520"
     CDS             13219..13410
                     /locus_tag="ACL3S0_001520"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR1312408.1"
                     /translation="MLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWTYSMGD
                     AFICVSETMKKRLESIIKK"
     gene            13538..14062
                     /locus_tag="ACL3S0_001521"
     CDS             13538..14062
                     /locus_tag="ACL3S0_001521"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR1312409.1"
                     /translation="MDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICH
                     LKCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNIGGLS
                     EIIEHRVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVET
                     MRVYDELLEKSSHG"
     gene            14055..15008
                     /locus_tag="ACL3S0_001522"
     CDS             14055..15008
                     /locus_tag="ACL3S0_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR1312410.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFPFLEYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            15018..16634
                     /locus_tag="ACL3S0_001523"
     CDS             15018..16634
                     /locus_tag="ACL3S0_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1312411.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKRIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16894..17322
                     /locus_tag="ACL3S0_001524"
     CDS             16894..17322
                     /locus_tag="ACL3S0_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312412.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            17334..18083
                     /locus_tag="ACL3S0_001525"
     CDS             17334..18083
                     /locus_tag="ACL3S0_001525"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGR1312413.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCSDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            18096..19268
                     /locus_tag="ACL3S0_001526"
     CDS             18096..19268
                     /locus_tag="ACL3S0_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGR1312414.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPFGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNLSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            19664..20527
                     /locus_tag="ACL3S0_001527"
     CDS             19664..20527
                     /locus_tag="ACL3S0_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR1312415.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            20813..21013
                     /locus_tag="ACL3S0_001528"
     CDS             20813..21013
                     /locus_tag="ACL3S0_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HGR1312416.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            21080..21745
                     /locus_tag="ACL3S0_001529"
     CDS             21080..21745
                     /locus_tag="ACL3S0_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR1312417.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            21817..23043
                     /locus_tag="ACL3S0_001530"
     CDS             21817..23043
                     /locus_tag="ACL3S0_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR1312418.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         7083 a         3944 c         4930 g         7177 t
ORIGIN      
        1 gattcatggt attacctaaa cgctagcggc gctatggcaa caggttggct ccaatacaac
       61 gattcatggt attacctaaa cgctagcggc gctatggcaa caggttggct ccaatacaac
      121 ggttcatggt actacctcaa cgctaacggt tcaatggcaa caggttggct ccaatacaac
      181 ggttcatggt actacctcaa cgctaacggc gctatggcaa caggttgggc taaagtcaac
      241 ggttcatggt actacctcaa cgctaacggt tcaatggcaa caggttgggt gaaagatgga
      301 gatacctggt actatcttga agcatcaggt gctatgaaag caagccaatg gttcaaagta
      361 tcagataaat ggtactatgt caatggttta ggtgcccttg cagtcaacac aactgtagat
      421 ggctataaag tcaatgccaa tggtgaatgg gtttaagccg attaaattaa atcatgttaa
      481 gaacatttga cattttaatt ttgaaacaaa gataaggttc gattgaataa atttatgttc
      541 gtattcttta ggtacctatc ttatgatttc aggaaatgtc attaaaaaaa cgactccttt
      601 tctctaactt gaaaaataga ttagagaaaa tgggttgttt tatttattat agttatttga
      661 atgaagataa gaagaaggta tactcacatc attcacataa tctgtatatt gactataagt
      721 tttaaaaaac aatttttaag ctcttccttg tcttctctaa ccaagcgtgt tataatgaat
      781 actgctcaag cgaccttcaa tcgtgaagca cacacgacct tcaatcgtga ataaacgaat
      841 agatgggaga cttaccatga gtgataactc taaaacacgt gttgtcgtgg ggatgagtgg
      901 tggtgttgat tcgtcggtga cggctctttt gcttaaggag cagggctacg atgtgatcgg
      961 tatcttcatg aagaactggg atgacacaga tgaaaacggc gtttgtacgg cgaccgaaga
     1021 ttacaaggat gtggttgcgg tggcagacca gattggcatt ccctactact ctgtcaattt
     1081 tgaaaaagag tactgggacc gcgtttttga gtatttccta gcggaatacc gtgcagggcg
     1141 cacgccaaat ccggacgtta tgtgcaacaa ggaaatcaag ttcaaggcct ttttggacta
     1201 tgccatgacc ttgggggcag actatgtagc gactgggcat tatgctcgag tggcgcgtga
     1261 tgaggacggc actgttcaca tgcttcgtgg cgtggacaat ggcaaggacc agacctattt
     1321 cctcagccaa ctttcgcaag aacaactcca aaaaaccatg ttccctctgg gacatttgga
     1381 aaagcctgaa gtacgcagac tagcagaaga agcaggcctt tcgactgcta agaagaaaga
     1441 ctcgacaggg atttgcttta tcggagaaaa gaactttaaa aactttctca gcaactacct
     1501 gccagctcag cctggtcgta tgatgactgt ggatggtcgc gatatgggcg agcatgctgg
     1561 tctgatgtac tatacaatcg gtcagcgtgg cggactcggt atcggtgggc aacacggcgg
     1621 tgacaatgcc ccttggttcg ttgttggaaa agatctaagc aagaatattc tctatgtagg
     1681 acaaggattc taccatgatt cgctcatgtc aactagccta gaagccagtc aagtccactt
     1741 tactcgtgaa atgccagaag agtttacgct agaatgtacg gctaaattcc gttaccgtca
     1801 gcctgactct aaggtgaccg tccatgtcaa aggagacaag gcagaagtta tctttgcgga
     1861 accacaacgc gcgattacac caggacaggc agttgtcttt tacgatggcg aagagtgtct
     1921 aggtggcggt ttgattgaca atgcttaccg cgatggacaa gtttgtcagt acatttagat
     1981 tgacaaattt tctcaatttg ctacaataat aacagcaata gaaatgatgg tcaaagctca
     2041 tggatgttgc aggctttttt gtcctgcact tctttgtagt tttgactgtt tttgtgtcgt
     2101 ttaagggaaa ggacaagaat gactcaacaa gactttcgga caaaagtaga caatacggtt
     2161 tttggtgttc gggctacagc cttgattgtc caaaatcaca agcttctagt taccaaagac
     2221 aagggcaagt attacactat tggaggtgcg attcaagtca atgaaagcac ggaagacgcg
     2281 gtagtccgtg aagtgaagga agaactgggt gtcaaagctc aagctgggca gctagctttt
     2341 gtggttgaaa atcgttttga acaggacggt gtttcctatc acaatatcga atttcattat
     2401 ctggtagact tactggagga tgccccattg accatgcagg aagatgagaa aaggcagccc
     2461 tgtgagtgga ttgacttgga taagcttgag gatatccagc tagttccagc ctttttaaaa
     2521 acggccctac cagattggaa aggccaacta agacacatcc atcttgagaa ataggagaga
     2581 aatatgacat atcattttac tgaagaatac gatattattg taattggtgc gggacacgct
     2641 ggggttgagg cttccttggc cgctagccgt atgggctgta aggtcctgct tgcgaccatc
     2701 aatattgaaa tgctggcttt catgccttgt aatccctcta tcggtggttc tgctaagggg
     2761 attgtcgtac gtgaagtcga tgccctcggt ggcgagatgg ccaagaccat tgacaagact
     2821 tacatccaga tgaagatgct caacacaggg aaggggccag ccgttcgtgc ccttcgtgcg
     2881 caggctgaca aggaacttta ctctaaggaa atgcgcaaga cagttgaaaa ccaagaaaat
     2941 ctgacccttc gtcaaaccat gattgatgag attttggtgg aagatggcaa ggttgtcggt
     3001 gtgcgtacag ccacccatca agaatatgct gctaaggctg ttattgtgac gacagggact
     3061 gctctccgtg gggaaattat catcggagac ctcaagtact catcaggtcc taaccacagc
     3121 ttggcttcta ttaacctagc tgataatctc aaggaactgg gcctcgaaat cggtcgtttc
     3181 aagacaggaa cccctccacg tgtcaaggct tcttctatca actacgacgt gacagaaatc
     3241 caaccaggag atgaagcgcc taatcacttc tcatacactt cacgtgatga ggattatgtc
     3301 aaggaccaag tgccatgctg gttgacctac accaatggta ccagtcatga gattatccaa
     3361 aacaacctcc accgtgcgcc tatgtttaca ggtgtggtca agggagtggg gcctcgttac
     3421 tgtccgtcga ttgaagacaa gattgtgcgc tttgcggaca aggaacgtca ccaactcttc
     3481 cttgaaccag aagggcgcaa tactgaggaa gtctatgtgc aaggactttc aaccagtctg
     3541 cctgaggatg tccagcgtga cttggttcat tccatcaaag gtttggaaaa tgcagagatg
     3601 atgcggacag gttatgctat tgagtatgat atggtcttgc ctcatcagtt gcgtgcgact
     3661 ctggaaacca agaaaatctc aggtctcttc actgctggtc agacaaatgg aacgtcaggt
     3721 tacgaagagg cagcaggcca agggattatc gcgggtatca atgcggctct gaaaatccaa
     3781 ggtaagcctg agttgatttt gaagcgaagt gacggttata tcggggtgat gatcgacgac
     3841 ttggtgacca agggaaccat tgaaccttac cgtctcttga ccagtcgtgc tgaatatcgt
     3901 ctcattcttc gccatgacaa tgctgatatg cgcttgactg agatgggacg cgagattggc
     3961 cttgtggatg atgaacgctg ggctcgtttt gaaatcaaga aaaatcaatt tgataatgag
     4021 atgaaacgcc tagacagtat caaactcaag ccagtcaagg aaaccaatgc taaggttgag
     4081 gaaatgggct tcaagccctt gacagatgcg gtgacagcca aggaattcct tcgccgtcca
     4141 gaagtttctt accaagatgt ggtggccttc atcggaccag ctgcagaaga cttggatgac
     4201 aagattatcg aattgattga aacagaaatc aagtacgaag gctatatttc aaaagccatg
     4261 gatcaggttg ccaagatgaa acgtatggaa gaaaaacgca ttccagccaa tattgactgg
     4321 gatgacattg actctatcgc aacagaagct cgtcagaagt tcaaactcat caatccagaa
     4381 accatcggcc aagccagccg tatttcggga gtaaacccag cagatatttc tattttgatg
     4441 gtgtatctgg aaggtaaaaa tcgtagtatt tctaaaactc ttcaaaaatc aaaatgatac
     4501 gtcgttggct tcttacgaat gagttcaaag cttggctttg attcatctcc agcctcccat
     4561 agtttcccga actatgggag ctaactcaag ttatgcattt tcctagcctt ctggtctgat
     4621 tttcattgag ttttaatctc aaaagaaagc atagagaaaa acagctccga agacggggct
     4681 gttttgttga cttgtactca atgaaaatca aagagcaaac taggaagcta gccgtaggtt
     4741 gctcaaagca ctgctttgag gttgtagata gaactgacga agtcagctca aaacacagtt
     4801 ttgaggttgt ggatagaatt gacgaagtca gtaacatata tacggcaagg cgaagctgac
     4861 gtggtttgaa gagtattatt cttcatctgg tgtgaggatc atcgggatga tgatcggttc
     4921 acgttcggta ttttcataga ggaaggggcg aatagcgttg acaatggcac cattgacaga
     4981 ttgcacgcta gcatccttat ttttcagtgc gatacgaatg gcattgaaga ggatacgctg
     5041 gctttggcga atcaagtcgc cagactctct catgtagaca aagcctcggc tgaggatgtc
     5101 tggaccagat agaatcatct gcgatttgaa gtcaacagtt gcgactgcca gaacgacacc
     5161 gtcttcagat agatcgcgac gatctttgag gacagctgcg ccaatttcac cgatacgatt
     5221 tccatcgaca tagatatctt gggcgttgaa atgacctgcg atacgagctg agtcagcagt
     5281 aagggcaagc acatcgccat tgctcatgat aaagatattg tccttctcaa caccagtatc
     5341 cactgctagt ccagcgtgga ctttttgcat gcggtattca ccgtggacag gcatgaagta
     5401 ttttggctta atcaagcaga gcatgagttt ttgctcttgc tgaccaccgt gtccagatgt
     5461 atggatattg ttcactttac cgtggataac ttcgacacca gcttcagaaa tgatgttaat
     5521 cagcttgttg acgctagtag tgtttccagg gatgggacta gaagagaaga taacggtatc
     5581 acctggttgt aattgtactt gacggtgggt tccgttggcg atacgagaga gggctgccat
     5641 aggctcaccc tgactacctg tacagaggat aagaacttct cctgcaggat aatctttgat
     5701 ttcatttggc tcgataaagg ttcccttagg agctttgata tagccaagat cgattccgtt
     5761 gacaatggcc ttttccatag aacgaccaaa gaccgcaatc ttgcgtccag tcttaacagc
     5821 agcttctgtt gcctgctgga gacggaagat atttgaggca aaggatgcaa agatgatacg
     5881 tccttcaata ccttggataa tcttcataat ggactgacca acgacttttt cagagttggt
     5941 aaaggttggt acttccgcat ttgtcgagtc agacaggaga cagagcacgc cttcttcacc
     6001 aagcgcagcc atacgatgca agtccgcagg ttctccaact ggagtaaagt cgaacttaaa
     6061 gtcacccgta cagacgattt tcccttgagg agtatgaatg acaatcccca aaggctctgg
     6121 aatagagtga gtcgttctaa agaaagttgc cttgagattt ttaaaggtca actcggtgtt
     6181 gtggttgatt tcgtaaagtt tggcgttgcg caagaggccg tgttcttcga gtttcccacg
     6241 gatcaaagcc aaggcaagcg gtccagcgta gatagggaca tttgcttgct tgagtaggaa
     6301 cggaatccca ccaatgtggt cctcgtgtcc gtgtgtgatt aaaacagcct tgacgcggtc
     6361 gatattgtcc acgatgtaag agtagtcagg aatgacatag tcgataccaa gcaagtcatc
     6421 ttctgggaat ttaatcccag catcgacgat gataatctcg ccttggtatt caattccgta
     6481 agtgtttttc ccgatttctc ctagaccacc gatggcaaaa acgccgactt cttcaggttt
     6541 aagagtgtag gccatattag aactccgtaa tttcgaaggc gccagtttct ttttcgtaat
     6601 cgagcaattt gtcagacaag agttcgatat attcgatatt gtactctggg cgattttctt
     6661 cgacaagttg gcgagcagtg atacggccct caagttctga gctggcatcg atgtctaggt
     6721 aaagcgcgcg tgttgtttca cggcgtgggc tacgttcttt tgtttcttga taaaaaactt
     6781 tgtaaatcat atagttcctt tctatttaca ggtcagctta ttccaaactt ttagcagata
     6841 tttgcttgat ttcattccat tttgtgtcta gattgacctt gattcgttac aattatttca
     6901 attataccac aaaatgaaaa attagtaaaa gacggaaacg agaaagttag gggacgattt
     6961 cttcggtaag cgtttgcgaa aataaagaaa atgtattatg ttgataacgg aagtgaaatt
     7021 tattgcttgt cataattcca tatagatttt aagtcaagga ggttgcccta tgtataactt
     7081 atttgctttt gctatcggag ttcgtttgct agcttttatc gtttttgttt tgcgtttatg
     7141 gaggaaatct tctatttgcc aaactggaac gatgacaaac caagttcttg aggaaaatta
     7201 cctttgtgac tctctactcg ctttttctcc tcctcgtgac ctatgtcgtt tggtttgtat
     7261 tttactttgg attaaatgct tagatgccct gcttatgctg gggttttttg tttggggatg
     7321 tagagatagt agatttacga cacgaaaatt ccaccccatc tatcaagatg aggtggtctt
     7381 tgcatttttc taaaatgata tgacaatgga attttcaaag cttattattt ttatgggagt
     7441 cattgttctg ctcaaaaata gagttgaagc ataaaaataa aacaatacaa acagataaat
     7501 cgaatggtaa agggatggta gtaatgttca aatcattgag aatgctgagc aaactgtaag
     7561 agatgaagac aataaaattt atccttctaa aaatgtgttt cttatctagc atgacttacc
     7621 aaacttttta cgaaggtctt ttccaatggt ataacctgcc ataaataaag cgataccaac
     7681 acctacacca aagccaccct tgatttcttg caattcctta ttagaaattt cacgacagtt
     7741 gttcaaatct ttcatcatat taatctcctc ctaaaaaata accagctgcc aaaccagaac
     7801 ctataagtgc tgttccacct gcaatagctt tccaagatac tgctactcca aagataacca
     7861 agggagcgag accgccatca atatctgata attcattttc agataaggat aaaaattgat
     7921 tgtcaagaat gtcaaaattt gtcattgaac tttcctcctt ttttcttgtt cacttttata
     7981 ttcggaaaag aaaaggaaaa gtgagcattt ttttaaatta tttttagtta agtgagggca
     8041 ctcttgtctg ggggcaaaga aaattcccat gtgccagctt ttgtagtata atagtaagca
     8101 gacaaaaaga taggaatgtg ttatgaaagt attagctttt gatacgtcca gcaaggctct
     8161 ttctctcgct attttagagg acaagcaggt tcttgccgag acgacgatta atattaagaa
     8221 aaatcacagt attactctta tgcctgccat agattttttg atggcaagtt tggattggac
     8281 acccaagaat ttggaccgaa tcgtggtagc tgaagggccg ggtagctaca caggcttgcg
     8341 aattgcggta gccactgcca agactttggc tcatactctg aacatcgagt tagttggtat
     8401 gtctagcctc ttggctctgg taccctacca acaagaaggc ttgttcgtct ctttgatgga
     8461 tgcgcgtcgc aacaatgttt atgtaggatt ttatgaaaat gctaaacccg tcatgccaga
     8521 agctcactta ccctttgagc gagtgattga gttaatcaag ggtgctagtc aggttacctt
     8581 tgtcggagaa gttggcccct ttgttgagca gattcaagaa tacttgccaa ggactaattt
     8641 caaagaaacc ttgccaaatg cagctaatct agctctatgg gcctgggaca aggaagcaga
     8701 ctccttgcat gattttgtgc cgaattacct caaacgagtc gaggctgagg aaaactggct
     8761 caagaaccat accgagtctg gtgagtccta cattaaacgc ctatgataga aatcaagcga
     8821 attcaacaac agcctgacct agctcaagcc atctacgctg ttatagcagc tgtttaccta
     8881 gtcagtcctt ggactctgga gcaaatccaa gcagatctgt cccaagacca gacttggtat
     8941 gcattggctt atgatggggc agaagtgatt ggatttctag ctgtgcagga gaatcttttt
     9001 gaagcagaag tcctgcaaat cgctgtcaaa ggagcctatc agggtcaggg aattgcgtca
     9061 gccttgtttg ctcaattgcc gacagataag gagattttcc tcgaagtcag aaagtcaaat
     9121 caacgagcgc aagcatttta caagaaagaa aaaatggcgg tcatcgctga gcgaaaggcc
     9181 tactaccatg acccagtcga ggacgccatt atcatgaaga gagaaataga tgaaggatag
     9241 atatatttta gcatttgaga catcctgtga tgagaccagt gtcgccgtct tgaaaaacga
     9301 cgatgagctc ttgtccaatg tcattgctag tcaaattgag agtcacaaac gttttggtgg
     9361 cgtagtgccc gaagtagcca gtcgtcacca tgtcgaggtc attacagcct gtatcgagga
     9421 ggcattggca gaagcaggga ttaccgaaga ggacgtgaca gctgttgcgg ttacctacgg
     9481 accaggcttg gtcggagcct tgctagttgg tttgtcagct gccaaggcct ttgcttgggc
     9541 tcacggactt ccactgattc ctgttaatca catggctggg cacctcatgg cagctcagag
     9601 tgtggagcct ttggagtttc ccttgctagc cctcttggtc agcggcggac acacagagtt
     9661 ggtttatgtt tcggaggcag gagattataa gattgttggg gaaacccgtg atgatgcggt
     9721 tggtgaggct tatgataagg tcggccgtgt catgggcttg acctatcctg caggtcgtga
     9781 gattgacgag ctggctcatc aggggcagga tatttatgat ttcccccgtg ccatgattaa
     9841 ggaagataat ctggagttct ccttctcagg tttgaaatct gcctttatca atctttatca
     9901 caatgccgag caaaagggag aaagcctgtc tacagaagat ttgtgtgctt ccttccaagc
     9961 agcagttatg gacattctca tggcaaaaac caagaaggct ttggagaaat atcctgttaa
    10021 aaccctggtt gtggcaggtg gtgtggcagc caataaaggt ctcagagaac gcctagcagc
    10081 cgaaatcaca gatgtcaagg ttatcatccc ccctctgcga ctctgcggag acaatgcagg
    10141 tatgattgcc tatgccagcg tcagcgagtg gaacaaagaa aacttcgcag gctgggacct
    10201 caatgccaaa ccaagtcttg cctttgatac catggaataa agagtggctc tttgtcaagt
    10261 gtagtgggta ggcgaaaagc tacaatctgg agagtacgaa attcgtactc tcttttttga
    10321 tgttcaaagt catcaaaatc cgttttttaa aattgttaaa gttccggaaa ccaaaggctt
    10381 tgcgcttgat aatcttaatc aaattattgg tcgcttcaag tttagcgttg gaataaggca
    10441 gcttaagtgc gttgataatc ttatctctat cccttaaaaa agtccaaaag accgtttgaa
    10501 aaagcggatg aaccgttggc agttcttgct caatcaatcc aaagaaatgg tcggcattct
    10561 tctcttgaaa atgaaagagc aggagttgat agagttcgta gtgaacctgt aatccctcag
    10621 agtaagacag cagcttatct cgtacttccc gatgggttaa gtgcattcga aacgtgggat
    10681 gatagaatcg tttctgacag agcttgaagc tatactggtg tagtaaatca gtccagtgga
    10741 ctgatttagc ccgagcctag aaacgaaaaa gcgagggttc caaaagcgct tgagcgcccg
    10801 atactccaag gattttcggt caaattggtt catgatttgg attcgtactc ggttcatagc
    10861 tcggctcaga tgttggacaa tgtggaagcg gtcaagaaca atcttcgcct ttggaaagag
    10921 ttgcttagcg agccgataat aagggctgta catgtccatg gtgatgacct cgaccagctc
    10981 ccgaacctct ctctgatagc gttggaaatg gtttcgaatc accgcatgag ttcgcccgtc
    11041 taaaattgcg aggatggatt tggactcaaa atcttgggca atgaagctca ttttgctctt
    11101 tttgaagcta tactcatccc aactcataac ttttggcaac ttggtccaat cggtttcaaa
    11161 cttaaattcc ctcagttttc ggatgacggt ggaagttgag accgccaatc tgtgggcaat
    11221 ctcagtcata gactgctttt caaggaggag ctgagcgatt ttttgtctca ccatgttgga
    11281 aatctggcaa tttttcttga caatggatgt ttgagaaacg accaccttaa ggcaattctt
    11341 gcactgaaag cggcgctttt tgagatgcag taccgtgggt aaaccctgac agtcgagaag
    11401 cggaatttta gaggctttct ggaagtcgta tttgatcatc ttcccttgac aatgaggaca
    11461 aggaggagcg ggggaatcca actttgcctg aacgactaga tgggtttggt atttcagaac
    11521 agacaagatt ttgatatttt tgtcttccaa tccgagcaaa tctgtggtat tcttaagttg
    11581 ttccatatga cccctttcta atgagttggt tagacgcttt tcattatagg tcatatgggg
    11641 ctttttttct acaagaaacg accctataat tcctggggtg ggattaccca ctacagaaat
    11701 tatagagcca aaacattcca aagtattgtc tgactctgga atgttttctg ttcacagttg
    11761 ttttgtaact gcctaataag taaccgcgct ataacgaggt atctaccgag attgtcaatt
    11821 ctccagtata ctgttataaa aaacaaaact ggaggatttt tttatgtccc cccatcgtcc
    11881 catcgactgt tccgtagctg cccaataacg gagtatagtc ggctgaaaca agaataggac
    11941 aaaagtacct caagaaaagc atcgtaattt gacaatatta ttctgagatg tttttgatgt
    12001 aagcccatat tttctcaatg ggattatact cgggtgaata ggtaggaagt ggtagcagtc
    12061 tatgccctgc tccttacaca tgttcattct gtgaaacctt gcattgtcca taatgataag
    12121 ggatggtgta tctaaagtag gtagtaagaa tttttggaag caagcttcga aaaagtcact
    12181 cgtcatcgta tctttatagg tcatcggagc catagtatat tgaaacaaaa aagggcatta
    12241 gtacttctat aacagtatcg caatctctgg tgtgcgttgt ctcgatctta attcaaataa
    12301 ttatatcttc ttccagagag actaactgcc tgctcaaggc tcgatcatat tcgagataaa
    12361 aataggtctc aacccctgtc tcataaatat aaataggagt caggtagctt aagtgattca
    12421 attctttaag gaaccgattt actttttctg ggtcttgttc gcagtaggta cggctctttt
    12481 ttagactata tcccatagcc tttagagcgt aatgaatagt tgttggagga cagttgaatt
    12541 cagcagctat ttcagtcaaa taagcatcgg gatgagtttc aatatagatc tttaatttat
    12601 ctctatcaac tttttcaatt aatagtggaa gttttcttaa agttagtgtg ttgaaacgtt
    12661 tttatacagt gctaaaattt gaagtgtagt gcagatgtat ttgtaatagt attatagcaa
    12721 ttctttggag aaggtcgaga caagagaaaa taggtatctt tgagatataa gcatgattta
    12781 ctataaaatt attgagttat tcataaaaat ttctctatca aatatcataa tgcgtcgttt
    12841 aaggagatgg ttacaatgca atatagttgt ggaaaaataa atattaatat ccctgatgga
    12901 tatggagaca ttaaggatat agtgttttcg gctcatatta tagttaggta taataatgga
    12961 cattgtggag gtatagatcc gcatataatt ggactttgta aaaagcagat cagaaggatg
    13021 tttctatatc ctattttgat aatcgtatct agagattcaa aggttattga tgattataaa
    13081 aatttagata ttgcctatgt tgattgtact caatgttcaa ataattttga aactgcctta
    13141 cacgttaaaa atattttaaa attattaaaa atctaactta tacactgtca tggctactca
    13201 actaattatt ttttatatat gttaaaaaaa cttgacaaga atggatttgg aaaggttaag
    13261 acagtgataa catgccatgg atgggttgaa tataacttaa aaaagaaatt cttgacttat
    13321 tttgattttt ggacatattc tatgggagat gcttttattt gtgtatctga aactatgaaa
    13381 aaaagattgg agagtataat aaaaaaataa gaagatagtt gcaataaata acggaattaa
    13441 tgtatcaaat agcgatttaa atgtagtagg tgttcaagac tttaaaaaag aattttgtat
    13501 tccaaataac aaaaaaatca tttgttatgt tggaaggttg gatccagaaa aaaggccgga
    13561 tagattcctt gaatttgcag aaaaattatt tttagtcaga gaagatgtga tttttattat
    13621 ggctggaaat ggtagtatgt gggctgcttt gaaagaaaaa atttgccatt tgaaatgtag
    13681 agataatttc aggttacttg gtgaaatcta tccagctact atagtttacc aaatatcgga
    13741 tttattgtat attccttctg atacagaagg aatacctatg tgtgttttag agtcaatgtc
    13801 acaaggaact ccggttttag ctagtaatat tggcgggtta agtgaaatta ttgaacatag
    13861 ggttgatgga tttttatttg agaaggaaga tgttgaggga gtgtgtgctt gtgctaattt
    13921 tttactcaat gattctgagt atttgaaata tataggtgag aatagtaaat caaaaataag
    13981 aaaacatttt tctgtgcaaa aaatgtttgt agaaaccatg agagtatatg atgaattatt
    14041 agagaagagt agtcatggat aggaatatag atcaagaatt agtaagtatt ataataccaa
    14101 cacataatag gtatgaatct ctgattagag ctgtgaaaag ttgtttacat caaagttata
    14161 aaaatatcga agttataatt attgatgata attatagtaa tgtaaattta agaaataaaa
    14221 ttatccatca atttggctat accaatcata gaattaagtt aattttaagt aatgaagatt
    14281 taggtgcaac taatgccaga aacataggta tcaaaaattc tagaggtaag tatatatcat
    14341 ttttagacga tgatgatgaa tatatgccag atcgaatttt aaagttgatg gcttgtttta
    14401 aaaagagtag aatgaagaat ttagctttag tttatagtta tggaataata atttatccaa
    14461 atggtacacg agaagaggag aagaccgatt ttgttggaaa tcccttgttt gttcaaatgg
    14521 ttcacaatat agcaggtacg tcattttggt tgtgtaaaaa agaggtgcta gaattaatta
    14581 atggttttga gaaaatagat tcacatcagg acggtgttgt tttattaaaa ctacttgctc
    14641 aaggatacca aattgatata gtgcgagaat tcttggtgaa ttactacgct cacagtaaag
    14701 aaaacggtat cactggagtg acacaaaaaa caattaatgc agatgaagaa tattataatt
    14761 actgtaggaa atattttaat ttattgagtt tcaacgagag aatattggtt acaaagaaat
    14821 attattcttt aaacataaag cggttactat taataggaga caaatgcaag gctttaaaag
    14881 taatcaagaa ggcaagagaa gaaaaaattt ttaacgaatt tccttttttg gaatatatgt
    14941 tattatatca ttttggtttt ttctattgta tatatgacaa ctatgttcaa ttaaaattta
    15001 gaaagtgaga aactattgtg tatactatta taaaatcaaa tataaaaaaa tttagtttat
    15061 taacgatatt tattgttgct ggtcaattat tgctaattta tgcagcaact attaatgctc
    15121 tggtgttgaa tgaattaatt gcgatgaatt tagagcggtt tttgaaattg tcaatctacc
    15181 aaatgattgt ctggtgtggg ataatattcc ttgactgggt agtgaaaaat tatcaggttg
    15241 aagtgatcca agagtttaat ctagagattc gaaatagagt tgccacagac atctctaact
    15301 ctacctatca agaatttcat agtaaatcat caggaacata tctttcgtgg ctaaataatg
    15361 atgttcagac tttaaatgat caggctttta aacaactttt tttagtaata aaaggaattt
    15421 ctggtactat atttgcagtt gtgactctta atcactatca ttggtcattg actgtagcca
    15481 ccttgttttc attaatgatt atgctacttg taccaaaaat ctttgcatcg aaaatgcgag
    15541 aagttagtct aaatttaact aaccaaaatg aagctttttt aaaatctagt gagactatat
    15601 tgaatggatt tgatgtgtta gcgtccttga atcttttata tgtattgcct aagaaaatta
    15661 aagaagcagg aattttatta aagatggtta tacaaagaaa gacaactgta gaaacgttag
    15721 caggcgctat tagcttcttt ctcaatattt tttttcagat atctctcgtt tttttaacag
    15781 gctatcttgc aataaaagga atagtgaaaa ttggtactat tgaagcaata ggagcactaa
    15841 caggtgttat ttttacagcg ctaggtgaat taggaggtca attatcctct attattggta
    15901 cgaagcctat ttttttaaaa ttgtattcaa ttaatccaat tgagtcaaat aaaatgaatg
    15961 atatcgaacc aaatgaggtg aatagagatt ttccgttata tgaagcaaaa aatatttgct
    16021 ataagtatgg agataaagaa atattaaaaa acttaaattt ttgttttcaa cgtaatgaaa
    16081 agtatttaat tttaggtgaa agtggaagcg ggaaatctac attattaaaa ttattgaatg
    16141 gctttttgag agattatagt ggagaattgc gattctgcgg ggatgatata aaaaaaacct
    16201 cctatttaaa tatggtttcg aatgttctat atgtagatca aaaagcttat ttgtttgaag
    16261 gtacgattag agataatatt ttattggaag aaaattatac tgatgaagaa atactacagt
    16321 ctttagagca agttggtttg agtgtaaaag attttcctaa taacatttta gattattatg
    16381 ttggtgatga tgggagatta ctatcaggag ggcagaaaca aaaaattact ttagctagag
    16441 ggctaattag aaataagaga atagtattaa ttgacgaggg aacttctgct atcgatagga
    16501 gaacttcgtt agcgattgaa cgtaagatat tagatagaga ggatttgact gtcattattg
    16561 ttacccatgc tccgcatccg gaacttaaac aatattttac taagatatat caatttccaa
    16621 aggattttat ttaagaatat aggggaggga aacatgagat tctattgtga agcttatgag
    16681 gtaattactg aagagaaaaa agtatcattt tttatgtaga tgaaaaaccc ttaaggtatc
    16741 tgttatttga ctatatattt ctactagttc tagctaaaaa aaaatatccc aatcttatga
    16801 actgcacccc aaaagttaga tttattctgt ctaacttttg gggtgcagtt cattttgcat
    16861 agttttggca ttcatcctag atatccatat aaaatgtctg agattgttga aatgtctaaa
    16921 aaaatatcag atctaaacga taaaaaagaa tttcacaaaa agaactgtga gttgaggttt
    16981 caagatagtg ttcttgataa cataaatagt gtcccgggta caactcattt atttagttgt
    17041 ttaaatattc aaacattagt aaaaattatt ttatatattt ttcgatacaa cagttgtatg
    17101 aaaatattta attttagaga taaagagctt atctttttta ataagattgt aaatgggctg
    17161 atacaaaata ttgaggagaa tttagaggat gatattgaaa ggatattgaa atatttatat
    17221 atatgtttat ttaacgaaat attcattatt aagaataagg tgaatttttt tgatgatgtg
    17281 gaatttaatc agacacttag tgagttttta gataaattgt agagggaatg gttatgagta
    17341 acaatactaa gtatatcttt ttatctccac atttagatga cgcaattttt tcctgtagtg
    17401 attatatttc aaaattaact tcagaaggag aaattgtact tgttattact atattttctg
    17461 gttacccttt gagccaacag ctacagccct ctgctaagca atttcataag ttgtgtaacc
    17521 ttgggaaata tccgattgaa gaaaggaaga aagaagacag gttagcttgt gaacgtctac
    17581 aatgtgattt tagacactta tcgtactatg aatgtctcta taggaaagat agaaatggca
    17641 attttctata ccgtcatatc tatagtgaat taaaaaatga ggacacatta aagaatgata
    17701 tcataaaaga gctgttaatg catttagacg ataaatgtgt cgtatattgt ccgctttcac
    17761 ttggtgacca tgttgatcat gtttttgtga atagtattgg aagggcgctt gaatttatgc
    17821 gttataaagt aatatattat gaggacttcc catatgtaag tgatagtagt atggttagtt
    17881 atatgggaaa aactaaagaa ttaaaaatgt atcaagagga acttgatgaa aaacattata
    17941 ttgatagaat atcatcaata ttgtgctata aatctcagat tttgataatc tggaaatcag
    18001 ttgaaaaact tttaaacaat attaaagagt tgtatttaag gaatggggca gcttattcta
    18061 ttagattttg gattaagaaa taaggaagta gttttatgaa tatagcagta attggtttgg
    18121 ggcatgttgg gctggcctac gcgttactat ttgcatctaa atataaagtt gttgcatatg
    18181 atatagattc tgtaaaaata aataatttaa aaaagggcat tcttccatct aaaaatgaag
    18241 agcttatgaa gtttttttgc gagaataact taaatattac tttttttgat acattttctg
    18301 aaattaaaaa taatattgat tattatatta ttgcgcttcc gacagattat gatgagaaaa
    18361 ttggtagttt taatacatat gaaatcgaac aaacggtatc gaagattctg agggtaaaac
    18421 ctaatggaaa gattatttta aagtcaacag ttccgttcgg cttttcaaac aaattaaaaa
    18481 ggctgtttga tacaaaaaat atcatttttg tccctgaatt tttgagagaa ggttgttcta
    18541 tatatgataa tttatatcca agtcgcatag ttgttggaga tgagacagtt gaaggaagaa
    18601 aaattgcaga gttgttcctt tcgattagta ctcatagtac tgccaatatt aaaaatgtta
    18661 tgttagtttc tcctactgaa gcagaagcaa ttaagctttt ttctaacaca ttcttagctc
    18721 tccgtgttgc tttttttaat gaactagatt cttttgctga gaggagaagt ttaaatgctg
    18781 aagttgtaat aaaaggtgtt tgtttagatc caagaattgg aaatttttat aataatcttt
    18841 cttttggatt tggaggatat tgtcttccca aagatactaa acaattaaaa aaagaattta
    18901 tagaaataaa tgccccagtg atagaagcga ttgatatttc aaacacaaat agaaaacagt
    18961 tcatagttaa acaaatattg gaacgaaagc caaagatagt aggaatatat aaattgggga
    19021 tgaaatataa ttcagataat tacaaagagt cagctatttt aagtataatt aatgaactat
    19081 tgattgtcgg tataaaaatt ttagtatatg aaccaaattt aaacgttagt atagataacg
    19141 taatttttga aaagaatttt gaactattta caaaacaaag tgatctaatt gttgcaaata
    19201 gatgggatag gggccttgaa gcttataaag ataaagttta cacaaggggg atctggataa
    19261 gagattaact attgatatta aaaaggcaat aatttataaa atttgtacaa aaaaatgtta
    19321 aattttcaca ttttcatagt atactgttta atagaaagta ggttctttgt aaccgctcca
    19381 ttataaaatc ctttcactct tccggtatac tattaggaaa aacataactg gaggatattt
    19441 tgagctcaca cctcatcgtt ccagtggctg ttccccaagc tcgtgtactg cccaaaaaag
    19501 ttagacattc tatttagaac gaggattgag ttctgtattg tacaaggctc ggtcctttta
    19561 gagtcagctt aaggctggct tttttatttt ttctaactat cagaatattt tgacaaatga
    19621 acacaaataa tgatataata tgcaaaagct aggaggtggt aggatgattg aaaaaatgga
    19681 attgggggaa ttttacaagg aattacgttt ggcgagaaag ctcaagcagt cagatgtggc
    19741 ttgtgacggg ctaacagctt ctcagttgtc caagtttgag ctagggcagt ccatgttgtc
    19801 tgctgataag ctcatattag ccatccaagg gatcaatgtg acctttgatg agtttgggca
    19861 caagctcaac aactatcaag aatctccaca tatgcagatt ggtagaaagg ttgtggatcg
    19921 ctttgctcat caagatatag ctggcttaga gcaactgttg gaggaagtcg agcaagaaca
    19981 gatggcagag acttatcgtc gtttgaatgc tattgtaatc aaagatgcca tccactcact
    20041 agataaaagc tacccactag cagaggagga tagcgagttt ttgaccacct atctctatgc
    20101 tatcgagtct tggacctggt ttgaactcta tctcttttgc aatactctgc ccttcttgag
    20161 caatcaagat ctgatctttt tatcaacctc cttactcgaa aaatccaaag aatttaaaga
    20221 gttagtacac aatcgattgt atatgaagca aggactctta aatatcatct cagagctcat
    20281 ggagcgcaaa cttttttctt atatcccaat ctttgaagcc gagctggaga gtatgctccg
    20341 tccatacgat gtttttgaga aagtgttgtg gcagttttta aagaagatga gcattttcct
    20401 tcaaactaag ggaagcaatc aaaaagagat tgaacacttt atccaatctc tgcaagtatt
    20461 agaaaatcca caattaatag ccctttttga attgcgtttg cagcaataca aaaagcttat
    20521 cgattagtta gaaatggcaa aataataata atctcagcaa cgattttcaa taatgttaaa
    20581 atttgtttct tcatatttct ccactcctca ttagtagtaa ctttattata ccagagaagt
    20641 aatcaaattc accaaaatcg caaatctgaa atttctataa gaaaaaatat caaatatgcg
    20701 attttctaaa ataagccaat tttcgtgtta tactgtactt gtaaagcact tgaagcaaat
    20761 cctaggtcac agaagtggtt tacaaatgaa gataattgaa ggagtgtaaa agatgttaaa
    20821 tttacaattt gcagaaacaa tggaattgac agaagctgag ttggagatag tttatggagg
    20881 ggaatttggg aataatgctg ttatcccagc cggtgcttgg ggagggttcg ggacaccttg
    20941 gtcaatcact aatttctgga agaaaaattt taacgataga cctgactttg attctgaccg
    21001 ccgtcgttat taatatccaa agcccttgcc ttttcttggg taggggctgt ctttatttca
    21061 tagtatagga ggaaatagaa tgaaaaagat aatctcacac cgctacttta ttatagtttt
    21121 tctactagtt attgctgacc agaagttcag tgttctagtt ttacgcagcg accttgttac
    21181 tgggctatct gactttgcct attatctgtc ggatatgatg ttgaattttc ttgtggtttt
    21241 atttgctctt attgctatga tttggtcggg gaaatggcag aaaatcaata gtagaaagtt
    21301 taaaggatcc tatcttttct attccttcct agctctgctt gcttttgttg tttggaattt
    21361 cgttaccttt tttcttttcc cacctactcg aaatgaaatt tcttatcaac atgctgctcc
    21421 gacttttaca ggggctacag catttttgat gtattttttc tatcctgtga ttgcaggtcc
    21481 catttttgaa gagataatcc atcggggatt ggtgatgaca gctctggaaa aaggaaagaa
    21541 atgggggcta gatgtacttg gctctgctat tttatttggg gtctcgcaca ttagtaatca
    21601 cggttgggtc ttgacagact ttgtcttcta tatgggtgga ggtcttatat ttgcagtctt
    21661 atttagaatg acaaagtcaa tttattggcc tattggactg catatagtct acaatggtat
    21721 tggtcagctt ttgatgttac tgtaattttg gttgttagta gtatcgcggt ctattcttgg
    21781 ggaaagattc ccatttgaac ttaagaagga gttgtaatga aagtatttct tcaaaataga
    21841 gattttaggc aattaactat caaccagtgg atttcaacgc ttggggatac gattttttat
    21901 ctggccttcc tgaattatgt ggcagatgcg tcttttgccc ctttggcgat tttacttatc
    21961 acgatttcag aaacccttcc ccaagttcta caaatctttc tgggagtttt ggcggatttt
    22021 caacatcatc gtgtcttgaa atacacagtc attagtttta caaaattttt gctttactct
    22081 atagtgtccc tatcgctttc agggcagtct ttttccttgt tgctagtaac ctttatttgt
    22141 atgattaacc tcttgtctga cacattgagt tatttttcag gcgccatgct cactccgatt
    22201 ttcattagaa ttattgggca agatcatctg gcagaagcta ttggatttaa acagtcaact
    22261 gttagtttag tgaaaacaat cagtaatatc ctaggaggag tcttactagg tattctatcc
    22321 atccagttta tttccttact gaacgctctt acctttttaa tcgcattttt aggtatcctc
    22381 ttcataaaaa ctgacctctt gaaagtagaa aaaacgatta gctatcaaga aggactctct
    22441 gtaaaatcct tttgccagca tttgctccaa tcatcgaaat tgatatggaa tatgaataag
    22501 gtgctcttgg ttttgtttat tatctctact agtcaagcag tgataaatgt tacagttcct
    22561 gtctctactc tatttttgag gaatcaaccc tttttgaatt tacaaacagg tcaatctctt
    22621 gccttgctat ccacttttga actgtcagcc ctgattgtcg gaagccttgt aagtggctat
    22681 ctgcaacata ccatttccat aaaaacagct ctctatgcct cacttgtcat ccagttgctt
    22741 cttctagtag gatttgccac agttcgtttt gactggattc tcatctttag taccttggat
    22801 gcctttttcg caggtgttct ctctcctaga ttgcaagaac tcgtctttaa acaaatacct
    22861 gaggagtcaa tgggagcagt tcaatcttct atcagtgcca ttacggttgt tttacctagc
    22921 ttatttacaa tatctttggt aaccattgct actagctttg gaactctggc agttagcttt
    22981 gttttattgc tatttcttct agttgccttt gttatgcttc tgaatattcg tgaaagtatt
    23041 tagtggagaa tttctataat atatgtttga gactggattg ccagtctttt tatgatggtc
    23101 aaaatcaaca gactttttct cttttctgaa tgtg
//
LOCUS       DBEJZV010000028        22999 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.28, whole genome shotgun sequence.
ACCESSION   DBEJZV010000028 DBEJZV010000000
VERSION     DBEJZV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.28"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..245
                     /locus_tag="ACL3S0_001531"
     CDS             <1..245
                     /locus_tag="ACL3S0_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGR1312419.1"
                     /translation="GLMKIYPQVQTPRKSSKLKPLTVEDKACNHALSKDRSKVENIFA
                     KVKTFKMISTTYRNHRKRFGLRINLIAGIINHELGF"
     gene            395..649
                     /gene="blpM"
                     /locus_tag="ACL3S0_001532"
     CDS             395..649
                     /gene="blpM"
                     /locus_tag="ACL3S0_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HGR1312420.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            665..868
                     /gene="blpN"
                     /locus_tag="ACL3S0_001533"
     CDS             665..868
                     /gene="blpN"
                     /locus_tag="ACL3S0_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HGR1312421.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1112..1261
                     /gene="blpO"
                     /locus_tag="ACL3S0_001534"
     CDS             1112..1261
                     /gene="blpO"
                     /locus_tag="ACL3S0_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGR1312422.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1365..1484
                     /locus_tag="ACL3S0_001535"
     CDS             1365..1484
                     /locus_tag="ACL3S0_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR1312423.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2270..2689
                     /locus_tag="ACL3S0_001536"
     CDS             2270..2689
                     /locus_tag="ACL3S0_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGR1312424.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEVGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKTNCLLNLTAVESDKVRS"
     gene            2704..3393
                     /locus_tag="ACL3S0_001537"
     CDS             2704..3393
                     /locus_tag="ACL3S0_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR1312425.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFSGVMIWILVKTGHGYLFRIPRKKWLWYSILTVLVLVLQISFNVQIAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYVTLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     FLPSILFALPHFSSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3435..3668
                     /gene="blpZ"
                     /locus_tag="ACL3S0_001538"
     CDS             3435..3668
                     /gene="blpZ"
                     /locus_tag="ACL3S0_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGR1312426.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLSSDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            3819..4430
                     /locus_tag="ACL3S0_001539"
     CDS             3819..4430
                     /locus_tag="ACL3S0_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR1312427.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIVIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            4591..5385
                     /gene="ccrZ"
                     /locus_tag="ACL3S0_001540"
     CDS             4591..5385
                     /gene="ccrZ"
                     /locus_tag="ACL3S0_001540"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGR1312428.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5382..6017
                     /gene="trmB"
                     /locus_tag="ACL3S0_001541"
     CDS             5382..6017
                     /gene="trmB"
                     /locus_tag="ACL3S0_001541"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGR1312429.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6143..6622
                     /gene="rimP"
                     /locus_tag="ACL3S0_001542"
     CDS             6143..6622
                     /gene="rimP"
                     /locus_tag="ACL3S0_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGR1312430.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6666..7802
                     /gene="nusA"
                     /locus_tag="ACL3S0_001543"
     CDS             6666..7802
                     /gene="nusA"
                     /locus_tag="ACL3S0_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGR1312431.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7824..8117
                     /locus_tag="ACL3S0_001544"
     CDS             7824..8117
                     /locus_tag="ACL3S0_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGR1312432.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8110..8409
                     /locus_tag="ACL3S0_001545"
     CDS             8110..8409
                     /locus_tag="ACL3S0_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGR1312433.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8426..11218
                     /gene="infB"
                     /locus_tag="ACL3S0_001546"
     CDS             8426..11218
                     /gene="infB"
                     /locus_tag="ACL3S0_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGR1312434.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11469..11819
                     /gene="rbfA"
                     /locus_tag="ACL3S0_001547"
     CDS             11469..11819
                     /gene="rbfA"
                     /locus_tag="ACL3S0_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGR1312435.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            12098..12877
                     /locus_tag="ACL3S0_001548"
     CDS             12098..12877
                     /locus_tag="ACL3S0_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312436.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYLILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            12879..13061
                     /locus_tag="ACL3S0_001549"
     CDS             12879..13061
                     /locus_tag="ACL3S0_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312437.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            13476..13709
                     /locus_tag="ACL3S0_001550"
     CDS             13476..13709
                     /locus_tag="ACL3S0_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGR1312438.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            13709..15043
                     /locus_tag="ACL3S0_001551"
     CDS             13709..15043
                     /locus_tag="ACL3S0_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGR1312439.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEVFEAFAIEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            15053..15307
                     /locus_tag="ACL3S0_001552"
     CDS             15053..15307
                     /locus_tag="ACL3S0_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGR1312440.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            15403..15798
                     /locus_tag="ACL3S0_001553"
     CDS             15403..15798
                     /locus_tag="ACL3S0_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR1312441.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            16082..16645
                     /locus_tag="ACL3S0_001554"
                     /pseudo
     CDS             16082..16645
                     /locus_tag="ACL3S0_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            16648..17208
                     /locus_tag="ACL3S0_001555"
     CDS             16648..17208
                     /locus_tag="ACL3S0_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR1312442.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEVI"
     gene            17208..17786
                     /locus_tag="ACL3S0_001556"
     CDS             17208..17786
                     /locus_tag="ACL3S0_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR1312443.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            17779..20430
                     /locus_tag="ACL3S0_001557"
     CDS             17779..20430
                     /locus_tag="ACL3S0_001557"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGR1312444.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            20500..21255
                     /locus_tag="ACL3S0_001558"
     CDS             20500..21255
                     /locus_tag="ACL3S0_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HGR1312445.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            21532..22335
                     /locus_tag="ACL3S0_001559"
     CDS             21532..22335
                     /locus_tag="ACL3S0_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGR1312446.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYENATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(22451..22999)
                     /locus_tag="ACL3S0_001560"
                     /pseudo
     CDS             complement(22451..22999)
                     /locus_tag="ACL3S0_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         6993 a         4149 c         5152 g         6705 t
ORIGIN      
        1 aaggactcat gaagatatat cctcaagtac aaactccacg taaatccagc aaactcaagc
       61 cactaacagt tgaagataaa gcctgtaacc atgcgctatc taaggataga agcaaggttg
      121 agaacatctt tgccaaagta aaaacgttta aaatgatttc aacaacctat cgaaatcatc
      181 gtaaacgctt cggattacga ataaatttga ttgctggtat tatcaatcat gaactaggat
      241 tctagttttg caggaagtct aatgtaattt ttgcaattca agacgtttcg atgactattc
      301 aagatctgga tgaaaaattt taaaaaacga tgatatacta aacttgtcaa agttacaaca
      361 agacaaaaat taaaaataaa aaagagtatt tgtcatggat acaaaaatta tggaacaatt
      421 tcatgaaatg gatataacta tgttatctag tattgaagga ggcaagaata attggcaaac
      481 taatgtctta gaaggtggtg gtgctgcttt tggtggctgg gggctaggaa cagctatttg
      541 tgctgcgagt ggtgttggag caccatttat gggagcatgt ggatacatag gagctaaatt
      601 tggtgtggat ctttgggcag gagtaacagg ggcaacgggt ggattttaat aaaaggagac
      661 ttgtatgaat acttattgta atataaatga aacaatgctg agtgaggttt atggaggtaa
      721 ttccggagga gcagctgtag ttgctgcttt aggttgtgca gcgggtggag tgaaatatgg
      781 gagacttcta ggaccatggg gcgctgcaat aggaggaatt ggaggagcag tggtttgtgg
      841 atatttagcc tataccgcta catcataaaa atgaaagcta aattttatga aggctatatt
      901 ctttattatt ctcttcgctt ttcaaaccta tcttatttat ctatccataa gtatctctga
      961 taaaaaacaa aagactattg aattaacatc attgaattgt tttgtcatat tatttctaat
     1021 ctacgataaa ttaatttttc tctttattgc ctatgttttt ttgataattt ttatattaaa
     1081 cttgttccgt aactgaaaag tgacatacta tatgaataca aaaatgatgt cacaattttc
     1141 tgttatggat aatgaaatgc ttgcttgcgt tgaaggtgga gatattgatt ggggaagaaa
     1201 aattagttgt gcagcagggg ttgcatatgg cgcaattgat gggtgtgcaa caacggtttg
     1261 acatttctat tgggaccatt tgctatagga ataggtgtaa ctggtgctgc aggtggagct
     1321 atacttggag gtgtagccta tgtagcaaca tgttggtggt aattatggat tttaaaagtt
     1381 ttattattgg tttagtagtt ggtatatttg gtccttatat ggatgactta attagaaaaa
     1441 tattttcaaa atcttccaaa aaggatacgg atagtactct ctaaaaaata aatttctccc
     1501 ctgtatttgc tagcttaatt tacaggggag tttctttaat attgtttcgc ctgtcaaaat
     1561 gatatgtgat agcaggatga aaagtctaca aacaagttgg tatcaataca atataaagag
     1621 gaaagtatgt ttttaatgct tactttttaa attttttaac aattcaagat gtttcgatga
     1681 caattcaaga tttggatgaa aaattttaaa aaacaatgat atactaaact tgtcaaagtt
     1741 gcaacgggtg ctgctacatt atgttaaaaa tcgctcttga ttgataagct ggatttgtta
     1801 ggaaaggagt aaataattat ggataagaaa aagatagttt cgactataat atgtatagta
     1861 tttcttgtag tgtcagtaga taattttttt agagacttaa ccccgttact gttcatttta
     1921 aatattattg gcctgtcttg cttttcagtg ctaacataca ttaacataaa agagatactc
     1981 ttaaatataa gtaaatgatg atttggttag tcctagaacc aatcaactta tgtttatcgg
     2041 cttggcagat tttatgtttg tcatttgttt gtatagaggt atttcagaaa cagaattcta
     2101 tcaacaacta atcgcttata taggtgtatt ctctgcttgt ttatcacgct tctgctcatg
     2161 tggggcttga agtattataa aaagtagctt tctatccttt tctgacagga tatttgagta
     2221 gaaggctcta ttaaattgtt agtgaaataa atgaatggag gtatttaata tgaaatacag
     2281 attatttttt gttattttct tgagtagtgt gttggatatt cttttaggga catttttaca
     2341 aatctctatc gtatctattg ggtggcttgt tctttacagt ggtttgtttg aagtaggagt
     2401 tttccttctt gctaataaag gggtggcggt aaaaatcaag gaagtagata ttcgaaatcg
     2461 ctttaaattt atttttggaa aaaccttatg gtttcaaatt cttttgctca tctttttgat
     2521 aatcaaactt tatcttggtt tggatgcgag gttgatttta ttctatggac atattttcat
     2581 tgtctttaat gccttaatgt atctattatc tagtagtcag gttagcctta aaaaaacaaa
     2641 ctgtcttctt aatcttacag cagtagagtc tgacaaggtg agatcatagt agggaggatt
     2701 tctatgaaaa agtatcaact tctattcaaa ataagtgcag tcttctctta cttatttttc
     2761 gtatttggtc tttctcagct gacgcttatc gtccaaaatt attggcaatt ttcttcccag
     2821 attggtaatt tcgtctggat tcaaaatatc ttgagtttac tatttagcgg agtcatgatt
     2881 tggattctgg ttaagacagg ccatggttat ctctttcgca ttccaagaaa aaaatggctt
     2941 tggtattcga ttttgacagt attagtgcta gtgctccaga tctcttttaa cgttcagata
     3001 gctaaacatg ttcagtcaac tgctgaaggt tgggccgtat tgatcggtta tagtgggacc
     3061 aactttgctg agctaggtat ctatgtaacc ctgtttttct tgactccact aatggaagag
     3121 ttgatttata ggggattact gcaacacgcc ttctttaagc attcgcgatt tggccttgat
     3181 ttgtttcttc cgtccatttt atttgctctt cctcattttt caagcctacc tagtttgtta
     3241 gatattttcg tctttgcaac atttggaatc atctttgccg gtttgacccg ctataccaag
     3301 agtatttatc catcctatgc ggtgcatgtg atcaataata ttgtagcgac cttcccgttt
     3361 ttgctcactt ttctacatag ggtcttgggg taaaaaaaca aaaggcttgc ttttcagcca
     3421 tagaggaggt catcatgtat aaacacttat ttttcctaga ttccaaaact ttagatcggt
     3481 tgacacccta tattctagtc ttgtcttctg acaccattgc ttttaatgtt tttgtgctaa
     3541 cctttgtatc tgcggtggtt tttaatttcc taaattccat gctagcttta atggctatat
     3601 tcataggggc tggctatgtg gtcggatttt ggttactaat actcaatgaa aatcaaagag
     3661 caaactagga aactagccgc aggctgtact tgagtacggc aaggcgacgt tgacgtggtt
     3721 tgaatttgat tttcgaagag tataaaatgg tttgttttgg aaaggctaga actaaagaat
     3781 gacgtgtagg aagtctgttt gttgaggagg ataattttat ggagtttttt gataaatttc
     3841 atgccttgtg ttttggattt ttagtactaa taattgtcat tacagttcct tatacgatta
     3901 accatgggga tttttttcaa aatgaatctg cattgattat tgtaagtctt cttgtaacct
     3961 cgctgagtgt tgcttatgct agaaagtttg aaatgatttc ttttgggatg ttaagcaaga
     4021 aacaactttt gcttttcatt gtaatctttc ttctaagtgt acttgagacg ctggtttata
     4081 ttcatttctt cgctgtttct tctggctcag gggtccaaca cttggcggaa gtcagcagag
     4141 gaatttccct gtctttgatt ttgactacct cagtttttgg ccccatccag gaggaactca
     4201 ttttcagagg acttcttcaa ggtgcggttt ttgacaattc ttggttaggg cttgtgctaa
     4261 cttcctctct cttttctttc atgcatggac cttctaatgt cccttcgttt attttttatc
     4321 tacttggggg cttgttgctg ggccttgctt ataaaaagag ccaaaaccta tgggtttcta
     4381 ctctagtcca catgttttac aacagttggc cactcctata ttatttataa aaattatgaa
     4441 aaggtaagca gaagacggtg cttacctttt tcaagctata atgataccca agccaatcca
     4501 gaggcttttc tttgagaatc gggttagagt ggttgacgaa taggccaaaa actagtagaa
     4561 tagtaaggaa actttatacg gaggaaagaa atggatttgg gtgataatga gctaacactg
     4621 actcccatac ctgggaaaag tggcaaggct tatatgggta gctatcctga tgggaagcgc
     4681 atctttgtaa aaatgaacac ctctccaatc ctacctggtc tagctagaga acaaattgct
     4741 ccacaattat tatggagtcg tcgtttggca gatgggcgtg atatgtgtgc tcaagaatgg
     4801 ttgacaggca agatattgac cccctatgat atgaatcgta agcaaatcgt caatatttta
     4861 acccgtcttc atcgctcacg tccgttgatg acacaattga gtcgtttggg ctatgccatg
     4921 gaaacacctg tagatttact acagtcttgg caagaaacgg ctccagatgc tttgcgtaaa
     4981 aatcatttta tcagtgaagt gatggctgat ttgcgtcaga ctattccagg atttagagag
     5041 gaccatgcga ccattgtcca tggagatgta cgacatagta attggattga gacagatagt
     5101 ggcttgattt atttagtaga ttgggattcg gttcgcttga ccgatcgcat gtttgatgtg
     5161 gcccatatgc tctgccatta tatttcagaa catcagtgga aggaatggtt gacctactac
     5221 ggttacaagt acaatcaaac ggtattaagt aaattgtatt ggtatggtca attgtcttat
     5281 ttgagtcaga tttccaagta ttatatgaac caagatttag aaaatgtcaa tcgggagatt
     5341 catggtttgc gtcatttccg agacaagtat ggaaagagaa gatgagagtt agaaatcgta
     5401 aaggggcaac agaattacta gaggcaaatc cccagtatgt ggtcctcaat cccttggaag
     5461 ccaaggcaaa atggcgggac ttgtttggca atgataatcc cattcatgtg gaagttggaa
     5521 gtggaaaggg tgcctttgtt tcaggtatgg ccaagcaaaa ccctgacatc aactatatcg
     5581 ggattgatat tcaaaagtct gttttgagct acgctttgga caaggtgctt gaagttggag
     5641 tgcctaacat caagctcttg tgggtagatg gttctgactt gactgactac tttgaagacg
     5701 gtgagattga tcgcttgtat ctgaactttt cagatccatg gccgaaaaaa cgccatgaaa
     5761 agcgtcgttt gacctacaag acctttttgg acaccttcaa acgtatcttg cctgaaaatg
     5821 gagaaattca tttcaagacg gataaccgtg gcttgtttga gtacagttta gtgagctttt
     5881 ctcaatatgg catgaaactc aatggtgtct ggctagattt gcatgccagt gattttgaag
     5941 gcaatgtcat gacagaatac gagcaaaaat tctcaaacaa ggggcaagtt atctaccgag
     6001 ttgaggcaga attttaagag atagcctaaa attaggctgt acaagtgctt ttgctttaca
     6061 taagttggca aacgtgctat actgatagta agaatatgaa aagtgaggcg gggaaatatc
     6121 ttcgcctctt gcttatgagg aggtggacgc aatcgcaaca atcgtagaat tagtcagaga
     6181 agttgtagaa cctgtcatag aagctccttt tgaactcgtg gatatcgagt atggaaagat
     6241 tggcagtgac atgattctca gtatttttgt agataaaccc gaaggaatta ccttgaacga
     6301 cacggcagac ttaacagaaa tgatcagtcc tgtcctagac accatcaagc cagatccctt
     6361 cccagaacaa tatttcctag aaattaccag tccaggcttg gaacgtcctt tgaaaaccaa
     6421 ggatgccgtc gctggagccg ttggaaaata catccatgtc gggctctacc aagccatcga
     6481 taagcaaaag gtctttgaag gaaccttgtt ggccttcgaa gaggacgagt tgactatgga
     6541 atatatggac aagacgcgta agaaaaccgt ccaaattcca tacagtttag tatcaaaagc
     6601 acgtttagca gttaaattat agaaaaagaa aggatagctt ttgaggattc aaaagtgaag
     6661 aaaacatgag taaagaaatg ctagaggcct tccgcatttt ggaagaagac aagggaatca
     6721 aaaaagaaga tatcatcgac gcagtagtag agtcgcttcg ttccgcttat cgcagacgct
     6781 atggtcagtc agacagcgta gctattgact tcaacgaaaa aacaggtgac tttacagttt
     6841 atactgtccg tgaagttgtt gatgaagtat ttgatagccg tttggaaatc agcttgaaag
     6901 atgctcttgc cattaattca gcttatgaac ttggagacaa aatcaagttt gaagaagcac
     6961 cagctgagtt tggtcgtgta gcagcccaat ctgccaaaca aaccatcatg gaaaaaatgc
     7021 gcaagcaaac acgtgccatc acttacaata cttacaaaga acatgagcaa gaaatcatgt
     7081 ctggtacagt agaacgcttt gacaaccgct ttatctatgt caaccttggt agcatcgaag
     7141 cccaattgtc aaaacaagac caaattcctg gagaagtttt tgcttctcat gatcgtatcg
     7201 aagtttatgt ttacaaggtt gaagacaacc ctcgtggtgt gaacgtcttt gttagccgta
     7261 gccatccaga aatgatcaaa cgtttgatgg agcaagaaat tccagaagtt tatgatggaa
     7321 ctgttgaaat catgagcgtg gctcgtgaag caggtgaccg tacgaaggtt gctgttcgta
     7381 gccacaatcc aaacgtagat gctatcggta caatcgttgg acgtggtggt gctaatatca
     7441 agaagattac tagcaaattc cacccagctc gttacgatgc taaaaatgac cgcatggtac
     7501 caatcgaaga aaatatcgat gttatcgagt gggtagcaga tccagctgaa tttatctaca
     7561 atgccatcgc tcctgctgag gttgaccaag ttatctttga tgaaaacgac agcaaacgtg
     7621 ccttggtggt tgttccagat aacaagcttt ctcttgccat tggtcgtcgt ggacaaaacg
     7681 tgcgcttggc ggctcacttg actggttatc gtatcgatat caagtctgct agcgaatttg
     7741 aagccatgga agacgctgct tcagtagagt tggaagtaga aaacgatact gtagaagaat
     7801 aaaagctgct agaggaggga aagatgaaaa caagaaaaat ccctttgcgc aagtctgttg
     7861 tgtctaacga agtgattgat aagcgtgatt tgctccgcat tgtcaagaac aaggaaggac
     7921 aagtctttat tgatcctacg ggcaaggcca atggccgcgg cgcttatatc aaactagaca
     7981 atgcagaagc cctagaggcg aaaaagaaga aggtctttaa ccgcagcttt agcatggaag
     8041 tggaagaaag cttttatgac gagttgatcg cttatgtgga tcacaaagtg aaaagaagag
     8101 agttgggact tgaataagca aaagataagt aatctcttgg ggcttgctca gcgagcaggg
     8161 cgcatcatat cgggtgaaga attggtggtc aaggccattc aagacggcaa ggccaagttg
     8221 gtctttctag ctcatgatgc tggacccaat ctgaccaaga agattcaaga taaaagtcat
     8281 tattatcaag tagaaattgt aaccgtgttt tcaacactgg aattaagcat agcagtcggg
     8341 aaatcgagaa aggttttggc tgtaacagat gctggattta caaagaaaat gaggtctctt
     8401 atggaataga agaggaggac atgatttgtc taagaaaaga ttgtacgaaa tcgcaaaaga
     8461 acttggaaaa gaaagtaaag aagttgtagc gcgtgcaaaa gagttgggct tggatgtgaa
     8521 aagccactca tcaagtgtgg aagaagctgt cgctgcaaaa attgctgcca gctttaagcc
     8581 tgcagctgct ccgaaagtag aagcaaaacc tgcagcacca aaagtaagtg cagaaaagaa
     8641 agccgaaaaa tctgagccag ctaaaccagc tgtagctaag gaagaggcaa aaccggctga
     8701 gccagttgct ccgaaaacag aaaaagtagc agcgaaaccg caaagtcgta atttcaaggc
     8761 tgagcgtgaa gcccgtgcta aagagcaggc agaacgacgc aagcaaaata agggcaataa
     8821 ccgtgaccaa caacaaaacg gaaaccgtca gaaaaacgac ggccgtaatg gtggaaaaca
     8881 aggtcaaagc aaccgcgaca atcgtcgctt taatgaccaa gctaagaagc agcaaggtca
     8941 gcaaaaacgt agaaatgagc gccgtcagca agaggataaa cgttcaaatc aagcggctcc
     9001 acgtattgac tttaaagccc gtgcagcagc cctaaaagca gagcaaaatg cagagtacgc
     9061 tcgttcaagt gaggaacgct tcaagcagta tcaggctgct aaagaagcct tggctcaagc
     9121 taacaaacgc aaggaaccag aggaaatctt tgaagaagcg gctaagttag ctgaacaagc
     9181 acagcaagtt caagcagtgg ttgaagtcgt ccctgagaaa aaagaacctg cagtggatac
     9241 acgtcgtaaa aaacaagctc gaccagacaa aaatcgtgac gattatgatc atgaagaaga
     9301 tggtcctaga aaacaacaaa agaatcgaag tagtcaaaat caagtgagaa atcaaaagaa
     9361 tagtaactgg aataacaaca aaaagaacaa aaaaggcaat aacaagaaca accgtaatca
     9421 gactccaaaa cctgttacgg agcgtaaatt ccatgaattg ccaacagaat ttgaatatac
     9481 agatggtatg accgttgcgg aaatcgcaaa acgtatcaaa cgtgaaccag ctgaaattgt
     9541 taagaaactt ttcatgatgg gtgtcatggc cacacaaaac caatccttgg atggggaaac
     9601 aattgaactc ctcatggtgg attacggtat cgaagcaaaa caaaaggttg aagtggataa
     9661 tgctgacatc gaacgtttct ttgtcgaaga tggttatctc aatgaagatg aattggttga
     9721 gcgtccacca gttgttacta tcatgggaca cgttgaccac ggtaaaacaa cccttttgga
     9781 tactcttcgt aactcacgtg ttgcgacagg tgaagcaggt ggtattactc agcatatcgg
     9841 tgcctaccaa atcgtggaaa atggtaagaa gattaccttc cttgatacac caggacacgc
     9901 ggcctttaca tcaatgcgtg cgcgtggtgc ttctgttacc gatattacga tcttggtcgt
     9961 agcggcagat gacggggtta tgcctcagac tatcgaagcc attaaccact caaaagcggc
    10021 caacgttcca atcatcgtag ccattaacaa gattgataaa ccaggtgcta acccagaacg
    10081 cgttatcggt gaattggcag agcatggagt tatgtcaact gcttggggtg gagattctga
    10141 atttgttgaa atctcagcta aattcaacca aaatatcgaa gaattgttgg aaacagtcct
    10201 tcttgtagct gaaatccaag aactcaaggc agacccaaca gtgcgtgcaa tcggtacggt
    10261 tatcgaagcg cgcttggata aaggaaaagg tgcggtcgca acccttcttg tacaacaagg
    10321 taccttgaat gttcaagacc caatcgttgt cggaaatacc ttcggtcgtg tccgtgctat
    10381 gaccaacgac cttggtcgtc gtgttaaagt tgctggacca tcaacaccag tctctatcac
    10441 aggtttgaac gaagcaccga tggcgggtga ccactttgcc gtttacgagg atgaaaaatc
    10501 tgcgcgtgca gcaggtgaag agcgtgccaa acgtgccctc atgaaacaac gtcaagctac
    10561 ccaacgtgtt agccttgaaa acctctttga tacccttaaa gctggggaac tcaaatctgt
    10621 taatgttatc atcaaggctg atgtacaagg ttctgttgaa gccctttctg cctcacttca
    10681 aaagattgac gtggaaggcg tcaaagtgac tatcgtccac tcagcggtcg gtgctatcaa
    10741 cgaatcagac gtgacccttg ccgaagcttc aaatgccttt atcgttggtt tcaacgtacg
    10801 ccctacacca caagctcgtc aacaagcaga agctgacgat gtggaaatcc gtcttcacag
    10861 cattatctac aaggttatcg aagagatgga agaagctatg aaagggatgc ttgatccaga
    10921 atttgaagaa aaagttattg gtgaagcggt tatccgtgaa accttcaagg tgtctaaagt
    10981 gggaactatc ggtggattta tggttatcaa cggtaaggtt gcccgtgact ctaaagtccg
    11041 tgttatccgt gatggtgtcg ttatctatga tggtgaactc gcaagcttga aacactataa
    11101 agacgacgtt aaggaagtta caaacggccg tgaaggtgga ttgatgatcg acggctacaa
    11161 tgatattaag atggatgatg tgattgaggc gtatgtcatg gaagaaatca agagataaga
    11221 ttttttgctc ctttcttagg tggtgaggga cgcaagcaaa ccgatggttt cattgcttat
    11281 ttttgagcct agggtctcaa aaatcccccg tgatgggact gataaatcag ttccatcact
    11341 ttcaccacgg cgaaagaagc agatgacttc aaattgaact tcgtttcaat ttaaactgaa
    11401 aatcaagaag tttaaaatag ctaggtctgc tggcctagct tttggttcaa agtagagaaa
    11461 ggaatatcat ggcaaatcat ttccgtacag atcgtgtggg catggaaatc aagcgtgaag
    11521 tcaatgagat tttgcaaaag aaagtccgtg atccacgtgt ccaaggtgtg accatcacag
    11581 atgttcagat gctgggtgac ttgtctgttg ccaaggttta ttacaccatt ttgagtaacc
    11641 ttgcttcgga taaccaaaaa gcccaaatcg ggcttgaaaa agcaactggt accatcaaac
    11701 gtgaacttgg tcgcaatttg aaattgtaca aaatcccaga tttgaccttc gtcaaagacg
    11761 agtccatcga gtatggaaac aagattgacg agatgctacg caatctggat aagaactaaa
    11821 gaagaggggt tgcccctctt ttttggtgga ggaaaatagg ttgaatttga aatggaaaaa
    11881 tattctttta taatagattg aaactagaat agtacgcctc tacttctaaa atattgttag
    11941 aaatcgattt gactgtcctg atcgatttgt cctgttcttg tttcatttta ctataaaaaa
    12001 ggggttctgt attttttaat gttatctaat tagaaaatgc tttttttgta ggaaatataa
    12061 tatgataagg tgtaaaaaag aaataaggag tttgtatatg gctgaacaag acttagctat
    12121 gcaagtatta caacaagtgg taaaactacc agttgttaag gttgatcgtt cgaaattttt
    12181 agtggataag ttttccaaag aattgggtcc acaggacatt cctaccttat tggaacaagg
    12241 tccaacgtct ctcttatctc aagaaatctt agatcgagtg gctaatgcct gtattaggga
    12301 taatgtttta ttagcgagtg ggacttctgt tttggcagga ttacctggag ggcttgctat
    12361 ggcaattacc attccagctg atgtggctca attttatggt ttctctctga aattggccca
    12421 agaattaggt tatatttatg gttatgagga tctttgggct tcacgcgatg agttgagtga
    12481 agatgctcaa aatacccttt tgctttatct aggcgtcatg ttgggggtga atggaactgc
    12541 tgctttgcta cgtgctggtg gtataacaat tgccaaacag gtaatgaaaa cagtacctaa
    12601 taaagcttta acaaagacgc tttggtatct tattttgaaa aaagttttaa gaatatttgg
    12661 tgtgaatctt accaagggag ggctggccaa aggaatgggg aaatttattc ctatcttggg
    12721 tggtatcatt tcaggtggtt taacctttgc aactatgaaa ccgatgggtg aaagcttgca
    12781 gaaagaattg tccaagctag ttaactatag tgaagttcaa tatcaagaag atgttgaaac
    12841 aatccgaaaa gaggctgaaa tcatcgaagg agagtaatat gggactcata aaaactctag
    12901 ctaaaattta tggtaattac tttttgaccg tgcaaggtgt aaaagtgatg aaaacgataa
    12961 agaaagatga ccatgtcgtt gttggtctgg gaaaactctt tattgcagat aagctaatgg
    13021 atacggctcg gtggctcatt aagccagagg agagagaatg aaattttttt ggtcttcttg
    13081 ctattctttt tatcaaaccg attattgaga ttgtgaaatt cttttggatg atcatttctt
    13141 ttgcagtcca attgctgttt tacaagatat tatttaagat attggattgg ctctttaaac
    13201 ttatctagat ggtaatccaa gtcgcagaga actagcagga actccactgc tagtttttta
    13261 ttctctttcc atatggtata atataagcag taaaatcatt ttatactctt cgaaaatctc
    13321 ttcaaaccac gtcagcttca ccttgctgta tatatgttac tgacttcgtc agttctatcc
    13381 acaacctcaa aacactgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt
    13441 ttcattgagt attagaacat acaatggagg tcgtcatgga caatatcatc gatgtgtcaa
    13501 ttcctgttgc agaagtggtg gacaagcatc cagaagtctt ggaaattcta gtggagttgg
    13561 gttttaaacc ccttgccaat cccttaatgc gcaatacagt tggtcgtaaa gtatcactta
    13621 aacagggttc taagctagca ggaactccta tggacaagat tgtacgcaca ctggaagcga
    13681 atggctacga agtgattgga ttagactaat ggcagatgaa cggattcatg tcctacggga
    13741 tattttatta gaattgcata atggcgcctc tcctgagtcg gttcaggagc gttttgatgc
    13801 gacctttgcg ggtgtctcag ccattgagat ttcccttatg gagcacgagc ttatgaactc
    13861 agactcaggt gtcacctttg aagatgttat ggaactctgt gatgtccatg ccaatctttt
    13921 taaaaatgct atcaaaggtg tcgaagtttc agatactgag catccaggtc acccagttcg
    13981 tgtctttaag gaagaaaatt tggccctccg tgcagctttg attcgcattc gtagattgtt
    14041 agatacctat gagttgatgg aagacgagga aatgcttgcg gagatgcgca agggcttggt
    14101 gcgtcagatg ggacttgtgg ggcaatttga catccattac caacgtaaag aagaactctt
    14161 ctttcctatc atggagcgct atggacacga ttcacctccc aaagttatgt ggggagtgga
    14221 tgatcagatt agggaactct ttcaaacagc tctaacgaca gccaagtcac taccagaagt
    14281 gtcaattagc agtgtaaagg aagtttttga agcttttgcg atagagtttg aaagtatgat
    14341 tttcaaggaa gagtccatcc tcctcatgat tctccttgag tcttttactc aggatgactg
    14401 gcttcagatt gcggaggaga gcgatgccta tggctatgcc atcatccgtc cgtcagagaa
    14461 atgggtgcca gaacgacaga gctttattga ggaaaagatt gcagaggagc ctgtacagct
    14521 agatacggca gaaggtcaag ttcaacaagt tatagatacg ccagaaggcc attttaccat
    14581 tacctttacc cctaaggaaa aggaagctgt gctggaccgc catagtcaac aggcttttgg
    14641 taatggctat ctttcagtcg agcaggccaa tctcatcctc aatcatctcc ctatggagat
    14701 tacctttgtc aataaagaag atattttcca gtattacaat gacaatacgc cagctgatga
    14761 gatgattttc aaacggacgc cgtcccaagt cgggcgcaat gtcgaactct gtcatccgcc
    14821 taagtatttg gacaaggtca aggctatcat gaagggactt cgtgagggga ccaaggacaa
    14881 gtatgaaatg tggttcaagt ctgagtcgcg aggcaagttt gtccacatca cctatgctgc
    14941 agtacacgat gaaaacggag aattccaagg tgtactggaa tacgttcagg atatccagcc
    15001 ctaccgtgag attgatacgg actattttcg tggattagaa taaggagaaa aaatgagtta
    15061 cgaacaagaa tttatgaagg aatttgaagc ttgggtcaat acccaaatca tgattaacga
    15121 catggcgcac aaggaaagcc aaaaagttta cgaagaagac caggacgagc gtgccaaaga
    15181 tgccatgatt cgctacgaga gtcgcttgga tgcttatcag ttcttgcttg gtaagtttga
    15241 aaacttcaaa gcaggcaagg gattccatga tttgccagaa ggcttgtttg gtgagcgaaa
    15301 ttattaaacg agaaagattc ttgatttttc actaaaatct tgatagaatg tttatgttaa
    15361 atccttgtca gagcagggat tttttattga aaggatttta tcatgtcaaa gaaactcaat
    15421 cgtaaaaaac aattacgaaa tggcctccgt cgcgcaggtg ccttttcaag tactgtgact
    15481 aaggttgtag atgagacaaa aaaagtcgtg aagcgtgcag aacagtcagc aagcgcagct
    15541 ggtaaggcag tttctaaaaa agttgaacaa gcagtagaag ctaccaaaga gcaagctcaa
    15601 aaagtagcta attctgtaga agattttgca gcaaacttgg gtggacttcc acttgatcgt
    15661 gccaagactt tctatgatga aggaatcaag tctgcttcag atttcaaaaa ctggactgaa
    15721 aaagaactcc ttgccttgaa aggaatcggc ccagctacca tcaagaaatt gaaagaaaat
    15781 ggcatcaagt tcaagtaatt tttcttgagc cttgcatttc cgagaaaaac ttgctacaat
    15841 agagccatta gaggtgtttt gaatcccaca ttttacagaa agtggcggtg ctgagaagtc
    15901 cacaaatgtg tcaaaactgg ttgctaatgg atgaaaaatt gaaataaaag tgtctttttg
    15961 ctttaaagac gagagttgcg ggcaactgcc cgaaattggg tggtaccgcg gataaataca
    16021 ttcgtccctg tcatgtagat ggcagggctt ttcttttgtg tcttagtcaa aggaggttgt
    16081 tataaaacaa tcatttaaaa ctaataaact atattatagt tttcctgttt ttattttagg
    16141 atatcaagat cagaattttg gctataacat tacgacctgt agttcctcgt atagtctagg
    16201 agattgggtt gtaattggag tcgttgcgag agagaatgcc gcagagcaga tcaaacagta
    16261 tcaaaaattt actgtgaata tttctgatga aacttctatg cttgcgatgg agcaggctgg
    16321 ttttatcagt catcaggaga aattggaacg tttgggagtg cattatgaaa tttctgaacg
    16381 aactcagact cctattttag acgcctgtcc acttgtttta gattgtcggg tagataggat
    16441 tgttgaggaa gacggtattt gccacatctt tgccaagatt cttgagcgac ttgttgcccc
    16501 agaactcctg gatgaaaagg gacattttaa aaatcaactg tttgccccaa cctatttcat
    16561 gggagatgta tatcagcgcg tttatcgcta tctggacaag cgtgtagata tgaagggcag
    16621 tttcatcaaa aaaagcgagg aagaaggatg gcaagaactg agctgccaga taaaatcgaa
    16681 acagaacgtc tcgttttacg agtccgtact gtggcggatg ctgaggatat ctttgactat
    16741 gctagtttgc cagaggtcgc ctatccagca ggttttcctc cagtcaagac cttggaagat
    16801 gagatttatt atctggagca cattcttccg gagcgtaatc aaaaggaaaa tctcccagca
    16861 ggctacggga ttgtcgtcaa aggaacggat aagatcgttg gctctgtcga tttcaaccat
    16921 cgccatgaag atgatgtgct ggaaatcggc tataccttac acccagacta ttgggggcga
    16981 ggttatgtgc cagaagctgc gcgtgccttg attgacttag cctttaaaga tttgggtctt
    17041 cacaagattg aactaacttg ctttggatat aaccttcaaa gtaaacgagt cgcggaaaag
    17101 cttggcttta ccctcgaagc tcgcataaga gaccgaaagg atgttcaagg aaaccgctgt
    17161 gacagtctga tatatggctt gctgaagagc gagtgggagg tgatttgatg catcttttca
    17221 tcattggtgc tccagcatca ggaaaaatga ccattggtca agaattatct cgactgacgg
    17281 atgctaccct attttataac catcaagcca ttgattttgc actagaaatc tatcaggact
    17341 atacagagga aatgtgggaa tttgttcgtg gaatcacttt ttcattcctt ggagcaagtg
    17401 caagaaatca gcgatcagta attttaacag atgtaattga tttttcaaat cagtatcatc
    17461 tgatatattt aaagcaaatt cagaatttgt tggatgatta tcatcaagag attctttttg
    17521 ttgagttgga aacaagtctt gaagagtgca tacgtcgaaa tcgaacggag aatcgattaa
    17581 agcacaaacc cttaaaacga catattgagg tatctgaaag agaaatttta gagaccgctg
    17641 aaacacttca attaaattcc caatatcaac cgaatgagtt gcaccactac tttaaaataa
    17701 ataatacgaa tttgtctgca gaagaagctg ctaagcagat tcaaaataaa ataaacaaaa
    17761 tagagaaagg acacacacat gtctaaagaa ctttcatcta aatacaatcc agccgaggtt
    17821 gaggctggtc gttaccaaaa atggcttgat gcggatgttt tcaagccttc aggcgatcaa
    17881 aaggctaagc cttattcaat cgtgattcca ccaccaaacg taactgggaa acttcacctt
    17941 ggtcacgctt gggatacgac tttgcaggat atcatcatcc gtcaaaaacg catgcagggc
    18001 tttgatacgc tttggcttcc aggtatggac cacgctggta ttgcgactca ggctaaggtt
    18061 gaggagcgct tacgtggtga gggtattacg cgttatgacc taggtcgtga gtctttcttg
    18121 acgaaggtct gggaatggaa agacgaatat gccactacca tcaaggaaca atggggcaag
    18181 atggggcttt ctgtagacta ttctcgtgag cgtttcactc ttgacgaagg tttgtcaaaa
    18241 gctgttcgta aggtctttgt ggacctttac aagaaaggct ggatctatcg tggtgagttt
    18301 atcatcaact gggacccagc agctcgcaca gccctttctg atattgaggt gattcacaag
    18361 gatgtagaag gtgccttcta ccacatgaat tacatgctgg aagatggttc acgcgccctt
    18421 gaagttgcta caactcgtcc tgagactatg tttggggacg ttgcggttgc ggttaatcca
    18481 gaagacccgc gctacaagga cttgattggt aaaaacgtca tccttccaat cgctaataaa
    18541 ctcatcccaa tcgttggaga tgagcacgca gatcctgagt ttggtactgg tgtcgtgaaa
    18601 atcacacctg cccacgatcc aaatgacttc ttggttggcc aacgtcataa cttgccacaa
    18661 gtcaacgtca tgaacgacga cggaactatg aatgagcttg cctttgaatt ttcaggcatg
    18721 gatcgttttg aagctcgtaa ggcagtcgtt gctaagttgg aagaaatcgg tgcccttgtc
    18781 aaaatcgaaa aacgtgtcca cagtgttggt cactcagaac gtacaggtgt cgtagttgag
    18841 ccacgcttgt ctactcaatg gttcgtcaag atggaccaat tggctaagaa cgccattgcc
    18901 aaccaagaca cagaggacaa ggtcgaattc tacccacctc gtttcaacga taccttcctt
    18961 caatggatgg aaaatgtcca cgactgggtt atctctcgtc agctctggtg gggtcaccaa
    19021 atccctgctt ggtacaatgc tgatggtgaa atgtatgtcg gcgaagaagc tccagaaggt
    19081 gacggatgga ctcaggacga agacgtcttg gatacttggt tcagttctgc cctctggcca
    19141 ttttcaacca tgggctggcc tgaagtcgac tcagaagact ttaaacgtta tttcccaact
    19201 tcaaccttgg taacaggtta cgacatcatc ttcttctggg tgtctcgtat gatcttccag
    19261 tcattggaat tcacaggccg tcaaccattc caaaacgtcc ttatccacgg tcttattcgt
    19321 gacgagcaag gacgcaagat gtctaagtct ctcggtaacg ggattgaccc aatggatgtt
    19381 atcgagaaat acggtgccga tgcccttcga tggttccttt caaacggttc tgcgccagga
    19441 caagacgtgc gtttctctta tgagaaaatg gatgcttcat ggaacttcat taacaagatc
    19501 tggaacatct ctcgctatat cctcatgaac aatggaggtt tgacgctgga tgtggcgcat
    19561 gacaatgtca caaaagttgc aacaggtgag gctggtaatg tgacggaccg ctggattctc
    19621 cacaatctca acgaaaccat tgcaaaagtt actgaaaact ttgataagtt cgagtttggt
    19681 gtggctggtc atatccttta caacttcatt tgggaagaat ttgccaactg gtatgttgag
    19741 ttgaccaagg aagttcttta cagcgacaat gaagacgata aggtcattac tcgatctgtt
    19801 ctcctctata cgctggataa aatccttcgt ctccttcact caataatgcc gttcgtgaca
    19861 gaagaaatct ttggtcagta cgctgaaggc tctatcgtga cagcagcata cccaactgtt
    19921 aatctagcct ttgaagacct tgcggctcac actggtgtgg aaagtctcaa agacttgatc
    19981 cgtgccgttc gtaatgcgcg tgcggaagta aatgtagcac caagcaagcc tatcaccatc
    20041 cttgttaaga caagcgatag cgacttggaa gccttcttta acagcaatgt caactatatc
    20101 aaacgcttta caaatccaga acacttggaa atcgcatcaa ccatccctgc acctgaactg
    20161 gctatgtcaa gtgtcatcac aggagcagaa atctacctgc cactggccga tctcctcaat
    20221 gtcgaagaag aattggcacg tctggaaaaa gaacttgcca aatggcagaa agaactggac
    20281 atggttggta agaaactctc taacgaacgc ttcgtagcca acgccaaacc agaagtcgtc
    20341 caaaaagaac gcgacaaaca agctgactac caagccaagt atgatgcgac cgtagcacgt
    20401 attgatgaga tgaagaagtt ggtgaaataa acacagaaac acggtgatga gccgtgtttt
    20461 ttggtataat gaaatcaata tctattgatg gagaaagtga tgtccaaaca ccctcattat
    20521 gaattgttaa atttaattgg ctacggtctt gccaagtttg acaagctttt tataaaagaa
    20581 tttcaatgct ctagcaagtc ggagttttat cgctatgtgg tttctctggg aattgctgaa
    20641 acaactggag ttgtaaaaaa tagaatggat ttatttgatc cttattttga caataatcga
    20701 aaaggttggt ggcagaaagc tgaagtttat cgttttcgta aagatttaat tgatatgatg
    20761 tttggaaatg aagatgttca tagttatgct gaaatagtta aaatgttact tgccagtgaa
    20821 gggaagaaaa caggcataac catcgttgaa aaaccaatag ttcgaactaa attcaaacgt
    20881 ctacaggaaa cgggaatgga ggctgagaat tattttatcc ttcattttga taaagaagaa
    20941 aaattccaag gtggacagtt aaccgatgcc cgtctttatg gtgatggata tgactttcag
    21001 gtagatgtcc aagagtattc ttaccttgcc gaagtaaaag gtatccgaaa atctaagggg
    21061 cgtgtgcgtt taactgcaaa agaatttgaa aaagtcaagg agtttcaatc ggattttatt
    21121 ttatccttgg tcacaaatct agatgatatt ccaaagttag tgttaatcga taatccttta
    21181 aaacattttg agtttaaaaa gaatattatc aaaaatgaaa tcattgaata tagaagcgta
    21241 gaggatttgt attagttccc ccttaacttt tccagttgaa ggaacgagaa gtcttgacag
    21301 gtcaacgact taatgaactg gaaatcaacg gtattcgttt gactaagttt taagatggcg
    21361 aaatcggtat tgaatttatc agtagtgctg attataactc ttttattatt tacatgaagt
    21421 atatatatat atcatagaac ctattgtgag gactttttat agtttaagcc agtttccaac
    21481 caatttcgtg atttactggt aatgaagaaa aacaattgaa aggatatttc tatgcaatca
    21541 acttacaaca ttgacaatcc aaacttgtct tatgaagcga agcgtgattt atggcggata
    21601 ggttttggtc tgcagaaagt tgacaatcta gtgccatcag cgtatatgga atctttggct
    21661 gagaaacagt cccggggaga actgacttat gagcaggttt atgagaatgc aacggcttat
    21721 caccatacta ttgatgcaag tacggaagag gcagacttgg tttctctacg tattgtagaa
    21781 ctattgtctc gaagaggctt tagctttagt cctgcgacct tacttgctat tcataaggag
    21841 ttgtttcaag atatatttga accctctatt ccggtggggc aatttcgtca gaccaatatc
    21901 acaaagaatg aacctgtttt gaatggtgaa agtgttgtgt actctgatta ctccatgatt
    21961 caaatgacct tagattatga ttttaatcag gaaaaacaag ttgcatatgc gacactaact
    22021 caggcggatg tggttaaaca aatccagcat tttatttcag gaatctggca gattcatcca
    22081 tttcgcgaag gaaacactcg gacagtaacg gtctttttga ttcagtatct tcgtgagttt
    22141 ggttttgata ttgataatac accatttcag caacattcca aatattttcg tgatgccttg
    22201 gtattagata atgcaaagat tttacagcga cgttctgagt ttttaacagc tttttttgaa
    22261 aatctcttgc tcggtggtca aaatgatttg tcttcagaaa aaatgtatct agatttagac
    22321 ctcgattttt cataatccaa atactgagta aacattgaat tttaggcaaa aatgaagtaa
    22381 atattctcac aagaaaacgt atatcatcaa agttttaggt gtactgaccc caaaaagtta
    22441 gacaaataat ttatccgaag gatttagttc tgtattgcac aaggctaagt ccttttagtt
    22501 ttaccttaat tcgtttattg ttgtagtaat caatatagtc tacaatagct tgttccaatt
    22561 gattaagtga tttaaatgtt ttctcatagc cataaaacat ttccgatttc agaatcccaa
    22621 agaaggactc catcataccg ttgtcttggc tgtttccctt gcgtgacata gatgcttgaa
    22681 ttcccttact cttaggaacc gatgataaga atcgtgtcgg tattgccagc cttggtcact
    22741 atggagaatc gtattctcgt agtgcttctc tgtgaatgcc tgttccaaca ttgtttgtac
    22801 ttgttctaag ttgggtgaag ttgaaagatt ataggcgata atttcgctgt taaagccatc
    22861 taaaactggt gataagtaaa gcttttgagt acttgctgga atggcaaatt ctgtcacatc
    22921 tgtgtagcac ttttccattg ttttagatcc ttcaaattgg ccttgaatga gattctctgc
    22981 cttcttacca acgtctcct
//
LOCUS       DBEJZV010000029        22527 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.29, whole genome shotgun sequence.
ACCESSION   DBEJZV010000029 DBEJZV010000000
VERSION     DBEJZV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22527
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.29"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..225
                     /locus_tag="ACL3S0_001561"
     CDS             <1..225
                     /locus_tag="ACL3S0_001561"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312447.1"
                     /translation="GFTHYKYYRAFLISFGIPINIEITYLSIDGLVLVVTFQFINQKC
                     DGFIVYETASKIKKNLSSQFFYARLVKIKF"
     gene            239..808
                     /locus_tag="ACL3S0_001562"
     CDS             239..808
                     /locus_tag="ACL3S0_001562"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1312448.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGKFIGTIDLHKIDPVLKKVAIGYI
                     INQTYWNQGLTTETNRAVIELAFEKIGMNKLVALYDKANPASGKVMEKSGMRFSHAEP
                     YACMYQHEKGRIVTRVHYVLTKEDYFANK"
     gene            876..1526
                     /locus_tag="ACL3S0_001563"
     CDS             876..1526
                     /locus_tag="ACL3S0_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR1312449.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVHK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEESVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            1510..3750
                     /locus_tag="ACL3S0_001564"
     CDS             1510..3750
                     /locus_tag="ACL3S0_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGR1312450.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GYLNTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            3929..4117
                     /locus_tag="ACL3S0_001565"
     CDS             3929..4117
                     /locus_tag="ACL3S0_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312451.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHGHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            4150..4737
                     /locus_tag="ACL3S0_001566"
     CDS             4150..4737
                     /locus_tag="ACL3S0_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1312452.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            4741..5925
                     /locus_tag="ACL3S0_001567"
     CDS             4741..5925
                     /locus_tag="ACL3S0_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312453.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVNLNWSMGMVLLPCLIIFLLVGILFIESWGSSRKKEVFN
                     RS"
     misc_feature    6086..6217
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            6233..6763
                     /gene="infC"
                     /locus_tag="ACL3S0_001568"
     CDS             6233..6763
                     /gene="infC"
                     /locus_tag="ACL3S0_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGR1312454.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            6796..6996
                     /gene="rpmI"
                     /locus_tag="ACL3S0_001569"
     CDS             6796..6996
                     /gene="rpmI"
                     /locus_tag="ACL3S0_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGR1312455.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            7048..7407
                     /gene="rplT"
                     /locus_tag="ACL3S0_001570"
     CDS             7048..7407
                     /gene="rplT"
                     /locus_tag="ACL3S0_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGR1312456.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            7465..7845
                     /locus_tag="ACL3S0_001571"
     CDS             7465..7845
                     /locus_tag="ACL3S0_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR1312457.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            8095..8895
                     /locus_tag="ACL3S0_001572"
     CDS             8095..8895
                     /locus_tag="ACL3S0_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGR1312458.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSSLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            8858..9844
                     /locus_tag="ACL3S0_001573"
     CDS             8858..9844
                     /locus_tag="ACL3S0_001573"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGR1312459.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            9886..12051
                     /gene="lytB"
                     /locus_tag="ACL3S0_001574"
     CDS             9886..12051
                     /gene="lytB"
                     /locus_tag="ACL3S0_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGR1312460.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAA
                     YYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQ
                     ALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLE
                     NPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHS
                     ALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGR
                     TFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(12112..13767)
                     /gene="pavA"
                     /locus_tag="ACL3S0_001575"
     CDS             complement(12112..13767)
                     /gene="pavA"
                     /locus_tag="ACL3S0_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGR1312461.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            13872..14369
                     /gene="ybeY"
                     /locus_tag="ACL3S0_001576"
     CDS             13872..14369
                     /gene="ybeY"
                     /locus_tag="ACL3S0_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGR1312462.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRNTDRPTDVISLEYKPELEIAFDEEDLLENSELAEMMSEFDAYIGEL
                     FISSDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            14350..14745
                     /locus_tag="ACL3S0_001577"
     CDS             14350..14745
                     /locus_tag="ACL3S0_001577"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR1312463.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            14762..15661
                     /gene="era"
                     /locus_tag="ACL3S0_001578"
     CDS             14762..15661
                     /gene="era"
                     /locus_tag="ACL3S0_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGR1312464.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            15710..16534
                     /gene="mutM"
                     /locus_tag="ACL3S0_001579"
     CDS             15710..16534
                     /gene="mutM"
                     /locus_tag="ACL3S0_001579"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGR1312465.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLNQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            16534..17139
                     /gene="coaE"
                     /locus_tag="ACL3S0_001580"
     CDS             16534..17139
                     /gene="coaE"
                     /locus_tag="ACL3S0_001580"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGR1312466.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            17126..18325
                     /locus_tag="ACL3S0_001581"
     CDS             17126..18325
                     /locus_tag="ACL3S0_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGR1312467.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            18325..18474
                     /gene="rpmG"
                     /locus_tag="ACL3S0_001582"
     CDS             18325..18474
                     /gene="rpmG"
                     /locus_tag="ACL3S0_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR1312468.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            18514..18747
                     /gene="secG"
                     /locus_tag="ACL3S0_001583"
     CDS             18514..18747
                     /gene="secG"
                     /locus_tag="ACL3S0_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGR1312469.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            18849..21203
                     /gene="rnr"
                     /locus_tag="ACL3S0_001584"
     CDS             18849..21203
                     /gene="rnr"
                     /locus_tag="ACL3S0_001584"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGR1312470.1"
                     /translation="MKDRIKEYLQDKGKMTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVLSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            21166..21633
                     /gene="smpB"
                     /locus_tag="ACL3S0_001585"
     CDS             21166..21633
                     /gene="smpB"
                     /locus_tag="ACL3S0_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGR1312471.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            21649..22509
                     /gene="tehB"
                     /locus_tag="ACL3S0_001586"
     CDS             21649..22509
                     /gene="tehB"
                     /locus_tag="ACL3S0_001586"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGR1312472.1"
                     /translation="MEKSVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
BASE COUNT         6726 a         4091 c         5134 g         6576 t
ORIGIN      
        1 ggatttaccc actacaaata ttatagagcc tttttaattt cttttgggat tccgattaac
       61 attgagataa cctacctttc aattgacggt cttgttttgg ttgtcacatt ccagttcata
      121 aatcaaaaat gtgacggttt cattgtatat gaaaccgctt caaaaatcaa gaaaaacttg
      181 tcatcccaat ttttttatgc tagactagtg aaaatcaagt tctaatggag ggaaaagtat
      241 ggaatcaatt tttgtaaaac ttgcccagta tccgtctata gaaacggagc gtttattgct
      301 tagacctgta actttggatg atgcggaagc aatgtttgac tatgcctcgg acaagggtaa
      361 tacacgttac acttttccaa ccaatcaaag cttggaagaa accaagaata acattgctca
      421 gttctacttg gctaatccct tgggacgttg gggaatagaa ctaaaaagca atggcaaatt
      481 tatcggaaca attgatttgc acaagattga tcctgttctt aagaaggtag ctattggtta
      541 tattatcaac caaacgtatt ggaatcaagg attaacgaca gaaaccaatc gtgctgtgat
      601 tgagctagct tttgagaaga taggaatgaa taagttagtt gctttatacg ataaggctaa
      661 tcccgcatca ggaaaggtca tggagaaatc aggaatgcgt ttttcccatg cagaaccata
      721 tgcttgtatg taccagcatg aaaaaggccg aatcgtgaca agagttcatt atgtcttgac
      781 caaggaagac tattttgcaa ataaataagc agttgaaaag aaatttttcg actgtttttt
      841 cttcctctta cgaataatct aagagaggag aaaatatgga agcaattatc gagaaaatca
      901 aagagtataa aatcatcgtc atctgtactg gtctgggctt gcttgtagga ggatttttcc
      961 tgctaaaacc agctccacaa acacctgtca aagagacgaa tttgcaggct gaagtcgcag
     1021 ctgtttccaa ggatttggta tccgaaaagg aagtgaacaa ggaagaaaag gaagaacccc
     1081 ttgaacaaga tctaatcaca gtagatgtca aaggtgctgt caaatcgcca gggatttatg
     1141 acttgcctgt aggtagtcga gtcaatgatg ctgttcataa ggctggtggc ttgacagagc
     1201 aagcagacag caagtcgctc aatctagctc agaaagttag tgatgaggct ctggtttacg
     1261 ttcctactaa gggagaagaa tcagttagcc aacagactgg tttggggaca gcttcttcaa
     1321 taagcaagga aaagaaggtc aatctcaaca aggccagtct ggaagaactc aagcaggtca
     1381 agggactggg aggaaaacga gctcaggaca ttatcgacca tcgtgaggca aatggcaagt
     1441 tcaagtcagt agacgagctc aagaaggtct ctggcattgg tggcaaaaca atagaaaagc
     1501 ttaaagacta tgttacagtg gattaagaat ttctctattc ccctaattta cctgagtttt
     1561 ctattacttt ggctttatta cgctattttc tcagcatctt atcttgcttt gttgggcttt
     1621 gtttttctgc tagtctgtct ctttatccaa tttccgtgga aatctgctgg taaagttcta
     1681 ataatttgcg gaatctttgg attttggttt gtttttcaaa attggcaaca gagtcaagtg
     1741 agtcaaaatt tggtggattc tgttgaaagg gtacggattt taccagacac tattaaggtt
     1801 aacggtgata gtctatcctt tcgtggcaag tctaacggtc gtgctttcca agtctattat
     1861 aaactccagt ccgaggagga gaaagaagcc tttcaagctt taaccgacct gcatgagata
     1921 ggactagaag ggaagctttc ggagccagaa gggcagagaa attttggtgg ctttaattac
     1981 caagcctatc tgaagactca gggaatttac cagactctca atatcaaaaa aatccagtca
     2041 cttcaaaaga ttggcagttg ggatatagga gaaaacttgt ccagtttacg tcgaaaggct
     2101 gtggtttgga ttaagacgca ctttccagac cctatgcgca attacatgac aggactcttg
     2161 ctgggatatc tgaacaccga ctttgaggag atgaatgagc tttattccag tctaggaatt
     2221 atccacctct ttgccctatc tggcatgcag gtaggttttt tcatgaatgg atttaagaaa
     2281 cttctcttgc gattgggctt gacccaagaa aagttgaaat ggctgactta tcccttttcc
     2341 cttatctatg cgggactaac tggattttca gcatcggtta ttcgcagtct cttgcaaaag
     2401 ctactggctc aacatggggt taagggcttg gataattttg ccttgacggt gcttgtcctc
     2461 tttattgtca tgccaaactt tttcttgaca gcaggaggag tcttgtcctg cgcttatgct
     2521 tttatcctga ccatgaccag caaagaaggg gaggggctca aggctgttgc tagtgaaagt
     2581 ctagtcatct ccttgggcat attgcccatt ctatccttct attttgcgga atttcaacct
     2641 tggtctatcc ttttgacctt tgtcttttcc tttctatttg acttgacctt cttaccgctc
     2701 ttgtctattt tatttgtcct ttcctttctc tatccagtca ttcagctgaa ctttatcttt
     2761 gaatggttag agggcattat tcgcttggtc tcgcaggtgg caaggagacc gcttgtcttt
     2821 ggtcaaccca acgcatggct tttaatctta ttgttaattt ccttggcttt ggtctatgat
     2881 ttgaggaaaa acattaaagg attaacagta ttgagtttat tgattacagg tctctttttc
     2941 cttaccaagt atccactgga aaatgaaatc accatgctgg atgtggggca aggagaaagt
     3001 attttcctac gggatgtaac tgggaaaacc attctcatag atgtaggtgg taaggcagaa
     3061 tcttataaga aaatcgaaaa atggcaagaa aagatgacga ccagcaatgc acagagaagc
     3121 ttgataccct atcttaaaag tcgaggagta gctaagattg accagctgat tttgacaaat
     3181 acggacaagg aacatgtcgg agatttgtta gaggtgacca aggctttcca tgtaggggag
     3241 attttagtat caaaaggcag tttgaagcag aagcaatttg tggtagaact acaggcgact
     3301 caaacaaagg tgcgtagtat gacagtaggg gagaacttgc ccatttttgg aagtcagtta
     3361 gaagttctat ccccaaggaa aatgggagat ggaggacacg atgataccct agttctgtat
     3421 gggaaattct tggataagca atttctcttc acgggaaatt tggaggagaa aggagagaag
     3481 gacttgctga agcactatcc agacttgaaa gtaaatgttt tgaaagctag ccaacatggc
     3541 aataaaaaat catcaagtcc agcctttcta gaaaaactca aaccagagct tactcttatc
     3601 tcagttggaa agagcaatcg aatgaaactc ccccatcagg aaacattgac acgactggaa
     3661 ggtatcaata gcaaagttta ccgaactgac cagcaaggag ctatacgctt taaggggttg
     3721 gatagttgga aaatcgaaag tgttcgatag gaaagataaa tgttgtagat tagtgaaata
     3781 aactaaaaat ttgttgcata ataatgataa aaatggtata atgaaaacgt attcaatatt
     3841 gaggatataa aatcattaaa aattagcaaa aatcgtttaa ttagttagtt tataatctat
     3901 tggtcttctt cagtccagtg tatctgctgt gacagtcact aaaagttaca agtatgattg
     3961 gaatacggtt tgggaatata gtaccaacta tcacggccat cagtatgctt ggattccgtc
     4021 atggtctcgt tatgacagct attctgagta taaagttggc ggaggctgga actacggtcg
     4081 ttatgaggtc ataaactatt acagcggagg ctattaattc ttaaagagtg agaaaaagga
     4141 gggctagata tgttgcagct tactcatgtg accttaaaaa cgcgacaagt catcttgcaa
     4201 gatgcggatt ttacctttaa aaagggtagg atttatggcc ttcttgctat caatggctcg
     4261 ggaaagacga cactattccg agctatgagc aagttgcttc cccttagtag tggacacatc
     4321 gcagttcctc cttctttgtt ttattatgag agcgttgaat ggctggatgg aaacttaagt
     4381 gggatggact accttcgtct cataaaaaac atctggaagt cagacctaaa cttgagagat
     4441 gaaatcgcct actgggaaat ggctgactat atcagtcttc ccatccgcaa gtattcctta
     4501 ggcatgaagc aacgcttggt gattgctatg tattttctca gtcaggccaa atgctggctc
     4561 atggatgaga ttacaaatgg cttagacgag tattatcgac agaagttttt tgataggcta
     4621 gcacaaatcg atagacaaga acagctggtt cttttaagtt cccactataa ggaagagttg
     4681 gttgatatct gcgatagagt agtaaccatt catcaggggc agatagaaga ggtttagttt
     4741 atgaaagatg ttagtctatt tttattgaaa aaagttttca aaagtcgttt aaactggatt
     4801 atcttacttt tatttgcatc tgtactcggt gttacctttt atttaaatag tcagactgca
     4861 aactcacaca gcttggagag caggttggaa agtcgcattg cagccaacga gagggctatc
     4921 aatgaaaatg aagagaaact ctcccaaatg tctgatacca gctcggagga ataccagttt
     4981 gctaaaaata atttagacgt gcaaaaaaat cttttgacgc gaaagacaga aattctaact
     5041 ttactaaaag aagggcgctg gaaagaagcc tactatctgc agtggcaaga tgaagagaag
     5101 aattatgaat ttgtatcaaa tgacccgact gctagctctg gcttaaaaat gggggttgac
     5161 cgcgaacgga agatttacca agccctgtat cccttgaaca taaaagcaca tactttggag
     5221 tttccgaccc acgggattga tcagattgtc tggattttag aggttatcat cccaagcttg
     5281 tttgtggttg cgattatttt tatgctaaca caactatttg cagaaagata tcaaaatcat
     5341 ctggacacag ctcacttata tcctgtttca aaagtgacat ttgcaatatc ctctcttgga
     5401 gttggagtgg gatatgtaac tgtgctgttt atcggaatct gtggcttttc ttttctagtg
     5461 ggaagtctga taagtggttt tggacagtta gattatccct acccaattta tagcttagtg
     5521 aatcaagaag taactattgg gaaaatacaa gatgtattat ttcctggctt gctcttagct
     5581 ttcttagcct ttatcgtcat tgtggaagtt gtgtacttga ttgcttactt tttcaagcaa
     5641 aaaatgcctg tcctctttct ttcactcatt gggattgttg gcttattgtt tggcatccaa
     5701 accattcagc ctcttcaaag gattgcacat ctgattccct ttacttactt gcgttcagtg
     5761 gagattttat ctggaagatt acctaagcaa attgataatg tcaatctaaa ttggagcatg
     5821 ggaatggtct tacttccttg cctgattatc tttttgctag tggggattct atttattgaa
     5881 agctggggaa gttcacgtaa aaaggaagtt tttaataggt cttagcattc ttataaggaa
     5941 gttaaggaaa aactaacata gagagggaat caacttgatt ctctcttttt gattcgaaaa
     6001 ccaaaccaaa atacaaacac aaacttttca aaaaaataac tttttatctt gacaagagct
     6061 agaaaacttg gtatcattta aaagttgaga aaagcagaag tgagagcttc tcgccttgtg
     6121 acattaagtt gcctggccct acggatgaaa agtttcgaag aaacgctatc ataacgtgcg
     6181 ggcttgtata tttacgagtc cgctattgtt tttctctaat aaaacaaaag aggtgaaaac
     6241 catagcaaag caagacttat tcatcaatga tgagattcgt gtacgtgaag ttcgcttgat
     6301 tggtcttgag ggagaacagc taggcatcaa gccactcagt gaagcgcaag ctttggctga
     6361 taacgctaat gttgacctag tattgattca accccaagcc aaaccgcctg ttgcaaaaat
     6421 tatggactac ggtaagttca aatttgagta ccagaagaag caaaaagaac aacgtaaaaa
     6481 acaaagcgtt gttactgtga aagaagttcg tctaagtcca acaattgaca agggtgactt
     6541 tgatacaaaa cttcgtaatg cacgtaagtt ccttgaaaaa ggaaataaag ttaaggtatc
     6601 tattcgcttt aagggtcgta tgattaccca taaagagatt ggtgcaaaag ttttagccga
     6661 gtttgctgaa gcaactcaag atattgccat catcgaacaa cgtgctaaaa tggatggacg
     6721 tcaaatgttc atgcaattgg cgccagcgac tgacaaaaaa taattgtcag aaagttaaat
     6781 aaaggagaaa aaatcatgcc aaaacaaaaa acacaccgcg catcagctaa acgtttcaaa
     6841 cgtacaggtt ctggtggact taaacgtttc cgtgcttaca cttctcaccg tttccacgga
     6901 aaaactaaga aacaacgtcg tcatcttcgt aaagcatcta tggtgcattc aggagattac
     6961 aaacgtatca aagcaatgct tactcgcttg aaataatagc ttgactgtaa gtaaacaatt
     7021 ctaggaaata tttggaggaa ataaaacatg gcacgtgtta aaggtggcgt tgtatcacgc
     7081 aaacgtcgta aacgtattct taaattagca aaaggttact atggagctaa acacatcttg
     7141 ttccgtactg caaaagaaca agtaatgaac tcttactact atgcataccg tgaccgtcgt
     7201 cagaaaaaac gtgacttccg caaattgtgg attactcgta tcaatgcggc agctcgtatg
     7261 aacggacttt catactcaca attgatgcat ggtttgaaat tggctgagat cgaagttaac
     7321 cgtaaaatgc ttgctgactt ggctgttaac gatgcagtag ctttcacagc tcttgcagat
     7381 gcagctaaag caaaacttgg taaataacaa ctgatgagac tggaacagga ttgtccagtc
     7441 tttttaaaaa taaaggagaa agatatggct tcaaaaatgc tacacacttg cttacgagta
     7501 gaaaatcttg aaaaatcaat cgcattttat caagatgctt ttggttttaa agaattgcgt
     7561 cgcagagatt ttccagacca tgccttcacg attgtctatc taggtcttga gggtgatgat
     7621 tatgagttgg agttgactta taactacgat cacggtccgt atgtggttgg tgatgggttt
     7681 gcccatatcg ccctcagtac acctgatctt gaggcacttc atcaagaaca cagtgcaaaa
     7741 ggctatgaag tgactgagcc aaatggtcta ccaggaacta caccaaacta ttactttgtc
     7801 aaagaccctg atggatataa ggtcgaagtc attcgtgaaa aataatttcg tgcaagttaa
     7861 gtagaatatt cgttttctac ttgacttttt ttagctgaaa gagtatacta ataaaaattc
     7921 aacctttaag gggagtccag agagactcac aaggtgtcag ataaaagaat agtgcaattt
     7981 tctagaggag actttttgag tgtgctctct tgtgttgtac gattttaact gaggccttgc
     8041 actagcaagg tcttttcttt atctggtccc cttaaaattt aaggaggaaa agttatgaat
     8101 cccacatgta agaagcgttt gggtgtcatt cggttggaaa ccatgaaggt ggttgcacaa
     8161 gaggaaatcg cgccagcaat ctttgaatta gtcctagaag gagaaatggt tgaagccatg
     8221 cgagcaggcc aatttcttca tctgcgtgta ccagacgatg cccatctttt acgtcgtcct
     8281 atttcaattt cgtctattga caaggcaaac aagcagtgtc acctcattta tcggattgag
     8341 ggagctggga ctgcaatttt ttcaagctta agtcagggag acactcttga tgtgatgggg
     8401 cctcagggaa atggttttga cttgtctgac cttgatgagc agaatcaggt tctccttgtt
     8461 ggtggtggga ttggtgttcc acccttgctt gaggtggcca aggaattgca tgaacgtgga
     8521 gtgaaagtag tgacagtcct cggttttgct aataaggatg ctgttatttt gaaaacggaa
     8581 ttggctcagt atggtcaggt ctttgtaacg acagatgatg gttcttatgg catcaaggga
     8641 aatgtttccg ttgttatcaa tgatttagat agtcagtttg atgctgttta ctcgtgtggg
     8701 gctccaggaa tgatgaagta tatcaatcaa acctttgatg atcacccaag agcctattta
     8761 tctctggaat ctcgtatggc ttgtgggatg ggagcttgct atgcctgtgt tctaaaagta
     8821 ccagaaagcg agacggtcag ccaacgcgtc tgtgaagatg gtcctgtttt ccgcacagga
     8881 acagttgtat tataaggaga aaattatgac tacaaatcga ttacaagtgt ctctacctgg
     8941 tttggatttg aaaaatccga ttattccagc atcaggttgt tttggttttg gacaagagta
     9001 tgccaagtac tatgatttaa accttttagg ttctattatg atcaaggcga caacccttga
     9061 accacgtttt ggaaatccaa ctccaagagt ggcagagacg cctgctggta tgctcaatgc
     9121 aattggcttg caaaatcctg gtttagaggt tgttttggct gaaaagctac cttggctgga
     9181 aagagaatat ccaaatcttc ctattattgc caatgtagct ggtttttcaa aacaagagta
     9241 tgcagctgtt tctcatggga tttccaaggc aactaatgta aaagctatcg agctcaatat
     9301 ttcttgtccc aatgttgacc actgtaatca tggacttttg attggtcaag atccagattt
     9361 ggcttatgat gtggtgaaag cagctgtgga agcctcagaa gtgccagttt atgtcaaatt
     9421 aaccccgagt gtgaccgata tcgttactgt cgcaaaagct gcagaagatg cgggagcaag
     9481 tggcttgacc atgatcaata ctctggttgg aatgcgcttt gacctcaaaa ccagaaaacc
     9541 aatcttggcc aatggaacag gtggaatgtc aggtccagca gtctttccag tagccctcaa
     9601 actcatccgc caagtagccc aaacaacaga cctgcctatc attggaatgg ggggagtgga
     9661 ttcggctgaa gctgccctag aaatgtatct ggctggggca tctgctatcg gagttggaac
     9721 agctaacttt accaatcctt atgcctgccc tgacatcatc gaaaatttac caaaagtcat
     9781 ggataaatac ggtattagca gtctggaaga actccgtcag gaagtaaaag agtctctgag
     9841 gtaaactaca atcaatctgt tcttgatttt ttattagttt gtaatatgaa tttaggagaa
     9901 ttttggtaca ataaaataaa taagaacaga ggaagaaggt taatgaagaa agtaagattt
     9961 atttttttag ctctgctatt tttcttagct agtccagagg gtgcaatggc tagtgatggt
    10021 acttggcaag gaaaacagta tctgaaagaa gatggcagtc aagcagcgaa tgagtgggtt
    10081 tttgatactc attatcaatc ttggttctat ataaaagcag atgctaacta tgctgaaaat
    10141 gaatggctaa agcaaggtga cgactatttt tacctcaaat ctggtggcta tatggccaaa
    10201 tcagaatggg tagaagacaa gggagccttt tattatcttg accaagatgg aaagatgaaa
    10261 agaaatgctt gggtaggaac ttcctatgtt ggtgcaacag gtgccaaagt aatagaagac
    10321 tgggtctatg attctcaata cgatgcttgg ttttatatca aagcagatgg acagcacgca
    10381 gagaaagaat ggctccaaat taaagggaag gactattatt tcaaatccgg tggttatcta
    10441 ctgacaagtc agtggattaa tcaagcttat gtgaatgcta gtggtgccaa agtacagcaa
    10501 ggttggcttt ttgacaaaca ataccaatct tggttttaca tcaaagaaaa tggaaactat
    10561 gctgataaag aatggatttt cgagaatggt cactattatt atctaaaatc cggtggctac
    10621 atggcagcca atgaatggat ttgggataag gaatcttggt tttatctcaa atttgatggg
    10681 aaaatagctg aaaaagaatg ggtctacgat tctcatagtc aagcttggta ctacttcaaa
    10741 tccggtggct acatggcagc caatgaatgg atttgggata aggaatcttg gttttacctc
    10801 aagtttgatg gcaaaatggc tgaaaaagaa tgggtctacg attctcatag tcaagcctgg
    10861 tactacttca aatccggtgg ttacatgaca gccaatgaat ggatttggga taaggaatct
    10921 tggttttatc tcaaatctga tgggaaaata gctgaaaaag aatgggtcta cgattctcat
    10981 agtcaagctt ggtactactt caaatccggt ggttacatga cagccaatga atggatttgg
    11041 gataaggaat cttggtttta cctcaagtct gatggcaaaa tggctgaaaa agaatgggtc
    11101 tacgattctc atagtcaagc ctggtactac ttcaaatctg gtggctacat ggcgaaaaat
    11161 gagacagtag atggttatca gcttggaagc gatggtaaat ggcttggagg aaaagctaca
    11221 aatgaaaatg ctgcttacta tcaagtagtg cctgttacag ccaatgttta tgattcagat
    11281 ggtgaaaagc tttcctatat atcgcaaggc agtgtcgtat ggctagataa ggatagaaaa
    11341 agtgatgaca agcgcttggc tattactatt tctggtttgt caggctatat gaaaacagaa
    11401 gatttacaag cgctagatgc tagtaaggac tttatccctt attatgagag tgatggccac
    11461 cgtttttatc actatgtggc tcagaatgct agtatcccag tagcttctca tctttctgat
    11521 atggaagtag gcaagaaata ttattcggca gatggcctgc attttgatgg ttttaagctt
    11581 gagaatccct tccttttcaa agatttaaca gaggctacaa actacagtgc tgaagaattg
    11641 gataaggtat ttagtttgct aaacattaac aatagccttt tggagaacaa gggcgctact
    11701 tttaaggaag ccgaagaaca ttaccatatc aatgctcttt atctccttgc ccatagtgcc
    11761 ctagaaagta actggggaag aagtaaaatt gccaaagata agaataattt ctttggcatt
    11821 acagcctatg atacgacccc ttacctttct gctaagacat ttgatgatgt ggataaggga
    11881 attttaggtg caaccaagtg gattaaggaa aattatatcg ataggggaag aactttcctt
    11941 ggaaacaagg cttctggtat gaatgtggaa tatgcttcag acccttattg gggcgaaaaa
    12001 attgctagtg tgatgatgaa aatcaatgag aagctaggtg gcaaagatta gtactataag
    12061 tgaatatgat ttgagtgaat agtaagttaa aaatcctgat ttcaagtaaa atcaggattt
    12121 tttcatggat gcaatttttt tggagtctgg tgtgacgcgg agggtctttt gtcctgtgta
    12181 agtgacaaag ccgggttttc caccagttgg tttattgagt tttttgactt caatcatatc
    12241 tacctgcacc agattcgaca ggcgcccttg agagaagtag gcagctaact ctgctgcgtc
    12301 tgtcttgact gcatcagatg ggtcaagatt tcctgagatg acaacatggc ttccaggaat
    12361 gtccttagca tggaaccaaa gttcctcctt gcgggccatt ttaaaggtca attcctcatt
    12421 ttgaagattg tttcgtccga catagatgat ggttttgcca tcgcttgcta gatattgttc
    12481 tagttttttg cgtttctgga ttttctcccg ttgtcttctg cggataaaac ctgtttgaat
    12541 caattcttca cggatttcag cgatttcttc cagtccagct tggttgagga cggtttctac
    12601 actttccaga tagagaatag tggctttggt ttcttcaatc aaatcagtca agtatttgac
    12661 agcttctttg agtttctgat accgtttaaa atagcgttgg gcattctggt tgggagtcag
    12721 agccttatca agcgcaatca tgataggttg gttggtatag tagttgtcta ggataacctg
    12781 gtcttggtcg ttaggcactt ggtgtaggaa ggttgtcagc aattctcctt tttgacgaaa
    12841 ttcttcagcg ttgtctgtcg ccagtaactc tttttcctgt tttttgagtt tgtgtcggtt
    12901 tttctgaagt tcattttcaa cacgacgaat cagttcactg gcctgctgtt tgacgcggtc
    12961 gcgctcagcc ttatccttat agtaggtgtc caacaaatca gaaagatttg caaaaggctc
    13021 tcccacctga tttgcaaaag gaactggact gaaggaagtc tcagtcaagc atggcttggt
    13081 ttcttgattg aaaaaatttc ggaaagcgga aagtttttca ctaaccagta tcctttccaa
    13141 ttcatttgcc gtatcgcgtc ccagaccttg aaagaggctt tgaagatttt ttgctgttag
    13201 ttcttgggtt tgcaggattt caaagagctt ttcatccttg atagtaaaag gattgagaga
    13261 ttctgtactt ggcggagcga tataggtcga tcctggaagt aaggtgcggt agctattttg
    13321 tgaaaaaccg acgtgtttga taacttcgag gattttatga ctgcttttat cgaccagtag
    13381 aatattactg tgtttcccca taatttcgat aatcaaggta gcctggatat ggtctccaat
    13441 ctcgttttta ttggaaactg taatttccac aatacggtca ttttccactt gctcaatcga
    13501 ctcaatcagg gccccctgca aatactttct caaaaccatg ataaaggtag aaggttgagc
    13561 tggattttca aaagtcgttt gggtcagctg aatgcgtcca aaaactggat gggcagaaag
    13621 gagcaggcga tggctttggc gattgctgcg gatttgcaag accaactctt gttcaaaagg
    13681 ctgattgatt ttctggatgc gaccattcac taattcgctt cgcaattcct caactatgtg
    13741 gtgtaaaaaa aatccgtcaa atgacatcgt tctctccttg tgattgtatt ccatagtatt
    13801 atatcaaaaa ggtagaataa aatcatggaa atgtggtata ataaagccaa gtaaagagaa
    13861 acgagaagca catgtatatt gaaatggtag atgaaactgg tcaagtttca aaagaaatgt
    13921 tgcaacaaac ccaagaaatt ttggaatttg cagcccaaaa attaggaaaa gaagacaagg
    13981 agatggcagt cacttttgtg accaatgagc gtagtcatga acttaatctg gagtaccgta
    14041 acaccgaccg tccgacagat gtcatcagcc ttgagtataa accagaattg gaaattgcct
    14101 ttgacgaaga ggatttgctt gaaaattcag aattggcaga gatgatgtct gagtttgatg
    14161 cctatattgg ggaattgttc atctctagcg ataaggctca tgagcaggcc gaagaatatg
    14221 gtcacagctt tgagcgtgag atgggcttct tggcagtaca cggcttttta catattaacg
    14281 gctatgatca ctacactccg gaagaagaag cggagatgtt cggtttacaa gaagaaattt
    14341 tgacagccta tggactcaca agacaataaa cgaaaatgga aaaatcgtga cctgatatcc
    14401 agtttagaat ttgccatcac agggattttt actgctatca aggaagaacg aaatatgcga
    14461 aaacatgcag tgacggctct agtggtcatc cttgcaggtt ttgtttttca ggtgtcacga
    14521 atcgaatggc tctttctcct attgagcatt ttcttggtag tagcctttga gattatcaac
    14581 tctgctattg aaaatatggt ggatttggcc agtcactatc acttttccat gctggctaaa
    14641 aatgccaagg atatggcggc tggcgcggta ttagtggttt ctcttttcgc agccttaaca
    14701 ggtgcattga tttttctccc acgaatctgg gatttattat tttaaacagt aagaggaaat
    14761 tatgactttt aaatcaggct ttgtagccat tttaggacgt cccaatgttg ggaagtcaac
    14821 ctttttaaat cacgttatgg ggcaaaagat tgccatcatg agtgacaagg cgcagacaac
    14881 gcgcaataaa atcatgggaa tttacacgac tgataaggag caaattgtct ttatcgacac
    14941 accagggatt cacaaaccta aaacagctct cggagatttc atggttgagt ctgcctacag
    15001 tacccttcgc gaagtggaca ccgttctttt catggtgcct gctgatgaag cgcgtggtaa
    15061 gggggacgat atgattatcg agcgtctcaa ggctgccaag gttcctgtga ttttggtggt
    15121 gaataaaatc gataaggtcc atccagacca gctcttgtct cagattgatg acttccgtaa
    15181 tcaaatggac tttaaggaaa ttgttccaat ctcagccctt cagggaaata acgtgtctcg
    15241 tctagtggat attttgagtg aaaatctgga tgaaggtttc caatatttcc cgtctgatca
    15301 aatcacagat catccagaac gtttcttagt ttcagaaatg gttcgcgaga aagtcttgca
    15361 cctaactcgt gaagagattc cgcattctgt agcagtagtt gttgactcta tgaaacgaga
    15421 cgaagagaca gacaaggttc acatccgtgc aaccatcatg gtcgagcgcg atagccaaaa
    15481 agggattatc atcggtaaag gtggcgctat gcttaagaaa atcggtagta tggcccgtcg
    15541 tgatatcgaa ctcatgctag gagacaaggt cttcctagaa acctgggtca aggtcaagaa
    15601 aaactggcgc gataaaaagc tagatttggc tgactttggc tataatgaaa gagaatacta
    15661 agtagaggta ggctcatgcc tgcttcttgt ttttacagaa ggaggactta tgcctgaatt
    15721 acctgaggtt gaaaccgttt gtcgtggctt agaaaaattg attataggaa agaagatttc
    15781 gagtatagaa attcgctacc ccaagatgat taagacggat ttggaagagt ttcaaaggga
    15841 attgcctagt cagattatcg agtcaatggg acgtcgtgga aaatatttgc ttttttatct
    15901 gacagacaag gtcttgattt cccatttgcg gatggagggc aagtattttt actatccaga
    15961 ccaaggacct gaacgcaagc atgcccatgt tttctttcat tttgaagatg gtggcacgct
    16021 tgtttatgag gatgttcgca agtttggaac catggaactc ttggtgcctg accttttaga
    16081 cgcctacttt atttctaaaa aattaggtcc tgaaccaagc gaacaagact ttgatttaca
    16141 ggtctttcaa tctgcccttg ccaagtccaa aaagcctatc aaatcccatc tcctagacca
    16201 gaccttggta gctggacttg gcaatatcta tgtggatgag gttctctggc gagctcaggt
    16261 tcatccagct agatcttccc agactttgac agcagaagaa gcgacagcta ttcatgacca
    16321 aaccattgct gttttgaacc aggctgttga aaaaggcggt tccaccattc ggacctatac
    16381 caatgccttt ggggaagatg gaagcatgca ggattttcat caggtctatg ataagactgg
    16441 tcaagaatgt gtacgctgtg gtaccatcat tgagaaaatt caactaggcg gacgaggcac
    16501 ccacttttgt ccaaactgtc aaaggaggga ctgatgagaa aaatcatcgg aatcactggg
    16561 ggaattgcct ctggtaagtc aactgtgaca aattttctaa gacagcaagg ctttcaagca
    16621 gtggatgccg acgcagtcgt ccaccaacta cagaaacctg gtggtcgtct gtttgaggct
    16681 ctagtacagc actttgggca agaaatcatt cttgaaaacg gagaactcaa tcgccctctc
    16741 ctagctagtc tcatcttttc aaatcctgaa gagcaaaaat ggtctaagca aattcaaggg
    16801 gagattatcc gtgaggaact ggctactttg agagaacagt tggctcagac agaagagatt
    16861 ttcttcatgg atattcccct actttttgag caggactaca gcgattggtt tgctgagact
    16921 tggttggtct atgtggaccg agatacccaa gtagaacgct taatgaaaag ggaccagttg
    16981 tccaaggatg aagctgagtc tcgtctggca gcccagtggc ctttagaaaa aaagaaagat
    17041 ttggccagcc aggttcttga taataatggc aatcagaacc agcttcttaa tcaagtgcat
    17101 atccttcttg agggaggtag gcaagatgac agagattaac tggaaggata atctgcgcat
    17161 tgcctggttt ggtaattttc tgacaggagc cagtatttct ttggttgtac cttttatgcc
    17221 catcttcgtg gaaaatctag gtgtagggag tgagcaagtc gctttttatg caggcttagc
    17281 aatttctgtc tctgctattt ccgcggcgct cttttctcct atttggggta ttcttgctga
    17341 caaatacggc cgaaaaccca tgatgattcg ggcaggtctt gctatgacta tcactatggg
    17401 aggcttggcc tttgtcccaa atatctattg gttaatcttt cttcgtttac taaacggtgt
    17461 atttgcaggt tttgttccta atgcaacggc actgatagcc agtcaggttc caaaggagaa
    17521 atcaggctct gccttaggta ctttgtctac aggcgtagtt gcaggtactc taactggtcc
    17581 ctttattggt ggctttatcg cagaattatt tggcattcgt acagttttct tactggttgg
    17641 tagttttcta tttttagctg ctattttgac tatttgcttt atcaaggaag attttcaacc
    17701 agtagccaag gaaaaggcta ttccaacaaa ggaattattt acctcggtta aatatcccta
    17761 tcttttgctc aatctctttt taaccagttt tgtcatccaa ttttcagctc aatcgattgg
    17821 ccctattttg gctctttatg tacgcgactt agggcagaca gagaatcttc tttttgtctc
    17881 tggtttgatt gtgtccagta tgggcttttc cagcatgatg agtgcaggag tcatgggcaa
    17941 gctaggtgac aaggtgggca atcatcgtct cttggttgtc gcccagtttt attcagtcat
    18001 catctatctc ctctgtgcca atgcctctag cccccttcaa ctaggactct atcgtttcct
    18061 ctttggattg ggaaccggtg ccttgattcc cggggttaat gccctactca gcaaaatgac
    18121 tcccaaagcc ggcatttcga gggtctttgc cttcaatcag gtattctttt atctgggagg
    18181 tgttgttggt cccatggcag gttctgcagt agcaggtcaa tttggctacc atgctgtctt
    18241 ttatgcgacg agcctttgtg ttgcctttag ttgtctcttt aacctgattc aatttcgaac
    18301 attattaaaa gtaaaggaaa tctagtgcga gtaaaaatta atctcaaatg ctcctcttgt
    18361 gacagtatca attacctaac cagtaaaaat tcaaaaaccc atccagacaa gattgaggtt
    18421 ttaaagtatt gtcccaagga aagaaaagta accctacatc ttgaatctaa gtagatttta
    18481 tggtaaaata atagggattt taaggagttt gatatgtata acctattatt aaccatttta
    18541 ttagtattat ctgttgtgat tgtgattgca attttcatgc aaccaaccaa aaaccaatcc
    18601 agcaatgtat ttgatgccag ttcaggtgat ttgtttgaac gcagtaaagc tcgcggtttt
    18661 gaagctgtaa tgcagcgttt gacagggatt ttagtctttt tctggctagc cattgcctta
    18721 gcattgacgg tattatcaag tagataagaa aataatgggc aggactaggt ctttgcctct
    18781 ttttattttt aaaggatgtt tgagaaggtt ttacagtaaa agaaaattaa aaaatctaga
    18841 aagaaaatat gaaagataga ataaaagaat atttacaaga caagggaaag atgactgtta
    18901 atgatttggc tcaggctttg ggaaaagaca gttccaagga ttttcgtgag ttgattaaaa
    18961 ccttgtcctt aatggaaaga aagcaccaaa ttcgttttga agaagatggt agtctgacat
    19021 tagaaattaa gaaaaaacat gagattaccc tcaaggggat ttttcatgcc cataaaaatg
    19081 gctttggctt tgttagtctg gaaggcgagg aggacgacct ttttgtaggg aaaaatgatg
    19141 tcaactatgc tattgatggt gataccgtcg aggtagtgat taagaaagtc gctgaccgca
    19201 ataagggaac agcagcagaa gccaaaatta ttgatatcct agaacacagt ttgacaacag
    19261 ttgtcgggca aatcgttctg gatcaggaaa agcctaagta tgctggctat attcgttcaa
    19321 aaaatcagaa aatcagtcaa ccgatttatg ttaagaaacc agccctaaag ttagaaggaa
    19381 cagaagttct caaggtcttt atcgataaat acccaagcaa gaaacatgat ttctttgtcg
    19441 cgagtgttct cgatgtagtg ggacactcaa cggatgtcgg aattgatgtt cttgaggtct
    19501 tggaatcaat ggacattgta tccgagtttc cagaagctgt tgttaaggaa gcagaaagtg
    19561 tgcctgatgc tccgtctcaa aaggatatgg aaggtcgtct ggatctaaga gatgaaatta
    19621 cctttaccat tgacggtgcg gatgccaagg acttggacga tgcagtgcat atcaaggctc
    19681 tgaaaaatgg caatctggag cttggggttc acatcgcaga tgtttcttat tatgtgaccg
    19741 aggggtctgc ccttgacaag gaagccctta accgtgcgac ttctgtttac gtgacagacc
    19801 gagtggtgcc aatgcttcca gaacgactat caaatggcat ctgctctctc aatccccaag
    19861 ttgaccgcct gacccagtct gctattatgg agattgataa acatggtcgt gtggtcaact
    19921 ataccattac acaaacagtt atcaagacca gttttcgtat gacctatagc gatgtcaatg
    19981 atatcctagc tggcgatgaa gaaaagagaa aagaatatca taaaattgta ttaagtatcg
    20041 aactcatggc caagcttcat gaaactttag aaaacatgcg tgtgaaacgt ggagctctca
    20101 attttgatac caatgaagcg aagattttag tggataaaca aggtaagcct gttgatatcg
    20161 ttcttcggca gcgtggtatt gccgagcgga tgattgagtc ttttatgttg atggctaatg
    20221 aaacagttgc cgaacatttc agcaagttgg atttgccttt tatctatcga attcacgagg
    20281 agcctaaggc tgaaaaggtt cagaagttta ttgattatgc ttcgagtttt ggcttgcgca
    20341 tttatggaac tgccagtgag attagtcagg aggcacttca agacatcatg cgtgctgttg
    20401 agggagaacc ttatgcagat gtattgtcca tgatgcttct tcgctctatg cagcaggctc
    20461 gttattcgga gcacaatcac ggccactatg gactagctgc tgactattat actcacttta
    20521 ccagtccaat tcgtcgttat ccagaccttc ttgttcaccg tatgattcga gattacggct
    20581 gttctaagga aatagcagag cattttgaac aagtgattcc agagattgcg acccagtctt
    20641 ccaaccgtga acgtcgtgcc atagaagctg agcgtgaagt cgaagccatg aaaaaggctg
    20701 agtatatgga agaatacgtg ggtgaagagt atgatgcagt tgtatcaagt attgtcaaat
    20761 tcggtctctt tgtcgaattg ccaaacacag ttgaaggctt gattcacatc actaatctac
    20821 ctgaatttta tcatttcaat gagcgtgatt tgactcttcg tggagaaaaa tcaggtatca
    20881 ctttccgagt gggtcagcag atccgtatcc gtgttgaaag agcggataaa atgactggag
    20941 agattgattt ttcattcgta cctagtgagt ttgatgtgat tgaaaaaggc ttgaaacagt
    21001 ctagtcgtag tggcagaggt cgtggttcaa atcgtcgttc ggataagaag gaagacaaga
    21061 gaaaattagg acgctcaaat gataagcgta agcattcaca aaaagacaag aagaaaaaag
    21121 gaaagaaacc tttttacaag gaagtagcta agaaaggagc caagcatggc aaagggcgag
    21181 ggaaaggtcg tcgcacaaaa taaaaaggca cgccacgact atacaatcgt agatacgcta
    21241 gaggcaggga tggtcctgac tggaactgaa atcaagagtg tacgagctgc tcgaattaat
    21301 ctcaaggatg gctttgctca agtgaaaaat ggagaagttt ggctgagcaa tgttcatatc
    21361 gcgccttacg aagagggcaa tatctggaac caggaaccag aacgtcgtcg taaactcctg
    21421 cttcataaaa agcaaattca aaaattggaa caagagacca aagggacagg aatgacctta
    21481 gttcccctta aggtctatat aaaagatggc tacgctaagc ttcttttagg acttgccaaa
    21541 gggaagcatg actatgacaa acgggagtct atcaaacgtc gtgagcaaaa tcgagatatc
    21601 gcgcgtgtga tgaaagctgt taatcagcga taaaaagagg aattgaaaat ggaaaaatca
    21661 gttgcctata aacgcatgcc tttgtggaat aaacaaacaa tgcctgaagc tgttcagcaa
    21721 aagcacaata caaaagttgg gacttggggg aaaattactg tcttgaaggg agctctcaag
    21781 tttattgaat tgacagaaga aggggaagtt ctagctgaac acctctttga agcaggggca
    21841 gacaatccaa tggcccaacc tcaagcctgg caccgagtgg aagctgccac agatgatgtg
    21901 gaatggtact tggaatttta ttgtaaacct gaggattatt ttgctaaaaa atacaatacc
    21961 aatcctgttc attcagaggt cctagaggcc atgcagacag tgaaacaagg gaaagctttg
    22021 gatttgggtt gtggtcaggg gcgtaattct ctttttctag cccagcaaga ttttgatgtg
    22081 acggctgtag atcaaaatgg actagctctt gaaatcttgc aaagcattgt ggagcaggaa
    22141 gatttggaca tgcctgttgg cctttacgat atcaattcag ctagcattga acaagaatat
    22201 gattttatcg tttcaacagt tgttctcatg tttctacaag cggaccgcat tccagctatt
    22261 attcaaaata tgcaggagaa aaccagtgtt ggtggttaca accttatcgt ttgtgccatg
    22321 gacacggagg attatccttg ctcggttaac ttcccattca cctttaaaga aggagaactg
    22381 gcagactatt acaaggattg ggaattggtt aagtacaatg aaaatccagg ccatttgcac
    22441 cgtcgcgatg agaatggcaa tcgtattcaa ctacgctttg cgaccttact agctaagaaa
    22501 atcaagtaaa cacacatgaa gattagg
//
LOCUS       DBEJZV010000030        21709 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.30, whole genome shotgun sequence.
ACCESSION   DBEJZV010000030 DBEJZV010000000
VERSION     DBEJZV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21709
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.30"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..1348
                     /gene="dcm"
                     /locus_tag="ACL3S0_001587"
                     /pseudo
     CDS             1..1348
                     /gene="dcm"
                     /locus_tag="ACL3S0_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            1332..1781
                     /locus_tag="ACL3S0_001588"
                     /pseudo
     CDS             1332..1781
                     /locus_tag="ACL3S0_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1774..2154
                     /locus_tag="ACL3S0_001589"
     CDS             1774..2154
                     /locus_tag="ACL3S0_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR1312473.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIGLPFVVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            2167..2400
                     /locus_tag="ACL3S0_001590"
     CDS             2167..2400
                     /locus_tag="ACL3S0_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGR1312474.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQILDLDYEDLFRR"
     gene            2403..2990
                     /locus_tag="ACL3S0_001591"
     CDS             2403..2990
                     /locus_tag="ACL3S0_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR1312475.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYGASLFS
                     FLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLCFSLIHAQGSTNQTNLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
     gene            3388..4197
                     /locus_tag="ACL3S0_001592"
     CDS             3388..4197
                     /locus_tag="ACL3S0_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGR1312476.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            4202..4903
                     /locus_tag="ACL3S0_001593"
     CDS             4202..4903
                     /locus_tag="ACL3S0_001593"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR1312477.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            4928..5845
                     /locus_tag="ACL3S0_001594"
     CDS             4928..5845
                     /locus_tag="ACL3S0_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HGR1312478.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            5873..7414
                     /locus_tag="ACL3S0_001595"
     CDS             5873..7414
                     /locus_tag="ACL3S0_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HGR1312479.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            7433..7891
                     /locus_tag="ACL3S0_001596"
     CDS             7433..7891
                     /locus_tag="ACL3S0_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR1312480.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            7893..10115
                     /locus_tag="ACL3S0_001597"
     CDS             7893..10115
                     /locus_tag="ACL3S0_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004308 - exo-alpha-sialidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sialidase domain-containing protein"
                     /protein_id="HGR1312481.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            10155..11264
                     /locus_tag="ACL3S0_001598"
     CDS             10155..11264
                     /locus_tag="ACL3S0_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR1312482.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            11421..12311
                     /locus_tag="ACL3S0_001599"
     CDS             11421..12311
                     /locus_tag="ACL3S0_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR1312483.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            12336..12659
                     /locus_tag="ACL3S0_001600"
     CDS             12336..12659
                     /locus_tag="ACL3S0_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312484.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            12649..14640
                     /locus_tag="ACL3S0_001601"
     CDS             12649..14640
                     /locus_tag="ACL3S0_001601"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HGR1312485.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            14656..15132
                     /locus_tag="ACL3S0_001602"
     CDS             14656..15132
                     /locus_tag="ACL3S0_001602"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HGR1312486.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            15166..15747
                     /locus_tag="ACL3S0_001603"
     CDS             15166..15747
                     /locus_tag="ACL3S0_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312487.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            15812..16819
                     /locus_tag="ACL3S0_001604"
     CDS             15812..16819
                     /locus_tag="ACL3S0_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HGR1312488.1"
                     /translation="MDTNLFSKINTTISVKENDFITEEKFQKIIQSKDTETLAFILES
                     TPYHLSIDILEDPSQTEISLMTKLVNDYRWAYAESPSDIIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVREVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVEMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKTLDQGRYNVEGPLVLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYG
                     S"
     gene            16809..17129
                     /locus_tag="ACL3S0_001605"
     CDS             16809..17129
                     /locus_tag="ACL3S0_001605"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HGR1312489.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            17192..18967
                     /locus_tag="ACL3S0_001606"
     CDS             17192..18967
                     /locus_tag="ACL3S0_001606"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HGR1312490.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            18968..20353
                     /locus_tag="ACL3S0_001607"
     CDS             18968..20353
                     /locus_tag="ACL3S0_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HGR1312491.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            20376..20987
                     /locus_tag="ACL3S0_001608"
     CDS             20376..20987
                     /locus_tag="ACL3S0_001608"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HGR1312492.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            21260..21445
                     /locus_tag="ACL3S0_001609"
     CDS             21260..21445
                     /locus_tag="ACL3S0_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312493.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            21426..>21709
                     /gene="tnpB"
                     /locus_tag="ACL3S0_001610"
     CDS             21426..>21709
                     /gene="tnpB"
                     /locus_tag="ACL3S0_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR1312494.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQV"
BASE COUNT         7311 a         3118 c         4343 g         6937 t
ORIGIN      
        1 agatttattt gctgggatag gaggctttag gatgggaatg gaagctcaag ggcatgagtg
       61 cttgggattt tgtgagattg ataaatttgc taggaaatct tataagtcca tttttcaaac
      121 ggaaggagaa atagaatttc atgacatacg agatgtttca gatgacgaat ttaaaaaact
      181 tagagggaaa gtcgatgtca tctgtggggg attcccttgt caagcatttt caatcgcagg
      241 aagacgattg ggatttgaag atactagagg aactttgttc tttgaaattg ctcgggcggc
      301 caaacaaatc caaccacgtt ttctttttct tgaaaatgtt aaaggcctac tcaatcacga
      361 taagggacgg acgttcacca caatacttac cacacttgat gagttggggt ttgatgttga
      421 gtggcaggtg cttaacagta aggattttgg cgttcccaaa aacagagaga gggtgtttat
      481 tatcggacat tctagaaaga aaggtaccag actcttattt cctttcagac gagaaggtca
      541 agcaactaac tctgagactt tgaaagcact aggaaatttg aatccatcaa gaagtggaat
      601 gagcggtaaa gtctattatt cagaaggtct tgcgccaacc ttagttcgtg gtaaaggaga
      661 aggatttaaa gttgcgattc cttgtatgac accagataga ttagacaaga gacaaaatgg
      721 gagacgcttt aaggaaaatc aagagccgat gtttacttta aatactcagg atcgttatgg
      781 cattgtcgtt gttggagatt taccgactag ctttaaggag acaggtcgtg tctatggaag
      841 tgagggctta tctccaacac tgactacgat gcaaggagga gataaaatcc ccaaaatact
      901 aattccagaa ccaatccaat ttctaaaagt acgggaagca acgaaaaaag gatatgctca
      961 agcagagatt ggggattcaa tcaatttaga aagaccaagt tctcagtatc gtcgtggtag
     1021 agttggaaaa ggtatagcta atacgttaac aactagtggt caaatgggag tagtagtggc
     1081 tagctatgaa ggagaagata aacaagttta ccaagtagct ggtgttttaa tagatggaca
     1141 attttaccgt ttgagaatac gacgaatcac tcctaaagag tgttttcgat tgcatggctt
     1201 tcctgattag gcttttgaag ctgctagaaa agtctctatt aatagtcagc tctataaaca
     1261 agttggtaat agtgtaaccg ttcctgtgat tgccgcaatc gcaaagaaat taaaagaaat
     1321 agaggaaaaa gataaaagca ttaaataaag aatcaatact agattgtgat gaattagaaa
     1381 cagaattaca tgatgcagaa atcaaacagc tggatgaaca aatatttttg atgcccaatt
     1441 atccatgtga gtttgaggta acatttttag atgattacca taaaaaacat aattacccac
     1501 tattttatga atcctatctt caaaacgtta tggaattcct tgaaagtcag gatataaaga
     1561 acggagttaa tgcctttgta gatgataatc agaatcttgt ttttgtttta tattgacaag
     1621 actatcgagc cgagggaaaa gaggggatac ttacaaccca agtaactgta aaagcttatg
     1681 atgaagacaa gaaatcgatt aacttctcaa agttgttaga ttccttaatc gtctcagaat
     1741 atcaaatgga agcaaatttg ttggaggtct cccatgattg atctctatct aagtaaaaat
     1801 agccaaagaa atcaacttct tttagacttc ttccaaaact atggcattga ggtatcttgt
     1861 cattcagttt ctgaaatgac aaaggacaaa ttaattgaga tgatgagcta ttcttcagat
     1921 tgttttgagt ttttatctcc caatttatta cgatttaaga accgtgacaa tctaagatta
     1981 acggatttcg ttgagataat tttaaaaaat cctgaactaa ccatcggact tccttttgtg
     2041 gtttcaaata agcgggttta tccaagtctg aatttggaag aggctagagc tctattgcca
     2101 agagatacga aacaattgat ttacatggca caaacacatt atttatctaa ctaaaggaga
     2161 agtaatatgg ctgaacgatt ttgggagaac ttgtccatta ttttggctga aagaaatatc
     2221 agctggattg agttaaccag aaaaatgttt gcgggagagt ttcactatcc aagtgaattg
     2281 aatcgtttat atcaaaagat tcgccactac aagatggaac aacgaatgcc tcaaagtcca
     2341 tgggtagaaa ggattgtgca gatattagat ttagattatg aagatttatt tcggaggtaa
     2401 ctatgaaaag aataattcca gtttatatat tccaacaagt aaatgtccta ttggtatctc
     2461 tatacttatt gaaatttctt tgtatcggtg agttaactat actacaggtt ctctatggtg
     2521 cgtctctttt ttctttttta tggatgtatg gtcaacgaaa acaagtggtc aaggtcaata
     2581 tgaaaactag gatgaaatgc cttggtattg gactagctag tctactgatt ataagtctat
     2641 gttttagcct gattcatgct caaggaagca cgaatcaaac aaatttaatt ggccttcaac
     2701 atcaagttcc ttggttttca tttttattgt tcttaatcaa tgcgagtatg gttgaagaat
     2761 ttctgtatcg tgaaatttta tggaacttgg ttagaaaatt agatattcga gttgctttga
     2821 caagtgtttt atttgcctta gtacatcatc caggaaccat tctagcttgg tgtctgtacg
     2881 tttcacttgg aatgttttta ggtatggtgc gctataaatc tgacttatgg ggaagtatgg
     2941 ggttacattt ggtgtggaac tttttagttt atagtttgct gcttttttaa aataggtgac
     3001 ctgatttatc tcataaatct gtagttttta tgggattctc ttttaattta gaaataaaat
     3061 atattaccta tataaaataa agaaactaga aatatttttt caattttttt agaaataaaa
     3121 tattatatag aaattccgaa aagaaataat aaaaccaaaa taaaatatta ctaaaatatt
     3181 ttaatatgaa catattatta gtgataaacg ttcttacaat acatataatt acgataaaaa
     3241 gaataaaaac tattatattt ttatgtttgt tgttctgtta tgaaacgaaa gaaattggaa
     3301 actagtttct aatttatgaa aaatattgaa aaaaaaaaaa gtgttaaaat aaagaatgta
     3361 aacgtttact tcaactaagg agctcatatg ttactgcaaa aagaactaat tccaatgata
     3421 gaagctaact taccaaatat ggcatatgct gaaaaagaca ttgctaaatt cttcttaaaa
     3481 cagcaacctc tgaatgatta ttcatctaaa gcattgtgcg aataccttaa tgtatccaaa
     3541 gcaacattga ctcgatttgc gaaaaaatgt ggttttaaag gttttagaca attcattttc
     3601 aaataccaag agatgattca tgagaaagaa aagttggcat tatatacaga ggcaacagaa
     3661 aaagttttat ccgactatga ggaaatgttg agaaaaactt acacggttct tgatgaagtt
     3721 caacttgagc gtattgctga gatgatagaa actgctgagc gtgtatatct ctacggtaaa
     3781 ggaagttctg ttcttgcttt acaagaaatg aagatgagat ttatgcgtct cggagtgatt
     3841 ggtgaagtat tatcagacga ggatatgatt ttgtggagta gcttactact taatgaaaat
     3901 tgccttgtca ttggagcatc catttcaggt caaactgata ttgtactaga aggtctacaa
     3961 aaagctgcag ataaaggcgc taaaacagtt ttaatgacta caagaaaatt tgacgaagaa
     4021 gattgtttct ttgatgaact attgttatta gcttcgaccg atcatctctc gtatggcaat
     4081 cgcatatcac ctcagtttcc aatactttta attacagact gcttattctc taattatctg
     4141 gaaagtccag agagacaata ttattacaat caaactatta tccataagga ggaataataa
     4201 aatgagccaa atttggacta aagaaaaatt tataagccaa gttcaaggtg gagtcattgt
     4261 ttcttgtcaa gctttacctg gtgaagccct ttataatgaa gaatttagct tgatgccttt
     4321 tatggctaaa gcagctttag aggcaggagc agtgggcatt cgcgcaaatt ctgtgcgtga
     4381 tattaaagca attcagaaag tagtagattt accaataatt ggaattatca aaagggatta
     4441 tccacctcaa gaaccatata ttactgctac gatgaaagaa gtagatgaac ttgtagaatg
     4501 cggaacaaca gtcattgcat ttgatgcaac tttaagacca agatatgatg gcttagttgt
     4561 cagtgaattt atcaaaaaaa taaaagaaaa atatccgaat caattgctga tggcggatgt
     4621 aagtaattta gatgaaggtc tctatgcatt taaatcaggc gttgattttg ttggtacaac
     4681 attatcaggt tacacaagta caagtgtaca atcagatgag cctgattttg aactaatgaa
     4741 aaaattggct gattttaata ttccggtaat tgccgaagga aaaattcatt atccagaaca
     4801 attaaaaaaa gcttatagtt taggtgttac cagtgtagtc attggtggag cgattacacg
     4861 tccaaaagaa attgctcagc gatttattaa tgtcatcaaa taaaaaacaa tataaaggag
     4921 aaatctgatg aaagatttaa ctaaatacaa aggcgttatc cctgcatttt atgcttgcta
     4981 tgatgaaaat ggtgaaatta gccaagatcg tgtaaaatct ctggtacaat atttcattga
     5041 caaaggtgta aaaggtatct atgtaaatgg ttcttcaggt gaatgtattt accaaagtgt
     5101 agaagatcgt aaacaaatta ttgaagctgt tatggaagtt gctaaaggta aattaacagt
     5161 tatcaaccat attgcatgta ataacacgaa agatagtatc gaattggcaa aacattcaga
     5221 aagtgttgga gtcgatgcta ttgcagctat cccacctatt tatttcaaat tgccagagta
     5281 ttcaatcgca gcatattgga atgcaatgag tgaagctgcg tcaaatacag attttattat
     5341 ctataatatt ccacaattgg caggggttgc gttgactggt agtttgtatg caacaatgcg
     5401 tcaaaatcct cgtgtgattg gagttaaaaa ttcttctatg cctgtacaag atattcaaat
     5461 gtttgtagct gcaggtggag aagattacat tgtattcaat ggtccagatg aacaatatct
     5521 tggtggtcgc ttgatgggag cagaagctgg tattggtggt acttatggcg ttatgccaga
     5581 tttgttcttg aaattggaaa gtttgattca agaacgagat ttagatacag ctaaaaaact
     5641 tcaatatgct atcaatgaag ttatctataa gatgatatca ggtaaggcaa atatgtatgc
     5701 tgtagcaaaa gaagttttgc gtctaaatga aaaacttgat ttaggttctg ttcgtcaacc
     5761 tttagaagca ttggcagaag gtgacttgga agttgcaaaa caagcagcag aacttattca
     5821 acaagcacga aaagaatttt tataataaat aaaatcaata tggagatatg ttatgggcac
     5881 aacaggattt acaataattg acttaattat cttgattgtt tatttacttg cggtgttggt
     5941 tgcaggtatc tatttctcta aaaaagagat gaaaggaaaa gagttcttta aaggagatgg
     6001 ttcggttcct tggtatgtta cttcggtatc catttttgcc acaatgctca gtccgatttc
     6061 cttcttggga ctcgctggta gctcttatgc aggtagctgg attttatggt ttgctcaatt
     6121 agggatggta gtagctattc cactgacaat tcgttttatc ttacctatct ttgcacggat
     6181 agacatcgat acggcatatg attacttgga taaacgtttt aattctaaag cacttcgtat
     6241 tatttcagca ctcttgttta ttatttatca attgggacgt atgtctatca ttatgtacct
     6301 cccatcagct ggtttatcag tattgacagg aattgacatc aatattttga ttattttgat
     6361 gggtgtagtt gcaattgttt attcttatac tggtggtcta aaatccgtat tatggacaga
     6421 ctttattcaa ggtgtgattc tgattagtgg tgtcgtttta gctttatttg tactgattgc
     6481 taatattaaa ggtggctttg gtgcagtagc agaaacatta gcaaacggga aattccttgc
     6541 tgcaaatgaa aaacttttcg atcctaactt gctttcaaac tccatctttt taattgtgat
     6601 gggttcaggc tttacaatct tgtcttccta tgcttcatct caagatttgg ttcaacgttt
     6661 tactacaaca caaaatatta agaaacttaa taagatgttg ttcacaaacg gtgttttgtc
     6721 acttgcaact gcaacagtct tttacttgat tggtacaggc ttgtacgtat tctatcaagt
     6781 acaaaatgca gatagtgcag ctagcaatat ccctcaagac caaatcttta tgtactttat
     6841 tgcataccag ttaccagtag gtatcacagg tttgatcttg gcagcgattt atgcagcatc
     6901 tcaatcaact atttcaacag gtttgaactc tgttgcaact tcatggacat tggatattca
     6961 agatgtcatt tctaaaaata tgtcagacaa tcgtcgtacg aaaattgcac aattcgtatc
     7021 tctagcagta ggtttattct caattggtgt ttccattgtc atggctcact cagatattaa
     7081 atctgcatac gaatggttca atagtttcat gggacttgta cttggtctac ttggtggtgt
     7141 atttattctt ggatttgttt ctaaaaaagc aaataaacaa ggtgcttatg cagcgctgat
     7201 tgtatcaacc atcgtcatgg tatttattaa atacttcctt cctccaacag ctgttagcta
     7261 ctgggcatat tcattgattt caatctctgt atcagtagtt tcaggttata ttgtatctgt
     7321 tcttactgga aataaagtat ctgcacctaa atatacaacg attcatgata ttacagaaat
     7381 taaagcggat tcaagttggg aagttcgtca ctaatagaaa agagaaaata atatgattat
     7441 ttctgaacaa tctgatttta aacgatatgc ttctgtcaat aaatattttt caaaagtctg
     7501 tgatttttta gaaaatacaa atttgacaga tttagttgat ggaaaaattg atattgacgg
     7561 ggaaaatgtt tttgcaaatt gtatgactta tctagctgat ggagttccag gagatatttt
     7621 tgaaactcat aagaaatatt tagatattca tattgttgtt gaaaatactg aaaaaatggc
     7681 agtaacttcc ccagttcgtg cccagtcacg tgtacctttt agcgaagaga aggatattgc
     7741 tttttacgat agcaaagact atcaaattgt tgaattgctt ccagggaata tgttggtgac
     7801 ttttgaagaa gatcttcacc aaccaaagat tcattgcaat gatgaaactg ttaaaaaact
     7861 tgttatcaaa gttttaaacg aggaaaaata aaatgaaaaa aaatattaaa caatatgtaa
     7921 ccttaggtac tgtagtggta ttatcagcat ttgttgctaa ctcagttgca gctcaggaga
     7981 ctgaaacttc tgaagtatca acaccaaagt tggtgcaacc tgttgcacca acgactccga
     8041 tttcggaagt acaacctaca tcggataact cttcggaagt tactgtacaa cctcgaacag
     8101 ttgaaactac tgttaaggat ccatcttcta cagcggaaga aactcctgtc ttagaaaaaa
     8161 ataatgttac tttaacaggg ggcggagaaa atgttactaa agagttaaag gataaattta
     8221 ctagcggtga ctttactgta gtgattaagt acaatcagtc aagtgagaaa ggcttacaag
     8281 ctctgtttgg aatatctaat tccaaacccg gtcaacaaaa tagttatgta gatgtgttcc
     8341 ttagagacaa tggtgagttg gggatggaag cgcgtgatac ttcttccaat aaaaataacc
     8401 tagtatccag acctgcttca gtttggggta agtacaaaca agaggctgtg actaacactg
     8461 ttgcagtagt agcagattca gtcaaaaaaa catattcttt atacgcaaat ggtacaaaag
     8521 tagtagaaaa gaaagtggat aatttcctaa acatcaagga tattaaaggt attgattact
     8581 atatgcttgg gggagtgaaa cgtgcaggaa aaacggcgtt tggttttaac ggaacactag
     8641 aaaatatcaa attctttaat agtgcattgg atgaagaaac tgttaaaaag atgacaacaa
     8701 acgctgttac tggacattta atttatacgg ctaatgatac aacaggttct aactatttcc
     8761 gtattccagt tctgtatact tttagcaatg gtcgggtatt ttcaagcatt gacgctcgtt
     8821 acggtggaac tcatgatttc ttgaataaaa ttaatattgc tacaagttat agtgatgata
     8881 atggtaagac atggactaaa ccaaaattaa cattggcatt cgatgatttt gcgccagtac
     8941 cattagaatg gcctcgtgaa gttggtggac gtgacttaca aatcagcggt ggtgcaacct
     9001 atattgactc tgttattgtt gaaaaaaaga acaaacaagt actcatgttt gctgatgtga
     9061 tgcctgctgg agtaagtttt agagaagcaa ctagaaaaga ttcaggttat aaacaaattg
     9121 atggtaatta ttaccttaaa ttaaggaaac aaggtgatac tgattacaat tatactattc
     9181 gtgagaatgg tactgtatac gacgatcgta ccaacagacc aactgaattt tcagtagata
     9241 aaaatttcgg tattaaacaa aatggtaatt atttgacggt agagcaatat tcggtttcat
     9301 ttgaaaataa taaaaagact gaatatcgta atgggactaa agtccatatg aatatcttct
     9361 acaaagatgc attgtttaaa gtagtgccaa cgaactatat tgcatatatt tctagcaatg
     9421 atcatggcga atcttggtct gcaccaactt tattacctcc tataatggga cttaatcgga
     9481 atgcgccata tttaggtcct ggacgtggaa tcattgaaag ctcaactgga cgtattctta
     9541 ttccgtctta cactggtaaa gagtctgcgt tcatttatag tgacgataat ggagcatctt
     9601 ggaaagttaa agtagtgcca cttccttcta gttggtcagc agaagcacaa tttgtagaat
     9661 tgagtccagg agtaattcaa gcatatatgc gtacaaataa tggtaaaatt gcatatttaa
     9721 caagtaaaga cgcaggtact acttggagtg caccggaata tttgaaattt gtttcaaatc
     9781 caagttatgg aacacaatta tcaatcatca attatagcca attgattgat ggtaaaaagg
     9841 ctgtcatttt aagtactcca aactccacaa atggtcgtaa acacggacaa atttggattg
     9901 gtctaattaa tgatgataat acaattgatt ggcgttatca tcacgacgtt gattatagta
     9961 actatggata ctcatattca acattgacag agttaccaaa tcatgaaatt ggattgatgt
    10021 ttgaaaaatt tgattcatgg tctcgtaatg aacttcatat gaaaaatgtt gtaccatata
    10081 taacatttaa gattgaagat ctgaaaaaga attaaagctg aaatttgaaa atatataaaa
    10141 agaggataaa aattatggta aattacggta ttgttggagc tggatatttt ggagctgatt
    10201 tagctcgctc aatgaacaaa attgaagatg caaaagtggt tgcggtattt gacccaaatc
    10261 atggagaaga agttgctcaa gagttgggat cagatgtttg tgcaagttta gatgaacttg
    10321 tagcacgtga agatattgat tgtgtgatcg tagcttcacc tagctacctt caccgtgaac
    10381 cagttgtgaa agctgctcaa catggcaaac acgtattttg tgaaaagcca attgcattgt
    10441 cttatgaaga ttgtaaagcc atggttgacg catgtaaaga aaataatgtc atctttatgg
    10501 ctggtcacat catgaacttc tttaacggtg tacaccatgc taaagaattg attactcaag
    10561 gtaaaatcgg taaagttctt tattgccatg ctgctcgtac aggttgggaa gaacaacaac
    10621 caactgtatc atggaagaaa cttcgttctc aatctggagg acatttgtac caccatattc
    10681 atgaattaga ttgcattcag tttatcatgg gaggacttcc tgaaaaagcg acaatggtag
    10741 gaggcaatgt atatcataaa ggtgaaaact ttggtgatga agatgatatg ctcattgtaa
    10801 acttagaata ctctgatgat cgttatgctg ttttggaata tggtaatgct ttccgttggg
    10861 gtgaacacta cgtcttgatt caaggaactg aaggagctat caaacttgac ttgttcaata
    10921 ctggcggtac tcttcgtgtt aaaggtgaag gagaatcaca cttcttagtt catgaaactc
    10981 aagaggaaga tgatgatcgt acagctatct ataccggtcg tggtatggat ggagcaattg
    11041 cgtacggtaa accaggagta cgttgcccat tatggttgca aacatgtatt gataaagaaa
    11101 tggaatatct acatgacatc attaaaggtg gagaaattac agaagaattt gaaaaacttc
    11161 tcaatggtgt agctgcttta gaatcaatcg ctaccgctga tgcatgtact ttatcagtta
    11221 aagaagatcg aaaagtaagt ctttcagaaa tcacaaatgc ttaacttttg taaaacagaa
    11281 tagtaaattc ttgtcattat ataatttcta aagttctgtg atacaactca ttgaataaag
    11341 aaatagagat gggactggga taatgcccag tcccattttt tatcaaaaag taatgagatc
    11401 aaaaatgtgg gagtgttgaa atgaagatta taggtatcga tattggcgga acaacaatta
    11461 aggcagattt atacgatgag tttggaacga gtttgaatca tttcaaagag atagaaacaa
    11521 ttattgacta tgatttggga acgaatcaga tattaaatca ggtctgtgat ttaattggtg
    11581 agtatacttt aaatcattca attgatggtg ttgggatttc cactgctgga gttgttaatg
    11641 ctaatactgg agaaatcatc tatgcaggct atacaatacc agggtatatc ggagtaaact
    11701 ttactgccga aatagaaaaa cgttttgggt tgtatacttt tgttgaaaat gatgttaatt
    11761 gtgctgcatt aggtgaattg tggaagggac aagccaaaga taagaaaaat gtagtaatgg
    11821 ttactattgg aacaggtata ggaggcagta ttattgtcaa cggacaaatt gttaacggat
    11881 ttaactatac tgctggtgaa gtaggttata ttcctgtagg taattcggat tggcaaagta
    11941 aagcctcaac aaccgcattg attcatttat atcaaaaaaa gagcttgaaa actaatcaaa
    12001 ctggacgtac tttcttcact gatttaagat ctggagataa agttgctgaa gaaacttttg
    12061 aaatttttgt agaaaatcta acaaaaggtt tattaacgat ttcttatcta cttaatccag
    12121 aaattctcat attaggaggt gggattctgg atagtaagga tattttgtta cctgaaattc
    12181 aaagttcttt agctaaaaat gcaatggata ataggttttt acctaaaaat cttgtggcag
    12241 ctacattagg aaatgaagct ggtcgtatag gagctgtaaa aaatttctta gatagaattt
    12301 ctaataaata gtatgtaaga taaggaggtg tcacaatgac taactctgta ttttcgacaa
    12361 tgcaagatat tgagaatgtt gcaaccgata ttataaaatc atatgataat gagatttata
    12421 cttataaagc tgtttcccaa gaagaattgg aaaaactaga aaaaagttat gatgaaaaaa
    12481 gtcacgaaga attagtttca atagaaagca atttagaaat gaaacaacag aaccttattg
    12541 atgaggttaa taaaacaatc aaggaaaatg atgcaaatat tcagtatatt tcatcaagta
    12601 ggagaggaga atttgtagaa aaaattattg gtagggtggt agaaaaatat ggccattagt
    12661 cagatgaaaa gaatctctct actattttct aaaagtagtc ttgatgatgt tttaaaaact
    12721 attcaagaac tagagtcagt gcagttccgt gatttaaagg ttcaggataa ctggtcagaa
    12781 gctctagaaa aagatgaagt tgtatttcca actattcaaa tttttcatac ttctaattcc
    12841 aatcatgggg ttattgaggg aaatgatgcc ttgacttatt tgatgaatca acaacaacat
    12901 ttagaagcaa ctgtagagaa attacaagaa tacctaccga aagaaaacac gtttaaatta
    12961 ttgcagcaac ctccgataac tacctcttat gaagaattag agaaatttgg taaagctaat
    13021 gttgctgagg gtgttcttaa aaaagtgaat catcaaatta acagagttca tgaattagaa
    13081 agacacattc aaagtaataa tgaggaaata gagcgattaa taaagtggga aaaattagaa
    13141 attgttcctg cgaatttaga acaattttct ttctgtaaag gaaaagtcgg aacaattcca
    13201 aggactgaag ataatcgctt atacaatagt cttttagaaa acaatattga agttcaagaa
    13261 atattttcta atgatagaga gtacggtgtt gttgttttct atcagtctag ttactctata
    13321 gattttgatg aatacttatt tgaaccattt gattattcta gaaaggaatt accgaagcag
    13381 cgagtagtag atttagatca agaaaacatg cagttaataa ctgaaaaaga gaatattatc
    13441 gcatcgttgc aagattcaaa gaaatatttg atagatttac aatggcaaat agactatatt
    13501 ttatctatct atgctcgtca aatctctaag aataactttt tgtgcactcc gcatctagtt
    13561 gcattagaag gatggataga agaaactcgt attttatatt ttataaaagt tatggatgag
    13621 cattttggac attctattta tatttatgaa tcggaaacat tgacggataa tcaagatgaa
    13681 atacctatca aattaacgaa tcattcttta attgaaccat ttgaattatt gacagaaatg
    13741 tatgctctgc ccaaatatta tgagaaagat cctacacctg tattagcacc attttacttt
    13801 acattttttg gaatgatggt tgctgattta ggctatggtt tactattgtt tttaggaaca
    13861 atgttagcat taaaaatttt tcatctacct tcagcaacta agagattttt aaaattcttt
    13921 aatatattag gggtagccgt tgcaatttgg ggtggaatct atggctcatt ttttggatat
    13981 gagttgccat ttcatctgat atctacaacc tctgatgtca tgactatatt agtagtgtca
    14041 gttgtgtttg ggtttattac agtatttgca ggtttgttag cttcaggact acaaaaagta
    14101 agaatgaaga aatatgcaga agcatataat tcaggatttg cgtggtgtgt tattctgctt
    14161 ggcttgttat ttattgctgt tggaatgttg atgcctgata tgagaccgtt atttgtatta
    14221 gggaaatggg tatctatttt taatgctgtg gggattttga ttgtttctat tattcaaacc
    14281 aaaagcttgt caggtattgg agcaggattg tttaatctat ataacatttc atcttatata
    14341 ggtgatttag ttagtttcac tcgattgatg gcattaggat tatctggagc aagtatagca
    14401 tcagctttca atttaattgt tggtttgttt ccgggaatat tggctaaact gacaattgga
    14461 ttagtattat tcattctttt acatgcgatc aatatttttc tatcgttact atcaggatat
    14521 gttcatggag cacgtctgat atttgttgaa ttttttggta agttttatga gggtggagga
    14581 aaaccatttc aacctttgaa ggcttctgag aaatatatta aggttattac aaagaattaa
    14641 tggaggatat atataatgga acatttagca acttattttt caacctatgg aggagctttc
    14701 ttcgctgcat tgggaattgt attggcggtt ggattaagcg gtatggggtc tgcttatgga
    14761 gttggtaagg ctgggcaatc tgccgcagct ttactgaaag aacagcctga aaagtttgcc
    14821 tcagctttga tattgcaatt attgcccgga acacaaggat tatatggttt tgttattgga
    14881 attttaattt ggttgcaatt aactccagaa cttcctttag aaaaaggcgt tgcttatttc
    14941 tttgtagctc ttccaattgc tattgtagga tacttttcag ctaagcatca aggaaatgta
    15001 gcagtagcgg gaatgcaaat cttggctaaa agaccaaaag aattcatgaa gggagcaatt
    15061 ttagctgcca tggtagaaac ctatgcaatt cttgcttttg tcgtatcatt cattttgacc
    15121 cttcgtgtat aagaaataaa tttgcaattc aaaggaggtg tctaaatgag caatttagaa
    15181 aacttacgag agtctgttat tgaacaagct catgaaaaag ggcgtatgaa attattggat
    15241 tccaaaaaga agattgatga tgaatttgaa atgcaaaagt cgctcattat aaagaaaaaa
    15301 gaagctgaac atgaacgaaa gttaaaagaa ttgcaacaga aatatcaaat aatttttcaa
    15361 caattaaaaa ataaggaacg ccaatcaacg ttagtatcaa aacagaaaat attaaaagaa
    15421 ctttttcaat ctgctttact agaaatggaa tcttggagtg cagataaaga aatggagttc
    15481 atctatcgaa ttctggaacg atattcacaa caagaggtca tagtaacctt tggggaacgg
    15541 actttagcta aattcaattt ggaacaatta gagaaattga aattctcttt tccaaattat
    15601 ttatttagtg aacaacctat ctcaaatgaa tcaggcttac ttatttcaat aggtaaaatt
    15661 gatgataact atttgtataa aacattaatt ggatcgattt ctaaggaaga aagttcaagt
    15721 atcgcaaatc aaatttttat caattaagga tgaaattggt taatccttct tagaaatttg
    15781 gagtattcca ataaaattag aaaggtattt tatggatact aatctttttt caaaaataaa
    15841 tacgacgatt tcggtaaaag aaaacgattt tattacagaa gaaaaatttc aaaaaattat
    15901 acaatccaaa gatacggaga cattggcatt tatcttagaa tcaactccct atcatttatc
    15961 gattgacatc ttagaagatc ctagtcagac agagatttcg ctaatgacaa aattagtcaa
    16021 tgattataga tgggcctatg ctgaaagtcc gtctgatata attgtgactt tatttgcttt
    16081 acgatatgtt tatcataata tcaaagtttt attaaaatct aaggcggcaa ttaagaaaga
    16141 tttttctaaa ttattaattc caatagggat ttttgatata gaaagtttaa aacatttagt
    16201 ttcttcctta cattcagata cacttcctga ttttatggtt cgtgaagtag aatcaatttg
    16261 gaatgagtat gaaactttta ataatattcg tgtacttgat gtcggagctg atctagcata
    16321 ttttaaacat ctgaaacttt tatctaatga gttagatgag gtactgtctc aggttattgt
    16381 cgaaatgatt gacttttata atattattac tgtaaaacgt ggtttatctc aaaataagag
    16441 tcatggggat attttacaat tactttcaga tgaaggaagt atttctgcta aagaatttat
    16501 atacattgta gaaaatcaag aaatatttgt gtggttcaat aaaataaatc caagcttaga
    16561 ttcaatcttt tcaacttatg aattgaagat gcaggacgca acaatttcat cttctgagtt
    16621 agaattttta tgtgatttac tattgtataa aactttagat caaggaaggt acaatgtaga
    16681 ggggccgtta gttcttgcta gatatttatt gggatgtgag tttgaagtaa agaatctcag
    16741 aatgatcata tcagctcttc aaaatacaat tccctttgaa tcaataaaag aaaggatacg
    16801 cccacattat ggaagctaat aagtataaaa ttggcataat tggtagccgt gatattattt
    16861 taccatttag catgattggg tttgatatat ttcctgccta ccaagaacaa gaagctataa
    16921 atacactaag aaaattagct caatctgatt atggtgtcat ttatatcact gaagacattg
    16981 cttcaatgat attagataca attcgccatt atgattccca agttgtgcct gctattattt
    17041 tattaccgac tcataaacaa ggtttaaatt taggattaaa acgtatagag gataatgtag
    17101 agaaagcagt aggacacaat attttataat aatgtacaaa attgtctgta atattattct
    17161 ataatttttg gacttagtaa ggagaataac tttgactcaa gggaagatta taaaagtatc
    17221 gggacctcta gttattgcat caggtatgca ggaggctaat attcaagata tttgccgtgt
    17281 aggtaagcta gggttaatcg gtgaaattat tgaaatgaga agagatcagg catctatcca
    17341 agtctatgaa gaaacatctg gtcttggtcc gggagaacct gttgttacaa ctggagaacc
    17401 tctctcggtt gaattagggc caggattgat ttctcaaatg tttgatggca tacaacgccc
    17461 attagatcga tttaaattgg ctactcataa tgattttcta gttcgtgggg tagaagttcc
    17521 aagtttggat agagatatta agtggcattt tgattccact atagcaattg gtcaaaaagt
    17581 gagtacgggt gatattcttg gaactgtcaa ggaaaccgag gtagttaatc ataaaattat
    17641 ggttccttat ggagtatctg gagaagtcgt ttctattgca tctggcgatt ttacaattga
    17701 tgaagttgta tatgaaataa aaaaattgga cggtagtttc tataaaggaa cgcttatgca
    17761 aaaatggcct gtccgcaagg cgcgtcctgt ttctaaacgt ttaattccag aagaaccatt
    17821 aatcacaggt caacgagtta ttgatgcatt ctttccagta accaaagggg gagctgcagc
    17881 agttcctgga ccgtttggag caggaaagac agttgtacaa caccaagtag ctaaatttgc
    17941 caatgttgat attgttattt atgtcggttg tggagaacgt ggaaatgaaa tgacggatgt
    18001 actgaatgag tttcctgagt tgattgaccc taataccgga caatcaatta tgcaacggac
    18061 agttctgatt gctaatactt caaatatgcc tgttgctgct cgtgaggctt caatttatac
    18121 aggaattacc atggctgagt attttcgtga tatgggctac tctgtcgcca ttatggctga
    18181 ttcaacttca cgttgggcag aagcgctacg tgaaatgtca ggacgtctag aagaaatgcc
    18241 tggtgatgag ggttatcctg cttatctggg aagtcgtatc gctgaatatt atgaaagagc
    18301 aggacgttct caggttctag ggcttccaga acgtgaagga acgattactg ctattggagc
    18361 tgtatcgcca cctggtggag atatttcaga accagttact caaaacactt tacggattgt
    18421 gaaagttttt tgggggcttg atgctccgtt ggcacagcga cgtcattttc ctgcaattaa
    18481 ctggcttaca tcttattcac tatataaaga cagtgtgggc acttatatag atggtaaaga
    18541 gaagacagat tggaatagta aaataactcg tgcgatgaac tacttacaac gggaatctag
    18601 tttagaggaa attgttcgtc ttgttggaat tgattctctg tctgataatg aacgactaac
    18661 gatggaaatt gctaaacaaa ttcgagaaga ttatttgcaa cagaacgctt ttgattcggt
    18721 agatacattc acttcgtttg caaaacaaga agcaatgcta agtaatattc tcacttttgc
    18781 tgatcaggca aatcatgctt tagagttggg ttcttacttt acagagatta tggaaggtac
    18841 cgtggcagtt cgagaccgta tggcgagaag taaatatgtt tcagaagata gattagatga
    18901 aatcaaaatt atatcaaatg agattacaca tcaaattcat ttgatattag aaacaggagg
    18961 tctataaatg agtgttataa aagaatacag aactgctagt gaagttgttg ggcctcttat
    19021 gattgttgaa caagtaaata atgtgtctta caatgagtta gttgaaattc aacttcataa
    19081 tggagaaatt cgtcgtggac aagttttaga gatccacgaa gataaagcaa tggttcagct
    19141 ttttgaagga tctagtggaa taaatttaga aaagtctaaa attcgttttg ctggtcatgc
    19201 attagaattg gctgtatctg aggatatggt tggtcgtatt tttaatggga tgggaaaacc
    19261 aattgatggt ggaccagatt taattccaga gaaatattta gatattgatg gtcaagctat
    19321 taatcctgta tctagagatt atccagatga atttattcag acagggatct cctctattga
    19381 tcatttgaat actcttgtac gtggtcaaaa attaccagta ttttcaggtt cgggcttacc
    19441 tcataatgaa ttagctgctc agatagcaag acaagcgact gttttaaatt ctgatgaaaa
    19501 ttttgcggtt gtatttgcag caatgggtat tacttttgaa gaagctgagt tttttatgga
    19561 agaactcaga aaaacaggag cgatcgatcg ttcggtttta tttatgaact tggcaaatga
    19621 tcctgcaatt gagcgtattg caactccccg cattgcttta actgcggcag agtatctagc
    19681 ttttgaaaaa gatatgcacg ttctagttat catgacggat atgactaact attgtgaagc
    19741 gttacgtgaa gtctcggcag ctcgccgtga agttccaggg agacgaggct atccgggata
    19801 tttatataca aatttatcaa ctctatacga aagggctggt cgcttagttg gtaaaaaagg
    19861 ttcggtgaca cagattccta ttttaacaat gccagaagat gacataacac atccaattcc
    19921 tgatttaact ggatacatta ctgaagggca aattattttg tcgcatgagt tgtataatca
    19981 aggttatcgt ccaccaatca atgttttacc ttctctctct cgattaaaag ataagggatc
    20041 tggagaaggt aaaactcgtg gagatcatgc tccaactatg aatcaactgt ttgcagccta
    20101 tgcccaaggg aaaaaggttg aagagttagc agtagtatta ggagaatcgg ctttatctga
    20161 tgtagataaa ttgtatgtga ggtttacaaa gcgttttgaa gaagagtaca taaaccaagg
    20221 attttataaa aatcgaaata tagaagatac gttgaatctt gggtgggaat tactatcaat
    20281 tcttcctaga acagagttaa aacgtatcaa agatgatttg cttgataaat acttaccttt
    20341 ggtagaagtt taatccggaa atggagtgat tatctatggt acgtttgaat gtaaaaccaa
    20401 ctcgtatgga attgaataac ttaaaggaac gtttgacaac agctgaacgt ggacataagt
    20461 tattaaagga taaaagagat gaattgatga ggcgatttat ttctttgatt cgtgagaata
    20521 atcaacttcg gaaagaagtg gaaagttatc taattgataa tctaaaatcc tttgcagttg
    20581 ctaaatcatt aaagaattct caaatggtgg aggaattatt ttcaattcca tcgaaagaaa
    20641 ttgaattatt tgttgagaaa gaaaatatca tgagtgtaac agttcctaga atgcatatga
    20701 atattacttc tcaaaatgag aacagtgaat acagctattt atcttctaat agtgaaatgg
    20761 atgatgtatt tgctacaatg aatagtttaa tttataaatt actaagactg gcagaagttg
    20821 aaaaaacgtg tcagttaatg gctgatgaaa tagaaaaaac acgtagacgt gtaaatggtt
    20881 tagaatactc gattattcca aacttgtcgg aaactattca ttatatagaa ttgaaactag
    20941 aggaggcaga aagagccaat ttagttcgta ttatgaaagt gaagtagatc ctttatttag
    21001 attattaatt agatgaacaa atatcagctt ggataaggct ttaagccttt ctaagctttt
    21061 tttattgaca gtatcaggat atctttttca aaattttggt ttgttagata atgaaaatgt
    21121 ttctactaat ctagatttag gattagtaaa tcgtaaatgt aattatatag aaagtaagcg
    21181 cgtcataaca aggtatctat cattcatgga gctcctcctg tatactatta gtaaagtaaa
    21241 actattggag gatattttaa tgccacaacc tattgttcct gtagagattc cacaatctcg
    21301 tcgttttgat tctaaaaaga gaaatgatat tctgcttaaa attcgtattg gcaagcttga
    21361 agtaagtttt tttcaatctc tcaatctcga aatggtagaa cagcttttgg ataaggtgtt
    21421 gctctatgac aattcatcta tctagcctag gggaggtcta tctcgtgtgt gggaaaactg
    21481 atatgagaca aggaatcgat tcactggctt atctggttaa aacccacttt gaattggatc
    21541 ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt aaagtccttt
    21601 actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc agattgattt
    21661 ggctaagtac agaaaaggat gtcaaagctc tcacaccaga acaagtaga
//
LOCUS       DBEJZV010000031        21581 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.31, whole genome shotgun sequence.
ACCESSION   DBEJZV010000031 DBEJZV010000000
VERSION     DBEJZV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21581
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.31"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..333
                     /locus_tag="ACL3S0_001611"
                     /pseudo
     CDS             1..333
                     /locus_tag="ACL3S0_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(408..1328)
                     /gene="cysK"
                     /locus_tag="ACL3S0_001612"
     CDS             complement(408..1328)
                     /gene="cysK"
                     /locus_tag="ACL3S0_001612"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGR1312495.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1613..2248)
                     /locus_tag="ACL3S0_001613"
     CDS             complement(1613..2248)
                     /locus_tag="ACL3S0_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGR1312496.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQIDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            2304..3602
                     /locus_tag="ACL3S0_001614"
     CDS             2304..3602
                     /locus_tag="ACL3S0_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR1312497.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     SIILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKATKEIQMMNKEAGL"
     gene            3599..4261
                     /locus_tag="ACL3S0_001615"
     CDS             3599..4261
                     /locus_tag="ACL3S0_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGR1312498.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4341..4889
                     /gene="raiA"
                     /locus_tag="ACL3S0_001616"
     CDS             4341..4889
                     /gene="raiA"
                     /locus_tag="ACL3S0_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGR1312499.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5025..6998
                     /locus_tag="ACL3S0_001617"
     CDS             5025..6998
                     /locus_tag="ACL3S0_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGR1312500.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDETSESDISQINSFVANFISEFSEKHMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            6995..7447
                     /gene="rplI"
                     /locus_tag="ACL3S0_001618"
     CDS             6995..7447
                     /gene="rplI"
                     /locus_tag="ACL3S0_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGR1312501.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7491..8843
                     /gene="dnaB"
                     /locus_tag="ACL3S0_001619"
     CDS             7491..8843
                     /gene="dnaB"
                     /locus_tag="ACL3S0_001619"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGR1312502.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            8845..9111
                     /locus_tag="ACL3S0_001620"
     CDS             8845..9111
                     /locus_tag="ACL3S0_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGR1312503.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9200..10546
                     /gene="cbpD"
                     /locus_tag="ACL3S0_001621"
     CDS             9200..10546
                     /gene="cbpD"
                     /locus_tag="ACL3S0_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGR1312504.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10629..10731
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10802..11092
                     /locus_tag="ACL3S0_001622"
     CDS             10802..11092
                     /locus_tag="ACL3S0_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGR1312505.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11055..11813
                     /locus_tag="ACL3S0_001623"
     CDS             11055..11813
                     /locus_tag="ACL3S0_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312506.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            11851..12858
                     /locus_tag="ACL3S0_001624"
     CDS             11851..12858
                     /locus_tag="ACL3S0_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1312507.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            12858..13586
                     /locus_tag="ACL3S0_001625"
     CDS             12858..13586
                     /locus_tag="ACL3S0_001625"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312508.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13705..14163
                     /locus_tag="ACL3S0_001626"
     CDS             13705..14163
                     /locus_tag="ACL3S0_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGR1312509.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            14165..16597
                     /locus_tag="ACL3S0_001627"
     CDS             14165..16597
                     /locus_tag="ACL3S0_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGR1312510.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLISKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLTE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            17239..17892
                     /gene="rr06"
                     /locus_tag="ACL3S0_001628"
     CDS             17239..17892
                     /gene="rr06"
                     /locus_tag="ACL3S0_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGR1312511.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17889..19220
                     /gene="hk06"
                     /locus_tag="ACL3S0_001629"
     CDS             17889..19220
                     /gene="hk06"
                     /locus_tag="ACL3S0_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGR1312512.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVSNILESYQMDYSFLPYEHGMEFKISL"
     gene            19315..19842
                     /locus_tag="ACL3S0_001630"
     CDS             19315..19842
                     /locus_tag="ACL3S0_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGR1312513.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19921..>21581
                     /gene="pspC"
                     /locus_tag="ACL3S0_001631"
     CDS             19921..>21581
                     /gene="pspC"
                     /locus_tag="ACL3S0_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HGR1312514.1"
                     /translation="MFASKSERKVHYSIRKFSVGVASVAVASLVMGSVVHATENERTT
                     QVPTSSNRGKPERRKAAEQFDEYINKMIQLDKRKHTQNLAFNIQLSRIKTEYLNGLKE
                     KSEAELPSKIKAELDAAFKQFKKDTLPTEPEKKVAEAEKKVEEAEKKVAEAKKKAKAQ
                     KEEDHRNYPTITYKTLDLEIAEFDVKVKEAELELVKKEADESRNEGTINQAKAKVESE
                     KAEATRLKKIKTDREKAEEEEAKRRADAKEQDESKRRKSRGKRGALGEQATPDKKEND
                     AKSSDSSVGEETLPSPSLKPGKKVAEAEKKVEEADKKAKAQKEEDRRNYPTNTYKTLE
                     LEIAESDVKVKEAELELVKEEAKESRNEEKIKQAKAKVESKKAEATRLEKIKTDRKKA
                     EEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAEEPENPVPAPKPENPAEQPKAEKP
                     ADQQAEEDYARRSEEEYNRLTQQQPPKPEQPAPAPKIGWKQENGMWYFYNTDGSMATG
                     WLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNG"
BASE COUNT         6823 a         3573 c         4903 g         6282 t
ORIGIN      
        1 ctatttggag cccctttata acctcttgcg agagagacta ttgactcagc ccttacttca
       61 tgcggatgaa acttcttata gggtgctaga gagtgatagt cagctgactt actattggac
      121 ttttttgtct gggaaagctg agaaacaagg gattacgctt taccatcatg tcctaatcga
      181 tttgttcata tcttatttca atccattata aatagtgaga aatatctatc ctatcttcta
      241 gaatgtcttc caaacgtgga aactctcgta aacaaagagg ttttagaggc ctatttacca
      301 tggattaaag ttgtacaaga aaagtgcaaa taagaaatct ccagattagg aactatccgt
      361 gagttctcta gtctggagat ttttcaatat acttcgttat tggacggtta caattcataa
      421 agtgctgtag agagataacg ttcaccgtta tctggtgcta gggcaaggac ttttttacct
      481 gtacctaatt ttttggcaac ctcgatggct ccgtagatag ctgcagctga ggaaatccct
      541 acaaggaagc cttcttttcc accaatttca cgtccgagtg caagagcgtc atctgatgtt
      601 acacgaacga taccatcata ggctttagta tcaagtgtat caggaataaa tccagctgag
      661 ataccttgaa ttttgtgagg accgggtttt tcaccagata gaatagcaga ttcatctgct
      721 tctactgcaa aaacttgaat gttagaattt tctgatttga gtgcatgaga aacaccagaa
      781 atcgttccac cggtacctac tccagcaaca aaggcatcta atccatcttt accgaaagca
      841 gctagtatct cagctcctgt tgttctttcg tgtacttctg gattagctgg attgtcaaat
      901 tgaagaggaa ggaaaccatc acgttcagca gcgatttctt gagccttagc aatagcacct
      961 ttcattccct cgctaccagg agttaggacg agttcagcac cataagcttg gataatttta
     1021 cgtcgttcta cactcatagt ttcaggcata acgatgacga ctttataccc tttagcagca
     1081 cctacccatg aaagtccaat accagtgttt ccacttgttg cttcaacaat agtagaacca
     1141 ggtttcagaa taccatcttg ttcagctttt tcaatcatgc taagggcaat acggtctttt
     1201 acagatgaac caggattaaa tgcttcaagc tttatataga cgtctgcagc accttctggc
     1261 acgatgttgt taagtttaac aattggtgtt tgaccgatta attcagtaat gttgttataa
     1321 atagacatat gaatacctct ttgtataaga tatctttagt ataacgctat ctataccatt
     1381 tgtaaaatat agaaatccta tcgaagcgat aggatttcta tatatcatag atcaaagtca
     1441 ttaattttca agtgattgcg ttcagctaat tctagtaaat aggtgtgaag gaaaacgata
     1501 tcaggtttcg tttgaattgc ttcattttct agtatatttt ggtacgcatc tttttatttt
     1561 gctcgctaaa gtagttgtga gaatgtcaac gaaacgttgt attattcatt gtttacacta
     1621 agtttacagg aacttcaacc tctcgtaaac cttggtcagt taaagtgact tttccattaa
     1681 aaaactccac aagtgcagct ttaatagttt ctttttcttc tttatcaaca taaatcatcg
     1741 tatcgatttg atctgtaaag tttgtatcca gctccatgag atcatgttct ttaaggaagt
     1801 tactgtactc ttggtactga gcataagaca tttgaatagc aatgccagcc tgttctttta
     1861 tttcaataat accaatttct ttgacagcta aggcgacact gccggcgtaa gcacgaatta
     1921 gtcctccagc gcctagttta ataccaccaa agtagcgtgt cacgaccaca cagacattgg
     1981 tgagattgtg attttctagt accccaagca tgggaacacc agcagtacca ctaggttcac
     2041 catcatcact tgtacgttta atttcactac gttctccaat aataaaggca gagcagttat
     2101 gtgtcgcttt gtagtgttct tttttgatgg cagtaatgaa gtcacgagcc tcttcttcgc
     2161 tataaacacg cttggcatgg cagataaagc gagatttttt gatttcttct tggacttgac
     2221 cgtcctcttt aattgttcta aattccatga tttaattgta ctaaaaaatc atctaaagtg
     2281 ctagttttta cgaataaaga agtatgaaag taaatttaga ttatctcggt cgtttattta
     2341 ctgagaatga attaacagaa gaagaacgtc agttggcgga gaaacttcca gcaatgagaa
     2401 aggagaaggg gaaacttttc tgtcaacgct gtaatagtat tattctagaa gaatggtatt
     2461 tgcccatcgg tgcttactat tgtcgagagt gcttgctgat gaagcgagtc agaagtgatc
     2521 aaactttata ctattttccg caggaggatt ttccgaagca agatgttctc aaatggcgcg
     2581 gccaattaac tccttttcaa gagaaggtgt cagagggact gcttcaagca gtagacaagc
     2641 aaaagccaac cttagttcat gcggtaacag gagctggaaa gacagaaatg atttatcaag
     2701 tagtggctaa agtgatcaat gcgggtggtg cagtgtgttt ggctagtcct cgcatagatg
     2761 tttgtttgga gctgtacaag cgcctgcaac aggatttttc ttgcggaata gctttgctac
     2821 atggagaatc ggaaccttat tttcgaacac cactagttgt tgcaacaacc catcagttat
     2881 tgaagtttta tcaagctttt gatttgctga tagtggatga agtagatgct tttccttatg
     2941 ttgataatcc catgctttac cacgctgtca agaatagtgt aaaggagaat ggattgagaa
     3001 tctttttaac agcgacttcg accaatgagt tagataaaaa ggtccgttta ggagaactaa
     3061 aaagactgaa tttaccgaga cggtttcatg gaaatccgtt gattattcca aaaccaattt
     3121 ggttatcgga ttttaatcgc tacttagaca agaatcgttt gtcaccaaag ttaaagtcct
     3181 atattgagaa gcagagaaag acagcttatc cgttactcat ttttgcttca gaaattaaga
     3241 aaggggagca gttagcagaa atcttacagg agcaatttcc aaatgagaaa attggctttg
     3301 tatcttctgt aacagaggat cgattagagc aagtacaagc ttttcgagat ggagaactga
     3361 caatacttat cagtacgaca atcttggagc gtggagttac cttcccttgt gtggatgttt
     3421 tcgtagtaga ggccaatcat cgtttgttta ccaagtctag tttgattcag attggtggac
     3481 gagttggacg aagcatggat agaccgacag gagatttgct tttcttccat gatgggttaa
     3541 atgcttcaat caagaaggcg actaaggaaa ttcagatgat gaataaggag gctggtctat
     3601 gaagtgcttg ttatgtgggc agactatgaa gactgtttta acttttagta gtctcttact
     3661 tctgaggaat gatgactctt gtctttgttc agactgtgat tctacttttg aaagaattgg
     3721 ggaagagaac tgtccaaatt gtatgaaaac agagttgtca acaaagtgtc aagattgtca
     3781 actttggtgt aaagagggag ttgaagtcag tcatagagcg atttttactt acaatcaagc
     3841 tatgaaggat tttttcagtc ggtataagtt tgatggagac ttcctgttaa gaaaagtttt
     3901 cgcttcattt ttaagtgagg agttgaaaaa gtacaaagag tatcaatttg ttgtaattcc
     3961 cctaagtcct gatagatatg ctaatagagg atttaatcag gttgagggct tggtagaggc
     4021 agcaggcttt gagtatctgg atttattaga gaaaagagaa gagagagcca gttcttctaa
     4081 aaatcgttca gagcgcttgg ggacagaact tcctttcttt attaaaagtg gagtcactat
     4141 tcctaaaaaa atcctactta tagatgatat ctatactaca ggagcaacta taaatcgtgt
     4201 taagaaactg ttggaagaag ctggtgctaa ggatgtaaaa acattttccc ttgtaagatg
     4261 aggaaaaaat ttgcaaaaat agaatgaaag cgttataata aaatcataaa aacaaaaatg
     4321 tttagaaaga aggtactcat atgattaaat atagtatccg tggtgaaaac ctagaagtaa
     4381 cagaagcaat tcgtgattat gtagtttcta aactcgaaaa gatcgaaaag tacttccaac
     4441 cagaacaaga gttggatgcc cgaattaact taaaagttta tcgtgaaaaa acggctaaag
     4501 tggaagtaac gattccgctt ggatctatta ctctccgcgc agaagatgta tctcaagata
     4561 tgtatggttc aattgacctt gtaactgata aaattgaacg tcagattcgt aaaaataaaa
     4621 caaaaatcga gcgtaaaaat aaaaataagg tagcaactgg tcaattattt acagatgctt
     4681 tggtggaaga ttcaaatgtt gtccagtcta aagttgttcg ttcaaaacaa attgatttaa
     4741 aaccaatgga tttggaagaa gcaattctac aaatggattt attggggcat gatttcttta
     4801 tctatgtgga tgttgaagat cagacaacca atgtgattta tcgtcgtgag gatggcgaaa
     4861 ttggtttgtt agaggttaaa gaatcttaat ttcaatatgt gtaaaggtag gtttactgaa
     4921 ttgtaaacta cctttttctt ataattgata gaattactga ttacactttt aaaaagtcgc
     4981 tttttgaggg gtattatggt ataatgggtg ccaagaggtt ttgaatgaaa aaattttatg
     5041 taagtccaat ttttcctatt ctagtaggat tgattgcgtt tggagtctta tccactttca
     5101 ttatttttgt taataataat ctgttgacgg ttttaatttt gtttcttttt gtaggaggct
     5161 atgttttttt atttaagaaa ctgagagtgc attatacaag gagtgatgta gaacagatac
     5221 agtatgtaaa ccaccaagcg gaagaaagtt tgacagctct attggaacag atgcctgtag
     5281 gtgttatgaa attgaatttg tcttctggag aggttgagtg gtttaatccc tatgctgaat
     5341 tgattttgac caaggaagat ggtgattttg atttagaagc tgttcaaacg attatcaagg
     5401 cttcagtagg aaatccgtct acttatgcca agcttggtga gaagcgttat gctgttcata
     5461 tggatgcttc ttccggtgtt ttgtattttg tagatgtatc cagggaacaa gccataacag
     5521 atgaattggt aacaagtaga ccagtgattg ggattgtctc tgtggataat tatgatgatt
     5581 tggaggatga aacttctgag tcagatatta gtcaaatcaa tagttttgta gctaatttta
     5641 tatcagagtt ttcagaaaaa cacatgatgt tttctcgtcg ggtaagtatg gatcgatttt
     5701 atctatttac tgactacacg gtgcttgagg gcttgatgaa tgataaattt tctgttattg
     5761 atgctttcag agaagagtcg aaacagagac agttgccctt gaccttaagt atgggatttt
     5821 cttatggcga tggaaatcat gatgagatag ggaaagttgc tttgctcaat ttgaacttgg
     5881 ctgaagtacg tggtggcgac caggtggttg ttaaggaaaa cgacgaaacg aaaaatccag
     5941 tttattttgg tggtgggtct gctgcttcaa tcaagcgtac acggactcgt acgcgcgcta
     6001 tgatgacagc tatttcagat aagattcgga gtgtagatca ggtttttgta gtcggtcaca
     6061 aaaatttaga catggatgct ttgggctctg ctgtaggtat gcagttgttc gccagcaatg
     6121 tgattgaaaa tagctatgct ctttatgatg aagaacaaat gtctccagat attgaacgag
     6181 ctgtttcatt catagaaaaa gaaggagtta cgaagttgtt gtctgttaag gatgcaatgg
     6241 ggatggtgac caatcgttct ttgttgattc ttgtagacca ttcaaagaca gccttaacat
     6301 tatcaaaaga attttatgat ttatttaccc aaaccattgt tattgaccac catagaaggg
     6361 atcaggattt tccagataat gcggttatta cttatatcga aagtggtgca agtagtgcca
     6421 gtgagttggt aacggaattg attcagttcc agaattctaa gaaaaatcgt ttgagtcgta
     6481 tgcaagcaag tgttttgatg gctggtatga tgttggatac taaaaatttc acctcgcgag
     6541 taactagtcg gacatttgat gttgctagct atctcagaac gcgcggaagt gatagtattg
     6601 ctatccagga aatcgctgcg acagattttg aagaatatcg tgaggtcaat gaacttattt
     6661 tacaggggcg taaattaggt tcagatgtac taatagcaga ggctaaggac acgaaatgct
     6721 atgatacagt tgttattagt aaggcagcag atgccatgtt agccatgtca ggtattgaag
     6781 cgagttttgt tcttgcgaag aatacacaag gatttatctc tatctcagct cgaagtcgta
     6841 gtaaactgaa tgtacaacgg attatggaag agttaggcgg tggaggccac tttaatttgg
     6901 cagcagctca aattaaagat gtaaccttgt cagaagcagg tgaaaaactg acagaaattg
     6961 tattaaatga aataaaggaa aaggagaaag aagaatgaaa gtaatctttt tagcagatgt
     7021 taaaggaaaa ggtaaaaaag gcgaaattaa ggaagtacca acagggtatg cgcaaaactt
     7081 tcttatcaaa aagaatctag ccaaagaagc gactgctcaa gctgtaggtg aacttcgagg
     7141 taaacaaaaa tcggaagaaa aagctcacgc tgagatgatt gcagaaggaa aagcaattaa
     7201 agcacaactt gaagcagaag aaactgttgt agaatttgtt gaaaaagttg gtccagatgg
     7261 tcgtaccttt ggttctatta ccaataagaa gattgcagaa gaattgcaaa agcaatttgg
     7321 aattaagatt gataaacgtc atattcaagt acaagctccg attcgagcgg ttggtttgat
     7381 tgatgtgcca gtgaaaatct atcaagatat cacaagtgta atcaatcttc gtgtgaaaga
     7441 aggataagtt tacactttct tgacaagatt gtaaaaggaa gggaagtctg atggcagaag
     7501 tagaagagtt acgagtacaa cctcaagata tcttagctga gcaatccgtt ttaggggcta
     7561 tctttattga tgagagtaaa cttgtttttg tgcgagaata cattgagtct cgggactttt
     7621 ttaagtatgc ccatcgtttg attttccaag ccatggtcga tttatccgat cgtggtgatg
     7681 ccatagatgc aacaacggtt cgtactatcc ttgataatca aggtgattta cagaatattg
     7741 gtggcttgtc ttacttggtt gagattgtta attctgtgcc aacttctgct aatgcggagt
     7801 attatgctaa gattgttgca gaaaaagcaa tgctacgtcg tttaattgcc aagttgacag
     7861 agtctgtcaa ccaagcttac gaagcgtcac aaccagctga tgaaattatt gctcaggcag
     7921 aaaaagggct gattgatgtc agtgaaaatg caaatcgaag cgggtttaag aacattcgag
     7981 atgtgttgaa tctcaacttt ggaaatctgg aagctcgctc gcaacaaacg accgatatta
     8041 caggtattgc gacaggttat cgtgatttgg atcatatgac aacaggactt catgaggagg
     8101 agttgattat cttagcagct cgtccagcag ttggtaagac agcatttgcc ttgaatatcg
     8161 ctcagaacat tgggactaag ttggacaaaa cggttgctat tttttcactc gaaatgggtg
     8221 cggaaagctt ggtagatcgt atgttagctg cagaaggctt agtggagtca cattctatcc
     8281 gtacagggca attgacagat gaggagtggc aaaaatatac tattgctcag ggtaatctag
     8341 ctaacgccag tatctatatc gatgatacgc caggtattcg gattacagag attcgttctc
     8401 gttctcgtaa attggctcaa gaaactggaa atcttggttt gattttgata gactatttgc
     8461 aacttatcac gggaactggt cgagaaaatc gtcaacaaga agtttctgaa atttctcgtc
     8521 agttgaaaat actagccaag gaattgaagg ttccagtaat cgctctgagt cagctttctc
     8581 gtggtgtaga acaacgtcag gacaagagac cggtcttgtc tgatattcgt gaatctgggt
     8641 ctattgagca ggacgctgat atcgtagctt ttctctatcg cgatgactac tatgaacgtg
     8701 gtggtgaaga agaggagggt atcccaaata ataaggtgga agttattatc gagaaaaacc
     8761 gtagtggagc tcgtggaaca gtggaattga ttttccaaaa agaatacaat aaattttcaa
     8821 gtatctcaaa gagggaggca taagatgtca gatgcattta cagatgtagc caagatgaaa
     8881 aaaatcaaag aagaaatcaa ggcacatgag ggacaagtcg tagaaatgac tttggagaat
     8941 ggtcgtaagc gccaaaaaaa tagattgggt aagctaattg aagtttatcc atctctattt
     9001 attgtggagt ttggggatgt ggaaggagat aaacaagtta atgtttacgt tgaatccttt
     9061 acttactcag atattcttac agaaaagaat ttgattcatt atcttgacta aagtgagaaa
     9121 ttttctcact ttttcttttt tctccgaata atttaggtga aggcaatcat cgctttatat
     9181 tatttttcaa ggaggaagaa tgaaaatttt accgtttata gcaagaggaa caagttatta
     9241 cttgaagatg tcagttaaaa agcttgttcc ttttttagta gtaggattga tgctagcagc
     9301 tggtgatagt gtctatgcct attccagagg aaatggatcg attgcgcgtg gggatgatta
     9361 tcctgcttat tataaaaatg ggagccagga gattgatcag tggcgcatgt attctcgtca
     9421 gtgtacttct tttgtagcct ttcgtttgag taatgtcaat ggttttgaaa ttccggcagc
     9481 ttatggaaat gcgaatgaat ggggacatcg tgctcgtcgg gaaggttatc gtgtagataa
     9541 tacaccgacg attggttcca ttacttggtc tactgcagga acttatggtc atgttgcctg
     9601 ggtgtcaaat gtaatgggag atcagattga gattgaggaa tataactatg gttatacaga
     9661 atcctataat aaacgagtta taaaagcaaa cacgatgaca ggatttattc attttaaaga
     9721 tttggatggc ggcagtgttg ggaatagtca atcctcagct tcaacaggcg gaactcatta
     9781 ttttaagacc aagtctgcta ttaaaactga acccctagct agcggaactg tgattgatta
     9841 ctattatcct ggggagaagg ttcattatga tcagatactt gaaaaagacg gctataagtg
     9901 gttgagttat actgcctata atggaagcta tcgttatgtt caattggagg ctgtgaataa
     9961 aaatcctcta ggtaattctg ttctttcttc aacaggtgga actcattatt ttaagaccaa
    10021 gtctgctatc aaaactgaac ccctagttag cggaactgtg attgattact attatcctgg
    10081 ggagaaggtt cattatgatc agatacttga aaaagacggc tacaagtggt tgagttatac
    10141 tgcctataat ggaagtcgtc gctatataca gctagaggga gtgacttctt cacaaaatta
    10201 tcagaatcaa tcaggaaata tctctagcta tggatccaat aatagttcaa ctgtcggttg
    10261 gaagaaaata aatggtagtt ggtatcattt caaatcaaat ggttctaaat caacaggatg
    10321 gctgaaagac ggttctagct ggtattattt gaaattatct ggtgaaatgc agacaggatg
    10381 gttaaaggaa aatggctcgt ggtattatct gggtagttca ggggcaatga aaacaggctg
    10441 gtaccaggtc tctggtaagt ggtattattc ttactcttca ggcgccttag ctgttaatac
    10501 gacggtggat ggctacagag taaacagtga tggagaacga gtatagaaaa ttggagtagg
    10561 agaaatttcc tgctcttttc tgtaagcagt ttccttgaca tttttcttat tttgcgctat
    10621 catatataca tataatatat gggagtctgt gtacagtctg agaggaagtg ttaaacttcg
    10681 accgcacctg atctgggtaa tgccagcgga gggaacgata cttagtctaa ttttgcacct
    10741 tttccatgta tggtaaaggt ttttcttttt ttaaaaagga aaacgagaag aggaggttct
    10801 tatgaaagca agcattgcct tgcaagtttt acccctagta caggggattg atcggatagc
    10861 tgttattgat caggtcattg cttatctgca aactcaagaa gtgacgatgg tagtgacacc
    10921 atttgaaacg gtcttggaag gggagtttga tgagcttatg cgcattctaa aagaagcgct
    10981 ggaagtggca gggcaggagg cagacaatgt ctttgccaat gtcaaaataa atgtaggaga
    11041 gattttaagt attgatgaga aacttgagaa gtatactgag acgacacatt agtctattgg
    11101 gctttctcgg agtattgtca atctggcagt tagcaggttt tcttaaactt ctccccaagt
    11161 ttatcctgcc gacacctctt gaaattctcc agccctttgt tcgtgacaga gaatttctct
    11221 ggcaccatag ctgggcgacc ttgagagtgg ctttactggg gctgattttg ggagttttga
    11281 ttgcctgtct tatggctgta ctcatggata gtttgacttg gctcaatgac ctgatttacc
    11341 ctatgatggt ggtcattcag accattccga ccattgccat agctcctatc ctggtcttgt
    11401 ggctaggtta tgggattttg cccaagattg tcttgattat cttaacgaca acctttccca
    11461 tcatcgtcag cattttggac ggttttaggc attgcgacaa ggatatgctg actttgttta
    11521 gtctgatgcg ggccaagcct tggcaaatcc tgtggcattt taaaatcccg gttagcctgc
    11581 cttactttta tgcaggtctg agggtcagtg tctcctacgc ctttatcaca actgtggtat
    11641 ctgagtggtt gggaggtttt gaaggtcttg gtgtttatat gattcagtct aaaaaactgt
    11701 ttcagtatga taccatgttt gccattatta ttctggtgtc gattatcagt cttttgggta
    11761 tgaagctggt cgatattagt gaaaaatatg ttattaaatg gaaacgtact taaaatagag
    11821 cgtttttgaa aaagaaaaga ggaaatcaaa atgaagaaaa catggaaagt gtttttaacg
    11881 cttgtaacag ctcttgtagc tgttgtgctt gtggcctgtg gtcaaggaac tgcttctaaa
    11941 gacaacaaag aggcagaact taagaaggtt gactttatcc tagactggac accaaatacc
    12001 aaccacacag ggctttatgt tgccaaggaa aaaggttatt tcaaagaagc tggagtggat
    12061 gttgatttga aattgccacc agaagaaagt tcttctgact tggttatcaa cggaaaggca
    12121 ccatttgcag tgtatttcca agactacatg gctaagaaat tggaaaaagg agcaggaatc
    12181 actgccgttg cagctattgt tgaacacaat acatcaggaa tcatctctcg taaatctgat
    12241 aatgtaagca gtccaaaaga cttggttggt aagaaatatg ggacatggaa tgacccaact
    12301 gaacttgcta tgttgaaaac cttggtagaa tctcaaggtg gagactttga gaaggttgaa
    12361 aaagtaccaa ataacgactc aaactcaatc acaccgattg ccaatggcgt ctttgatact
    12421 gcttggattt actacggttg ggatggtatc cttgctaaat ctcaaggtgt agatgctaac
    12481 ttcatgtact tgaaagacta tgtcaaggag tttgactact attcaccagt tatcatcgca
    12541 aacaacgact atctgaaaga taacaaagaa gaagctcgca aagtcatcca agccatcaaa
    12601 aaaggctacc aatatgccat ggaacatcca gaagaagctg cagatattct catcaagaat
    12661 gcacctgaac tcaaggaaaa acgtgacttt gtcatcgaat ctcaaaaata cttgtcaaaa
    12721 gaatacgcaa gcgacaagga aaaatggggt caatttgacg cagctcgctg gaatgctttc
    12781 tacaaatggg ataaagaaaa tggtatcctt aaagaagact tgacagacaa aggcttcacc
    12841 aacgaatttg tgaaataatg acagaaatta gactagagca cgtcagttat gcctatggtc
    12901 aggagaggat tttagaggat atcaacctac aggtgacttc aggcgaagtg gtttccatcc
    12961 taggcccaag tggtgttgga aagaccaccc tctttaatct aatcgctggg attttagaag
    13021 ttcagtcagg gagaattgtc cttgatggtg aagaaaatcc caaggggcgc gtgagttata
    13081 tgttgcaaaa ggatctgctc ttggagcaca agacggtgct tggaaatatc attctgcccc
    13141 tcttgattca aaaggtggat aaggcagaag ctatttcccg agcggataaa attcttgcga
    13201 ccttccagct gacagctgta agagacaagt atcctcatga acttagcggt gggatgcgcc
    13261 agcgtgtagc cttactccgg acctaccttt ttgggcacaa gctctttctc ttagatgagg
    13321 cctttagcgc cttggatgag atgacaaaga tggaactcca cgcttggtat cttgagattc
    13381 acaagcagtt gcagctaaca accctgatca tcacgcatag tattgaggag gccctcaatc
    13441 tcagcgaccg catctatatc ttgaaaaatc gccctgggca gattgtttca gaaattaaac
    13501 tagattggtc tgaagatgag gacaaggaag tccaaaagat tgcctacaaa cgtcaaatct
    13561 tggcagaatt aggcttagat aagtagaaaa atagggagtt ggtgaagatt atcctttacc
    13621 agcgcccttt ttcttttaaa aatgagaaaa tttcggtata atagtcaaac aaggtcaagg
    13681 tttaaagaga gaggtgggtt tgttatgaga tttaaaaata catcggatca tattgaggcc
    13741 tacatcaagg cgattttaga tcaatctggt atcgtggagt tgcaacggag tcagttggca
    13801 gatacctttc aggttgttcc tagtcagatt aactacgtga tcaagacacg ctttacggaa
    13861 agtagaggct acttggttga aagtaagcgt ggtggtggag gctacattcg tataggacga
    13921 attgagtttt ctagtcatca tgaaatgctc cgggagctgc tttactcgat tggtgagcga
    13981 gtcagtcaag aaatttatga ggatattctc cagcttttgg ttgagcagga attgatgacc
    14041 aagcaggaga tgaatttgct agaatcagta gctttggatc gcgttttagg agaagaagct
    14101 ccagttgttc gagcaaacat gctacgtcag atcatacaag aggtagatag aaaagggaag
    14161 taagatgaac tattcaaaag cattgaatga atgtatcgaa agtgcctaca tggttgctgg
    14221 acattttgga gctcgttatc tagagtcttg gcacttgttg attgccatgt ctaatcacag
    14281 ttatagtgta gcaggggcaa ctttaaatga ttatccgtat gagatggacc gtttagaaga
    14341 ggtggctttg gaactgactg aaacggacta tagccaggat gaaaccttta cggaattgcc
    14401 gttctcccgt cgtttgcagg ttctttttga cgaagcagag tatgtagcgt cagtggtcca
    14461 tgctaaggtg ctagggacag agcacgtcct ctatgcgatt ttgcatgatg gcaatgcctt
    14521 ggcgactcgt atcttggaga gggctggttt ttcttatgaa gacaagaaag atcaggtcaa
    14581 gattgctgct cttcgtcgaa atttagaaga acgggcaggc tggactcgtg aagatctcaa
    14641 ggctttacgc caacgccatc gtacagtagc tgacaagcaa aattctatgg ccaatatgat
    14701 gggcatgccg cagactccga gtggtggtct cgaggattat acgcatgatt tgacagagca
    14761 agcgcgttct ggcaagttag aaccagtcat cggtcgggac aaggaaatct cacgtatgat
    14821 tcaaatcttg agccgtaaga ctaagaacaa ccctgtcttg gttggggatg ctggtgtcgg
    14881 gaaaacagct ctggcccttg gtcttgccca gcgtattgct agtggtgacg tgcctgcgga
    14941 aatggctaag atgcgcgtgt tagaacttga tttgatgaat gtcgttgcag ggacacgctt
    15001 ccgtggtgac tttgaagaac gcatgaataa tatcatcaag gatattgaag aagatggcca
    15061 agtcatcctc tttatcgatg aactccacac catcatgggt tctggtagcg ggattgattc
    15121 gactctggat gcggccaata tcttgaaacc agccttggcg cgtggaactt tgagaacggt
    15181 tggtgccacc actcaggaag aatatcaaaa acatatcgaa aaagatgcgg ctctttctcg
    15241 tcgtttcgct aaagtgacga ttgaagaacc aagtgtggca gatagtatga ctattttaca
    15301 aggtttgaag gcgacttatg agaaacatca ccgtgtacaa atcacagatg aagcggttga
    15361 aacagcggtt aagatggctc atcgttattt aaccagtcgt cacttgccag actctgctat
    15421 cgacctcttg gacgaagcag cagcaacagt gcaaaataag gcaaagcatg taaaagcaga
    15481 cgattcagat ttgagtccag ctgacaaggc cctgatggat ggcaagtgga aacaggcagc
    15541 ccagctaatc tcaaaagaag aggaagtacc tgtctacaaa gacttggtga cagagtctga
    15601 tattttgacc accttgagtc gcttgtcagg aatcccagtt caaaagctga ctcagactga
    15661 cgctaagaaa tatctaaatc ttgaagcaga actccataaa cgggttatcg gtcaagatca
    15721 agctgtttca agtattagtc gtgcgattcg ccgtaatcag tcaggaattc gcagtcacaa
    15781 gcgtccgatc ggttccttta tgttcctagg acccacaggt gtcggtaaga ccgagttggc
    15841 caaggctttg gcagaagttc tctttgatga cgaatcagcc cttatccgct ttgatatgag
    15901 tgagtatatg gagaaattcg cagccagccg tctaaatgga gctcctccag gctatgtggg
    15961 ttacgaagaa ggtggggagt tgacagagaa ggttcgcaat aaaccctatt ccgttctcct
    16021 ctttgatgag gtagagaagg ctcacccaga tatctttaat gttctcttgc aggttctgga
    16081 tgacggtgtc ttgacagata gcaagggacg caaggtcgat ttttcaaata ccattatcat
    16141 tatgacatcg aacctaggtg cgactgccct tcgtgatgat aagactgttg gttttggggc
    16201 taaggatatt cgttttgacc aggaaaatat ggaaaaacgc atgtttgaag aactgaaaaa
    16261 agcttataga ccggaattca tcaaccgtat tgatgagaag gtggtcttcc atagcctatc
    16321 tagtgatcat atgcaggaag tggtgaagat tatggtcaag cctttagtgg caagtttgac
    16381 tgaaaaaggc attgacttga aattacaagc ttcagctctg aaattgttag caaatcaagg
    16441 atatgaccca gagatgggag ctcgcccact tcgtagaacc ctgcaaacag aagtggagga
    16501 caagttggca gaacttcttc tcaagggaga tttagtggca ggcagcacac ttaagattgg
    16561 tgtcaaagca ggccagttaa aatttgatat tgcataaaag aataaaagta tcagcatctg
    16621 accataagtc acagtggagt gaaattcaat gaaaatcaaa gagcaaacta ggcagctagc
    16681 cgcaggttgc tcaaaacact ggtttgaggt tgcagataga gctgacgtgg tttgaagaga
    16741 ttttcgaaga gtatgaaact aaaacctata gcttctaaac gatccgtggt tttcatcatt
    16801 caacacaaaa ttcatatgtt tattaccctc cgtcgtattt gtcttagagc gtgtgtagta
    16861 gaaaaagagc agtcttatct gaaattttta ttctttcaaa agagacctgt ttcttttttg
    16921 catgtcaaat ccgttctagc tggtatttga aaaatcaaac taatattcaa tgaaaatcaa
    16981 agaacaaact aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgtagatag
    17041 agctgacgtg gtttgaagag attttcgaag agtataagct gcaagatgaa tgattttctt
    17101 gtattgacgt tgttgttgac aaaaagtagc ggataaatga aatccattcc attatcatag
    17161 atgataggct ggtaggaaat tttcaaatag catacaggaa atagatgtat ggagttctgg
    17221 tagtagaaag ggagagagat gaacatttta gttgcagatg acgaggaaat gattagagaa
    17281 ggaattgcag catttctgac agaagagggt tatcatgtca ttatggctaa ggatggacaa
    17341 gaggtcttgg aaaaatttca agatctccct atccatctca tggtactgga tttaatgatg
    17401 cctaggaaga gtggttttga agtgttaaaa gaaatcaatc aaaagcacga tattcctgtc
    17461 atcgtcttga gtgctctggg agatgaaact actcagtcac aggtatttga tctctatgct
    17521 gatgatcatg tgacaaaacc tttttctttg gtactgcttg tcaagcgtat taaggcgctt
    17581 atcagacgtt actacgtcat agaggatatt tggcgatatc aggatgtaac agtggatttt
    17641 acctcttaca aagcacatta taaaaatgaa gaaattgatc tcaaaccaaa ggaattactg
    17701 gtactaaagt gtttgattca gcataaaaat caagttttaa gtagagagca gatattggaa
    17761 gaaatttcaa aagatgtagc tgatttacct tgtgataggg tcgttgatgt ctatattcgt
    17821 actcttcgca aaaaattagc tttagattgt atcgtgactg tgaaaaatgt tgggtataag
    17881 attagcttat gataaaaaat cctaaattat taaccaagtc ttttttaaga agttttgcaa
    17941 ttctaggtgg tgttggtcta gtcattcata tagctattta tttgaccttt cctttttatt
    18001 atattcaact ggagggggaa aagtttaatg agagcgcaag agtgtttacg gagtatttaa
    18061 agactaagac atctgatgaa attccaagct tactccagtc ttattcaaag tccttgacca
    18121 tatctgctca ccttaaaaga gatattgtag ataagcggct ccctcttgtg catgacttgg
    18181 atattaaaga tggaaagcta tcaaattata tcgtgatgtt agatatgtct gttagtacag
    18241 cagatggtaa acaggtaacc gtgcaatttg ttcacggggt agatgtctac aaagaagcaa
    18301 agaatatttt gcttttgtat ctcccatata catttttggt tacaattgct ttttcctttg
    18361 ttttttctta tttttatact aaacgcttgc tcaatcctct tttttacatt tcagaagtga
    18421 ctagtaaaat gcaagatttg gatgacaata ttcgttttga tgaaagtagg aaagatgaag
    18481 ttggtgaagt tggaaaacag attaatggta tgtatgagca cttgttgaag gttatttatg
    18541 agttggaaag tcgtaatgag caaattgtaa aattgcaaaa tcaaaaggtt tcctttgtcc
    18601 gcggagcatc acatgagttg aaaacccctt tagccagtct tagaattatc ctagagaata
    18661 tgcagcataa tattggagat tacaaagatc atccaaaata tattgcaaag agtataaata
    18721 agattgacca gatgagccac ttattagaag aagtactgga gtcttctaaa ttccaagagt
    18781 ggacagagtg tcgtgagacc ttgactgtta agccagtttt agtagatatt ttatcacgtt
    18841 atcaagaatt agctcattca ataggtgtta caattgaaaa tcaattgaca gatgctacca
    18901 gggtcgtcat gagtcttagg gcattggata aggttttgac aaacctgatt agtaatgcaa
    18961 ttaaatattc agataaaaat gggcgtgtaa tcatatccga gcaagatggc tatctctcta
    19021 tcaaaaatac atgtgcgcct ctaagtgacc aagaactaga acatttattt gatatattct
    19081 atcattctca aatcgtgaca gataaggatg aaagttccgg tttgggtctt tacattgtga
    19141 gtaatatttt agaaagctat caaatggact atagttttct cccttatgaa cacggtatgg
    19201 aatttaagat tagcttgtag acagattagt tttttattaa agttcacata gggttaacat
    19261 aagtgtatta ttctttatat agataaaaat atagataaaa gaaaggatac taatatggta
    19321 ttagcgatta ttttagtaac attccttatt cgattgattt ttttaaagcg ttcgatagag
    19381 aatgagaaac gaatccttag caatggcggg aaagaatttg gagttgagaa tacaaaacga
    19441 ttaacgttgg ctcatattgt tttttatctc tcttgcttgg ttgaggcaat ggtgcacaag
    19501 acaatttttg atggcatggg catggttggt ttggtcttgc ttattttttc tatgctgatg
    19561 ttgatgttgg tgattcactt gttgggagat atttggacag tgaagcttat gcttgtcaat
    19621 aatcacaaat atgtagatca tatcttgttt aggacagtaa aacaccctaa ttacttttta
    19681 aatattttac ctgagttgat tggcttgacc ttgttgagtc atgcctatat gacttttgtt
    19741 ttagtttttc cagtttatgc agttattttg tatcgacgaa tagctgaaga ggaaaagcta
    19801 ttacatgaag ttataatccc aaatggaagc ataaagagat aaatacaaaa ttcgatttat
    19861 atacagttca tattgaagtg atatagtaag gttaaagaaa aaatatagaa ggaaataaac
    19921 atgtttgcat caaaaagcga aagaaaagta cattattcaa ttcgtaaatt tagtgttgga
    19981 gtagctagtg tagctgttgc cagtcttgtt atgggaagtg tggttcatgc gacagagaac
    20041 gagagaacta cccaagtacc cacttcttct aataggggaa agccagaacg taggaaagct
    20101 gctgaacaat tcgatgaata tataaacaaa atgatccaat tagataaaag aaaacatacc
    20161 caaaatttag ccttcaacat acagttgagc agaattaaaa cggagtattt gaatggatta
    20221 aaagagaagt cggaagctga gttgccgtca aaaataaaag cagagttaga cgcagctttt
    20281 aagcagttta aaaaagatac attaccaaca gaaccagaaa aaaaagtagc agaagctgag
    20341 aagaaggttg aagaagctga gaagaaggta gcagaagcta agaaaaaagc caaggctcaa
    20401 aaagaagaag atcaccgtaa ctacccaacc attacttaca aaacgcttga ccttgaaatt
    20461 gctgagttcg atgtgaaagt taaagaagcg gagcttgaac tagtaaaaaa ggaagctgac
    20521 gaatctcgaa acgagggcac aattaaccaa gcaaaagcga aagttgagag tgaaaaagct
    20581 gaggctacaa ggttaaaaaa aatcaagaca gatcgtgaaa aagcagaaga agaagaagct
    20641 aaacgaagag cagatgctaa agagcaagat gaatcaaaga ggcgaaagag tcggggaaaa
    20701 cgaggagctc ttggagagca agcaacacct gataaaaaag aaaatgatgc gaagtcttca
    20761 gattctagcg taggtgaaga aactcttcca agcccatccc tgaaaccagg aaaaaaggta
    20821 gcagaagctg agaagaaggt tgaagaagct gataaaaaag ccaaggctca aaaagaagaa
    20881 gatcgccgta actacccaac caatacttac aaaacgcttg aacttgaaat tgctgagtcc
    20941 gatgtgaaag ttaaagaagc ggagcttgaa ctagtaaaag aggaagctaa ggaatctcga
    21001 aacgaggaaa aaattaagca agcaaaagcg aaagttgaga gtaaaaaagc tgaggctaca
    21061 aggttagaaa aaatcaagac agatcgtaaa aaagcagaag aagaagctaa acgaaaagca
    21121 gcagaagaag ataaagttaa agaaaaacca gctgaacaac cacaaccagc gccggctcct
    21181 caaccagaaa aaccagctga agagcctgag aatccagttc cagctccaaa accagagaat
    21241 ccagctgaac aaccaaaagc agaaaaacca gctgatcaac aagctgaaga agactatgct
    21301 cgtagatcag aagaagaata taatcgcttg actcaacagc aaccgccaaa accagagcaa
    21361 ccagctcctg caccaaaaat aggctggaaa caagaaaacg gtatgtggta cttctacaat
    21421 actgatggtt caatggcgac aggatggctc caaaacaatg gctcatggta ctacctcaac
    21481 agcaatggcg ctatggcgac aggatggctc caaaacaatg gttcatggta ctatctaaac
    21541 gctaatggtt caatggcaac aggatggctc caaaacaatg g
//
LOCUS       DBEJZV010000032        21455 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.32, whole genome shotgun sequence.
ACCESSION   DBEJZV010000032 DBEJZV010000000
VERSION     DBEJZV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.32"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            69..311
                     /gene="relB"
                     /locus_tag="ACL3S0_001632"
     CDS             69..311
                     /gene="relB"
                     /locus_tag="ACL3S0_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGR1312515.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            313..567
                     /locus_tag="ACL3S0_001633"
     CDS             313..567
                     /locus_tag="ACL3S0_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR1312516.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            614..1357
                     /locus_tag="ACL3S0_001634"
                     /pseudo
     CDS             614..1357
                     /locus_tag="ACL3S0_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(1646..2632)
                     /locus_tag="ACL3S0_001635"
     CDS             complement(1646..2632)
                     /locus_tag="ACL3S0_001635"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGR1312517.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2826..5294
                     /gene="gyrA"
                     /locus_tag="ACL3S0_001636"
     CDS             2826..5294
                     /gene="gyrA"
                     /locus_tag="ACL3S0_001636"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGR1312518.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5294..6037
                     /gene="srtA"
                     /locus_tag="ACL3S0_001637"
     CDS             5294..6037
                     /gene="srtA"
                     /locus_tag="ACL3S0_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGR1312519.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWNAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            6281..7078
                     /locus_tag="ACL3S0_001638"
     CDS             6281..7078
                     /locus_tag="ACL3S0_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGR1312520.1"
                     /translation="MISSEFISKIEFACNKKEGLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            7226..8486
                     /locus_tag="ACL3S0_001639"
                     /pseudo
     CDS             7226..8486
                     /locus_tag="ACL3S0_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            8582..9856
                     /locus_tag="ACL3S0_001640"
     CDS             8582..9856
                     /locus_tag="ACL3S0_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGR1312521.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKEHDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            9866..10744
                     /gene="truB"
                     /locus_tag="ACL3S0_001641"
     CDS             9866..10744
                     /gene="truB"
                     /locus_tag="ACL3S0_001641"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGR1312522.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            10985..11287
                     /locus_tag="ACL3S0_001642"
     CDS             10985..11287
                     /locus_tag="ACL3S0_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR1312523.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            11395..12033
                     /gene="udk"
                     /locus_tag="ACL3S0_001643"
     CDS             11395..12033
                     /gene="udk"
                     /locus_tag="ACL3S0_001643"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR1312524.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            12161..13501
                     /gene="xseA"
                     /locus_tag="ACL3S0_001644"
     CDS             12161..13501
                     /gene="xseA"
                     /locus_tag="ACL3S0_001644"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGR1312525.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLIIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            13479..13691
                     /locus_tag="ACL3S0_001645"
     CDS             13479..13691
                     /locus_tag="ACL3S0_001645"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGR1312526.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            13688..14563
                     /locus_tag="ACL3S0_001646"
     CDS             13688..14563
                     /locus_tag="ACL3S0_001646"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGR1312527.1"
                     /translation="MKKQEKLALVESVLEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIASLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIVFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            14556..15371
                     /locus_tag="ACL3S0_001647"
     CDS             14556..15371
                     /locus_tag="ACL3S0_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGR1312528.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            15364..15795
                     /locus_tag="ACL3S0_001648"
     CDS             15364..15795
                     /locus_tag="ACL3S0_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR1312529.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            15802..17469
                     /gene="recN"
                     /locus_tag="ACL3S0_001649"
     CDS             15802..17469
                     /gene="recN"
                     /locus_tag="ACL3S0_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGR1312530.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSEIYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            17471..18199
                     /locus_tag="ACL3S0_001650"
     CDS             17471..18199
                     /locus_tag="ACL3S0_001650"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR1312531.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            18278..20101
                     /gene="lepA"
                     /locus_tag="ACL3S0_001651"
     CDS             18278..20101
                     /gene="lepA"
                     /locus_tag="ACL3S0_001651"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGR1312532.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(20182..20424)
                     /locus_tag="ACL3S0_001652"
     CDS             complement(20182..20424)
                     /locus_tag="ACL3S0_001652"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312533.1"
                     /translation="MKIKEQTRKLAAGYSKHSFEVVDETDEVSSKHGFEVVDETDEVS
                     SKHGFEVVDETDEVSNHTYGKATMTWFEEIFEEYKN"
     gene            20603..21079
                     /locus_tag="ACL3S0_001653"
                     /pseudo
     CDS             20603..21079
                     /locus_tag="ACL3S0_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            21117..21419
                     /locus_tag="ACL3S0_001654"
     CDS             21117..21419
                     /locus_tag="ACL3S0_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1312534.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
BASE COUNT         6526 a         3796 c         4909 g         6224 t
ORIGIN      
        1 tttttatatt gactgaacac ctaaaaagta atacaatggt gttaccatta aaaaagggag
       61 cacaaaagat gactactatt acattaaaag tttctgaagc tgataaaaca tttatgaaag
      121 caatggctaa gtttgaagga gtttcccttt cggaacttat tcgcaccaaa actcttgaag
      181 ccctagaaga tgaatacgat gctcgtgtgg cagatttagc ctatcaagag tatttagaag
      241 acttggaaaa aggagttgaa cccattactt gggaagaaat gatgcatgat ttaggcttga
      301 aggatgaata atttgtataa attagttcca acaagacgtt ttatcaagca attgaaaaaa
      361 ttggaccgtt atacgcagaa gctaattaca aactatttac aaaccaatgt tttggaagac
      421 ccaagacgac acggaaaggc tttggttggt aatcgcgttg gtcaatggcg ctatagaatt
      481 ggtaattatc gagttatcgt acaaattgta gatgatgaat tagtcgttgc tactctagaa
      541 gttggtcatc ggagagatat ttattgaatt aaagctgagt aataacagta tagaaagtaa
      601 ggagagtaaa aatttgaaga aaaaatggtt ttttgcagat tattatgaca caacaattat
      661 tttacttgct ttaatctctg ttattctggt attacttgga tttgctgaga tgactgattt
      721 ggacaatccg ccttatagta ttattgattt agtaatctgg ggtgtttttg taattgatta
      781 tagttggcgc ttttttatta ctaaaagaaa atggcgcttt attcttgaaa atatttttga
      841 tttattgacc attctccctt taaatgctat ttttacagtg tttcgattag gacgtatctt
      901 ccgcttagca aggctgacaa aattactgaa actgactcgt ttacttagaa taattggact
      961 tacaggtaaa ctagaaagaa aaattagtag attcttacga acaaatggat tgatttatat
     1021 cttgtatgtt aatatcttta ttgttctagt agggagttcg attttatccg ttgttgaaga
     1081 aaaatccttc tcagatagtc tttggtgggc tcttgtgaca gtaactactg ttggttatgg
     1141 tgatattgtt ccagtttccc tttttgggaa atggctagca gttttactga tgcttgtcgg
     1201 tattggaaca atagggatgc taacaagtgc tttgacgaac ttttttgtaa aggataatcc
     1261 agatgaacag ataaaacttg ataaactcaa agacgaatta tcgagctaaa gaatattaat
     1321 agagaaacaa tctgaaaaaa tcgaagaact acattgaatg ataaaagact tagttgaaaa
     1381 aatatcataa aggtgagaca aaataaaact tgattcgagg agaaatcaag taagtcttga
     1441 cacaatagaa cgcatattat caggtataaa aacttgatac tatgcgtttt atagagaaat
     1501 aaaataaaat ctgaacaaat caattaggaa tttaaagcat tttataacaa cgttttagag
     1561 tgatggggtg ctatttcaac ttcaacctac tataatacag aaaaaaacaa ctccctgatg
     1621 attcaaggag ttgtctatag ttaaattagt ttttagaagc ttcttggaat tctggatttt
     1681 tccatgcttc gtcaataata gcttgcaatt ctttagcaga tgcttgcatt ttttgagttt
     1741 ctgcatcgtt caatggaatg tttactggac gaacgatacc atgtgcacca acaacagctg
     1801 gttgaccgat aaagacattc tcaactccgt attgaccttc ttggaatact gaaagtggaa
     1861 gtactgcgtt ttcatcgtca aggattgctt tagtgatacg agcaagggct actgcgatac
     1921 cgtagtatgt tgcacctttt ttgttgatga ttgtgtaggc tgcatcacga acaccttcga
     1981 acaattcaat caattcagct tcttgaacat tttgagtgtc tttaaggaat tcttcaaggt
     2041 ttacaccagc gatgttagcg tgtgaccaaa cagcgaactc agagtcaccg tgttcaccca
     2101 tgatgtaggc gtgcactgaa cgagcatcca catccaattt ttcagcaagt gcttgacgga
     2161 aacgagctga gtcaagtgaa gtacctgaac cgataacgcg ttctttaggg aaaccagaga
     2221 atttccaagt tgagtaagtc aaaacgtcaa ctgggttagc agcaacaagg aagatacctt
     2281 tgaaaccaga ttcaacaact tgagttacga ttgatttgtt gatagcaagg tttttaccta
     2341 caaggtcaag acgagtttca cctggttttt gaggtgcacc tgcagtgatc acaacaaggt
     2401 cagcgtctgc acagtcagag tattgagctg catagatttt tttaggtgaa gtgaaggcaa
     2461 gggcgtgact aaggtcaagc gcatcaccaa cagctttttc atgcaattgt ggaatttcga
     2521 taattccaag ctcttgtgca attccttggt taacaagtgc aaaagcgtaa gatgaaccta
     2581 cagcaccatc accgacaagg ataacttttt tgtgttgttt agttgaagtc attgttttaa
     2641 acatctcctt aattttatta ggggattttc cctagacaac ttcattctat cacttttaaa
     2701 aaactttgtc acgaatatgc cttatagttc tcgatgtaaa cgttttagtg gtttagaggc
     2761 tgaaatagat gggaatttat ggtataatgt tgttacttac taattgtgaa atgaggcatt
     2821 tattaatgca ggataaaaat ttagtgaatg tcaatctgac aaaggagatg aaggcaagtt
     2881 ttatcgacta cgccatgagt gttatcgtag cgcgagctct tcctgatgtt cgagatggct
     2941 taaaacctgt tcaccgtcgc attctctacg gaatgaatga attgggtgtg accccagaca
     3001 aaccccataa aaaatctgct cgtattacag gggatgtcat gggtaaatat cacccacacg
     3061 gggattcctc tatttatgaa gccatggtcc gtatggctca atggtggagc taccgttaca
     3121 tgcttgtaga tggtcatggg aattttggtt ccatggatgg agatagtgct gccgctcaac
     3181 gttataccga ggcacgtatg agcaagattg ctctggaaat gcttcgtgat atcaacaaaa
     3241 atacagttga tttcgttgat aactatgatg ccaatgaacg ggaacccttg gtcttgccag
     3301 cgcgttttcc aaaccttttg gttaatggag caactggtat cgcggttggg atggcaacca
     3361 atattccacc tcataatctg ggtgaaacca ttgatgcagt gaagttggtc atggataatc
     3421 ctgaagtgac taccaaggac ttgatggaag tcttgcctgg accagatttt ccaactggtg
     3481 ctcttgtcat ggggaaatca ggtatccata aggcttatga aacaggtaaa ggttcgattg
     3541 tcctacgttc tcgtacagag attgaaacga ctaagactgg tcgtgagcgc atcgttgtaa
     3601 cagaatttcc ttacatggtc aataaaacca aggtgcatga gcatattgtt cgcttggttc
     3661 aggaaaaacg cattgagggt atcacagcag tacgtgatga gtcaaaccgt gaaggtgttc
     3721 gatttgttat tgaagtcaag cgcgacgcct cagccaatgt tattctcaat aacctcttca
     3781 aaatgaccca aatgcaaacc aattttggtt tcaatatgct cgctatccaa aatggtatac
     3841 cgaaaatttt gtctcttcgt cagattttgg atgcttatat cgagcaccaa aaagaagtgg
     3901 ttgttcgtcg tacacgtttt gataaggaaa aagcggaagc gcgcgctcat atcttagaag
     3961 gtctcttgat tgcgctagac catatcgacg aagtgattcg tatcatccgt gctagtgaaa
     4021 cggatgcgga agctcaagct gagttgatga gcaagtttaa gctttctgaa cgtcaaagtc
     4081 aagctatcct tgatatgcgt cttcgtcgtt tgacaggttt ggaacgcgat aagattcaat
     4141 ctgagtatga tgacctcttg gctctgattg cggatttagc agatattctt gctaagcctg
     4201 aacgtgtttc tcaaattatc aaagacgaat tggatgaagt taaacgtaaa ttttctgata
     4261 aacgccgtac agagttgatg gttggacaga tcttgagtct cgaggatgag gacttgattg
     4321 aagaatcgga tgtcttgatt accctttcta acagaggcta cattaagcgt ttggatcagg
     4381 acgagttcac tgctcaaaaa cgtgggggtc gtggtgtcca aggaacggga gtgaaagatg
     4441 atgactttgt tcgtgagtta gtgtcaacta gcacacatga tcatctgctc ttcttcacaa
     4501 acaagggacg tgtctatcgt cttaaaggtt atgaaattcc tgagtatggt cggactgcca
     4561 aagggctacc agtagtcaat ctcttgaaat tggatgaaga cgaaagtatt cagacggtta
     4621 tcaatgttga gtctgatcgc agtgatgatg cttatctctt ctttacaacc cgtcacggta
     4681 ttgtgaagag aactagtgtt aaggagtttg ccaatattcg tcaaaatggt ctcaaagcgc
     4741 tgaatttaaa ggatgaagat gagttaatca atgtcttgtt ggcagaagga gatatggata
     4801 ttatcattgg taccaagttt ggttatgcag ttcgctttaa tcaatcagcc gttcgtggta
     4861 tgagccgtat cgccactggt gtgaaaggtg ttaaccttcg tgaaggagac acagttgttg
     4921 gtgccagctt gattactgat caagatgagg ttcttattat cacagaaaaa ggatatggta
     4981 agcgtacagt cgctactgaa tacccaacaa aaggtcgtgg tggtaaggga atgcagacag
     5041 ctaaaattac cgaaaaaaat ggcttgctgg ccggtcttat gactgttcaa ggggatgagg
     5101 atttgatgat tatcactgat acaggtgtca tgattcgaac caatcttgcc aatatttcac
     5161 aaacaggacg tgcaactatg ggagttaaag taatgcgcct ggatcaagat gctcagatag
     5221 tgactttcac aacggttgcg gtggcagaaa aagaagaagt tgggacagaa aacgaaacag
     5281 aaggtgaagc ataatgtctc aaaaaaataa taaaaagaaa aacaagcgaa aaaatctgct
     5341 gacaaatatc ctagcaggat ttctgatatt actgtcactg gctttgattt ttaatactca
     5401 aattcgaaat attttcatag tctggaatac caataagtat caagttagcc aggtatcaaa
     5461 agaaaaatta gaagaaaatc aggatacaga aggcaatttt gactttgatt ctgtcaaagc
     5521 tatctcttcg gaagctgttc taacttctca atggaatgct caaaaattac cagttattgg
     5581 gggaattgca attcctgaat tggaaatgaa tttgccgatt tttaaaggac ttgataatgt
     5641 taatctcttc tacggagctg gtacaatgaa acgcgagcaa gtaatgggag aaggaaatta
     5701 tagtctagct agtcaccata tctttggtgt tgataatgct aataaaatgt tattttctcc
     5761 tttagataat gctaaaaatg gcatgaagat ttatctaacc gataaaaata aagtttatac
     5821 ttatgaaata cgtgaagtca aacgtgtgac accggatcgt gttgatgaag ttgatgatag
     5881 agatggggtc aatgaaatca cattagtaac ctgtgaagac cttgctgcta cagaacgtat
     5941 tattgtcaaa ggtgatttga aagaaacaaa agattattca caaacatctg atgaaatcct
     6001 aacagctttc aatcaaccat ataaacaatt ttattaatac aaatcagtga aatcatggat
     6061 ttcactgatt ttttaagatt ttcataaaaa tatagtaaaa tgaaataaga ataggacgaa
     6121 tcgttcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct
     6181 agtttcaatc tactataaac ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt
     6241 tgtgatataa ttatcaagaa aaaagattta ggagtttatt atgatttctt cagaatttat
     6301 ctcaaagatt gaatttgctt gcaataagaa agaaggtctt tatagtcaaa gcaaatttaa
     6361 gtatgcgatt cgttcgatgt tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc
     6421 agttggggct gacttgatta ataaaattgc accaggtagt ggacgcttcc tctttccatt
     6481 cgtttttgct tggggcttgg cctacattgt ttttttgaat gccgagttgg tcacttcaaa
     6541 catgatgttc ttgactgctg gtagtttctt aaaaaaaatc tcttggagaa aaacagctga
     6601 gattttacta tactgtacct tgttcaacct tatcggagcc ttgatagcag ggtggggctt
     6661 tgctcattcg gcagcctatg cgaatctgac acacgatagt ttcatctcag gtgttgttga
     6721 gatgaagtta ggccgctcaa atgaattggt cttgcttgag gcgattttgg caaatatttt
     6781 cgtaaatatt gcgattctgt catttatttt ggtcaaagat ggtggtgcca aactttggct
     6841 tgtgttgtca gctatttaca tgtttgtatt cttaacaaac gagcacattg cggcgaactt
     6901 tgcttctttc gcgattgtga aattcagtgt tgctgcggat tcaattgcca acttcggtgt
     6961 tggaaatatg cttcgccact ggggtgtgac tttcatcgga aactttatcg gaggaggcct
     7021 cttgatgggt cttccatatg ccttcctcaa taaaaacgaa gatacttatg tagattaaga
     7081 aaatgagcac gattgagtcg tgcttttttc attttcaaaa taaggtaaca gctatttctt
     7141 atatcaaaat atagaaaact gatatttgta aactataact caaggtgcta caatatcctt
     7201 aataaaataa tatggaggtc accttatgac ttgtgatttt aaatttgaaa ctctacaact
     7261 acatgctggt caagttgtgg ctccagctac taagtctcgt gcagtgccga tttaatcaaa
     7321 caacattttt tgtttttgat gacacgtagg aaggtgccga tatgtttgcc ttgaggaaac
     7381 cagggaacat ttatactcgt atcaccaatc ctacaacagc tgcccttgaa ggtggtgttg
     7441 aagcgctagc aacagcatca ggtatgactg cagtgactta tacgattttg gcgcttgccc
     7501 atgctggtga ccatgtagtg gctgcttcga ctatttacgg tggaaccttc aatcttttga
     7561 aagaacccct tcctcgttat ggtatcacaa caacctttgt cgatattgat aatttggagg
     7621 aagtagaagc agctatcaaa gacaatacca agcttgtctt gattgaaacc ttgggtaacc
     7681 ccttgattaa tattccagac ctggaaaaac tggcagagat tgctcataaa catcaaatcc
     7741 cacttgtgtc agacaatact tttgcaacac cttatttgat taacgtcttc tctcatggcg
     7801 ttgacattgc cattcactct gcgactaagt ttatcggtgg gcatggtaca actattggag
     7861 gaataattgt cgatagtggt cgttttgact ggacggcttc agggaaattc cctcaatttg
     7921 ttgacgaggg tccaagctgc cacaatttga gctatactcg tgatgtgggt gcagcagcct
     7981 ttattatagc tgttcgagtt caattgcttc gtgatacagg tgcagccttg tcaccattca
     8041 atgctttcct cttgctacaa agacttgaaa ccctttcact tcgtgtggaa cgccatgtac
     8101 aaaatgctga gacaattgtt gattttcttg tcaaccatcc taaggtagaa aagataaatt
     8161 atccaaaact tgcagatagt ccttatcatg ccttggctga gaaatacttg ccaaaaggtg
     8221 tcggttcaat ctttaccttc catgtcaaag gtggcgagga agaagcacgc aaggtcattg
     8281 ataatttgga aatcttctca gaccttgcta acgtggcaga tgccaagtct cttgttgttc
     8341 atccagcaac aaccactcat ggtcaattgt cagaaaaaga cctagaagca gcaggtgtca
     8401 caccaaatca aatccacttg tctatcggac ttgaaaatgt agatgatttg attgaagact
     8461 tgcgcttggc cttggaaaaa atttaaagaa aaagaagata aacagtggtt ttcgactcgc
     8521 tgtttttgat tttccttcat gcatgatata atggttacag aagtctagaa agaggaatgt
     8581 aatgaacgaa atcaaatgtc ccaactgtgg ggaagtcttt acagtaaatg aaagccagta
     8641 tgctgaactt ttgtcccaag tgagaacggc agagtttgat aaggaactac acgataggat
     8701 gaggcaggaa ctggccttgg ctgagcaaaa ggctatgaat gagcaacaga ctaaactggc
     8761 tcagaaggat caagaaattg cgcaattaca gagtcagatc caaaactttg atacagaaaa
     8821 agaattggcc aagaaagaag ttgaacagac aagccatcag gccttattgg ctaaggacaa
     8881 ggaagtacag gctttggaga accaattggc cactttgcgt ttggagcatg aaaatcaact
     8941 gcaaaagacc ctttctgacc tagaaaaaga acatgatcag gtcaaaaatc agctcctctt
     9001 gcaagaaaag gaaaatgagt tgtctttggc ttctgttaag caaaactatg aagcccagct
     9061 taaagcagct agtgaacaag tcgagtttta taagaatttt aaggctcaac aatctacaaa
     9121 agcgattggg gaaagcctag aacagtatgc agagagtgag tttaacaagg ttcgtagttt
     9181 cgcctttcca aatgcttact ttgagaagga taacaaggtc tcttcgcgtg ggtctaaagg
     9241 ggactttatc ttccgtgagt gtgatgaaaa tggagttgaa atcatttcta tcatgtttga
     9301 gatgaaaaac gaagcggacg gaacagagaa gaagcacaag aatgcagatt tttacaagga
     9361 attggacaag gaccgtcggg agaagaactg tgagtatgcc gttttggtga ccatgcttga
     9421 ggccgataat gactacttta acacagggat tgttgacgtc agccacgagt atgaaaaaat
     9481 gtatgttgtt cgtcctcaat tctttatcca gttgattggt ctcttacgta atgcggcgct
     9541 aaattcccta aaatacaagc aggagttggc cttggttcgc gagcaaaata ttgacattac
     9601 gcattttgag gaagatttgg atgcctttaa gctagctttt gctaagaact ataattcagc
     9661 ttcgactaac tttggaaaag ctattgatga aatcgacaag gccatcaaac gcatggaaga
     9721 ggttaagaaa ttcctgacca catctgaaaa ccaactccgt ctagctaaca acaaattgga
     9781 agatgtctct gttaaaaaat tgacccggaa aaatccaaca atgaaagcga agttcgaagc
     9841 actgaagggg gagtagaaag caaaaatgaa cggtattatc aacttaaaaa aagaagcagg
     9901 aatgacctcg catgatgcgg tttttaaact gcgtaagatt ttgggaacca agaaaattgg
     9961 tcatggtgga accttggatc cggatgtggt gggtgttttg ccgattgcgg ttggcaaggc
    10021 gacacgcatg gtcgagttta tgcaggacga gggtaagatc tatgaggggg aaattactct
    10081 gggttattcc acgacgactg aggatgctag tggggaagtg atcgcagaaa cccctgtttt
    10141 gtctcccttg gatgaaaagc ttgttgatga agcgattgct agcttgactg ggcctattac
    10201 ccagattccc cctatgtatt cggcagttaa ggttaatggt cgcaagctct atgagtatgc
    10261 gcgtgctggt caggaagtgg agcgtccaga acgtcaggtg accatttatc aatttgagcg
    10321 aacaagtccg atttcttatg atggccaact tgcccgattc acttttcgtg taaaatgcag
    10381 taaagggact tacatccgta ctttgtcagt tgatttgggt gaaaagcttg gttatgcggc
    10441 tcatatgtcc catttgactc gtactagtgc tgctggctta caattagaag acgctcttgc
    10501 cttggaggaa attgctgaaa aagtagaggc tgggcaatta gattttctcc atcctttaga
    10561 gattgggaca ggtgaccttg tcaaagtttt cctaactcca gaagaggcta cagaagttcg
    10621 ctttggtcgt tttattgagc tagaccaaac ggacaaagaa ctggctgcct ttgaagatga
    10681 taaattgtta gccattctag aaaaacgggg caatctctat aagccaagga aggtttttag
    10741 ctagatcgtt taggaataaa aatcgggtga tagataacaa ttgcttgata aaaccccata
    10801 ctaatagtag aatggttttg ggaattataa tattccaatt gttgcgagtt gtaggtactc
    10861 aaataatcta tatagaaatt tagaggtgtg aaatgaagca atttaaaatt ctttcagata
    10921 aatatttaga gtccattaca ggttctggtg ggaacttagg cccaggattt ggtgtgataa
    10981 ttccatgatg cgaaatgagt ttcgagaaag ggtggagcaa cttcttcaac aaaaagaaat
    11041 aaatgaaaat agtgagttga gtcacctgtt tcgtcttgct atacaaaatt tagacagaaa
    11101 tgaaaaatac caaacggtca tggccaattt gagtcaaggg ttgtcacttt acctcatgac
    11161 gcatcattac caggcaccta agtctgtcat tgattttggt ttatggattg ccaaagctcc
    11221 tagccaggaa agagggagac tggctttctt gcagatgctt gctcaaaccc tacagggctt
    11281 tcgttaaaac tgtcgaacat cagagggaag actctggtgt tttttgctga tgagactata
    11341 aattttgtaa aaaatgtgat agaatagacg acggataaaa taacggagga tagcatgcaa
    11401 aatagaccaa tcattattgg agtgacaggt ggttctggtg gtggtaaaac cagtgtttca
    11461 agagccattt tatcgcattt tcctgatgaa aagatttcca tgattgagca tgattcatac
    11521 tacaaggatc agtctcattt gacctttgaa gagcgtgtca aaaccaacta tgaccatcct
    11581 tttgcctttg atacagactt gatgatcgag cagattaagg aattgttggc agggcgtccg
    11641 gtggacatcc cgacctacga ctatacagag catacacgga gtagcaagac ctatcgtcag
    11701 gagcctcaag atgtctttat cgttgagggc attttggtct tggaggacaa gcgtctgcgc
    11761 gatttgatgg atatcaagat ttttgtggat acggatgacg atgtgcgtat tattcgtcgt
    11821 atcaagcgtg atatggagga acgtggccgt agccttgata gcgttattaa ccagtactta
    11881 ggtgtggtca aaccaatgta ccaccagttt atcgagtcaa ctaagcgtta tgctgatatc
    11941 gtcattcctg aaggggttag caataccgtg gctatcgacc tgttgacgac caagattgca
    12001 aagattttgg aagaagctcg aaacagcaaa taatcacatg tggaggcctt gcctcctttt
    12061 tctatttttc cctcataatg gtacataaat ggagattttt aggcatattt ttggtataat
    12121 aatacccata aaagagcaag taaatgaata gtaggtggag atggaaaagt atttatcggt
    12181 aacaactttg accaaatatc tgaaaatgaa attcgataaa gacccatact tggaacgggt
    12241 ctatttaact ggtcaagttt ccaactttcg taaacgacct actcaccaat atttctccct
    12301 aaaggatgac catgcagtta ttcaagcgac catctggtct gggatttatc agaaattagg
    12361 gtttgacctg gaagaaggaa tgaagatcaa tgtgattggg cgtgtacagg tctatgaacc
    12421 aagtggtagc tactccatca tcattgaaaa agctgagcct gatggggttg gggcgcttgc
    12481 gattcagttt gaacaactta agaaaaaatt gacagaagaa ggtctgtttc aagaacgctt
    12541 caagcaagct ctaccccaat tttctaagag aattggggtg gtaaccagcc gtagtggagc
    12601 cgttattcga gatattatca caaccgtcag caggcgattc ccaggtgttg acatccttct
    12661 ttatccgacc aaggttcaag gtgaaggggc tgcggaggaa attgctagaa atattgcgcg
    12721 tgctaatcaa cgggacgatt tggatttgat cattattggt cgtggaggtg gttctattga
    12781 ggatctctgg gcctttaacg aagaaattgt ggtacgagct atttttgaat ctcgtttgcc
    12841 agttatctct agtgtggggc atgagacgga tgtgaccttg gcagattttg tggcagatcg
    12901 acgcgctgca acgccaacag cggcggctga actggcaaca cctgtgacca agttggatgt
    12961 attagctcat ttgcaaaatc aggaaaaacg gatggcaacg gcagtccgaa atgttctatc
    13021 taagaaacaa gaggctttga aaaaatgcag tcagtctgtt atctttagac aacctgagcg
    13081 cttgtatgac ggttatttgc aacgcttgga ccaactgcaa ctgcgtttga aacaaagttt
    13141 gcgaactcgg atttctgata acaaacaatt agttcaagca agaactcatc aattagtaca
    13201 attatcacct gttaccaaaa tccaacgcta tcaagaccgt ttaggacagt tggacaagct
    13261 cttaggtagc caaatggcgt tagtttatga cgccaaggtt gctgaggcca agcgactttc
    13321 ggaagctttg ctcatgttgg atactagccg aatcgtggcg cgtggttatg ctattgtcaa
    13381 aaaagaagag tccattgtag attcggttga gagtttgaag aaaaaagacc aagtaacgct
    13441 tttgatgcga gatggtcaag tagaattaga ggttaaagat gtcaaaacaa aagaaatttg
    13501 aggaaaatct agcagaactg gaaaccattg tccaaagttt ggaaaatggt gaaattgctc
    13561 tggaagatgc gattactgcc tttcaaaagg gcatggtctt gtcaaaagag ctccaagcta
    13621 cgctggacaa ggctgaaaag accttggtaa aggtcatgca agaagacgga acagaaagtg
    13681 attttgaatg aaaaagcaag aaaaattagc tcttgtcgag tcggttttgg aagattttta
    13741 tggagaccag cagtttgcct ctagtttacg ggagtctgtt ctctattcta ttcatgctgg
    13801 tggcaagcgt attcggcctt ttctcttgtt agaagttctg gaagccttgc aggttgccat
    13861 caaacctgct cacgcgcagg tagctactgc cttggagatg attcatacag ggagcttgat
    13921 tcacgatgac cttcctgcta tggatgatga cgattatcga agagggcggt taaccaatca
    13981 caagaaattc ggtgaagcta tggccatttt ggctggagat gccttattct tagacccata
    14041 tgccttgatt gcgcaggcag atttgccaag tcagatcaag gtggacttga ttgccagctt
    14101 atcccttgct tcaggtagtc tgggtatggt ggcagggcaa gttttggata tggagggcga
    14161 acaccagcac ttgtctctgg aagaacttca gactattcat gccaataaga ctgggaagtt
    14221 actagcctat cccttccaag cggcagctat tatagctgaa ttgtcacctg aaatgcaggt
    14281 gaagctgaaa actgtgggtg aattgattgg acttgctttt caagtcagag atgatgtact
    14341 ggatgtgaca gctagttttg aggaaatcgg taagacacct caaaaggatc tgcaggcaga
    14401 aaaatcaacc tatcctgcct tgttgggctt ggaagagtcc attgtctttt gtaaccaaac
    14461 cctggatcaa gctaatgaaa aattggaaga aattgcccag caggttccct ttgaaacaga
    14521 atcgattgta agtgtagtag aaagtttgag aatcaatggc taaggaaaga gtggatgtac
    14581 tagcttataa acaggggttg tttgaaacga gagagcaggc caagcgaggt gtgatggctg
    14641 gcctagtcgt agcagtcctt aatggagaac ggtttgacaa gccaggagag aaaattccag
    14701 atgacaccga attaaaactc aagggggaga aactcaagta tgtcagccgt ggtggtttga
    14761 aactggaaaa ggccttgcag gtctttgatt tgtcggtgga tggcgcgact acgattgata
    14821 tcggggcctc tactggaggt tttaccgatg tcatgctaca gaatagtgcc aagttggtct
    14881 ttgcagtcga tgttggtacc aatcagttgg cttggaaatt acgccaagac ccacgagttg
    14941 tcagcatgga gcaattcaat tttcgctatg ctgaaaagac tgatttcgag caggagccga
    15001 gctttgccag tattgatgtg agtttcattt cccttagtct gattttgcca gccttgcacc
    15061 gtgtcttggc tgatcaaggt caggtggtag cacttgtcaa acctcagttt gaggcaggac
    15121 gtgagcagat tgggaaaaat ggaattattc gagatgctaa gattcatcag aatgtccttg
    15181 aatctgtaac agctatggca gtagaggcag gtttttcagt ccttggcttg gacttttctc
    15241 ccatccaagg tggacatgga aatattgaat ttttagcgta tttgaaaaaa gaaaagtcag
    15301 caagcaatca gattcttgct gagattaaag aagcagtaga gagggcgcat agtcaattta
    15361 aaaatgaata aaaaagaaag acttgaaaaa attagaagat tggtgacaga ttatcaaatc
    15421 ggcacgcaag aagaaattgt agaacatttg aaagaagcag gtatcactgc cactcaggcg
    15481 acggtatccc gagatatcaa agagttaggt attgtcaaaa ttcctttgag agacaacacc
    15541 tatgtctacg aattgccaaa atcaatcgta aaaagtctgc aactggctga agacaatatc
    15601 gaatcggctg aattgatgga taagatgatc aatctccaag ttattccagg aaatacggct
    15661 tttgtaaaag ctcagttaat cgagactttt gcagacaaga tttttagctg tttgactgat
    15721 gatagctcga ttttagtcat tgccagaagt ggaagtctag cagaggaaat ctttgaacaa
    15781 gtaaaaaatt ggtaggtcta tatgttactt gaaatttcga taaaaaactt tgccattatt
    15841 gaggctattt ccctcaattt tgaaaagggg atgactgtcc tgactggtga aacgggtgca
    15901 gggaagtcga ttatcattga tgccatgaat atgatgttgg gagctcgtgc gacgacagat
    15961 gttattcgtc atggtgcacc aaaggcagag attgaggggc ttttctcagt tgagaatagt
    16021 cgtcttttac aggaaatttt tgatgagcaa ggtttagaat taggtgatga aattatcatc
    16081 cgtcgggaaa tcttgcaaaa tggtcgtagt atcagccgtg taaatggtca gatggttaat
    16141 ctgtctgttt tgcgagctat tgggcaacat cttgtagata ttcatggtca gcatgaccat
    16201 gaggagttaa tgcgtcccca actgcatatc cagatgttgg atgaatttgg tgatgccgct
    16261 ttttgggact tgaaagaaac ctatcaaacg agttttgatg cctatcggaa aatgcgcaag
    16321 caggttctgg aagtcaagaa aaaccaacag gaacacaagg cacgtatcga aatgttggaa
    16381 tttcaaatgg cagagattga ggcagcaaac ttgcaggctg gagaagactt ggctctcaat
    16441 caagagcgag ataaactcct caaccacaaa aatattgcgg atacactgac caatgcctac
    16501 agtatgttgg acaatgaaga tttttcaagt ctggccaatg ttcgttcagc tatgaatgac
    16561 atggaaagtg tcgaagagta tgatcctgaa taccgtgaaa tttcaagctc tctgtctgag
    16621 atctactatg ttttagaaga cattagcaaa cgtttggaag ctatcattga ggaccttgat
    16681 tttgatggca atcgcctcat gcaggttgag aatcgtttgg acctccttca tactattact
    16741 cgtaagtatg gtgggactgt tgatgatgtt ttgctttatt ttgccaagat tacggaagaa
    16801 tacaatctct tgacaggcaa taatctttcg tctgaggaca tggaagcaga gcttaagaag
    16861 ttggaagtca atcttgtcaa tttggcaggt caacttgctt ctgctcgtca taatttggct
    16921 cagcaactcg aagctgagat taaacaagaa ctgcaagatc tttatatgga aaaagcccag
    16981 tttcaggttc gttttagtaa gggaaaattc agtcgtgagg gaaatgaaat ggttgagttt
    17041 tatatttcaa ccaaccctgg agaagacttt aaacccttgg ttaaggttgc ttctggaggg
    17101 gaattatctc gtctcatgtt agccattaag tctgcctttt cacgtaaaga aggcaagact
    17161 agcattgtct ttgatgaggt ggatacggga gtttcaggtc gtgttgctca agctattgct
    17221 cagaaaattc ataaaattgg tcagcatggt caggttttgg ctatctccca tttgccacaa
    17281 gtaattgcga ttgcagatta tcaattcttt attgagaaga ttagtaatga ccattcaacg
    17341 gtttcgactg ttcgtctctt gacggtcgaa gagcgagtgg aggaagttgc caagatgttg
    17401 gcaggtgatg atgtgacaga agcagccctg acgcaagcca gagaattgtt gagaaacagg
    17461 gagaaataag atgacagatt attatgtaat tggagatgtt cacggaaaag ctgggatgct
    17521 ggaagacctt cttaaaacct gggatggtca gacccagttg ctctttctag gtgatttgat
    17581 tgacagaggt gaggatagtc accgtgttct tgaaatggtc aaggacttgg tggacaatca
    17641 aggggctatc tgtttgtctg gaaaccacga gtatatgttt ttgacttggc tagatgaccc
    17701 agaagaaagt tatgaccatt atcgtcgcaa tggtggagat acaaccatta actctatcct
    17761 aggtcgtccc ttggatgcac cagttgatgg agtagaagat gccaagcggg ttgccgctga
    17821 agcggcagac ttggtcgaat tcattcgtca aatgccattt gtagtagaga cagacaagta
    17881 tatctttgtt cacgcaggta ttgatttgac cttggacgac tggcatgaaa caacagatta
    17941 taaaaaagta tggcttagaa aaccattcca cggagctgaa aatcatactg gaaaaaccat
    18001 tgtcttcggt catacaccgg tctatggttt gttacagcaa gaacgcggta catctgagct
    18061 ttggactaca gaagatggca agattggaat ggatggagga gctgtttatg gtggtgtcct
    18121 tcacgggatt gtctttacag accaaggaat gacagaacac cactttatcg aaaatgacgg
    18181 ctttgtcgct gaagattagt actcctagca gggtatggtc ttgtcaaaat atcaaaaaca
    18241 atttataata aatagatacc ctgaaaggaa gagaatcatg aacttagaag aattgaaaaa
    18301 acgacaggag aagatccgta acttctctat tatcgcccat attgaccacg gaaaatcaac
    18361 tctagcagac cgcattttgg aaaaaacaga gacggtttca agtcgtgaaa tgcaggccca
    18421 gcttttggat agcatggagc tagagcggga acgtggaatt actattaagt tgaatgccat
    18481 cgagttgaat tacactgcaa aagatgggga aacttatatt ttccacttga ttgacacacc
    18541 agggcacgtt gactttacct atgaagtttc acgttcgcta gctgcctgtg agggtgctat
    18601 tttggtggtc gatgcggctc aaggaattga ggctcaaact cttgccaacg tttatctggc
    18661 tttggataat gatttggaaa tcatgcctat cattaataaa attgacctgc cggctgcaga
    18721 tccggagcgc gtgcgtacag agattgaaga tgtgattggt ttggatgcca gtgaagcagt
    18781 tttggcttct gccaaggctg gtattgggat tgaagaaatc ctcgagcaaa ttgtagaaaa
    18841 agtaccagca ccaacgggtg atgtgacggc gccacttaag gccttgattt tcgactctgt
    18901 ttacgatgct taccgtgggg ttatcctcca agtacgtgtc atggacggag tggtcaaacc
    18961 tggtgataag attcagctca tgagcaatag taagaccttt gatgtggccg aagtcggtat
    19021 ttttacacca aaagcggttg gtcgtgattt ccttgcgact ggtgatgttg gttacattgc
    19081 ggcgtctatc aagacggttc aggatactcg tgtgggtgat accgttacct tggcaaccaa
    19141 tcctgcggca gaaccattac atggttataa gcagatgaat cctatggtct ttgcgggtct
    19201 ctacccaatc gaatcaaaca agtacaatga cctgcgtgaa gcgcttgaaa aattgcaact
    19261 gaatgatgct agtcttcagt ttgaaccaga aacatctcag gcacttggat ttggtttccg
    19321 ttgtggattt cttggacttc tccatatgga tgttatccag gaacgtttag agcgtgagtt
    19381 caatattgac ctcatcatga cagctccgtc tgttatttac aaagttaatt tgaccgacgg
    19441 tgagtctatg gatgtgtcta acccatctga gtttccagac ccaactaaga ttgcgaccat
    19501 tgaagagcct tatgtcaagg cgcaaatcat ggtaccacag gagttcgtcg gagcagtaat
    19561 ggagctagct cagcgtaagc gtggggactt tgtgactatg gactatattg atgataaccg
    19621 tgtcaatgtt atctatcaaa ttcctcttgc tgaaattgtc tttgacttct ttgataaact
    19681 taagtcttca acacgtggtt atgcaagctt tgactacgaa ttgtcagaat atcgcccatc
    19741 taagctggtg aaaatggata tccttctcaa tggagataag gtggatgctc tcagctttat
    19801 cgttcacaag gactttgcct acgaacgtgg gaaactcatc gttgataaac tcaagaaaat
    19861 catccctcgc caacaatttg aagttccaat ccaagcggct attggacaca agattgtcgc
    19921 tcgtactgat atcaaggccc ttcgtaagaa cgtacttgct aaatgttatg gtggtgacgt
    19981 ttctcgtaag cgtaaactcc ttgaaaaaca aaaagctggt aagaaacgca tgaaatccat
    20041 cggatcagtt gaagttccgc aagaagcctt cctcagcgtc ttgagtatgg atgaagaata
    20101 agttatcaga aatgcctttc cttgttcaca ggaaatttat ataagaatca atagtaaagc
    20161 aggcttagat ggtctgcttt tttagttttt atactcttcg aaaatctctt caaaccacgt
    20221 catcgtcgcc ttaccgtatg tatggttact gacttcgtca gtttcatcta caacctcaaa
    20281 accatgtttt gagctgactt cgtcagtttc atctacaacc tcaaaaccat gttttgagct
    20341 gacttcgtca gtttcatcta caacctcaaa actgtgtttt gagtaacctg cggctagctt
    20401 cctagtttgc tctttgattt tcattgagta ttagaacaga aaaatgcttg gagtatttgt
    20461 ttgtgtgttt atttttatat aacaaactat aaacaaaaca aaaatataaa aaagagacaa
    20521 aaaagaacag aaagtaatta acaacgattt catatagtgt tatacttata gcataaagtt
    20581 aatggaaaga agggaaaacc ttatggtatt agattatttc tttgacaaaa accttgtgtt
    20641 ttgcttagaa gcggataatc aagaataact ctttgatcag gtagcaagct tgttggagga
    20701 acgagaaatt gtaactccaa cttatcgtga agccttgatc acgcgtgaaa agtcatttcc
    20761 aactggttta gatatggaat ttctaggaaa ggacttgcca aatgtagcga ttcctcacac
    20821 agatattgtt cataatttgg ctgaaaaagt tgtggtcgtt cgattagaga aaccggtgac
    20881 tttccataat atgattgcgc cagataagga agtagaagta tccttgctct tctttatcat
    20941 taataattca agttcaagtc aaacgaacat tcttgctcag ttaatggact tcttcacagg
    21001 aaatggtcat cttgaagacc tatcaaaaat ttctgaacca gaagcccttt atgcttacat
    21061 tgctgaagca accgcttaat cttgtctatt aaaaaataaa atcggaggaa atccaaatga
    21121 ttaaaattct tgctgcctgc ggtgcaggtg ttaactcaag tcaccaaatt aaaagtgctc
    21181 tagaagaaga actttcaaac cgtggttacg atgttcactg tgatgcagtt atggtgaaag
    21241 atgtaaacga agaccttatg aaaggttacg atatctttac accaatcgct gcaacagacc
    21301 ttggttttga accaggtatc ccagttatcg aagctgggcc aatcttattc cgtatcccag
    21361 caatgagcgt tccagtattt gacaatatta gacttcctgc gaaacaaaac atggtatagt
    21421 agttctatga atgatgaagc aagtaaacaa ctaac
//
LOCUS       DBEJZV010000033        21405 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.33, whole genome shotgun sequence.
ACCESSION   DBEJZV010000033 DBEJZV010000000
VERSION     DBEJZV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21405
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.33"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            344..2272
                     /gene="glgB"
                     /locus_tag="ACL3S0_001655"
     CDS             344..2272
                     /gene="glgB"
                     /locus_tag="ACL3S0_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGR1312535.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKNFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNPKGVENEK"
     gene            2262..3404
                     /locus_tag="ACL3S0_001656"
     CDS             2262..3404
                     /locus_tag="ACL3S0_001656"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGR1312536.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3394..4533
                     /gene="glgD"
                     /locus_tag="ACL3S0_001657"
     CDS             3394..4533
                     /gene="glgD"
                     /locus_tag="ACL3S0_001657"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGR1312537.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4530..5963
                     /gene="glgA"
                     /locus_tag="ACL3S0_001658"
     CDS             4530..5963
                     /gene="glgA"
                     /locus_tag="ACL3S0_001658"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGR1312538.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            6022..6393
                     /locus_tag="ACL3S0_001659"
     CDS             6022..6393
                     /locus_tag="ACL3S0_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HGR1312539.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6338..6667
                     /locus_tag="ACL3S0_001660"
     CDS             6338..6667
                     /locus_tag="ACL3S0_001660"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGR1312540.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            6676..7791
                     /locus_tag="ACL3S0_001661"
     CDS             6676..7791
                     /locus_tag="ACL3S0_001661"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGR1312541.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     VSGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGILDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(7788..8234)
                     /locus_tag="ACL3S0_001662"
     CDS             complement(7788..8234)
                     /locus_tag="ACL3S0_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGR1312542.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8398..9702
                     /gene="eno"
                     /locus_tag="ACL3S0_001663"
     CDS             8398..9702
                     /gene="eno"
                     /locus_tag="ACL3S0_001663"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGR1312543.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(9839..10285)
                     /locus_tag="ACL3S0_001664"
     CDS             complement(9839..10285)
                     /locus_tag="ACL3S0_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR1312544.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTRKPAHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(10185..11058)
                     /locus_tag="ACL3S0_001665"
                     /pseudo
     CDS             complement(10185..11058)
                     /locus_tag="ACL3S0_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            11229..11384
                     /locus_tag="ACL3S0_001666"
                     /pseudo
     CDS             11229..11384
                     /locus_tag="ACL3S0_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            11584..14859
                     /gene="rexB"
                     /locus_tag="ACL3S0_001667"
     CDS             11584..14859
                     /gene="rexB"
                     /locus_tag="ACL3S0_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGR1312545.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFFEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            14856..18506
                     /gene="addA"
                     /locus_tag="ACL3S0_001668"
     CDS             14856..18506
                     /gene="addA"
                     /locus_tag="ACL3S0_001668"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGR1312546.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGCQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            18721..19899
                     /locus_tag="ACL3S0_001669"
     CDS             18721..19899
                     /locus_tag="ACL3S0_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312547.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            20108..>21405
                     /locus_tag="ACL3S0_001670"
     CDS             20108..>21405
                     /locus_tag="ACL3S0_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR1312548.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSESEVSNQKSSVATSTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKG"
BASE COUNT         6587 a         4036 c         4570 g         6212 t
ORIGIN      
        1 gaaatcgatt tgactgtcct gatcgatttg tcctgttatt atttcatttt actatatata
       61 gtacattgaa gttaaaatag tacactttga tttctaagac attgttagaa attagattaa
      121 attccttaat cgatttgcgc atgttttatt tcatttcact atagtagaaa aagaaaggcg
      181 ttttcgcaat tttttgaaaa aatattgatt tacaattgaa cgagtaagtg aacttgttgt
      241 agattttcaa aataattaaa gaagtatagt aatttacttg aatcttctct aaaaaggtag
      301 tataataaaa gcatagaaaa cgcttacagg agaaggggag tatatggata atagagaagc
      361 attaaaaacc tttatgacgg gtgaaaattt ttatctccaa cattatctag gagcacatag
      421 ggaagaacta aatggagagc atggctatac cttccgtgtt tgggcaccta atgctcaggc
      481 tgttcacttg gttggtgatt ttaccaactg gattgaaaat cagattccaa tggtaagaaa
      541 tgattttggg gtctgggaag tctttaccaa tatggctcaa gaagggcata tttacaaata
      601 tcatgtcaca cgtcaaaatg gtcatcaact gatgaagatt gacccttttg ctgtcagata
      661 tgaggctcgt ccaggaacag gggcaatctt aacagagctt cctgagaaga aatggaagga
      721 tggactttgg ctggcacgaa gaaaacgttg gggctttgaa gagcgtcctg tcaatattta
      781 tgaagttcac gctggatcat ggaaaagaaa ttctgatggc agtccttata gttttgccca
      841 gctcaaggat gaactcattc cttatctcgt tgaaatgaac tatactcata ttgagtttat
      901 gcccttgatg tcccatcctt tgggcttgag ttgggggtat cagcttatgg gttacttcgc
      961 tttagagcat gcttatggcc gaccagagga gtttcaagat tttgtcgagg agtgtcatac
     1021 ccataatatt ggggttattg tggactgggt accaggtcac tttaccatca acgatgatgc
     1081 cttagcttat tatgatggga caccgacttt tgaataccaa gaccataata aggctcataa
     1141 ccatggttgg ggtgccctta attttgacct tggaaaaaat gaagtccagt ccttcttaat
     1201 ttcttgcatt aagcattgga ttgatgtcta tcatttggat ggtattcgtg tggatgctgt
     1261 tagcaacatg ctctatttgg actatgatga tgctccatgg acacctaata aagatggcgg
     1321 aaatctcaac tatgaaggtt attatttcct tcaacgcttg aatgaagtta ttaagttaga
     1381 atatccagat gtgatgatga ttgcagaaga aagttcgtct gcaaccaaga ttacgggaat
     1441 gaaagagatt ggtggtctag gatttgacta caaatggaac atgggctgga tgaatgatat
     1501 cctccgtttc tacgaagaag atccgattta tcgtaaatat gactttaacc tggtgacttt
     1561 cagctttatg tatgttttca aggagaatta tctcttgcca ttctcgcacg atgaagtggt
     1621 tcatggcaag aagagtatga tgcataagat gtggggagat cgttacaatc aattcgcagg
     1681 cttgcgcaat ctctatacgt accaaatttg tcaccctggt aagaaattgc tcttcatggg
     1741 tagcgaatac ggtcaattcc tagaatggaa atctgaagaa cagttggaat ggtctaacct
     1801 agaagaccca atgaatgcta agatgaagta tttcacttct cagctaaacc agttttacaa
     1861 agatcatcgc tgtctgtggg aaatcgatac cagctatgat ggtattgaaa tcattgatgc
     1921 ggataatcga gaccagagtg ttctttcctt tattcgtaag ggtaaaaagg gagaaatgtt
     1981 agtctgtatc tttaacatgg tacctgttga gcggaaaaat tttacaatcg gactacccgt
     2041 tgcaggaatt tacgaagaag tatggaatac tgagttggaa gagtggggag gcgtttggaa
     2101 agaacataat caaactgttc aaacgcaaga aggactatgg aaagattatg agcagacctt
     2161 aacctttacc ctaccggcta tgggagcaag tgtatggaaa atcaaacgtc gcttgaaatc
     2221 tactaaaacc gtcacaaata aaaacccaaa aggagtagaa aatgaaaaat gaaatgttag
     2281 ctttgattct tgctggtggg caaggaactc gtctcggtaa actcactcaa agcatcgcaa
     2341 aaccagctgt gcaatttggt gggcgctacc gtatcattga ctttgcccta tcaaactgtg
     2401 ccaactcagg gattcataat gttggggtcg ttacacagta tcaaccactt gctctcaaca
     2461 accatattgg gaatggttca agctggggac tagacggtat taattcaggt gtctctattc
     2521 ttcaacctta ttctgcaagt gaaggaaatc gttggtttga gggaactagt cacgctattt
     2581 accaaaatat cgactatatc gacagtgtca atcctgagta tgtcttgatt ttgtctgggg
     2641 accacatcta caaaatggac tatgatgata tgctccagtc tcataaggat aataatgcca
     2701 gcttgacagt agcagtttta gacgtccctc ttaaagaagc aagccgtttt ggtatcatga
     2761 acacagatgc taacaatcgt attgttgaat ttgaagaaaa accagctcaa cctaaatcta
     2821 caaaagcttc tatgggaatc tacatttttg attggcaacg ccttcgtaat atgttagtcg
     2881 ctgctgaaaa gagcaaggtt ggcatgtcag actttggtaa aaatgtcatt ccaaattacc
     2941 ttgagtcagg tgaaagtgtt tatgcttacg aatttagtgg ttattggaaa gatgttggta
     3001 ctattgagtc actttgggaa gcgaacatgg agtatatttc tccagaaaat gccttggata
     3061 gtcgtaaccg tcaatggaag atttactcaa gaaacttgat ttcaccacca aacttcctcg
     3121 gggcaaatgc tcatgtggaa gactcattag ttgtagacgg atgtttcgtt gatggaactg
     3181 ttaaacattc tatcctttca acaggcgcgc aagttcgcga aggagcggaa gtccttgatt
     3241 cagttatcat gagtggagct atcattggtc aaggagctaa gattaaacgt gccattattg
     3301 gtgaaggtgc gattatttct gacggtgtcg aaattgatgg aacagatgaa gtacaagttg
     3361 taggatataa tgaagtagtg ggggtagcaa cagatgaaga ttgataaata ttctgccatt
     3421 ttaggaaata cagttggttt tcacaatatg tcgacattga cggaccaccg tccagtagca
     3481 agtttgccat ttggtgggaa atatcgtttg attgacttcc cactttcaag ccttgctaat
     3541 gcaggtgttc gtagtgtctt tggtattttc cagcaggata atatcagctc agtatttgac
     3601 catattcgtt caggacgcga gtggggctta tcaacccttc ttagccatta ctatctagga
     3661 atttacaata cccgtgtaga aagtagtaca gttggaaaag aatactacca acagcttctt
     3721 acttatttga aacgttctgg ctcaaaccaa acggttgccc tcaactgcga tgttcttatt
     3781 aacattgatt tgaaccaagt tttccaccta catagtacaa caaaagagcc tatcactgta
     3841 gtttataaaa aactagctaa gaaagatatt tcagaagtaa atgcaatctt ggatgtagat
     3901 gaaacagacc atgttctttc tcataaactc tttgatagca agtcaacagc tgaaacgttc
     3961 aatatgtcta cagatatctt tgtcgttgat acaccttggt tgattgaaca cttggaagaa
     4021 gaagctaaaa aagaacatcc agagaaattg cgctatgttt tacgggattt ggctgtaaaa
     4081 gagggagctt tcgcctacga gtacacgggc tatctagcca atattcactc tgttaaatct
     4141 tattatcaag cgaatatcga tatgcttgaa tcacaaaaat tctattctct tttctcacca
     4201 aaccaaaaga tttatacaaa ggtcaaaaac gaagagccaa cttactatgc taatacatct
     4261 aaggtaagca cttctcagtt tgcctctggt agtattattg aaggtcaagt agctaattct
     4321 gttctatcac gtaatattca tgtccataag gatagcttgg ttaaagatag cctgctcttc
     4381 cctcgtgttg ttattggaga aggggctcag gtcgaatatg ctatcttgga caaaggggtt
     4441 gaagttgagc ctggtgttgt gattcgagga actgcagaac atccagttgt ggttaagaaa
     4501 ggtgctaaag taacagagga tattcattca tgaaaatttt atttgtagca gcagagggtg
     4561 cacccttttc aaaaacaggt ggtttgggag acgtcattgg cgctcttcca aaatcactgg
     4621 taaaagctgg gcacgaagtt gcagtgattt taccctacta tgatatggta gaggctaaat
     4681 ttggaaatca gattgaagat gtgcttcatt ttgaggtgag cgttggttgg cgcagacagt
     4741 attgtggaat taagaaaaca gtattaaatg gtgtaacctt ctactttatt gacaatcaat
     4801 attatttctt ccgtggtcat gtttacggtg attttgatga cggagaacgc tttgcctttt
     4861 tccaactggc tgccattgag gctatggaaa ggattgactt tattcctgat cttctccatg
     4921 ttcatgacta ccatacagct atgattcctt tcttgttgaa ggaaaaatac cgttggattc
     4981 aagcctatga ggacattgaa acagttttaa ccattcataa tttagaattc caaggacaat
     5041 tttcagaagg aatgttgggt gatttgtttg gagttggcct tgaacgttac gctgatggca
     5101 cccttcgatg gaacaactgt ctgaactgga tgaaggcagg tattctctat gcgaaccgtg
     5161 tttcaaccgt ttcacctagc tatgctcatg aaattatgac tagtcagttt ggatgtaatt
     5221 tggatcagat tcttaaaatg gagtctggta aagtatctgg tatcgtgaat gggattgatg
     5281 ctgatcttta taatcctcag acggatgctc ttttagacta tcatttcaat caggaagatt
     5341 tgtctgggaa agccaaaaat aaggcaaaat tgcaagaaag agttggcttg cctgttagag
     5401 cagacgttcc actggtggga attgtttctc gtttgacacg tcaaaaaggt tttgatgtgg
     5461 tggtcgaaag tcttcaccat atcttgcaag aagatgttca gattgttctt ttgggaactg
     5521 gcgatccagc ctttgaagga gctttctcat ggtttgctca gatttaccca gacaagctat
     5581 caacaaatat cacttttgat gtcaaacttg ctcaggaaat ctacgctgct tgtgacctct
     5641 tcctcatgcc aagtcgtttt gaaccgtgtg gcttgtctca aatgatggct atgcgttatg
     5701 gaaccttgcc attggtccat gaagttggag gcttgcgaga tacagttcgc gctttcaatc
     5761 caatcgaagg aagcggtact ggctttagct ttgacaatct atctccttat tggttaaatt
     5821 ggactttcca aacagcattg gacttgtata gaaaccatcc agacatttgg agaaacctac
     5881 aaaaacaagc tatggagagt gacttctcat gggatacagc ctgcaagtca taccttgact
     5941 tgtaccatag tttagttaat taatagataa aatcgtatga tgacttcata cgatttttag
     6001 gctgtttaga gaggagaact gatgtctcaa gtaaaaggct tgtgtgtttt ggatgtagat
     6061 ggaaccttaa tcctagaaga agtgattgat cttttaggga gagaggcagg tcatgaggcg
     6121 gaaatttcgc agattacaag tcgagcaatg cgaggagagt tggtctttga aagcagttta
     6181 agaaaaagag tgtccttgtt ggaaggtctt cctattttgg tctttgataa cgtcttcaac
     6241 tcaattcatc tatcgctaaa tgtcccagag ttcatctcta ttctccaaaa gaatggcatc
     6301 ctagttggtc tggtgtctgg tggatttaca ccaatagttg gagagattag caaaatccct
     6361 tggtattgcc tatttcactg ccaaccagct tgaagtcaaa gaaggtcttt taacaggaaa
     6421 attagttgga caaattataa gtccccaggt caaaaaagaa actctggaaa aatggagaaa
     6481 gaaactaaaa ctttctaaag aaagaacggt ggcaatcggt gatggggtca ataatctatt
     6541 aatgttgaag tcggcggagt taggaatcgc cttttgtgcc aaagaagtgc tcaaaaaaga
     6601 aataccacat catgttgaca agagggattt tttagaagtt cttcctttga ttgactgttt
     6661 agaatgaggg aaaatatgaa gattgtaatt gcaccggatt cgtttaagga aagcttgaca
     6721 gctcaacagg tagctgaagc aataaaaaga ggcttccaac aatcgatagc agatgtagaa
     6781 tgtctcctct gccctgttgg tgatggggga gaaggtactg tagatgctat ccgacattct
     6841 cttgacctaa aagaaaaatg gatccaagtg acagaccctt ttggacaaaa agaagccatg
     6901 cgctattttc aaaaagggga actggcacta tttgaagtag ctgacttggt tggtcttgga
     6961 aaaattccgc tagagaaacg aaatccactt caaatccaaa cttgtggtat tggagagttg
     7021 attctccatc tcatttctaa agggattaaa gatatttata tcggtgttgg tggcacggcc
     7081 agtaatgatg gaggactggg gattgctgct ggtttaggtt atcaatttta tgatagggat
     7141 ggaaatgtct tgcctgtttc cggtcaatcc ttattaaact tagcttctgt ttcaacagaa
     7201 aattgctata aaattcctga aggtgttcaa attcatattc tagcagatgt cgtgagtccc
     7261 ttatgtggtc atcaaggtgc gacttacact tttggcaatc aaaaaggtct acatccgact
     7321 atgtttgcag tcgtagatca ggcgatccaa gatttttatg aaaaattctc acctgcaaca
     7381 ttagaaatta aaggagcagg agcaggtgga ggccttgctg gtggtttgtg tgcctttgct
     7441 caggcaagta tcgtgtctgg aattgatacc tgcttggact taatcaactt tgataagaaa
     7501 gtttcagatg ctgacttggt tgttgttgga gaaggaatac ttgacagtca aagctttgct
     7561 gggaaagcgc ctataggtgt tgcaaaaaga acccctgttg gagttcctgt tattgctatt
     7621 tgcggtagtc ttgctgaaga tttacctccc ctaccatttg aaaatatcca agctgtcttt
     7681 tctattttgg agaaaagtga acctttagaa gatagtttga aaaatgccag tctctatctg
     7741 gagcgcacgg ctgccaatat tgggcactta ttaaatatgt gcaagattta gctaaaccat
     7801 ttcttccata aggatgtttt ggctggttct tcctttttaa cttcccaaag ttttggaaaa
     7861 gcaagtcgaa ggtctttttc ttctacttga actggtgcat tgctatgaat aaccaggccg
     7921 aaaggagaag taatatgctc ttcagatact atggtggctt gactatcagt ttcttttgct
     7981 tcttttaagt agaaaacttg cttatcaaat tcgatagttg gtgaaatctt cacaaatagt
     8041 ggctctgctt tttcctgaag gttttctaaa ataaataaaa agcctttttc taactgaggg
     8101 ctatttgctg tgtcaatatc tacatatcca agaactcttt cctcaaaagt accaagatag
     8161 cgtctttgct catccggatt tatttttaac ccaccatgag ctttttcaag taattgtttt
     8221 gataaatctg tcatgaaaac agtatatcat aaaagttaga ataaaacaga caaaagaaag
     8281 cgattacttt ataaagttaa ggaaaagttg cacaaagata acgttttttc ttgaaaaagg
     8341 aggggtttta aggtattata gaggtgtaaa aaatttaact cataaggaga gtaaaaaatg
     8401 tcaattatta ctgatgttta cgctcgcgaa gtcctagact cacgcggtaa cccaacactt
     8461 gaagtagaag tttacactga atcaggtgct ttcggacgtg gtatggttcc atcaggagct
     8521 tctactggtg aacacgaagc agttgaactt cgcgacggtg acaaatctcg ttacggtggt
     8581 cttggtacac aaaaagctgt tgacaacgta aacaacatca ttgctgaagc tatcattggc
     8641 tacgatgtac gtgatcaaca agctattgac cgtgctatga tcgcacttga cggtactcct
     8701 aacaaaggta aattgggtgc gaatgcaatc ctcggtgtgt ctatcgctgt agctcgtgct
     8761 gctgctgact accttgaaat cccactttac agctaccttg gtggattcaa cactaaagtt
     8821 cttccaactc caatgatgaa catcatcaac ggtggttctc actctgacgc tccaatcgct
     8881 ttccaagagt tcatgatctt gccagttggt gcgccaacat ttaaagaagc ccttcgttac
     8941 ggtgctgaaa tcttccacgc tcttaagaaa atccttaaat cacgtggttt ggaaactgcc
     9001 gtaggtgacg aaggtggatt cgctcctcgt ttcgaaggaa ctgaagatgg tgttgaaact
     9061 atccttgctg cgattgaagc tgctggatat gtaccaggta aagacgtatt tatcggattt
     9121 gactgtgctt catcagaatt ctacgataaa gaacgtaaag tttacgacta cactaaattt
     9181 gaaggtgaag gtgctgctgt tcgtacatct gcagaacaaa tcgactacct tgaagaattg
     9241 gttaacaaat acccaatcat cactattgaa gatggtatgg atgaaaacga ctgggatggt
     9301 tggaaagctc ttactgaacg tcttggtaag aaagtacaac ttgttggtga cgacttcttc
     9361 gtaacaaaca ctgactacct tgcacgtggt atccaagaag gtgctgctaa ctcaatcctt
     9421 atcaaagtta accaaatcgg tactcttact gaaacttttg aagctatcga aatggctaaa
     9481 gaagctggtt acactgctgt tgtatcacac cgttcaggtg aaactgaaga ttcaacaatc
     9541 gctgatatcg cagttgcaac taacgcagga caaatcaaga ctggttcact ttcacgtaca
     9601 gaccgtatcg ctaaatacaa ccaattgctt cgtatcgaag accaacttgg tgaagtagct
     9661 gaatatcgtg gattgaaatc attctacaac cttaaaaaat aaaatagttc agtgaactat
     9721 tttatcccga accatgaaat tcaaaagttc ggccgttgat ttaacaacgt ttctagcccc
     9781 tcggatttta tccgaagggc tatttttgta tttagaggac aaaaaaggga caaaactttt
     9841 aaaaaatctt tttcataact ttatccagta cattgattgc ttcatctttc atgttctttg
     9901 tgacgtgggt gtagatggaa gtagtgactt cagagtcgga atgaccaacc ctgtccgtga
     9961 ttgtttttaa aggaatttta ttttctgata agatgctaat agtggtgtgt ctgaagatgt
    10021 gaggggacag atgtttggga attggttttt taaggcgttc gtttgctcgc tggagagact
    10081 tactcaagat agaactatga gctggttttc ttgtattggt aacaaaaata cggtcgcttt
    10141 tgtgccaatt cttatcggtt gtttcgctta gacaatttat atagtcaatt gaaacaagaa
    10201 caagacaaaa gagcctcgta aaaggtattg caacttggta ataccttttt gaggtgcttt
    10261 ttgatatgag cccatgtttt ctcaatagga ttgtactcag gcgagtaggg aggaagaggt
    10321 aaaagtttat gcccaaactc ttcgcataaa agttctagat tccccattct atggaatctt
    10381 acattcttcc ccattctatg gaatcttgca ttatccataa taataaccga tggtgtggtt
    10441 aatgttggta agagaaattt ctgaaaccaa gcttcaaaaa agtcgctcgt catcgtctct
    10501 tcgtaagtca ttggagcgat taactcacca tttgttagac ctgcaaccaa agaaatcctc
    10561 tgatatcttc ttccagatac tttgcctctt attaactgat cttttaatga gcgaccatat
    10621 tctcgataaa aataagtatc gaatcctgtt tcgtcaatct aaacaggtgc taggtgcttt
    10681 aaactattaa aattcttaag aaataaggct actttttctg ggtcttgttc atagtaggtg
    10741 tggttctttt tttcgagtgt agcccatagc tttgagcgca tagtggatgg tagttggatg
    10801 acagccaaag tcagaagcta tttcagtcaa ataagcgtct ggattgtcag taagatagtt
    10861 tttaagtcta tctctatcaa cttttcttgg ttttgttcct tttacttggt ggcttagctc
    10921 tcctgttttc ttttttagct ttaaccagcc ataaatggta ttacgtgaga tttggaaaac
    10981 gtgtgatgct tctgttatac tacctgttcg ctcacaataa gagagaactt ttttacgaaa
    11041 atctattgaa tatgccataa gaagattata ccacattgtg tcctattttt ggttcatttt
    11101 actatagtag attgaaataa gatacgaaca gcttgattag ggaaatcaaa ttaatttcta
    11161 gaaatatttt agcatccacg gtgtactgtt atagtttcaa tttactatag ttcaatcatt
    11221 ctatcaagaa tattgaatat ataaaggcac gtaatattaa aacttcttct gatatcgaat
    11281 tagagtccga tgttgatggc gataaatcag acaatctacc cgtcgacatt aagatactgg
    11341 gacaacacat tgaagtgtat tccgtaccta agaaacaatc ataaaactca aagccttgtt
    11401 accgaggctt ttttattatg tgattttcag tagccagact tattctatct aatacaagta
    11461 aagctaagta tttaagattt agcagatgat gaagaaaaga aaggatggcc taaatatttt
    11521 aacagattta cgaggctaat catggtataa tatagggtga tgaaaaattc caacgaggct
    11581 gagatgaaat tactttatac tgatattcgg acttctttga cagaaattct aacaagagag
    11641 gcagaagagc tagttgcagc tggcaagcgg gtcttctaca ttgcccccaa ctctctttct
    11701 tttgaaaagg aacgcgccgt gctggaatac ttgtcccagc aggcttcttt ttcgattacc
    11761 gtcacgcgct ttgctcaaat ggctcgctat ctggtcttga atgatttacc agctaaaact
    11821 actcttgatg atatcggtct tgggttggcc ttttacaaat gccttgccga actcgatccc
    11881 aaggacttgc gtgtttatgg cgctattaag caggatcctc aattgatcca gcagttaatt
    11941 gagctttacc atgagatgac caaatctcag atgagttttt tggacttgga gaatttaaca
    12001 gatgaggata agagggcgga tttactcttg atttttgaga aagtaacagc ctatcttaat
    12061 caaggtcagt tagcccaggg aagtcagttg tcccatttga ttgaggctat tgagaatgac
    12121 aaggtaagta gtgattttaa tcaaatcgcc ttggtcattg acggctttac tcgtttttct
    12181 gctgaggaag agcgggttgt ggacttactt cacggcaaag gtgttgagat tgttatcggg
    12241 gcttatgcta gtaagaaagc ctataccagt ccttttagcg agggcaatct ctaccaagcc
    12301 agcgtaaaat ttctccatca tctggcttct aaataccaaa cgcctgctca ggactgttct
    12361 caaactcatg agaagatgga tagttttgac aaggcctctc gtttgttgga gtcttcttat
    12421 gacttttcag aactcgcttt ggatgtcgat gagaaagacc gtgaaaattt acaaatctgg
    12481 tcttgtttga cgcaaaagga ggagttggag ctagtagccc gtagtattcg tcagaaatta
    12541 catgagaact cagacctgag ctacaagcat tttcgtattc tcttggggga tgtagcttct
    12601 taccagttat ctctcaaaac catttttgac cagtatcaaa ttccttttta tcttggtaga
    12661 agcgaagcca tggctcatca tcccttgact cagtttgtcg agtctatttt agctttaaaa
    12721 cgttaccgtt ttcgtcagga ggatttgatt aatcttctta gaactgattt gtatactgac
    12781 ctcagtcagt ctgatattga tgcttttgag caatatatcc gctatcttgg tatcaatggc
    12841 ttgccagcct ttcagcaaac cttcaccaaa tcccaccatg gaaaatttaa tcttgagcgt
    12901 ttgaatgtcc tccgcctgag aattttagca cctcttgaaa ccctctttgc cagccgaaaa
    12961 caaaaggctg aaaacctcct acaaaaatgg agtgtctttc taaaagaagg agctgtgacc
    13021 aagcagttac aagatttgac aaccactttg gaagctgtag aacaggaaag acaagccgaa
    13081 gtttggaagg ctttctgcca tgttttagaa caatttgcga ctgtttttgc tggttcacag
    13141 gttagtctgg aagacttcct agccttgctc cattctggaa tgagtttgtc ccaataccgt
    13201 accattccag caacagtgga cactgttctg gtgcagagtt acgatttgat tgcaccattg
    13261 actgctgact ttgtctatgc tattggacta actcaggaca atttaccaaa aatttctcaa
    13321 aacaccagtc ttctgacaga tgaagaaagg caaaatctaa accaagcgac cgaagaaggc
    13381 gttcaattac tgattgccag cagtgaaaat ctcaagaaaa atcgctacac tatgctttcc
    13441 ttggtcaatt ctgctcgtaa gcagttgttc ttgtcggctc caagcctttt taacgaaagt
    13501 gaaagtaagg aatctgccta tcttcaagag ttgatccatt ttggatttag gcggagagag
    13561 aagaggatga atcacaaagg actgtctaag gaggatatgg ggtcctatca cagtcttttg
    13621 tctagtctgg ttgcctatca ccagcagggt gagatgagcg atactgagca agatttgact
    13681 tttgtcaagg ttctgtcgcg tgtcataggt aaaaaactag atcagcaagg tctggaaaat
    13741 ccagccatcc caatcagtcc aagcagcaag accttagcca aggacacctt gcaagctctc
    13801 tatcctgcca aacaggagtt ttacctgtct acgtcgggtt tgacagagtt ttatcgcaat
    13861 gaatacagtt atttcctacg ctacgtttta ggcttgcagg aggaattacg tttgcgtcct
    13921 gatgcccgta gtcacgggaa tttcttgcat cgtatctttg aacgcgcctt gcagttgcct
    13981 aatgaagatt cctttgacca acgtctagaa caagctattc aagaaaccag tcaagaacgc
    14041 gaatttgaag ctatttatca agaaagtttg gaagcccagt ttaccaagga agttttgctt
    14101 gatgttgcac ggacaactgg acatattctc cgacacaatc cagccatcga aaccatcaaa
    14161 gaagaagcaa attttggtgg aaaagaccaa gcctttattc aattagacaa tggacgcagt
    14221 gtctttgtac gaggcaaggt ggaccggatt gaccgtttga aagctaatgg agcgatagga
    14281 gtagtagact acaaatccag tctgactcag ttccagtttc ctcatttctt taatgggctc
    14341 aattctcagt taccaaccta tcttgctgcc ctaaaaagag aaggggagca gaactttttc
    14401 ggcgccatgt acttggaaat ggctgaacct gtccaatctc tgatggcggt aaaaagtctg
    14461 gcaggagcag tggtagaagc cagcaaatct atgaaatacc aagggctctt ctttgaaaaa
    14521 gaaagcagtt atttaggcga attttataac aaaaacaagg ctaatcaact gacagatgag
    14581 gaatttcagc tcctactgga ctacaatgcc tatctttaca agaaagctgc tgagaagatt
    14641 ttagcaggcc ggttcgccat caatccttat actgaaaatg gcagaagcat tgccccatac
    14701 gtccagcaac atcaggctat tacaggcttt gaagccaatt accatctggg ccaagcccgt
    14761 ttcctagaaa agttggacct agctgatggc aagcgtctgg tcggagaaaa actcaagcaa
    14821 gcttggcttg aaaaaataag agaggagttg aatcgatgaa gcttattccc tttttaagtg
    14881 aggaggagat tcaaaaactg caagaagcag aagcaaattc gagcaaggaa cagaagaaaa
    14941 ctgccgagca aatcgaagct atctacactt ctggccagaa tatcctggtc tcagcatcgg
    15001 ctggttctgg aaagaccttt gtcatggcag agcgcattct ggaccaattg gcgcgtggtg
    15061 tcgaaatttc tcaactcttt atctcaacct ttaccgtcaa ggctgcaact gaacttaaag
    15121 aacgtttaga gaaaaaaatc agcaagaaaa tccaagaaac agatgatgtc gatctcaaac
    15181 aacacttggg ttgccagttg gcagacctac ccaacgctgc catcggaacc atggactctt
    15241 tcacacaaaa attccttggc aaacatggtt atctgcttga tattgcacct aatttccgta
    15301 ttttacaaaa ccaaagcgag caacttcttc tcgaaaacga agtctttcat gaggtctttg
    15361 aagcgcatta ccaaggtaaa cagaaagaga gctttagtca tttgctgaaa aactttgctg
    15421 ggcgtggcaa ggacgaacgg ggtctgcgcc agcaagtcta taaaatctat gacttcctcc
    15481 aatccaccag taatcctcaa aagtggctga gtgaatcttt cctcaaaggc tttgagaaag
    15541 ctgattttac cagtgaaaaa gaaaaactga ctgagcaaat caaacaagcc ctctgggatt
    15601 tggaaagctt tttccgttac catctggata acgatgccaa ggagtttgca aaggctgcct
    15661 atttagaaaa tgttcaatta attctggatg aaattggctc cctaaatcag gagttcgata
    15721 gtcaggctta tcaggcagtg cttgcgcgtg ttgtcgccat ctctaaggag aaaaacggtc
    15781 gagctctgac taatgccagc cgtaaggctg atttgaagcc cctggctgat gcctacaacg
    15841 aagagagaaa gacccagttt actaaactag gacaattatc agaccagata accattctcg
    15901 actatcaaga acgttatcat ggagacactt ggaaactagc taaaaccttc caatctttca
    15961 tgagcgattt tgtagaggct tatcgtcaga gaaaacgaca ggaaaatgcc tttgaattcg
    16021 ctgatatcag ccattacacc attgagattt tagaaaattt cccacaagtt cgtgagtctt
    16081 atcaggagcg cttccatgaa gtcatggtcg atgagtatca ggataccaac catattcaag
    16141 aacggatgct ggaattgttg tctaatggcc acaatcgctt tatggtggga gatatcaagc
    16201 aatccatcta tcgtttccgt caggcagacc cgcagatttt caatgagaaa ttccaacgct
    16261 atgcgcaaaa tcctcaagaa ggcaagctca ttctcctcaa ggaaaatttc cgtagtagtt
    16321 cagaagtgct gtcagcaacc aatgatgtct ttgaacgtct catggaccaa gaggtcggcg
    16381 aaatcaacta tgataacatg caccagcttg tttttgccaa taccaaactg actcccaatc
    16441 cagacaacaa ggccgaattt ctcctctacg acaaggacga tacaggtgag gaagaagaga
    16501 gtcaaacaga aacgaaacta acaggcgaaa tgcgcttagt tatcaaggag atccttaaac
    16561 ttcatcagga aaaaggtgtt gcctttaagg aaattgccct tctgacctct agtcgtaatc
    16621 gtaatgacca aattctactt gccctgtctg agtacgggat tcctgtcaaa actgacggag
    16681 agcaaaacaa ttatctccaa tccctagaag tgcaagtcat gctagacact cttcgtgtca
    16741 ttcacaatcc cctgcaagac tacgccttgg ttgcccttat gaagtctcca atgtttggtt
    16801 ttgatgagga tgagctagca cgtttgtccc ttcagaaagc agaggataaa gcccacgaaa
    16861 atctctatga gaaactggtc aatgcacaaa aaaaggcaag tagtcaaaaa ggcttgattc
    16921 acacagctct agctgaaaaa ctaaagcaat tcatggatat cctagcttct tggcgcttgt
    16981 atgccaaacc ccactctctc tatgacttga tttggaagat ttacaacgac cgtttttatt
    17041 atgactatgt tggggctttg ccgaatggtc ctgctaggca ggccaatctc tatgccctag
    17101 cactgcgtgc tgatcaattt gaaaagagca atttcaaagg tttgtcgcgt tttattcgta
    17161 tgattgacca agtcttagaa gcccagcacg atttggcaag cgtggccgtc gcaccgccaa
    17221 aagatgcagt agagctcatg accatccaca agagtaaagg gctggagttt ccttacgtct
    17281 ttatcctcaa tatggatcaa gatttcaaca agcaggactc tatgtcagaa gtcattctca
    17341 gtcgtcagaa tggtcttggt gtcaaatata ttgccaagat ggagacaggg gcagtagaag
    17401 accactatcc taaaaccatc aaactctcca ttcctagtct gacctatagg cagaacgaag
    17461 aggaattaca gctagcaagc tattctgagc agatgcgttt gctgtatgtt gctatgacgc
    17521 gggctgagaa aaagctctat cttgtcggca agggttctcg tgaaaagctg gaagctaagc
    17581 aatacccagc agccaaaaat gggaaactaa atagcaatac tagactgcaa gcacggaatt
    17641 tccaagattg gctttgggct atcagtaaag tgtttactaa ggacaagctc aactttagtt
    17701 atcgttttat tggcgaagat cagttgacca gagaagctat cggagagttg gaaaccaaga
    17761 gtcctctcca agatagctcc caagcagaca atcgtcagtc agataccatc aaagaagctc
    17821 tggaaatgct gaaggaggtg gaagtttata atactcttca ccgcgcagct attgaacttc
    17881 ctagtgttca aaccccaagt caaatcaaga aattctacga accagttatg gatatggaag
    17941 gtgtcgagat tgctggtcaa ggtcagtcag taggcaagaa aatcagcttc gatttgccag
    18001 atttttcaac caaagaaaag gtaactggag ctgagattgg tagtgctact cacgaactca
    18061 tgcagataat tgacctcagc cagcaactaa cccttgctag cctaacagaa acactcaaac
    18121 aagttcaaac tagccaagct gtcagagaca agatcaatct tgataaaatt cttgctttct
    18181 ttgacacagc actcggtcag gaaattcttg ctaataccga ccatctctat cgcgagcaac
    18241 ctttctccat gctcaaacga gaccaaaaga gtcaggaaga ctttgttgtc cgtggtatcc
    18301 ttgatggcta tctgctttac gaaaacaaaa ttgttctgtt cgactacaag acagaccgct
    18361 atgatgaacc aagtcaactc gtagaccgct atcgtggtca gttagctcta tacgaagagg
    18421 ctttatcacg agcctattcg attgaaaata ttgaaaaata cttgatttta ctcggtaaag
    18481 acgaggttca agttgtaaaa gtataactta tactcttcga aaatctcttc aaaccacgtc
    18541 agcttcgcct tgctgtatat atggttactg acttcgtcag ttctatccac aacctcaaaa
    18601 cagtgttttg agctgacttc gtcagttcta tctacaacct caaaacagtg ttttgagctg
    18661 actgcggcta gctttctagt ttgctctttg atttttattg agtattagaa aggagacctc
    18721 atgacacttc cagttagaaa atccctgcac gatgcagttt tacaggcttc gaaagcggat
    18781 acttgggaac aagctaccaa ggaatggaat gaagtttcct tgatttttaa cggtattggc
    18841 cgtagcaatt gtgtctgtgg aaatgccatc aaatacgctt atgaactctt taacggtgtc
    18901 acaggccaac gcctctttcc aattggtagc gactgtgttc gtcattttca tcgattgtcc
    18961 cttgaccagc aattggaaga ggaagaaaaa ctgctcagaa aggttgaaaa tctaaccaga
    19021 aaagctcaga aaaaggaaaa aatcaaggtc aataaaagtg actttgacga gcgacttcta
    19081 aaatggctct gggaaaaagg tgttttcaaa cccaatcgtg gcaatcaatt tgcgcctgag
    19141 agagactacc agcttttcct agaagtcttt cagggaggaa gttggaccaa ggcggaacca
    19201 aagaaaaagg ctcggatgga agaagtcctt gaaaagtgta tcaaaccctt tttacttggg
    19261 aaatcggatg accaactcta ccttgtcaag ctaggcaagg agaaaattga ctacgaacaa
    19321 gaactccgta tccaggcaga gaaagaacgt aagaagaggg ataaaatcgc caagcaatat
    19381 gcagacaatc tggttctagc catgggaccc gcagagcgtg cttatcaaga ttactttggc
    19441 tttacagaga ccctgactca agaagaacgc aagtgggaaa aaattctttt tggtaaaaat
    19501 agagcagaac gggctatcaa ggccaaacaa taccaaaaag agctggaaaa agaccaacga
    19561 attgccagtc aggatccaat tgaaagaaaa cagaagcaga cttggctcct caattcctat
    19621 tttcgtgagc ttcctgaaga aaaagctcga ttttctaggc tcttattaga atatcgaaaa
    19681 aatggtgaag tacccttttc aactgaatac ctgtcagatc atctcatcga ctttttctat
    19741 aaaatgaaag cctttgaatt tgaaatcgca ccagaacaag tccgagattt tctaaaaaaa
    19801 agcctgcagg aagaccatcg ctcatcagca caaggaagct ggatagaagg aattctcctc
    19861 aactgcctca aaccattttt agaacgatta gtgatatgag taacacctac cgtgtaaatt
    19921 tcatggtagg tgttattgta cccccaaata atataaaaca aagtatgaaa gcgcatctca
    19981 attttaagac ttttttgtaa attaagagta taattaaggt atactgcctt ttctatagat
    20041 aatagataat acactaatat aataaaggtc tttgtaacat atataaattt tatttcaagg
    20101 aggaataatg gaaaagtatt ttggtgaaaa acaagagcgt ttttcattta gaaaattatc
    20161 agtaggactt gtatctgcaa cgatttcaag tttatttttt atgtctgtat tagctagttc
    20221 atctgtggat gctcaagaaa ctgcgggagt tcactataaa tatgtggcag attcagagct
    20281 atcatcagaa gaaaagaagc agcttgtcta tgatattccg acatacgtgg agaatgatga
    20341 tgaaacttat tatcttgttt ataagttaaa ttctcaaaat caactggcgg aattaccaaa
    20401 tactggaagc aagaatgaga ggcaagccct agttgctggt gctagcttag ctgctctggg
    20461 aattttaatt tttgctgttt ccaagaaaaa ggttaagaat aaaacggtat tacatttagt
    20521 attggttgca ggaataggaa atggtgtctt agtttcagtc catgctttag aaaatcatct
    20581 tttgctaaat tacaatacgg actatgaatt gacctctgga gaaaaattac ctcttcctaa
    20641 agagatttca ggttacactt atattggata tatcaaagag ggaaaaacga cttctgagtc
    20701 tgaagtaagt aatcaaaaga gttcagttgc cacttctaca aaacaacaaa aggtggatta
    20761 taatgttaca ccaaattttg tagaccatcc atcaacagta caagctattc aggaacaaac
    20821 acctgtttct tcaactaagc cgacagaagt tcaagtagtt gaaaaacctt tctctactga
    20881 attaatcaat ccaagaaaag aagagaaaca atcttcagat tctcaagaac aattagccga
    20941 acataagaat ctagaaacga agaaagagga gaagatttct ccaaaagaaa agactggggt
    21001 aaatacatta aatccacagg atgaagtttt atcaggtcaa ttgaacaaac ctgaactctt
    21061 atatcgtgag gaaactatag agacaaaaat agattttcaa gaagaaattc aagaaaatcc
    21121 tgatttagct gaaggaactg taagagtaaa acaagaaggt aaattaggta agaaagttga
    21181 aatcgtcaga atattctctg taaacaagga agaagtttcg cgagaaattg tttcaacttc
    21241 aacgactgcg cctagtccaa gaatagtcga aaaaggtact aaaaaaactc aagttataaa
    21301 ggaacaacct gagactggtg tagaacataa ggacgtacag tctggagcta ttgttgaacc
    21361 cgcaattcag cctgagttgc ccgaagctgt agtaagtgat aaagg
//
LOCUS       DBEJZV010000034        20609 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.34, whole genome shotgun sequence.
ACCESSION   DBEJZV010000034 DBEJZV010000000
VERSION     DBEJZV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20609
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.34"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..398
                     /locus_tag="ACL3S0_001671"
     CDS             <1..398
                     /locus_tag="ACL3S0_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR1312549.1"
                     /translation="HAMKSQAIVTSQGRIVSLDITVNYCHDMKLFKMSRRNIGQAGKI
                     LADSGYQGLMKIYPQAQTPRKSSKLKPLIAEDKAYNHALSKERSKVENIFAKVKTFKM
                     FSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            complement(387..1034)
                     /locus_tag="ACL3S0_001672"
     CDS             complement(387..1034)
                     /locus_tag="ACL3S0_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGR1312550.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(1143..1661)
                     /locus_tag="ACL3S0_001673"
     CDS             complement(1143..1661)
                     /locus_tag="ACL3S0_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGR1312551.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1698..1826)
                     /locus_tag="ACL3S0_001674"
                     /pseudo
     CDS             complement(1698..1826)
                     /locus_tag="ACL3S0_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(1888..2757)
                     /gene="rsmI"
                     /locus_tag="ACL3S0_001675"
     CDS             complement(1888..2757)
                     /gene="rsmI"
                     /locus_tag="ACL3S0_001675"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGR1312552.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIGEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASKGVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2760..3077)
                     /gene="yabA"
                     /locus_tag="ACL3S0_001676"
     CDS             complement(2760..3077)
                     /gene="yabA"
                     /locus_tag="ACL3S0_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGR1312553.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(3117..4007)
                     /locus_tag="ACL3S0_001677"
     CDS             complement(3117..4007)
                     /locus_tag="ACL3S0_001677"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGR1312554.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLTKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(4004..4642)
                     /gene="tmk"
                     /locus_tag="ACL3S0_001678"
     CDS             complement(4004..4642)
                     /gene="tmk"
                     /locus_tag="ACL3S0_001678"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGR1312555.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4864..5661)
                     /gene="proC"
                     /locus_tag="ACL3S0_001679"
     CDS             complement(4864..5661)
                     /gene="proC"
                     /locus_tag="ACL3S0_001679"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGR1312556.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(5665..6927)
                     /locus_tag="ACL3S0_001680"
     CDS             complement(5665..6927)
                     /locus_tag="ACL3S0_001680"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGR1312557.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6937..8046)
                     /gene="proB"
                     /locus_tag="ACL3S0_001681"
     CDS             complement(6937..8046)
                     /gene="proB"
                     /locus_tag="ACL3S0_001681"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGR1312558.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(8147..10030)
                     /gene="cbpE"
                     /locus_tag="ACL3S0_001682"
                     /gene_synonym="pce"
     CDS             complement(8147..10030)
                     /gene="cbpE"
                     /locus_tag="ACL3S0_001682"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGR1312559.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWRQGINTTYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(10033..10920)
                     /locus_tag="ACL3S0_001683"
     CDS             complement(10033..10920)
                     /locus_tag="ACL3S0_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR1312560.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10910..11371)
                     /gene="lspA"
                     /locus_tag="ACL3S0_001684"
     CDS             complement(10910..11371)
                     /gene="lspA"
                     /locus_tag="ACL3S0_001684"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGR1312561.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(11368..12276)
                     /locus_tag="ACL3S0_001685"
     CDS             complement(11368..12276)
                     /locus_tag="ACL3S0_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR1312562.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKDELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            12305..12466
                     /locus_tag="ACL3S0_001686"
     CDS             12305..12466
                     /locus_tag="ACL3S0_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR1312563.1"
                     /translation="MIPYFRSFPKRKKEHPILLNYLHYLPFSSQPYFQNQFKKITGYT
                     PLQYRKEKR"
     gene            complement(12518..13189)
                     /locus_tag="ACL3S0_001687"
     CDS             complement(12518..13189)
                     /locus_tag="ACL3S0_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR1312564.1"
                     /translation="MKKRAIQILLVLSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVIMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(13243..13464)
                     /locus_tag="ACL3S0_001688"
     CDS             complement(13243..13464)
                     /locus_tag="ACL3S0_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGR1312565.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLL
                     VHGFCPRGTDDLGYIGGGNHLCKGSAARF"
     gene            13736..14545
                     /locus_tag="ACL3S0_001689"
     CDS             13736..14545
                     /locus_tag="ACL3S0_001689"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR1312566.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14726..15601)
                     /gene="aguB"
                     /locus_tag="ACL3S0_001690"
     CDS             complement(14726..15601)
                     /gene="aguB"
                     /locus_tag="ACL3S0_001690"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGR1312567.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15611..16696)
                     /gene="aguA"
                     /locus_tag="ACL3S0_001691"
     CDS             complement(15611..16696)
                     /gene="aguA"
                     /locus_tag="ACL3S0_001691"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGR1312568.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16693..17820)
                     /gene="nspC"
                     /locus_tag="ACL3S0_001692"
     CDS             complement(16693..17820)
                     /gene="nspC"
                     /locus_tag="ACL3S0_001692"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGR1312569.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGSRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKEVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17820..19079)
                     /locus_tag="ACL3S0_001693"
     CDS             complement(17820..19079)
                     /locus_tag="ACL3S0_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGR1312570.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(19076..19936)
                     /gene="speE"
                     /locus_tag="ACL3S0_001694"
     CDS             complement(19076..19936)
                     /gene="speE"
                     /locus_tag="ACL3S0_001694"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGR1312571.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            20192..20609
                     /locus_tag="ACL3S0_001695"
                     /pseudo
     CDS             20192..20609
                     /locus_tag="ACL3S0_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5996 a         4722 c         3680 g         6211 t
ORIGIN      
        1 gccacgctat gaagtctcag gcgattgtca caagtcaagg gagaattgtt tctttggata
       61 tcactgtgaa ctattgtcat gatatgaagt tgttcaaaat gagtcgcaga aatatcggac
      121 aagctggtaa aatcttggct gacagtggtt atcaagggct catgaagata tatcctcaag
      181 cacaaactcc acgtaaatcc agcaaactca agccgctaat agctgaagat aaagcctata
      241 accatgcgct atctaaggag agaagcaagg ttgagaacat ctttgccaaa gtaaaaacgt
      301 ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt
      361 tgagtgctgg tattatcaat catgaactag gattctagtt ttgcaggaag tctaatgtaa
      421 ttctcaagct gtgagttcat tatgatttgt aaatccgata tatcttcagc agctaaaaac
      481 acattttgaa atgttccaag tccgttttca ccaaaactat attctctctt actatactta
      541 ctcttattat tctctatata gttagagtca aggttcttaa cctcttgaag ttcattttct
      601 ttacttctga ggttaaaatc ttttacttct gaagttaagt tttttgactt ctgtaagtca
      661 ttttctttta cctgaaatat actcataaag tctttaacat aaatgatatt cggcttacca
      721 agtccaagcc ttactctttc gatcagtcct attccttttt ttacatcaag ctcatctaat
      781 gtttttatgg cagttggctt tgagatattt cttcttttca taatttcttc gacagtaaaa
      841 tagataaata ctctgccttc cttgtctatc cagttattct taaatgacat tcctgtctgt
      901 ttaagaagta tggaataaag gataattgct tctgctgata agccccgaaa ttcttctcta
      961 tcaactaata tctccggtac ttttaagaag ttaaatcttt ccgcttctct gttataaaaa
     1021 tattcaaagt ccatgcaaga tcacctccct tcttaaaaat ttgcaaagaa aaagacgata
     1081 gtttttcttc tatcgccttt ggtaaccatt tttatgaaat tttttaaagt taaaaatata
     1141 atttataata ctatcttctt ccattttctg attttagttc tgaaagttcc aaaaggtgca
     1201 accgtattta catgaataaa cttatacact tcccaagtcg ctgttttagt cgcttcatca
     1261 gcccactttc tcatatgcgg ttcaaataat tcttcctcac tcaacgaatc aatcattgca
     1321 gagatagaat taatattttc atttaatttt gctttcaact cttgcagaga taaatgagcg
     1381 taggtatctg tgaaccactg atataactca ccaagttgat tccatttaaa tttatccgat
     1441 ggtgttttta cttgaagccc ctttctttca tcttcttccc atttaagaac caagttggtc
     1501 caaccaacct gataagcaag gttttctgct ggagttctgt caacttcatc agctctctta
     1561 tcttttaaat tttctggaat attatcaaat tctaaaatat atttctcaaa tgttttctct
     1621 atctcagctt ttagttcttc tttattttcg tatgttcgca aaaaatcacc ttctttctga
     1681 tttatcaatc ctttgattta aaatgacctt atttttctat ttataccttc taagaacgct
     1741 ataactgctg ctccaaccat cggtattccg tatgggctta ataaaaaact taataccaaa
     1801 gcttctatac caagtgatac atctttatat tatcatcact aattaagtta aacagaaaca
     1861 gacagaatta ttacatcctg tctcccttta ttgtttttct tcccagtcgt ggtaggcagc
     1921 gtagagttga ctcttattcc actggtaaat cttagctact tccttaatag cttgattttt
     1981 cttcatacct tgctggatac gagcttggat ttctaagaac aagtcttcct cgtctttttc
     2041 ttccacacct ttgctggcac cttcaacaat cagaagacat tcacccttga gagacgtttc
     2101 agagatgctt tccagcaatt cagaaattgt acctctttgg tattcttcat agattttggt
     2161 caattccctg accaagacaa cggagcggtc accgtagact tctaacatat tttccaacgt
     2221 gtctgctaca cgatgaggtg attcataaaa aatctgtgtt tcaggataat cttttttcga
     2281 gtcaaaaaat tgcttctgct ggcctgattt tctcggtaaa aagccgtaaa agatatgtgg
     2341 ctgcggcgct aaaccactgg caatcaaggc agaaattcct gcagaggcac ctggaactgt
     2401 aacaactgca atttcttccc caatagctgc cttaactaaa tcatgaccag ggtctgaaat
     2461 gctaggcaaa ccggcatcag agacctgagc aatactttgc cctgctttca agaaaccaat
     2521 caaatcagga attttttcct tggcattgtg ctcatgaaaa ctgatctgct tggtggaaat
     2581 gtcaaaatgc ttgagcaaaa gccctgtatt gcgcgtatcc tcagcagcaa tccaatctac
     2641 ttctttcaag gtctggatag cacgaaaagt catatcatct agattgccaa tcggcgttgc
     2701 cactagatac agcttgccat agggagactg ccccttaaaa cttttttgaa tttgcatgcc
     2761 tactccctgt ataacaactc atcacagaac atacattctt cgtcctgctc tcgacgttgt
     2821 ccataaaaat cattacatac gtgaaatcca tcacggtaaa tacgacggac actttcgcga
     2881 acatgcttgg ccttgacggg agcgtctgct tccacctcac ccaagcgttc tcgcaactta
     2941 ctattttcca agcgaagagc tgtattttct tctaccaagc tcttgagatt tttcttgatg
     3001 gcttccacat cggctaaggt taccaataat tgttgggaaa aatcatccag cgcgtcaaat
     3061 aattcttttt tgtccataaa acagcccttt cctttcttta tcattcattt ttgagtttat
     3121 atttctttca agaccagata ttccatggca ttttgaaagc tgacattagc ttgccacatt
     3181 tttctagctt ctagtaaatc ttgtagaatc actcttactc ttacctgcaa gaggtcctgc
     3241 ccacagagaa cttcaagaat ccgtaaaacc tgatcctgtt tttccttatc atctgccaag
     3301 ttggctaatt tggcaacctg tagataactt tcttttttct tagctactaa ccaagtcagc
     3361 aggcgttcac tttcatcgac caaggtccaa aaacttgcct gattagccaa cttttctgct
     3421 tcagctcgcg attgactaaa cttagttaaa agagtcgctt ttttcttaac aagtcccatt
     3481 tgttctaaga gtaagatgag tttttcttct tgctttttaa agtggaagat ctgagtccga
     3541 cttcggattg tcggtaacat cttttcctca tcgctagtca agaagaaaat ataaacttca
     3601 ctctggggtt cttcgatgac cttgagcaga gaattggctg cgttgggatg cattttatcc
     3661 gcttgctcga tgataaagac ctgttgctgg ctttcaatcc ctgcttgaga aaactgtccc
     3721 accaattccc gaatgcgttc tgtcttgatg acctgattga ctggcttaat caaggtgaca
     3781 tctggaaact cttcctgttc aatcagcttg caacttcggc atttctcaca tggtaagacg
     3841 ccaactttat ccgtacaaaa gaggctctta gctaaaaatt gcgccatttc caagcttcca
     3901 aagaaacctg aaaagagata ggcgtgattg agctggtctt gttctaagat acggacaaaa
     3961 cggtcaaact gagctggttg ccaagccttt agttgatctt gtttcatttg gccaagccca
     4021 ttccgtcaaa caagacagcc ttggtagttt ccacaacttg ctccaaaggg agactagcat
     4081 caatcttgac aatgcgattt ccttcttttt ccaggagaga aaggtagcct tgacgaactt
     4141 ttttatgcaa gtccaaccct tccaaatcca aacgattaac ctcgcggtca ctattagcag
     4201 caatacgagc cagcccttct tccacctcga tgtcaaaata gagtgtcaaa tcgggtttga
     4261 ggccatctgt cgcaaactga ttgagccagt caatggcttc aatatctaag ccacgaccaa
     4321 atccctgata ggcaacagaa ctatcgataa aacgatccat gatgaccaac ttgccagctt
     4381 caagggctgg aagaactttt tccaccaaat gctgtctgcg actggcaata tagagaagta
     4441 gctctgtttt agcatccatc tgagtatgac ttggatccaa aatcacttcc cgaatcttct
     4501 ccccaatcaa gactccgcca ggttcacggg tcgtcagcac ctttactcct ttttcctcta
     4561 aaattggtag cagagcctct aaaacactgg tcttgcctgc tccctctggt ccctcaagag
     4621 agactaaaaa tccttttgac atgtctaact catttctttt ttactacttc tattctatca
     4681 aaaaaatagg ggtttgtgac aatctttttg tgtcttctca tttcatactc aatgaaaatc
     4741 aaagagcaaa ctaggaagct agccgcaggc tgtacttgag tacggcaagg tgaagctgac
     4801 gcagtttgaa tttgattttc gaagagtatc aaccaccata aaagaggcag ataaaactac
     4861 ctcttattta cctagttctt gtgttcgttt gtaggcttga tgaactgcat ccatgactgt
     4921 tcctcggaaa gcatgcgctt ctaggcttgc tacaccagcg atagtcgaac cgcctgggct
     4981 acagacttgg tctttcaata ctccaggatg ttgctggctt tctaggacca attgcccagc
     5041 tcctaccaca gtttgggctg ccattttcaa ggctgtttct cgtggtaatc ccgtctgaac
     5101 acctgcatct gccaaggcct caataaagag atagacaaag gctggtccac aacctgcaag
     5161 acctgtcgct gcattgatta agctttctcc taattcaacc aagagaccag ccttggctaa
     5221 aagctgacaa aagagctcac tgtcctcagc cctgcaatta ggagacaagg cataactaat
     5281 cactccttgc ccgatagaag caggggtatt aggcatcata cgaataattc ggtgttggct
     5341 tgggataaga cttgctagtt tttctaaggt caatccagct gccatcgaaa tcaaaagaag
     5401 actttctctt ttttcaagga tggtctggta ttgagaaagc agttcagaaa actgagcagg
     5461 cttaacacct agaaaaatca catctgcttc ttcgaatatt tcttcattgt tagaagtctg
     5521 accaccgaag ttagcgatga aagcatccac cttgacttga ctacgattgg caaggagaat
     5581 ctcatctgac ggtctagcct gcaagacaga cttggctaaa ctagcaccca tattccccaa
     5641 accgataaat ccaatcttca tcccttactc ccttatctgt ccatcaccag tgaccacata
     5701 cttgtagcta gtcaattcct tcaagcccat gggaccacgc gcgtgcaatt tctgagtaga
     5761 aatccccatt tcacaaccaa gaccaaattg tcctccatct gtgaaacgag ttgaggcatt
     5821 aacatacacc gctgcagagt ccacttgatc tgtaaagtat gctgcagctt cagcattttc
     5881 cgtcacaata gcatccgaat gatgggtgct gtgggattca atgtgcgcaa ccgcttcttc
     5941 taaactgctc acaaccttaa cagcaaggac atagtctaaa aactcggtgt caaagtcttg
     6001 ggtctcagct gcttgacctg aaacaaactg gcttgctttg ctatccaagc ggaattgaat
     6061 tggttccagt ccagcttcct tacgctctgc aaccagcatt tgatccaagc gaggaaggat
     6121 gcttgctgcc ttgttttcat gaaccagcag aacctccatg gcattacaaa cagaaggacg
     6181 actggtttta gcattgttga tgatagacag cgccttgtct tcgtctgcat ccttatccac
     6241 atagacatgg acaatcccag tccctgtctc gataacaggt acaatcgcat tctcaaccac
     6301 tgcattgatc aagccagctc ctccacgagg aatgagaagg tctagatagc ccttggcctt
     6361 catcatagca taactacttt cacggctagt atcctccacc agttgaatca catttggatg
     6421 aatagtagtc gtctccaagc ccttcttcaa ggctgtgaca atggcatggg ttgtttgata
     6481 ggcatcctta ccactacgaa gaacaaccgc atttccactc ttaagagtca aagcagccgc
     6541 atcagacgtc acatttggac ggctttcata gataataccg atgacaccca tagctacacg
     6601 tttttttgtg ataaccaaac cattttcaag ctgacttgtt tctaaaactt caccgattgg
     6661 atctggtaag gcaaccactt cacgaattcc tcttgccatc gcttctatac gatctgcatc
     6721 caaataaaga cgatccaaca tcacatctga gattttcccc ttagccgctg ccatatcgag
     6781 ggcattagcc gctaaaattt cctcagtagc agccactaag tgatcagcca tggctagcaa
     6841 ggcttggttt ttcacttctt cactagctgt gttaatcgat tttttaacag cctgtacctg
     6901 ttcaaattgt tcttgtctac tcaccatagt ttacctctaa aattctgtaa aaagtagttg
     6961 gatttcagga gtaatggaaa tccagtcgtc acggtaaatc aagacaccct tggctttttg
     7021 agaacgcaac atatcctcca aagcagatgc tccaaattgc acgcgtcctt ttccaagtga
     7081 ttttccactt tccttatcaa atactgtcac gatatcaccg taagaaaaga ctccttctgc
     7141 ttcaacgata ccagataaga gaagactctt tccatgttga gagagagctt ccgcagcccc
     7201 tttatcaacc caaatagaac cttgactctg agcatagaag gcaagccatt gtttctgggt
     7261 acgaagcccc ttctcttgag caacaaagta agaaccatcc tcggtctcct ctgccgcctc
     7321 aatcatggaa tctgatttca aggatgagca gatataaaca ggaactcctg attccgtcgc
     7381 gatagttgca gccttgattt tggttaacat acccccagtt ccgtttgacg aaccagctcc
     7441 accagccata tcaataatct cacgattgat ggtctcgatt ctctccaagc gtttggctct
     7501 tggatctgaa ttaggatttc cagtatagag accgtccaca tctgtcaaga aaactaaaag
     7561 gtctgcttgg accatcgccg ctacttgagc acttagagtg tcattgtccc caaccttgag
     7621 ctcatcaata acgacactat cattctcatt gatgatagga attgccccac ggttgagcaa
     7681 aaccgacaaa gcctgatggg catttttata acgacgctta tccacaaagt catcttgggt
     7741 cagcaagatt tgtgcagaaa cgatttgacg caagagaaga ttggttgtat attcttccaa
     7801 caaaagcccc tgccctaccg ctgctgaagc ctgtttatca gcaattttag tcggacgctt
     7861 tttaaatcct aaggctccaa aaccagccgc aatggcacct gaagacacca aaatcaactc
     7921 atgaccagcc tcgtgcagca tagccaactg ctgggtaata tcctttacct tactacgtga
     7981 taaacttcca tcctcatttg tcagagaaga agtacccacc ttaaagacaa tccgtttgta
     8041 tttcatagtc tcactccgat tattcatatt tatccattat aacatgaata acaggaaata
     8101 gaaaagagtt gataggaaaa agaaggccct aaaaccttct tttctactac tgttctgatt
     8161 ccgatttgtt tacactcgtt tcagagcttt gtgaagttga ggatgtcaaa tcttgactag
     8221 ttgaagaatt tgtaacactt tcatgttgac tcgtttcttt attttcaaga tcctttttca
     8281 ctacttcttt ggattctttt atttctgaat gacttgtagt tttaattgta gcagatttct
     8341 cgatcggaac atccactaac caggcaccac ttgaatccac agtatagcct tctggtgtct
     8401 taccattcac aagtaattga ccattttctt tcaagaagta ccatttatcc ttgtctttaa
     8461 tccaacctat agctcgtgaa ccatctgtct tgtagaaata ccaatcattt gcctttttaa
     8521 gccagccttg cttcatagct cctgattctt ctagatagta atgatgtcca gcaacttcta
     8581 tctcacctgt cttcatgata ccagtagaat ccatatagta ccaggcttct ttatctttta
     8641 cccagcccgt tttcatttcc cctgatggag caaagtaata ccattgcccc ttatattgaa
     8701 gccaacctgt cttcatagag ccatcaacat ccaaataata ccactgctct ttatcttgaa
     8761 tccaaccaat ttccatctgg ttttctttgt taaaataata ccagattcca gcgattttct
     8821 tccaattttt agcagcaaca ccagagtctg tcaaatagaa ccaacgattg ttccattttt
     8881 tccattgatt ctgtaataag atacccgttt ggttaaagta ataccattca cccttaattt
     8941 cattccaacc aacagcatat tctcctgtag aatcaggcgc ttgataccac cagtttccat
     9001 atgaactctt atgccaacca gcttgaaaac ttggaatcgg cttgtaggaa gttgaaatgt
     9061 ttactaaacc gtcttgtcga atatcaaaaa ctgttgcatc atagtctttg ctggctgcgt
     9121 tgattctctc aattcctcgt tctttgagcc aattaacata ctcactatca acaccatttt
     9181 tccaaggtag actatccgaa gtttgaacaa tcaaactcgg actcaaattt ttaatgaaat
     9241 ccttggtatt tgatttgttg gtatcatggt gatgattaaa cttcatcaaa tcaacttttc
     9301 caatgagagg accatacttg tcttctgctc catgaacatt atctaaatcg cccccaaggt
     9361 aaattttctt gccattgact ttcaccacgc taatcaagga attggaattg tcatcccaaa
     9421 ttttctttaa ttcacccgat gaatcagttt cattttcata attatagagc tgaatatcca
     9481 tgtccccaaa ctgaaaatga gcatcccctt gtgtgatatt ttgaataact gaaacacctt
     9541 tttctgcagc agtctgtaaa accttatcat agccatacag attatcccat agacgttcag
     9601 aattagtaat acgactatca ctatatttct taagatagac tcggtcaact ggataggtag
     9661 acagtaattc atcaacattt ccaatatgat cactgtgggt atgggtcacc aaaataaaat
     9721 caagtttttg gacacccaat tccttcaaac gacgaaagac acggtctgtc agaacatgct
     9781 tataagtggt attaataccc tgtctccatg gatagcgaga atcacttcca tctgggaaat
     9841 cataatcttc tcctgtatcc accatggcaa aatgtccatt gctttcaaga ataatcgcat
     9901 cactgccacc ttcttgaaca ttgataaagt ggattttatt tcctgaactt tcttgagcct
     9961 gaacattccc ataccatgac aaacctaaaa aagcgcctac aagtgctaaa ctagttaatt
    10021 tctttttcat tcttactttc tcaatctctc caaggtttcc ttaaaaatct ctgggatatc
    10081 tgctttaaat tccaaggtct tacctgttct cggatgagta aaacctaaag tcttggcatg
    10141 aagaaattgt ccatgtcctt tcaaagtctt gcgaggacca tagacctcat caccagcgac
    10201 tggatggccg atataagcca tgtggacacg gatttgatga gtacgccctg tctccagttg
    10261 caactctact aagctataat cgccaaagcg ttccaagacg tgaaaacgcg tcactgcagg
    10321 cttcccttta gcagttacag cctgtttctt acggtctttt tcactccggc caatcggcgc
    10381 ttcaattaca ccacgatcat taggcagatt tccatgaaca atcgcccaat atttgcggag
    10441 agacttttta tccttgagtt cttgggcaag tgctagatgc gcatcatcgt ttttagcaat
    10501 catgagaaga cctgacgtat ccttatcaat acggtgaaca atccctggac gcagaacccc
    10561 attgataccc gacaagtcct taatatgata catgagggca tttactaggg ttccactggt
    10621 atgaccagca ctcgggtgca caaccattcc ctgaggtttg ttaacgacag ccacatcctc
    10681 atcttggtag actatttcta gcggaagatc ctcagccaca tactctaata cctctggttc
    10741 tggcacatgg taagtgacga catcaccctc ttggactgtg tatttagctt tcttgacttg
    10801 accattgacc aagacctggc ctgatttaat ttgttcattc gcgagactac gtgataattc
    10861 tgacaaatct gacaaagcct tatccaaacg cagaccacca gtttcaattt taatttccat
    10921 ttatttcctc ttttagcatt gcaatcaata aaataatcac tccaaccgtc agatagctat
    10981 ctgccacatt gaaaattgca aagttgataa agtcaaggtg gaacatatcc acaacaaagc
    11041 cctgactgac cctgtcaata aagtttccaa gaccacccgc gattattaga gtcaaaccca
    11101 agaccatcca gaatgagtcc tccatgtgtt tatgtaaata ccaaatggca cctatcacga
    11161 caaccagagt aatgacagcg aataacaact gctgatcttg taagatagaa aaggctgcac
    11221 ctcgattttg caggtaggtc aagctaacga aattggggat ccaggagcgc acttcaccca
    11281 gtggaatctg ctggacgata taggatttga ccaactgatc cagcccaatt aaaagcagta
    11341 caatgactgc cactattgct ctttttttca tgatttcctc ttttgatcaa aatattcttg
    11401 catgacttct acgaagagag tcccagcttg actaagctcc acttcttcac gtttaacata
    11461 gaccatgcgg ttatctaggt tatccttgag acgaataact gtaatgccat taacactgtc
    11521 actatctaaa aatccagaac ctgtcgcata ggcgtccgtc cgctccaaaa taccattcaa
    11581 ggtggcacgg tctgtcacat taaacatctg tgagctagcg ctggtatcga caaagttctc
    11641 tgaataataa aggtactcgt ctttctcttg agtgaaacga accgttggta aatccgctaa
    11701 atcctccatg actaattcat ctttctgggc taaaggatga ccctcacgga gataaatatg
    11761 ggtatggaaa ggaatcaatt cgatgacctc cagacctaat ttttcaaccc gttgcataat
    11821 ccccttttta ttttgattgt tgaggtagat aatcccaatc tcactatgcc cttgcgccac
    11881 ttcatctaat atttgaacag tagttgattc aaaaatacgg aagttcttat agtcaggata
    11941 gcgctctgaa aaggccgtaa tagttggtgg taagaagtca tagtgctggc tagcaacgga
    12001 aaattcatct ttttcttctt caggattggc atactgattt tgaaaaatat caaatccttt
    12061 aaccaattct tgcgcttttt cataaaattc catcccacga cgggtcaaga aagtccctga
    12121 gctggtccga cggaaaatct taaaacccaa ctctttttcc aaatcccgaa cagaaataga
    12181 cagactcggc tgactaacat acatcttttc agcagcttca cgaaaagtac cactattggc
    12241 aatagccaca acatagcgta attgttgaat gttcatcttc tacccctaac ttctttatct
    12301 tttcattata ccatatttta gaagttttcc aaaaaggaaa aaagaacatc ctattcttct
    12361 taactatctt cactatctgc ctttctcaag ccaaccttat tttcaaaatc aattcaaaaa
    12421 aataactggc tacacaccac tacaatatcg aaaagaaaaa cgttgactat ttgtgaaaaa
    12481 agaaaatgcc ggaaagttcc gacattattt tagtaagcta acttcctgaa aataggagca
    12541 accacacatc ccagaaggca gtgatattaa tgagaatatg aactagtatt ggatagtaga
    12601 gatttttagt catgcgatac aatagagcta aaataagacc tccactagca taaatgaaaa
    12661 aagcaagagg agttaaagca aaattgatat gaatataacc gaaaataata gcagaaagca
    12721 aaacatctcc gtaccaaggc gagtttttga aaaaggttgt cataatcaca ccgcgataaa
    12781 tcaattcctc agcaataggg gcgatgaagc aaacgatgag caagaaataa gggaactcct
    12841 gtcgtcccat catttctatc gtttcattca aagaaatttg atttgaaggc ggggatatga
    12901 aatacgaaaa gaggaagtca gacatatatg aaatgatgta gcccagtaaa aggtagatga
    12961 agtacctcag ctgccacttg aaatgaaaaa ttttctttcc tgcaaaaacc agtagataga
    13021 tgaccgctaa gaaaagaact ccactctcca tcaaaagaag aatctgaaaa aattcacgac
    13081 ttgctggtag atagggcttt gcgagataat tgaaaagcct ccaaaaccaa gttgatttgt
    13141 aaaaaattaa ggacaatact agtaaaattt gaatagctcg ttttttcata ttaaatcctc
    13201 tgttttctcc ccttgtttct tcatattcct aataaatttt acttaaaatc tcgcagcact
    13261 tcctttgcaa agatgattac ctcctccaat atatcctaaa tcatcggttc ctctgggaca
    13321 aaatccatga accagcagag ttaatactgg ttctatttcc caatcgtacc taccattagg
    13381 atttttacca tatggatctg ctccaccttg tatcagctct aattcttcat ttgttagatt
    13441 tatatttttt gtcattaaaa tcatgatata tttcctccat tattcttcag attagttgag
    13501 taatctgcta ctcataccta cttacaaaaa aactattata ttaagttggt tttttaattt
    13561 gtctagttgc aacattgaca aacatagtat agcatatctt tgcgaaatat cctcttcaaa
    13621 tcatgaattg tcatcaaaac atcttaaact ataaaatcaa ttagtctcaa gctttctatc
    13681 aatttcttct ccaaaatatg ctataataat agcaaaagat aaagaaggaa gacctatgat
    13741 taaactacta gccttggata tggacggcac cctcctcaat gaagccaagg aaatcccaca
    13801 agctcacatt actgctattc acaaagccat tgaaaaaggt gtcaaactgg ttctctgtac
    13861 gggtcgcccc cttttcggtg tcctccccta ctacaaaaaa ctggagcttg acctccagaa
    13921 cgaatatatt attgttaaca acggttgttc aactcaccag actagcgact ggggcttggt
    13981 tgactggcaa gaactgagtc cagctgacat cgaatacctc tatgaccttg ctgaaaagag
    14041 tgatgttcag ttgacacttt ttgacgagtc acattatttt gttctcggtg gcaaacccaa
    14101 tcaagttatt gaaaatgatg ctaaactagt attttcagac ctgactgaaa tttctcttga
    14161 agaagcgact agtggaaagt tccggatgtt ccaaggtatg tttttaggaa caaaagaaca
    14221 aacagacgat tttgagcagc gttttgctga agagctttgc caacgattca gtggagttcg
    14281 ttcgcagcct gtcatttatg aagcaatgcc gcttggaacg acaaaggcta ctgctctttc
    14341 acgactagct gagattttga agattgattc ctcagagatt atggccatgg gcgatgctaa
    14401 taacgatatc gaaatgctcc agtttgcagg gcttgggatt gcaatgggaa atgccagcga
    14461 ttatgtcaaa tctcttgcgg atgccgttac atcaagcaac gaagaagacg gcgttgcgcg
    14521 tgctattgag aaatatattc tataaaaaag aaaagcaaat agacagaagt tactgctatt
    14581 tgcttttttg ctaatatttt aaaatacgga ctaatcaata gacaagaata gcgaatcata
    14641 aaaatcgatt tactagatgc catagtatct tatagttgct aataagaagt tagtctagca
    14701 gaatgaatct ctcatttctc ccacactaat ctgtaatttg tctatacatt tctggtcttc
    14761 tatctcgaaa caagccccag tttaggcgtt cacttgctcc cttgtctaag tcataagtag
    14821 ctaacagaac agcttcttct tgtctttcag ctcgttctag aatagctcct gtttcatccg
    14881 tcataaagga ggaaccgtag aagtcaagac tggaactctg tccgccattt tcctcactag
    14941 gagtaacctc ctctaaacca taacgattgg ctgcgatgac tggaacaata ttcgctgctg
    15001 cgtgcccttg catagtacgt tgccagtgac cacaactatc tgtatccaaa attggctctg
    15061 aaccgatagc tgtaggataa aagagcaatt cagcaccatt caatgcaaga cagcgcgctg
    15121 tttcagggaa ccattgatcc caacagatac cgataccaat cttagcatag cgagtattcc
    15181 agaccttgaa accagtgtta ccaggcgtga aatagaattt ttcttgataa taatggtcat
    15241 ctggtatatg ggtctttcga taaacgccca gcacttcccc atctgcatca atgacggcaa
    15301 tagagttata caagacatta ccatcttttt catagaaact gattggtaaa acaacttgta
    15361 gttccttagc aatcacctta aaatgctgaa tggcagtatt ttccgctaca gattgggcat
    15421 actggtagta gtcatactga cgttcctgac agaaataggg atgttcaaac aactcgggca
    15481 agagaataat ttgggctcct tgctcagcag cctgacgtac taaacgctct gcggtttgga
    15541 tatttgttgc cacatcctta gcgcattgca tctgaatggt tgcaactctt acatttctca
    15601 tctttttctc ctattctgga atttgttggg tgatacagtg gatattgcca ccacctaaga
    15661 gaatatctct ggctggtatt ccgacaactt tacggtctgg gaaacacttg ctgaggatat
    15721 ctaaggccac ttggtcgttt acatcctcaa actgtggaac caagacagcc ttgttggcga
    15781 tataaaagtt tacgtaggaa gctgctagtc gttcacctgc gtatcgcttt tcttctcctt
    15841 cttcatagat gtagcctggc aaatcttctt ctgtcacaac ttgtcgaact gcagggatag
    15901 gcaatttatg aatggtgaag tgacaacctt ttgcatctgt ttcctgttct aagagttcga
    15961 gatctgcttt tgacatggca tactggggat cattttcgtc atctgtccaa gccaaaacaa
    16021 gctcagcagg accaacaaag gcagcaacat tatcgacgtg ttcattggtt tcatcctgat
    16081 aaataccata aggaagccaa ataacttttt cagcaccaag actttctaat aatgtgtttt
    16141 caatctcctc tttagtcagg ttaggattgc gaccaggact aagcaagcaa ctttcagtta
    16201 cgagaatagt tccttgacca tcgctatgga ttgcgcctcc ttccagtaca aaaggtttag
    16261 catcatagac aggcctttcc aaggcctcag caaaacgact ggctacttgg tcatcctctt
    16321 cataatcttg ataaagacca tcataggtgc ctccccaagc attgaaggcc caatccacgg
    16381 ctaatttctt acctttatca ttgacgagaa tggttgggcc agtatcacgc gcccaggcat
    16441 cattggtggg aatgtctaaa taaacaacct tgtctccaag ataggattgg gcttcagata
    16501 gataggcctg ctccaccaaa agatagactc tttccccttc tgctatggtc tcgatgatct
    16561 gagtaaatgc tcttttagca gcctttcctt gaaaaggcca tgatcctggt cgagtcggcc
    16621 atatcatgag ggtaccatga tggggttcgt actctgctgg catgtgatag cctaattttt
    16681 ttggactgtc catcatgata atctcccttt aaagtcttga tagccaaaag ctttgagtaa
    16741 gctacagtct ccctgttcgt ccatgagata gagacttggc aatccaatac cattaaaggt
    16801 attatttttg acaaaagaat aaatggccat gtcttgaaaa taaagtctgt ctccgatttg
    16861 gactggattt tcaaaactat aatcaccaat cacatcgccc gtcagacagg tattagaaga
    16921 aagtctgtag gtatgggctt tttcctgtgc ctcaaagcca tttctcaaag gtggacgata
    16981 gggcatctca agtacatcag gcatatggca ggtcgcagag gcgtctaaaa ccaagatttc
    17041 cataccgttt tctacaatat ctaatacctc agttgctaaa taacccgcat taagcgcaat
    17101 ggcttcacca ggctcgatat agatttcaag attgtaagtt tttcggatac gcttgatttc
    17161 tgaaatcagc aaatccacat cgtaaccttc tcttgtaata tgatgaccac cacccatatt
    17221 gagccatttt acctcatgta agtagggacc aaactgttct tctacttctt tcaaagttgt
    17281 ttgtaaatca tctgctccct gctcgcaaag ggtatgaaaa tgaagtccgt caaccaaatc
    17341 tagcaaatca ctcggaatct tgtctatagt aactccaaag cgagaacctg gtgcacaagg
    17401 gtcatagagc gcgtgatctc cttgagttga acactgaggg ttgaggcgca aaccaacact
    17461 gacaccagcc tctcgacaac gcgaaccatg cttacgcaac tgtctctctg agttaaagac
    17521 gatatggtct gttatcccaa gcaattcctc catgtcctca tccttgaaag ctggtgcaaa
    17581 aacatggact tcaccaggaa attcttccct tgccaatttg gcctcataga gtccactagc
    17641 tgtcgtacct gatagatact ggctaatcaa gggataagtt ttgtagaggg aatatgcctt
    17701 ctgggcaagc aagaccttgc aaccggcctc ttcttgtaca tattgtagaa tgcggcaatt
    17761 agcttctaac ttggccaagt caataacata ggctggtgtt ggtacttgtt ctaacttcat
    17821 tagtccacca tttgtggatt ttcaaccaca acccatggca aaccatactc attcaaagct
    17881 tccatgaatg gatctggatc taactcctca aggttataca ctccagcttg tttccaagtt
    17941 ccgttcatga ctaattttgt cccaatcatg gctggaactc ctgtcgtata agaaatagct
    18001 tgcgaaccaa cctctgcata gcactcttga tggtcgcaga cattgtagat atagatagtc
    18061 tttttgacac cgtctttgac acctgtaaag atacatccaa tattggtttt acctacagta
    18121 cgtgggccaa ggctagcagg atctggaagc aaggctttca aaaattgaat tggaacaatt
    18181 tcttggccgt taaagttaat ggtatccgta cgaaggagtc caacattttc aagacatttc
    18241 atgtgcgtca agtaagattg accaaaagtc ataaagaaac gaatgcgttt gacacctgga
    18301 atgttcttgg ccaatgattc gatttcttca tggtgaagga gatacatatc tttttgtcca
    18361 acttgaggga aatcatactc acgcttgata gacatagctt cgacttcgac ccatttccca
    18421 tcttcccagt aagaacctgg cgcagaaacc tcacggagat taatttctgg attaaagttg
    18481 gttgcaaatg gataaccgtg gtcaccgcca ttacagtcta aaatgtcgat ataatggatt
    18541 tcatcaaaat agtgtttgag ggcataagct gaaaagacac tagttacacc tgggtcaaaa
    18601 ccagaaccaa gaagagcagt caagcctgct tctttgaatt tctcttgata agcccactgc
    18661 catgagtagt caaagtaggc tgtaaaacca agttccttac aacgtttttc gtagatagca
    18721 cgccactcag ggtcttctgt gtcttctgct tcgtagttgg ctgtatcgat atagtgaaca
    18781 cctgttgcca aacaagcatc cataatggtt aaatcttgat aaggcagagc tacattcaaa
    18841 acagcttctg gtttgtagct ttcaatcaag gtaatgacct cttctacctt gtcagcatca
    18901 agtgctgcag tttcaatttt agtacttgtt ttgccttcta gcttcgcttt caagtcatcg
    18961 cattttgact tggtacggct agcaatcata atctctgtaa atgtttcgct atcttgacaa
    19021 atttttgaaa tagcaacttg ggcaacgccc ccacaaccaa taactagtaa acgactcatt
    19081 tttttccttc ctcttcttct aaaatgtcct caacatactt gggcaacata aaggctccca
    19141 cgtgtaagtt tgcagtgtag tattctgtga aaagctggcg ttttttccaa ccttccttgt
    19201 caaaatcttt gacagggtgg tattttttcg atgcaaatcc aaacaaccaa tagccagctg
    19261 ggctagttgg aatatgggcc tgataaaccc gactgattgg aaaggcttga ttgaccttgc
    19321 ggtgcatgct tcggcaggcc gactcatcct cgtcaaagaa gggactccca tgctggtaaa
    19381 tcatgatgcc gtcttccttc agagctcgat aactattgcc gtagaattcc ttggtaaaga
    19441 gtccttccgt atggccaaat ggatctgtcg catcgttgat gataatatcg taatcatctt
    19501 cgcagtttcg caaaaagcgt agcccatttt ggtagtaaat ggtaacacga ggatcatcta
    19561 gccctgcagc aaagtctggg aaatactcac gacagacctc gaccaacatc tcatccggtt
    19621 ccacgatatc gatttgttcc agttcaggat agagtgttaa tacttgggca acaccgccgt
    19681 caccaccccc aataaccaat actttctttg gatttgggtg gacagccatg ggaacgtgaa
    19741 cggtcatttc attgtagacg aaatcatccg catctgagaa caagacatgg ccatttaaaa
    19801 tcagtatttt cccaaaagct ggcgtatcca agacttcgat atcctgccat tcactttttc
    19861 cagcgtaaag ttgcttggct gttctcagag acaatttgac atctggagta tgaacttcag
    19921 aaaaccataa atccatctat ttctccttat attatattta gcgcagttag ctactgccaa
    19981 agcccaagtg gtatacttgg aataagccac tgtggattag ttcatttcct ccaatcgctt
    20041 gacgatttcc gaaagggtct aaccacagct ttttgtttca attggtaatg agtttgataa
    20101 cgcatagacg ttttatctcg tctaaggtaa caaggcaaaa agttcgtgga taaccaagta
    20161 gacttgaaat actatatctg gaggtactcc catgctttat gtgggcattg atgtcgctaa
    20221 aaataaacac gatgttacag ccttgaatgt ttcaggaaaa ctgttcttaa accactcact
    20281 ttttcaaata ataaagctgg ttttgaactc ttagatctgt ctcttcgaca gctcaaccaa
    20341 gactgtctca tcgctcttga agatactgga cattatgcct ttaatctact gaacttcctg
    20401 catgaacaag gatataaagt ttacacctac aatcctttgc tcatcaagga atttgccaaa
    20461 tcattatcac ttcgcaagac taaaacggat aagaaagacg ctcatggcat cgctcttaaa
    20521 cttctttctg accccaatcg tgaacaattt caacacgata atcggcaagt agacctaaaa
    20581 atactggcta gacatattca tcgtctcaa
//
LOCUS       DBEJZV010000035        20503 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.35, whole genome shotgun sequence.
ACCESSION   DBEJZV010000035 DBEJZV010000000
VERSION     DBEJZV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20503
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.35"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..809)
                     /gene="folK"
                     /locus_tag="ACL3S0_001696"
     CDS             complement(<1..809)
                     /gene="folK"
                     /locus_tag="ACL3S0_001696"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGR1312572.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALK"
     gene            complement(852..1406)
                     /gene="folE"
                     /locus_tag="ACL3S0_001697"
     CDS             complement(852..1406)
                     /gene="folE"
                     /locus_tag="ACL3S0_001697"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGR1312573.1"
                     /translation="MDRQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(1399..2709)
                     /locus_tag="ACL3S0_001698"
     CDS             complement(1399..2709)
                     /locus_tag="ACL3S0_001698"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR1312574.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKARNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENG"
     gene            complement(2711..3685)
                     /gene="folP"
                     /locus_tag="ACL3S0_001699"
     CDS             complement(2711..3685)
                     /gene="folP"
                     /locus_tag="ACL3S0_001699"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGR1312575.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASTIRLADEAENLDLKQYK"
     gene            complement(3780..4487)
                     /locus_tag="ACL3S0_001700"
     CDS             complement(3780..4487)
                     /locus_tag="ACL3S0_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR1312576.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(4540..5958)
                     /locus_tag="ACL3S0_001701"
     CDS             complement(4540..5958)
                     /locus_tag="ACL3S0_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGR1312577.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLVITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAAGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            6148..6960
                     /locus_tag="ACL3S0_001702"
     CDS             6148..6960
                     /locus_tag="ACL3S0_001702"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR1312578.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7299..8318
                     /gene="adhP"
                     /locus_tag="ACL3S0_001703"
     CDS             7299..8318
                     /gene="adhP"
                     /locus_tag="ACL3S0_001703"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGR1312579.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            8552..9541
                     /locus_tag="ACL3S0_001704"
     CDS             8552..9541
                     /locus_tag="ACL3S0_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1312580.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            9569..10372
                     /locus_tag="ACL3S0_001705"
     CDS             9569..10372
                     /locus_tag="ACL3S0_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGR1312581.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            10396..11307
                     /locus_tag="ACL3S0_001706"
     CDS             10396..11307
                     /locus_tag="ACL3S0_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR1312582.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(11363..12697)
                     /gene="pepC"
                     /locus_tag="ACL3S0_001707"
     CDS             complement(11363..12697)
                     /gene="pepC"
                     /locus_tag="ACL3S0_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGR1312583.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(12809..13531)
                     /locus_tag="ACL3S0_001708"
     CDS             complement(12809..13531)
                     /locus_tag="ACL3S0_001708"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR1312584.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEIFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVEIFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILLASIA"
     gene            complement(13754..13984)
                     /locus_tag="ACL3S0_001709"
     CDS             complement(13754..13984)
                     /locus_tag="ACL3S0_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR1312585.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(13994..15235)
                     /locus_tag="ACL3S0_001710"
     CDS             complement(13994..15235)
                     /locus_tag="ACL3S0_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGR1312586.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(15257..15409)
                     /locus_tag="ACL3S0_001711"
     CDS             complement(15257..15409)
                     /locus_tag="ACL3S0_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312587.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(15430..15708)
                     /locus_tag="ACL3S0_001712"
     CDS             complement(15430..15708)
                     /locus_tag="ACL3S0_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGR1312588.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(15701..15964)
                     /locus_tag="ACL3S0_001713"
     CDS             complement(15701..15964)
                     /locus_tag="ACL3S0_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGR1312589.1"
                     /translation="MSKMSMSIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(16066..20457)
                     /locus_tag="ACL3S0_001714"
     CDS             complement(16066..20457)
                     /locus_tag="ACL3S0_001714"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGR1312590.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFETKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFINKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
BASE COUNT         5859 a         4843 c         3965 g         5836 t
ORIGIN      
        1 tttttcaaag catcatacaa gttgcggatc ggttgtttta atatcggatg gataaaatga
       61 ggcgcaattt cctgtaagga ctcaaggaca aaaaggcgtt ccgctatgta aggatgaggc
      121 aatatgaggt cgtctgtata aaggatctgg tcctccacaa agagcaagtc caaatcaatc
      181 aaacgaggtc cccaatgcac ttctctcacc cgtcccagct ctgactcaat ggctaacaag
      241 gtttctaaca agtcttgtgc tggtagccag gtttccacct caaccacttg attggcaaag
      301 ctatcctgct ccactccacc ccaaggctcc gtcgctaaga cactggactc tttgagaata
      361 tggatgccac gagctcgcag tttgtcaatg gcttgcttca agtttgcttg tttatctccc
      421 atattgcttc ctagggcgat aaaggctcgt tgcttgcggc gatgaatggt taccgagcaa
      481 gtatctagtg acaaatgcac cggtgcccaa ggttttttca gttccaactt catttcttgg
      541 acaagaggat aagactcaaa ggtacgttcc accagtttat aggctaccgt ttcaatcaaa
      601 tcttcactcg tttcctgaaa ccaagtcgtc cactgctgac acaattctcc gtaatggaca
      661 gaggctgtta aatccaagtc tgtagctgcc ttggtcatat cataggatag gatggctgaa
      721 acgacaaatt tctgccccaa ttctttctca ctaggaaaaa gaccatgata ggcaaacatt
      781 tccaaatcct taatctgcag ttgatccata atgattcctt tctagaaaaa tccgcttgaa
      841 gcggattctt tttatagccc cattaaacga taagcttggt cacggagatc cttatctgtt
      901 tcaaatagac cacgagctac tgtcgtcaag gttgcagtgc ctggttttct aacaccacgc
      961 atactcatac acatatgttc cgcctcaatg acaacaaagg ctcctttagc acctagatag
     1021 tccatcaagg catcggccac ttcgatattc aaacgttctt gaatttgtgg ttttttcgaa
     1081 taaacttcaa ccgtacgggc tagcttagac aagcctgcca cacgaccatc tggaatgtag
     1141 gcaatgtgcg ctctaccata aaatggcaag aagtggtgtt cacacatggt atggaaaaag
     1201 atatcctttt ctaccaccat attatcgtca ataatttcaa aggattttga caaatgttcc
     1261 tctgctgttt gaccaagacc tgaaaaaatc tcttgataca tacgggctac acgagcaggt
     1321 gtttcctgca agccctcgcg attagcgttc tctcctacag cctcgataat catttttaca
     1381 gctgcttcaa tcttttgtct atccattctc gttcttcctc tccatcagat aggccctcac
     1441 ttggctcaag aaatacaagg aacctgtgac aatcctaact gtttgtttct cttctttttt
     1501 atctgtcaaa ttctgctcta gaaaatcatg ccaatcttgg tagctgagat ttctagcctt
     1561 agctgcctct ttcagcacgc tttcatccgt cgcccgacta tccgcaaaat gtgttagagt
     1621 aagctcggta tctggcatgg ctcccagcaa gtccaacata tcctccaagg ctttggtttt
     1681 gatacaagtg aagaggattt ccttatgata atccgcaaaa cgttcttgca aggttaccaa
     1741 caaggccttg atagcatggg gattatgggc tccatccaaa atcatcaagg gatctcttga
     1801 cacgatttcc aaacgccctg gccaacttgt ttcttccaag gcttgaccaa gaaaatcatt
     1861 gcttgctagc tctcgaccat cttcttgaca aaaagtatca agtaaagcta tggccatccc
     1921 agcattctct atttggtaca aaccaagcag gctagtctgg aagcgacctt gtctgacagc
     1981 acttgtatag tcaaagactt cccctgtcac cacactttct tgatgacgaa cctgataatc
     2041 tgtcccgtag gcaagtctcg gcgcatcttt cccttccgca atgcggtcaa tcacagtcaa
     2101 ggcttctgga gcaatacgcc ctgttaccaa gggcatccct tgtttgataa tacctgcctt
     2161 ctgctctgct atggcctcca aggtgtcacc aagtagggcc acatgatcca agccaatagt
     2221 tgtaattcct gtcaaaatgg gctgacagac attggtacta tccaaaagtc cacccatgcc
     2281 aacttccatg atagccacat ctacttgctc tgaggcaaag tagtcatagg ctagggctgt
     2341 gataatctca aactcggttg tgccctgtaa attggcgacc gcttctccct ccagcaaaga
     2401 ctgatagtct gccatgagag cttctagcct cgcttctgag atcgattccc cattgatgct
     2461 aatctggtct gtgtaatgaa tgagataggg cgaactaaac acgccaactc tcagccctag
     2521 cttttctagc atctttttca aaaaagcaat agtcgagccc ttgccgttag tccctccgat
     2581 atggaggacc ttgagtttga gatggggatt gccacgcaaa gctaacagtt ccaccattcg
     2641 ttccaagcca aaatgcggtt gatccgtccg gtagttagca atccactgat tgttttcaat
     2701 ttctttcatc ttatttatat tgttttaaat ctaaattttc cgcttcatca gccagacgaa
     2761 tggtagaggc aatttcaact gccatcctgt gactagctac gtcatgcacg cgcaccactt
     2821 ctacaccctg tctcgcagca atactagtta catgagccga agccgtgtcc cgatttcgga
     2881 aaccaagctc tgtctcagga ttgacttcaa acccactttc ttcaaggata ttgatgacaa
     2941 atcgcttgcg cgacactccg agaaagattg gatagccctt ctgatgtagt ttatccaggt
     3001 cccgtaaaag gaggagattt tctttcttgg tcagaccaaa gccaattcct ggatccaaca
     3061 ggatattttc tggtgcaata ccagcttctg ccgctctcgc tagtgctcgt tcaaagaaag
     3121 ccaccatcaa gtcttcgatt ggcaatgttt caaagtcagc taactctttt tctgtaaagg
     3181 tttgaccaaa accaaaatga gggaagataa gcgaactagg atgctgaggt cgagccataa
     3241 ctgggttaaa catgatgacc actttcgctc cagctttagc aaccacatgg gccatttttt
     3301 catcacccat gagaccagtg atatcattaa ctagattggc accagcagcc aaagcagcct
     3361 ctgccacctg acttttccaa gtatcgatag aaataaggac atcgctttcc ttgcgaatcg
     3421 ctttgatcac tggaacaaca cgctggattt cctcttctat ctcaacatag ctacttcccg
     3481 gccgagtcga ttctccgccg atatctagca tactggctcc ttctgcgatc aacttccgag
     3541 cctgctggag cgcctgctca agagcaaaaa attgaccacc gtccgaaaag gagtctgggg
     3601 ttacattgat aattccgcaa ataactgtct ttgcatgatt ggctttactt gacatatcgg
     3661 tcactccctc aaggattttc atcatattat ttttctattt taccataaaa agaaaaagat
     3721 ggacacgatt gcattcatct ttccctagta gaaagaggtc ggttcctaca taaaaacttt
     3781 taaacagaaa ttcctaatgt ccgactcata atcaccacaa gagccaacaa acagaaagca
     3841 atcccattaa caatcatgtg aagcaagatc gacatttcca aacgttgggt cttgtaggct
     3901 gtccaagata gaactgtcga catacctcca taaatcaata aagaaggtaa attacttggt
     3961 tgatgcaata aagcaaacac aatcgtaccg actacaaatc ccaagttctc cttgcctcgg
     4021 aaaatctttt taggaacaat cccacgacac aagatttcct cacaaatcgg agcaagcaag
     4081 gctagcaaga agaaactgga aatcaacgaa ctattttgaa ccatatcatt aatctgagac
     4141 tggttagctg ttgtcgtctc atttgacagt tgcaataaaa tggaaccaag tatatttgac
     4201 ccgacaataa ctagataact caagcccaaa cgtgccaaat ctttagctct aaaaaaagaa
     4261 aaattaaaac tagctaactt ggttttacga gctcccataa taaatagagc cagaaccaca
     4321 attgaaaggc cagcaactat cagccctgac tgtagcaggg ctacttcttt taaagtcaaa
     4381 atagaggtaa ccactagggg aacctgatat aaaaggacgg caagtaaaaa gaccaaaatc
     4441 cagcctgcac gattcaacaa ttctttccac atatttttct ctttcatcac ctatctcctt
     4501 tgtattaaaa aaggggggaa atccccctgg gtcattctat tataaggcca tgctgatgta
     4561 gttaaggata aacaaggcat ccaaaatcca aatcatggca tgaacatctt taacttgacc
     4621 tttgacaagc ttagtcaaag tgtaagtcaa gaaaccaact gcaatccctt gagtgataga
     4681 gtagctgaat cccataaaga tagatgtgaa gaaggcagga actgcttcag acatatcatc
     4741 ccaatggata tttttcaagc taccaagcat cataatccca acgataatca agattggagc
     4801 tgtagccgct gttggtacga tcgctagaag tgggctaaag aagcttgaaa tcgcaaaaca
     4861 gatagctaca accaaggctg tcaaaccagt acgtccacct gcaccgatac cagcagcaga
     4921 ctcaacataa gtcgttacgt ttgaagtacc tgcaatggca ccgactgtcg ttccaatcaa
     4981 atcagagtaa agagccttat ccaatttggc tgattggtga ttttcaccat ttgtcgctac
     5041 aataccaact ttttcacctg taccgatcaa ggtaccaatt gtgtcaaaaa tatctgtcaa
     5101 tgagaaggca agaatggcca tcagagtttc aggcaagcga gctgtatctg aaaccaaagc
     5161 tcccaaacct tctgaaccaa gagctgcacc aaagattgtc ttcaaatctt caaaagctgc
     5221 accaacatgg ttattagcaa aatcgatact agacaaatca accaaaccag ctgcaatagc
     5281 aagaacagtt gttgtcaaga tagagagaat aattccccct ttaatccctt tgatgacaaa
     5341 gaagatagta atggcaagtc ctgcaagagc cactaaaaca gctggattat taaagctgac
     5401 caatcctgga actgctgaag agtttgctgc aatcgttgct tgagctttgt cagccccttc
     5461 tcctacaaca gtatagttgc ctggatcaat cgtaaatttc aaaagtccag cattcttaat
     5521 ccctacatag gcaaggaaga caccgatacc agctgaaata gccgagcgaa gggcatttgg
     5581 aatcgattca atgatcattt tacgaacatt tgtcaaggta ataaccaatg aaataatccc
     5641 acagatgaag accatagcta gggcttcttg ccatgaataa ccaagtccaa atacgactgt
     5701 aaaggtaaag aaggcattga gtcccatacc tggtgcttga gcgtatggca agttagcata
     5761 gaaggccatc atcaaggtac cagcaactgc accgataatc gttgcaagaa acacaccctg
     5821 agcaggcatt cctgtttgtg aaagtatttg tgggtttaca aagagaatat agctcattgc
     5881 aaagaaagtt gttaaaccag cgagaacctc tgtacgaacg tctgtaccgt tctcttttag
     5941 tttaaataat ttgtccatca tcaatctcct tttaattttt acgaacaata atagaattat
     6001 atcatttatc attcactttt tcaatgtctt tgtttgattt gtttaagaaa ttaatccaat
     6061 ttcatttttt gtttggaatc tgcttttctg cctgctttct gttataatag aagacatctt
     6121 atctgaaaac acactagaaa ggtccatatg acgaaaaaaa ttattgcagt tgacctagat
     6181 ggaaccctgc tcaactcaga cagtcaaatt tctgacttta ccaaaaaaac catcaaaaaa
     6241 gttgctgaaa aaggccatca ggttattatt acgacaggtc gcccttaccg tatgtcaaaa
     6301 gatttttacc gtgaactggg cttagacact cctatgatta acttcaacgg atcccttact
     6361 catttaccag accaagtttg ggattttgaa aagtgtttga ctgtagacaa aaaatatctg
     6421 ctagatatgg ttcaacgttc agaggacatt caagccgatt ttatcgctgg agaatatcgt
     6481 aaaaaattct acattacaaa tcccaatgaa gaaattgcca atcccaaact atttggtgta
     6541 gaagctttcc agcctgaaga tcaattccag cctgaattgg tgaccaagga ccctaactgt
     6601 atcctcttgc agaccagagc cagtgacaaa tatgccttgg caaaagacat gaacgccttc
     6661 taccagcatc aactttctat caatacctgg ggaggtccgc tcaatatcct tgaatgtacc
     6721 ccaaaaggtg tcaacaaggc ctttgctttg gactacttgc tcaagataat gaatcgtgac
     6781 aaaaaagatt tgattgcctt tggagatgaa cacaatgata ccgaaatgct cgcttttgct
     6841 gggaagggtt atgccatgaa aaatgccaat ccagagctac tcccttatgc agatgagcaa
     6901 atttccctta ccaacgacca agatggggtt gccaaaaccc tacaagactt attcttataa
     6961 cctatactga tactcaatga gaatcaaaga gcaaactagg aagctagccg taggttgctc
     7021 aaagcactgc tttgaggttg tagatgaagc tgacgtggtt tgaagagatt ttcgaagagt
     7081 atgaccagct tgcaagctgg tctttgtgct cttttcacag tctcatcaac cagttaatcg
     7141 attgttctac tttttgtctc caaaaccttg gaaaaggctt tcttttgtga tatacttcac
     7201 atataaatac aagagagctc gtcacactcg actctgttga caaaaaatca atccagtccc
     7261 gttgtccctg ttctcggtca atatcaagga ggatagctat gaaagctgtt gttgtaaatc
     7321 cagaaagcac tggtgttgct attgaagaaa aagtactccg tccacttgaa actggggaag
     7381 cacttgtaga agttgaatac tgtggcgttt gccacaccga cctccacgtt gctcatggtg
     7441 actttggtca agtcccagga cgtgttcttg ggcacgaagg tatcggtatc gttaaagaga
     7501 ttgctccaga tgtgaaaagc cttaaagtcg gtgaccgcgt cagcgttgct tggttctttg
     7561 aaggatgtgg cacttgcgaa tactgtacaa ctggtcgcga aaccctttgc cgtacagtga
     7621 aaaatgctgg ctactcagta gacggtggta tggctgaaca atgtatcgta actgctgact
     7681 atgctgtcaa ggttcctgac ggacttgatc cagcccaagc ttcttctatc acatgtgctg
     7741 gagtaacaac ctataaagct atcaaagaag caaaagttga accaggccaa tgggttgttc
     7801 tttacggtgc tggtggactt ggtaacctcg ctgttcaata cgctaaaaaa gtattcaatg
     7861 ctcatgttat cgcagtcgat atcaacaatg acaaacttgc ccttgcaaaa gaagtaggcg
     7921 ctgacattgt gattaacggc ctcgaagttg aagatgtagc tggactcatc aaagaaaaaa
     7981 ctgatggagg agctcattca gctgtcgtaa ctgctgtgtc taaagttgcc ttcaaccagg
     8041 ctgttgactc cgttcgtgct ggtggtcgcg tcgtcgctgt tggtcttcct tctgaaatga
     8101 tggaactcag catcgttaaa acagtcctcg atggaatcca agtcatcggt tctcttgtcg
     8161 gaactcgtaa agacttagaa gaagccttcc aatttggtgc agaaggtctg gtagccccag
     8221 ttgttcaaaa acgtccagta gaagatgctg ttgccatttt cgacgaaatg gaaaaaggtc
     8281 aaatccaagg acgtatggta ctcgacttca cccactaatc taatagaaac ctattttcaa
     8341 agttggaagc ttcttccaac ttttttatat taaattttta aataagaatt caagattact
     8401 cctcaaaaac tcaacatatc aacatacaaa aataaaaatt ttttaatttt ttatgataaa
     8461 tagttgcttt ttttatgaaa acggtttata cttaaacagt cttaaagttt tcttaaatga
     8521 aaactaaaac aaaaaaggag gaatgacaat aatgagtatc ggaatcatta ttgcgagcca
     8581 cggcgaattt gctgcgggta ttcatcagtc aggatctatg atctttggtg aacaagaaaa
     8641 ggttcaagtt gtgaccttta tgccaaatga aggtcctgat gatctatacg ctaagtttaa
     8701 taacgctgtt gctgcatttg acgcagaaga tgaggttcta gttttggctg acctttggag
     8761 tggttctcca tttaaccaag ctagtcgcgt gatgggagaa aatcctgagc gtaagtttgc
     8821 catcatcaca ggacttaact taccgatgtt gattcaagcc tacacagagc gcctcatgga
     8881 cgctgctgca ggtgtagaaa aagtcgctgc taatatcatt aaagaagcca aggatggcat
     8941 caaagctctt ccagaagagc taaatccagt tgaagaagtt gcaagcgctg cagctgctcc
     9001 agttgcccaa gctgctatcc cagaaggaac tgttatcgga gacggtaaat tgaaaatcaa
     9061 tcttgcccgt cttgacacac gtctacttca cggtcaggtt gcaactgctt ggactccaga
     9121 ttcaaaagca aatcgtatca tcgttgcttc agataacgtg gctaaagacg accttcgtaa
     9181 agaattgatt aaacaagcag ctccaggtaa tgtcaaggct aacgtggttc caattcaaaa
     9241 actgattgag atttcaaaag acccacgttt tggagaaaca catgccctta tcttgtttga
     9301 aacacctcaa gatgcccttc gtgccatcga aggcggcgtg ccaatcaaga ctcttaacgt
     9361 tggttctatg gctcactcaa caggtaaaac attggtcaat accgttttgt ctatggacaa
     9421 agaagatgtt gcgacatttg aaaaaatgcg tgacttgggt gttgaatttg atgtccgtaa
     9481 agtaccaaat gattctaaaa aagatttgtt tgacttgatt aacaaagcca atgtcaaata
     9541 agccattatt tatgaaagga ttttaaacat gtctattatt tctatggttt tagtagtcgt
     9601 tgtagccttc tttgcaggtc ttgaaggcat cctcgaccag ttccaatttc accaaccact
     9661 tgtagcctgt acccttattg ggcttgtaac aggtcacttg gaagcaggga ttatcctcgg
     9721 tggatcgctt caaatgattg cccttggttg gtcaaatatc ggtgctgcta tcgctcctga
     9781 tgctgcactt gcttctgtcg ctgctgccat tatcatggtt cttggtggtg actttaccaa
     9841 gactggtatc ggtgttgccc aagcggttgc tatccctctt gccgtagctg gacttttctt
     9901 gacaatgatt gttcgtacaa tttcagttgg tttggttcat actgcagatg ctgccgctaa
     9961 aaaaggtgac ttcggcgctg tggagcgtgc gcatttcatt gcgctactct tccaaggact
    10021 tcgtatcgcg cttcctgcag ctcttctcct tatggtacca actgaaactg tacaaagtat
    10081 ccttagtgcc atgccagact ggctcaaaga tggtatggct atcggtggtg gtatggtcgt
    10141 tgccgttggt tacgccatgg ttatcaacat gatggcaact cgtgaagtat ggccattctt
    10201 cgctcttggt ttcgttctcg ctgctgtgtc agatattact ctaatcggat tcggtgctat
    10261 cggtgttgct atcgctctta tctaccttca cctttctaaa actggtggaa atggtggcgg
    10321 aggagccgca acttctaacg acccaatcgg cgatatccta gaagactact aagataagaa
    10381 aggactgaaa acatcatgac tgaaaaactt caattaacta aatcagatcg taaaaaagtt
    10441 tggtggcgtt caaccttctt acaagggtct tggaactttg aacggatgca aaacttgggc
    10501 tgggcttata cactcattcc agctatcaaa aaactctata ctaaaaaaga agatcaaatc
    10561 gctgctcttg agcgtcacct tgagttcttc aacactcatc catacgtagc tgctccagtc
    10621 atgggggtta ctcttgcgct tgaagaagaa cgtgctaacg gtgtggaaat cgatgacgct
    10681 gctatccaag gggtcaaaat cggtatgatg ggacctcttg ctggtatcgg tgacccagta
    10741 ttctggttta cagtacgccc aatccttgga tctctcggtg cttcacttgc ccttactggc
    10801 aatatcttgg gtccactcct cttctttgtt gcatggaact tgattcgtat gtcattcttg
    10861 tggtatgttc aagagattgg atacaaggct ggatcagaaa tcactaaaga tatgtctggt
    10921 ggtatccttc aagatatcac taaaggagct tctatccttg ggatgttcat tcttgctgtc
    10981 cttgttcaac gctgggtaaa tattaaattt gctttcgatg tttctaaagt tcaactagat
    11041 gaaaaggctt atatccattg ggataaattg ccagaagggt ctaaaggtat ccaagaagca
    11101 ttcgcacaag taggacaagg attgtctcaa actcctgaaa aagttactac tttccaacaa
    11161 aacttggata tgttgattcc tggattatca ggactactcc ttactttact ttgcatgtac
    11221 ttacttaaga aaaaagtatc tccaatcact attatccttg ccctcttcgc agtgggtatt
    11281 gtggcacatg ttcttcacat catgtaatca agcaactaaa aaggaaccag gttctaaaat
    11341 ctgattcctt ttttctatgc ttttattcag ccaaggctcc cattggatcc catggtgcaa
    11401 gtacaattgg ttctgctcca taggcagctt gttcttctgc tgtcagcaat tccttacgaa
    11461 caacgatttg gtatgtgtat tcgtccatcc aagcgtctga ggcaacaaag taaccatctg
    11521 taccgacctt gtctccccat gagttttcaa ccttccactt ggttgattta ccattttcgt
    11581 ccaagtcaac acctgtcaag accatggcgt gggtcatcaa gctttcgcta tagtccaaac
    11641 gtccagcctt gtcttgagta agtttaatgt ccatgcttga ttcaaagtca taaacatctg
    11701 tcgcaaggat gccagcctta cggttactga gctggccgac atcagaacca aaccaaacag
    11761 tctcacctgc ttgcatttgg gcaatcgcca attctttcaa gcgctccatt ggaacgttga
    11821 tgtaacgaac tgcacggcta ccaaccacat tccccaacat ctcaactgtg taagattttc
    11881 cgtaaggttt atcagcagtt ggagcattga taacagaaac gtagtcttct aaaggaagat
    11941 tgacatattt cttgtaaaac tcttgtggtg tgattccttt ttcacttttg tagttgttat
    12001 ctttatcgcg ataagcaaag tcaaacttgc gtggtggaag tcctaatgac atagcaagaa
    12061 agttaaagat ttcttgcaag aggtcttctt tcttagcttg aacagtcgct tgatctgcac
    12121 cagaaacaag caagtcacgc aagatttgag catcttgacg aagcaattta ttaaggatcg
    12181 catttagctc acgactgctg ctagatgaaa cagactcagg ataaactgac ttaggcacga
    12241 caccgtattt ttcaaagagg gaaacgacca tatcccattg accaccatct tgttgaggtg
    12301 tttgaagtaa gaagctaacc ttgcggctag tcaattcttg gtctgaagtc gcaatgactt
    12361 gctccaagaa ccagtttgat ttctcatact tatcccagaa gaaagtgtgg gcttgtgaca
    12421 actcaaagtt ctccaatttg tattgcgaga tgagtttgtg gcggaaggtg ttgagagccg
    12481 caaacatcca gcaacgacca gacgctttct ggttagtgac cttgtccttg gttaaatcca
    12541 atgagaaaac aggtgtgttg tctacatggc tttggcgacg ttccagagct gcaaaaattc
    12601 cgttgtggct agcagcattt tcaatcgctt ggtattttac atttgcttca tagttggcaa
    12661 atagtttatc agtaaatgat tcttgaatcg cgttcataga ttcctccttt tattctacag
    12721 tctattataa ctcttttcac aaaggaagca actaaaaaac ataaaaggta aggacattct
    12781 ccctcacctt tttcgaatat aaatcaaatt aagcaatact agcaaggaga atttctaatt
    12841 cttccttggt caagcgacgc cattcccctc gttccaggtt ctcatctaat actaaagttc
    12901 ccatagtcaa tcgttgcaag tccaccactt ccttgccaca gtagcccacc atacgcttga
    12961 tctgatgaaa cttcccttct gcaatggtca cacggatttg gctttgattc ttttctgtat
    13021 ctatggatac aagctccagt atagcgggtt gacaggtaaa gtctttgaga ggaataccct
    13081 cagcaaatat ctccacatct tcttgggtca tgattccctt gacttgtgcc agataagtct
    13141 tgtccacatg acgcttgggc gaaagaagaa catgagccag ctgaccatca ttggtcaaga
    13201 gcaaaagacc atgcgtgtca atatccaagc gtcctactgg gaaaatttcc ttactccgcg
    13261 ccaagtcatc caacaagtcc agaacggttc tgtgcttggg atcctcagtc gctgatataa
    13321 ctcctttggg cttgttcatc atgtagtaga caaactcttc atactccaac acttgcccat
    13381 caaagcgaat ctcatctatt ttttcatcaa tctgcaattt agctgatttt tcttttttac
    13441 catttacagt cacgcgccca gccttgagca agtttttgac ctcagtccga cttcccaccg
    13501 cacaggcaac taaaaattta tctaatctca tagaactatt atatcatatc aaaaggaggc
    13561 tggtacaatg accaacctcc ttttcgtttc atactcttca aaaatctctt caaaccgcgt
    13621 caacgtcgcc ttgccgtata tatgttactg acttcgtcag ttctatctgc aacctcaaag
    13681 cagtgctttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat
    13741 cagatttaag aaattaactt cctcgtctcc aaaaaatagc taagacaatc atggcaccta
    13801 aaacagctgg gataatagct gttcctgata aaactggccc ccaagttcca aagagcaagt
    13861 gacctagaaa ggctccgatc caaccgagaa acatttttcc aaaacatccc attcgctctc
    13921 cacgattggt catagcacct gctaaaaatc ccactaggag accaacgaac atacttccta
    13981 acatattatc tccttaattt gcccaattcc cattacggaa aagaggtact cgcgttccat
    14041 cctcacgaat accatcgata tccatttggt tagaaccaat cataaagtct acgtgaacat
    14101 ctgaacggtt aagccctgca gcttcaagct cctcttcgct catctccgct ccatcaacaa
    14161 cgctagtcgc ataggctgca ccgatagcca agtggtttga cgcattttca tcgaaaaggg
    14221 tgttaaagaa ggtaatgcct gactgagaaa ttggacttgg atctggtacc aaggcacatt
    14281 cacccaaggc acgcgcaccc gcattttcaa agacaaggtc tttcataacc tgatcaccct
    14341 tctcagcagt gatatctacg atttgtccat ccttaaaggt caccttaatg ccttcaatga
    14401 tatttccgtt gtagctaagc ggttttgtag aagtgacata accatctgca cgacggaagt
    14461 caggcgctgt gaagacctct tctgtcggca tatttggcaa gaattcttcg ccctgtgcat
    14521 tgacagcacc agctgattcc caaacgtggt tctttggcaa accaagtgtt aaatctgttc
    14581 ctggcgctgt gtagtgaagg gctgaaaatt gctccttatt aagcatatcg gccttgctct
    14641 tgagaatggc tgcatgttcc tcccaagcct taacaggatc tgcttcgtag acacggcaag
    14701 ttttgaaaat ttggtcccaa aggaaatcaa ctgcttcttc gtcgctcgca gcatttggga
    14761 agactttctt agcccactca agtcctgctg cagctgctac agtccagcta actttgttag
    14821 attgagttgc gattcgcatt ggcttcatgg caagtcccat agctttagca gaagctgaaa
    14881 gcttgtcagc gtccactccg ttcaaggcac ctggatcaga tgaacgaact ccaagacggc
    14941 tagccttgtt ctccaagaga tagttcatct cagcaatctt gtattctggc acattgtcca
    15001 aacgctccat cggggcatgg aggaatttct cacggttaat cacatcatct gtccactgaa
    15061 cgatgacctc atgcgcaccc aaggcataag cttctttcac gattagatgt gccaattcac
    15121 gttgctccac atcaatagag agagccaaag tgtgaccagg ttgcacgtta attccgttcg
    15181 caaccaacaa tttcgcatat ttttctagat tttctttaaa atttggtaaa accatcctgt
    15241 tttctctttt ctatttttat ttttctttca aagcagaaaa gattcctgct aaagcaatag
    15301 cacctgacaa gagtgctgtc gatagaagaa ttgtacgatc agcaagttct aattgatatt
    15361 caaatacctt cttagccggc ttatcttccg caaatattct tagtttcatg agaaccccct
    15421 taaaatagat taaaataaat cactgtgact gcctgtcctc agcaaattta aaatcaattc
    15481 cgacttatct actttataaa ccaaaagcca atctggctgg gtatggcatt cacgaactcc
    15541 ttgaaaatgc ttggatgccg tcaatgaatg atcacgatat ctggcaggat gttctttttc
    15601 ttgaaccaga aaattcaaaa cttcttctaa taattctgcc ttcaaaccac gcttcatagc
    15661 caacttaaaa tcttttttaa actgtttatg ataacgaatc ttaagcacgt aagtcctcca
    15721 tcaaatctga gactgattca aaagactggc tcatattacg attttggtct aaatccgtta
    15781 acacttggag caacttccga ttttcgtcta gtctaacatc aaaaggtaat ccctgatatt
    15841 gaattgcctg acgaaggaaa atattaatag ctgttgtcat atccattccc agattactaa
    15901 acacctgttg ggcctgctcc ttaacctcac tatccagacg gatgctcata ctcatctttg
    15961 acatactctc accctctttc catagactat tttaacaaaa aagaaagcta atgtaaatct
    16021 attggatata cgttagcctc ttctaataga ttattaagca attttttaaa acaactcatc
    16081 aaacaaactc aactggttat cctctggcat atttccaaga atacccatct catccatctt
    16141 ttcaaccaag gttgatgaga gtccaccacg cttgcgtagt tctgttttag agaggaattc
    16201 tccctcttca cgcgcccgca ccagttgctt ggcaacgttc tctcccagac catccattgc
    16261 tacaaatggt gggataaggg tatccccgtc gatgaggaac tctgtcgcct gactacggta
    16321 gagatctaat ttgccaaact tgaaacctcg ttcccacatc tcattgacaa tctcaagagt
    16381 tgtatagaga tcgatttcca cattagaggc ttcattgttc ttccgttttt cagagatttc
    16441 ttccattctg cgcttgatgg cctccaagcc cgcacccatg gtcttgatat caaaagcctt
    16501 agcacgaatg gagaagtaag cacagtagta ataaatagga tggtgaacct tgaagtaagc
    16561 tacacgcaag gccatcataa cgtaggctgc cgcatgggcc ttagggaaca tgtacttaat
    16621 tttcccacag gattcgatat accactctgg caccttatta gccttcatgg cttcgatata
    16681 gccatttctc tcctcttctg aaatctttag ccacaaaccc ttacgtaccc gttccataat
    16741 ggtaaaggcc atcttaggtt ccagacccgc atgcatgagg taaaccatga tgtcgtcccg
    16801 acaaccgata acagtcgata ggtccgctat tccttgctta atcagatcct gagcattccc
    16861 caaccaaacg tcagtaccgt gggacagacc agacagctga agcaattccg caaaggttgt
    16921 cggatgggtt tcgtctacca ttccacgtac gaaatttgtt ccaaactctg gaatccccaa
    16981 catacccgta ggcgttccaa tttgttcagg tgttacccct agcacatcag tcccagaaaa
    17041 gagtgccatc acgccttcgt catccatagg aattttatta gggtcaatac cagacaaatc
    17101 ctgaagtttt cgaatcatgg tcggatcatc atgtcccagt acatcgagtt tgaggacgtt
    17161 ctcatcgata tcgtggaagt taaagtgagt ggtctgccat tcagccgtga catcatctgc
    17221 tggatactgg acaggcgtaa aatcgtagac atccatgtag ttcggaataa caacgattcc
    17281 ccccgggtgt tggcctgttg tccgcttgac acccgccgct ccttgagcga ggcgttctac
    17341 ttctgcatca cgataaaact tgccataatc tcgctcgtaa cccttgacaa atccataggc
    17401 agtcttggca gctaccgtac caaccgttcc cgcacggaag gcatattctt caccaaagat
    17461 atcacgcaca tccaagtggg cgctaggctg atcttctccc gagaagttca agtcaatatc
    17521 aggaacctta tccccatcaa aaccaaggaa ggtctcaaac ggaatatcct gtccgttttt
    17581 actgagtttg tgaccacagt ttggacagtc cttatggggc atatcaaatc ctgaaccgta
    17641 cgaaccatct gtgataaact cactgtactg acactgacca cagacatagt gaggagagag
    17701 aggattgacc tccgtaatcc caatcatggt cgcaacgaaa ctagatccga cagacccacg
    17761 agaaccaacc aaataacccc gttcattaga acgttgcacc agcatctgcg atgccagata
    17821 aatcacagca aatccattcc ccagtatgga tgttaattct ttttcaatcc gcaaatcaac
    17881 aatatctggc agcggatttc cataaatctc aaaagctttc ttataggtca actcagcaac
    17941 tgtttcttca gccttgttga tgaaaggcgt atacaagtca cccttaacga cttcaacggg
    18001 ttcaaatatt tctgccaagg cattagtgtt ttcaataacc agtttacgag ccagttcctc
    18061 tcccaaaaag gcaaattcat ccaacatctc attagtcgtt cgaaaatgag cctttggaag
    18121 tggcgctggt tgggcatgtt caccatgacc gatagttcgg ttaatcatcg caccctgtcc
    18181 caaactacgg acgataattt cacgataaat ctcttcttcc ggttcgatat agtgaacatt
    18241 tcccgtagcc agaacaggct tgccaaggcg atctccaacc tctatcaaac tcttgataat
    18301 ggtctggagt tcctccatat ccttgacctg ctctttggca atcaagggcg catagatagc
    18361 cggtggcatg acctcgataa agtcataata cttggccacc tcaaccgccg catccacacc
    18421 ttgagaaacg accacgtcaa aaacttcacc ctctgaacag gctgaaccta aaatcaagcc
    18481 ctctcgatgg gcatctagaa ccgttctcgg aatccgtggc actccttcaa aatacttggt
    18541 attagacaag gaaaccagct taaagatatt ttttagacct acctgattct tgacatagat
    18601 ggtcgcatgc ttgatccgag cttttttgta agaatctgga ctgattagat caatgttgag
    18661 tctagctaaa tcggtcacac catgtttttc tgctacctct ttgataaaga tgaaaagcag
    18721 acgaccagtc gcttccgcat cgtagttggc catgtggtga tgttccaagg ccacaccaaa
    18781 acgcttggtc aaaggcccca aaccatggcg tttatactca ggatagaggt ttctagcaaa
    18841 ctccagcgta tcaataactg gctgactaat ctttggaaga ccatgacgct cataattagc
    18901 attcataaag ccaacgtcaa aggcagcatt gtgggcaact aggaccgtat ccttgcaaaa
    18961 ttcttggaat tcttgcaaaa cttgttctag tggtttggca tttttgacat gatcatctgt
    19021 aattccagtt aactctgtag taaaagctga caagggatgc ccaggattga taaattcatc
    19081 aaattcagca ataacattcc ccttgtacat cttagaggcc gcaacctgaa tcaagtcatt
    19141 atagatagct gaaagtcccg tcgtttccac gtcaaagacc acgtaggttg cttctgataa
    19201 gtccatctcc acttcgttat agacgatagg gacacggtcc tccacgatat tggcttctat
    19261 cccatagatc agctggattc ccgctttctt agccgcctta tagccatgtg gaaaggactg
    19321 gacattccca tggtctgtga tagcaaccgc cttgtgtccc cacttagcag ctgttgcaac
    19381 aatctcttcg acctctggca aagcatccat agtcgacatg ttagtatgag catgaaactc
    19441 aacccgacgc tcaccttctg gcatcaaatc cttccgctca tagtgaacaa cttcctgcag
    19501 atcctgtacg ttcatagtca aatcgcgtgt gaagttattc atctccacat tccctcgaac
    19561 tcggagccaa gaattcttct tgatgaggtc aaacttctgg gcctcttcct cgtttttaac
    19621 ccacttttgc atagaaaaac ttgaagtata gtccgtcatt ttaaagttga ttaaaacacg
    19681 acctgttcta gtcacttttt gctccacatc aaaaacaacc ccttcaaata ccagacgatt
    19741 ttcctctgtc gtcacttcga tcataggagt aatctccgcc ttatccagct tgggtttagc
    19801 tgcagctttt ttcgcttgaa aatcaaagac tggtttctct tccgctggag gaggtgccat
    19861 ctgctccagt tgttccatag cacggagcgc ttcctcattg gcagcttgaa caatctgctc
    19921 attttcagca tgaaaggcct cttcctgctc ttgggtcagg acatcattct tctcgacttg
    19981 acagttaaaa gttggaaaac caaacttttc aagttgtttg gctaaattag gaagatgatt
    20041 cttcttaaaa tgttccttat caatcgcttc agatccttca ataaatagct gattaccctc
    20101 agcacgaact tgcaaatttt gataaaggga cttaaaacct tgactagcac atggaccttc
    20161 agagaaagcc tccctatagt aggactgcaa gagctgattt gaaaattctt gagaccgagc
    20221 cttagtttca aaaacagctt tattgcctgt cttagaaaat tcttcgctca aacctttctt
    20281 taattctaaa aagatttcaa tcggtaaaat attagaaaat acgaaatgaa actcccatac
    20341 cttactaatt ttatgaacca caactcgctc aatattggcc tgtgctaaag caggagcctg
    20401 tctcatttca gcaggcatcc ccaattgatt catcaaaatt tcaaaactat ttgacattca
    20461 ttttcctcac attattcttc tactatttta ccatatttag agg
//
LOCUS       DBEJZV010000036        19829 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.36, whole genome shotgun sequence.
ACCESSION   DBEJZV010000036 DBEJZV010000000
VERSION     DBEJZV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19829
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.36"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(8..1354)
                     /gene="glnA"
                     /locus_tag="ACL3S0_001715"
     CDS             complement(8..1354)
                     /gene="glnA"
                     /locus_tag="ACL3S0_001715"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGR1312591.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(1391..1747)
                     /gene="glnR"
                     /locus_tag="ACL3S0_001716"
     CDS             complement(1391..1747)
                     /gene="glnR"
                     /locus_tag="ACL3S0_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGR1312592.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(1824..2351)
                     /locus_tag="ACL3S0_001717"
     CDS             complement(1824..2351)
                     /locus_tag="ACL3S0_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR1312593.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(2487..3683)
                     /gene="pgk"
                     /locus_tag="ACL3S0_001718"
     CDS             complement(2487..3683)
                     /gene="pgk"
                     /locus_tag="ACL3S0_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGR1312594.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINVLEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(3773..8713)
                     /locus_tag="ACL3S0_001719"
     CDS             complement(3773..8713)
                     /locus_tag="ACL3S0_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGR1312595.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     ASEAVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTVQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTSDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFSDVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGKDEASPKTILGIEVSQEP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGH
                     EVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNT
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            9002..10633
                     /locus_tag="ACL3S0_001720"
     CDS             9002..10633
                     /locus_tag="ACL3S0_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGR1312596.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGDLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFETTL
                     NLAPEMTIAFAHGTFNITNTIIQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(11192..12799)
                     /locus_tag="ACL3S0_001721"
     CDS             complement(11192..12799)
                     /locus_tag="ACL3S0_001721"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGR1312597.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYIAFVTAAVENSN"
     gene            complement(13189..13776)
                     /gene="rpoE"
                     /locus_tag="ACL3S0_001722"
     CDS             complement(13189..13776)
                     /gene="rpoE"
                     /locus_tag="ACL3S0_001722"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGR1312598.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(13904..14352)
                     /locus_tag="ACL3S0_001723"
                     /pseudo
     CDS             complement(13904..14352)
                     /locus_tag="ACL3S0_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(14357..14746)
                     /locus_tag="ACL3S0_001724"
     CDS             complement(14357..14746)
                     /locus_tag="ACL3S0_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HGR1312599.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHFYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(14773..15423)
                     /locus_tag="ACL3S0_001725"
     CDS             complement(14773..15423)
                     /locus_tag="ACL3S0_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR1312600.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIR
                     GDLPDYLTILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(15413..15976)
                     /locus_tag="ACL3S0_001726"
     CDS             complement(15413..15976)
                     /locus_tag="ACL3S0_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR1312601.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGFSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(16141..16375)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16429..16932)
                     /locus_tag="ACL3S0_001727"
     CDS             complement(16429..16932)
                     /locus_tag="ACL3S0_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGR1312602.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(17125..17955)
                     /locus_tag="ACL3S0_001728"
     CDS             complement(17125..17955)
                     /locus_tag="ACL3S0_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR1312603.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLATMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQTLKKGDYITLLLATLFLVASLLLILQNQGRFYNPWK
                     "
     gene            complement(17940..19622)
                     /locus_tag="ACL3S0_001729"
     CDS             complement(17940..19622)
                     /locus_tag="ACL3S0_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312604.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQIQLQTELVKETPALQSLFILEEVSFSYNDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVNEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRALVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
BASE COUNT         5715 a         4437 c         3647 g         6030 t
ORIGIN      
        1 ttctatatta gtaaaggtct aaataattat caatttccca ttgtgaaacg aaggttgcat
       61 aacttgccca ttcgattcgt ttggcttcaa ggaagctagt gtagatgtga tctccgagag
      121 cagctttaac cacttcatct tctgtcaaag ctttcaaagc gttgtgaaga gttgatggaa
      181 ggtctgtaat accagcttcc ttgcgctctt ctgctgtcat gatgtagata ttttcttcga
      241 taggagctgg tgcttcgatt ttattttcaa taccatacaa accaacttcc aaaagaacag
      301 ccatagcaat gtaagggttc gccattggat ccactgaacg caactcaaga cgagttccca
      361 taccacgtga agcaggtacg cgcacaagtg gcgaacggtt acgaccagcc caagcaatgt
      421 aaacaggcgc ttcataacct ggaaccaaac gtttgtatga gttaactgtt gggttcatga
      481 tggcagtata gttgtaagca tgcttgatca aaccgcctag gaaatggtaa gctgtttctg
      541 acaactgcat tccttttgga tcatttggat caaagaaggc gttatttcct tctgcatcaa
      601 acaaggacat attacagtgc atacctgagc cagcaatacc aaattttggc ttcgccataa
      661 atgttgcgta aagtccgtgt ttgcgagcaa tggttttaac aacaagttta aagatttgaa
      721 tcttatcaca agcacggaga acttcatcgt acttaaagtc aatctcatgc tgtccaaccg
      781 caacctcgtg gtgactcgct tctacttcaa atcccatttt ggtcaagaca ttcacaatct
      841 cacgacgtgt gttgtccgca aggtcagtag gtgccaaatc aaagtagcca cccttgtcat
      901 tcacttcaag tgttgggtcc ccattttcat ccaacttaaa taggaagaat tctggctctg
      961 gaccaaggtt gaaggatttg aatccaactt cttccatgtg acgaagagct cgtttcaaat
     1021 taccacgagg gtcacccgca aatggttcac cttctgttgt ataaacatca cagatcagac
     1081 ctgcaacact tccattttca tctccccaag ggaagactgt ccatgtatcc aagtccgggt
     1141 acaagtacat atccgactca ttgatacgta caaaaccttc aatagaagat ccatcaaaca
     1201 taaccttgtt cgacaagacc ttatctaact gttcatctgt agcaggaatt tcgacgtttt
     1261 tcatggttcc caaaatatct gagaacataa gacgaataaa ggtaacattt ttttccttga
     1321 cttcacgacg aatatctgca gctgtgattg gcataagttt tctccttaat ctatgactac
     1381 ttgcggttgc ctaaccgcga ccaaaaggtg actgtactga agcaaaacgc ccctgttgga
     1441 ggagttcatt gtgaagtgca cgacgtactt cagtctgact aaccgctttc ttggatttcg
     1501 cttcacgttc agcatatttt ttcttaatgg cagcgatatt ataaccttca gagatataat
     1561 ctttgatttc aagcagacga tccatgtcat tcaaggaata catgcgacga tttccttcgt
     1621 ttcgatcggg cttgatcaac tcttgatctt cataataacg aatctgacgc gccgatagat
     1681 cggtcaactt cataacactg ccgataggaa aaacagccat atttcggcga aattcttttt
     1741 ccttcattta caatttcctt ctttctgtct attatagtct aaaaaaagac aaacgtcaat
     1801 tgataatgtt ataaaatgta acattatttt tcttttttct ctaaaaagag acgaatacga
     1861 tcaatatcgt aatttacgat aattgcgaca aaaactccca taaacgtttc taatacacgc
     1921 acaaacacgt acaaaattgt ctcaccactt ggaattgata gggtaatgat taacatagct
     1981 gctacaccac caataacccc tgctttgtta ttcatggcta catttgtcat aatggttaac
     2041 atggtgcaga ttggaacaac taccaaggtc acccaaaagg cttcgtggaa aaaggtattt
     2101 aataagaaga agaccaaggc atagagtcca ccgatactat ttcctagaat acgcgaagtc
     2161 ccaaaatgaa cactctcatc aaaactctcc ctcaggctaa aaacggctgt caaagcacca
     2221 atttgaagac ctttccagcc aaaaaagcca aaaatcaaga gaactagaaa aacagcaata
     2281 cctgttttaa aggttcgcat accaagtttg aactgggatt tatcgaattt atatttttta
     2341 aaataactca taatctcaac tttctatttc cattttatca taaatcggtg atttttatga
     2401 gtaatagttg agaggaagcg tttttatttt aagcaaaaga aaagaggaac tttcatccct
     2461 ctcttctttg atttgtttat aaaatcttat ttttctgtca aggctgcaag tcctggaaga
     2521 accttacctt caagaagttc cattgatgct ccaccacccg tactaatcca tgagaacttg
     2581 tctgcacggc caaggttaat cgctgcggca gctgagtcac caccaccgat gattgattta
     2641 actcctggtt gtttcacgat agcgtccatc acaccgattg taccagcttg gaaatctggg
     2701 ttttcaaata cacccatagg tccgttccat acaactgttt tggcaccagt caaagcttcg
     2761 tcaaatttgg cgatagattt tggaccgatg tcaagaccaa ggaagccttc agaaactgct
     2821 tcaccttcag tgtcacgcac ttcagtgtaa ccagcaaatg cgttagcttc ttttgagtca
     2881 actggcaaga tcaatttacc atttgctttt tcaagaagag ctttcgcaac atccaatttg
     2941 tcttcttcta caagtgagtt accgatttcg ataccttgtg ctttgtagaa tgtgtaagtc
     3001 atcccaccac cgataaggac tttatcagct ttttcaagca agttttcgat aacaccgatc
     3061 ttgtctgaaa cttttgaacc accaaggata gccacgaatg gacgttctgg agtttcaact
     3121 gcttcttgga tataggcaat ttcgttttca agaaggaaac cagcaactgc tttttcaacg
     3181 tttgctgaga taccaacgtt agatgcgtgt gcacggtgag ctgtaccgaa tgcatcgttt
     3241 acgaagatac catctccaag tgatgcccag tatttaccaa gttcaggatc gtttttagat
     3301 tctttcttgc cgtcaacatc ttcgtaacga gtgttttcaa ccaagagaac ttgtccatct
     3361 tcaagaacgt tgattgccgc ttccaattca gcaccacgag tgacacctgg gaaaacaaca
     3421 tcttgaccaa gttttgctgc caagtcagct gctacaggag caagtgattt accagcttta
     3481 tcagcttctt ctttcacacg tccaaggtga gagaaaagaa ttgcacgtcc accttgttcg
     3541 atgatgtact taatagttgg aagagctgct gtgatacggt tatcgttagt gattacgcca
     3601 tctttcaatg gtacgttgaa gtcaacacga acgaggactt ttttaccttt caagtcaacg
     3661 tctttaacag taagttttgc catgttacaa aaactccttt atttatttta ttcgaaacta
     3721 ttatatcaca ctttggaaat ataaggaaag atttcacaag atttttcgat atttaatctt
     3781 tatcttctct tttccgtctc aaggtcaagg ctaaactagc aagaccaagg ctggctaagc
     3841 ctgctattag ggcttcatta gcatcagctg ttcctgtatt tggcaattgt ttgcttgctt
     3901 cttctgattt aactgctgta ttttgagctg gtttttcctg tgtagctact actgctggta
     3961 ctgtttttac ttttgttcca atttcaacaa tttctggaat cgcttcttgg atgacttctg
     4021 ttgaacgaag acgacgctga ccgttttcat caacttcaaa gacatgtctt aacagtccat
     4081 ctcgtccctg tatgatgact cgttgttccc caactagcat ctcagcattt tcatgctctt
     4141 gacgatgaaa ggcaaccttt tcctcttgaa cttccaattt aggagccttt tgttgatcag
     4201 aagccggttg ataagtaggt tttggaagga ctgtgttttg tggtgctggt ttagcaggtt
     4261 gtggtttttc agcagattca taaacaaagg cataatgagt aaagtgaggt gctgtaaaga
     4321 taacatgact atccgtttgt tcaaaagcca attctactgc ctctttgcct tcaggtaaga
     4381 aaaatacttt cttaactttc ttatcttttt caattgggat tttcacaata gaagcgtaag
     4441 agagatcaac atcttgacct ttttcatcca aaccttctat ttcaaagaca tgagcatctt
     4501 ctccagcaaa gtatttcttc tcttcagcac ttgcttgaac acgctctact ttcaaaccct
     4561 tgatgacagt cttctcttta tttgagaagt gtacttcaac acctgtttta ctatcagaaa
     4621 agactgctgg cttgtcttct ttcaataaag caaccagatc ttttagactc tgtttcgctg
     4681 ttgtaagctc ttctggactc aaatctactt tttcaaccaa ggccttgttt ttctcaagaa
     4741 gcggagctag ggcagaacct gaaggatggt ttggtttggc agccaagagt tcttgaacct
     4801 cacctgttaa gcgatcaagt tctgtctttt cttccttaaa tttctcttga ccattcagag
     4861 ctttatgagc ctctgtcaat ttattaagtc ggtcattgac ttgatcttgg gtgctagttt
     4921 catggtcttt caacacttgt tcggccgctt caattgcttt caagaaagct tcttttactt
     4981 ctggtgaagc aaagttatag accaccttgt tcttagcagc ttcaacttct gctaattttt
     5041 gtttgaggta ctcatcgttc aatgctgctt ttggagatac caaaacatca aagctaactt
     5101 catggccttg gtaatgaagc gtcaaggttt gacgaccagt cttttgagca tcgtaaccag
     5161 aaatttcaac tccctcatca gtaaaggaat gttcttccat ggtgtcattg ctataagcca
     5221 ctgcaaagcg tccttcagac aagtctaagc tatcaccaac taggtaatct tttttcggtt
     5281 cctgacttac ttcaattccc aaaatagttt tcggacttgc ttcgtctttg ccagtgacag
     5341 tcactgacaa attagcattt accggttgtc ccaaatattg gagagtaaga ttctgttctc
     5401 ccttatgatg cgtatcaaaa cctgatactg atacacctgc gtgagttagg cgaatgagtt
     5461 cgtcctcagt tcctccttca tactgaactc gaagaacacc acctctaaga tccaaatcct
     5521 ccccttcggc gtagcttgtt ttcttaggtc ctgtttctag gctgactgac ttgattcttc
     5581 tgtcatcttt tggaacggaa actgctagga cattactaat ttccttgcct ggcaactggg
     5641 tacgataata aagaagacca gattgatttg tcaaatccaa tggtgcactt gctaggtctc
     5701 ctccaacttc gctcttcaag gttgcaagcg gagtttgaga atttggatta tcataaacag
     5761 taatagttgc tccagccggt acatctgaaa agccaacttg taccttgtta ttgcctagag
     5821 aacgggctgc agccttggcc atcggaatat tgacactctc agtatcaagc ttttcataca
     5881 ttttccagtt atagatacga atagccttcc atggagttcc attgtcagaa gtgacaacat
     5941 tcaagcgcca gtcttgagca gtgattggtt tatcaagagt gatatctgtc acgtgtgctt
     6001 tgttgccacg gacttcctta gctagcttcc actcaccatc tgcatcttta taataaaggt
     6061 caaagtcttt ggtgttcatc aagccatcgt taacagactc accaccagcc cctgcatgat
     6121 ccatgaccca tctaacaacg gtacgtggct tggtcaaacg aatatccaca ctaccactca
     6181 actgagctga agaccattta tctgacaagc tagtaatggt accgttcaac ataccttcaa
     6241 taccttctcc accttcagtc ttagggaaag tactatcaat aactgttgca cctggaacga
     6301 tattttcagc tagtggtttt ggtaggctgg tatcttttac agtcataccc caatcaaagg
     6361 ttgtggttgc agcttctgaa cgaactccat ttttaccgac tgctacaacc ttcagttctt
     6421 gagttgtacc ctgagcactt gctgagcggc taacttttgg tagataaata gttgtagaag
     6481 atgagccagt tagtaatttc cagctgtctc catctttttc ataaacttca tagaaatctg
     6541 catccttgtt gcctttaaat tgcacaactg cttccgcttc ttgggcattt ttaagagatt
     6601 gtttcactac agaaaagctt gtcggcgatt gtggctcttg gtgattgtcc gagatagtta
     6661 attgtccgag gttgaactga taatctttta cagcaccttc atgctcgaaa aatagtttaa
     6721 ctgcatagat ggttttacct gctagtgagc tgagatcaaa ttcttcattt gtccagttgt
     6781 cagaaagggt tagctctttc catgcatctg catcatcgaa tttgtagtct gaagttgtag
     6841 agaatgccat ataaacttta gaaccttttc ctcccttgtg ggcaacacga agtttggtct
     6901 tctcagttac ttctaactta gtagaataaa gtctcacatc ctgaactgtc ttaccggcta
     6961 catcaccaga gaatttaagg gaatttccgc cattataggc atctgtaaaa tcatattctg
     7021 cacgaagttt ttcccctgtt gaagtctgcc accagcgcca tgttggaaga acacctgata
     7081 ctgaacgata attccactca gaatccttag aaaccttacc atctacgaac cattttttac
     7141 catgacctgt attaaaagaa gtagtaaaag tattacctac cgctggcgta cggtccgcaa
     7201 ctaggttagc aataccatac caatctttgt cacctggttt ttggccagtg gggtctcctt
     7261 gataacctgt aaagaagata tcttcatttt tatgataatc ttcaccagtt tttcctaaac
     7321 ttgtaatggt atctggggca aataaaccaa gagaaaggcg caatttccca ttttcgtcta
     7381 aaatgtcatt ccacttaacc tttgtcttgt aggaaccacc ctgttgcaat tccaaacctg
     7441 caaatacatc ataaggatta cgaccaatcc agttggcagt tgcaatagtg taatcatttt
     7501 tagccttatc ccagttaaag ttagcaaaga agttatctgc cggaacctta tctccttctg
     7561 gttgcatgaa ttggtagttg tattctccca aaccatcttg atggtaacgt ccatagttat
     7621 aggtcatggc atcataccaa gaatacttga ttggatggtt taccttagca gcatattcct
     7681 tgctatagag cataaactgg cgcatctttt ctccaagagg tttaaccaaa tctccagttg
     7741 tttcttggtt gatgaaatag ccatcatagc cataatactt ggccatgtct accaatttac
     7801 gggcaattgg gaagctacca tctgcgtctt gcttcaaagc ttcagcaaat ctttcttgat
     7861 ctgcaatact attagaccag ttgaagaaga gtgtaccgta tacaggaacc ccgttacggt
     7921 gacctgcatc aataacgtca ggagttggta cgagaccttc ccagaagacc attgaatcta
     7981 gatattgcca atagtcaaaa gcataggcct tgaactcttc tccaccaaca gaagcatggt
     8041 cttttgcttt agaattagtg tttgataagg cttgaacttt tgcttccttg ctagcttttt
     8101 cattgactaa atgacctgtc cgacgtgaag cgaggacaac agatccgcgg ttaatagcat
     8161 catcttcacg agcacctggt tcccatttta acaattcttc ccaagaatta aatttgattt
     8221 cctttggttt taatgttttt tctgtatttt tagggacatc tggctggact tctttttcag
     8281 tcttattagc ttctgctgct ggcttagact catccccttg gttagttgct tcgggctttg
     8341 cttctgtttc cttgtcagac ttaggttttg cttctgcaga tggtgtttct gcaaccgcct
     8401 cacttgcttt ttcctctggt ttagctgcgc tagctgcttc tgcagtttca gatgctgtcg
     8461 ctactccttc tgccttttct agcttgtttt ctctagtatg ttccccttca ttctgcttat
     8521 cagcttcatt ggtcgaatgc tcactctctc ctgaaacaag ctctgtatta gctccgctat
     8581 tttcaggaac tgcagtttct tcagccaagg ctggaccagc aaataaaaca gcaccaatca
     8641 tcagcgagca ggctcctact gataacttac gaatactgta acgacaacgt ctttcaaaaa
     8701 atggattctt cattttctcc tcctaaaaga ttgattttgt tgtttttaag aaagcgcttt
     8761 atattctgtg gttttttaac tctagaacca tgataatcac atttttatcc taaaacattt
     8821 ttagacaaaa aacaatagct gttttcacaa atctaaaata aggttaaaaa ctcttaaaaa
     8881 taatacactt atcaattata attttctttt acaaacttga cattaacact tgttagattt
     8941 acttttatcc tttaaaatag aataggagat attccgcgat tatttttcgg aggaaaaaga
     9001 aatgtccatt aattggcagg aaattttatt tcacttttta ggtggtctgg ggctattctt
     9061 atatagtatc aagaccatgg gagacggttt gcaacaagct gctggagatc gccttcgttt
     9121 ttacattgac aaatatacta gtaatccttt ctttggagtt ctggttggta ttgggatgac
     9181 tgctctaatt cagtctagtt ctggtgtaac agttattaca gtcggcctgg tcagtgccgg
     9241 tctcttaacc ttacgtcagg ctatcgggat tgtcatgggt gctaatattg ggacaactgt
     9301 cacatccttt ctcatcggtt ttaaattagg taactatgcc ctacctatgc tctttatcgg
     9361 tgccgtctgt ctctttttta cgaaaaatcg gacagtcaat aatatcggac gcatcctctt
     9421 tggtgtcggt ggtatctttt ttgccctcaa tctcatgagc ggcgcaatgg ctccactcaa
     9481 ggatttacag gtctttaagg actatatgat tgagctaagt aagaatcctg ttttgggtgt
     9541 ctttgtcggt actggcttga ccttgctaat tcaagcttct tcggctacca ttgggatttt
     9601 acaaaacctc tacgccggcg atctaattga cctacaggga gctttgccag ttctatttgg
     9661 tgacaatatc gggacaacca ttacagccat cattgcctct ttaggggcta atattgcagc
     9721 taaacgggta gcaggagctc atgttgcctt caacgttatc ggaacagtcg tctgcgttat
     9781 ttttctagtt ccttttactg tcctgattca ttggtttgaa actacgctaa atctagcacc
     9841 ggaaatgacc atcgcctttg ctcacggaac ctttaatatt accaacacca ttatccaatt
     9901 tccatttatc ggagctctgg cttactttgt aaccaagatt attcctggag aggacgaggt
     9961 tgtcaaatac gaacccttat atcttgatga acatttcatc aaacaagccc catctatcgc
    10021 tctaggaaat gctaaaaaag agctcttgca cttaggaaac tacgctgcta aagcctttga
    10081 cctttcctat aagtacatca ttgacttgga tgaaaaagtt gctgaaaaag ggcataaaac
    10141 cgaagaagca attaacacca tcgatgagca attaacacgt tatctcattg ccctttcaag
    10201 cgaagctctc agccaaaaag aaagtgaagt gcttaccaat atccttgatt cctcccgtga
    10261 tttggaacgg attggagacc acacagaggc tctactcaat ctgactgact atcttcaacg
    10321 gaaaaatgtt gaattttctg atgccgcctt gaaagaatta gaggaagttt accgccaaac
    10381 tagtgacttt atcaaagatg ctctggatag tgtggaaaac aatgatattg aaaaagcacg
    10441 cagtcttgta gaacgtcatg aagcaatcaa taagatagaa cgtgttctca gaaaaaccca
    10501 catcaaacgc ctcaacaaag gcgaatgttc aacacaagct ggggtcaact ttatcgacat
    10561 catctcacac tacactcgtg tatcagacca cgctatgaac cttgctgaaa aggtttttgc
    10621 agaacaaatc taagaaccaa gaagctatcc atcataattg gatggctttt tactttttcc
    10681 taagcaagac taggctgaat gaaactgaaa gagtattctg cagatatata gtatattgaa
    10741 actagaatag gacacctcta tttctaaaac attgttagaa atagatttga ctgtcctgat
    10801 cgatttgtcc tgttattatt tcattttact atagtgaatt aaattaaaaa agtatagtgt
    10861 attgaatcta taacagtcca tcttaactgc taaaatattt atataaatta atttgacttt
    10921 cctgatagag atgttcacat cttatttcaa ttcactatac aatccagttc ctaaaacttt
    10981 gctagaaatt gatttggctt tccgaattaa tttgttcaga ttttatttca tttcaatata
    11041 ctgataaatc cattcactag cacagggcaa gagggagtcg ctattgattt caacggtagc
    11101 aggtacatac agaggactcc tacctcagat atactgcaat atcatcgtgt gcaaaaaacc
    11161 tctgagattt ttctcaaagg ttctgatttt gctaattgct gttctcaacc gctgcagtaa
    11221 caaaggcaat gtagagttct tctggtcggt ttggacggct tgacagttca gggtgatact
    11281 gacaagctac aaagaattta ttttcaggaa tttccacgat ttctaccaaa cgattgtctg
    11341 gagaaactcc tgaaaagaca aagcctgctg cctcaaactg ctcacggaag gcattattaa
    11401 actcataacg gtgacggtga cggcgttgca ccacttcttg attgtgataa gcagcagcag
    11461 ccttagagcc acgtttcaac ttagacggat aaagtcctaa acgaagggtt ccacccatat
    11521 cctcaatatc aatctgatca cgcatgatat caatgatagg gtattttgtt tctggtgcaa
    11581 gctctgcaga attggcacct tcaagaccta aaacgtgacg agcaaactcg atacatgtca
    11641 actgcattcc caagcagact cccaacattg gaacatcatt ttcacgcgca tagcggatgg
    11701 cttggatttt cccttctgta ccacgttgac caaaaccacc tggtacgatg atcccgtctg
    11761 catcagacaa gagttctgct acattctctg ctgtcacatc attggcattg acccaattga
    11821 ttttaacttc tgcatcattg acatagccag agtgtttcaa agcttcgacc actgagatat
    11881 aggcatcttg caactccaca tacttaccaa caagggaaat cttaacttgt ttcttgaggt
    11941 tcatgacctt gtccaccatg gctgaccatt ctgtcatatc cgctgctggt gcgtctaatt
    12001 tcaaatgatc acaaacaatt tggtccatcc cttgtgcctg caagttcagt ggaatttggt
    12061 aaaggtgttc aacatccaac gattcgataa cggcttctgg tgccacatca cagaactggg
    12121 ccagtttatt tttaattcct tgaccagctg gctcttctgt acgaataacc aacatatttg
    12181 gttggattcc caagccacgc aattctttga cagagtgttg ggttggtttg gttttcattt
    12241 caccagcagc cttgaggtaa ggaagcaagg ttgtatggat atacatgaca ttatccgcac
    12301 ccacatctgc cttcatctga cgaagagcct ctaggaatgg caaggactcg atatctccta
    12361 ctgttccacc aacctctgtg ataatgacat cagagtcggt cgttagagcg gcacgcttga
    12421 ttttttcttt caaagcatct gtgatatgag gaatgacttg aacagttgcc ccaaggtatt
    12481 ctccacggcg ttctttacga agaacttcac tgtaaatttt cccagttgtc acgttggaat
    12541 atttgttgag attgatatcg atgaaacgtt catagtgacc caagtccaaa tctgtctcag
    12601 ctccgtcatc tgtcacaaaa acttccccgt gctggtaagg actcatggtt cccggatcaa
    12661 tattgatata agggtcaaac ttttgaatgg ttactttgag accacgattt ttcaagagac
    12721 ggcctagact cgctgccaca atccctttcc caatagacga taccacacca ccagttacaa
    12781 aaatatattt cgtagacata gattcctctt tctaaaatgc tcaaggtctt gttaactacg
    12841 aggggatata gaaaacaaga ccctactaat aagaataatc tgggacgact gcaccagatt
    12901 cacaactaat actcttcgaa aatctcttca aaccgcgtca acgtcgcctt gccgtagata
    12961 tgtgttcctg actttgtcag tcttatctac aacctcaaaa cagtgttttg agcagcctac
    13021 ggctagtttc ctagcttgct ctttgatttt cattgagtat aaaatacaag aagataactt
    13081 cttgaaaaaa caaaaatagc tccctaagaa ctagggagcc ccgacctcta aaagaggtgc
    13141 ccaaacaata tgatacctaa aaataggata attgtcaata gctaactctt attcctcgct
    13201 ggtttcagcg tcgtcatctg aaaactcgtc gtcgtcttcg ttgagatcca catcttctcc
    13261 caagtcatct ggagcgattt cgttgatttc tgcatcataa gcttccactt catttttttc
    13321 atcatctgga ttttcatcat cgtatgaaag agctggatct gcttcgtatg catcttcgtc
    13381 ttctggatca tctgcattgt agtcaatggc atctgaatca ccatccataa aggcattgac
    13441 acgttttttc ttagcttttg gtgctacttc atcgtcgtca ttttcttcaa gagcgatgat
    13501 ttcttcgtcg atttcgtcca caccatacca tgaacgaaga ccccatttgt tgtccccaag
    13561 tgagatgaag ctaccgtcaa agttcaactc tgtgtagaac aaaggcaaag cttcgcggat
    13621 atcgctgttt gatgttccaa ggtagttttg aatttcgttt acaagatcgc taaaatgcat
    13681 ctcatgatcg cgaccacgaa gttctaagat agcacgcgct acctcaatca tagatagttc
    13741 acttttttct tgcccagcaa atacttctaa ttccaaagcg tttctcctca tttatactac
    13801 tatcgtcaga gcgaacagac tctgacctca ttttatcatt tactctttat tttacgataa
    13861 ttttgcggaa tagtcaaagg ttaaggggga gaaagtggca ggattagact aattccaata
    13921 taaaacccct tcctttttct gttgctccat tttccacaaa tccaagcgac ttgaaacacc
    13981 tcctagaagc atgattgtag gtgtagattt ccttgactct caattctttc catcctttta
    14041 ctcgagccaa ttcaatcaaa gcacttagaa tctttttcca agtcctcgat gttggtaagc
    14101 ggaattccca atcacaatgg ggagattatc ctgagatagt gtaatatccc caattggaaa
    14161 ccattctccc ttctccttga cttcaatcca aaaaagctca ccatgccgat ccaaatagga
    14221 atacatggct tccaaggtcg cttgactgta aggaagcttc accccatcta cgaggtaaac
    14281 caagttcaca tcctgatacc aagcaaaagc ttcctcacaa tgattgacct tataataagg
    14341 aacaaaacac aatgcactac cttttcaaca aaagagttgc tgcttgatta aaaccatcac
    14401 accagttata ccattttgct tcatacccat cttgagctag gatacgatct tctaaatcaa
    14461 aaacagagta aatctttctt tcctcgcaag cttgcgcata gaaatgatat agttcatcac
    14521 caccatctct atcccactca gcagaaatcg tatcccgacc tgccaataaa gcctgataag
    14581 ccctgtgatg cccatctgta atcagcaaac aatctccaaa ggcaagaata ctgattggat
    14641 cgacttggat tgtttctgcc gactggtaaa gcatctgaat atcttgcaac ttcttttctg
    14701 ataaatatag ttgagtcgga tgaagatctg ctatattgac tttcatttct ttctctcaag
    14761 ggaattcgat actcacttct gtttgccttt aaatcgccat tggaagcgga gcttgtcata
    14821 aaagggaaac tcgataaaca ggactcccaa gcccacacag agactggcaa ggacgtctga
    14881 tgggtaatga actcccagat agactcttga taccagcaca ctgactaggt agaggccaag
    14941 gacgatttgt acgatttttc tccagacctg atctttaatc cgctgactaa gaataacaat
    15001 caaagtccct accatcagcg ttacagctag agaatgccca cttgggaagg aaaatccctt
    15061 ctcttccacc agatgtaaga tagctggtcg tgggcgctgg tagatatttt taaaggtcac
    15121 gattaaaaga cctgccaaag ccagatttcc cagcatgaag aaactttcta tcttccatcg
    15181 cttacgataa aagacaaaag ctgtaatgac aacccaagtg ataatcactg ggatatcaat
    15241 cagacgtgtg agggctcgaa aaagaatagt caaataatct ggtaagtctc ctcgaatggc
    15301 agtctgaatc gattggtcaa aattgaccaa catttcaggg taaaatttga ccatatagcc
    15361 aagaataacg aaaagtaaaa gggcaaaact gcccttcatt aaaaatgttt gtttatcttt
    15421 catagtgttt taaggttggt ttcaaaagga cgtacaacaa ccagaatgaa acggaaaaga
    15481 ttacaccctc aatcaagtta aaaggtaata ccatggtcat taggtagttg gaaaatccca
    15541 aaatttttcc aatatcaaag ttagcaaact tagcgtacaa aggaacagca taaacatagt
    15601 tgagaaccaa catggccaag gttaaaccaa tagttccagc tagagagcct agtaggaaac
    15661 gaagggttgt ccgttccttt ttccaaatca aagcaaatac gatgacaaaa actcccaaag
    15721 ctacgatatt catcggcaaa ccaatgtaag tattcactcc ttggctgtta agaagcaatt
    15781 tcaagagtga gcgaagcaag agcactccta gagcagcagg caaatccatg accaccagac
    15841 ccacaaggac tggcaagata ctaaattcga tcttgaggaa agatgccgct ggtaaaagcg
    15901 gaaagtcaaa gtacatcagc acaaatgaga tggctgatag aattgcaatg gtcgaaagtc
    15961 gacgtgtgtt tgtcataaca ggttcctcca attttctata aaatcagaag aagttggaaa
    16021 ggattcctct atctattctc actttttata tcccaaaagt tccctcttac tctattaaag
    16081 aaaaacaaag caagtggtta caatccggct ataaatctat caaaacagac aaagctattc
    16141 tttcgtcttc tcccatccag actatactgt cggttgtgga atctcaccac atcagcttgc
    16201 gctcgcggac ttctttaaag agaaggaaat agagattttt cttttagact aggcgacaag
    16261 ctgtaggcat aacttctggt taggcaaagc ttgtcaacaa agtataaaag gaaaagatca
    16321 tttcctagtt aaagtcaccg ccggtcggga atcacaccct gccctgaaga ctcttttatc
    16381 ataacaaaaa acgcttgcaa gcgcaagcat tttgttcatt ttcatttttt atttcaattt
    16441 atccacttca taggtatgga cgagctcaag acctgcaaag ttctgctggc gaagagcctc
    16501 atagacaatc atgcagacgg tattagacac attgagactg cggacatgtt catcattcat
    16561 gggaatacgg agagccttct caggatgttc tcgcataaaa tcttcaggta agcccttgtc
    16621 ttcacgtcca aaaagaaaat aatggtcctc gtcagtcgat aaatccacct cagaatagac
    16681 tttttccgcg aatttcgaaa tcagatagag ttttcccttc atctgagata tgaaatcttc
    16741 caaactctcg taaaaataaa tctctagctt atcccagtaa tccaatccag cccgcttcat
    16801 cttgcggtca tcaataggaa agcccatagg cttgatgatg tggaggggag aattggtcgc
    16861 agcgcaagta cgcgcgatat tgcccgtatt ttgtggaatt tgaggttcaa ataatacaat
    16921 gtgatttgtc atgacttgct tcctttcacc attgcaaaaa aatagccaca ctgcccggag
    16981 tcaagctcag cagacagcgt ggttaaggca tcgttaactt acctcacaac aggtttgaag
    17041 taaatcagcg aaactacttt cttagtataa cactttcaga atcattgtca atagaaacga
    17101 cttgattttt tcaatttttt caagctattt ccaagggttg taaaatcgtc cctgattctg
    17161 caagataagt agtaaactag ctactaaaaa caaggttgcc aagagcaagg taatatagtc
    17221 tccttttttc aaggtctgat aactatacca tgtgcgtttt ttctctttcc caaagcggcg
    17281 aagctccatg gcagtcgcaa tggtatcaat gcgttctagc gagctaaaaa tcaagggcgt
    17341 aataatgagc agattgcctt tgattcgttg cataagagaa gctttcttgg ataattccat
    17401 cccacgcgcc tcctgagaca tcttgatagt aaagaattct tcctgcaaat ctggaatata
    17461 gcgcaaggtc aggctgacag aataagcaat cttatagggc acaccaattt gatttaaact
    17521 ggaagcaaac tgactaggat gggttgtcat caaaaagata atagccagag gaatggtgca
    17581 aagatactta atggccaaat ttagcagata aaagagctcc tggctggtta gagtgtagac
    17641 accgattccc tgccaaatca cacttctctc tccataaagt ccaaccccat actcgggaga
    17701 aaagagatag accatcaaaa cgtttaaaac ggcaaatacc gtcgcaaaaa cggctacaaa
    17761 ggaaacatct ttaaagcgaa tttctgataa atagaggaga aagactgaaa agatggcaat
    17821 cagcaagagc attctggtat catagctaat catggtcgcc aatgatacca gaatgaaaaa
    17881 gagaagtttc ccagctcctg acaagcgatg aatcacagta tctctatgct ggtaaccgat
    17941 taatttagct tgcatccctc tctcctctct ttgtaaaatg ccgttaaatc caatggatcc
    18001 acatctagtt tcttagccaa gttaaagatg gaggtttctt ttagattggc ttttactaac
    18061 agctcaggat cgctcaacag actggctgga acagtatcgg caatcaattc tccatccacc
    18121 atgacaaggg ctcgatctga ataatccagc atcaattgca tatcatgggt aatcatgaca
    18181 atggtatgcc cttgttgatg cagttcttcg agaaattcca taatctcagt atagttcttc
    18241 tggtcttgac ccgcagtcgg ttcatctagg aggataattt cagcgcctaa gaccaaaatt
    18301 gaagcaatgg tgacacgttt tttctgacca aatgacaggg cagaaatagg ccaattacgg
    18361 aattcataaa gtccacagat tttcaaggtt tcatagactc tcgtttcaat ttccttctca
    18421 ttcacacctc gcaaacggag ccctagagcc acctcatcaa aaatcatatt ggttgaaatc
    18481 atttgattag gattttgtag cacatagcct actcgttccg cccgctctgc aacagaatcg
    18541 ccttttatat cctgtttttc ccaaagatag cgtccttccg tctgaataaa gctacttata
    18601 gccttggcta gagttgattt ccctgctcca ttttttccga caatagcaat cttttcaccc
    18661 tttttaatat ctaaatgtag ggattttaaa atcggtctat cattataaga aaaagatact
    18721 tcctctagta taaagagtga ctgcaatgct ggggtttctt ttaccagttc cgtctgtaac
    18781 tggatttgcc cttttgagat agacaagtta tccagatctg ctaattgttc ttccttgact
    18841 aagtccacac ctaattgacg gagagtcgtt agataaaggg gttctcgaat tccattttga
    18901 gtcaataaat cagtcgcaag caactggtca gggctcccat taaaaaggat acgaccatcg
    18961 tttatcaaga caatccgatc cacagggcga tgcagaacgt cctccaaacg gtgctcgata
    19021 atcagagtcg tcgtcccctc ttccttatga atctggtcaa tcaattcgat aatatcctga
    19081 cctgacttgg gatctagatt ggcgagtggc tcatcaaaca agagaatcgg actttcatca
    19141 atcaagacac cagccagact gactcgctgc ttttgtccac ctgacaaatc ctgaggacgc
    19201 tgatccagta aaggaagaag gtccagcttt tcagcccatt tataaacacg acctttcatc
    19261 tcatctaggg ctgtcacatc attttccaga gcaaacgcca aatcttctgc cacagacaag
    19321 ccaataaact gcccatctgt atcctgcaaa actgtgctaa ccagatgaga cttatcatag
    19381 atgctcatat caaaggctgt ttgacccttt atcaaaaatt ctccatatgt ctgacccttg
    19441 taaatattgg gaataatccc attcaaacac tgacccaagg tagatttacc tgatccagat
    19501 ggtccaacaa ttaagacttt ctctcccttg taaatggtca agtctatccc ttgcaaggtc
    19561 ggttcttgtt gtgtttcata ccggaaagag aaatccttcc actcaattat agcttctttc
    19621 atcttactct cttcattcgc ttcttagact tctattttat cataaatcaa gcccttcttg
    19681 cagtctcttc tcttaaaatc ttagcgccaa aaagattcct atcctagctt acttgcctaa
    19741 ctaatctata aacatcgaaa aagactagtt gcccagcctt ccccatcatt ttatactctt
    19801 cgaaaatctc ttcaaaccac gtcagcttc
//
LOCUS       DBEJZV010000037        19647 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.37, whole genome shotgun sequence.
ACCESSION   DBEJZV010000037 DBEJZV010000000
VERSION     DBEJZV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19647
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.37"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..1056
                     /locus_tag="ACL3S0_001730"
     CDS             <1..1056
                     /locus_tag="ACL3S0_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGR1312605.1"
                     /translation="KEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFK
                     NIAHKNVLSFLDRVNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIE
                     RYQEKGGFIQAWGDLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASA
                     NNVIRDDASSFHTFYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKD
                     ESCFDLFKGVTNYFLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLP
                     EVDADKDIYKHAMHAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDY
                     YYLEALIRFYKDWNLYW"
     gene            1067..1558
                     /locus_tag="ACL3S0_001731"
     CDS             1067..1558
                     /locus_tag="ACL3S0_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1312606.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            1573..2352
                     /locus_tag="ACL3S0_001732"
     CDS             1573..2352
                     /locus_tag="ACL3S0_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR1312607.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            2339..3157
                     /locus_tag="ACL3S0_001733"
     CDS             2339..3157
                     /locus_tag="ACL3S0_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR1312608.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3157..3450
                     /gene="yajC"
                     /locus_tag="ACL3S0_001734"
     CDS             3157..3450
                     /gene="yajC"
                     /locus_tag="ACL3S0_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR1312609.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            3472..5373
                     /locus_tag="ACL3S0_001735"
     CDS             3472..5373
                     /locus_tag="ACL3S0_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGR1312610.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLIDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKGYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            5433..6434
                     /locus_tag="ACL3S0_001736"
     CDS             5433..6434
                     /locus_tag="ACL3S0_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1312611.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(6544..6879)
                     /locus_tag="ACL3S0_001737"
     CDS             complement(6544..6879)
                     /locus_tag="ACL3S0_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312612.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(6890..7132)
                     /locus_tag="ACL3S0_001738"
     CDS             complement(6890..7132)
                     /locus_tag="ACL3S0_001738"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312613.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7148..7342)
                     /locus_tag="ACL3S0_001739"
     CDS             complement(7148..7342)
                     /locus_tag="ACL3S0_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1312614.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWKEDF"
     gene            7508..8458
                     /gene="rsmH"
                     /locus_tag="ACL3S0_001740"
     CDS             7508..8458
                     /gene="rsmH"
                     /locus_tag="ACL3S0_001740"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGR1312615.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMEMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLRPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            8470..8787
                     /gene="ftsL"
                     /locus_tag="ACL3S0_001741"
     CDS             8470..8787
                     /gene="ftsL"
                     /locus_tag="ACL3S0_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGR1312616.1"
                     /translation="MAERMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            8791..11043
                     /gene="pbp2X"
                     /locus_tag="ACL3S0_001742"
                     /gene_synonym="pbpX"
     CDS             8791..11043
                     /gene="pbp2X"
                     /locus_tag="ACL3S0_001742"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGR1312617.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQISQQTVDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEGITKDFVWRDILYQSNYE
                     PGSAMKVMTLAASIDNNTFPGGEYFNSSELKIADVTIRDWDVNEGLTGGGMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     NYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KSLEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKATAETFAKWLNIELEFEGSGTTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            11045..12025
                     /gene="mraY"
                     /locus_tag="ACL3S0_001743"
     CDS             11045..12025
                     /gene="mraY"
                     /locus_tag="ACL3S0_001743"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGR1312618.1"
                     /translation="MFISISAGIVTFLLTVVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLSSLLTLAILYLM"
     gene            12633..14738
                     /locus_tag="ACL3S0_001744"
                     /pseudo
     CDS             12633..14738
                     /locus_tag="ACL3S0_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063405.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
     gene            complement(15034..15516)
                     /locus_tag="ACL3S0_001745"
     CDS             complement(15034..15516)
                     /locus_tag="ACL3S0_001745"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGR1312619.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(15611..17095)
                     /locus_tag="ACL3S0_001746"
     CDS             complement(15611..17095)
                     /locus_tag="ACL3S0_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGR1312620.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            17248..18855
                     /locus_tag="ACL3S0_001747"
     CDS             17248..18855
                     /locus_tag="ACL3S0_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGR1312621.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPAIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTDQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            19020..19187
                     /locus_tag="ACL3S0_001748"
     CDS             19020..19187
                     /locus_tag="ACL3S0_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGR1312622.1"
                     /translation="MKKRILSAGLTFASALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(19180..19647)
                     /locus_tag="ACL3S0_001749"
                     /pseudo
     CDS             complement(19180..19647)
                     /locus_tag="ACL3S0_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5879 a         3573 c         4447 g         5748 t
ORIGIN      
        1 aaggaagatt tcccgacgcc agctaccttt gataatgtct atccaatcat ggataacacg
       61 gaatggacca atggtttctg gacaggagaa ctgtggttgg cttatgaata cagtcaacag
      121 gatgcattta aaaacatcgc tcataaaaat gttctttctt tcctggatcg tgtcaataag
      181 agagtagaat tggatcacca tgatctcggc ttcttgtaca caccgtcttg tatggctgaa
      241 tataagataa atggagatgg agaggctaga gaagcaacct tgaaagctgc agataagttg
      301 attgaacgct atcaagaaaa aggtggtttt attcaagctt ggggagactt gggcaagaaa
      361 gagcattacc gtttgattat cgactgcttg ctcaatatcc aactcttatt ctttgcttat
      421 caagaaacag gcgatcaaaa atactacgat attgcagaaa gtcatttcta tgcttcagct
      481 aataatgtaa tccgtgatga cgcttcgtcc ttccacacct tctattttga tcctgagaca
      541 ggtcaaccct ttaaaggtgt aacgagacaa gggtatagtg atgattcatg ctgggcacgt
      601 ggtcaatcat ggggagtcta tggtattcct ttgacttatc gtcacttaaa agacgagtcc
      661 tgctttgact tgtttaaggg tgtgaccaat tatttcttga atcgtctgcc aaaagatcat
      721 gtgtcctatt gggatttgat ttttaatgat ggtagtgatc aatcacgaga ttcttcagca
      781 acagctatcg ccgtctgtgg gattcatgaa atgctaaaac atcttccaga ggtggatgct
      841 gacaaagata tttataaaca tgctatgcat gccatgcttc gttccttgat cgaacattat
      901 gcaaatgatc aatttacccc tggtgggaca agtctcctcc acggtgtgta ctcatggcat
      961 tcaggtaaag gagtggatga aggcaatatc tggggtgact actattacct agaagccctt
     1021 atccgtttct acaaagactg gaacctatat tggtaggagg agaaatatga caatgccaaa
     1081 tattattatg acccgtatcg atgaacggtt gattcatggg caaggacaac tttgggtaaa
     1141 atacctaggt tgtaatacgg tcattgttgc caatgacgaa gtaagcacgg acaagatgca
     1201 acaaactctg atgaaaacag ttgtgccaga ctcagttgcc atgcgtttct tccctttgca
     1261 aaaggtgatt gatatcattc acaaggctaa tcctgctcaa acgatcttta tcgttgtaaa
     1321 ggatgtgaag gatgctttaa ccttggtaga aggtggtgtc cctatcaaag aaatcaatat
     1381 tgggaacatt cacaatgcta ctggtaaaga gcaagtgaca cgctccatct tcctgggtga
     1441 agaggacaag gcggccctca aggaattgag ccaaactcat caagtaacat ttaatacgaa
     1501 aacaactcca acaggaaatg atggagctgt tcaagtcaac attatggact atatttaaaa
     1561 gaggagatcg ttatgtcgat taatgtattt caagcgattt taattggatt atggacagct
     1621 ttctgtttta gtggaatgct gttaggaatt tacaccaata gatgtattgt tctgtcattt
     1681 ggtgtcggaa ttattctagg tgatctgcct actgctcttg caatgggagc tattggtgaa
     1741 ttggcttata tgggattcgg tgttggtgct ggaggtactg ttccaccaaa cccaatcgga
     1801 cctggtatct ttggtacctt gatggctatc actagtgctg gtaaagtcag tccagaagcg
     1861 gctcttgccc tctctactcc gattgctgtg gcgattcaat tcttacaaac tttcgcctac
     1921 actgtacgtg ctggtgcgcc tgaaacagcg atgaagcact tgaaaaacca taatttgaag
     1981 aaattcaagt tcactctaaa tgcaacaatt tggttgtttg cctttattgg atttaccttg
     2041 ggttgcttgg gtgccctttc aatggatacc ttgttgaaac tcgtagacta cattccaccg
     2101 gtattgctta caggtttgac agttgctggt aaaatgctcc cagctatcgg ttttgcgatg
     2161 atcttgtcag tgatggctaa gaaagagttg attccctttg tcttgttggg atatgtttgt
     2221 gcagcttatc taaacatccc aacaattggt attgcaattg taggtactat ctttgctttg
     2281 attgaatttt ataacaagcc aaaaacagcg gatcatgtgg tagaggagga agcacacgat
     2341 gactggatct aacaaattaa caaaacgtga ttatcttaaa acgtctttgc gggcattctt
     2401 ttgtcaaaat ggatttaact atagtaacta tcaagggttg ggatatgcca atgtgatgta
     2461 tcctgctttg aaaaaacact atggagagga tcaggaaggt ttctaccaag ccttggaaga
     2521 aaactgtgaa ttctataata ccaacccaca cttcctgcct tttattacca gcttgcatct
     2581 tgtaatgttg gaaaatggcc gtccggcaaa agaaacacgt agcatcaaga tggccttgat
     2641 gggaccattg gcaggtattg gggattctct ttctcaattc tgtttagctc cattgttctc
     2701 aaccatcgca gcttcgtttg ctcaagaagg cttggttgtc ggtccaatct tgttcttcct
     2761 tgcgatgaat acgattttaa cagcgattaa attgtcaact ggtctgtatg gatacaaact
     2821 aggaacaact gtgattgata aactaagcga acagatggca acgatttctc gtattgccaa
     2881 tattatcggt gtaaccgtaa ttgctggttt ggcagcgaca tctgttaaga ttatggtgcc
     2941 gattaccttt gctgcagggg aagttaaagc agacgctaaa caaagtatcg taagtattca
     3001 gggaatgctt gataaggttg ctccagctct tctaccagcc ctatttacac ttttagttta
     3061 ctacttgatc aaagaaaaga aatggacaac atataaactc gttattttaa cagttatcat
     3121 cggaattatc ggaagctggc ttaagattat agcttaatgg atacaacatt gttttatgga
     3181 atagtgattg tcttggcagt gagtcccctt ttactgtcaa gctttcattc tattcgtcag
     3241 caaaagttgc ttcgcaaaca gatggagcaa cgacaagagt atttagcttc tttaacatct
     3301 ggtgatgaag tgttgttatt gtctggaatt catggaaaaa tcatttctat ccaagatgac
     3361 ttggtctcct tgcagattgc aaaaggtgtg gtcatctatg tagaaaagga aagtgtaatg
     3421 ggaaagacaa aagaactgct ttttaagtag ttctttttct ggtaatagat aatgaaagaa
     3481 gaaagaagac aattttttga aagagtcgat ggaaaccaat gtcgtgatta tatcttgtcc
     3541 cactgttcaa aagactatga gaaagtcaag agttcccttg aacgcttgat agacaatcgt
     3601 tttatgtttg atagtccttg ggatatggag ccttgttcaa aaatccatca aatccagccg
     3661 atggtatggg atcaagtatt tgaagatgat ccagaatggt cttatatgct caatcgacaa
     3721 gaatatctct tgcagtttat gatagggtat ctggtagaag gagataaggg ctatatccaa
     3781 aagtgcaagt tctttctatt tgattggatt gagcaggtga gagaattttc tcctcaatcc
     3841 ttgatgacta gaaccttgga tacgggtatt cgttccttta cttggttgaa actactcttg
     3901 ctcctcttga aatttgactt gctagaggag aaagaactag agaaaatttt ggtcagtcta
     3961 gaaaagcaga ttgactttat gaaaagccac tatcgcgcca agtacaccct tagtaactgg
     4021 gggattttac aaacaattcc gatgcttgct atctattatt tcttttcaga taagatggac
     4081 ctagaagaag cttaccattt tgcttcagag gagttgaaac agcaaattga gacacagatt
     4141 ttaggagatg gaagccagtt tgaacagtcg attctctatc atgtagaggt ttataaagcc
     4201 ttgctggatt tgtgtctctt gcttccagac ttgcaagata gttaccgaga gttgctggaa
     4261 aagatggcga cctatattca aatgatgaca ggcttagatg gacgaacttt ggcttttggt
     4321 gatagcgatt ctacagaaac gacagaaatt ttgagcctgt ctgctgtggt tttgaacaag
     4381 gaagaccttc ttaacggtct ggatgttaaa gtcgatttgc ttagcctctt gttcctgggg
     4441 cgagaaaagg tcaagcgact gcaggaattt gaaaggagag cttggcagcc taagtccatg
     4501 atctttgaag actctggaca tgtctgcatt aaggatgaac atcgttatct atttttcaaa
     4561 aatggtccgc taggaagtgc ccatagccat agtgacgaga atagtttttg cttacagtat
     4621 caaggccaac ctattttcat agatgctggg cgttattctt atcgggagat atatgaacgt
     4681 tatctcttaa agagtgcttg gagtcattcg acctgcattg tagatgggaa agctccggaa
     4741 agaatcacgg gatcctggga atatgaatac tatcctcact ccctgttttg tcaccataaa
     4801 gaaagggagg gagtgcatta tattgagggg gcttattggt cagcagaacc tgatttgcct
     4861 tatcttcaca agagaaaaat cctcatgttg gtagaggatg tctggctctt ggtagatgac
     4921 atcaggtgtc aaggtcagca tgaggcgttg actcagttta tccttgacaa ggatgtgacc
     4981 tatcaagatg ggaaaatcaa tcagttgaga ctatggagtg aagttgattt tgatttggaa
     5041 gataccatca tttctcctaa atacaatgag cttgaaagaa gtagcaaact caccaagcgc
     5101 caattctttg agaatcagat gctggattat accatcattg cgcatgagag ttttgaaatt
     5161 atccgtcatt ctgtctacca gacagatgat cgtgaagtgg aaaatgctct ggcttttgaa
     5221 gtgaaaaatg acgaaacaga caagctgatt ctgttattaa gcgaggatat tggtgtaggt
     5281 gaaaaattgt gcctcgttga cggaacaaaa atgcgtggaa aatgtctagt atatgataaa
     5341 ataaatgaga gaatgattcg cttgcagtgc tagaaatagg cattttgaat agtgaatatg
     5401 ttataataag tattagtagg aggtgtttta gattggagaa gaaactgacc ataaaagaca
     5461 ttgcggaaat ggctcagacc tcgaaaacaa ccgtgtcatt ttacctaaac gggaaatatg
     5521 aaaaaatgtc ccaagagaca cgtgaaaaga ttgaaaaagt tattcatgaa acaaattaca
     5581 aaccgagcat tgttgcgcgt agcttaaact ccaaacgaac aaaattaatc ggtgttttga
     5641 tcggtgatat taccaacagt ttctcaaacc aaattgttaa gggaattgag gatatcgcca
     5701 gccagaatgg ctaccaggta atgataggaa atagtaatta cagccaagag agtgaggacc
     5761 ggtatattga aagcatgctt ctcttgggag tagacggctt tattattcag ccgacctcta
     5821 atttccgaaa atattctcgt atcatcgatg agaaaaagaa gaaaatggtc ttttttgata
     5881 gtcagctcta tgaacaccgg actagctggg ttaaaaccaa taactatgat gccgtttatg
     5941 acatgaccca gtcctgtatc gaaaaaggtt atgaacattt tctcttgatt acagcggata
     6001 cgagtcgttt gagtactcgg attgagcggg caagtggttt tgtggatgct ttaacagatg
     6061 ctaatatgcg tcacgccagt ctaaccattg aagataagca tacgaatttg gaacaaatta
     6121 aggaattttt acaaaaagaa atcgatcccg atgaaaaaac tctggtattt atccctaact
     6181 gttgggccct acctctagtc tttaccgtta tcaaagagtt gaattataac ttgccacaag
     6241 ttgggttgat tggttttgac aatacggagt ggacttgctt ttcttctcca agtgtttcga
     6301 cgctggttca gccctccttt gaggaaggac aacaggctac aaagattttg attgatcaga
     6361 ttgaaggccg caatcaagaa gaaaggcaac aagtcttgga ttgtagtgtg aattggaaag
     6421 agtcgacttt ctaaaatgaa ggaaaatgac ttgcaatttc tgttaagaaa taaaataatc
     6481 ccacctagaa caagctaggt gggattattt gcctatgaaa tgagaaatta tgggagcaag
     6541 ctcctaaatc aactgttttt gatctacttc tttaactact tgataaaagt tatagaagta
     6601 ggccaaactt gaaatgatgg ttacgactag gaatattgaa aatttccatt ggacagggtt
     6661 ggttaaaagt tgtggaaagg atatgaggag aaagaagagg gctgcgttga ggacaggtat
     6721 ccgttttgat tgtattttct caagtccttt attgagcgca ggaagaaaga ggagtaggag
     6781 tagtaaaact gtatgagaaa cagctcctga aataagggcg aagaaaagga aaatactgat
     6841 aaaaacatga atgatcagta gtctagctag tgatttcata aggcacctcc taatcctggt
     6901 cttttttagc tcttgcaata cgaagtgagt cgacaatatg tatcatcact ccgaaaaaga
     6961 aagctcccag tatagtttta aaaatatgtt ttgtatttag aagagaactg ataaaatttg
     7021 gattttcact tgttagggta tcaatgagtg gaattataaa aaatatcact gttccataaa
     7081 tcgaacctgc tttcagacca ggataacgta actgtttctt ttcttttttc atgagtttgc
     7141 tcctttttta aaaatcttcc ttccaaaaga gactgttgag gtcagtttgg aggctgcgag
     7201 cgagattgag acagagttcc agagttggat tgtacttgtc gttttcaatc atattgatgg
     7261 tctgtctcga gacaccgata tccttggcga gctcgagctg ggaaatgccc agttccttgc
     7321 gaaattcttt cacacgattc atctggtctc ctttctgatt tgtgtcgtat atatttgact
     7381 ttattatagt cttttaaaca taaagtgtca agtatttttg acatattttt tgaagaaata
     7441 gtagtctcct tgtcctattt gtctgacaag tgcaagctgg tcggatttgt ggtaaaatag
     7501 ataagatatg acaaaagaat ttcatcatgt aacggtctta ctccacgaaa cgattgatat
     7561 gcttgacgta aaacctgacg gtatctacgt tgatgcgact ttgggtggag caggccatag
     7621 cgagtattta ttaagtaaat taagtgaaaa aggccatctc tatgcctttg accaggatca
     7681 gaatgccatt gacaatgcgc aaaaacgctt ggcaccttac attgagaagg gaatggtgac
     7741 ctttatcaag gacaacttcc gtcatttaca ggcacgtttg cgcgaagctg gtgttcagga
     7801 aattgatgga atttgttatg acttgggagt gtctagtcct caattagacc agcgtgagcg
     7861 tggtttttct tataaaaagg atgcgccact ggacatgcgg atgaatcagg atgctagtct
     7921 gacagcctat gaagtggtga acaattatga ctatcatgac ttggttcgta ttttcttcaa
     7981 gtatggagag gacaaattct ctaaacagat tgcgcgtaag attgaacaag ctcgggaagt
     8041 caagccaatc gagactacga ctgaattggc agaaattatc aagtcggcca aacctgccaa
     8101 ggagctcaag aagaagggcc atcctgccaa acagatcttc caggctattc ggattgaagt
     8161 taacgatgag ctgggggcgg cagatgagtc tatccagcag gctatggaga tgttggcttt
     8221 ggatggtaga atttcagtga ttacctttca ttccttggaa gaccgcttga ccaaacagtt
     8281 attcaaggaa gcttcaacgg ttgaagttcc caaaggtttg cctttcatcc cagatgatct
     8341 caggcccaag atggaattgg tatcccgtaa gccaatcttg ccaagtgcag aagaattaga
     8401 agccaataac cgctcgcact cagccaagtt gcgcgtggcc agaaaaattc acaagtaaga
     8461 ggaaaaaaga tggcagaaag aatggaaaaa acaggtcaaa tactacagat gcaacttaaa
     8521 cggttttcgc gtgtggaaaa agctttttac ttttccattg ctgtaaccac tcttattgta
     8581 gcaattagta ttatttttat gcagaccaag cttttgcaag tacagaatga tttgacaaaa
     8641 atcaatgcgc agatagagga aaagaagacc gaattggacg atgccaagca agaggtcaat
     8701 gaactattac gtgcagaacg tttgaaagaa attgccaatt cacacgattt gcaattaaac
     8761 aatgaaaata ttcgaatagc ggagtaagat atgaagtgga caaaaagagt aatccgttat
     8821 gcgacgaaaa atcggaaatc gccggctgaa aacagacgca gagttggaaa aagtctgagt
     8881 ttattatctg tctttgtttt tgccgttttt ttagtcaatt ttgcggtcat tattgggacg
     8941 ggcactcgct ttggaacaga tttagcgaag gaagctaaga aggttcatca aaccacccgt
     9001 acagttcctg ccaaacgtgg gactatttat gaccgaaatg gagtcccgat tgctgaagat
     9061 gcgacatctt ataatgtcta tgcggtcatt gatgagaact ataagtcagc aacgggtaag
     9121 attctttacg tagaaaaaac acaatttaac aaggttgcag aggtctttca taagtatctg
     9181 gacatggaag aatcctatgt aagagagcaa ctctcgcaac ctaatctcaa gcaagtttcc
     9241 tttggagcaa agggcaatgg gattacctat gccaatatga tgtctatcaa aaaagagttg
     9301 gaaactgcag aggtcaaggg gattgatttt acaaccagtc ccaatcgtag ttacccaaac
     9361 ggacaatttg cttctagttt tatcggacta gctcagctcc atgaaaatga agatggcagc
     9421 aagagcttgc tgggaacctc tggaatggag agttccttga acagtattct tgcagggaca
     9481 gacggcatta ttacctatga aaaggatcgt ctgggaaata ttgtccccgg aacagaacaa
     9541 atttcccaac aaacggtgga tggtaaggat gtttacacaa ccatttccag ccccctccag
     9601 tcctttatgg aaacccagat ggatgctttt caagagaagg taaaaggtaa gtacatgacc
     9661 gcgaccttgg tcagtgcaaa gactggtgaa atccttgcta ccacccaacg accgaccttt
     9721 aatgcagata ctaaagaagg aatcactaag gactttgttt ggcgtgatat cctttatcaa
     9781 agtaactatg aaccagggtc agccatgaag gttatgacgt tagctgcttc tattgataac
     9841 aataccttcc caggtggaga atatttcaat agcagtgaat taaaaatagc ggatgtgacg
     9901 atccgagatt gggacgttaa tgaaggtttg accggcggtg gtatgatgac cttttctcaa
     9961 ggatttgctc actcaagtaa cgttgggatg accctccttg agcaaaagat gggagatgct
    10021 acctggcttg attatcttaa tcgctttaaa tttggtgttc cgacccgttt cggtttgacg
    10081 gatgagtatg ctggtcagct tcctgcggat aatattgtca acattgcgca aagctcattt
    10141 ggacaaggga tttcagtgac ccagacgcaa atgattcgtg cctttaccgc tattgctaat
    10201 gacggtgtca tgctggagcc taaatttatt agtgccattt atgatccaaa tgatcaaact
    10261 gctcggaaat ctcaaaaaga aattgtggga aatcctgttt ctaaagatgc agctagtcta
    10321 actcggacta acatggtttt ggtagggacg gatccggttt atggaaccat gtataaccac
    10381 agcacaggca agccaactgt aactgttcct gggcaaaatg tagccctcaa gtctggtacg
    10441 gctcagattg ctgacgagaa aaatggtggt tatctagtcg ggttaactaa ctatattttt
    10501 tcggctgtat cgatgagtcc ggctgaaaat cctgatttta tcttgtatgt gacggtccaa
    10561 caacctgaac attattcagg tattcagttg ggagaatttg ccaatcctat cttggagcgg
    10621 gcttcagcta tgaaagactc tctcaatctt caaacaacag ctaaatcttt ggagcaagta
    10681 agtcaacaaa gtccttatcc tatgcctagt gtcaaggata tttcacctgg tgatttagca
    10741 gaagaattgc gtcgcaatct tgtacaacct attgttgtgg gaacaggaac gaagattaaa
    10801 aacagttctg ctgaagaagg gaagaatctt gccccgaatc agcaagtcct gatcttatct
    10861 gataaagcag aggaagttcc agacatgtat ggttggacaa aggcgactgc tgagaccttt
    10921 gctaagtggc tcaatataga acttgaattt gaaggttcgg gcactactgt gcagaagcaa
    10981 gatgttcgtg ctaatacagc tatcaaggac attaaaaaaa ttacattaac tttaggagac
    11041 taatatgttt atttccatca gtgctggaat tgtgacattt ttactaactg tagtaggaat
    11101 tccggccttt atccaatttt atagaaaggc gcaaattaca ggccagcaga tgcatgagga
    11161 tgtcaaacag catcaggcaa aagctgggac tcctacaatg ggaggtttgg ttttcttaat
    11221 tacttctgtt ttggttgctt tcttttttgc cctatttagt agccaattca gcaataatgt
    11281 gggaatgatt ttgttcatct tggtcttgta tggcttggtc ggatttttag atgactttct
    11341 caaggtcttt cgtaaaatca atgaggggct taatcctaag caaaaattag ctcttcagct
    11401 tctaggtgga gttatcttct atcttttcta tgagcgcggt ggcgatatcc tgtctgtctt
    11461 tggttatcca gttcatttgg gatttttcta tattttcttc gctcttttct ggctagtcgg
    11521 tttttcaaac gcagtaaact tgacagacgg tgttgacggt ttagctagta tttccgttgt
    11581 gattagtttg tctgcctatg gagttattgc ctatgtgcaa ggtcagatgg atattcttct
    11641 agtgattctt gccatgattg gtggtttgct cggtttcttc atctttaacc ataagcctgc
    11701 caaggtcttt atgggtgatg tgggaagttt ggccctaggt gggatgctgg cagctatctc
    11761 tatggctctc caccaagaat ggactctctt gattatcgga attgtatatg tttttgaaac
    11821 aacttctgtt atgatgcaag tcagttattt caaactgaca ggtggtaaac gtattttccg
    11881 tatgacgcct gtacatcacc attttgagct tgggggattg tctggtaaag gaaatccttg
    11941 gagcgagtgg aaggttgact tcttcttttg gggagtggga cttctatcaa gtctcctgac
    12001 cctagcaatt ttgtatttaa tgtaagaatg gcaccctgat gtttcagggt gtttttgtat
    12061 ttaaatacac aatgaaaatc aaagaacaaa ctagaaagct aactttaggc tgctcaaaat
    12121 atagtagatt gaaactagaa tagtacacat ctgcttctaa aatattgtta gaaatcgatt
    12181 tgactgtcct gatcgatttg tcctgttctt atttcatttt aatatacagt tttgagatgg
    12241 ctgatagaac tgacgaagtc agctcaaaac acggttttga ggttgtagat aaggagaagc
    12301 tgatgtggtt tgaagaggtt ttcgaagagt gtaaaaaata ttggtcagtt aaagtcaaaa
    12361 ctcttgacct tttctgacca atgtagtata ttatgaacgt aaggtaaatg aaagccttac
    12421 tagaacactt atttaaagta aaatagaaag aggtgggtct atgtttcatc tagcaatctt
    12481 cagaggtaaa gatagtctac tcctgcttga aaaagaaaaa ccagaaatag tacgtagggt
    12541 agcggtttag ctagtctaaa ttttttaaaa caatggtcaa agatagtcaa tatcagtaat
    12601 cataactaag taaacaaaaa gaggtaaaga atatgaataa caactttaat aattttaata
    12661 acatggatga tttatttaac caattgatgg gtggtatgcg aggatatagt tctgaaaatc
    12721 gccgttactt aattaatgga cgcgaagtca cacctgagga atttgctcac tatcgtgcga
    12781 ctggtcaatt accaggaaat gcagaaactg atgtgtaaat gccacaacag gcatcaggta
    12841 tgaaacaaga cggtgtcctt gcaaaactag gtcgaaactt gacagcagaa gcgcgtgagg
    12901 gcaagttgga tcctgttatc ggacgaaaca aggaaattca agaaacatct gaaatcctct
    12961 cacgccgcac caagaacaat cctgttttgg tcggagatgc aggtgttggt aagacagcag
    13021 ttgtcgaagg tctagcgcaa gccattgtga acggagatgt tcctgctgct atcaagaaca
    13081 aggaaattat ttctattgat atctcaggtc ttgaggctgg tactcaatac cgtggtagct
    13141 ttgaagaaaa tgtccaaaac ttagtcaatg aagtgaaaga agcagggaat attatcctct
    13201 tctttgatga aattcaccaa attcttggtg ctggtagcac tggtggagac agtggttcta
    13261 aagggcttgc ggatattctc aagccagctc tctctcgtgg agaattgaca gtgattgggg
    13321 caacaactca agacgaatac cgtaacacca tcttgaagaa tgctgctctt gctcgtcgtt
    13381 tcaacgaagt gaaggtcaat gctccttcgg cagagaatac ttttaaaatt cttcaaggaa
    13441 ttcgtgacct ctatcaacaa caccacaatg tcatcttgcc agacgaagtc ttgaaagcag
    13501 cggtggatta ttctgttcaa tacattcctc aacgtagctt gccagataag gctattgacc
    13561 ttgtcgatgt aacggctgct cacttggcgg ctcaacatcc agtaacagat gtgcatgctg
    13621 ttgaacgaga aatcgaaacg gaaaaagaca agcaagaaaa agcagttgaa gcagaagatt
    13681 ttgaagcagc tctaaactat aaaacacgca ttgcagaatt ggaaaagaaa atcgaaaacc
    13741 acacagaaga tatgaaagtg actgcaagtg tcaacgatgt ggctgaatct gtggaacgaa
    13801 tgacaggtat cccagtatcg caaatgggag cttcagatat cgaacgtttg aaagatatgg
    13861 ctcatcgctt gcaagacaag gtgattggtc aagataaggc cgtagaagct gtagctcgtg
    13921 ctatccgtcg taaccgtgct ggttttgatg aaggaaatcg cccaatcggc agcttcctct
    13981 ttgtagggtc tactggggtt ggtaagacgg agcttgctaa gcaattggca ctcgatatgt
    14041 ttggaaccca ggatgcgatt atccgtttgg atatgtctga atacagtgac cgcacagctg
    14101 tttctaagct aattggtaca acagcaggct atgtgggtta tgatgacaat agcaatacct
    14161 taacagaacg tgttcgtcgc aatccatact ctatcattct cttggatgaa attgaaaagg
    14221 ctgaccctca agttattacc cttctcctcc aagttctaga tgatggtcgt ttgacagatg
    14281 gtcaaggaaa tacagtaaac ttcaagaaca ctgtcattat tgcgacctca aatgctggat
    14341 ttggctatga agccaacttg acagaagatg cggataaacc agaattgatg gaccgtttga
    14401 aacccttctt ccgtccagaa ttcctcaacc gctttaatgc agtcatcgag ttctcacact
    14461 tgactaagga agatctttct aagattgtag atttgatgtt ggctgaagtt aaccaaacct
    14521 tggctaagaa agacattgac ttggtagtta gtcaagcggc taaagattat atcatagaag
    14581 aaggttacga cgaagtcatg ggggttcgtc ctctccgtcg cgtggttgaa caagaaattc
    14641 gtgataaggt gacagacttc cacttggatc atttagatgc taaacatctg gaagcagata
    14701 tggaagatgg cgttttggtt attcgtgaga aagtctaaga cagaattttg aggataaaaa
    14761 agaaggagcc agctgaaaaa aactggttcc ttttgaggta tgacgggcat gtcgtatagt
    14821 agaagtgtat tattctagtt tcaatttact atagtagctc agaagtcggt acttaaacgt
    14881 gctatatcaa aaccagtcct tgaaaaacgt ggactggttt cgtgtttgga ttattacctt
    14941 gaacgacatg cgttaaaagt tagttgaaca gccgtatgcc gaacggcacg tacggtggtg
    15001 tgagaggggc tagagattat cccctactcg attttaaatc acatgacgtt caaaggcatc
    15061 atctgaaatc ccttgttcca agatgagttt tgcccattct ttagcagaga agaggctgtg
    15121 gtccttgtag tttccgcaag attcgatggt tgtccctggg acatcttccc aagtagtagt
    15181 ttcagcgatt tccttgagcg aatccttgat aacagctgcg attttagcac tggtgtgacg
    15241 tccccacata atcatgtgga agcctgtgcg gcaaccaaat ggtgaacagt caatcatgcc
    15301 gtcaatgcgg gtacggatga gtttggctaa gaggtgctcg atagtgtgaa ggccggcagt
    15361 agggatagag tcttcgtttg gttgcaccaa gcgaatatca taattggaga tgatgtctcc
    15421 ttttggtcct gtttcttccc caatcaagcg aacatagggt gctttgacaa tggtgtggtc
    15481 aagttcaaaa ctttcgacaa taacttcttt tgacatggta aatcctttca gttttcttct
    15541 ctcattatat cataaaggtt gctcctgaga cagagagaaa acctctccga ggctggagag
    15601 gttgaaatct ttacttacga tataagcggt cgtattggta gtatgggtca aaggttacgt
    15661 tgatacccag tttacgaagg acattcttgt cttcatcagt caagatgatg gttgagtggg
    15721 cttcgcttcc tttgaggttg ccgagttctt ccatagcgcg ggcagcatca ggattttctg
    15781 tagctgtgat agcaagtgca atcaggattt catttgaatg aaggcgtgga ttgcggctac
    15841 cgagatgatc gattttaaga ccttggattg gcttaacaac ttcaggctcg attagtttta
    15901 cttctttagc gatgtcagct gattttttga tggcattgat caaggcagcg gctgtagggc
    15961 caaagagttc tgagttctta ccagtgatga tttccccatt tggcaattca aaggctaggg
    16021 ctggtccacc agtttcttct gctttttggc gcgcaacgac agcaacctta cggtctgcag
    16081 gtgtgatacc gaggtcgttc atgagcaact caattttctt gacggcagct tcgccaactt
    16141 tttcagcttt gaagtcaaga actgtttgat agtaacggcg gatgatttct tgtttagaag
    16201 cttcgacagc agcctcgtca tctgtaatag cgaaaccaac catgttgaca cccatatctg
    16261 tcggtgaagc gtatggtgat tttccgagaa tacgttccaa catgcgcttg agcactggga
    16321 agatttcgat atcacggttg tagttgacag tggtttctcc ataggtttga agatggaagg
    16381 ggtcaatcat gttgacatca tcaaggtcag ctgtggcagc ttcataagcc aagttaactg
    16441 gatgatgaag gggaagattc caaacaggga aggtttcaaa tttagcgtag ccagatttga
    16501 tgccattgat ttggtcgtgg tacatattgg acatacacgt tgccaatttt ccagaaccgg
    16561 gtccaggagc ggttacgaca atcaagttgc gactggtttt gatgtagtcg tttttgccca
    16621 tgccttctgg ggaaatgatg tgatccatat ccgtcggata tcctttgatt ggataatgaa
    16681 gataagaatc aattccgttt ttctcaagtt ggttgcggaa ggcatctgca gcgggttggc
    16741 cagcgtattg tgtaatgaca acggaaccaa caaaaatccc taattcattg aatttgtcaa
    16801 tcaaacgaag aacttcttgg tcataagaaa tgcccaagtc gccacgtgct ttggaatgtt
    16861 caatgttgct agcattaatg gcaatcacaa cctcaacctg ctctttcaat tcttgcaaga
    16921 gcttgatttt gttgtcaggt tcataaccag gaaggacacg agcagcgtgg aaatcttcta
    16981 acattttgcc accaaactct aggtaaagct tgccgtcaaa ttggttaatg cgctctaaga
    17041 tgtggtcgcg ttgtaaattc aaatactgtt cagaactaaa agcttgtttt ttcatttttt
    17101 tacctctgga ctctattata ataaaaaatt ggaagttagg aaactacgga gctaaaaaat
    17161 aaattaaaaa gattaagcaa acgcttgcac aaaattttaa aaagtgctat catatactat
    17221 agattattaa aataatgagg taaacagatg caagaaaaat ggtggcacaa tgccgtagtc
    17281 tatcaagtct atccaaagag ttttatggat agtaatggag atggagttgg tgatttgcca
    17341 ggtattacca gtaagttgga ctatctagcc aagctaggaa tcacagcaat ttggctttct
    17401 cccgtttatg acagccctat ggatgataat ggctatgata ttgctgatta tcaagcgatt
    17461 gcggctattt ttggaaccat ggaggacatg gatcagctga ttgcagaagc taagaagcgt
    17521 gacattcgta tcatcatgga cttggtggtt aatcatacct cagatgaaca tgcttggttt
    17581 gtcgaagcct gtgaaaatac tgacagccct gagcgagact actatatctg gcgcgatgaa
    17641 cccaatgacc tagattctat ctttagtggg tctgcttggg aatacgatga aaagtcaggt
    17701 caatactatc tccacttttt cagcaagaaa cagccggatc tcaactggga aaatgaaaaa
    17761 cttcgccaga aaatttatga gatgatgaac ttctggattg ataaaggtat tggtggtttc
    17821 cgtatggatg ttattgacat gattggcaaa attcctgacg agaaggtagt caataatggt
    17881 cctatgctcc atccctatct caaggaaatg aatcaggcga cctttggaga taaggatctc
    17941 ttgacagtag gggagacttg gggagcaacg ccagcgattg ccaagcttta ctctgatcca
    18001 aaggggcaag aattgtctat ggtcttccag tttgaacata tcggtcttca gtatcaggaa
    18061 ggtcagccta aatggcacta tcaaaaagag ctgaatatcg ctaagttaaa agaaatcttc
    18121 aacaaatggc agacagagtt aggagttgag gacggttgga attccctctt ctggaacaat
    18181 catgacctcc ctcgtatcgt ctcaatctgg ggaaatgacc aagaataccg cgaaaaatct
    18241 gccaaagcct ttgcaatctt gcttcatctt atgagaggaa ctccttatat ctaccaaggt
    18301 gaggagattg ggatgaccaa ctatccgttt gaaacactgg atcaagtaga agatattgaa
    18361 tctctcaact atgcgcgtga ggctcttgaa aaaggtgttc cgattgaaga aatcatggac
    18421 agtatccgtg ttattggacg tgacaatgcc cgtaccccta tgcaatggga cgagagcaaa
    18481 aacgctggtt tctcaacaga tcaaccttgg ttggcagtta atccaaatta cgagatgatc
    18541 aacgtccaag aagcgctggc aaatccagat tctattttct atacctatca gaaactggtc
    18601 caaattcgca aggagaatag ttggctaatt cgagctgact ttgaattgct tgatacggct
    18661 gataaggtct ttgcttatat acgtaaggat ggcgaccgtc gcttcctagt tgtggctaac
    18721 ttgtccaatg aagagcaaga cttgacagta gaaggaaaag tcaaatctgt cttgattgaa
    18781 aacaccctag ctcaagaagt ctttgaaaaa caaatcttag ttccatggga tgctttctgt
    18841 gtggaattac tataaatatt ttttgcagaa aaatttaaaa ttgaaatcat ataaaaacaa
    18901 gggaggactg tataaaaggc ggaaatcctt tgttttttat aaccaaggtt tataaacttt
    18961 cattctcgaa attcaattaa ctttacaaat tcccactatt aaggagaaag aagacgaaca
    19021 taaagaagcg tatccttagt gcaggcctga cttttgcatc tgctttgctt ttagctgctt
    19081 gcgaccaatc aggttcagat acaaaaactt actcatcaac ctttagtgga aatccaacta
    19141 catttaacta tctattagac tattacgctg ataatatagt caattgaaac aagagaaaga
    19201 caaaagagcc tcgtaaaagg tattgcaact tggtaatacc tttttgaggt gctttttgat
    19261 atgagcccat gttttctcaa taggattgta ctcaggtgag tagggaggaa gaggtaaaag
    19321 tttatgccca aactcttcgc ataaaagttc tagcttcccc attctatgga atcttgcatt
    19381 atccataata ataaccgatg gtgtggttaa tgttggtaag aaaaacttct gaaaccaagc
    19441 ttcaaaaaag tcgctcgtca tcgtctcttc gtaagtcatt ggaacgatta actcaccatt
    19501 tgttagacct gcaaccaaag aaatcctctg atatcttctt ccagatactt tgcctcttct
    19561 taactgacct tttaatgagc gaccatattc tcgataaaaa taagtatcga atcctgtttc
    19621 atcaatctaa acaggtgcta ggtgctt
//
LOCUS       DBEJZV010000038        19063 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.38, whole genome shotgun sequence.
ACCESSION   DBEJZV010000038 DBEJZV010000000
VERSION     DBEJZV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19063
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.38"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(227..640)
                     /gene="ndk"
                     /locus_tag="ACL3S0_001750"
     CDS             complement(227..640)
                     /gene="ndk"
                     /locus_tag="ACL3S0_001750"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGR1312623.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEESLPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(751..4428)
                     /gene="rpoC"
                     /locus_tag="ACL3S0_001751"
     CDS             complement(751..4428)
                     /gene="rpoC"
                     /locus_tag="ACL3S0_001751"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGR1312624.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYIHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLLYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(4461..8072)
                     /gene="rpoB"
                     /locus_tag="ACL3S0_001752"
     CDS             complement(4461..8072)
                     /gene="rpoB"
                     /locus_tag="ACL3S0_001752"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR1312625.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            8488..8558
                     /locus_tag="ACL3S0_001753"
     tRNA            8488..8558
                     /locus_tag="ACL3S0_001753"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8520..8522,aa:Cys,seq:gca)
     gene            complement(8756..10087)
                     /locus_tag="ACL3S0_001754"
     CDS             complement(8756..10087)
                     /locus_tag="ACL3S0_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGR1312626.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(10378..11202)
                     /gene="endA"
                     /locus_tag="ACL3S0_001755"
     CDS             complement(10378..11202)
                     /gene="endA"
                     /locus_tag="ACL3S0_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGR1312627.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(11241..11429)
                     /locus_tag="ACL3S0_001756"
     CDS             complement(11241..11429)
                     /locus_tag="ACL3S0_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR1312628.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(11422..12705)
                     /gene="murA"
                     /locus_tag="ACL3S0_001757"
     CDS             complement(11422..12705)
                     /gene="murA"
                     /locus_tag="ACL3S0_001757"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR1312629.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKVSQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(12729..12959)
                     /locus_tag="ACL3S0_001758"
     CDS             complement(12729..12959)
                     /locus_tag="ACL3S0_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGR1312630.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(13017..14054)
                     /locus_tag="ACL3S0_001759"
     CDS             complement(13017..14054)
                     /locus_tag="ACL3S0_001759"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGR1312631.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(14038..14526)
                     /gene="coaD"
                     /locus_tag="ACL3S0_001760"
     CDS             complement(14038..14526)
                     /gene="coaD"
                     /locus_tag="ACL3S0_001760"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGR1312632.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(14516..15055)
                     /gene="rsmD"
                     /locus_tag="ACL3S0_001761"
     CDS             complement(14516..15055)
                     /gene="rsmD"
                     /locus_tag="ACL3S0_001761"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGR1312633.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(15120..16112)
                     /gene="asnA"
                     /locus_tag="ACL3S0_001762"
     CDS             complement(15120..16112)
                     /gene="asnA"
                     /locus_tag="ACL3S0_001762"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGR1312634.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDCLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(16224..16907)
                     /locus_tag="ACL3S0_001763"
     CDS             complement(16224..16907)
                     /locus_tag="ACL3S0_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HGR1312635.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(16963..17703)
                     /locus_tag="ACL3S0_001764"
     CDS             complement(16963..17703)
                     /locus_tag="ACL3S0_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGR1312636.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFYLS"
     gene            17737..18015
                     /locus_tag="ACL3S0_001765"
     CDS             17737..18015
                     /locus_tag="ACL3S0_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGR1312637.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYYDFKIAN"
     gene            18093..19019
                     /gene="yidC"
                     /locus_tag="ACL3S0_001766"
     CDS             18093..19019
                     /gene="yidC"
                     /locus_tag="ACL3S0_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR1312638.1"
                     /translation="MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
BASE COUNT         5378 a         4471 c         3724 g         5490 t
ORIGIN      
        1 tgtatcgcgt ttggagtttt tttggtataa ccttcgacgc gcacccgcat agcgggtgtt
       61 tttttgtctc gcacctaacg gagcgagacg aactaatagt cacttaatca aaaaacgcac
      121 catatcaaaa actaaaaagt ttgatatcat gcgtcatgtc ttaaactaat tgactatact
      181 ttctattcaa atgagctttt aaccaattga ttgagccaat ccactcttaa aaccaaagag
      241 caatttctcg cttagctgac tcttctgaat ctgaaccatg tacaacattt tggataacct
      301 cattttctcc agcagctttt gcaaagtcac ctcgaatagt gcctggtaaa gattcttctg
      361 gacgagttgc acccatcatg gtccgccaag tttcgattac tttgggacca gaaatgacac
      421 ccacaagaac tggacctgaa gtcatgaatt cacgaatcgg taggtaaaaa ctctgaccaa
      481 ccaagtcctg atagtgctgg tcaatcaact cttctgaaac ctgtgaacga aactccaatt
      541 tttcgattgt aaatccacgt tgttcgatgc gctttaacac ttcacccact agccctcttt
      601 ttacaccatc tggtttgatg ataaagaatg tttgttccat acccgtctcc tttgtcagct
      661 tctttctttt attttaccac atttcgtgga aaaatggaga aagttttcag aagagagaat
      721 gagagaaccc gagggttctc tcattctctc ttattctact gtttcttcca cagtttcaac
      781 ggcagtatcc acaactactt ctgttgtttc ttcatttcct tcttcctcta ctggaggatt
      841 aaggtattct tcttcgttga cagcatgtgg ttcaaggtta cggtaacggg ccataccagt
      901 accagctggg atgatcttac cgatgataac attttcttta agtccaagga gatggtcttt
      961 cttaccacgg atagctgcgt cagtaaggac acgagttgtt tcttggaagg aagctgctga
     1021 caagaaactg tttgtttcaa gtgaggcttt ggtaattccc ataaggactg ggcgacctgt
     1081 cgctggaact ccacctgcga taaggacatc tttgttggca tctgtaaagt cattgatatc
     1141 catgagggta cccatgagaa gatctgtatc acctggatcc atgacacgga ctttacggat
     1201 catttgacga accattacct cgatgtgttt gtcaccgatt tctacccctt ggctacggta
     1261 aactttttgt acttcaccga gaaggtacgt ttcaactgac aagacatcac gaactgcaag
     1321 gagacgtttt ggttggatag aaccttctgt cagagcagca ccacgcgcta cttggccccc
     1381 aacttcgaca cgcatacgag ctgtaaatgg aacgacatat tcaccttcgc cagtttcacc
     1441 cttaacaaag actttcttgg tacgagttga tgcatcttct tcgatagcag taacttgtcc
     1501 tttaacctct gtgataaccg cttccccttt aggattacgg gcttcaaaga tttcttggac
     1561 acgaggaaga ccctgagtga tatcggtatt tgaggcaacc ccacctgtgt ggaaggtacg
     1621 cattgtaagc tgtgtaccag gttccccgat agattgggca gcaattgtac caactgcttc
     1681 accaacttca accgcatcac cagtcgccaa gttgataccg taacagtgac ggcagacacc
     1741 gtgacgagtg ttacatgtaa atacagaacg gatagtcact tcttccacac cagcattgac
     1801 aatttcacgc gccttgtctt ctgtaatcaa ttcatttgga ccaataatca ctgcaccagt
     1861 ttctggatgt ttaacagttt tcttagtgta acgaccgttg agacgctctt cgagagactc
     1921 gatcatctct tttccttctg cgatagaacg gatcaagaga ccacggtcag ttccacagtc
     1981 gtcctcacgg atgataacgt cttgggcaac gtcgaccaaa cgacgagtca agtaacctga
     2041 gtcggctgtc ttaagggccg tatcggtcat acctttacga gcaccgtgag ttgagaagaa
     2101 catttccaat accgacaaac cttcgcggaa gtttgaaagg attggcaatt ccatgatacg
     2161 tccattcgga gcagccatca gaccacgcat accggcaagc tgtgagaagt ttgagatgtt
     2221 accacgggct ccagagtcca tcatcataac gattgggttc ttaggatctt ggttagcaat
     2281 caagcgtttc tcaagttttt cacgggcagc acgccattca gctgtaacag cattgtaacg
     2341 ctcgtcgtct gtgatcatac cacgacggaa ttgtttggtg atttgttcga cacgtttgtg
     2401 tgattcttca atgatttcag tcttgtcatc aacgactggg atatcggcaa tacccactgt
     2461 caatcctgca agagttgagt ggtggtaacc gaggttcttc atgcggtcaa gtagggcaga
     2521 agtttctgtc gtacggaaac gtttgaagat ttcagcgatg atatttccaa ggtttttctt
     2581 cttgaatgga gggttgagct caagattgct gatagcttcc ttgatatctc caccaagtgg
     2641 caagaagtat ttagctggaa caccttctgt caagttggca ttgtttggtt cttgcaagta
     2701 tagtagcccc tctggcatga tatcgttgaa gagaatttta ccaactgttg taagcaagac
     2761 cttatgtctt tgctcttctg tccaaggctt gttgaggctg tctgttgcga taccaacacg
     2821 tgagtggagg tgaatataac cattgcggta agccataacc gcttcgtcac ggtctttgaa
     2881 gaccattcct tcaccttcgc gaccagcttc ttccatggtc aagtagtagt tacccaaaac
     2941 catgtcctga gatggagtaa ctaccggttt cccatctttc gggttcaaga tgtgctcagc
     3001 agctagcatg aggatacgag cttctgcttg tgcttcttct gaaagtggta cgtggatggc
     3061 catttggtcc ccgtcaaagt cagcattgta ggcttcacag acaagtgggt gcaagcgaag
     3121 agccttacca tcaatcaaga ctggctcgaa ggcttggata cccaaacggt gaagggtcgg
     3181 tgcgcggttc aaaagcactg ggtgttcttt aatcacttct tcaaggatat cccagatacg
     3241 ctcatctccg cgttccacca agcgtttagc tgctttgacg ttttgcacga tatcacgggc
     3301 aacgatttca cgcatgacaa atggtttaaa gagttcaatc gccatttcac gcggcacacc
     3361 acattggtac atcttaagag ttggaccaac ggcgataacg gaacgtcctg agaagtcaac
     3421 acgtttaccg agcaagtttt gacggaagcg tccctgttta cctttaagca tgtggctcaa
     3481 tgatttcaat ggacggctac ctggtcctgt gattggacga ccacgacgac cattgtcaat
     3541 caaagcgtca actgcttctt gaagcatacg cttctcattt tgaacgatga tacctggggc
     3601 atttaactca agcaaacgag ccaaacggtt gttacggttg ataacacggc ggtaaaggtc
     3661 attcaagtca gatgaggcaa aacggccacc atccaactgc aacattggac gaagatctgg
     3721 tgggataacc ggaaggatgt taagaatcat ccattcaggt ttgtttccag acttgtaaaa
     3781 ggcatccaaa acatccaaac gacggatggc tttgacacgt ttttgtccag tagctgtttt
     3841 caattcttct ttgagttcag caatttcttt ttcaagatct acttgcttca aaaggtcttg
     3901 gatggcttcc gcacccatct tggcaacaaa tgaaccataa ccatattcac gcaagcgctc
     3961 tcggtattcg cgctctgtca tgatagactt gtgctcaagt ggtgtatcct taggatcaat
     4021 caccacataa gccgcaaagt agataacttc ctcgagggca cgagggctca tatcaagggt
     4081 caagcccata cggcttggaa tccccttgaa gtaccagatg tgagatacag gagctttcaa
     4141 ctcgatatgt cccatacgct cacgacgaac tttcgtacgc gttacttcaa ccccacagcg
     4201 gtcacaaaca attcctctgt aacgaatgcg tttgtactta ccacaagcac attcccagtc
     4261 ttttgtagga ccaaagatca cttcatcaaa gagtccttca cgttctggtt tcaaggtacg
     4321 gtaattgatt gtttcaggtt ttttgacttc tccataagac catgaacgga ctttacttgg
     4381 agaagctagg gtgatttgca tacttttaaa acgatttaca tcaaccacta tttcttccct
     4441 ttctattcta agtgaactgc ttattcctgt tcagcagctt cttctgttgc ttccgctttt
     4501 gttgctttct cagcttcttc agcttcaaag gctgctttag cctcttgggc tgctttttcg
     4561 cgggcttttt caaggtcatc tacgtggatg acatcttcgt ccattccttc atccaagtcg
     4621 cgaagttcca cttcttggtc atcttcgtct agaacacgca tgtcaagacc aagagattgc
     4681 aattctttga caagaactcg gaaggattct ggaacacctg gttttggaat tggtttgcct
     4741 tttgtaatag cttcataggc tttcaaacgt ccgttgatat cgtccgactt gtaagtcaag
     4801 atttcttgaa ggacatttga cgcaccgtag gcttcaagag cccaaacctc catctcaccg
     4861 aaacgttgtc caccaaactg agctttacct ccgagtggtt gttgggtaac agttgagtaa
     4921 ggtccgactg aacgcgcgtg caatttatca tcaaccatgt ggtggagttt gatcatgtac
     4981 atgactccaa cagaaacacg gttatcaaat ggttcacctg tacgtccatc gtaaaggatt
     5041 gtcttggcat cgctatccat acctgcttct ttaacagttg accaaagatc ttcagaactt
     5101 gctccatcaa agactggtgt cgcaatgtga ataccaagag tacgagctgc cataccaagg
     5161 tgaagctcca taacctgacc gatattcata cgtgatggca ccccaagtgg gttcaacatg
     5221 atgtcgactg gagttccgtc tggaaggtaa ggcatgtctt ctacaggaac gatacgagag
     5281 acaacccctt tgtttccgtg acgtccggcc attttatctc cgaccttaat cttacgtttt
     5341 tgagcgatgt aaacacgaac caacatgtta acacctgatt gcaactcatc tccatttaca
     5401 cgtgtaaaga tcttaacatc acgaacgaca ccatcggcac cgtgtggtac acgaagagaa
     5461 gtatcacgca cttcacgaga cttgtctcca aagatagcgt gcaagagacg ttcttcagct
     5521 gaaagatctt tctcaccctt aggtgttact ttacctacaa gaatatcacc ttctttaacc
     5581 tcagcaccaa tacggataat ccccatttcg tcaaggtctt tgagggcatc ttcaccaacg
     5641 tttggaattt cgcgagtgat ttcttcaggc ccaagctttg tatcgcgcgt ttctgattcg
     5701 tattcttcaa ggtgaacaga tgtgtagaca tcgtccttca ccaagcgttc gctcatgata
     5761 acggcatcct cgaagttgta accttcccaa gtcatgtagg caacgattgg gttttgtcca
     5821 agcgccattt ctccattttc catagaaggt ccgtcagcga tgaaatcgcc tttttcaacg
     5881 acatcaccaa cttttacgag agtgcgttgg ttgtaagcag tacctgagtt tgaacgacgg
     5941 aatttttgga tgtggtaaac atccaatgaa ccatcttcac gacgaacttc taccttgtca
     6001 gcatctgcgt aagtaacttt accatcatac tgagcaatca cagccgcacc agaatcgtgg
     6061 gctgcttggt attccatacc agtaccaacg taaggtgcct gaggattaat caatggcaca
     6121 gcctgacgtt gcatattggc tcccatgagg gcacggttgg agtcatcgtt ttccaagaaa
     6181 ggaatacatg ctgtcgcaac ggcaactacc tgttttggtg aaacgtccat gtagtcaaca
     6241 atattagctg gatactcttg gttgacccct tggtgacgtc ccatgacaat cttctcagca
     6301 aaggttccat cttcattcag acgagagtta gcctgagcta cagtatattc atcttcttca
     6361 tcagctgtca accaaacaat ttcgttcgtg acaacacctg tttcacggtc aaccttacgg
     6421 tatggtgttt gaacaaaacc atatttgttc aagtgtccgt aagatgacaa gttattgatc
     6481 aaaccgatgt taggtccttc aggtgtctcg attggacaca tacgaccata gtgagtgtag
     6541 tgcacgtcac gcacttcata tccggcacgg tcacgagtca aaccaccagg tcctaaggct
     6601 gacaaacggc gtttgtgaga caactcagaa agcgggttgt gttggtccat gaactgtgac
     6661 aactgtgatg aaccaaagaa ttctttaact gcagctgtta caggacgaat attgataatt
     6721 tgttgtggtg tcaagacttc attgtcctga acagacatac gttcacggac attacgttcc
     6781 atacgagaaa gtcccaaacg tacttggttg gcaagcaatt caccaaccgc acggatacga
     6841 cgatttccaa ggtggtcgat atcatctaca cggccaagtc cttcagccaa gttgaggaag
     6901 tagctcatct cagcaaggat atctgcagga gtcaccgtac gaaccttgtc atctgggtta
     6961 gcattaccaa tgatcgttac gacgcgatct ggatcagttg gagcaataac cttgaatttt
     7021 tgaagaacaa caggctcagt cacaacggct gcatcgtttg ggatgtagac aatcttgttc
     7081 aagtcgccat ccaaatggct ttcaatgctt tcaatcacgc tacgagtcat aatcgtacca
     7141 gcttctacca agatttctcc agtttcaggg tctaccaatg gctctgcaat ggtttggttg
     7201 agcaaacgtg ttttaacatt gagtttttta ttgattttgt aacgaccaac tgctgccaag
     7261 tcataacgac gtgggtcaaa gaagcgagct acaagcaagc tacgtgagct ttcagccgtc
     7321 ttaggctcac ctggacgaag gcgttcgtaa atttctttca aggcttcgtc tgtacgagag
     7381 tccattggat tcttgtggat atctttttca acagtgttgc gaaccaattc gctgtctcca
     7441 aagatatcaa agatttcatc atcacctgag aaaccaagag cacgaaccaa ggttgtaaat
     7501 ggaatcttac gagtacggtc gatacgagtg taggtgatat cttttgagtc gctttcaagt
     7561 tccaaccaag ctccacggtt agggataaca gttgaaccat agcccacctt accatttttg
     7621 tctactttgt cgttaaagta aacacctggt gagcggacca actgagaaac gataatacgt
     7681 tcaccaccat tgatgatgaa agtacccatt tctgtcatga ttgggaaatc accaaagaaa
     7741 acttcttggg tcttgatttc gcctgtttct ttattgatca aacggaaggt tacaaaaatt
     7801 ggtgctgagt agctagcatc gtggatacga gcttcttcta gcgtgtattt tggttccttg
     7861 atttcatatc caacaaattc caactccatt gtgtctgtga agtttgaaat tggcaataca
     7921 tcttcaaaca cttccttaag accgtggtct aggaaagctt tgaatgagtc agtttgaatt
     7981 tcaatcaaat ttggtaagtc aagaacttct ttgattcttg aaaaactacg acgggtacga
     8041 tgtttcccgt attgaacgtc atgtcctgcc aagatgattc tcctttgtaa ataagttcca
     8101 agccttgtca atcaggcttt tctaatcgtc atatggttgt aaacccctta tcaccgtgtc
     8161 ctcttgacga attttcagaa tctttaagcc tctgttacaa atgctcataa tcttgaaaaa
     8221 aagcacaaaa agagcagcta aatctgactt tttcagaaga tttaactgct gtgagccttg
     8281 tctggacaat atttcagaca aaacctacga caaatgatta cccatattat accctattta
     8341 gctagatttt tcaaggggtt tcagtaggtt tttggtaaat tttttcccat agaaaacttg
     8401 gcatcacatt cgaatcacgc tatggtacaa aaaactgaaa aaactattga ctgaaaatca
     8461 ttttcaaggt ataataataa acgttaaggc ggtatagcca agtggtaagg cacggctctg
     8521 caaaagcttg atcgtcggtt caaatccgtc taccgccttc tataacttga tttatcaggt
     8581 ttcaaatgaa cagaaagccc aatttgaagg gcttttttta ttttccctcg aataaatacg
     8641 tataacttta aaaacttttg gagcgagttt gtggcagagt tctttccatg gcataattcc
     8701 cttttgaaat caattgaaaa aagcttcgtc acgcctggtg acaaaagcct ctagtttatt
     8761 ctgtttcttc ttctatttcg acttctgtga tttggacttt taccttggta acacgtccat
     8821 tcttcacttt atcattggtt aagataaact gtttgttttg gctgaccaat tcatagctga
     8881 gtttctcagt cgttggaatg gttcccactc ctgtcaaata ataaccagcg atggtatcaa
     8941 cgtcatcact ttccagctca acatcaaagt aattattgaa atcattgagg gtcatagttc
     9001 cttgaacaat gtaggtatcc tcgccaatct gatgaacatc tattgctgct ttgtccgttt
     9061 catcatcaat ttcaccaaca atttcctcta agaggtcttc caaagtcact aaaccagcca
     9121 taccaccgta ttcatccagc aagattgcca tttgtctttg ggtatttcgc agttctttta
     9181 gcaagtcatc cacaaaaata gtttcaggta caaaaagtgg atcttgtaaa attctcttcc
     9241 aaacaatatt gtcaaaaccg tccacaaagc ctgccttaag gagactcttg gtgtgaatga
     9301 ttccaattac attgtcctta tccccatcat aaaccgggat acgagaataa ttttgtttta
     9361 aaatactttg gataatggct tgactatcat cctgaatatc caccataaag gcatctgttc
     9421 gaggaaccat aacctctcgt gccatcagtt catcgagcga aaagacacct tgtagcatct
     9481 caatctcatc agcatccaat gtttcttcac tatttgtcag catataggca atttcatcac
     9541 gggtcatttt ttcatccgca tcatcgaatg acataggagt caaatggctc aagaaattgg
     9601 tcgaagcagc taaaagccaa acaaaaggac tgactagttt tccgatccca atgataaccg
     9661 gcgctgtacg aattgccaag gcatccttta gattaagagc gattctctta ggatataatt
     9721 ccccaaaaac gatggaaata taggtcaaaa atgccaagga tagaaaagtt gccacggctt
     9781 gtgctgtttc gccattccca agccaagagg caatcacacg tcctagagta tcagttaaac
     9841 tcgcccctga taagattgta atcagggtga ttcctacctg aatggttgat aaaaagtggt
     9901 taggattttc tagtaccttc agcaggcgga tgtagcgtct gtctccttct tccgcctttt
     9961 gttcaactcg ggcacgatta agagaaacca tggccatttc tgtggctgag aaaaaggcat
    10021 ttaataccgt caagataaac aataaaacaa attgtagcaa caaattctga ctacttgggt
    10081 cttccatagt tcttctccta aaatagtatc ttatccctta ttatatcaca aaatttaatc
    10141 caatacatat tatttttttc ttagcgtaac ttccatctct ctcccaaaac tggaagttag
    10201 gctaagacgg atttccactg atttcacgcg tttttctcat actaaaagct aggttgtggg
    10261 aaactggaag ttagttttag aagttactat tttttcttag tacctgttct aaccctgctt
    10321 aaactagtaa aaagaactcc tacatccata agtgacatag gagtttaggc ttatctttta
    10381 ctgagttaca gttacttctc cagttcggta atccagttga agtccctttt gaacattggg
    10441 aactagaaca ttgaattcca attctccatc cgaagacttg gcttcaatct gtgaagctga
    10501 gggaactaaa tcctcgtttg aagcgtagta aagggttaca cggtaacgga cacgcttgtt
    10561 ttggtccaag gctttacgca ccttgctttc atagtagttt tgaccagtcg aatactcggc
    10621 ttgtgcctga tttgcccagg ctgtctgaac agcaatgttt ttaggattgc ttgttgaggc
    10681 atcaaaacca tccaaaccac cgattaaggc atagcctaac aaatgacctc tatcgactgc
    10741 atgggtataa gagcccttta gattcttgac ctgatgccaa cctggaggag tccaagaagt
    10801 tgaaccattc ccagtttctt tacgattctt gtactgacga gtggccttag acaagagggc
    10861 attagctacg gttggaacag tttccttgcc cactgtcttt gttttattgt cagcgtaggg
    10921 cttacttgaa accttggcat ctagatttgt tttattacca ttgacgataa aagcacctga
    10981 gccattccac tccagactcc cctttatttg actcttgact gcgtctgtta agacactctc
    11041 tgccaatgct tgactaggag cttcagacgc ttgttttttc tgactaagct tggttttagg
    11101 actattagct gtcgactgca tctgcttgat ataatagctc cctgtagaca aaagcaataa
    11161 cactagcagt ccgattagtg tctgtcttgt ttttttgttc atatttctcc ttatctttag
    11221 aaaaaggctg gttctccagc ctaatttcct gtaaatttat gaatcaattc ctgccatttt
    11281 gctggagaca ggatagccca tggatcttga cccttgccca agattccata acctaccatt
    11341 aaaccgattc ctagagccag agtacctaaa atcagtacta tgatgactaa aagtaaacgc
    11401 ttgactacgt agcttgattt cttattcatc ttcatcactt gcctcaatcc gctgaatctt
    11461 agcacctagc tgcgccaact tctcatggaa accgtagtaa cctctatcca agtgaaccaa
    11521 tttaccgacc acagtttctc cctgtgctac caaacctgtc aaaatcaagg ccgcactggc
    11581 acgaaggtca gttgaaagaa cttctgctcc ctgcaaaggc tgtccaccaa caatacgagc
    11641 tgtatcacgg ataatctcag aatgcaagcc catgcggcgc atctcttcta ggtgttggaa
    11701 acgattttca aaaactgtct ccaccatggt tgattcgcct tttgcaactg tcatcaaggc
    11761 tgtaaattga gcctgcatat ctgttggaaa tcctgggtgg ggcaaggttt tcacatgaac
    11821 agcttttaga ttttccagtt gagaacgaac acgaattcct tcgtcttctt caattacttc
    11881 aacacccatt tcaagtaact tggcaatcaa gggacggttg tgctcccaga cagcgtctcg
    11941 aatcaagaca tcaccaccag tcatggcagc agctaccata aaggttcctg cttcgatacg
    12001 gtcctggact acattgtgag tcgtaccatg aagtttctca acaccagtaa tggttatagt
    12061 ctctgtacca gcacctttga ccttggctcc catttcatta aggagaatgg ctaagtcaac
    12121 aatctcaggc tcacgcgcag cattctcaat cactgtcacc ccatcagcca gagtcgctgc
    12181 catcatcaag ttctgcgttg caccaacact tggaaagtcc atatagatat gagcgccatg
    12241 caagcgttct gccttggctt cgatgtaacc agctgtctga ctaaccttaa cccccatagc
    12301 ttccagacct ttcaaatgaa gatcaatagg acggctacca atcgtacaac cacctggcat
    12361 ggataccttg gcatgaccca cacgggcaag gattggccct aatacaacga tggaggcgcg
    12421 catcttgctg acatacttgt aaggggcttc ctcagtgatg tcgccagtag catccacctt
    12481 gacaagatga gcttcctcat caaagtcaac cttggcattc aaaccaccaa ctacctgatt
    12541 cataataaag acatccgaca aaatcggaac attctgcaag acggtctttc cttcacttgc
    12601 tagaatagtc gctgccaaca agggtaagac tgcatttttt gctccctcga tcgtcacgct
    12661 tcctaccaga cgattatcgc caccttgaac cacaatttta tccatactcg tttcctttac
    12721 tcttgatttt ataataatcc tctaagcgct tcttgccaca aatgatacag gctaataaag
    12781 aaagaactca ggatgtagcc tatgacaatg ctaaaaaagg ctactaataa acgaactttt
    12841 cttgtattct cagctgtcac ttttaaaacc ttttcccatc taacaagatc ctttaaaagg
    12901 taaaaactca cataaataaa gagcatatga ctacttagag tgaataataa ttgaaccatt
    12961 tgactattat accatcttct ctgtttgtgc gctagtttgg aaacttcact caaaaattag
    13021 ggattgtttt tcaagtaatc aatcgcatct tgtagggttt taacgggcac gattttcata
    13081 tccgtcttga ttgttttagc cgcttctagg gctgtttggt agttgttttt cgcgtccgga
    13141 tgcgcctttt gttcttcttc gctaacaggg ttatcaggag caaagaaaat agcagcacct
    13201 gccctagccg aagctacaac cttcttatca atacctccaa tgtctcccac attaccatcg
    13261 cggtcaatgg tacctgtacc ggcaacaata cgaccattac gaagatctgg gtgagctatt
    13321 tgagtataga tagctagact aaacatgaga ccagcacttg gaccgccaat accagctgtt
    13381 gaaaagctaa ttgggacatt gctgattacc tctgtacggt caatcaagcc gattccaatt
    13441 ccatttttgc cattttccaa ggtgataatc tttccttctg cagacttggt ttgcccatcc
    13501 tcttcatagg tgaccttgac ggagtcccct aatttttgag aactgacgta atcaatcaag
    13561 tctttggaac tatcaaaggt ctgatcattg actgctgtga ctgtatcaga gatattgaga
    13621 atccctttaa aggttgaatt atccgtcaca ttcaaaacat aaactccaaa gtacttgagt
    13681 tcgatttcct taccagctgt ttttagtcct tgatacttgg ccatattttg cgatgtttgc
    13741 atgtagaatt gattgattcg cataaattca acatcggaag aaccacctgt agtctcctga
    13801 gcactacgaa tatctgtaaa aggtgtcaac caagcataaa tcatatgagc taaagtagca
    13861 tgttgaacac caaccgtaac gaattgatag gcaccagctt ccttatcttc tgtgtcattt
    13921 actttaagga cttggcgaat atcttccgaa ccacctggaa cctctatata gtagggcaaa
    13981 ggcaccacaa atgccaagaa ggtcacaatc aaggccgcaa tgacatacaa aggccatcta
    14041 atcttttttt tcatttctta tttcctccaa aatactctcg ggaacatggc aggcaatatc
    14101 ctgaccaaac ttcaaaagct ctcgaacacc tgatgaactg atatagagat gttcaggccg
    14161 gctatgtaaa taaatagtct ctatatcaga agacagctga tgattgtagt aatcaaaact
    14221 agcttcatat tgcaaatccg ccgcattcct caacccccgt actagaaaag tagcccccag
    14281 tctttttgca acatcgacca ccaatttatc atgagaagcc acgacttcaa cattttccaa
    14341 atgtcccaaa gccttttcta gcccccgttt acgattttca agagggagaa atccttgttt
    14401 gtggggatta aaaaaaatac ccacataaag cttatcaaaa agtctgctcg cccgttcaat
    14461 gatatccaga tgcccatttg tcatcggatc aaatgagcct gtgaataagc caatcttatc
    14521 tgacatagac tgtcacctta ctaattccat aaatcttttc cttccagata cccagacagg
    14581 caatttcttc tggaagttca acggctttat ccgtctcgca cacaaccata acatcttcag
    14641 aaaaaagctc tctctcagcc attttttcaa tatctgctac gatttgttcc ttggcatagg
    14701 gagggtctaa gaaaacgagg tcaaattccc cagatacctg ttccaatgcc ctttctgcat
    14761 ccatctttag gagttgaaat tttccaactt ccttggtcat ctggatattt tcagccacga
    14821 tggtctgagc cttacggtct cgctccacca aaacagcact ggacatgcca cgcgatactg
    14881 cttcgataga taaaccacca ctacctgcat aaaggtccaa gactcgtccc acttcaaagt
    14941 agggaccaat catgttaaaa atggctcccc taaccttatc cgaagtaggt cttgtcgtct
    15001 tgccttctag tgtcttgagg ggacgtcccc catagattcc tgatacgatt ttcatactgt
    15061 ttattatacc aaattataga caaaaagaga aagaaaaccg aaccttgcgg ttcgattctc
    15121 tacaaaatat tttcgtaagt atcgcggact tcttgaggcc aaacacttgt ttgcacttct
    15181 ccgatgtgtc tcttgcgaag taggaacatg gccatacgag attgtccaat tcctccaccg
    15241 attgtcaatg ggaatagacc attcaacaaa gacttgtgcc attccagttc caagcagtct
    15301 tcatcacctg taatttccac ctgacgtcta agagtttctt catctacacg aattcccata
    15361 gaagacaact caaaggctcc acctaaagac tcattccaga caagaatatc accatttaga
    15421 cccttgtagc cattctcaga ctcgcttgtc cagtcatcat agtctggtgc acgtccatcg
    15481 tgcggtttac catctggcaa ctcgccaccg ataccaatca aaaagacggc tccaaattct
    15541 ttacaaatcg cattttcacg ttctttcggt gtcaagtctg ggtagcgttc taccaattct
    15601 tctgtatgga taaaggtgat ttgttttggc aagatagact cgatgtcata gcgggcttca
    15661 acagctagct cagtcaggcg aatagcctta taaatcttct caactgtttc ttttagataa
    15721 acgatgttac gcttaccatt tgggataacc ttctcccagt cccactggtc aacataaaca
    15781 gagtgggttg catccaagga atcctcatct ggacgaaggg ctttcatgtg gacaaagaga
    15841 ccctctcctt caccaaagcc aaaacgagcc aaggtgtggc gtttccattt agcaagtgag
    15901 tgcaccactt cataagtagc atcagggatt tggagaacct tgaccgatac tggattttcc
    15961 acaccagaca ggttgtcctg cattccgtca ccgaccttac tcaagatagg accttgaact
    16021 tcgacaactt ctagcttatc tttcaaatac tgggtaaaag tgtttttgac aaaggaaatt
    16081 tcttcttgtt gatggataaa acttttcttc atagacaact cctcaaaaat ttaataaacg
    16141 tattatacac ctatttccaa gaaaagaaaa gagaaaattt aaaaaaaatc agtgtcactc
    16201 aaaacactga tttcatagac cttttagtca ttgcgaccaa agatacgtag aatacttagg
    16261 aaaagattga taaaatcaag atagatgctg agagccattg acaccaccca gcctgtcgct
    16321 acacgacctt gtgattgttc ataggcgagg cgaatctttt ggttatccca agcaatcaac
    16381 cctgaaaaaa ccaaaaccat ggctacgcta atcatataat caaagaagcc actagccaag
    16441 aaaatattga ctaccatagc aatcagtaaa ccaatgagag ctgccatcat tgctcgacca
    16501 atcccactca agtctttctt ggtaaagata ccaactgccg ccatgacaaa gaagagaagg
    16561 gcgctcgata caaaggcaga taaaactgta cccggagtat agaaagccac cacaaaacta
    16621 agggtaaagc cgtttaaaac ggagtaaagt aaaaatactg gaagagcagc tggactattt
    16681 cttgaagcca tgctactggc aacgaaaacc aaagccaact ccgcaaaagt agcaatggtc
    16741 aaccagagac gcccctgcat caaaaagtaa accaactgag actgaaaaac cgtcaacata
    16801 aggcctgata ccaaagcaga tagtccgatt cccagaccaa caaaggcata aaccttagcg
    16861 taaaattgat tgagacctgc acggtcatgt ataatagtgt gattcatcca tttctccttt
    16921 tctgtgaaca tctttccttg attataacaa aaaaagttaa aattagctta aatagaagat
    16981 taaaataccg gctgcaaccg caacattcaa actctcggcc tgccccttca tgctaatatg
    17041 gaccaactgg tctgcacttt cagccataag gggactaatt ccttgaccct catttcccat
    17101 aactagtaca aaattttcta tagaaggcag ttctctgtaa tcaacagaat ctttagatag
    17161 ggttgttgct agcactggga tagctacctt tttagtttcg tcaagaagcg cttgactagt
    17221 catccggtaa atgggcagat ggaaatgact accttgcatg gaacgtaggg ttttgagact
    17281 gtagatgtct gccgacttat ctgaaacaat cactcctgta aaacctgctg catccgcagt
    17341 tcgaatgata gttcctacat taccaggatc ttgcacatct tccaaaaaca agaacttgcc
    17401 ctgactcaaa tcagcttgtc ctacttcttc tttttgaacc acggcaacaa ttccctgtgg
    17461 agtctgagaa tccgccaaat ctagcaaaat atcctctgaa atccagacag tttgcggaaa
    17521 agcagctaac tgatttcgat aattttctag ggcaaagatt ttctcaatcg tcactccagc
    17581 ttggacagct tcttcaaaca agtgccagcc ttcaatcaaa taggcagact tgcggtattt
    17641 tttttggtgt aatttcttgg cattttttac cacagaattg gcttttgagg ttataatagt
    17701 catagaaata ttataacaca atcaaagggg tttggtatgc aaaaggttag aatgattgcc
    17761 caaggtaggg tacagggagt cggctttcgt tggggtgttt acagcttggc acttgaaatt
    17821 ggtggcatca caggtcgagt atggaataac gacgatggca cagtggaaat cttagcccaa
    17881 gcagactcat ctgctatcat ggcaaaattt atccaagaaa tccgaaaagg accgacacct
    17941 ttttcaaaag taagctactt agatgtcaaa ctaagcaact ttcctcccta ctatgacttt
    18001 aaaatcgcaa attaggtctc cagaactatt gtatattttg taaaaaaaca gtagaataga
    18061 aaggtataat ttttaaagaa ggaataaaaa cagtgaaatc tattaaacgt tttgcactct
    18121 cggctatggg agtggctatg ttgcttgtct tgactggctg tgtcaatgtc gataaaacca
    18181 caggtcagcc aacaggattt atttggaata cgatcggagc gcctatggct gaagctatca
    18241 agtacttcgc tactgataaa ggtctaggct ttggtgtcgc tatcatcatc gtaaccatta
    18301 tcgtgcgctt gattatcttg ccacttggta tctaccaatc atggaaggca acgcttcact
    18361 ctgaaaagat gaacgctctc aagcatgtcc ttgagccaca ccaaacacgt ctcaaagaag
    18421 caactactca agaagaaaaa ctcgaagccc aacaagccct ctttgccgct caaaaagagc
    18481 acggcatcag catgtttggc ggtgtaggat gtttccctat cctccttcaa atgcctttct
    18541 tctctgctat ctactttgct gcccaacata ctgaaggggt tgctcaagca agctacctag
    18601 gcattcctct aggttctcca agtatgattt tggttgcctg tgctggtgtc ctttactatc
    18661 ttcaatcgct cctttcactt cacggagtag aagatgaaat gcaaagagaa caaatcaaga
    18721 aaatgattta catgagccca ctcatgatcg tcgtcttctc cctcttctca ccagctagtg
    18781 tcacacttta ctgggttgtc ggtggtttca tgatgattct ccaacagttt atcgtcaact
    18841 atatcgttcg tccaaaactt cgcaaaaaag tccgtgaaga actagccaag aacccaccaa
    18901 aagcaagtgc tttctctaaa ccaagtggac gaaaagacgt tacccctgaa caaccaactg
    18961 ctatcacaag caagaaaaaa cacaaaaatc gcaacgctgg aaaacaacgt tcgagataag
    19021 aagaaaaagg cttagctagt ttgctaagtc ttttttgcaa gtc
//
LOCUS       DBEJZV010000039        18580 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.39, whole genome shotgun sequence.
ACCESSION   DBEJZV010000039 DBEJZV010000000
VERSION     DBEJZV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18580
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.39"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..393
                     /locus_tag="ACL3S0_001767"
     CDS             <1..393
                     /locus_tag="ACL3S0_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGR1312639.1"
                     /translation="DHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKP
                     ESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLK
                     NNLLFGTQDNNTIMAEAEKLLALLKENK"
     gene            812..1186
                     /gene="dhaM"
                     /locus_tag="ACL3S0_001768"
     CDS             812..1186
                     /gene="dhaM"
                     /locus_tag="ACL3S0_001768"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGR1312640.1"
                     /translation="MESIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGGIG
                     TSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNAAA
                     LLQAGAELSVIQTQLAELEINK"
     gene            1645..2358
                     /locus_tag="ACL3S0_001769"
     CDS             1645..2358
                     /locus_tag="ACL3S0_001769"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGR1312641.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2372..3019
                     /locus_tag="ACL3S0_001770"
     CDS             2372..3019
                     /locus_tag="ACL3S0_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312642.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCIGDFPHDFFDTYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3155..3808
                     /locus_tag="ACL3S0_001771"
     CDS             3155..3808
                     /locus_tag="ACL3S0_001771"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGR1312643.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3818..4282
                     /locus_tag="ACL3S0_001772"
     CDS             3818..4282
                     /locus_tag="ACL3S0_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGR1312644.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECATREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4295..5563
                     /locus_tag="ACL3S0_001773"
     CDS             4295..5563
                     /locus_tag="ACL3S0_001773"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGR1312645.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5577..5837
                     /locus_tag="ACL3S0_001774"
     CDS             5577..5837
                     /locus_tag="ACL3S0_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312646.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5848..7209
                     /gene="pdrM"
                     /locus_tag="ACL3S0_001775"
     CDS             5848..7209
                     /gene="pdrM"
                     /locus_tag="ACL3S0_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGR1312647.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSPLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            7363..8331
                     /locus_tag="ACL3S0_001776"
     CDS             7363..8331
                     /locus_tag="ACL3S0_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGR1312648.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8347..9339
                     /locus_tag="ACL3S0_001777"
     CDS             8347..9339
                     /locus_tag="ACL3S0_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex E1 component
                     subunit beta"
                     /protein_id="HGR1312649.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            9557..10600
                     /locus_tag="ACL3S0_001778"
     CDS             9557..10600
                     /locus_tag="ACL3S0_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGR1312650.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10646..12349
                     /gene="lpdA"
                     /locus_tag="ACL3S0_001779"
     CDS             10646..12349
                     /gene="lpdA"
                     /locus_tag="ACL3S0_001779"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGR1312651.1"
                     /translation="MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12413..13402
                     /locus_tag="ACL3S0_001780"
     CDS             12413..13402
                     /locus_tag="ACL3S0_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGR1312652.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13473..14543)
                     /gene="xerS"
                     /locus_tag="ACL3S0_001781"
     CDS             complement(13473..14543)
                     /gene="xerS"
                     /locus_tag="ACL3S0_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGR1312653.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSALENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(15118..16668)
                     /locus_tag="ACL3S0_001782"
     CDS             complement(15118..16668)
                     /locus_tag="ACL3S0_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGR1312654.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMSDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQILGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16684..17463)
                     /locus_tag="ACL3S0_001783"
     CDS             complement(16684..17463)
                     /locus_tag="ACL3S0_001783"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGR1312655.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17450..18301)
                     /gene="ylqF"
                     /locus_tag="ACL3S0_001784"
     CDS             complement(17450..18301)
                     /gene="ylqF"
                     /locus_tag="ACL3S0_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGR1312656.1"
                     /translation="MATIQWFTGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            18383..18575
                     /locus_tag="ACL3S0_001785"
                     /pseudo
     CDS             18383..18575
                     /locus_tag="ACL3S0_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844782.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         5649 a         3449 c         3937 g         5545 t
ORIGIN      
        1 gaccatgttc aaagaaacaa aaatggtcaa gctgatacca atcaaacgga aaaaccaagc
       61 gaggagaaac ctcagacaga aaaacctgag gaagaaaccc ctcgagaaga gaaaccgcaa
      121 agcgagaaac cagagtctcc aaaaccaaca gaggaaccag aagaagaatc accagaggaa
      181 tcagaagaac ctcaggtcga gactgaaaag gttgaagaaa aactgagaga ggctgaagat
      241 ttacttggaa aaatccagga tccaattatc aagtccaatg ccaaagagac tctcacagga
      301 ttaaaaaata atttactatt tggcacccag gacaacaata ctattatggc agaagctgaa
      361 aaactattgg ctttattaaa ggagaataag taaaggtagc agcattttct aactcctaaa
      421 aacaggatag gagaacggga aaacgaaaaa tgagagcaga atgtgagttc tagttctcat
      481 ttttttatga aaatgtgcaa aatatagtag attgaaatta gaatagtata cctctacttc
      541 taaaacattg ttagaaatcg atttgactgt cctgttctta tttcatttta ctatatctta
      601 acagatagtg taaataaagg taaactattt actggctaat taatcagtta aacactagtt
      661 aaggagtaat gataaaaaag aacaatacta ttattgatgg ccagtctgtt ggctcttgtc
      721 ttaggagcat gtggtttttt ggacatatcg atcctggatc attctcatca ggattactat
      781 ttactgctat tttagaaact ggggtggttt gatggaaagt attggtcttg ttatcgtttc
      841 acattccaaa cacattgcag aaggtgttgt tgaactgatt agtaaagtag ctaaagatgt
      901 tccgattact tatgtaggag gaaccgaggg cggaggaatt ggaacgagtt ttgatcaagt
      961 agatagggtt gtttccgaaa atccagcaga tactttactt gccttttttg acctaggttc
     1021 tgctaaaatg aacttaaaaa tggtgactga tttcagtgat aaaagtatca tcatcaacag
     1081 ggttccaatt gtagaaggtg cctataatgc agctgctctt cttcaggctg gtgcagaact
     1141 gtcagttatt caaacacagt tagcggagct tgaaatcaat aaataaggaa ttttactata
     1201 actcttttta taggtaagct attgattatc tcaactataa aatgttaagt aaatgatttc
     1261 aaaatcagaa agggattgct ttatgcagtt cctttttatt ttaacaggag tgaaactata
     1321 gtgtttctaa attgtgaatc aatcaaaact gattgtgatg gggctattct agctttagaa
     1381 tccttcaaaa attaaaattt aaggcaatca attacttgga agagtatgaa agcatttagt
     1441 ttataggaat tctaggccta gaattacata tgtatttatg aagacggggt gttcgatagt
     1501 tagtattgtt ctattctgaa agatttgagc tgtcagttgt atagaaagtg ttcgaatttt
     1561 ttttaagtga ttaaattagt taattgtatg aggtgcttta tgatataatg ttcttaatga
     1621 attttcagaa aggaaaacct caaattgttc tacaaatttc tactcttcga cctcgaccac
     1681 actcttcttg attttgatgc tgctgaggat gtggctttga cccaacttct aaaagaagaa
     1741 ggagttgcgg atattcaggc ttataaagat tattacgttc ctatgaacaa ggctctctgg
     1801 aaagacttgg agctgaagaa aatcagtaaa caagagctgg ttaacacgcg cttttctcgt
     1861 ttattttctc attttggaca ggaaaaagac ggtagttttc ttgcccagcg ttaccaattt
     1921 tatctcgctc agcagggaca aacactatcg ggcgctcatg atctcttgga cagcctcatt
     1981 gagcgtgatt atgacttgta tgctgcgaca aatggcatta ctgccattca gacaggacgt
     2041 ttggctcaat ctggtctagt accttatttc aatcaagtct ttatctcaga acagttgcaa
     2101 actcaaaagc cggatgctct cttttatgaa aagattggcc agcaaattgc tggatttagt
     2161 aaagaaaaga cgctgatgat tggagattct ctaaccgccg acattcaagg tggcaataat
     2221 gcggggattg acactatctg gtataatcct catcacctcg aaaatcacac acaagcccag
     2281 ccgacttacg aagtctattc ttaccaagac ttgctggatt gtttagataa aaatattctt
     2341 gaaaagatca cattttaaag gagattagct aatgactaca aaaaaagcta atattactat
     2401 tgaagagtac attgaaatgt ctgaagttga ttttaatgaa gctgttaatt atgaatttac
     2461 atctgacact tgtcaattag caaatagtat ttatcaatct ctttttaagt tttttgataa
     2521 gaaaaatttc tctggcgatt taatttttac ttggaaatct ccatcattag tcaaagaagg
     2581 ggattatatt gggagaaggg attcacaagt agataatctt agagtaatag gaaatatatt
     2641 tccgaattat cttactaatc gaaaatatag cctcaatatg aatcgtaatg gctgtatagg
     2701 agattttcct catgactttt ttgatacata cctagatcat gtagcaaaat atgcctacga
     2761 acaaaaagtt aataatatta aagagtatta tcctttaaaa agagcgattt tacaccaaga
     2821 gaatgcattg tattttcgat tgttttctaa ttttgatgac tttttagaaa aaaattattt
     2881 aaagactata tggcaagttt ctaaagaaac tcctttttct gaaatggatt ttaatatgtt
     2941 taaaaatatt tcagaaaaga taatcttcga aagaggtagt aaaatgctta atgatttaaa
     3001 aagtaattat aaaaaatagc cagtctttat aaactgtatt cacgtattca aatcgtatat
     3061 agtcgattta ttaaatcttt agataaattg taaaaagtgg tttccatagc cactttttgc
     3121 tataatagag gcagtaaaaa tgaaggagtc agctatggaa cactcgtctt ggcatgcttt
     3181 gattaaggcg caattacctg agggttattt cgggaaaatc aatcagttta tggagcaggt
     3241 ctattctcag gggattattt atccacccaa ggaaaaggtt tttcaggctc tcttgacaac
     3301 actgcttgaa gaagttaagg tggtaattct agggcaagac ccctatcacg gaccaggtca
     3361 agcgcagggc ttgagttttt ctgtacctga ctctatccca gctccaccat ccttgcaaaa
     3421 tatcttgaaa gaattgtcag atgatatcgg agttaagaaa tctcatgatt tgacagcttg
     3481 ggctgagcaa ggagtcttgc ttcttaatgc ttgtttgact gttcctgctg gacaggccaa
     3541 tggtcatgct ggtcaaatct gggagccttt tactgatgct gtgattcagg tggtcaatca
     3601 tctagataga ccagtcgttt ttgtactctg gggagcttat gcacgtaaga agaaggcctt
     3661 agttaccaat cctcatcact tgattatcga atcagcccat ccaagtcctt tgtcggttta
     3721 tagaggattt tggggttcca agcccttttc caaggccaat gcattcttaa aagagacagg
     3781 acaagagcca atcgattggc ttagataagg agaaaatatg cctcagttag cgacgatttg
     3841 ctacattgat aatgggaaag aactgctcat gctccatcgt aataagaaac ccaatgatgt
     3901 ccatgaaggg aaatggattg gtgtgggtgg taagctagag agaggagaga cgccccagga
     3961 atgcgcgacg cgtgaaatcc ttgaagaaac agggctcaaa gccaagccag ttctaaaagg
     4021 tgtcatcact tttcctgaat ttacaccaga tttagactgg tacacctatg tttttaaggt
     4081 gacggagttt gagggcgact tgattgactg caatgagggg acgctagaat gggttcccta
     4141 tgatgaggtt ttgagcaagc cgacttggga aggtgaccac acctttgttg agtggctttt
     4201 agaggataaa cccttctttt cagccaagtt tgtttatgat ggggataaat tgttggatac
     4261 ccaagttgat ttctatgaat aaaggagaaa gcagatgcta ctaatcaaaa atggtcgtgt
     4321 aatggatccc aagtctggtt tggatcaagt ttgtgatgtc ttagttcaag atgggaaaat
     4381 tatcaaaatt gcgcctgaga tcacggaaga aggagcagaa acgattgatg ctactggtct
     4441 tgtggttgct cctggtttgg tcgatattca tgtgcatttc cgtgaacctg gtcaaacaca
     4501 taaagaagac attcatactg gtgccctagc agccgctgca ggtggtttta ctactgtcgt
     4561 catgatggct aataccagtc caaccatttc agacgtggag actttgcaag cagttctcca
     4621 gtcagctgcc aaagagaaga ttaatgtcaa gacagttgcg accattacta aaaactttaa
     4681 tggtaaaaac ttgactgact ttaaggcact cttagaagct ggtgcggttg gtttctctga
     4741 tgacggtatt ccgcttgaga gcagtaagat tgtcaaggaa gccatggagg aagccaaaaa
     4801 actcaatacc tttatcagcc ttcatgagga agatccaggt ttgaacggtg ttcttggctt
     4861 taatgaaaat attgctagag aacatttcca tatctgcggt gctactgggg tggctgagta
     4921 cgctatgatg gcgcgtgatg tcatgattgc ctatgcaact aaagcccatg ttcacatcca
     4981 gcatttgtct aaggaagaaa gtgttaaagt agtggagttt gctcaggggt taggtgcaga
     5041 agtcacagca gaagtagcgc cacagcattt ctctaagaca gaagcacttc ttttaacaca
     5101 aggtagcaat gctaagatga atccaccgct tcgtttggaa tcagaccgtc gtgccgttat
     5161 cgaaggtctc aaatcaggtg tcatcacagt tattgcgact gaccacgcgc ctcatcatgt
     5221 agatgaaaaa aatgttgagg atattaccaa agcgccatct ggtatgactg gcttagaaac
     5281 atccctgtct ctcagcttga cctatttagt agaagctggt gagttgagct tgatggaatt
     5341 acttgaaaaa atgacataca acccagccaa gctttacaac tttgaagcag gttacttggc
     5401 tgagaatggt ccagcagata tcactatttt tgatgccaag gctgaccgct ttgtggactc
     5461 ccattttgct tccaaagcag ctaattcacc attcatcggt gaaaccttaa aagggcaggt
     5521 taaatatacc atctgtaagg gacaaatcgt ctatcaagct tgataggagt tagaatatga
     5581 attattttcg aaaacgtagg gagagacaag cgaaatctaa tagtggaatt tactgtcccg
     5641 cagctaatcg ttccaaaatt caatatgaaa ctaaagaaaa agctgaccat gcggttcaat
     5701 atgataacgg aggtttagtt agaagctatt attgtcgtac atgtgcgtgt tggcatacta
     5761 cttcaaaatc taataaacct ccgctaagtt tgaaaaacta tggtctgaaa ctctttggtt
     5821 tagataaatc agaatagaaa gagaagtatg tataagacaa agtgtttacg agagaagtta
     5881 gtattatttt taaaaatttt cttcccaatc ctgatctacc aatttgccaa ttattctgcc
     5941 tcttttgttg atactgcaat gacaggtcaa tacaacacta tggacttggc tggtgtatct
     6001 atggcaacca gtatctggaa tcctttcttt acatttctaa cagggattgt gtcagccttg
     6061 gtgcctatca ttggtcacca tcttggtcga ggcaaaaagg aagaagttgc gtctgatttt
     6121 taccaattta tttatttggc cttgggccta tctgtggtct tgctggggat ggtacttttc
     6181 ttggcaccaa taatcttgaa tcatattggg ttagaagcag cagtagcggc agtagcggtt
     6241 cgctatcttt ggtttttatc tatcgggatt atccccttgt tgctctttag cgtcattcgt
     6301 tccttgctgg attcgctggg cttgaccaaa ctgtccatgt acctcatgct tttgttactc
     6361 cctctcaata gcggatttaa ctatctcttg atttacggtg cctttggtgt tccagaactg
     6421 ggaggggctg gtgctggttt aggaacatcc ttggcctact gggtcttgct tgggatttct
     6481 gttctggttt tatttaaaca ggagaagctc aaagccttac accttgagaa acgaattcca
     6541 cttaatatgg ataaaattaa ggaaggagtt cgtttaggtc tgcctattgg gggaactgtc
     6601 ttcgcggaag tggctatctt ttcagtggtt ggcttgatta tggctaagtt ttcgcccttg
     6661 attatagcta gtcaccagtc agctatgaac ttttcaagtc ttatgtacgc ctttcctatg
     6721 agtatctcat cggctatggc tattgtcgtt tcctatgaag tgggagccaa gcgatttgat
     6781 gatgcgaaaa cctatattgg tctaggaaga tggactgccc tcatttttgc ggccttcacc
     6841 ttaaccttcc tttacatttt taggggaaat gtggccagtc tttatggtaa cgacccaaaa
     6901 tttatcgatt tgacagtgcg ttttttaact tatagtcttt tcttccagtt agcagatacc
     6961 tttgcggcgc cgcttcaggg aattttgcgg gggtataagg atacagttat tcctttttac
     7021 cttggtttgc ttggttattg gggcgtagca atccctgtgg ctacgctatt tgattcccta
     7081 acagattttg gagcttattc ttactggatc ggcttgatta ttagtttgat tgtgagcggg
     7141 gcgctctacc gttggcgttt aactgtgatt atgaagagat ttgaatcttt agcaaaatcc
     7201 aaatgctaaa aagtttgtga aaaaatattc ttgacaagaa aatcccttgt tttcacgggg
     7261 ttttcttttt tattttgtga aatttctttt agaaaaactt tgacagtatt tgccaaaagc
     7321 ggtaaaatag taaggtaaga agaaagttag aaaggcaaga agatgtcaac tttagataaa
     7381 aatcttttgc tagaaatgtt ccgtaagatg gaagaaatcc gtcgcatgga cttaaaaatt
     7441 gcacaattag taaagaaagg gaaagtgcca ggaatgacgc acttttctgt tggtgaagag
     7501 gcagctaacg tgggggctat gttagctctc aatccagatg atctgattac ctcaaaccac
     7561 cgtggacacg ggcaagctat tgctaaaggg attgacctca acggaatgat ggctgaaatc
     7621 cttggtaaat acactggaac ctgtaaaggg aaaggtggat ctatgcatat cgctgacctt
     7681 gatgctggga accttggtgc caatggtatc gtaggtggtg gtatggggat cgctgtcggt
     7741 gcagccctca gtcagcaaat gcaaaatacc ggtaaaatcg ttgtctgctt ctttggagat
     7801 ggtgcgacca atgaaggtgt tttccacgaa gcagtgaaca tggcttctat ctggaacctg
     7861 ccagtcattt tctattgcat taacaacggt tacggtatct ctgcggatat caagaaaatg
     7921 accaatatag aacatatcca tcaacgtagc gccgcttatg gaattcctgg aatgttcatc
     7981 gaagacggta acaatgtcat cgatgtctat gaaggatttc agaaagctgt ggaccatgtt
     8041 cgcagtggca atggtccagt cttgattgaa agtgtaactt atcgctggct cggtcactca
     8101 tcatctgacc ctggtaaata tcgtacgcgt gaagaagtgg aattgtggaa acaaaaagat
     8161 ccaatcgaaa acctccgcaa ttaccttatt gaaaataaca ttgcaagtgc cgaagaattg
     8221 gaagaaatcc aagcgcaagt aaaggaagca gtagaagctt ctgttaaatt tgcagaggaa
     8281 agcccattcc caccgcttga atcagccttt gaagatattt acgcagacta aggagaaaga
     8341 gataaaatgg aaacaaaaac aatgtccttc cgtgacacca ttatccttgc tatgtctgag
     8401 gaaatgcgtc gcgatgaaaa tgtgttcttg atgggagaag acgtcggtgt cttcggagga
     8461 gacttcggta cttctgttgg aatgcttgaa gaatttggtc cagaacgtgt ccgtgactgt
     8521 ccgatttctg aagctgccat ctctggagca gcagcaggag cagccatgac aggacttcgt
     8581 ccaatcgtcg atatgacctt catggacttc tctgttattg ccatggacaa tatcgtcaac
     8641 caagctgcta aaacacgtta catgtttggt ggtaaaggtc aggttccaat gactgttcgt
     8701 tgtgcagctg gtaacggagt tggctctgcc gcccagcact cacaatctct agagtcttgg
     8761 tttactcaca ttccaggact taaggttgtg gcacctggaa cacctgcgga catgaaaggc
     8821 ctgcttaagt cttctatccg tgataacaac ccagttatta tacttgagta caagtcagaa
     8881 tttaaccaaa aaggggaagt gccagttgat ccagactaca caattccact tggggttggt
     8941 gaaatcaaac gccaagggac ggatgtaaca gttgttactt atggaaaaat gcttcgccgt
     9001 gtggttcaag ctgctgaaga attagcagaa gaaggaattt cagttgaaat tgttgaccca
     9061 cgtacccttg ttccgcttga taaggatatc atcataaact cagtgaagaa gactggtaag
     9121 gttgttctgg tcaacgatgc ccacaaaaca agtggctata tcggtgaaat ttcagctatt
     9181 atttcagaat cagaagcatt tgactatcta gatgcaccaa tccgccgttg tgcaggagaa
     9241 gatgtgccga tgccttatgc acaaaaccta gaaaatgcaa tgattccaac agttgaaagt
     9301 atcaaagatg caatccgaaa aacttataac aaagactaga gttacataag ataagttatg
     9361 taaataaaac aaagctgacg agaaactttg tatcttttag gtgcagagct cttcgtcatt
     9421 aatatcttag attagagcac gggctaaaag ctcggaaaaa agataaatct ccttggcttc
     9481 atcgaagcca tcgtcgattt cctatttttc agtcgctttt gacgcccttt gtatcataaa
     9541 tagaattgga gaggtcatgg ctgatgacaa gctaagagcg actcctgcag ctagaaagtt
     9601 agcggatgat ttagggataa acctctacga cgtttctggc tcaggtgcaa acggtcgtgt
     9661 ccacaaagaa gacgtggaaa cttataaaga cacaaacgtg gttcgcattt cgccacttgc
     9721 aaaacgaatt gccctcgaac ataacattgc ttggcaggaa atccaaggaa ccggtcatcg
     9781 tggtaaaatc atgaagaagg atgttttggc cctgcttcct gaaaatatcg aaaacgatag
     9841 catcaaatct cctgctcaga ttgaaaaagt ggaagaagtc cctgataacg taacaccata
     9901 tggtgaaatc gagcgtattc caatgacacc aatgcgtaag gttattgccc aacgcatggt
     9961 tgaatcttac ttgactgcgc caaccttcac cctaaactat gaagttgata tgactgaaat
    10021 gttggctctt cgtaagaagg ttcttgagcc aatcatggaa gcaactggga agaagactac
    10081 tgtaacagac cttctttcac ttgcagttgt taagactctt atgaaacacc catacatcaa
    10141 cgcttcattg acagaagatg gcaagactat tatcactcac aactatgtca atcttgccat
    10201 ggcagttggg atggataatg gattgatgac acctgttgtt tacaatgctg agaagatgag
    10261 tctttcagaa ctggttgtag cctttaagga tgttattggt cgtaccttgg atggtaaatt
    10321 ggctccaagt gagttacaaa attcaacatt cacaatcagt aatttgggaa tgtttggtgt
    10381 tcagtccttt ggtccgatta ttaaccaacc caactcagct atccttggtg tcagttcgac
    10441 aatcgagaag ccagttgtcg tcaatggtga aattgtgatt cgcccaatca tgagtttagg
    10501 attaaccatt gaccaccgtg tcgtagatgg tatggctggt gctaagttta tgaaggactt
    10561 gaaagagttg attgaaacgc caatctcaat gttaatttaa gagcaagagt attcattttt
    10621 aagatataga taaaggaagg aagacatggc cttagaagta attatgccaa aagccggcgt
    10681 ggatatgaca gaaggacaaa tcgtccaatg gaataaaaaa gtcggagaat ttgtaaaaga
    10741 aggagaaatc cttttggaaa tcatgactga taaagtcagc atggaattgg aagccgaaga
    10801 agatgggtac ttgattgcca ttctcaaagg agatggtgaa actgtccctg taacggaagt
    10861 tatcggttac cttggtgaag aaagggaaaa catcccaaca gctggagcag catcgccaga
    10921 agctagccct gtacctgtag caagtacctc aaacgatgat ggtaagagcg atgatgcttt
    10981 tgatatcgtt gtgattggtg gaggtcctgc tggttatgtt gcagccatta aagctgccca
    11041 actcggcggt aaggttgccc ttgttgagaa atctgaactt ggtggaacct gcttaaaccg
    11101 tggatgtatt ccaaccaaga cctaccttca taacgctgaa attattgaaa atatcggtca
    11161 tgctgcaaat cgtggtatcg tgattgaaaa tcctaacttc actgttgata tggaaaaact
    11221 tttagaaact aaatctaaag ttgttaatac tcttgttggt ggtgttgcag gacttcttcg
    11281 tagctacgga gttactgttc ataaaggaat tggtacaatc actaaagaca agaacgtctt
    11341 ggtaaatggt tctgaattgc ttgaaaccaa gaaaatcatt cttgctggtg gttcaaaagt
    11401 cagcaagatc aacgtccctg gtatggaatc tccacttgtc atgactagtg atgacattct
    11461 tgaaatgaac gaagtgccag aaagccttgt tatcatcggt ggtggagttg tcggtatcga
    11521 actcggtcag gccttcatga cgtttggttc aaaagtgact gttatcgaaa tgatggaccg
    11581 tatagttcca gctatggatg cggaagtttc taagaacctt cgcttgatcc ttgagcgtaa
    11641 aggaatgacc atcttgactg gtactaaact gcaagaaatc attgaggaaa atggtcaact
    11701 tcgtatcaag gttgaaggaa aagacgatat catagcaagc aaagctcttc tttcaattgg
    11761 tcgtatgcca gaccttgaag gtattggaga ggttgagttt gaattggatc gtggttgtat
    11821 caaggtcaat gaatacatgg aaacttcagt tccaggcatt tatgcaccag gtgacatcaa
    11881 cggtactaag atgttggctc acgcagcttt ccgcatgggt gaagtttccg ctgaaaatgc
    11941 ccttaaagga aatcatgcag ttgccaaatt gaatttgact cctgcagcca tctacactct
    12001 ccctgaagta gcagcagtag gtttgacaga agaacaagcc cgtgagaaat acgatgttgc
    12061 catcggtaag tttaactttg ctgctaatgg tcgtgctatt gcatctgacg cagctcaagg
    12121 tttcgtaaaa gttatcgctg ataagaaata cggagaaatc cttggtgtac acattattgg
    12181 tcctgcagcc gcagaattaa taaacgaagc atcaagcatc atcgaaatgg aaatcactgt
    12241 tgaggaaatg ctgaagacca tccacgggca cccaacttac tctgaagtga tgtacgaagc
    12301 gtttgcagat gttctaggaa tggccatcca ttcacctaag aaaaaataaa acgaagatag
    12361 attagactgg aaggttattt ccagtttcta tcatataaag taaagggata tcatgaaata
    12421 cattatcaat cattcaaatg acactgcttt taatattgcc ttggaagaat acgcctttaa
    12481 acaccttttg gatgaggatc aaatcttcct actttggatt aacaagccat ctatcattgt
    12541 tggtcgtcac cagaacacta tcgaagaaat caaccgtgat tatgttcgcg aaaatggtat
    12601 tgaggtagtt cgccgtatta gtggtggtgg agctgtttac cacgatttaa ataacctcaa
    12661 ctacacgatc atctccaaag aagatgaaaa taaggcattt gacttcaaga gcttctcaac
    12721 tccggttatc aataccctgg ctcaacttgg ggttaaagct gagttcacag gtcgtaatga
    12781 ccttgagatt gatggtaaga agttctgtgg taatgcccaa gcctatatca acggccgtat
    12841 catgcaccac ggttgcttgc tctttgacgt tgatttgtca gtcctcgcaa atgcccttaa
    12901 ggtttcaaaa gataaatttg aatcaaaagg tgtgaaatcc gtccgtgccc gtgtaaccaa
    12961 tattatcaat gaattaccaa aaaaaatcac agtcgaaaaa ttccgtgatt tactcttgga
    13021 atacatgaaa aaagagtacc cagagatgac tgaatacgtc ttttcagaag aagaattggc
    13081 cgaaatcaat cacatcaagg atactaagtt tggaacttgg gactggaact atggtaaatc
    13141 acctgaattt aacgtccgtc gtggaaccaa attcactagt ggtaaggttg aagtctttgc
    13201 taacgttact gaatcaaaaa tccaagacat caagatttat ggtgacttct ttggtattga
    13261 agacgttgct gcagtagaag atgtccttcg tggggtgaaa tacgaacgcg aagatgttct
    13321 taaggcgcta aaaaccattg atatcacacg ctacttcgct ggtattagcc gtgaagaaat
    13381 cgctgaagcg gtagttggat aaatcaaaaa gaagttggcc aactaaccaa cttctttttg
    13441 atatttattt acataattta aaatacgtaa aattataaac tatctagagc attcttttgt
    13501 tcatcattaa caatatgggt atagaggtca gtgacttgtg tgctggcatg tcctagttgg
    13561 tgactgacta aaacttgtga tttagtcgca tcatagagcc tagttgctag cgtatggcgc
    13621 agtttatggg gtgttacacg cactttaaaa tcctctgagt atttagcaac cattttctca
    13681 acgctagaag catcgatacg attaggaaca cctctgtaga gagttaaaaa aagggctgta
    13741 tctgtttttt ccgttttata gcgttgattc cgaatggcca gataattctc taaataaggt
    13801 ttagcaaaag cagcgacatt gactgagtca cgtttgccac cttttcgagt aacatcaata
    13861 accatcattt ttagattgag atctcttaga tctagattaa cagcttcaga taagcgaaca
    13921 ccagatgcca agagaagggc aataatggct aaatctcgtt ctttattttt gttgaatgat
    13981 gagagagctc gatttgaaag ctgttgtggg tgctcttgat cgatataagt tagaaaacct
    14041 tctgtttcat cacctagaaa gagtttttgc ttgatatttt cagctctggc agcaagggtt
    14101 tctttctttt tcttggttga aacttttttc attacattac gatagaaata aggttccccc
    14161 tgatcgtttt caacctcctc ggttagatac ttgtaaagac tagaaagtgc tgataaggtt
    14221 cgattgatag ttgtctgtga aacaccttgt tttgttgtat tagcattcag caagggacgt
    14281 tcacgtagat aaaggataaa ggattccatg tctttcttag acatattttc caaagctgat
    14341 aaaggaatat cggatatttt atcagcgttt gaaataccag actccaaaac ccagctgaaa
    14401 aatcggtcat attccttaag gtattcgtac agggttgtaa aactgtaggg tacagccagc
    14461 ttagattggt agtattccag aacataccag ggcatgagtt gttttagttt gtcgattcgt
    14521 tccagtaaaa tctcacgttt catgtatttt ctccataagt aagtatacta gtagtatagc
    14581 atagacttgt atatttttca agaaaattat agtttttcag aaagatgtta taggagtttt
    14641 tcaaagtgat aaaaagactt agacctacaa acaaaacaga ataaggaaaa tctcacccac
    14701 taaacttctg ttaatactac ataactgaag agctatataa ggagctatga gatacaaaac
    14761 acattgtata atagattgaa actagaatag tacatctgga cttctaaaac attgctagaa
    14821 attgatttga ttgtcctgat tgttttatcc tatttctatt tcatttcact atataattgc
    14881 tattgttttc tttttcatga ttttaatctt actgtacaga tttgatacag taaactcctt
    14941 tccagcttta tgctttatca tttctaactt aattatagtc ttatttttaa taaagttcaa
    15001 ttatttatat gtaaaattcc tcatcagtaa aaaataaccg atctcatttc tgagaatcgg
    15061 ttttctaaat aaatcaaact gatcatttac ataacataaa ttatgtgaat gatcatacta
    15121 caacaacaaa tctttgactt ttccaatttc actttttgga ataaccaggt gaatcatatc
    15181 acccagatac attctggttg agccgttaac tgtttggctc ttgccattat ggacttgagt
    15241 tgtgatgagg acgttgtgtg gtaagttgag ttcatgaact tgtttcccag caattttatc
    15301 agaaactggt atttcgataa gtgtaacttc tccttcgcta gatacttctt ctggaagcat
    15361 tttttccagc atggcttcat agactggcgt acctttgagc aaatccatga taatataaga
    15421 aacaagagtg acaagaccaa gtggcatgag gttgcgaata tctcctacca tctcagttac
    15481 gaggatcata gcggttaagg gagcttttga tatggctcca aaatagccac tcattcctag
    15541 aatgacaaat atagggaatt gctcttgact gacaagtcca agattgacac agataacacc
    15601 aactaaggca ccaagcaaag aaccaagagc taaaatgggt aggaaaattc ctcctggcag
    15661 tccacttcca tagctaatca tactccaaat aaagcggatc aaaaagtaag ctaataaaac
    15721 ttggaaacta aaattttgtt cagttaaaga aaggacaagc tgatttccgc caccaaggat
    15781 ttgaggtaag aagattccga ctggtatgat aaggataaaa gccaagatgg gataataagc
    15841 cctatccaaa tggatttttt gaccaatcaa gtcataaact cttccaacgt ttaatacagc
    15901 tttctcatag agaaaacctg aaaatccaag gaaaattccc atgacgagat atatccaata
    15961 ctggtctagg gtcatgggag gaatgttatc tgacatatcc aatactggtg tcaaaccgaa
    16021 catgagtaga gacacaaagt ttgctacgat gctggctgct agagttgaga cccagaaaaa
    16081 gcgcgaaaaa tggtgataga cttcttctac aacaaagaga agtgctgcaa taggagcatt
    16141 aaaggctgcg gctaaacctg ctgcagctcc actggcaatc aaggaacgtt cctctactgg
    16201 actggatttg agccacttgg caattccttt accaccaact gctccaagtt gaatgctggg
    16261 tccctctcga cccagcatga gtccactggc aatagcaaga atacctagca catatttttt
    16321 ccaaagaatg ccccaccagt tgagggacat gaggcctttc agttcggctt cgacttgagg
    16381 aattcctgag cctttaatat ctttttctga ccgtgttagt ttggcactga gccaacagat
    16441 gagtatataa aacaaaacca gtacaaaaag attgcgcact aagtaccctt gatcttgata
    16501 aactccttgt atcaggtgga agcccttttc aattaagaaa cgaaaggatc cgacgataat
    16561 tccaacgatg aggccgacaa tgattcctcg accaacttgg gatagtatag tgctggatgc
    16621 aaaggcgaat tctttcttag aacggactat ttccgactgt tcctccatgg tatttccttt
    16681 caattaactt tcttttttac ctaaaaccag tgatttaacg ggttcaaagc tggttcggtg
    16741 aattggggta actcctagtt ttgtgaggcc ttccagatgt ttagctgtgc catatcctgc
    16801 attagtagcg aaatcatagc cagagaactg ctgatcgtat tctttcatca attcatcacg
    16861 tgttaccttg gctactatag atgctgctgc gatagagagg gagttggcat ctcctttgat
    16921 aatggaggtt tgtgaaatgg gcaagtccag tttcatggca tcaatcaaaa ggtgctctgg
    16981 ttgagggctg agctgggaga ttgcttcttg catggctagt ttggttgctt catagatgtt
    17041 gacttggtcg atgacctgat tatctatgat accaattcca atcgacaagg cttggtcttg
    17101 aacggcttgg aaaatctcca gatgtttctt tttaggaatt ttcttgctgt cgttgagacc
    17161 tttaatctta caatttttag gtaaaataac ggccgcagcg actacaggac cagcaagagg
    17221 accacgacca acctcatcaa tacctgcaat taaggtcaat ccttgcttat aaagttcttt
    17281 ttcataagaa agcatggatt ccaagcgcaa attttcatct aattcagctt gaatggctct
    17341 tttacgcttg ctgatttcct tttgaactcc tgagcgatta tccttttcaa gatctaaaaa
    17401 aatagggctt tctaactcct tgactgtcac aaggagttct ttgatttctt taatcgttgc
    17461 catcgaggtc ttccaatgta tctaaggtat agttaccgag tttgccatca cggacttcct
    17521 tcacgaagag actgtaaaaa cggtcatagt catcacggaa accgagggcg cgggtcatat
    17581 ccataataat cacaggcgct tcttcttcaa ttttcatttg tttgaagcgt tcagccagct
    17641 tttctggata atgttctttg aaataattga taccaaaaat ggtaacctca tccataggaa
    17701 gcaactgatc cttgatagct ccagtcaatg ccaacttaag tgcaacagtt tcatcctcaa
    17761 acttaggcca gagaatcccc ggtgtatcca agatttccag atctttattg gttttaagcc
    17821 attgttgacc ttttgtgacc cctggcttgt ttccaacaac agcaatcttt ttaccagcca
    17881 aacggttcat cagagtggat ttaccagcgt ttggaatccc gataatcatg gtacgcaagg
    17941 tttcaatctg aatcccacgt tctttctggc gagcaatctt atcagccatg agcttcttgg
    18001 ccgcatctgt tacaactttt acagtcactt gctctttgga gttgatagct agcgtctgga
    18061 ttccttgtga ttcaaaatac tgacgccatt ccttggtcat tgctggatca gccaagtcgg
    18121 ccttgtttaa aatcaagagt tttggtttat caccaacaat cttggtcaac ataggatttt
    18181 gactagatag aggcaagcgt gcatctacta aaatcgtcac aaaatcaaca aattttaaat
    18241 tctcctgcac ctgtcgacga gctttagaca tgtgaccagt aaaccattga atagtagcca
    18301 ttgagttttt tcctttcata gcaaggattt agatccccta ttttatttta ctatagtttg
    18361 aacatagaga gttttcaaat gaatgatgtc caaacagttc ttgttttatg acatagaaat
    18421 ctactttata ttatatcatg ccttctttat tttgtccgat gatagccttt taccctatct
    18481 tttaccctat accctatcct ataccctata tagaaaaaag ccatcaaatg atgacttttc
    18541 agagggagca aaaaactgtc ctctttatgt tttaaacatt
//
LOCUS       DBEJZV010000040        17575 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.40, whole genome shotgun sequence.
ACCESSION   DBEJZV010000040 DBEJZV010000000
VERSION     DBEJZV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.40"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(80..931)
                     /gene="srtC-3"
                     /locus_tag="ACL3S0_001786"
     CDS             complement(80..931)
                     /gene="srtC-3"
                     /locus_tag="ACL3S0_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-3"
                     /protein_id="HGR1312657.1"
                     /translation="MSKAKLQKLLGYLLMLVALVIPVYCFGQMVLQSLGQVKGHEIFS
                     ESVTADSYQEQLQRSLDYNQRLDSQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPS
                     LEIMEPVYLGADYHHLAMGLAHVDGTPLPVEGKGIRSVIAGHRAEPSHVFFRHLDQLK
                     VGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLV
                     NFERVAVYQKSDPQTAAVARVAFTKEGQSVSRVATSQWLYRGLVVLAFLGILFVLWKL
                     ARLLRGK"
     gene            complement(918..1811)
                     /gene="srtC-2"
                     /locus_tag="ACL3S0_001787"
     CDS             complement(918..1811)
                     /gene="srtC-2"
                     /locus_tag="ACL3S0_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-2"
                     /protein_id="HGR1312658.1"
                     /translation="MDNSRRSRKKGTKKKKHPLILLLIFLVGFAVAIYPLVSRYYYRI
                     ESNEVIKEFDETVSQMDKAELEERWRLAQAFNATLKPSEILDPFTEQEKKKGVSEYAN
                     MLKVHERIGYVEIPAIDQEIPMYVGTSEEILQKGAGLLEGASLPVGGENTHTVVTAHR
                     GLPTAELFSQLDKMKKGDVFYLHVLDQVLAYQVDQILTVEPNDFEPVLIQHGEDYATL
                     LTCTPYMINSHRLLVRGKRIPYTAPIAERNRAVRERGQFWLWLLLAALVMILVLSYGV
                     YRHRRIVKGLEKQLEEHHVKG"
     gene            complement(1798..2700)
                     /gene="srtC-1"
                     /locus_tag="ACL3S0_001788"
     CDS             complement(1798..2700)
                     /gene="srtC-1"
                     /locus_tag="ACL3S0_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-1"
                     /protein_id="HGR1312659.1"
                     /translation="MAKTKKQKRNNLLLGVVFFIGMAVMAYPLVSRLYYRVESNQQIA
                     DFDKEKATLDEADIDERMKLAQAFNDSLNNVVSGDPWSEEMKKKGRAEYARMLEIHER
                     MGHVEIPVIDVDLPVYAGTAEEVLQQGAGHLEGTSLPIGGNSTHAVITAHTGLPTAKM
                     FTDLTKLKVGDKFYVHNIKEVMAYQVDQVKVIEPTNFDDLLIVPGHDYVTLLTCTPYM
                     INTHRLLVRGHRIPYVAEVEEEFIAANKLSHLYRYLFYVAVGLIVILLWIIRRLRKKK
                     KQPEKALKALKAARKEVKVEDGQQ"
     gene            complement(3039..4190)
                     /gene="rrgC"
                     /locus_tag="ACL3S0_001789"
     CDS             complement(3039..4190)
                     /gene="rrgC"
                     /locus_tag="ACL3S0_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus minor pilin RrgC"
                     /protein_id="HGR1312660.1"
                     /translation="MCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQLPSRDGHRLQV
                     WKLDDSYSYDNRVQIVRDLHSWDENKLSSFKKTSFEMTFLENQIEVSHIPNGLYYVRS
                     IIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKADTVTTKVKLIKVDQDHNRLEGVGFKL
                     VSVARDGSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIVVTNLPLGTYRFKEVEPLAG
                     YTVTTMDTDVQLVDHQLVTITVVNQKLPRGNVDFMKVDGRTNTSLQGAMFKVMKEENG
                     HYTPVLQNGKEVVVASGKDGRFRVEGLEYGTYYLWELQAPTGYVQLTSPVSFTIGKDT
                     RKELVTVVKNNKRPRIDVPDTGEETLYILMLVAILLFGSGYYLTKKTNN"
     gene            4077..4310
                     /locus_tag="ACL3S0_001790"
     CDS             4077..4310
                     /locus_tag="ACL3S0_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312661.1"
                     /translation="MTRWQLTNHLLIVLQLQDQRVIFLRLDCMCTPYKRKTQSHNKED
                     TTNHFLHFLHFLHCHQWLLSLLLKQVDPHLCCF"
     gene            complement(4276..6273)
                     /gene="rrgB"
                     /locus_tag="ACL3S0_001791"
     CDS             complement(4276..6273)
                     /gene="rrgB"
                     /locus_tag="ACL3S0_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus major pilin RrgB"
                     /protein_id="HGR1312662.1"
                     /translation="MKSINKFLTMLAALLLTASSLFSAATVFAAGTTTTSVTVHKLLA
                     TDGDMDKIANELETGNYAGNKVGVLPANAKEIAGVMFVWTNTNNEIIDENGQTLGVNI
                     DPQTFKLSGAMPATAMKKLTEAEGAKFNTANLPAAKYKIYEIHSLSTYVGEDGATLTG
                     SKAVPIEIELPLNDVVDAHVYPKNTEAKPKIDKDFKGKANPDTPRVDKDTPVNHQVGD
                     VVEYEIVTKIPALANYATANWSDRMTEGLAFNKGTVKVTVDDVALEAGDYALTEVATG
                     FDLKLTDAGLAKVNDQNAEKTVKITYSATLNDKAIVEVPESNDVTFNYGNNPDHGNTP
                     KPNKPNENGDLTLTKTWVDATGAPIPAGAEATFDLVNAQTGKVVQTVTLTTDKNTVTV
                     NGLDKNTEYKFVERSIKGYSADYQEITTAGEIAVKNWKDENPKPLDPTEPKVVTYGKK
                     FVKVNDKDNRLAGAEFVIANADNAGQYLARKADKVSQEEKQLVVTTKDALDRAVAAYN
                     ALTAQQQTQQEKEKVDKAQAAYNAAVIAANNAFEWVADKDNENVVKLVSDAQGRFEIT
                     GLLAGTYYLEETKQPAGYALLTSRQKFEVTATSYSATGQGIEYTAGSGKDDATKVVNK
                     KITIPQTGGIGTIIFAVAGAVIMGIAVYAYVKNNKDEDQLA"
     gene            complement(6496..9156)
                     /gene="rrgA"
                     /locus_tag="ACL3S0_001792"
     CDS             complement(6496..9156)
                     /gene="rrgA"
                     /locus_tag="ACL3S0_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus tip adhesin RrgA"
                     /protein_id="HGR1312663.1"
                     /translation="MKKVRKIFQKAVAGLCCISQLTAFSSIVALAETPETSPAIGKVV
                     IKETGEGGALLGDAVFELKNNTDGTTVSQRTEAQTGEAIFSNIKPGTYTLTEAQPPVG
                     YKPSTKQWTVEVEKNGRTTVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDGSE
                     KNGQHKALNPNPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTVYEQKDKSVPL
                     DVVILLDNSNSMSNIRNKNARRAERAGEATRSLIDKITSDPENRVALVTYASTIFDGT
                     EFTVEKGVADKNGKRLNDSLFWNYDQTSFTTNTKDYSYLKLTNDKNDIVELKNKVPTE
                     AEDHDGNRLMYQFGATFTQKALMKADEILTQQARQNSQKVIFHITDGVPTMSYPINFN
                     HATFAPSYQNQLNAFFSKSPNKDGILLSDFITQATSGEHTIVRGDGQSYQMFTDKTVY
                     EKGAPAAFPVKPEKYSEMKAAGYAVIGDPINGGYIWLNWRESILAYPFNSNTAKITNH
                     GDPTRWYYNGNIAPDGYDVFTVGIGINGDPGTDEATATSFMQSISSKPENYTNVTDTT
                     KILEQLNRYFHTIVTEKKSIENGTITDPMGELIDLQLGTDGRFDPADYTLTANDGSRL
                     ENGQAVGGPQNDGGLLKNAKVFYDTTEKRIRVTGLYLGTGEKVTLTYNVRLNDQFVSN
                     KFYDTNGRTTLHPKEVEKNTVRDFPIPKIRDVRKYPAITIAKEKKLGEIEFIKINKND
                     KKPLRDAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRLFENS
                     EPAGYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREY
                     PRTGGIGMLLFYLIGCMMMGGVLLYTRKHP"
     gene            9667..11196
                     /gene="rlrA"
                     /locus_tag="ACL3S0_001793"
     CDS             9667..11196
                     /gene="rlrA"
                     /locus_tag="ACL3S0_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus transcriptional regulator RlrA"
                     /protein_id="HGR1312664.1"
                     /translation="MLNKYIEKRITDKITILNILLDIRSIELDELSTLTSLQSKSLLS
                     ILQELQETFEEELTFNLDTQQVQLIEHHSHQTNYYFHQLYNQSTILKILRFFLLQGNQ
                     SFNEFTQKEYISIATGYRVRQKCGLLLRSVGLDLVKNQVVGPEYRIRFLIALLQFHFG
                     IEIYDLNDGSMDWVTHMIVQSNSQLSHELLEITPDEYVHFSILVALTWKRREFPLEFP
                     ESKEFEKLKNLFMYPILMEHCQTYLEPHANMTFTQEELDYIFLVYCSANSSFSKDKWN
                     QEKKTHTIQLILQHTRGKHLLSKFKNILGNDISNSLSFLTALTFLTRTFLFGLQNLVP
                     YYNYYEHYGIESDKPLYHISKAIVQEWMTEQKIEGVIDQHRLYLFSLYLTETIFSSLP
                     AIPIFIILNNQADVNLIKSIILRNFTDKVASVTGYNILISPPPSEEHLTEPLIIITTK
                     EYLPYVKKQYPKGKHHFLTIALDLHVSQQRLIYQTIVDIRKEAFDKRVAMIAKKAHYL
                     L"
     gene            11461..12723
                     /locus_tag="ACL3S0_001794"
     CDS             11461..12723
                     /locus_tag="ACL3S0_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGR1312665.1"
                     /translation="MEHINHTTLLIGIKDKNITLNKAIQHDTHIEVFATLDYHPPKCK
                     HCKGKQIKYDFQKPSKIPFIEIGGFPSLIHLKKRRFQCKSCRKVTVAETTLVQKNCQI
                     SEMVRQKIAQLLLNREALTHIASKLAISTSTSTVYRKLKQFHFQEDYTTLPEILSWDE
                     FSYQKGKLAFIAQDFNTKKIMTILDNRRQTTIRNHFFKYSKEARKKVKVVTVDMSGSY
                     IPLIKKLFPNAKIVLDRFHIVQHMSRALNQTRINIMKQFDDKSLEYRALKYYWKFILK
                     DSRKLSLKPFYARTFRETLTPRECLKKIFTLVPELKDYYDLYQLLLFHLQEKNTDQFW
                     GLIQDTLPHLNRTFKTTLSTFICYKNYITNAIELPYSNAKLEATNKLIKDIKRNAFGF
                     RNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(12781..15105)
                     /gene="pflB"
                     /locus_tag="ACL3S0_001795"
     CDS             complement(12781..15105)
                     /gene="pflB"
                     /locus_tag="ACL3S0_001795"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGR1312666.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDKYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            15332..15463
                     /locus_tag="ACL3S0_001796"
     CDS             15332..15463
                     /locus_tag="ACL3S0_001796"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312667.1"
                     /translation="MEIEKQTRKLAAGCSKHCFEVVNRTDEVSSKHCFEVADRADGV"
     gene            15498..16559
                     /gene="dinB"
                     /locus_tag="ACL3S0_001797"
     CDS             15498..16559
                     /gene="dinB"
                     /locus_tag="ACL3S0_001797"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGR1312668.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPISIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYNLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TILSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(16706..17551)
                     /locus_tag="ACL3S0_001798"
     CDS             complement(16706..17551)
                     /locus_tag="ACL3S0_001798"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGR1312669.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
BASE COUNT         5203 a         3847 c         3028 g         5497 t
ORIGIN      
        1 agcttagctt tttttcaacc cactacagtt gacaaagagc cggaaaaagg aacagcctta
       61 gctttccttt catttctttt tatttccctc gtagtaaacg tgctagcttc cacaaaacaa
      121 acaggattcc cagaaatgcc agtaccacta gcccacggta caaccattga gaggttgcaa
      181 cacgcgatac agattgtcct tctttcgtaa aagcaaccct cgcaactgca gctgtttgtg
      241 gatctgattt ttgataaaca gcgactcgtt caaaattcac taataagcgt ttattaaagg
      301 taggaatcgg atcgcaggtt atcaaggtca tgatattttt agagctaacc gattctaatt
      361 tttcccattc cgacggtaaa ataatctctg tgtccatcat ctgatattct acaatttcct
      421 ggccattatc ataataaaga gcatctccaa cttttagctg atccaaatgg cggaaaaaga
      481 catggcttgg ttctgcacgg tgcccagcaa tcactgaacg aatccctttt ccctcaacag
      541 gaagaggcgt cccatccaca tgggccaacc ccattgctaa atgatggtaa tccgctccta
      601 gataaactgg ctccatgatt tccaaactcg gaatcgacaa atagccgtag actgcatcag
      661 gatcgtcaga cacttggtaa tttacctcat acccttccgc caaaaaagga tctacaatac
      721 gattttgcga atccaagcgt tgattgtaat caagcgaccg ttgcaattgc tcttggtaac
      781 tgtcggccgt cacagattct gaaaatatct catgaccttt tacttgtcct aaagactgta
      841 acaccatctg cccaaaacaa taaacaggaa tcaccaatgc taccagcatc agcaaatacc
      901 ctagtaattt ctgtagctta gcctttgaca tgatgctcct ccaattgttt ttctagccct
      961 ttgacaatgc gacgatgacg atacaccccg taactcaata ccagaatcat aaccaacgcc
     1021 gctagcaata accacaacca gaattgccca cgctctctca ccgctcgatt tcgctctgca
     1081 attggtgccg tatacggaat ccgcttccca cgtaccaaca gacgatgact gttaatcata
     1141 tacggtgtac aggtcaacaa ggtcgcataa tcttccccat gttgaatcaa gacaggctca
     1201 aagtcatttg gctcaaccgt caaaatctga tccacttggt aggccaacac ctggtctaaa
     1261 acgtgaagat aaaagacatc cccttttttc atcttatcca attgactaaa cagttctgcc
     1321 gtcggtaatc ctctatgagc agtgacaact gtgtgggtat tttcaccacc aaccggtaac
     1381 gaagctccct ctagcaatcc tgcgcccttc tgaagaattt cctcactcgt tccgacatac
     1441 atcggaattt cctgatcaat cgcaggaatt tccacatagc caatccgctc atggaccttt
     1501 agcatattgg catattctga gacgcctttc tttttctctt gctctgtaaa aggatcaaga
     1561 atttcagatg gtttcaaggt cgcattgaag gcttgagcca agcgccaacg ctcctcaagt
     1621 tctgccttat ccatctggga aaccgtctca tcaaactctt taataacctc gtttgactca
     1681 atacgataat aataacgaga caccaatgga tatatcgcaa cggcgaatcc tactaagaaa
     1741 atcagaagaa ggatcagcgg atgtttcttc ttttttgtgc ctttttttcg tgaacgtcta
     1801 ctgttgtcca tcctccacct tcacttcctt ccttgctgct ttcagcgcct tcaaagcctt
     1861 ttccggttgt tttttcttct tgcgcaagcg tcgaataatc cataaaagaa tcacaatcaa
     1921 accaactgcc acataaaaca ggtagcgata gagatgactg agtttgtttg ctgcaataaa
     1981 ttcttcctca acctctgcta cgtacggtat ccgatgcccc cgaaccaata gacgatgggt
     2041 attgatcatg tatggcgtac aagtcagcaa ggtcacataa tcatgacctg gtacaatcaa
     2101 taaatcatca aagttcgtcg gctcaatcac ctttacttga tccacttgat aggccatcac
     2161 ttccttgata ttgtgcacat aaaacttatc cccaacttta agtttggtca aatccgtaaa
     2221 catcttagct gttggcaaac ctgtatgtgc cgtaatcacc gcatgggtcg aattgcctcc
     2281 gatcggcaga gaagttccct ctagatgccc agccccttgc tgcaatacct cttcagcagt
     2341 accagcataa accggcaaat ccacgtcaat aacggggatt tccacatgcc ccatccgctc
     2401 atggatttct aacatacgtg catactctgc tcgccctttt ttcttcattt cttccgacca
     2461 aggatcgcca ctcactacat tattcaaaga gtcattgaag gcttgtgcca atttcattcg
     2521 ttcatcaatg tcagcctcat ccaacgttgc tttttcctta tcaaagtcag caatttgttg
     2581 atttgattcc actcgataat acaagcgaga caccagcgga tacgccatta ccgccattcc
     2641 aatgaaaaat accactccta ataggagatt gtttcgtttt tgcttttttg tttttgccat
     2701 tttttatcag cattccttta acttcaaact catcatttta tcgcttttcc taacagacaa
     2761 tcctatctgc taagagaaac gagaaaatct catttctttc tgattcacca tccattttaa
     2821 atcagaatcc cagtcctgtc cattcctaaa atgattacca gaccagtcct atcgttttac
     2881 aaacaataac ccacaatgag gctggcacaa tctgcccagc ctcatatccg ttattgtgat
     2941 tcatgccaaa tcaccatgat tcctgattaa catcacctca gagtactctg gtcttccctt
     3001 cagcctgcta tctttttcat aatgatgtac attgaatatc agttatttgt ttttttcgta
     3061 agataatagc cactaccaaa caacaaaatg gcaacaagca tcaagatata caaggtttct
     3121 tcccctgtat ctggcacatc aatccgtggt cgcttgttat ttttaaccac tgttaccagt
     3181 tccttacgag tatctttccc gattgtaaag gaaacaggcg atgttaattg aacataacca
     3241 gttggagctt ggagctccca taaatagtat gtcccatact ctagaccttc cactcggaaa
     3301 cgaccatctt tccctgatgc cacaactact tccttaccat tttgaagaac aggagtatag
     3361 tgtccgtttt cttctttcat gactttgaac attgcccctt gaagagaggt attggtccta
     3421 ccatccacct tcataaagtc aacattgcca cgtggtaatt tctgattgac aaccgtaatc
     3481 gtcaccagct gatgatctac caactggaca tccgtatcca tcgtcgtaac agtatagcct
     3541 gccagtggct ccacctcctt gaaacgatag gtcccaagag gaagatttgt cacaacaatc
     3601 tctccatttt tatcagtata gagagttcta cctacttgac cagaagaact gtaacggtat
     3661 tctccaatca agggaacctc tttttcagaa ccatctcttg ctactgatac caatttaaag
     3721 ccgacaccct ccaagcgatt gtggtcttga tccaccttta tcagcttcac ctttgttgtc
     3781 accgtatctg cttttttcgc tacaatgacc aaaggctcta ccgtctgatc tgtcatttca
     3841 aaaagaaatt cagctggata agaaaccgca tccgtctgga taatagagcg aacatagtaa
     3901 agaccatttg gaatatgaga tacttcaatc tgattctcaa ggaaggtcat ctcaaacgaa
     3961 gtctttttga aagaagaaag tttattctca tcccacgaat gcaagtctct cacaatttgc
     4021 acccgattat cataggaata cgaatcatcc aacttccata cctgcaaccg atgaccatca
     4081 cgagatggca attgactaac cacctcctga tagttctcca attgcaagac caacgtgtga
     4141 tcttcttgcg cttggactgc atgtgcaccc catacaagag aaaaacacag agccataaca
     4201 aagaagatac gactaatcat tttctgcatt ttctgcattt tctgcattgt catcaatggc
     4261 tcctttctct cttacttaag caagttgatc ctcatctttg ttgtttttaa catatgcgta
     4321 cactgcaata cccataatca cagcccctgc tacagcaaag ataattgtac caataccacc
     4381 cgtttgtggg atcgtgattt ttttgttgac tacttttgta gcgtcatctt tacctgaacc
     4441 agcagtatac tcaatgcctt gtccagtcgc tgaataagaa gttgcagtga cttcaaattt
     4501 ctgacgacta gttagtaatg cataaccagc aggctgtttt gtttcttcta agtaatatgt
     4561 acctgcaaga aggcctgtaa tttcaaagcg accttgtgca tcagaaacta atttcacaac
     4621 attttcattg tccttatctg ccacccattc aaatgcattg ttggcagcaa tcacagcagc
     4681 attataagca gcttgagctt tgtcaacttt ctctttttct tgctgagttt gttgttgtgc
     4741 agtaagagcg ttataagcag caactgctct atctaaagca tcctttgttg taacaaccaa
     4801 ctgcttctct tcttgactca ctttatctgc tttacgtgct aaatattgac cagcattatc
     4861 agcatttgca attacaaatt ctgccccagc taaacgatta tctttatcat taactttgac
     4921 aaacttttta ccatatgtaa caacttttgg ctctgttgga tcaagtggtt ttggattttc
     4981 gtctttccag ttcttgacag caatttctcc agctgtagtg atttcttgat aatctgctga
     5041 ataccctttt atactacgtt caacgaattt atattctgta tttttatcca atccgttaac
     5101 agtaactgta tttttgtctg ttgtcaaagt tacagtttgt acaactttac cagtctgagc
     5161 attaaccaaa tcgaacgttg cttcagctcc agccggaatt ggtgcacctg tagcatcaac
     5221 ccatgtcttg gtcaatgtca aatcgccgtt ttcatttggc ttattcggct ttggagtatt
     5281 cccgtgatct ggattattac catagttaaa tgttacatca ttagattctg gtacttctac
     5341 aattgctttg tcattcaatg ttgccgaata agtgattttc acagtttttt cagcgttttg
     5401 gtcattcact ttagctaaac cagcatctgt taatttcaaa tcaaaaccag ttgctacttc
     5461 tgttagagca taatcacctg cttcaagtgc aacatcatca acagttactt tcactgtacc
     5521 tttgttgaat gccaaacctt cagtcattct atcgctccag tttgctgttg cataattagc
     5581 aagtgctgga atttttgtaa caatttcgta ctctacaaca tctccaactt ggtggttcac
     5641 aggtgtatct ttatctacac gtggtgtatc tggatttgct ttacctttga aatctttatc
     5701 aatttttggc tttgcttctg tattttttgg atacacatgc gcatccacaa catcgttcaa
     5761 tggtaattca atttcaattg gaactgcttt agaacctgtt aaggttgctc catcttcacc
     5821 gacataagtt gataaactgt gaatttcata aattttatac ttagcagctg gtaaatttgc
     5881 cgtgttaaat ttagctcctt cagcttctgt taattttttc attgcagttg ccggcattgc
     5941 ccctgagagt ttaaatgttt gtggatcaat attcactcct agagtttggc cattttcatc
     6001 aataatttca ttattagtat ttgtccaaac gaacataaca ccggcaattt cttttgcatt
     6061 tgcaggtaga acacccactt tattaccagc atagttacct gtttctaact catttgcaat
     6121 tttatccata tccccatctg ttgccaatag tttatgaacg gtaacagatg ttgttgtcgt
     6181 cccagccgca aaaactgttg cagctgaaaa caggctactc gctgtcagta ataaggcagc
     6241 aagcattgtt aaaaatttgt tgattgattt catgatttct ccttatttat ctcttaaaat
     6301 caactgtgag caatgtaatg aattacacat gacaataata atcctttttc tgtgcaagtt
     6361 ttcgaaaaca tctccccttt caatggtggt ttacttggcg aagaaaactg gtttcaccaa
     6421 gtaaacttaa atctcttctt gagtgctact tcttaaaagt atcgttcaga acatagatat
     6481 tatcatttct acactttacg gatgtttccg tgtgtataat agaactcctc ccatcatcat
     6541 gcaacctatc agatagaata gcaacattcc gataccacca gttcgaggat attctctctt
     6601 tggaggaata ggttcattgg taatatagtg cttatcattc gtaaactcgt aacccgctgg
     6661 tatatcttgt ggaacgattg aagtcacatc tctgacttct ccatttacta tttggaaggc
     6721 aacgataggc ttattttgaa cgggtttata accagctggt tcagaatttt caaataatcg
     6781 atatttccca tctgacagat ttttaaaggt caacttacca tcttcacctg ttctcacatt
     6841 ttgataagtg ccattttgat caatagctcc ataaatatct ggataatccg gatgttgttt
     6901 ttgaagacta aagaccgcat ctctcagtgg ttttttatca ttcttattga tcttaataaa
     6961 ctcaatttca ccaagttttt tctcttttgc aatcgtaatt gctggatatt ttcgcacatc
     7021 acgaatctta ggaatcggga agtcgcgcac tgtgttcttt tctacttcct tagggtgtag
     7081 ggttgttcga ccattcgtgt catagaattt attgcttaca aattggtcat tcaagcgaac
     7141 attataagtc aatgtaactt tttcacccgt tccaaggtac aaacctgtta cacgaatcct
     7201 tttctcagtc gtatcataga acacttttgc attttttagc aagccaccat cattttgtgg
     7261 accacctaca gcttgtccat tctccaagcg actaccatcg tttgcagtta aagtgtaatc
     7321 tgctggatca aatcttccat ctgtgcccaa ttgcaaatca attaactcac ccatcggatc
     7381 tgtaatcgta ccattctcaa ttgatttctt ttcagttacg atggtgtgga aataacgatt
     7441 caactgttcc aatatttttg tcgtgtcagt aacattggta tagttttcag gtttactaga
     7501 aatactttgc ataaaactag tagccgttgc ttcatccgta ccaggatctc cgttaatacc
     7561 aatacctacc gtaaagacat catacccatc aggagcaata ttcccgttat agtaccatct
     7621 tgtagggtca ccatgattgg taattttagc agtattagaa ttaaacggat aagccagaat
     7681 actctctctc caattaagcc aaatatatcc accattaatt ggatcgccta taactgcata
     7741 accagccgcc ttcatttcag aatatttttc aggtttaact gggaaagctg caggagcacc
     7801 tttttcataa actgtcttat ctgtaaacat ctggtaactt tgcccatctc cgcgtacaat
     7861 tgtatgttct ccactagttg cttgcgtaat aaaatcactt aatagtattc catctttatt
     7921 aggagattta ctaaaaaatg catttagttg attttgatat gatggagcaa acgtagcatg
     7981 attaaaatta atcggatacg acatagttgg gacaccatcc gtaatatgga aaatgacttt
     8041 ttgactattt tgtctcgctt gttgtgtcaa aatctcatct gccttcatca aagctttctg
     8101 agtaaaagtg gcaccgaatt ggtacatcaa tctatttcca tcatggtctt ctgcctcggt
     8161 aggtacctta ttttttaatt ctacaatgtc attcttatca ttagtcagct ttaaataact
     8221 ataatctttg gtattggttg taaaactcgt ctgatcataa ttccaaaaaa gagaatcatt
     8281 caatcgtttt ccgtttttat ctgctacccc tttttctact gtaaactcgg tcccatcaaa
     8341 gatagtggaa gcataagtca caagcgctac cctattttct ggatcagatg taattttatc
     8401 aataagagaa cgtgtcgcct caccagctct ttccgcacgt cgagcattct tgtttcgaat
     8461 gttactcata ctatttgagt tatcgagcaa gataacgaca tccagcggca cagacttatc
     8521 tttttgttca tacactgttt tcccactaac cgtcaattcg attccatatt ggttatcatc
     8581 caaattattc acttgataaa ttctctttga aagtgtacct tctggaatca cacgttcata
     8641 tggattcgga ttcaacgcct tgtgctgtcc gtttttttcc gaaccatcta ccttaataat
     8701 ctgataaggt gtttgaacat ctggataagt ccctgtttgt ggatactggt cagatagagc
     8761 ctcttctcga ttttctacct gttcaccttg gacagtcgtc cgaccattct tctcaacttc
     8821 aacagtccat tgtttagtag agggtttata accaactgga ggttgggctt ctgtcaaagt
     8881 gtatgtccca ggttttatgt ttgaaaatat cgcttctcct gtttgcgcct ctgtcctttg
     8941 cgaaacagtt gtgccatccg tattgttttt caactcaaag acggcatctc ctagaagcgc
     9001 tcctccttcg cctgtctcct taatcactac ttttcctatc gctggactgg tttcaggcgt
     9061 ttctgctaaa gcaactatcg aagaaaaagc tgtcaactga gatatacagc acagtcctgc
     9121 aactgccttc tgaaatatct ttcttacttt tttcatgtgt gtctccctgt taagcattat
     9181 tcatagaaca agttaatcct tctatgattc ataggtactt tcaatctgta tacacgaaga
     9241 aacggattac ttatgttctg ataaaattta tctcactgag ttaatccgtt cactaacaaa
     9301 cgtagcaaaa gcgtataaaa gtgcgttata gctatcttct caacctggca atgacacact
     9361 tgtatacaat atagtatagt attactatta actatcctag tataaattaa aacaacttcc
     9421 atcacaatag atatttttat cacatatttt tttatagaac gacaatattt gataaaaaaa
     9481 tattttctaa taaaaaaaat aagccataaa actccaccaa tactcattac tatctttaaa
     9541 atgcctttta ttacatgctg ttttatcaat aaagtcggaa attccacaac ctttttgaca
     9601 agacaattag tttcttttgt attataataa ttaaaattat ctatatgcaa ctaagattcg
     9661 gtaactatgc taaacaaata cattgaaaaa agaattacag ataaaattac cattttaaat
     9721 atattattgg atattcggtc tattgaacta gatgaactgt ctactttaac ttcattacaa
     9781 tctaaaagtc tcctaagcat tttgcaggaa ttacaagaaa cattcgagga agagttgaca
     9841 tttaatttag atacgcaaca agttcaatta atcgaacacc attctcatca aacgaattat
     9901 tacttccatc agctttataa ccaatcaact attttaaaaa tactccgctt ctttctacta
     9961 caaggtaatc aaagctttaa cgaatttaca caaaaagagt atatttccat cgcaacaggc
    10021 taccgcgtac gacaaaagtg tggcttgtta ctacgttcag taggtttgga ccttgtgaaa
    10081 aatcaagtag ttggtcctga atatcgcatt cgttttttaa ttgcactcct ccagtttcat
    10141 tttggtattg agatttatga tttgaatgat ggaagtatgg attgggtcac acatatgatt
    10201 gtgcagtcta attctcaact cagtcatgaa ctgttagaaa tcacacctga cgagtatgtt
    10261 cattttagca tactagtggc actcacttgg aaacgtcggg aatttccact tgagttccct
    10321 gagtccaaag agtttgaaaa attaaaaaac ctctttatgt atccgatttt gatggaacat
    10381 tgccaaactt acttagagcc acatgccaac atgactttta ctcaggaaga actggattat
    10441 atctttttgg tttattgttc tgctaattct tcgttttcca aggacaaatg gaatcaagaa
    10501 aaaaagactc atactattca actgattctt cagcatacaa gaggaaagca tctactatcc
    10561 aagttcaaga atatcttagg aaatgacatt tcgaattctc tttctttttt aacagcactg
    10621 actttcttaa caagaacgtt tttgtttggt ttacaaaatc tagttcccta ttataattat
    10681 tacgaacatt atgggattga aagcgacaag ccactgtatc atatttcgaa agcaattgtt
    10741 caagagtgga tgactgagca gaagattgaa ggagttatcg accagcatcg gctgtacctt
    10801 ttctcactct acttgacaga aaccatcttt tcctcactac ctgctatccc gatttttatc
    10861 attttaaata atcaagcaga tgtaaactta ataaagtcca ttattttacg gaattttact
    10921 gacaaagttg cctctgttac aggatacaat attctaatta gtcctcctcc ttcagaggag
    10981 catttgacag agccattgat tattattaca acgaaagaat acctgcctta cgttaaaaag
    11041 cagtatccca aagggaaaca tcactttttg acgattgcct tagatttgca tgttagccaa
    11101 cagcgtctca tctatcagac aattgtagat atccgaaaag aggcttttga caaacgggtc
    11161 gcaatgattg ctaaaaaggc tcactatttg ttataagttc atcgtactgt ctacacacaa
    11221 aaaggggctt cctaagccat ctctattctt atccccatat ttcccagttt tgggtaaatc
    11281 tgaacagaaa aacacttctg ctctctagtt tctgctagtg aacaaaagtg ttttttctgg
    11341 ctctataatt tctgtagtgg gtaaatccca ctgtggagat tatagggctt tttgagtatc
    11401 aaaaaagtcc cataagactt ataatgaaaa gcgcctaaac aactcattag aaagtatctt
    11461 atggaacaca tcaatcatac cacattactc atcggaataa aagacaaaaa catcacctta
    11521 aataaagcca ttcagcacga tacccatatc gaagtcttcg ctacacttga ttatcaccca
    11581 cctaaatgta aacactgtaa aggaaaacaa atcaaatacg acttccaaaa gccttctaaa
    11641 atccctttta tcgagattgg tggtttccct agcctcattc atttgaaaaa gagacgattt
    11701 caatgcaagt cctgtcggaa agtcactgta gctgaaacaa ctctcgttca gaaaaattgc
    11761 caaatctcgg aaatggtgag acagaaaatt gcccaactcc tactcaacag agaggctctt
    11821 acacatatcg cttctaaatt agccatctct acctctacct ctaccgtcta tcgtaagctc
    11881 aagcaatttc atttccaaga ggattacacc actttgcctg aaatcctctc ctgggatgaa
    11941 ttctcctacc agaaggggaa attggctttc attgctcagg atttcaacac taagaaaatc
    12001 atgaccattc ttgataacag acgtcaaaca accatccgaa atcatttctt caagtactcg
    12061 aaagaagcta gaaaaaaagt taaagtcgtc actgttgata tgtctggaag ttatatccct
    12121 ctcattaaga aattatttcc caatgctaaa attgttctcg atcgtttcca cattgtccaa
    12181 cacatgagca gggctcttaa tcagactaga atcaacatca tgaagcaatt tgatgataaa
    12241 tctctggaat acagagctct taaatattac tggaaattta tcctaaaaga tagtcggaaa
    12301 ctctctctta agcctttcta tgctagaact ttcagagaga ccttaactcc tagggagtgt
    12361 ctgaagaaaa tctttactct agtacctgaa cttaaagatt actatgacct gtatcaacta
    12421 ctcctatttc atctacaaga gaagaatact gaccagtttt ggggcttaat tcaagacacg
    12481 ttacctcatc tcaaccgcac ctttaaaacc actttgagca catttatttg ctataaaaac
    12541 tacatcacta acgccattga attgccttat tctaacgcta aacttgaggc cactaacaaa
    12601 ctcatcaaag acatcaagcg caatgccttt ggttttcgga actttgaaaa cttcaaaaaa
    12661 cggattttca tcgctctgaa catcaaaaaa gaaaggacaa aatttgtcct ttctcgagct
    12721 tagcttttct tcaacccact acagttgaca aagagccctt tttattattc aagaacttga
    12781 ttagctcaat gcatccaagg cgtcatccat tgaaagaact tcgtggaaga cacgttgtgt
    12841 caattcagtt ttttgttctg gagtgaggta tttagtgttt acacagtatc cagagatacg
    12901 tacgataacg tcttcgcctg acatgatttt ttcgtaaaca tcgttcaagt ccataacgtt
    12961 caagttaacg tgttgtccac cgttttcgaa gtaaccatca aggattgtta ccaagttatc
    13021 aacttgttca tcacgagtct taccaagagc gcgaggtgat acttgtgtag tcaatgagat
    13081 accgtcagct gcataactaa agtcaaggct agaaagtgag ttcaagtttt gcaaccaacc
    13141 acctttagct ttgttagatg ggttagcacc tggtgagaag aattcaagtt tagacaagtt
    13201 cacagaacca tcttcgttga ggtatacacc tttgtgaact ggtgagttac cagtttgttt
    13261 agagtaagca acgttagatg tgattgtcaa aagtgatact gtagcttctg cgtctttgta
    13321 tagtttgtgg ctacgtagac gagttgtgta agcttcgatc aaccattctg ccaattcgtt
    13381 tgaacgtggg tcatcttcac cccagcgtgg gtagtcaccg attgtttcgt aatcgtagat
    13441 gtagccatct tcatcacgga ttggtttaac tgtagcgtat ttaatcgctg acaatgtatc
    13501 aacagtgtta gcaaatccac aaataccgaa tcccatgttg gcacgttgtt tagttggcaa
    13561 gaaggccatt tgaacagctt cgtagttgta cttatcagtc atgtagtgga tgatgttcaa
    13621 ggcatctacg taagtgtcag tcaaccagtc aagagatttt tcaaagttcg ctttaactga
    13681 ttcgaattca agaacttcgt cacgaatagg atcgatgtca aatactttgt agtctttgtg
    13741 aacatcgtcg taaccaccat tcaaaccagt aagaagggct ttaagaacgt ttacacgagc
    13801 accgaagtac tggatgttgt ggcgttgttc ttcattttct ggatcaagtg gagacacaca
    13861 gcatgagata cagctcattt caccatatcc gtctttagcc attgttgtta caccttcgta
    13921 ttggatagaa gagtgtttgt ggctcatgtg catacagtag cgacggaagt tgtatggcaa
    13981 tttgtcagtc caaagaactg tcaagtttgg ctctggagag ttaccgatgt tgtcaagagt
    14041 gttcaagaaa cggtagtcca tcttagtaac acggtgacga ccgtcgttac ccataccagc
    14101 catagaagtt gtgataaagg ttgggtcacc tgagtacaat tggtcataag cttttgtacg
    14161 agcaaattta actgtacgaa gtttcataac gaaatcatca acgaattctt ggatttctga
    14221 ttcagtaaat gtaccacgag caaggtcacg ttctgcaaag atgtccaata cgattggtac
    14281 acgacctaga gatgtagcag caccgttaat cacacggcag acagccatga aagcaatgtt
    14341 aacccattgg attgcttctt tcacgttcat cgctggtttg cgaacatcaa ccccgtaaag
    14401 gtcacccagg cgaacaactt gttgcaatgc ttggtattga aggtttactt cttcacgaag
    14461 acggattgtt tcttcatcga tttctttgat tgcattccag tcatttactt tttcttgcat
    14521 caagtagtct gcaccgtaaa gagcaagacg tgcgtaaaca ccgatgatac gtccgcgtga
    14581 gtatgcatct ggaagaccag ttacagtgtg tgcgtgacga gcgcgacgaa tatttgaagt
    14641 gtaggcacgg aaaataccgt cgttaactgt tgttacatat ttagtgaaga tttcgtgaac
    14701 agctgggtct ggttcgtatc cattttcttt caaagtagtt tcagccatac ggataccacc
    14761 ttttggcatg aagttcaatt tgaagagttc atcgttttgg ataccgaaga taacttcatt
    14821 ttctttgtcg ataaatccag cagggatatc agcgatagat gttggacgag tgtccattgg
    14881 gaaacgagtt tcttcgtagt gtgctttagt ttcttctaca attttcttga tgtgaagtga
    14941 acgctctgtt ggtcctgcaa ggaagctttc gtctccatca taaggtgtgt agttagcttg
    15001 tacaaagcgt gatacacttg ctttttcttt ccaatctacg cctttgaagc cttcccaagc
    15061 tttgtcaaaa atatcttgtg cttcaacaac tgtcttaaca accatattaa tgtcctcttt
    15121 tttctagtaa cagtcatctg ttacattcat gagacaagta taccatatag taaccgattt
    15181 caacaagtga aaaatcccta tttttaaact ttcttttcta aaacagtcta tattttattt
    15241 caaactgtat tatatttttg aaaaaataaa gtcctttttt ctttttttca gaaaaaaggg
    15301 tataataaaa gaaaataagc agtaacactc aatggaaatc gaaaagcaaa ctaggaagct
    15361 agccgcaggc tgctcaaagc actgctttga ggttgtaaat agaactgacg aagtcagctc
    15421 aaaacactgt tttgaggttg cagatagagc tgacggggtt tgaagagatt ttcgaagagt
    15481 ataaaaaggt gctaggcatg ttgatttttc ctttgttaaa tgatttgtca agaaaaatca
    15541 tccatattga catggatgcc ttttttgctg cggtggaaat caaggataat cctaaactca
    15601 gaggaaaacc tgtcattatt ggaagcgacc ctcgacaaac aggtgggcgg ggagtcgttt
    15661 ctacctgtag ctatgaggct cgagcttttg gtgtccattc tgccatgagt tccaaggaag
    15721 cttatgaacg ttgtccccag gccgtcttta tctcaggaaa ttatgagaaa tacaaagctg
    15781 tgggactcca gattcgagct atttttaagc gctatacaga tttgattgaa cccataagta
    15841 ttgacgaagc ctatttggat gtgacagaaa ataaactcgg tatcaagtca gcggtcaaaa
    15901 ttgctcgcct cattcaaaaa gatatctggc aagaactcca tctaactgct tctgccggta
    15961 tttcctataa caagttctta gctaaaatgg cgagtgatta tcaaaaacct catggtttga
    16021 cagtgattct acctgaacag gctgagaatt ttctcaaaca aatggatatt tccaaatttc
    16081 atggagtagg aaaaaagaca gtagaacgtc ttcatcaaat gggcgttttt actggtgctg
    16141 atttacttga agttcctgag gtgaccctaa tagaccgttt tggtagacta ggctataatc
    16201 tgtatcgaaa ggctcgtggc attcacaact ctccagtcaa atccaatcgc atccgtaaat
    16261 caatcggcaa ggagaaaacc tacgggaaga ttctccgtgc tgaggaagat atcaaaaaag
    16321 agctgactat tctatcagaa aaagtcgctc tcaatctaca tcaacaagaa aaagctggaa
    16381 aaattgtcat tttgaaaatc cgctacgagg acttttcaac tcttaccaaa cgaaaaagtc
    16441 ttgctcaaaa aacacaagat gctagtcaga taagccaaat agccctgcaa ctctatgaag
    16501 aattaagcga gaaagaaaga ggtgtccgcc tattggggat taccctgact ggattttaaa
    16561 gctcaatgaa aatcaaagag caaactagga agctagccgc aggctgctca aaacactgtt
    16621 ttgaggttgc agataaagct gacgcggttt gaagagattt tctaagagta taaaaccttg
    16681 aagagttgcc ccttcaaggt ttttcttata caaataaacg gacaaaactg taaagtagca
    16741 aaacactacc aagcacgata cggtatttac caaaaagggt gaagtcgtgt tttttcacat
    16801 agctggtcaa gaagcgaata gccaccatgc tgaccgcaaa agctactccc atcgcgacca
    16861 agagcaaaaa caattgccca aagctcaaga gttctccggc tttcacaaat ttgaaaatct
    16921 ttaaggcact agctccaaac ataacaggaa tcccaagata gaaggtaaat tctgtcacaa
    16981 ctgaacgact ggttccattt aacaaaccac cgacaatcgt tgcacctgaa cggctagtcc
    17041 ctggtaaaag agcaagaact tggaagagtc cgatatagaa agcggtcgta taaggaagct
    17101 tgtccaactc tgttacactt ggctcgatag cacgcgcttt attgcgcttt tccaaataga
    17161 tgaaggcaac cccgtagata atcaacatga gagcaactga aaccatgtta tggaagtggg
    17221 tatcaaacca atcatcaaat ttaaagacac caagtaaagg caaagtggca atcaagacct
    17281 tcaaccatag tctccaagtc ttacgaactt cctgtttgtc cttagtcggt ttaaaaggat
    17341 tgagcttgtt aaaataaatc accataactg ctaaaatagc accaagctga attacgacat
    17401 taaacatgga cataaaggct tcattttgat tttggtattg gataaactcc tctgctaaaa
    17461 tcaagtgacc tgtactggaa atcggcaacc attccgtaat tccttcaaca atcccgaaga
    17521 agatagattt taaaatttca ataagataca tagatttctc cttatattat attta
//
LOCUS       DBEJZV010000041        17418 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.41, whole genome shotgun sequence.
ACCESSION   DBEJZV010000041 DBEJZV010000000
VERSION     DBEJZV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.41"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            222..1667
                     /locus_tag="ACL3S0_001799"
     CDS             222..1667
                     /locus_tag="ACL3S0_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGR1312670.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVYFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLMSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEHPDYASKIKKIYTKGFTKKVEAP
                     KTSKDQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVYNDQ
                     DFTSLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDHDRGRNQQKVIAAILQKLTSS
                     EALKNYSRIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGMGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDMLEGR"
     gene            1669..2400
                     /gene="cps4B"
                     /locus_tag="ACL3S0_001800"
     CDS             1669..2400
                     /gene="cps4B"
                     /locus_tag="ACL3S0_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGR1312671.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTSDVLDKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELINMGCYT
                     QVNSSHVLKSKLFGERYKFMKKRAQYFLERDLVHIIASDMHNVDSRPPHMAEAYDLVS
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            2409..3101
                     /gene="cpsC"
                     /locus_tag="ACL3S0_001801"
     CDS             2409..3101
                     /gene="cpsC"
                     /locus_tag="ACL3S0_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HGR1312672.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKHKLIILLVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDVLEKVATNLKLD
                     IPAKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIIAVTRVSDVT
                     TLEEARPAMTPSSPNVRRNTLVGFLGGAAVTVITVLLIELLDTRVKRPEDVEDVLQMP
                     LLGVVPDFDKMK"
     gene            3111..3800
                     /locus_tag="ACL3S0_001802"
     CDS             3111..3800
                     /locus_tag="ACL3S0_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HGR1312673.1"
                     /translation="MPTLEISQAKLELVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     AGEGKTTTSTNIAWAFARAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIVVDTPPVGVVI
                     DAAIIMQKCDASILVTKAGETKRRDLQKAKEQLEQTGKSCLGVVLNKLDTSVEKYGSY
                     GSYGNYRKQKK"
     gene            3815..5176
                     /locus_tag="ACL3S0_001803"
     CDS             3815..5176
                     /locus_tag="ACL3S0_001803"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR1312674.1"
                     /translation="MSEKLAKPSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYVLNPFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRIIDIVGSLVGLILCG
                     LVSIVLVPLIRKDGGSAFFAQTRIGKNGRHFTFYKFRSMCVDAEEKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     gene            5182..5925
                     /locus_tag="ACL3S0_001804"
     CDS             5182..5925
                     /locus_tag="ACL3S0_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HGR1312675.1"
                     /translation="MNERIQILGITIDPLTMKETVDAVEQYVLKKHPLHLMGVNADKI
                     NQCYEDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMKHLLELSNEKG
                     YSVYFFGAKEDVLQDMLKIFEERYPALNVVGYRNGYFSPEDEKHIQEDIKEKKPDFVF
                     VGITSPKKEYIIQSFMDNGINAVFMGVGGSFDVLSGHIKRAPLWMQNAHLEWLFRVAN
                     EPKRLFKRYFVGNVSFIRKVLRAKRGYKL"
     gene            5922..6746
                     /locus_tag="ACL3S0_001805"
     CDS             5922..6746
                     /locus_tag="ACL3S0_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HGR1312676.1"
                     /translation="MNQTEIVKLIQKVELDAIKEFQKICKENNIDFFLRGGSVLGAVK
                     YDGFIPWDDDMDIAVPREGYDKLPGIFKDRIIAGKYQVLAYQYCDTLHCYFPRLFLLE
                     DERKRLGLPRNTNLGLHLIDIIPLDGAPNHSFLRKLYFGKVYWYRFLASLGTTYVGDH
                     VDMHSAKQKLIIGFFKKLGFAKLFPQNYVYRRLDNLYKKYDWKKQKYAGTINASLFAK
                     EVMPVEIWGEGVEKPFEDAFFKVPTEYDRYLKRLYGENYLHEEPSDDEKKSHLGGQ"
     gene            6748..7626
                     /locus_tag="ACL3S0_001806"
     CDS             6748..7626
                     /locus_tag="ACL3S0_001806"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR1312677.1"
                     /translation="MFCYIILHYKVLEETISCVKSIKEGNSNTKQIVIIDNFSNNGTG
                     EKLQELYESDSEIDVLINHENAGFARGNNVAYQFAKEKYKPDFMVIMNNDIEIETEEF
                     EKIVTDIYRKEKFHLLGPDIFSTTYQLHQNPKRLTHYTYEEVKALNEKFKKGSQVSLA
                     LKIKCWLKSSKVLRTAIYQNRRKKKSVDYRKQVENPILHGSFIVYSRDFIEKEEYAFN
                     PNTFFYYETEILDYEAELKGYKRIYTPKIKVLHHQNVATNQVYTNLVEKTLFSNKCNF
                     ESTSYFLKLMKENEGV"
     gene            7627..8961
                     /locus_tag="ACL3S0_001807"
     CDS             7627..8961
                     /locus_tag="ACL3S0_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HGR1312678.1"
                     /translation="MTYLFLLCLTLFLLTFFYFFAFNQDLIAPPVVMSVMFLISSVFA
                     LINVQNWNIEYSGLAYLLIISGIIVFSMPLLALNSPSLNTKIKVTDRLIDIQFWKIAL
                     TIIVDLVILYLYRREIHNLALSHGYTGSNFQWFFRNATSYEGELTVRTSIRVLIRIID
                     VSAYIFGYTFINNFFIYSHKRSKDLLLLVPFLIFISKTLLSGGRLDIIKILIAYVVMA
                     YIQQKRKVGWDKVISHKYMRLGFVGLIAGIPTFYYSLFLSGRSTTRTVFESISTYLGG
                     SIQHFNQYIQNPIGVAEVFGDESFVAIMNILGNLGFVNYNSTVHLEFRQLGITMGNVY
                     TFFRRPWHDFGLVGMYIFSFVVGVFFAIFYLKLRKSRAGFKLDIHTIIYSYFFYWIFL
                     SSIEQYSFTTISLFTLVFIVLVYLMAFFYWNLDFHRGKLVIKLSDTSIKSEN"
     gene            8989..10413
                     /locus_tag="ACL3S0_001808"
     CDS             8989..10413
                     /locus_tag="ACL3S0_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312679.1"
                     /translation="MNSKIKNILTNFSYVISSNLLTVLTSSLVVLIFPKLMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYNNLDRKQFYSQMILFSSFLMIISLLLF
                     GLNVLAVTDSNARYIYNMTIISMIITNLRTLYVYVLQMTNRLKDSSIILLSDRVLYVL
                     LLFLFIVFGWHEYKVMILADILGRSFSLILSFWICKDIVFQPLSKFIFNIKESFDNIR
                     VGINLMLSNIASSLIIGIVRLGIQWNWNIETFGKVSLTLSVSNLLMTFINAIGLVVFP
                     LLRRTKAENLPKIYSNLRNVLMLIMFAILLIYYPLKIVLDLWLPAYQDALIFMTLIFP
                     MSVYEGKMALVINTYLKALRMERDILRVNALVMLISMGVTLVTTYLLNSLELTVVSIV
                     VLLALRSIIAELILSKKLDVSVKKDIVLEFLLTLVFISSSWYLPIGLAVIVYTIAYGL
                     YLYLKHEDIKTYLAYFKASKKTSN"
     gene            10478..11566
                     /gene="wecB"
                     /locus_tag="ACL3S0_001809"
     CDS             10478..11566
                     /gene="wecB"
                     /locus_tag="ACL3S0_001809"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-hydrolyzing UDP-N-acetylglucosamine
                     2-epimerase"
                     /protein_id="HGR1312680.1"
                     /translation="MKKIMLVFGTRPEAIKMCPLVNELKKHEDMETIVCVTGQHKEMV
                     SPVLDLFGVVPDYDLEIMKANQTLFSITTSILEKIKPVLEKEQPDIVLVHGDTTTTYA
                     AALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIATYHFAPTELAKENLLKE
                     GRENVYVTGNTVIDALTTTVQEDYTHTHLDLNANNRLILLTAHRRENLGEPMRHMFRA
                     VKRVLNEYEDVKVIYPIHKNPLVRETAAEIFGDTERIQIIEPLDVLDFHNFMNQSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEETIYQNFKLLLDDSG
                     EYKKMSQASNPYGNGDASQQIVQILRGI"
     gene            11729..12598
                     /gene="rfbA"
                     /locus_tag="ACL3S0_001810"
     CDS             11729..12598
                     /gene="rfbA"
                     /locus_tag="ACL3S0_001810"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGR1312681.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKQIKPSARGELEITDVNKAYLNRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEISYRMGYISREDVLELAQPLKKN
                     EYGQYLLRLIGEA"
     gene            12599..13192
                     /locus_tag="ACL3S0_001811"
     CDS             12599..13192
                     /locus_tag="ACL3S0_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HGR1312682.1"
                     /translation="MSDNFFGKTLVVRKIDAIPGLLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAAGKLQNNVSFSRKNVLRGLHAEPWDKYISVADDGKVLGSWVDLREG
                     ETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPALGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL"
     gene            13204..14253
                     /gene="rfbB"
                     /locus_tag="ACL3S0_001812"
     CDS             13204..14253
                     /gene="rfbB"
                     /locus_tag="ACL3S0_001812"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGR1312683.1"
                     /translation="MTEYKKIIVTGGAGFIGSNFVHYVYNNFTDVHVTVLDKLTYAGN
                     RANIEEILGDRVELVVGDIADAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDLRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQVGETYLIGADGEKNNKEVLELILKEMGQPAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQDWWKAEKE
                     AVEANYAKTQEIITV"
     gene            14319..15170
                     /gene="rfbD"
                     /locus_tag="ACL3S0_001813"
     CDS             14319..15170
                     /gene="rfbD"
                     /locus_tag="ACL3S0_001813"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGR1312684.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTENVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            15233..16329
                     /gene="glf"
                     /locus_tag="ACL3S0_001814"
                     /pseudo
     CDS             15233..16329
                     /gene="glf"
                     /locus_tag="ACL3S0_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272499.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(16533..17418)
                     /locus_tag="ACL3S0_001815"
                     /pseudo
     CDS             complement(16533..17418)
                     /locus_tag="ACL3S0_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5451 a         2882 c         3686 g         5399 t
ORIGIN      
        1 ttagattgaa actagaatag tacacctctg cttctaaaac attgttagaa atcgatttga
       61 ctgtcctgat cgatttgtca tgttcttatt tcattttact atatttttgt ttcgcgggaa
      121 gtctactaag atacttaaag atgcagatag taaaaaaaaa tgtagacatt accgtaaaaa
      181 agtgatataa tcgtatgatg ttcaaggtat aggtgttaat catgagtaga cgttttaaaa
      241 aatcacgttc acagaaagtg aagcgaagtg ttaatatcgt tttgctgact atttatttat
      301 tgttagttta ttttttattg ttcttaatct ttaagtacaa tatccttgct tttagatatc
      361 ttaacctagt ggtaactgcg ttagtcctac tagttgcctt ggtagggcta ctcttgatta
      421 tctataaaaa agctgaaaag tttactattt ttctgttggt gttctctatc cttgtcagct
      481 ctgtgtcgct ctttgcagta cagcagtttg tgggactgac caatcgttta aatgcgactt
      541 ctaattactc agaatattcg atcagtgttg ctgttttagc agatagtgag attgagaatg
      601 ttacgcaact gatgagtgtg acagcaccga ctgggactga taatgaaaac attcaaaaac
      661 tactagctga tatcaaatca agtcagaata ccgatttgac ggtcaatcag agttcgtctt
      721 acttggcagc ttataagagt ttgattgcag gagagactaa ggccattgtc ttaaatagtg
      781 tctttgaaaa tatcatcgaa tcggagcatc cagattacgc atcgaagata aaaaagattt
      841 ataccaaggg attcactaaa aaagtagaag ctcctaagac gtctaaggat cagtctttca
      901 atatctatgt tagtggaatt gatacttatg gtccgattag ttcggtgtcg cgttcagatg
      961 tcaatatcct gatgactgtc aatcgagata ccaagaaaat tctcttgacc acaacgccac
     1021 gtgatgctta tgtaccaatc gcagatggtg ggaataatca aaaagataaa ttgacccatg
     1081 cgggcatcta tggagttgat tcgtccatcc acactttaga aaatctctat ggagtggata
     1141 tcaattacta tgtgcgattg aacttcactt ctttcttgaa attgatcgat ttgttgggtg
     1201 gggtagatgt ttataatgac caagatttta catctctaca cgggaagttc catttcccag
     1261 ttggaaatgt ccacttagat tctgagcagg ctctgggatt tgttcgtgag cgctattccc
     1321 tagcggatgg tgatcatgac cgcgggcgca atcaacaaaa ggtgattgcg gccatccttc
     1381 aaaaattaac ttcgagcgaa gcgctgaaaa attatagtag gatcattgat agcttgcaag
     1441 attctatcca aacaaacatg ccacttgaga ccatgataaa cttggtcaat gctcagttag
     1501 aaagtggtgg aacgtacaaa gtgaattcgc aagacttgaa gggtatggga cggacggatc
     1561 ttccttccta tgcgatgcca gatagtaacc tctatatgat ggaaattaac gacagtagcc
     1621 ttgcatctgt caaaactgct attcaggata tgttggaggg cagatgaaat gattgatatt
     1681 cattcgcaca tcgtctttga tgtagatgat ggtcccaagt caagagagga aagcaaggct
     1741 ctcttggcag aatcctacag gcagggggtg cgaaccattg tctctacctc tcaccgtcgc
     1801 aagggcatgt ttgaaactcc ggaagagaag atagcagaaa actttcttca ggttcgggaa
     1861 atagctaagg aagtggcgag tgacttggtc attgcttacg gggctgaaat ttactacaca
     1921 tcagatgttt tggataagct ggaaaaaaat cggattccga ccctcaataa tagtcgttat
     1981 gccttgatag agtttagtat gaacacccct tatcgcgata ttcatagtgc cttgagtaaa
     2041 atattgatgt tgggaattac tccagtcatt gcccacattg agcgctatga tgcacttgaa
     2101 aataatgaaa aacgcgttcg agagctgatc aatatgggct gttacacgca agtaaatagt
     2161 tcacatgtcc tcaaatccaa actttttgga gaacgttata aattcatgaa aaaaagagct
     2221 cagtattttt tggagcgtga cttggttcat atcattgcaa gtgatatgca taatgtggac
     2281 agcagacctc cccatatggc agaagcatat gaccttgttt cccaaaaata cggagaagcg
     2341 aaggctcagg aactttttat agataatcct cgaaaaattg taatggatca actaatttag
     2401 gagaaatgat gaaagaacaa aacacgatag aaatcgatgt atttcaatta cttaaaacct
     2461 tgtggaaaca caagctaata attttattag tggcacttgt gacaggggcg ggagcttttg
     2521 catatagcac ttttattgtt aagccagaat atacaagcac cacgcgtatt tacgtagtca
     2581 accgtaatca aggagataag ccgggactga cgaatcagga cttgcaggca ggaacttatc
     2641 tggtaaaaga ctaccgcgaa attatccttt cgcaagatgt attggaaaag gtagcgacaa
     2701 atttgaaatt ggatattcca gcaaaaacgt taactagcaa agtgcaagtg actgtaccag
     2761 ccgacactcg tatcgtctca atctctgtca aggataaaca accagaggaa gccagtcgca
     2821 ttgctaattc tctacgagaa gttgctgcag aaaagatcat cgctgtaacg cgagtatctg
     2881 atgtaacgac gcttgaagaa gcgcgaccag ctatgactcc ctcttctcca aatgttcgac
     2941 gcaacacctt agttggtttt cttggaggag ccgccgtaac agtaattact gttcttttga
     3001 ttgagttgct cgatacccgt gtaaaacgtc ctgaagatgt tgaagatgta ctgcaaatgc
     3061 cacttctagg agtcgttcca gattttgata aaatgaaata ggaggaagtt atgccaacgt
     3121 tagaaatctc acaggcgaaa ttagaacttg tgaaaaaggc agaggaatat tataatgctt
     3181 tgtgcacgaa cctacagtta agtggagatg atttgaaagt attttctatc acttctgtga
     3241 aagcaggaga aggaaaaaca acgacttcca ccaatatcgc ttgggctttt gcgcgtgcag
     3301 gttacaaaac gcttctgatt gatgcagaca tgcgtaactc cgttatgtca ggtgtcttta
     3361 aatcaaggga aaggattact ggactaacag aatttctatc agggacaaca gacctgtcac
     3421 aggggctttg cgataccaat attgagaatc tctttgtgat tcaggctggc tctgtgtcac
     3481 caaatccgac agcccttctt caaagtaaga atttcagtac aatgcttgaa accttgcgta
     3541 aatattttga ctatatcgtc gtagacactc cccctgtcgg tgtcgtgatt gatgcggcta
     3601 tcattatgca gaaatgtgat gcttctattt tagtgacgaa ggcaggtgaa acaaaacgac
     3661 gggatcttca aaaagcgaaa gaacagttgg aacaaactgg gaagtcatgt ttaggagttg
     3721 tgttgaataa actcgatact tcagtagaga aatacggttc ttatgggagt tatgggaatt
     3781 acaggaaaca gaaaaaatag gttgagggat agaaatgagt gaaaaactag caaagccttc
     3841 agtagccata gtccagagtt ttcttgttat tttattgact tatctactta gcgctgtgag
     3901 agaaacagag attgtttcaa caacagctat tgtactttat atcctccact attttgtctt
     3961 ttatatcagt gattatggac ggaatttctt taaaagggga tatttgattg aacttgtcca
     4021 gacattgaaa tatatcctat tctttgcgct agcgattagt atttctaatt ttttcttaga
     4081 agatcgattt agtatttcca gaagaggcat gatttacttc ctcttattac atgttttctt
     4141 agtctatgtg ctaaacccat ttatcaagtg gtattggaag cgggcttatc ccaactttaa
     4201 aggaagtaag aagattctcc tacttacagc aacttctcgt gttgaaaagg tactggatag
     4261 attaatagaa tcaaatgatg ttgttgggga gttggtagcc gtcagtgttt tagataaacc
     4321 agattttcag catgatgatt taaaggttgt agcagagggg gagatagtaa attttgcgac
     4381 tcatgaggtg gtcgatgaag tctttatcaa tcttccaagt gaaaaataca atattggaga
     4441 gcttgtctct cagtttgaaa cgatgggaat tgatgtaaca gtcaatctaa atgctttcga
     4501 ttgggcacgt aacaagcaaa tttgtgagat ggcaggacta aatgttgtga ctttttctac
     4561 aacattttat aagactagcc atgtgattgc taagcggatt attgatattg tcggttccct
     4621 ggtaggtttg atattatgtg gtctagtcag tattgtgctg gttcctttga ttcgaaagga
     4681 tgggggttct gctttttttg ctcagacgcg tataggaaaa aatggccgcc attttacttt
     4741 ttataagttt cgctctatgt gtgtggatgc tgaggagaaa aaaagagaac tcatggaaca
     4801 aaataccatg cagggtggaa tgtttaaggt ggacgatgat cctcgtatca cgaaaattgg
     4861 tcattttata cggaagacga gcttggacga gctaccacag ttttataatg ttctaaaggg
     4921 agatatgagt ttggtaggta cacgaccacc aacagtggac gagtatgagc actatacccc
     4981 agaacaaaaa cgtcgcctaa gttttaaacc tggcataaca ggtttatggc aggtcagcgg
     5041 acgaagtgaa atcaaaaatt tcgatgaagt tgtcaaatta gatgtggcct atattgatgg
     5101 ttggacaatc tggaaagata ttgaaatttt attgaagaca gttaaggttg tattgatgaa
     5161 ggatggagcg aaatagttca tatgaatgag agaattcaaa tattaggaat tactatagat
     5221 ccattaacga tgaaagaaac agtggatgct gttgaacagt atgttttaaa gaagcaccct
     5281 ttgcacttga tgggagttaa cgcggataaa attaatcagt gctatgaaga tgagaaaatc
     5341 aaaaaaatcg ttaatgaatc aggaataatt aatgccgacg gtgcttcagt agttttagcg
     5401 agtaagtttt taggaacacc agttcctgag cgagttgctg gaatagactt gatgaaacat
     5461 ttactagagt tgtctaatga aaaaggatac tcggtctact tttttggagc aaaagaagac
     5521 gttttacaag atatgttaaa aatttttgaa gaaagatatc cagctctaaa tgttgttggc
     5581 tatagaaatg gatatttttc gcctgaagat gaaaaacata ttcaggaaga tattaaagag
     5641 aaaaaaccag attttgtgtt tgtaggaatt acttctccta agaaagaata tattatccaa
     5701 tcattcatgg ataatggaat taatgctgtg tttatggggg ttggtggaag ttttgatgta
     5761 ctatcagggc atatcaaacg agctccatta tggatgcaaa atgctcacct agagtggttg
     5821 tttcgtgtgg caaatgagcc taaacgtctc tttaagcgtt attttgtagg gaatgtttca
     5881 tttataagaa aagttttaag agcgaaaagg ggatataaac tttgaaccaa acagaaatag
     5941 ttaaattgat tcagaaagtt gaattggatg ctataaaaga gtttcaaaaa atttgtaaag
     6001 agaacaatat agatttcttc cttcgtgggg ggagtgtact tggggcagtc aaatatgatg
     6061 gctttattcc atgggatgat gacatggata ttgctgtgcc tcgtgaaggc tacgataaac
     6121 ttccaggtat ctttaaggat agaattatcg caggcaaata tcaggttctt gcttatcaat
     6181 attgcgatac tttacattgc tactttcctc gcttattcct tttagaagat gaaagaaaac
     6241 gtttgggatt gccacgaaat accaatttag gtttgcattt gattgatatc attcctttgg
     6301 atggtgcccc aaatcattca tttttaagaa agctttactt cggtaaagta tactggtatc
     6361 gttttttagc aagtttagga actacctatg ttggagacca tgtggatatg cattccgcta
     6421 agcaaaaact aatcattggt ttctttaaaa agctaggatt tgcaaaacta ttccctcaaa
     6481 attatgtgta cagacgcttg gataatctct ataaaaagta tgattggaaa aagcagaagt
     6541 atgctgggac aattaatgca tctctgtttg ccaaagaagt catgccagta gagatttggg
     6601 gagaaggagt agagaagcct tttgaggatg ccttctttaa agttcccacg gagtatgacc
     6661 gctatctgaa aagactttac ggagaaaact atcttcacga agagcctagt gatgatgaaa
     6721 agaaatcgca tttaggagga caataatttg ttttgttata ttattttgca ttacaaagtc
     6781 ttagaggaaa ctatttcttg tgttaaatca ataaaagaag gcaattccaa tacaaagcag
     6841 atcgttatta ttgataattt ttctaataac ggtacgggtg aaaaactaca agagctgtat
     6901 gagtcagatt cagagattga tgtcttgatt aaccatgaaa atgctggttt cgctcgaggt
     6961 aataatgtag catatcagtt tgctaaggaa aagtacaaac ctgattttat ggttatcatg
     7021 aataatgata ttgagataga aacagaagag tttgaaaaaa tcgtgacaga tatctatcgg
     7081 aaggaaaaat tccatttgtt aggaccagat atcttttcga cgacgtatca gcttcaccaa
     7141 aacccaaaac ggttgacgca ttatacttat gaagaggtta aggctctcaa tgaaaaattt
     7201 aagaaaggga gccaagttag tctagcatta aaaattaaat gttggttgaa gtctagtaaa
     7261 gttcttcgga cagcaatcta tcaaaatagg cgtaaaaaga aatcagtaga ctatagaaaa
     7321 caggtagaaa acccaattct tcatggttcg tttattgtat attctagaga ttttattgag
     7381 aaagaggagt atgcttttaa tcccaatacc ttcttctatt atgaaacaga gatattagat
     7441 tatgaagctg agttaaaagg atataagaga atttatacac cgaagattaa ggtcttgcac
     7501 catcaaaatg ttgcaaccaa tcaagtctat acaaacttag tagaaaaaac cttgttttca
     7561 aacaaatgca actttgaatc cactagttat tttttgaagt tgatgaaaga aaacgagggt
     7621 gtgtaaatga cttatttatt tttactctgc ctgaccttat tcttattaac tttcttctat
     7681 ttttttgctt tcaatcaaga tttgatagct ccgccagttg tcatgtctgt tatgtttctc
     7741 attagttctg tatttgccct tattaatgtg caaaactgga atattgagta tagtggttta
     7801 gcttatcttt tgattattag tggcattatt gttttttcaa tgcctctctt ggctcttaat
     7861 tcgcctagtc taaataccaa gattaaagtg acggatcggc tcattgatat ccaattctgg
     7921 aaaatagctc ttactattat agttgacctc gttattctat atctttatag gagagagatt
     7981 cataatcttg cacttagcca tggttatacg ggttcaaatt ttcagtggtt ctttagaaat
     8041 gctaccagtt atgaaggtga gctaacagtg cgaacttcga ttcgggtcct cattcgtatc
     8101 attgacgtat ctgcttatat ttttggatat acttttatta ataatttctt catttatagt
     8161 cataaacgct ctaaagattt actgctctta gttccattct tgatttttat ttctaaaacc
     8221 ttattatctg ggggtagatt ggatattata aaaattttaa ttgcgtatgt tgtaatggcc
     8281 tatattcagc aaaaacgaaa agttggctgg gataaggtca tctcccataa atatatgaga
     8341 cttggttttg taggcttgat agctgggatt cctacctttt actattcttt attcttatct
     8401 ggacgttcta cgactagaac tgtatttgaa agtatttcaa cctatttagg aggttcgatt
     8461 cagcatttta atcagtatat tcaaaatcct attggagtag ctgaggtttt tggcgatgag
     8521 tcatttgtag ctattatgaa tattttgggt aatcttggct ttgtcaatta caatagtacc
     8581 gttcacttag aatttcggca gttagggatt actatgggta acgtttatac tttctttaga
     8641 agaccctggc atgactttgg gttagtcggt atgtatatct tttcctttgt tgtcggtgtg
     8701 ttttttgcta ttttttattt gaaattaaga aagagccgtg ctggttttaa attggatatt
     8761 catacaatta tttactctta tttcttttat tggatttttt tatcgtccat tgagcaatac
     8821 tcgtttacaa caatcagttt gtttacactt gtatttatag tcttggttta cctaatggct
     8881 ttcttctatt ggaatttgga tttccacaga ggaaaactag taattaaact ctctgacaca
     8941 agtattaaat cggaaaactg aaaacaataa aaatagagag gatagttgat gaatagcaaa
     9001 attaaaaata tactaactaa tttctcttat gtcatttctt caaatctttt gacagtcttg
     9061 acctcttcct tggttgtctt aattttcccc aaattaatgg gggtaacaga gtacagttac
     9121 tggcaacttt atatttttta tctgacctat atcggttttt tccacttggg ttggattgat
     9181 gggatttatc ttaaatatgg tggcttagaa tataataatt tagatagaaa acagttttat
     9241 tctcagatga ttctattttc tagcttctta atgattatct ccttgctatt gtttggttta
     9301 aatgtattag ctgtaacaga ttcgaatgca cgatatattt ataatatgac tattataagt
     9361 atgataatca caaatttaag aacgctctac gtgtatgttt tgcagatgac aaaccgcttg
     9421 aaggatagtt ccatcattct actcagtgat cgcgttttat atgtgctcct tttattcctg
     9481 tttattgtat ttggttggca tgaatacaag gttatgattt tggcagatat tctaggtcga
     9541 tcattttctc tcatactttc cttctggatt tgtaaagata ttgtgtttca gcctttgtca
     9601 aaattcatct ttaatataaa agagtctttt gataatatcc gagttggtat caatttaatg
     9661 ttatccaaca tcgcaagtag tttgattatc ggtattgttc gtctaggaat ccaatggaac
     9721 tggaatatcg aaacattcgg gaaagtatct ctgaccttga gtgtttccaa tctattgatg
     9781 actttcatta atgccattgg actagtcgtc tttccgctat taagacgaac aaaagcagaa
     9841 aacttaccta agatttattc taatttaaga aacgttttga tgcttatcat gttcgcgatt
     9901 ttgctcattt actatccttt aaaaattgta ttagacctct ggttgccagc ctatcaagat
     9961 gccttgattt tcatgaccct tattttccct atgtcagtct atgaagggaa aatggcattg
    10021 gtcattaata cttacttaaa ggcattaaga atggaaagag atatccttag agtcaatgcc
    10081 ttagtaatgt tgatcagtat gggagtgacc ctggttacaa catacctgtt aaatagtttg
    10141 gagctgactg ttgtatcgat agttgttttg ctagctttga gaagtatcat agccgaatta
    10201 attctgtcta aaaaactgga tgtttcggtt aagaaggata ttgtattaga atttcttttg
    10261 acgcttgtct ttatttcttc aagttggtat ttgccgattg ggctggcagt aattgtctac
    10321 acaatagcct acggtttata tctctatttg aaacacgaag atatcaaaac ctatttagct
    10381 tactttaaag ctagtaaaaa aacatcaaat taaaaaatta tataatgatt aagtggtaga
    10441 ttctatttct accgttttag atattcggga ggtaatgatg aaaaaaatta tgttagtatt
    10501 cggtacacgt ccggaagcca tcaaaatgtg tccattagtc aatgagttga aaaaacacga
    10561 agatatggaa acaattgtgt gtgttactgg acaacacaaa gagatggtta gtcctgtttt
    10621 agatttattt ggtgttgtac cagattatga tttagaaatt atgaaggcta accaaacctt
    10681 gttctctatc acaactagta tcttggaaaa gataaaacca gttttagaga aggaacaacc
    10741 agatattgtc ctagttcacg gtgacactac gacaacttat gcagcagcct tggcagcatt
    10801 ctatttggga attaaagtag gacatgttga agctggtttg cgaacgtaca atttacaaag
    10861 tccatttcct gaagaattta acaggcaatc gacatcaatc attgcaactt accattttgc
    10921 tccaactgag ttggctaaag aaaatctctt aaaagaaggt agagagaatg tttatgtgac
    10981 tggaaatact gtcattgatg ctcttacaac tactgttcaa gaggattata cacacactca
    11041 tttagattta aacgctaaca atcgtctcat cttattgact gctcatagac gcgaaaatct
    11101 cggcgaaccg atgagacata tgtttagagc agttaaacga gtattgaatg aatacgaaga
    11161 tgttaaagtc atttatccaa ttcataagaa tcctttggta cgtgaaacag ctgcagagat
    11221 ctttggagat acagaacgga ttcaaattat tgaacctttg gatgttcttg atttccacaa
    11281 cttcatgaac caaagttata tgattttaac agattctggc ggagttcagg aagaagcacc
    11341 ttctttagga aaacctgtat tggttatgcg cgatactact gaaagacctg aaggagtagc
    11401 ggcaggaacc ttgaaattag taggaactga cgaagaaaca atttatcaaa acttcaaact
    11461 acttctagat gattctggag aatacaaaaa aatgagtcag gctagcaatc catacggtaa
    11521 tggtgatgct agtcaacaga ttgttcagat tttgcgtggg atttaagaag attctctaaa
    11581 agagtctaag aggaatccac tccacaaaca taaaactctt atgctatcat ttatgattga
    11641 gatagactca taacttaata tttttatcct aagaaaattc gttcatattc aatatgaatg
    11701 aaaaacaacg aagaaaggtt atttcattat gaaaggtatt attcttgcag gcggctcagg
    11761 tacccgcctg tacccactta ctcgggctgc gtcaaaacag ctgatgccgg tttatgataa
    11821 acctatgatt tattatccgt tgtcgacatt aatgttggct ggaattaaag atattttgat
    11881 tatctcaact cctcaagatt tgccccgttt taaggacttg ctcttggatg gttccgaatt
    11941 tgggatcaag ctttcctatg cggaacaacc tagtcccgat ggacttgctc aggcttttct
    12001 tatcggtgaa gaatttatcg gtgacgatag cgttgccttg attttaggcg acaatatcta
    12061 ccatggtcct ggtctgagca caatgcttca aaaagcagcc aagaaagaga aaggtgcgac
    12121 tgtttttggc taccaagtga aggatccaga gcgttttggt gtggttgagt ttgatacaga
    12181 catgaatgct atttctatag aagaaaaacc ggagtatcct cgctccaact atgcagtgac
    12241 aggactgtat ttctatgata atgatgttgt ggagattgct aaacagatca aacctagtgc
    12301 tcgtggcgag ttagaaatta cagacgttaa caaggcttac ctaaatcgtg gtgacctttc
    12361 tgttgagctg atggggcgtg gttttgcctg gttggatacg ggaacccatg aaagcttgct
    12421 agaagcttct cagtatattg aaacggttca gcgtatgcag aacgttcaag tggcaaatct
    12481 agaagaaatt tcctatcgta tgggctacat tagtcgtgaa gacgtgctgg aattggctca
    12541 gcctcttaag aaaaatgaat acggacaata tttgctccgt ttgattggag aagcatagat
    12601 gtcagataat ttttttggaa agacacttgt ggtacgcaag attgatgcta taccaggact
    12661 gctagagttt gatattcccg ttcatggaga caatcgtggt tggtttaagg aaaatttcca
    12721 gaaggaaaag atgctaccgc ttggttttcc tgaaagcttc tttgctgcag ggaaactgca
    12781 aaataacgtc agcttttctc gcaaaaatgt tcttcgagga ctccatgctg aaccttggga
    12841 caagtatatc tctgttgcag acgatgggaa ggttttagga tcttgggtag atttgcgtga
    12901 aggcgagacc tttggaaatg tttaccagac agagattgat gctagcaagg gaatttttgt
    12961 ccctcgtggc gtagccaacg gttttcaagt cctctcagat acggtttcct atagctatct
    13021 ggtcaatgac tactgggctc ttgaactcaa acccaaatat gcctttgtta actatgctga
    13081 cccagcattg ggaattgagt gggaaaacct agcggaagct gaggtttcag aggcagacaa
    13141 acaccatcct ctattaaggg atgtcaaacc acttacgaaa gacgagttgt aaaaggaaac
    13201 attatgactg aatacaaaaa aattatcgtg acaggtggag ctggttttat cggttctaac
    13261 tttgttcact atgtttacaa taactttaca gatgtccatg tgacagtgct ggacaagctg
    13321 acttatgcag gtaatcgtgc caatattgaa gaaattttag gcgaccgtgt tgagttagtc
    13381 gttggagata ttgctgatgc agccttggta gataagttag cagctgaagc ggatgccatt
    13441 gtacactatg cggcagaaag ccacaatgac aattcgctta atgacccctc gccatttatc
    13501 cataccaact tcatcggaac ttatacactc ttggaagcgg ctcgtaaata cgaccttcgt
    13561 ttccaccatg tgtcgactga cgaagtctat ggggatctgc cgctgcgtga agatttacca
    13621 ggtcatgggg aaggaccagg tgagaaattt acggctgaaa ccaagtacaa tccaagctcg
    13681 ccttactcat cgactaaggc ggcttcagac ttgattgtca aagcttgggt gcgctcattt
    13741 ggtgttaaag caacgatttc taactgttca aacaactatg gtccttacca gcacatcgag
    13801 aagttcattc cgcgccagat tactaatatc ttgagcggta tcaagccaaa actctacgga
    13861 gaaggtaaga atgtgcgtga ctggattcat actaatgacc attcatcagg tgtttggacg
    13921 attctgacca agggtcaagt cggtgaaacc tacctgattg gtgcggatgg tgagaagaac
    13981 aataaggaag tgttggaact catcctcaaa gaaatgggac agccagctga tgcttatgac
    14041 cacgtaacag atcgagctgg tcacgacctc cgctatgcca tcgatgcaag caagctccgt
    14101 gatgaactag gatggaagcc agagtttacc aactttgaag caggtctcaa agcgactatc
    14161 aagtggtaca cagataacca agactggtgg aaagcagaaa aagaagctgt tgaagccaat
    14221 tatgctaaga ctcaggagat tattacagta taaaaagcag gaaatcgctg ctttttattg
    14281 ctatattggg aagagttaca tattagaaag gtctagagat gattttaatt acaggggcaa
    14341 atggccaatt aggaacggaa cttcgctatt tattggatga acgtaatgaa gaatacgtgg
    14401 cagtagatgt ggctgagatg gacattacca atgaagaaat ggttgagaaa gtttttgaag
    14461 aggtgaaacc aactttagtc taccactgtg cagcctatac tgctgttgat gcagcagagg
    14521 atgaaggaaa agagttggac ttcgccatca atgtgacggg gacagaaaat gtcgccaaag
    14581 catctgaaaa gcatggtgca actctagttt atatttctac ggactatgtc tttgacggta
    14641 agaaaccagt tggacaagag tgggaagttg atgaccgacc agatccacag acagaatatg
    14701 gacgcactaa gcgtatgggg gaagagttag ttgagaagca tgtttctaat ttctatatta
    14761 tccgtactgc ctgggtattt ggaaattatg gcaaaaactt cgtttttacc atgcaaaatc
    14821 ttgcgaaaac tcataagact ttaacagttg taaatgacca gtacggtcgt ccgacttgga
    14881 ctcgtacctt ggctgagttc atgacctacc tagctgaaaa tcgtaaggaa tttggttatt
    14941 atcatttgtc aaatgatgcg acagaagaca caacatggta tgattttgca gttgaaattt
    15001 tgaaagatac agatgtcgaa gtcaagccag tagattccag tcaatttcca gccaaagcta
    15061 aacgtccgct aaactcaacg atgagcctgg ccaaagccaa agctactgga tttgttattc
    15121 caacttggca agatgcattg caagaatttt acaaacaaga agtgagataa gtagtagaat
    15181 gattttctag tctaataaaa gaggcagata atgaactcaa aaggagctta aggtgtacga
    15241 ttatcttgtt gttggtgctg gtctctttgg tgcagtcttt gcccatgaag tagccttaaa
    15301 aggaaaaaag taaaagtcat tgaaaaacgg aatcatatcg tgggtaatat ctatactcgt
    15361 gaagaggaag gaattcaagt tcatcaatat ggtgctcata tcttccatac ttctgataag
    15421 gagagctggg attatgtaaa tcagtttgca gggtttaacc gttacaccaa ttctcctgtt
    15481 gcaaactata agggtgagat ttataacctt ccttttaata tgaatacttt caataaactc
    15541 tggggagttg taacgccagc agaagcacaa gctaagattg aggaacaacg tgctatttta
    15601 aatggtaaaa ctcctgaaaa tttggaagaa caggcgattt ctcttgtagg tacagacatc
    15661 tacgaaaaat taatcaaaga ctatacagag aaacagtggg gcaaaccaac tactgaactt
    15721 ccatccttta ttattcgccg tttaccagta cacctgacct atgataacaa ctattttaac
    15781 gatacctatc aagggattcc aattggtgga tacactcaaa tagttgaaaa atgttggatt
    15841 atgaaaatat tgatgtagaa acaaatgttg atttctttgt gaacaaagag caatatctga
    15901 aagattttcc taagattgtc tttactggta tgattgatga attctttgac tataagttgg
    15961 gcgaactaga gtaccgtagt cttcgttttg aaaatgagac cttggatatg gaaaattacc
    16021 aaggaaatgc agttgtgaac tatacggatg cagaaacccc atatactcgc attattgaac
    16081 acaaacattt tgagtttggg agtcaagcaa agactatcat tactaataga acattctaaa
    16141 acatgggaaa aaggtgatga gccttattat ccagttaata atgatcgtaa taatcatttg
    16201 tataaatcat ataaaaaact tgctgatgag caagggaatg ttatctttgg tggccgctta
    16261 ggacactatc gttattacga tatgcaccaa gtaattggag cagctttgca gtgcgtgaga
    16321 aatgagttag attcatactc aatgaaaatc aaagagcaaa ctaggaagct agccacaggt
    16381 tgctcaaaat actgttttga ggttgcagat ggaagctgac gcggtttgaa gagattttcg
    16441 aagagtataa acaagtaaaa ctgactacca gttattattt agaaatagta ttaaaaattg
    16501 gctctttgtc aactgtagtg ggttgaagtc agctaagctc gagaaaggac aaattttgtc
    16561 ctttcttttt tgatattcag agcgataaaa atccgttttt tgaagttttc aaagttccga
    16621 aaaccaaagg cattgcgctt gataagtttg atgagattat tggtcgcttc caatttggcg
    16681 tttgaatagg gtagttgaag ggcgttgacg attttctttt tgtcctttag aaaggtttta
    16741 aagacagtct gaaaaagagg atgaacctgc ttaagattgt cctcaatgag tccgaaaaat
    16801 ttctccggtt ccttattctg aaagtgaaac agcaagagtt gatagagctg atagtggtgt
    16861 ttcaagtctt ccgaataact cgaaagcttg tttaaaatct ctttattggt taagtgcata
    16921 cgaaaagtag gacgataaaa tcgcttatca ctcagtttac gactatcctg ttgtatgagc
    16981 ttccagtagc gcttgatagc cttgtattca tgagactttc gatgaaactg attcatgatt
    17041 tggacacgca cacgactcat agtacggcta agatgttgta caatgtgaaa gcgatccaac
    17101 acgattttag cattcgggag tgaaacagtc tgggagactg tttcagcctg agcctagaaa
    17161 tttgaaagcg aagctgttta gctaagtcat agtaaggact aaacatatcc atagtaataa
    17221 ttttgacgcg acatcggacg gctctatcat atttaagaaa gtgatctcgg atgacagctt
    17281 gtgttctacc ctcaagaaca gtgatgatat tgagattgtt aaaatcttgc gcaatgaagc
    17341 tcatctttcc ctttgtaaaa gcatactcat cccaagacat aatctcagga agacaagaaa
    17401 aatcatgttt aaagtgaa
//
LOCUS       DBEJZV010000042        15800 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.42, whole genome shotgun sequence.
ACCESSION   DBEJZV010000042 DBEJZV010000000
VERSION     DBEJZV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15800
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.42"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(2..997)
                     /locus_tag="ACL3S0_001816"
     CDS             complement(2..997)
                     /locus_tag="ACL3S0_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR1312685.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(994..1692)
                     /gene="liaF"
                     /locus_tag="ACL3S0_001817"
     CDS             complement(994..1692)
                     /gene="liaF"
                     /locus_tag="ACL3S0_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGR1312686.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(1769..2779)
                     /gene="fni"
                     /locus_tag="ACL3S0_001818"
     CDS             complement(1769..2779)
                     /gene="fni"
                     /locus_tag="ACL3S0_001818"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGR1312687.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(2763..3770)
                     /locus_tag="ACL3S0_001819"
     CDS             complement(2763..3770)
                     /locus_tag="ACL3S0_001819"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGR1312688.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(3757..4710)
                     /gene="mvaD"
                     /locus_tag="ACL3S0_001820"
     CDS             complement(3757..4710)
                     /gene="mvaD"
                     /locus_tag="ACL3S0_001820"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGR1312689.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(4692..5570)
                     /gene="mvk"
                     /locus_tag="ACL3S0_001821"
     CDS             complement(4692..5570)
                     /gene="mvk"
                     /locus_tag="ACL3S0_001821"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGR1312690.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELV
                     ERLEEKGAVQTWIESL"
     gene            complement(5692..6711)
                     /gene="cbpC"
                     /locus_tag="ACL3S0_001822"
     CDS             complement(5692..6711)
                     /gene="cbpC"
                     /locus_tag="ACL3S0_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HGR1312691.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIM
                     QTGWQYLGNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(6809..7498)
                     /locus_tag="ACL3S0_001823"
     CDS             complement(6809..7498)
                     /locus_tag="ACL3S0_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1312692.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTIQE"
     gene            complement(7510..8934)
                     /gene="gndA"
                     /locus_tag="ACL3S0_001824"
     CDS             complement(7510..8934)
                     /gene="gndA"
                     /locus_tag="ACL3S0_001824"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGR1312693.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(9010..10380)
                     /gene="mapZ"
                     /locus_tag="ACL3S0_001825"
     CDS             complement(9010..10380)
                     /gene="mapZ"
                     /locus_tag="ACL3S0_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGR1312694.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PFSEDILLPLPLDDEEQGLDPLLLEDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQASSNTTS
                     EPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLE
                     QILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGH
                     ADDLDY"
     gene            complement(10393..11550)
                     /locus_tag="ACL3S0_001826"
     CDS             complement(10393..11550)
                     /locus_tag="ACL3S0_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGR1312695.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARVVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(11635..12015)
                     /gene="rnpB"
                     /locus_tag="ACL3S0_001827"
     ncRNA           complement(11635..12015)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL3S0_001827"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(12036..12365)
                     /gene="gpsB"
                     /locus_tag="ACL3S0_001828"
     CDS             complement(12036..12365)
                     /gene="gpsB"
                     /locus_tag="ACL3S0_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGR1312696.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(12435..12962)
                     /locus_tag="ACL3S0_001829"
     CDS             complement(12435..12962)
                     /locus_tag="ACL3S0_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGR1312697.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            13028..13624
                     /gene="recU"
                     /locus_tag="ACL3S0_001830"
     CDS             13028..13624
                     /gene="recU"
                     /locus_tag="ACL3S0_001830"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGR1312698.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            13621..15780
                     /gene="pbp1a"
                     /locus_tag="ACL3S0_001831"
     CDS             13621..15780
                     /gene="pbp1a"
                     /locus_tag="ACL3S0_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGR1312699.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
BASE COUNT         4620 a         3755 c         2858 g         4567 t
ORIGIN      
        1 atcattcctt atctaacagg ggaatacgga tatcaactgc cagcccttgc ttgggagctg
       61 tcaagagttg aactgttcca gccatatctt caaccctctc cttgatattt cgcagtccat
      121 aactcaagtc gtctaagctt cctaaccgga aaccaatccc attgtccacc accttcagtt
      181 gcaattcaac atctgtctga tagaggtaga catctaggca agatgcctgg gcatggcgga
      241 gggtattgct aatcaactct tgcaggatac ggaagatatg ctcctcgatt ttcttaggca
      301 atttcgtcat attctgcttg agactaaccc taagatcact cttgtcctca agctctttta
      361 agagaatttg aatcccttct atcaagctct tctgctccag ttcaactggt cgcaaatgca
      421 agagcaaaac ccgcaaatcc ttctgggcag tttctaaaat agctgtgaca ctctgcaact
      481 ggatctgcat cttttctcta tccaatttca aagcctgctg actgataccc gataaaatca
      541 tgtgggccgc aaacaactcc tgactgactg tatcgtgcaa atcccgagca attcgcttcc
      601 gttctttctc gatgatttcc tcttcctgag caaggctatg attttcagct ttttgaagag
      661 cttctgtcaa aaggttaagt ttacctgata aggacttgaa actggcatcc aaatctggat
      721 ctgcaacctg aaccacttct tgccctgcca ataaacgctt gagattagcc tgcatttttc
      781 ttagagaaag ctcttcgatc cctcgccaaa acagggctaa gagacaggtt atggacatgc
      841 tgaaaaccaa caataaaaag acaaattttt ctgttttttc gacatcgtgc aaaaagatag
      901 accagtcaaa atcaagtatt tccagcaagc tgtgggagaa aaaaaagaca aacaggaagg
      961 aggtgagagc aataatgaca taggcttgtt ttttcatcct ctaaccacct ccacatcacc
     1021 aatcatagtg gtcaagaaaa tcttgacact cttgttactc ttgagatagt cttttgtttc
     1081 ttgatgatag tgttcattgc ggagggctcg cttgggctgg ttgaaaaaag tcaaatcccc
     1141 atagagacag ttaacgctga gactgacttc cacatctaca ggtacgatga ttttggtcgt
     1201 tcctaccatc tttctgagga taatgacatt gtcatgattg gttaagatga ccctctccag
     1261 atgaatagtg tccttgccca tgaagcgaaa gagattgata tcatcgaatt ggcaagtctg
     1321 gtagcttgaa aaatgatgaa gatttccaaa ccaacgattt ttctccttct taaccgtcac
     1381 gacctcttca aaaaccaaat tggtctgctc tttttcctgg ttcatcatcg ggtaaagaag
     1441 aaagaggcta tagataaccg caacaaaaat agctagaatc acaaaaggat tgagcataac
     1501 gatgaaaaag aagagaatgg ttgccgctac taaaagaaga ttatttccct ctttaccagt
     1561 gtagtagcga atcaaaagca aaaagaggaa tagtatcagc agaaaacgcg aaaaatgctc
     1621 tgataccatc aaaatcagag ctcctgtcag aagacaggct tcgataaata aaaagatttt
     1681 aaattttctc ataggttcat cctctccctt ctattttatc acaattcaaa aaagtcacct
     1741 cagtctgagg atggaaaaaa ggcgctggtt acgccttttt catctgatcc tttgcttctt
     1801 ttaattttcc ataaagaaga tagtctactt tttgtagatc tgctatggtg gcacagttaa
     1861 gggaacacat aatcaagcgt aggtctgctt tccagccttg gacaatgcca atcacttctt
     1921 caactgtgta ggtttcaacc aattccagaa cggttcgtga caatcccaca gacttagcac
     1981 caaaaaccaa gcacttaatc atatccagcg gattccgaac ccctccacta accaagagtt
     2041 cgaccttatc tttccattct tgggcattga gaagggcctg catggtagac tgaccccatt
     2101 gattgaggta atcacgctgg ccactacgac ggttttcgat ataggcaaag ctggtgccac
     2161 cacgacccga taggtccact gtacgaacac cgaattcata ggctctttcg attgtcttgg
     2221 catccattcc aaagcccact tccttgagga caataggaac gggaatttgc ttgctataat
     2281 ctgctagatg cgattgccag cttctaaact tcctttctcc ctcgggcatg agtaattcct
     2341 gcatgacatt gacatgcact tgcaatagaa caggattcat ctcttctaca gtctgaagtc
     2401 ctaactcgac aggtttgtcc aatccaatat tggttccaag gaggagattg ggatgactag
     2461 acttgacaga aaaagaatca tccgttggat ttttgagggc tgcgctataa gaacccgtta
     2521 caaataaaat accacaggat tccgccacct gagccagctt ttgattgatt tctcttccct
     2581 tattacttcc accagtcatg gcattgatat aaaaaggaaa gtcccacttt cgaccagcaa
     2641 actctgtcga aagatcgatt tcatccagat tgtaaagagg caaggaagaa tgaatcagct
     2701 ccacctcatc aaagctatta taggaacttt tctgctcaag ggcatagagg atatgctcgt
     2761 ccttacgatt tgtcgtcatg tcctatcctt tcttgatata agagctcaat ccccagatcg
     2821 gcccaacgat tttttaaggt ttcggttgat tgcgcatcaa aactcaaggc gatgccacag
     2881 tcaccaccac cagcaccact actcttggca acggcctgca aatcttgact ggcttctttc
     2941 aactgtctaa gcaaaggcgt gtaaatatct gtactcaagc cttctaaaag cttgctggct
     3001 acttctactt gctcgataac tttttcggct ttcccctgct ccaaggcttc gaccaaagaa
     3061 accaccgttt cttttgagga agttaaaaaa ttttgattga tattttgctt gatttgctgg
     3121 accatgtgac tcgatacagc cacttccttg gtccatccca ctaagaaatc acattctaaa
     3181 gttggtttca cttgtgagat aaaaaatccc caatcacgct ccagaactgt cgccaagttt
     3241 tcttcttcta accaagcagc caccttctgg cgatcaaatg actggtagag aaccaaatcc
     3301 tctgccacaa tacaggcaag gtcgcccatg gaaccattgt ctcctcgctt gagcaagaca
     3361 gcgctagtca gcttgaacaa gagattctga tcaaccgaaa gattatagag agccagtaaa
     3421 gccttgacaa ccaagacaac gacgctgcca ctagaaccta gaccaaactt tttcccttct
     3481 cgttccattt tgccacagat ttttagggaa aaaggtctta aattctgacc gcgaacagcg
     3541 aggaagtctc ccatcaaagc aatcgtttct tgaatcaagc tgtagtcagg attaggcctt
     3601 aagtccactg cgaaatcaaa catatctgaa tagatacggt agctgtcaga aaaagcaatt
     3661 tcagccctca tatagatggg aatatccttt atcaacgcta actgccctgg ctctaaaata
     3721 gcatattcac ctgcccaata gagttttccg caagttttaa cagcaatcat cttgactcaa
     3781 atcctttgtt tttgacacaa tcaagcgata acgctgaccg aaaatttctg ataaatgctc
     3841 caagtctttc tcctgacaga agaccttaac attgggacca gcatccatgg taaagtagca
     3901 ggcctctcct ttctcacgaa gctggcgaac aaagtccata gcctcataag aggcatccgt
     3961 cagataagaa aaggctggac tagcagtctt tgtcgtagca tgcatagcca gggcattttt
     4021 ctccgttaat tctccaatct tggcaaaatc attttccttg agataaatca gcatatcctg
     4081 atagtccttc tcagactgac gaacccagtc gtcgaaagtc gtcgaggttt ccacacaaag
     4141 tttcatcccg tcacggctag agattggttt tttcttgtcc tctagcacca acataatcat
     4201 agctagtttc aagtctgtct ctacagggta aatttctcca ctatccttat cccaggctcc
     4261 tagtggtcca taaaaactcc gagaagaaga gcctgaggca aacttggctt cctgcgctaa
     4321 ctgacttcta tccaatccaa gcttgaaata agcattacaa gccttgacca gggcggacaa
     4381 accactagaa cttgaggaca ggcccgctgc cgtaggcata ttgttttgag tatcgatacg
     4441 gacaaagccc tcaccagctg gacgataacg gtcaataatc ttactcatct tggcatgctc
     4501 gacctcattt tgtagctgac cattgatgta aaattcgtca gctgttacat tggctggtaa
     4561 aggcgacaag gtcgtctctg tatacatatt ttccaaagtt agagaaatac tgctagtagc
     4621 aggcaccatc tctttttctt ttttctttcc ccaatatttg ataatagcaa tatttgcgta
     4681 ggaacgtact gttacaggct ctctatccat gtctgaacag ctcctttctc ttctaatctt
     4741 tctactagtt cttgtgcgtg tgtcaaattg gttaccaagg ctatgataca acctcctagc
     4801 ccaccaccgc tcatcttggc acccagagca ccatggctaa gagtcgtttc aaccaaaaag
     4861 tctgcctcag ggctactgac tccaatttct tttaaatgta aatgcgcttg actgaggatt
     4921 tgtcccagtc cttcagcatc tttttgtgaa atcgcaactt ctgcttgctg ggttaattct
     4981 cccaaggcat gcaaaaacgg tagggcatcc ttgcccttat tttgaaccac ttggatggct
     5041 tcacgagtat gaccataaac acccgtatcg gcaatcacca aataggcgga taaatccatc
     5101 tcaagttctg taaatcctac gttcttgata aagcgaatag gttggtcact gagacaggtc
     5161 ttagcatcca aaccactagg attcatatgg gcaatcattt cagctcgatt gaccaagatt
     5221 tctagtacat catgaggcag atcagcctga tagtagtcaa ataccgcacg aatggccgct
     5281 atgctgatag ccgctgacga acccatcccc cgtttctcag ggatagccga gtcaatctca
     5341 caacgaatgc aggcttctgt gatatccaaa tactccagtg aggcataaac cgccatggac
     5401 aaggtatcct cctcataaag gcgccaagga ctctctgcag gaactacctt acaggtcacc
     5461 tccacctcca aaagaggcag ggaaatggca ggataaccgt aaacgaccgc atgttcccct
     5521 attaaaatta tcttactatg tgcctgaccg acaccaactt tttttgtcat tttttccttt
     5581 tactagacga aaaaacgtct tatttttcat acaagtatta attctttcct atctatttta
     5641 ttatattttc acaaaaaaag cgattgtttc cattcacaat cacttctttc attaccgaac
     5701 ccattcacca ttataattga cagaatagcc atctacagtc gtattcactg ccaaggcacc
     5761 tgagctataa gcatagtacc agttgccatt gacctggaac caacctgtct tcatgtctcc
     5821 attacctgca tttaggtagt accaagttga accatcttga taccaaccag ttgccatagc
     5881 tcctgatgaa cggagatagt accatttgtt cccaaggttt tgccaacctg ttttcatatc
     5941 gccatttggg tggtctaaat aataccaagt ggtaccttcc tgataccagc cagtggccat
     6001 tgctcctgag gaacggaggt agtaccactt attacctaga tattgccaac ctgtttgcat
     6061 aataccagtt gttggatcta ggtagtacca tggagcaggt ttgcttctat caatgtcaat
     6121 agtaacatga aaatcttgag tccaaccctt agcaacttca ccaattggta gtggattgta
     6181 agaatcatcg ccaaaatttc ctagcttatt taaataatac caatgaccct cttcataaat
     6241 ccagcctgtc tttacagcat aattattatc aaaataataa gttctctttt cagcagatag
     6301 aggatattgt tcaccgtata cttttcctgt attttcagac gtttttgcct ctagtacttg
     6361 tttatctgtt tgttctagca aagcaccatc ttgtccaaaa tagtaccact tctcctgaag
     6421 gccaatttca ttaactggtt ggttatcgaa taaattatca cgataacctg ttccaggaat
     6481 ttctaagtat tgccaaccga caaccatctc tccaatatca ccaaaatagt aagttttacc
     6541 gtctatttta tgccaataga ttgctttatg atcatctttt acataatatt ttctattatc
     6601 cttatcaaca aatcggccac ctgtggtatt cgcaaatacc gtatttgtag ctagcaaacc
     6661 aaagaaaaag actgctagta gaacttgcat catttttttc aaaagtttca tctatatatc
     6721 ctcctaaaac gattgtagca aagacccgac tgcatgtcaa tatataaaaa ctcctcaaaa
     6781 aagcagttac acaactgcaa ctgcttatct attcttgaat ggtatatcca acaccacgca
     6841 cggttttaat gtagcttttt tggcctttaa catcaagctt gctccgtaga tagcggatat
     6901 agacatctac gatatttgtc tcggtcgcac tttcatactt ccaaacactt tccaacaatt
     6961 gctcacgagt caatactttc ttgcttccca taagtgtcgc caaaaggtca tactcacggc
     7021 gggtcagagc aatcatctct tcaccacgat aaaccgtgtg atgttcaaca tctatcctaa
     7081 gattgcggta ggtccttgga actttcatca gactgcagtg ttgatcaatg aagtcccgac
     7141 ctcggaagat cgccgaaata cgcgctacca gattttcgat aaggactggc ttatagatgt
     7201 atgaaactgc aaaacgctga acaacttcca gctcttcttg caagtcttcc caatgatcta
     7261 aaatcatgat gactgaggca ggtttagttc ggctcaattt ttctgcaaaa tcctgagcca
     7321 tcatatctcc cagattaacg ttcaataaaa tcaaatcata gtctgtctga agagccatgg
     7381 agagggcttt ttgcccctcc tctaccagat caacccgata ctgctctttc tggagttcca
     7441 aacttaaaaa atgagctaga tttcgttctt tctcaagtaa taaaatccgt ttccccatgg
     7501 ctgacctact tatttttcgt cataccaaga gtagtggaag gttccttctt tgtctttacg
     7561 ttggtaagtg tgggcaccaa agtagtcacg ttgtgcttgg atcaagttag ctggaaggtc
     7621 agctgaacgg tagctatcaa agtaagtaat agctgctgag aaagttggca ctggcacacc
     7681 agcttgaacc gcaagagcta cgatatcacg cactgcttgt tgatacttag cagtaacatc
     7741 caagaagtat tcatccaaaa gaaggttggc aaggtctgca tcacggttgt aagcatctgt
     7801 aatcttttgc aagaaacgag aacggatgat acagccatca cgccagatag atgcgatatc
     7861 tgcaaatggc aagttccagt tgttttcttt agaggctaca cgcaattgag caaatccttg
     7921 tgcgtatgaa atgatttttg agaagtaaag ggcttgacgg attttttcaa tcaattcagc
     7981 cttgtctcct tcaaagttga aggcggctgg ttttggaagc accttgctag catgtacacg
     8041 ttcttctttg taagttgaaa tgtagcgtgc aaacactgac tcagtaatca gtgacaatgg
     8101 tacaccaagg tcaagagatg attggctagt ccatttacca gttcccttgt tacctgcagc
     8161 atcaaggatg tagtctacga ttggtccatc ttggccttca tcgtctttac ggctcaagat
     8221 atcagctgtg atttcaatca agtagctgtc taattcaccc ttgttccact cagtaaagat
     8281 ttcagccata tcttctgcag aaaggcctag caagtgttgc atcaagtcat agctttctgc
     8341 gatcaattgc atatcaccgt actcaatacc attgtgaacc attttcacat agtgaccagc
     8401 tccatcagga ccgatgtaag tcacacatgg tttgccatct tctggtgctt tagctgagat
     8461 ttcttcaaga acatccgcaa ccaattcgta ggcttctttt tgtccaccag gcatgataga
     8521 aggaccttca agggcacctt tttcaccacc agaaacccca gtaccgataa agttgatacc
     8581 agagtttgcc aattcttcat tacgacggat ggtatctttg tagaaagtat ttcctccgtc
     8641 aatcaagata tcacccttgt caaggtgtgg aagaagggct tggatagtag catctgtacc
     8701 aggtccagct tgaaccatca gcatgatacg acgaggtttt tcgattgagt ttacaaaact
     8761 ttcaacgtca tagcttggta caaagttctt ttcaggatgg caagcaatca catcttccgt
     8821 tttttcttta ctacggttgt agatagcaac tgtgtaacca cgagattcaa tattaagggc
     8881 aaggttacga cccattacgg ccatacctac gacaccaaag ttagcttttg tcatttgaca
     8941 ctcctcttgt ttcatttgtt ttattttatc atttttactt ttgaaaagaa agaattttgt
     9001 aacgactgct tagtagtcca agtcatccgc atgaccagcg ccatttccga caaagtagcc
     9061 tgtcttacag ttaagggtaa agagataggt tccatctggc ttatagaggt tgtaataacc
     9121 attgccgtta acgatattga cacgttcaag gatatattgg tctccagtga tatagccacg
     9181 tgaacgtgaa gtcgctagaa tttgttccaa gacaccatcc gcaaaatccc aggcagagtt
     9241 attactatca tcaatagcag actgattata ggcaacacga ctggcacttc tttgaacagc
     9301 aacccctgca ctcgagagac ccatattgac ttcactgcga ctacttctag tctcatttga
     9361 actacttggt tttggctcac tagtcgtatt tgaacttgct tgacttgaac ttgagctaga
     9421 agtacttgtt tgctggctct taccaagact gatagcctta tctagcactt tatcaagctc
     9481 cgtatttcca gttttaatat ccgtaaattt agcatccgat ttggctttgg cattggtatc
     9541 caacacacca tccacaatag ctggtttctc aaattgagca ttgacatctt gaatagcctt
     9601 gatttgcgtt gctagactat catatttaga tttggcaagc gtatgttcac gactaccttc
     9661 cagcttatca agtaaagtct tgagttgact cagtttatca aactggctat ttttcaaagc
     9721 cgttttattg ctatctgtgt aaaaggcgtc ataaagtgta ttaaaatcat ccacatccga
     9781 ttgattggct gtagttgatt gagaagtttc aatttcctta gtcgaacgag ccacttgacg
     9841 gtagacataa taagcactga cacaaataat tactgataca agcgccaaaa cggtcaaaat
     9901 aaagcctttt ttacttttct tttctgagtc ctcttgatcc agacgagaaa ggttttgctc
     9961 ctcttccact tcttcagtca tttctgttgg attttcatcc tctagcaata gaggatccaa
    10021 gccttgctcc tcatcgtcca gaggcaaggg tagtaagatg tcttcagaaa atggaacttc
    10081 ctccgaagaa gcttctgact tctctacagc ctcacgcatc tcttgaatta aatcatccag
    10141 actctgagtt tcaacgaact cctctttttt gtattgacga gtcgcaaact tatccgcctc
    10201 aatttcatct ctgtgttgct taacatactt gtccaaaatg gaatcctcag gcaagactcc
    10261 tgcttccact tcttcatttt tacgaatagc ttgaccaact gttagctctt ttgcttcatc
    10321 aaaatcaaat tgcggttctt gaccttcttt tttatgacga tttcgtcttt ttttactcat
    10381 gagtatccct ttctatttta cctcttgccg tttgacacgc tgaccaaaat attgatatag
    10441 atccactttc aaggttccgt tgtataactt acgcttctta tctgcttggc taccatactt
    10501 gctttcaaaa gcttcatcac tagtcaggat aaatttgctc caagttttca gcggtgcaaa
    10561 tacttgcccc atctcagcat agagcttagt cacccctgca tcatctgaca aacgttcacc
    10621 ataaggcgga ttggaaatga ttactccatt gattttatcg gaacgtaaat cctgcacgcg
    10681 catctgctta aaagtaatgt ctcctgcaac accagctacc tgagcattgg ccttagcaat
    10741 ttccaccacg cgagcatcaa tatcacagcc catgatatcc agctcaagct cacggtctac
    10801 ttttttagcc gcttctgtgc gcacttcttg aatcaagcga tcgctgatcc agttccattc
    10861 ctcaaatgca aaagagcgac gaagacctgg cgccatcttt ctagcaatca taactgcctc
    10921 aatacagaaa gtccccgaac cacaggtcgg atcaatcaaa ggcttgtctg gataccagtt
    10981 agaaagttgt aaaatggctg ctgccatatt ttccttgata ggagcgccac ctttttcggt
    11041 acgataacca cgtttaaaga ggctagaccc ggtcgtatca atcatgacag ttgccacatc
    11101 tttgagaata gagacctcaa tcttaaactc tgggccattc tccatcagag gaaccccttc
    11161 tgggcgagca tagtgtttct gcaatttctt gacaacagct ttcttagaaa tagcctgaac
    11221 actgggctca ttgtgaagtt tggacttaac acatttagct tttgaaatcg ggaaccgagc
    11281 tccaagtggt aaataatttt cccaatccaa agcgaaaact ccctgaaata gctcttcaaa
    11341 agtcttagct gggaacgttc ctacgataat tttgatacga tctgctgccc gaagccaaag
    11401 gttggtttcg ataatagctc tcacgtctcc ttgaaaacga acacgtccat tttcaacctg
    11461 acaatcgtag cccaactctc gcacttcacg accaacgaca gcctcaagcc ctgctgccac
    11521 agttgcaatt aaattaaatt cttttttcat gttacagtct tgcaagacct ttctatatgt
    11581 ccactttaaa aaatgaggtt gagaaaattt ctcagcccca acctatatgc aattttctat
    11641 aagccatgtt ttgttccaga agtgactagg accacttcct tcgataatca tctgtctacc
    11701 actaacagct ctagctgata gcagtcagaa tactacgttc gtttccgcgt actccatgcc
    11761 ccgaccaaaa tttgggttgc tagcttgagg ggtttaccgc gttccactct ctctgtttcc
    11821 agaaagactc cgtcactgtg gcactttcaa gcctactctg gcctatccaa ggacttagcc
    11881 atttcaactg ccgtaacgat ttctcgtccc taggcttatg gtttcgccta gcacaaacac
    11941 tacaggcatc acagcctgtg ctagcatgga ctttcctcat gagaagcaat tctcctcacg
    12001 cgattatcca aaaattgcac atctcaaata actacttaaa aatctgagtt atctaaaatt
    12061 tgtttaccaa aaacttcttt ttccaatcta ttcaggcgtt tcaaaatatc aaaattcgtc
    12121 atagaacttg taattgccgc ttcaaggggt tctgcttgaa ctggtgaagg tttcggttta
    12181 cgagttaatt cttccttcaa atccgcaatt tcctgacgaa gtgacttgac caaggcagca
    12241 taggtttcat agtccttgat gacatcgtct aaaaactcgt caacttctac tttattatag
    12301 ccacggactt cacgtccaaa ctcttgttca aaaatatctt tcgctgaaaa aataatactt
    12361 gccatgtctc tctccattct cgcttgctag tattattata taaaaaaagg caaacaaaaa
    12421 tcaaggtcaa agcttcaatt ttcggaaaaa ttttcagcaa gttcatttaa ttgatcaaat
    12481 gttaatctct ttataaaata gtcctcttga tttttcatct tttggtaaaa ataagctagt
    12541 tttgtttcat tttcttcatc ataaaaaaga taggaactag tcgtgttttc cagcaaaaac
    12601 tgctggtaat ctcttaactg ccccttgtgt tcatagcgag gataggcata tttgacaaag
    12661 tctacctgct taaagcgact cagtttcatc tgattgcctt cattccaatt ttccccatgg
    12721 gtttcaaaag caaaaatggt ggccaactgg aaaccgtatt cagttttcat ctcctgagca
    12781 acctctaaaa cccaatattc aaaacccaaa ctccctgtaa acacaagcca agacacccca
    12841 tctgctgcca tagcctctaa atctttacgt atcgcttttt taatcaattt aagacgagga
    12901 tccttatcag aaaataaacc caaatcaaaa gcagaatagc ctaaaaccaa agctgtagcc
    12961 atttttaacc ctttctgtgc aaattatggt ataataaagt gatgttattg taccaataag
    13021 gagaattatg gtcaactatc cacataaagt ttcatcacaa aaaagacaaa catctctttc
    13081 tcaacccaaa aatttcgcaa atcgaggaat gtcttttgaa aagatgatca atgctaccaa
    13141 cgactactat ttgtctcagg gcttggctgt tatacataag aaaccaactc ctattcaaat
    13201 cgtacaagtg gactatccac aacgaagtcg tgccaagatt gttgaagcct attttcgaca
    13261 agcttcaacg acggactatt ctggcgttta taatggatat tacatcgact ttgaagtcaa
    13321 ggaaacaaaa caaaaacgtg cgattccgat gaaaaatttt catccacatc agattcagca
    13381 tatggaacaa gtccttgccc aacaaggaat ctgctttgtc cttcttcact tttcttctca
    13441 gcaagaaacc tacttattgc cggcattcga tttgattcgc ttctatcatc aagataaggg
    13501 acaaaaatca atgccacttg aatatattcg agaatatgga tatgaaatca aggctggtgc
    13561 cttccctcaa attccttatc tcaatgttat caaagaacat ttattaggtg gtaaaacaag
    13621 atgaacaaac caacgattct gcgcctaatc aagtatctga gcattagctt cttaagcttg
    13681 gttatcgcag ccattgtctt aggcggagga gtttttttct actacgttag caaggctcct
    13741 agcctatccg agagtaaact agttgcaaca acttctagta aaatctacga caataaaaat
    13801 caactcattg ctgacttggg ttctgaacgc cgcgtcaatg cccaagctaa tgatattccc
    13861 acagatttgg ttaaggcaat cgtttctatc gaagaccatc gcttcttcga ccacaggggg
    13921 attgatacca tccgtatcct gggagctttc ttgcgcaatc tgcaaagcaa ttccctccaa
    13981 ggtggatcaa ctctcaccca acagttgatt aagttgactt acttttcaac ttcgacttcc
    14041 gaccagacta tttctcgtaa ggctcaggaa gcttggttag cgattcagtt agaacaaaaa
    14101 gcaaccaagc aagaaatctt gacctactat ataaataagg tctacatgtc taatgggaac
    14161 tatggaatgc agacagcagc tcaaaactac tatggtaaag acctcaataa tttaagttta
    14221 cctcagttag ccttgctggc tggaatgcct caggcaccaa accaatatga cccctattca
    14281 catccagaag cagcccaaga ccgccgaaac ttggtcttat ctgaaatgaa aaatcaaggc
    14341 tacatctctg ctgaacagta tgagaaagca gtcaatacac caattactga tggactacaa
    14401 agtctcaaat cagcaagtaa ttaccctgct tacatggata attacctcaa ggaagtcatc
    14461 aatcaagttg aagaagaaac aggctataac ctgctcacaa ctgggatgga tgtctacaca
    14521 aatgtagacc aagaagctca aaaacatctg tgggatattt acaatacaga cgaatacgtt
    14581 gcctatccag acgatgaatt gcaagtcgct tctaccattg ttgatgtttc taacggtaaa
    14641 gtcattgccc agctaggagc acgccatcag tcaagtaatg tttccttcgg aattaaccaa
    14701 gcagtagaaa caaaccgcga ctggggatca actatgaaac cgatcacaga ctatgctcct
    14761 gccttggagt acggtatcta cgattcaact gctactatcg ttcacgatga gccctataac
    14821 taccctggga caaatacccc tgtttataac tgggataggg gctactttgg caacatcacc
    14881 ttgcaatacg ccctgcaaca atcgcgaaac gtcccagccg tggaaactct aaacaaggtc
    14941 ggactcaacc gcgccaagac tttcctaaat ggtctcggaa tcgactaccc aagtattcac
    15001 tactcaaatg ccatttcaag taacacaacc gaatcagaca aaaaatatgg agcaagtagt
    15061 gaaaagatgg ctgctgctta cgctgccttt gcaaatggtg gaacttacta taaaccaatg
    15121 tatatccata aagtcgtctt tagtgatggg agtgaaaaag agttctctaa tgtcggaact
    15181 cgtgccatga aggaaacgac agcctatatg atgaccgaca tgatgaaaac agtcttgagt
    15241 tatggaactg gacgaaatgc ctatcttgct tggctccctc aggctggtaa aacaggaacc
    15301 tctaactata cagacgagga aattgaaaac cacatcaaga cctctcaatt tgtagcacct
    15361 gatgaactat ttgctggcta tacgcgtaaa tattcaatgg ctgtatggac aggctattct
    15421 aaccgtctga caccacttgt aggcaatggc cttacggtcg ctgccaaagt ttaccgctct
    15481 atgatgacct acctgtctga aggaagcaat ccagaggatt ggaatatacc agaggggctc
    15541 tacagaaatg gagaattcgt atttaaaaat ggtgctcgtt ctacgtggag ctcacctgct
    15601 ccacaacaac ccccatcaac tgaaagttca agctcatcat cagatagttc aacttcacag
    15661 tctagctcaa ccactccaag cacaaataat agtacgacta ccaatcctaa caataatacg
    15721 caacaatcaa atacaacccc tgatcaacaa aatcagaatc ctcaaccagc acaaccataa
    15781 catttatcat ccagattttt
//
LOCUS       DBEJZV010000043        15021 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.43, whole genome shotgun sequence.
ACCESSION   DBEJZV010000043 DBEJZV010000000
VERSION     DBEJZV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15021
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.43"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(67..615)
                     /locus_tag="ACL3S0_001832"
     CDS             complement(67..615)
                     /locus_tag="ACL3S0_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGR1312700.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(630..1478)
                     /locus_tag="ACL3S0_001833"
     CDS             complement(630..1478)
                     /locus_tag="ACL3S0_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGR1312701.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            1666..3015
                     /gene="trkA"
                     /locus_tag="ACL3S0_001834"
     CDS             1666..3015
                     /gene="trkA"
                     /locus_tag="ACL3S0_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGR1312702.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            3019..4458
                     /locus_tag="ACL3S0_001835"
     CDS             3019..4458
                     /locus_tag="ACL3S0_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR1312703.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(4585..6264)
                     /locus_tag="ACL3S0_001836"
     CDS             complement(4585..6264)
                     /locus_tag="ACL3S0_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR1312704.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFLFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEYVASSNDIILEEETSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKSLQFVLEHYQAV"
     gene            complement(6334..7746)
                     /gene="lacG"
                     /locus_tag="ACL3S0_001837"
     CDS             complement(6334..7746)
                     /gene="lacG"
                     /locus_tag="ACL3S0_001837"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR1312705.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(7756..8100)
                     /locus_tag="ACL3S0_001838"
     CDS             complement(7756..8100)
                     /locus_tag="ACL3S0_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR1312706.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(8268..10154)
                     /locus_tag="ACL3S0_001839"
     CDS             complement(8268..10154)
                     /locus_tag="ACL3S0_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HGR1312707.1"
                     /translation="MVIRVFDKQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRRDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEISGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(10156..11478)
                     /locus_tag="ACL3S0_001840"
     CDS             complement(10156..11478)
                     /locus_tag="ACL3S0_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR1312708.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMVVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            11646..12869
                     /locus_tag="ACL3S0_001841"
     CDS             11646..12869
                     /locus_tag="ACL3S0_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR1312709.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            14468..14752
                     /locus_tag="ACL3S0_001842"
     CDS             14468..14752
                     /locus_tag="ACL3S0_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312710.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            14745..14894
                     /locus_tag="ACL3S0_001843"
     CDS             14745..14894
                     /locus_tag="ACL3S0_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312711.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFMAL"
BASE COUNT         4925 a         3133 c         2387 g         4576 t
ORIGIN      
        1 ttcaaaacac tgttttgagc aacctgcggc taacttccta gtttgctctt tgattttcat
       61 tgagtattag tcctttttca aacttcctgc acgagtttgg gttcctgcat aggcaagtaa
      121 gagaagagtt cctgcaatag ctacagatac accattggca attcccgcaa caatcccttg
      181 tgcaaatact ttttctgccg cttcttgata aatcacaaca tctccaagtg gtgccaagac
      241 accccaaaca agggcatttg caagtagttg aatgaggtta aaaataagaa tatctttcca
      301 gtcaaaaaca ccattgatca cgcgaacgta ctttctaaaa agtcccacaa ctaaaccaaa
      361 gagtccgcta gcgataatcc aagtccacca tagaccataa ccagcaagag agtccttgat
      421 tgcatgacca atcaacccga caagcaaacc gataatcggt ccaaaaataa tagaaagtag
      481 cgcttgtacc gcatactgaa gctggatgct tgtatttgga acaggggttg gaatgttgat
      541 catcccgatg acgacaaaga gggcagcgcc aattccgaca gcaacaactt gtttaattgt
      601 aaatttaatt tccatactat tctcctattt tatccttcta ttttctttat ttcaatggtc
      661 caagatgaac cgacacctac attataggcc ttggcaaagg aaccttggtt gatagccaaa
      721 cctaaacgat agagagagtt gatgtaaagg atgggttgcc caattctcac atctgcaaat
      781 gatttgccat agacaacctg attttgatag accagcatat cagcatgata gatggtcact
      841 tcaaaacgat caccaaattc tggttccagc ttgtaaaatt cttcccgtgt gatagaggtc
      901 caaagcgaac cgaaacgcac atccagaata tcaatggctc ccttcaccag atgatcttct
      961 atgatggtcg ctacgactgg aagctctaca atctgttcca cactgagctc tggccctact
     1021 tcctcaaaag taatgtgacc actggccagt ttagcaccag tataggcata gacatcacga
     1081 ccgtggaagg tataagaatg ctctgtgttt tgacgcctat tggccacctc agaaatctca
     1141 cgaatggcta caatgccaac gtgtttcttg ataaaggaaa gcgtcccatt atctggcgtg
     1201 acaatgtatt gattttttgc agtcttggca actacactct tacgtttcga accgacacct
     1261 ggatcgacaa ccgatacaaa cgtcgttccc tcaggccagt aatccaccgt ctgaaagaga
     1321 cgatagctcc cctcaaaaat attataaggc gtgatatcgt gcgtcaagtg atggattttt
     1381 aaggttggag actcttctaa agccactcca atcatagccg ataccgcacc atcaaccaga
     1441 ccaaagtctg attgtaatac cagtaaatta ttattcattt tatctccttg tatatccttt
     1501 atcataccat atttcagaga aagtcgctaa tagctatttc aattggttag ggtatagttt
     1561 taccttatag cgaattttca ctaaaagctc ttgttattag ctagtaggtg cattttttct
     1621 tgaaaaaggg tatgatagtt acatcatgaa aaagtaggtt ttattatgaa aattatcctt
     1681 gtcggagggg gaaaagttgg ttttgccctc tgtcgctcct tggttgcaga aaagcatgat
     1741 gttttgctga ttgagcaaga cgaagctgtt ctcaatcata ttgtcagtcg ctttgatatc
     1801 attggtatcc ttggtaacgg ggccgatttt gccattcttg agcaagccag cgtccaagat
     1861 tgtgatatct ttatcgccct gactgagcac gatgaagtca acatgattgc agcagttcta
     1921 gccaagaaaa tgggagctaa agaaactatc gttcgggtgc ggaaccctga atattctaac
     1981 tcttatttca aggaaaagaa tattctcggt ttttctctta tcgttaatcc tgagctcttg
     2041 gctgcccgcg ctatcgcgaa tatcattgac ttccccaacg ccctgtctgt cgaacgcttt
     2101 gctggtggac gcgttagcct catggaattt gtcgtcaagt ccaccagcgg tctttgccaa
     2161 atgcccattt ctgattttcg taaaaaattt ggtaatgtca ttgtctgtgc gatagagagg
     2221 gatcatcaaa ttatcattcc aagcggtgac atgactgtac aggataaaga tagaatcttt
     2281 gtcactggta accgtgtcga tatgatactc ttccataatt attttaaatc acgcgccgtg
     2341 aagagccttc tcatcgttgg agcaggtaga attgcctatt atctacttgg tattctcaaa
     2401 gatagtcgta tcgatacaaa agtcattgaa atcaatcctg aaatcgccag cttctttagc
     2461 gagaaattcc caaatctcta catcgttcaa ggagatggaa ccgcaaaaga tatcctgctg
     2521 gaagaaagtg ctcaacacta tgatgccgtt gcgactctaa caggagtcga tgaggaaaat
     2581 ctgattacat ctatgttcct tgacagggta ggtgtacaga aaaatattac taaggtcaat
     2641 cgtaccagtc tcctcgagat tatcaatgcg cctgattttt caagtatcat cacacctaaa
     2701 agcatcgctg tagatacgat tatgcacttt attcgtggtc gagttaatgc ccagtattca
     2761 gaccttcaag ccatgcacca tctagccaat ggccaaatcg aaaccctgca attccatatc
     2821 aaggaagcca ataaaatgac tgccaaacct ctttctcaac tgaaattgaa aaaaggggtt
     2881 cttattgcag ccattattcg aaagggcaag actattttcc caactgggga ggatatgttg
     2941 gaagttggag acaagctcct agtaacaacc ttgttgccaa acatcaccaa gatttatgac
     3001 ttgattgcga ggtaagaaat gaataaaagt atgattcgtt acctcctttc aaagttactt
     3061 ttgattgaag ctgttctcct cttggttcct gtggctatcg ctgtctatta ccgtgaatcg
     3121 agccaagtct ttacagccct cttttcgacc atagggattc tcgtattgtt aggcggttca
     3181 gggagtttac agaagccaaa aaatcaacgg atttatgcca aggagggagt cttgatcgtt
     3241 gccctctgtt ggatcctttg gtctttcttt ggtggtctcc cctttgtctt ttctgggcaa
     3301 atccccagcc ttattgatgc cttttttgag attagttccg gctttacgac tactggagca
     3361 agtattttga acgacgtttc agttctcagt cgttccctcc tcttctggcg aagttttacc
     3421 cacttgattg gagggatggg agtgcttgtt tttgcacttg ctattatgga caatgccaaa
     3481 aatagccacc tagaggtgat gaaggctgag gttccaggtc ctgtttttgg caaggttgta
     3541 tccaaactaa aaaacactgc ccagattctc tatctccttt atctagctct cttctccctc
     3601 tttgtcatca tctattatct agctggtatg cctctctacg atagttttgt cattgctatg
     3661 gggacagcgg gaactggagg ctttaccgtc tataacgacg gaattgccca ctatggcagc
     3721 tcactgatta cctatctggt cagtatcgga gttctggttt ttggagtaaa tttcaacctc
     3781 tactactacc tcatgctccg tcgcatcaag gccttctttg gagatgaaga gcttagggct
     3841 tacttggtca ttgtactggt ttctacaggc ttgattagcc tcaacaccct ctacctctac
     3901 ccagggtttt caaagagctt tgaaatgacc ttcttccagg tttccaacat cattacaaca
     3961 actggttttg gatatggaga tattaccaac tggcccctct tctcccagtt tatcctcctt
     4021 ttcctcatgg caatcggtgg ctctgctgga tcaactgcag gtggactcaa gattattcga
     4081 ggcctcatcc tttcaaaaat tgccaaaaac caaattttgt caatcctatc gccccaccgt
     4141 gttttgaccc tccatgttaa taaaacggtg attgacaaag atacccagca taagattctc
     4201 aagtactttg tcatctatgc tatgattttg ctagcgctta tctttattgt cagcctagat
     4261 agcaatgatt ttctggtcgt gaccagcgct gtctttagct gtttcaataa tatcgggcct
     4321 attctaggaa ccacttctag tttctcaatc tttagtccca tctcaaaaat tctcctatcc
     4381 tttgcaatga ttgcagggcg cttggagatt tacccaatcc tccttctctt tatgaagaga
     4441 acttggtcta agagataaaa tacaaaatcc ctctttttac aattgtaaaa agagggattc
     4501 ttatattaaa aaagggggaa cgtttttaaa tccaagcctg tctgtaagca aagtccttac
     4561 tcaaataaaa gatggaaaaa cttactacac agcttggtaa tgctccaata caaattgtaa
     4621 ggatttactt ggattctttg ttaaatgaat atattccatt cctctggtag caactatctg
     4681 aatacctaat ctttctgcat ccaccttcat ctctctataa taactccgaa cttgtggggc
     4741 cagaataatt aaatcataaa cacccataat atcataatga gctccgtacg ctcctgaatt
     4801 cgcaatcact ctaacttctg ctaattgagc gccctcgtta attgcattgg ctaattgcgc
     4861 acttgttcca gaccctgcac aaagaaccag tactttcaac tccttacttt ttattacatc
     4921 tatctcacca ggcattattt cacttgtctc ctcctctaaa ataatatcat ttgagcttgc
     4981 aacatattct ttcatcagta actgtctatc atacgctcta cagaatggca aataaatcaa
     5041 tatgtcaaca actaaaatca aagataaaaa tacaaaggag atagattgaa aattcgttcc
     5101 aattaacaat cccaagggac caggaaaggc ccaaggtaac tggatataaa atccattcat
     5161 tccaaagaaa tcaataaaga cctttcctag aaatacattc actggtggag tcatcaaaaa
     5221 aggtacaaaa agatagggat tcaaaataac tggcatacca aatagaagag gttcattcac
     5281 cgcaaataaa acaggagtaa ttgtagcttt acctaccgat tttaattgtt tagaccgcat
     5341 aaagaaaatc aaaataaatg gtacaacaaa ggtagccccc gttcctccga tagcagcgat
     5401 ataatttccg aaattaggcg ttaaagaatg ataaggaaac tgcccatttg caagaagttg
     5461 agcattctct tccatattgc tcagttgtaa agctgtaaca gcaggtaaga caatagatgg
     5521 tccatgaatt ccaacaaacc aaagcaaagc gcacataaac caaatcaaca tcatagcagg
     5581 atatgattct gcccccttaa aaataggagt caatagttgt tgaaatactt gggcaaaagg
     5641 aacatctaaa ctaaaccgag atacaatatc taacaaacca ctaataagta aaacaaaaga
     5701 aaaaagaaaa atatctctaa aagcttgtga tatagcccca ggaacttcct taggtaaatg
     5761 aatagtaatg tctcgcttaa tacagaatcg gtaaacattt acagtaataa aggcactgac
     5821 aaacgaagtt atcaatcctt gagatcctaa atagtttgtc gacaaacttg tagatcccgt
     5881 tttctcatca actacaagcg ttacagttaa tacaagatag ccacatatgg ccgccaacat
     5941 tgcagaagta tcatttatta cctttccagg aggcattttt ctattaacat ttccagccaa
     6001 tgactttgca actgtccctg aaacaataac acccaaaact cccatggtta gcatatacac
     6061 tttcctcatc caggcaatag ctggactcgg taactctact ccgaaatttt taggaatcat
     6121 aataataatc atcaaaaagc ttgaaaacat aattaaaggc atagtagcaa taaatccatc
     6181 tttaatagcc atcatataat tattagtaga aattttttca aatttccctt gttgcttttc
     6241 aatggcagcg actaacttat ccataaaaac tcctcctgta aaaaatttaa gctcatagtt
     6301 aaaatatatt aaacatcagt caaatcgcta accttaattc cgttttaatc cttttaccca
     6361 aagagcactt ttcttaatat atctcttctg tgtttcataa tcaacaaaga aaagaccata
     6421 tcgcttattg tagccattcg cccaagaaaa ttgatcttgc aaagaccata taaaatagcc
     6481 ttgaatattg actcccctat ctcgagcctc taaaactttg tgtaaatgtt gctcaatata
     6541 acggattctt ttactgtcat caataatatc attctcgccc tctggcttaa cctctttaag
     6601 ggctgtacca ttttcagtta aataaatgac cggatgttga ggatattctt ctttgatacg
     6661 aagcaacata tcaaataacc cttgaggata aatattccaa tcccaatctg ttgtcggaat
     6721 accaggcttt tttacaaatt cacctagagc atttaattta aaagaagact gtccttttat
     6781 tcctgttgaa ttaaattctt gtctattttc acctttgtat tcacgaataa attctgaacg
     6841 ataataattc atcccaaaca tcgtattaag aggtgcagct cttttcataa tttctaaatc
     6901 accatcttca ataataaagc tagaattatt agcttccaat atttgattca agtgaaaaag
     6961 cgtgtcatca ctgtagtagc ccaaaaaagt tccatctaat agaaatttat tattataaac
     7021 atcataccgt ttagctgcta aaatattttc tttttgccca tcaataggat agcctggctt
     7081 taaagcatga atacaaccta tctctccctc aattcctaat tgatgaaatt cgaggactgc
     7141 aagagcatgc gccaacaaca tattatgatt cgcttgaatt gcttcagata attgaaaatg
     7201 atgatttgga ggaaactgac ctcctatata ttgacctgca gcaagagaca tcagttcatt
     7261 gattgtaaac caatgcttga cttctgtaaa ttcttggaaa caaaagcgag catatcgtat
     7321 gaaacgatca atattctctc tattcaacca atcccctgtt tctaacattt tctgaggcga
     7381 atcaaaatga tgtaaagaaa caaacggaat cacattatgt tttaagcaag actgaaagac
     7441 tctatggtaa taacgaacag ctaatatatt aggctcccca tctatatcag gaaatatacg
     7501 aacccaagaa atagataaac gcaaagcctg caaaccatgt tctgccgcca aagctatatc
     7561 ctcttcgtaa cgataataaa aatcactagc tggatctggt aagaacggac tgttttcttg
     7621 caaataaaca tcccacatat ttgttccttt gccatctacc ctagttgcac cctctacttg
     7681 ataagcagcg gtagcagctc ctaataaaaa ctccttcggt aaggctttaa cctgtaaatt
     7741 ttccatgact aatcctcatt gcaaaccaat atgttcttca atctttcgaa ttcgttcata
     7801 ttcatcaata aaaaacttga cctgatcata caatagcatc gttgtcatca aagtatcttg
     7861 accatgaatc ataataaagc tcacttcaaa attatctcca tatgcctcct ctgctaataa
     7921 attagtctgt tctcgatggg cagacactat tgagtcgttt gcagactcaa ccaattctct
     7981 tgcctgttca aaatatccat ctctcgcaaa cgccaaagca tccatcaaat ctgaccttgc
     8041 atctcctgcg taagcgacaa ttgtaaaacc aagcatattt atttcttctt ttgatttcat
     8101 ctttcttcct cctcaatctt gatccatctt ttacacatca ttattaaaat gacttcgcta
     8161 cgatacaaat agaaagtcga ccctaaatat cttaaaaatc cttaaatttc ataatattta
     8221 gggtcaatct tctctgaata ccttagttca ttttctatac ttatgattta taagtggaaa
     8281 ccagcgtaat tttttgctac ttcaattaca cgataaacat ccaaattaga ttgaaatagc
     8341 aattcgtgcc cacggatata attcaacaca tttctccatt catcttgagc ttgccttgtt
     8401 tttccagttg cttgaagata taaagccttc gccatcttaa caacatattc acgatgataa
     8461 ctgagctgtt tccattcatc cttttgacta tttaataact tagaaatatt ttcctcaata
     8521 attggtaaaa aattatcagc tagattgtaa gctatataat aatgattcgc taaaacatca
     8581 ctttgacggc tgccaattgc attaaaataa tcacaagagg aataaatgga taatttttct
     8641 aaatattcaa caacagactg ccaattttcc ccatacaaag cagaaaagta ttcttcaatc
     8701 aattcttcat aacttcttgt cttcttccag agcatttccc ccataacata attaggaaaa
     8761 ttatgaggga atccggcacg taattcttga cacgaaatgt aaccgttcaa atgtaggtta
     8821 gaaagataag atacatctct gtaaatggtt tgactaattt tcatatagcc taaatcgcca
     8881 taatgagcac gccctaaagg atagtcatat acgaaactat ctcctttaaa tgttttttgc
     8941 cactcaaaaa gataagataa attttcctca agagaattcg gaagtataat tttattacgc
     9001 agataaggtt taggcgtagg tatggaattg tcaaaatcta catctgcata actcatttca
     9061 aatgttcttg taatcggtgc aaacatcatg gtaaagcgtt caggattatc taatttttct
     9121 ttctgaggcg cccatagcaa ctcatggtaa agcagaaaac aaatctttgt atctaatccc
     9181 tcactcgtta aagccctatc caattgattg agaatacgaa tatactgatc cgaaaccaat
     9241 tcttgtctac agttttcgca ttcacaaata ttattacgag catccgacaa ccatacatgt
     9301 aagtagttaa catcaggtct tttcttggca taatccttga taatttctac catcttatcc
     9361 gccacatctg gatttgaaaa atccagactg gttaaaatcg gagccgtatt aaataattct
     9421 cgtttcccgc ttatttcagc gacatagggt ttcttctcct ctgaaatact aagacctgat
     9481 tcccagccaa attttgaaga gtaacctaaa acttcacctg tccatccatg accaacacga
     9541 tgatgaataa gacctctttt ttgcaattct ttatccaacc tatcactcaa ttcttgtact
     9601 aattcatttg aaaattgttc tttatttaga tatggattaa attcatgttc ataccaacgt
     9661 ttcaaaaaag agtagggatt ttcaaactgg atgaaaaaac tgttcatccc aatcttaggt
     9721 agccaatcaa tgaaatctag tatattttca aatgaatccg ctccctctat acatactccc
     9781 ctatgatagt aactggctgt ttcatctata gatagctgtt tatctaaaaa atcttcaaat
     9841 cgtaactctg gaacaaagtc atgtccgcgc cctggtctag tatacacaac cccaaattca
     9901 tgaaacattc ggtaaattcc aataagtaaa cctacaattg tattagactc aattctcccc
     9961 ttacccttgt ctaatgagat aagaacatgg tctcttctat cctctttatt gactaatcct
    10021 acaaaaatat ccgcttcctt ctcctcgaca agttctatgt cagtcttaaa gacccgattt
    10081 atatagtaac ttaattcctc taaggcaaag ctagaataag tatttttctg cttatcaaat
    10141 actctgataa ccatcttatt tccctccaac agtagctttt tctttttcaa gattgcgttt
    10201 atctgcaatt ttgaagaatg gataataaat tgctacagaa accaaaatca aaacaacttg
    10261 taatagagct cctcgccaac tagctcctgt cgcaaggaag cctcctatga tcggtggcat
    10321 tgtccacgga aggattacac ctgttgtata gggtactaat cctacaacca ttgatacata
    10381 ggtaattaag gcattgattg taggagtagc aataaacgga atcagcataa tcggatttaa
    10441 aactgttgga aacgtaaata gaatagctgt attgatatta aaaatagacg gtataatagc
    10501 tagcttacct aatgttttat tcgcacgact cttactaaat aggaagagac aaatcgcaag
    10561 accaatagtc gctccaccgc caccaataaa tacaaataaa tctttaaacg gtaatgtaat
    10621 aatgtgttgg agtgtttgtc ctgcagccac agcttcttgg ttttctgtag taaattgtaa
    10681 ccaaactgga tctacaaaag catttaaaac ttgtccccca ttaactccac agaaccaaaa
    10741 gaatgagttt acaataacac atagaatcat acctggaagc gttcctgcaa ttaacttaag
    10801 cggtgttcca acaattgcac ctaggagtcc gttgagacct cctgcaactc ctgccgcttc
    10861 aagacctttt aagaccagag cccacaaaac aaaagtagta aagccaggta aaagagctga
    10921 aaatgattta cttaccacat ctgggacacc acttggcatt tttatcgtaa ttccgcgctg
    10981 gataaacata cgataaatct ctgctgtaac caatccaata gtaatcgcca taaacaaaga
    11041 agatgcattc aggctagaaa atggtattgc gccgccaaat aactgcttga cctgctcccc
    11101 atttttatca taaaccatac tcgaaaaacg aggtgccatc aatacaaaac tggataaggc
    11161 tatgatccct gccgacggac catctgtacc atatccttcc gacaacctgt aggcaatacc
    11221 gaaacaagcg accaaggaga taatcgctac tgttgactga ttcatagttg tcaagatact
    11281 tagcaatcca acactattca gccaatttgt aaaatcctct tgaggccaac tgattagaat
    11341 aagaaataaa gagccgacta aaatcaaagg cattgccatc ataaatcctt cacgaatagc
    11401 tttcaaatgc cgttggttgc caactttttc accaaacgga gcgacttttg tttctaaaaa
    11461 cgctaaaata ttgttcatca ccggaactcc tttttttatt ttttataaat taaatatacc
    11521 actaacagaa agcgttgtca atatattttt tgttgttttt acaatatttt tttctttgta
    11581 tagaataata attttaattg attttttctt atgtttaata taaaataaac caaaggagga
    11641 aacaaatgat tacaaaacaa tcagcctttt tacaaaatag agccactata ctggagtttc
    11701 tatatcgaaa tccagcaaca tcccgtacag atattgttaa tgaaacaggc cttactccag
    11761 caacaacgac taacatcata aaagagctaa gcgaacagtc cctcatatac gaaactggtg
    11821 atgaatttag cgagttttcc ggatctggaa gacgtagaaa aactatttct atcacagata
    11881 atattccgta tgttgttgga ggtattgaaa taaacgtcct aggtatcttt ctcagtctat
    11941 gtgacttaca agggaaaact cttttcgaga cagaaatttt gaatgaagat tatcctattt
    12001 cagaaatcaa ttccaccatt accaatatga taaaaacagc tatagagtac gtccctttgg
    12061 aaacaaaatt acttggattt ggcttatcaa tacctggaca ttataacaaa gactccggaa
    12121 gtatcattac aaacaacccc atatgggaat cttttaattt attaaatgta attaaaagat
    12181 tcaattttcc ttttattgta aaaaataata tcgattgtat ggctatagga caataccttt
    12241 ttaatccaca caataccccc gataacttta ttttcctaca cgctggatta ggtatttaca
    12301 cttccttttt cacaaaagaa aaaataggag cctctaaaaa tccttatatc ggagaaattg
    12361 gacacaccat tgtcgaattg aatgggcaat attgtgaatg cggaaaaaaa ggttgtttac
    12421 aaacatatat ttcggatgct tggttaatca aacacgccca attattattt aaaaattccc
    12481 aactaactgt actaaaaagc cttgtaaaga ctgaaaaaga cattcattta gacacccttt
    12541 taacggctta taatttaggc gactccgctt tacgccaaca aattgataaa ggagtcaatt
    12601 tattggccac ttctattgca aatcttctcc tcatcaatcc tgctgataaa atctatatca
    12661 acagtcaatt gcttaattat caacctttca ctcatgaagt cagggataaa atccaagacc
    12721 agctccactt cgttcccttt actcgtaata tagaaattga aattttacct tacaacaaac
    12781 atcgtggaag tataggagct tgtgcattag ctatcgttgc ttttttcata gagcatagca
    12841 atgtattaca agatattatt tcaccttaat atatattaga aatctataca cctgtttaaa
    12901 tcaactataa cctgtagtag atatctcgta tttagacaat atgaaaacaa gacgacttcc
    12961 atataggaaa ccgccttctc gctatgttga gtgatttata ttaaaataac ttttcttcta
    13021 gctgcatttt attattataa aaacattcat cataaccccc agaacttaaa taacaatttt
    13081 tattcaagat acatactcct agaataaact ttatatgaaa tccccatttt tgtttttaca
    13141 attctccgta tactcaatga aaatcaaaga gcaaactagg aagctagctg caggctgctc
    13201 aaaacactgt tttgagcttg tagatagaac tgacgaagtc agtaacatct atacggtaag
    13261 gcgacgctga cgtggtttga agagattttc gaaaagtatt agttaaatct tgtttaatat
    13321 ctctacacca tactatttta catatattat ttagcgccac atagtactga actctctcca
    13381 aaaacggtta tgcctctttg aatagggcgt tatcacaaga aaagcatctc cacgtttcaa
    13441 cttcatatgg ctcaaaaaca atcaattgat gctaaaacct gtacctagat gtttcggttc
    13501 ataaaaccat gaaactgtaa aagtggatga aattgatagc gatagtcaaa tcaagaggca
    13561 tcataactct aaaaagtcac aatatataag ttcatcctcg gaaaaatatc attctaattg
    13621 ttgaaatgcc tacatgaaaa gaaacgtcaa atgctcatga aacaacgaat acaggtatca
    13681 aaactatgac aaaacaagtc cctaaattta ctaaagacac tgctcaactt tacacctgta
    13741 aatggttgtt gtataataaa gttacaaaga tgtacgacca cactgttgta aatcatagtg
    13801 ttcgcgaata tattactgat agcatttcta caaatacaat tgaaaaggct ggataggctt
    13861 taaacgaaat atgtcagtgt tttggcattc ctagccttca tatcatttaa agaattgtat
    13921 agacaaaatt tttcccaata cagacactcg taacaactgc ttcatttttc taccaacata
    13981 tttaggaaca ggataagata caagaggatt aatccataga tcagttctat accaatctaa
    14041 gacaaataag ctaaaaaaac gattgataat aagcaaatag attccaaatt ttctctatct
    14101 gctcatttta ataaacaata ctagtgtaac tatccttcca gtcagaagct tgtcaaatca
    14161 caccgaaaat tcttctaaaa tttatctcgt taggcaatca agcaaaaact cgacgatagt
    14221 acaaacatta tcatacagaa ttgacttcct aaattatata ctttagtaat gttttcggat
    14281 aagaaaaaag attcatttta catttctaaa cattcttttc taagatgaaa aacagaattt
    14341 ttcgattgtg atttaaagca acaagaagat tttcagtatc atcctataga tacgagctaa
    14401 ttaagaaaaa ctacattttc gaatataaac tacaataata taaactaaat tttataggag
    14461 gaagacaatg gattggtacg attatatgat acaggcatcc aaacaatcac aattcaacgc
    14521 aagccattgg tttcgctatt tgcgaaaagt tatttttgaa gactattctt atttaacaaa
    14581 ccaagatgta gaaaagttgc tagactccaa agaactaacc cgttttcaaa aaattagctt
    14641 gaagtatgcc tttcaagagc atactccaac tcataaatat gtgatttcat taaataaacc
    14701 tgctaagtta accaatgttc aaaaattgat ggagaaatac aaacatggat aaaatgaaac
    14761 cggtcttcca agccctaaat aaggaattaa ttcaggaaaa tctgacttta acaattatct
    14821 gtgtcgatgg ttatgtctta gaatatcatg gtttacgtgc cacacaagat gttgatgctt
    14881 ttatggctct ataatatttg tagtgggtaa atcccctatg gatattatgg agcctatttt
    14941 tgtgtagaaa aaaagtccca tatgacctat aatgaaaagc gacaaaacaa ctcattagaa
    15001 agaatcatat ggaacaatta c
//
LOCUS       DBEJZV010000044        14963 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.44, whole genome shotgun sequence.
ACCESSION   DBEJZV010000044 DBEJZV010000000
VERSION     DBEJZV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.44"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            97..1050
                     /gene="coiA"
                     /locus_tag="ACL3S0_001844"
     CDS             97..1050
                     /gene="coiA"
                     /locus_tag="ACL3S0_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGR1312712.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESSEHIANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWHPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            1069..2871
                     /gene="pepF"
                     /locus_tag="ACL3S0_001845"
     CDS             1069..2871
                     /gene="pepF"
                     /locus_tag="ACL3S0_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR1312713.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENRGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTIFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            2873..3586
                     /locus_tag="ACL3S0_001846"
     CDS             2873..3586
                     /locus_tag="ACL3S0_001846"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGR1312714.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFIMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            3653..4594
                     /gene="prsA"
                     /locus_tag="ACL3S0_001847"
     CDS             3653..4594
                     /gene="prsA"
                     /locus_tag="ACL3S0_001847"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGR1312715.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(4713..5054)
                     /locus_tag="ACL3S0_001848"
                     /pseudo
     CDS             complement(4713..5054)
                     /locus_tag="ACL3S0_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5466..5561
                     /locus_tag="ACL3S0_001849"
                     /pseudo
     CDS             5466..5561
                     /locus_tag="ACL3S0_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(5814..6434)
                     /locus_tag="ACL3S0_001850"
     CDS             complement(5814..6434)
                     /locus_tag="ACL3S0_001850"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR1312716.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LHTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(6434..6916)
                     /locus_tag="ACL3S0_001851"
     CDS             complement(6434..6916)
                     /locus_tag="ACL3S0_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGR1312717.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(6916..7758)
                     /locus_tag="ACL3S0_001852"
     CDS             complement(6916..7758)
                     /locus_tag="ACL3S0_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGR1312718.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(7853..8641)
                     /locus_tag="ACL3S0_001853"
     CDS             complement(7853..8641)
                     /locus_tag="ACL3S0_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGR1312719.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQALK
                     HLDKPIIDLSGWQHPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDKAYKS
                     HITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTMSNMN
                     EGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLESSPKT
                     DLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            8795..10174
                     /gene="glmU"
                     /locus_tag="ACL3S0_001854"
     CDS             8795..10174
                     /gene="glmU"
                     /locus_tag="ACL3S0_001854"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGR1312720.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            10184..10729
                     /locus_tag="ACL3S0_001855"
     CDS             10184..10729
                     /locus_tag="ACL3S0_001855"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR1312721.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDENETLEVLEVSLEEAKELIQ
                     SGRICDAKTIMAVQYWELQKK"
     gene            10741..11055
                     /gene="macP"
                     /locus_tag="ACL3S0_001856"
     CDS             10741..11055
                     /gene="macP"
                     /locus_tag="ACL3S0_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGR1312722.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            11072..11764
                     /locus_tag="ACL3S0_001857"
     CDS             11072..11764
                     /locus_tag="ACL3S0_001857"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGR1312723.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVFGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            11841..12332
                     /gene="rocS"
                     /locus_tag="ACL3S0_001858"
     CDS             11841..12332
                     /gene="rocS"
                     /locus_tag="ACL3S0_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGR1312724.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            12430..13020
                     /locus_tag="ACL3S0_001859"
     CDS             12430..13020
                     /locus_tag="ACL3S0_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGR1312725.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            13029..14792
                     /locus_tag="ACL3S0_001860"
     CDS             13029..14792
                     /locus_tag="ACL3S0_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGR1312726.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         4719 a         2670 c         3122 g         4452 t
ORIGIN      
        1 agcttagctt tttttcaacc cactacagtt gacaaagagc cgaattttcc tgatcttttt
       61 tcttttttac gaatgatata gaaaaggagg gaattcatgt ttgttgcgag agatgctagg
      121 ggagaattgg taaatgtgtt agaggataaa cttgagaagc aagcatacac ctgcccagct
      181 tgtggaggcc agatccattt gcgtcaagga ccaagtgtac ggacgcattt tgcccataaa
      241 tccttaaaag actgtgattt tttctttgaa aatgaaagtt cagaacacat agccaataag
      301 gaatccctct atcactggtt gaaaaaagag acaaaggttc aattagagta cccgctttca
      361 gaacttaaac agattgcgga tgtatttgta aatggcaatc tagctctaga agttcagtgt
      421 agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg gctatcgtag tcagggttac
      481 caagtactgt ggttgctggg tcaaaaactg tggctcaagg agcgtttgac tcgtctacag
      541 caaggttttc tttatttcag tcaaaacatg ggcttttatg tttgggaatt agacaaggaa
      601 aaacaagttt taagactcaa atacctgatt taccaggatc tccgcggtaa actccattat
      661 caaatcaagg aattttccta tggtcaaggt agtttattgg aaatattgcg tcttccctat
      721 aagagacaaa aaatatctca ttttacagtt tctgaggaca aggacatctg tcgctatatc
      781 cggcaacaac tttattatca aaatctcttt tggatgaaag aacaagcaga agcctatcaa
      841 aagggagaaa atatcctgac ttatggactg aaagaatggc atccacaaat tcgaccaata
      901 gtgggcaaat ttttccagat tgaacaagac ttgactagct attatcagca cttttatacc
      961 tattaccaaa aaaatcctca aaatgattgg caaaagcttt atccaccagc cttttatcag
     1021 caatatttct tgaaaaatat ggtagaatag aaaggatgga ggaatctaat ggtattacaa
     1081 agaaatgaaa taaatgaaaa agatacatgg gatctatcaa cgatctaccc aactgaccag
     1141 gcttgggaag aagccttaaa agatttaaca gaacaattgg agacagtagc ccagtatgaa
     1201 ggccatctct tggatagtgc ggataaccta ctagaaatca ctgaattttc tcttgaaatg
     1261 gaacgccaga tagagaagct ttacgtttat gctcatatga agaatgacca ggatacacgt
     1321 gaagctaagt atcaagagta ctatgccaag gccatgacac tctacagcca gttagaccaa
     1381 gccttttcat tctatgagcc tgaatttatg gagattagcg aaaagcagta tgctgacttt
     1441 ttagaagctc aaccaaagct gcaggtttat caacactatt ttgacaagct cttgcaaggc
     1501 aaggatcacg ttctttcaca acgtgaagaa gaattattgg ctggagctgg agaaatcttt
     1561 ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg atattgtgtt cccttatgtc
     1621 ctagacgatg atggtaaaga agttcagcta tctcatggga cttacacacg tttgatggag
     1681 tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc tttatgcgac ttacgaacaa
     1741 ttccaacaca cctatgccaa aaccttgcaa accaatgtta aggtgcaaaa ttaccgtgct
     1801 aaagttcgta actacaagag tgctcgtcat gcagccctcg cagcgaattt tgttccagaa
     1861 agtgtttatg acaatttggt agcagcagtt cgcaagcatt tgccactctt acatcgctat
     1921 cttgagcttc gttcaaaaat cttggggatt tcagatctca agatgtacga tgtctacaca
     1981 ccgctttcat ctgttgaata cagttttacc taccaagaag ccttgaaaaa agcagaagat
     2041 gctttggcag tcttgggtga ggattacttg agccgtgtta aacgtgcctt cagcgagcgt
     2101 tggattgatg tttacgaaaa tcgaggcaag cgttcaggtg cctactctgg tggttcttac
     2161 gataccaatg cctttatgct tctcaactgg caggacaatc tggacaatct ctttactctt
     2221 gttcatgaaa caggtcacag tatgcattca agctatactc gtgaaactca gccttatgtt
     2281 tacggagatt actctatctt tttggctgag attgcctcaa ctaccaatga aaatatcttg
     2341 acggagaaat tattggaaga agtggaagac gacgcaacac gctttgctat tctcaataac
     2401 ttcctagatg gtttccgtgg aacaattttc cgccaaactc aatttgctga gtttgaacac
     2461 gccattcacc aagcagatca aaatggggag gtcttgacaa gcgatttcct aaataaactc
     2521 tacgcagact tgaaccaaga gtattatggt ttgagtaagg aagacaatcc tgaaatccaa
     2581 tacgagtggg ctcgcattcc acacttctac tataactact atgtatatca atattcaact
     2641 ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc atggtagtca agaagaccgt
     2701 gaccgctata tcgactacct caaggcaggt aagtcggact atccacttaa tgtcatgaga
     2761 aaagctggtg ttgatatgga gaaggaagac tacctcaacg atgcctttgc agtctttgaa
     2821 cgccgtttaa atgagtttga agcccttgtt gaaaaattag gattggcata aaatggttga
     2881 atcgtatagt aagaatgcta accataacat gcgtcgtcct gtcgtcaaag aagaaattgt
     2941 agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc ttgaaagaat tggaagactt
     3001 tgcccgcaag gaaaatattc ctattattcc ccatgaaacg gttgcttatt tccgttttat
     3061 tatggaaacc atgcagccta aaaatattct ggaaattggg acggctatcg gtttttcagc
     3121 tctcttgatg gctgaacatg cgccaaatgc taagattaca actattgatc gtaatccaga
     3181 aatgattggt tttgccaagg aaaattttgc ccagtttgac agtcgcaagc aaatcactct
     3241 cctagaggga gatgcggtgg atgtcttatc tacactgaca gagtcttatg atttcgtatt
     3301 tatggattct gccaagtcta aatacatcgt ctttctgcca gaaatcctca aacatttgga
     3361 agttggtggt gtggttgtct tggatgatat ttttcaaggt ggtgatgttg ccaaggatat
     3421 tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc cttcaaaaat tatttgatgc
     3481 aaccttagac aatccagaac tcaccgcaac attagtgcct ttaggagatg gtattctcat
     3541 gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc gaatgatttt cagaaaaatt
     3601 taagaaaaaa tagtaaaata gatagagtaa cacttatctc aaaggagtag acatgaagaa
     3661 aaaattattg gcaggtgcca tcacactatt atcagtagca actttagcag cttgttcgaa
     3721 agggtcagaa ggagcagacc ttatcagcat gaaaggggat gtcatcacag aacatcaatt
     3781 ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc ttgttaaata tgaccatcca
     3841 aaaagttttt gaaaaacaat atggctcaga gcttgatgat aaagaggttg atgatactat
     3901 tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt gtcttgtcac aagcaggtat
     3961 gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa ttagttgagt tggcagttaa
     4021 gaaggtagca gaagctgaat tgacagatga agcctataag aaagcctttg atgagtacac
     4081 tccagatgta acggctcaaa tcatccgtct taataatgaa gataaggcca aagaagttct
     4141 cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta gccaaagata attcaactga
     4201 tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat tctgcttcaa cagaagtacc
     4261 tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat ggtgtttctg atgtgattac
     4321 agcaactggc acacaagcct acagtagcca atattacatt gtaaaactca ctaagaaaac
     4381 agaaaaatca tctaatattg atgactacaa agaaaaatta aaaactgtta tcttgactca
     4441 aaaacaaaat gattcaacat ttgttcaaag cattatcgga aaagaattgc aagcagccaa
     4501 tatcaaggtt aaggaccaag ccttccaaaa tatctttacc caatatatcg gtggtggaga
     4561 ttcaagctca agcagtagta catcaaacga atagtccaaa tcaatgagtc agggaaaaaa
     4621 ctcgacttca ggaaaaaatg aagcaaacat tcccacaata aaacgcatag tacaaggttt
     4681 gtactgcccc ccaaaaaagt tagacaatta atttatccga aggatttagt tctgtattgc
     4741 acagagctaa gtccttttag ttttatctta attctcttat tgttgtaata atcaatatag
     4801 tctataatgg cttgttccaa ttgattaagt gatttaaatg tttgctcata gccataaaac
     4861 atttcggatt ttaaaatgcc aaagaaagat tccatcctac cgttgtcttg gctgtttcct
     4921 ttgcgtgaca tagatgcttg aattccctta ctctctagga agcgatgata agaatcgtgt
     4981 tggtattgcc agccttggtc actatggaga atcgtattct cgtagtgctt ctctttgaat
     5041 gcctgttcca acattaacga tcaatcaatt taatcatata cctaagatta gaattgttta
     5101 tcccaaattt atttgaaagc ttctctaagc tatatccttg ttttctaagt tcatagatct
     5161 gaactttatc atcataattc aatttcataa taaaaacacc ccaaaagtta gattttttct
     5221 gtctaacttt tggggtgtag ttcatgtaca cctgatatga tgcgttttat aattttaaag
     5281 actttttgac cagcctcatt ttttaacttg atactcagtg aaaagcaaag attaaactag
     5341 gaagctagct gtaggctgct caaagaacag ctttgaggtt gcagataaaa cttgtgaggt
     5401 aaccaacata tataatgtga agctgacgtg gtttgaatag attttaggag ggtatgagtc
     5461 tggaagtttt aatggataat gcaagattcc atagaatggg taagctagag ttcttatgtg
     5521 aagagtttgg gcataaactt ttaccttttc ctccctactc atcttagtat agaaaagtga
     5581 atctgaaata gtacataact gcttctaaaa cattcttata aattgattta aattctcaaa
     5641 tcatattatt cagttcttat ttcattttgc tctacaatcc tgttgagaag acacgtgttc
     5701 atatcaaaaa ggtattggca agttgcaata cctttttaca aggttctttt gtcttatttt
     5761 tgtttcaact gactatatct cctatggttc tagttcagaa ggctaggcta taattatgat
     5821 tgataagaag tatcattcca agtattgaga gtgaatgttt caaaatcatg ggtttctata
     5881 atggtcaggc tggcatttgc tagaccgcca tctttacgaa gaagtggttc tttatagcct
     5941 aggagagtat gaagactggc agtaagattg gcgccgtgtc cgacaattag aatacgctca
     6001 gctggactat cttttaatga tttgataaat tggatggtcc gctgagttgt actatagagg
     6061 gattcggctc cgaacattcg agtgtcaaat tgagcaagat ttgaacgaaa agcctggatt
     6121 tgttgcgggt aaatagcttc cagggttgca attttcaaac cttctaactt cccaagttgc
     6181 cattcacgga gattaggaac gatttctaaa gaacaggggg tatggagttg actttggata
     6241 atctcagcag atttgaccgc tcgaggtaaa tcacttgaat aaatctgatc aaaaggaatt
     6301 tccttgagat actggccaag tcgttttagg gtttcaatgg attcaggaag aagaggagaa
     6361 tcaccactag caccttgaaa acgaccttct tggttccaga gggtacgacc gtggcggaca
     6421 aagtagagtt tcattacttg atgtcctcca aaatatctac aaagtctgcc tttacaaagc
     6481 tagccaagtc ttgtggcgcg acgataatgc tgtgtccgac ttcgcctgca gagacaatca
     6541 tttgatccaa atctagagca attttatcga taaaaatggg ataattgtgt ttctgacgaa
     6601 ttccgacagg attattggct ccatgaatgt aaccagttgt tttttctaag tccttttgtg
     6661 gaatcatgct cactttttta ttgccagaaa ttttagctag tttcttttca gacaagtgct
     6721 gagtgatagg gacaattccg ataatcggtc cggtcttgtc tcccaaaagc gccaaggttt
     6781 tgaaaatctg atctcgttca taaccttgag gaagctctcc ttctagggca ttgatttgaa
     6841 tcccctgatg agggatagct gctttagata ggatttgttc caccaatgtt tttttgattt
     6901 taactttttt tgccattatt tatatttatc ctccaattga ctcatccaaa taccaagcca
     6961 gattcccagc gcaaagaaga aggcgatgat gacataaccg acaagtgaaa gtcctgtgta
     7021 ttggatactt tcagcgtttc ctgcatttgg aattaagatc aaaagggtac ttgataggac
     7081 gataccgatg atgaaatgat agacgcgtga gtggtagttg tttaaggcat aatccatcaa
     7141 ttttgaaaaa acgatgagag ttgcacctgc accaattcca atcggaaaga aggttcccaa
     7201 gagatcaaaa gttttaaaac cagtcaacat aggagcatag agtcccaaaa tcaaaagtaa
     7261 atttgatgga ctgaggccag gaaccaagac gccaagggcc aatagtgcgc ctgctaggac
     7321 gaagttaaga aagctggcgc ttaaggttcc aacgacaaaa tttaaggcat agagtcctaa
     7381 tccagaaatg ataaaggttg tccataacca agctaaatca atcttgtctc ggtcagattc
     7441 tcgagttgat tctttgagga ggctaggaac tgtaccgata atagctcccg caaagctcca
     7501 taatacaaaa acctgataat tttcaagcag gtattcaatc gggtaggaaa ataagccgat
     7561 tcccagaagc ataccgatgg caactggaat aaagtacaaa acattttctt taaagtcttt
     7621 aaagggatgg gccagaaagc caatcattcg ttcatagatt cctaagattg ctgctagaac
     7681 ccctccggaa attcccggta ggataaatcc aagagcaatt acaatccctt taataacgcg
     7741 tgctaaccat gagagcatat atttcctcca actatttcta tttcaaaaaa tccttactat
     7801 attgtatcac aatcagacac aaaaagaaaa agcaaatgat aaacaaatgc ttttaaggtt
     7861 ttaaaaaaag ttttcgaaag gtttcttctt tattttttaa gggagagata acgttgatat
     7921 ctaaatcgtg gtcaaagccg gcaatttttc ctttagatgt gtattggtga atatcataat
     7981 ctaaatcagt tttaggactg ctctccaaaa atcctgagtc tgagccgtag gacggaatcc
     8041 aaacagaggt aaacttgcct gtatcaatac tgtgttcttc catgaagtag acaccaacgt
     8101 agatgccgat gtttttagca cctagtgatg ctagttttgc tcgaaagttt tcgacacctt
     8161 cgttcatatt agacatggtt ttgtcttcca cgtcaagcca atagtaacta gggctgtaag
     8221 gagaggcagc attgtagaaa acttcggcag ccttttccat ttcttggaca ctttttccag
     8281 ctacataagc gtagacagca actgggacat tccgcttttg aagttcagtg atatgactct
     8341 tataggcctt gtctattcca ttgataaatg aagcatcatt ttcttttgtt gtttgagcac
     8401 cactgtgaac acgaacaata gcacctgaaa tattttgtga gagggcatcg tagttgattt
     8461 cctcaggatg ctgccagcca gagaggtcaa taatcggttt gtctaagtgt ttcaaagcct
     8521 gtgctatatt ggattttgtt ttaaacgatt ggctgtcatt aagtgggcga ttgatgatta
     8581 aaatgaacat cataatccca aaaaaactaa ataaaataag tggatgaatt tgttttctca
     8641 tatcttataa gtctacccta aaaatcaaaa aaaatcaaaa aaaatcaaaa aaatgggtta
     8701 aggaagagac tttagagcat tttttcattc aagagtgcgg aatgatttga aatatggtat
     8761 aataaaaggg aatttctaca gaaaagagaa gattatgtca aattttgcca ttattttagc
     8821 agcgggtaaa gggactcgca tgaaatctga tttgccaaaa gttttgcaca aggttgcggg
     8881 tatttctatg ttggaacatg ttttccgtag tgtgggagct atccaacctg aaaagacagt
     8941 aacagttgta ggacacaagg cagaattggt tgaggaggtc ttggctggac agacagaatt
     9001 tgtgactcaa tctgaacagt tgggaactgg tcatgcagtt atgatgacag aacctatctt
     9061 agaaggtttg tcaggacaca ccttggtcat tgcaggagat actcctttaa tcactggtga
     9121 aagcttgaaa aacttgattg atttccatat caatcataaa aatgtggcca ctatcttgac
     9181 tgctgaaacg gataatcctt ttggctatgg acgaattgtt cgtaatgaca atgctgaggt
     9241 tcttcgtatt gttgagcaga aggatgctac agattttgaa aagcaaatca aggaaatcaa
     9301 cactggaaca tacgtctttg acaacgagcg tttgtttgag gctttgaaaa atatcaatac
     9361 caataacgct caaggcgaat actatattac agacgtcatt ggtattttcc gtgaaactgg
     9421 tgaaaaagtt ggcgcttata ctttgaaaga ttttgatgaa agtcttgggg taaatgaccg
     9481 tgtggcgctt gcgacagctg agtcagttat gcgtcgtcgc atcaatcata aacacatggt
     9541 caacggtgtt agctttgtca atccagaagc aacttatatc gatattgatg ttgagattgc
     9601 tccggaagtt caaatcgaag ccaatgttac cttgaaaggg caaacgaaaa ttggtgctga
     9661 gactgttttg acaaatggta cttatgtagt ggacagcact atcggagcag gagcggtcat
     9721 taccaattct atgattgagg aaagtagtgt tgcagacggt gtgacagtcg gtccttatgc
     9781 tcacattcgt ccaaattcaa gtctgggtgc ccaagttcat attggtaact ttgttgaggt
     9841 gaaaggatct tcaatcggtg agaataccaa ggctggtcat ttgacttata tcggaaactg
     9901 tgaagtggga agcaacgtta atttcggtgc tggaactatt acagtcaact atgacggcaa
     9961 aaacaaatac aagacagtca ttggagacaa tgtctttgtt ggttcaaatt caaccattat
    10021 tgcaccagta gaacttggtg acaattccct cgttggtgct ggttcaacta ttactaaaga
    10081 cgtgccagca gatgctattg ctattggtcg cggtcgtcag atcaataaag acgaatatgc
    10141 aacacgtctt cctcatcatc ctaagaacca gtaggagcct atcatggagt ttgaagaaaa
    10201 aacgcttagc cgaaaagaaa tctatcaagg accaatattt aaactggtcc aagatcaggt
    10261 tgaattacca gaaggcaagg gaactgccca acgggatttg attttccaca atggggctgt
    10321 ctgtgtttta gcagtaacgg atgaacaaaa acttatcttg gtcaagcagt accgcaaagc
    10381 tatcgaggct gtctcttacg aaattccagc cggaaaattg gaagtaggag aaaacacagc
    10441 ccctgtggca gctgcccttc gtgaattaga ggaagaaaca gcctatacag ggaaattaga
    10501 actcttgtac gatttttatt cagctattgg cttttgtaat gagaagttaa aactatattt
    10561 agcaagcgat ttaacaaaag tggaaaatcc gcgtccgcag gatgagaatg aaaccttgga
    10621 agtccttgaa gtgagcttag aagaagcgaa agaattaatc caatcaggtc gtatttgtga
    10681 tgccaagaca attatggctg ttcagtattg ggagttgcag aaaaaataga ggaggtcagt
    10741 atgggtaaat ctttattaac ggatgaaatg attgaaagag ctaatagagg cgaaaaaatt
    10801 tcaggtcctc ctttgctaga tgataatgag gaaactaaga ttttaccaac ctcttcttcc
    10861 cgttttggtt atgccaatcc taaggatcat ggttttagcc aggaaacctt gaagattcag
    10921 gtcgaaccat ctattcataa aagccgtcgt attgaaaata ccaagagaaa tgtcttcaat
    10981 tctaagttga ataaaatctt atttgcggtc atctttctct tgattttgct tgttttagca
    11041 atgaaacttt tgtaatagaa aaggaattga aatgaaaata ggaattattg ctgctatgcc
    11101 agaagaactg gcttatctgg tccagcattt agacaatgcc caggagcaag ttgtttttgg
    11161 gaatacctat catacaggaa ccattgcttc tcatgaagtc gttcttgtag aaagtggaat
    11221 tggtaaggtc atgtctgcta tgagtgtggc gattttggct gatcatttcc aggtggatgc
    11281 ccttattaat acgggttcag ctggggcagt agcagaaggt atcgctgttg gggatgtcgt
    11341 gattgctgac aaattagcct atcatgacgt ggatgtcaca gcttttggct atgcttatgg
    11401 acaaatggcg caacaaccgc tttatttcga atcagacaaa acctttgttg ctcaaatcca
    11461 agagagttta tctcaattgg accaaaactg gcatcttggt ttgattgcta caggagatag
    11521 ttttgttgca ggaaatgaca agatagaagc gattaagtcc catttcccag aagttttagc
    11581 cgtggagatg gagggggcag ctattgctca agcagcgcat gccctcaatc tcccagtctt
    11641 agtcatcaga gctatgagtg acaatgccaa ccatgaagca aacatctttt ttgatgagtt
    11701 tattatcgaa gctggacgtc gctctgccca agtcttgttg acctttttga aggctttaga
    11761 ttaagcggaa atttgacagt ttttctagct tatgataaga tttaagtaaa gaaaagctag
    11821 aaaacgtttc agaggatatt atgagtattg aaatgaccgt cagtgagatt gcagaggtct
    11881 taggattatc tcgccaagca atcaataacc gtgtcaaaga attaccagaa gaagacacag
    11941 ataaaaatga caaaggggta acagttgtta ccagaagtgg cttgattaag ctagaagaaa
    12001 tctataaaaa aacgattttt gaagatgagc ctgtcagtga agatgtcaaa caacgtgaac
    12061 tgatggagat tctagtggat gagaagaatg cagaaattct tcgtctttat gaacaattaa
    12121 aagccaagga tcgtcagtta tcagaaaaag acgagcagat gcgtatcaaa gaccgtcaga
    12181 ttgctgagaa agacaaacaa ttagatcagc aacaacaatt gacccttcaa gccatgaagg
    12241 atcaagaaaa tcttaagcta gagctggacc aagcaaaaga agaagtccaa tccactaaga
    12301 aaggcttttt tgctcgttta tttggaggat aatcaaggag ctgtttaggt taaatgctaa
    12361 cctgatggct tcttttgttt gtgaatagta tagttgatta gaacagagac agtagaggag
    12421 aggtacagaa tggaacgatt agaagattac attgcttttg atttagaatt taatcagcac
    12481 gaaggacaaa cacacttgat tcaagtatcg gcagtgcgtt ttagagatgg tcgggaaatc
    12541 gatgcctatg attcctatgt tcataccagc gtccctctaa aaagctttat caatggtttg
    12601 accgggatta cagctgagac cttaaaagat gctcctccag ttgagaaagt cttagaagaa
    12661 ttccaagagt ttgtgggttc tttgctgatg ataggctaca atgctgctaa aagtgattta
    12721 cctattttag cagagcatgg tttagactat agccaacagt acaaggtgga tttgtatgat
    12781 gaagcttttg aacgtcggag ttcagattta catggtattg ccaatctcaa attgcaaact
    12841 gttgcctcat ttcttggatt tcaaggtcag tctcataata gtttagagga tgctcggatg
    12901 acggcgcgtg tttacgaatc cttcttagag tcggatcaag ctagggaatt gttagagaca
    12961 gaaagtagct tatcaaacaa tccttttggt ggcttggact tgtctcaatt atttgactag
    13021 gagtgcctat gaaacctgaa aaacctaaaa aattgggtct taaacagatt tacctcaatc
    13081 ttgataaaat cctctttcta tttttcttga tttttatgat agtggagtat ttgtgggtac
    13141 cattcaattc atggttggct agcttcttat tagatcagac aggttatctt tttatttcct
    13201 ataacaatgt cttagccatc cttactcatt ctccattgat tagtctagct tttttagcct
    13261 tgattgtaat taaccttctg gttgcttatt ttcaaatagg actcctcttt attggtgctc
    13321 gtcatctcct ctataatgaa aagcgaaggc taattgagta tatccgcaag gttttccatg
    13381 aaagttttgg atttatgaaa aagctaactg gcgctaaagc cttgtttatc tttttctata
    13441 tagctatgct ttttcctttt atacggaaaa tgctgaagat ttattatctt aataaaatcg
    13501 tcattccaga gtttatccaa gcttatttag aagataaata ttggatgtgg tggctgagca
    13561 tcctacttct atctcttatc tttctctatg tctctgtcag attgatgttt gcccttccga
    13621 agattgtata tgatcagctg actgttcgag aagcagtgat gtttagcttg gagaaaacca
    13681 agaagagagt tactttttat gcttggaatt tattttacat cttgctcaaa gcacatttat
    13741 tattttatct tcctttgatt cctttattat tggctcaaac tttggtagat gatatcactc
    13801 agagagagtc tctgattctt ggtattttga attttgtcgt gattaaaaat ctctattata
    13861 tggctctgac ttattttttg gttaaatttg tttcattttt gacaggaaag gagctggata
    13921 tgcttcctag gagagaaaaa gatcacatcg tgcgatgggg tgtcatgact tgtgccagtc
    13981 ttttctttgc cttagaaggt tatatttatc tggaggctcc catggttcat ctacctcaac
    14041 ttatttctca ccgaggggtt tccaatgcaa atgggattca aaatacagta gagtccttgg
    14101 aaactacagc acaactcaaa ccagacttgg tggagacgga cgtgcaggaa acaaaagatg
    14161 ggcagtttgt catgatgcat gatgctaact tgaaaaatct agcaggtatc aataaaagtc
    14221 ctcaagactt aaacttggag gagcttaaag ggattgatat ttttgaaaat ggctaccaga
    14281 ctaaaatttc aagctttgaa gattatctca gtcgagccaa cgaacttggt caaaaattac
    14341 taattgaaat taaaaccagt aaaaaagata gtccagacat gatgaaccgc tttttagccc
    14401 gttatgctgc aaagctcaag atttatggac atcaaatcca gtctttagac taccatgttg
    14461 tcgaaaaagt aagacagtat gatgccgaac tgccagttta tttcatcatg ccctacaatt
    14521 ctgtatttcc taaaacaaga gcgacaggat atactatgga gtactcaacc ttggatgaat
    14581 attttgtaag caaactatgg acaacggatc agaaacttta tgtctggact gtcaatgatt
    14641 cagaagctat cagcaaatct cttcacttag gagtagatgg agtgattaca gatgatttgg
    14701 aaaaagttca gcgggaaata gaagtagccc aagaagatcc agaatatacg gatttgctct
    14761 tgaaaaaagc attggaattc tttgaatttt agtaataaaa aagaggaact gttgttcctc
    14821 ccatgatagg taagtattct tgtgaatgct tgcttttttg tggttgcaat ccgtttacga
    14881 gaattgtttg tattgttctt gtttcaattt actttatagt gctttgaagt tggaatgcta
    14941 cactataact tctaaaatat agt
//
LOCUS       DBEJZV010000045        14919 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.45, whole genome shotgun sequence.
ACCESSION   DBEJZV010000045 DBEJZV010000000
VERSION     DBEJZV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14919
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.45"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(117..1541)
                     /locus_tag="ACL3S0_001861"
     CDS             complement(117..1541)
                     /locus_tag="ACL3S0_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR1312727.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="ACL3S0_001862"
     CDS             complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="ACL3S0_001862"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGR1312728.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="ACL3S0_001863"
     CDS             complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="ACL3S0_001863"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGR1312729.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRSLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6528..7706)
                     /locus_tag="ACL3S0_001864"
     CDS             complement(6528..7706)
                     /locus_tag="ACL3S0_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR1312730.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVCLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFFPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSLSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7786..8649)
                     /locus_tag="ACL3S0_001865"
     CDS             complement(7786..8649)
                     /locus_tag="ACL3S0_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR1312731.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8652..10553)
                     /locus_tag="ACL3S0_001866"
     CDS             complement(8652..10553)
                     /locus_tag="ACL3S0_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR1312732.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVEEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(10981..11256)
                     /locus_tag="ACL3S0_001867"
     CDS             complement(10981..11256)
                     /locus_tag="ACL3S0_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGR1312733.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(11363..12202)
                     /locus_tag="ACL3S0_001868"
     CDS             complement(11363..12202)
                     /locus_tag="ACL3S0_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR1312734.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            12344..13192
                     /locus_tag="ACL3S0_001869"
     CDS             12344..13192
                     /locus_tag="ACL3S0_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR1312735.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITTLIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(13285..14202)
                     /locus_tag="ACL3S0_001870"
     CDS             complement(13285..14202)
                     /locus_tag="ACL3S0_001870"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGR1312736.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVEQLKADEEVTRNWS"
     gene            14697..14830
                     /locus_tag="ACL3S0_001871"
                     /pseudo
     CDS             14697..14830
                     /locus_tag="ACL3S0_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
BASE COUNT         4522 a         3196 c         2589 g         4612 t
ORIGIN      
        1 tgtactattc tagtttcaat atactatagt accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctggttt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaattcct
      181 tgcactccag ctccagaacc tttgacacca aggaatggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attatcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg taaataagcc gcacgttcaa ctgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaatcacaa ccctttttgc aaaatttttg
     1621 agattatttt cacaaacttg atttttcaaa gtatactcaa taaaaataaa aaaaatccac
     1681 tacgtcaagg cgaggctaat gtggtttgaa gaaattttcg aagagcgtga atgagtatca
     1741 tctatagtaa aataaaaaaa ctgaacaatt tggttgggga cagccaaacc aatttctcac
     1801 aatgtttcag aaacaagggt gtgctactcc aatttcagcc tactataact gtcatagatt
     1861 gctgaaacaa agtctaggta aaagtcttca taataaaaag acctcctatc aagtgttcaa
     1921 aaactttgat aggaggtctt gttttgtgaa aatatttatc aaattttcta tacaagtgag
     1981 ctgttagcca ggttctttct attctttcaa tttcaatgaa tggatttttt actaatactc
     2041 ataactggga atttgtctgt gtaaaaatag cgagatagat ggtatttata aaacactcaa
     2101 gacagctaga ctaatatcat ttaaaacatt atcttctttt gagcgactgt tggttaccaa
     2161 catagctaaa tttcctgcat tttcaaattg atagggttct gatttagcat tcacaaccac
     2221 caagaggtgt tctttgccgt gaacttcata gataaggtag ccgctatgtt caatcgcaga
     2281 atgcacaaag acatgatggt aaatttcatc atagctagag taagaaaagg caccagtttt
     2341 tgtcttcaat cggatgactt gacggataaa ctcaatactg tcttgacgct cattaatcaa
     2401 gttccagttc acttggttca cactgtcagg agcattatag ctattcatcg cacgctctct
     2461 atcatcatgg gtcaactcac cattttcacc agtcgcaacc agtttggtac gaccaaattc
     2521 ttgaccgatt tccataaagg ccatcccctg catgagcaga ttcatggctg tggcagtttc
     2581 gaccttgcgc atgatttgct ctgaactttg gtctggatga agggttgcca ataaatcgtg
     2641 aagattgtaa ttgtcatggg cttctacata gttaagcacc tgatttggat gtgtatagct
     2701 tcctaattca cgacttccta ggattgcttt agctagaatt ggctctgtcg cagcaccact
     2761 gacaaaacct gacttgatag caccataaac ttctccccct ttgacagcat cgcgctgatt
     2821 gtcattaaag aaaccaatat ttggcatctg gtaggcattg tccttcttgg ccttatcata
     2881 aggggcaaga cctgttccca tatcccatcc ttctccatag aggataatgt tggagtcgat
     2941 ttcatccaag ctttgacgaa tcatctgcat ggtcttgaca tcatgaatcc ccatcaagtc
     3001 aaaacggaag ccgtcaatat tatattcctg cacccagtat agaagagaat caatcatata
     3061 cttgcgaaac atttcgtgtt cactggctgt ttcatttcca acacccgttc cattctggaa
     3121 ggtaccatct ggattcatac gataatagta atcagggact gttgtttgga atggtgcatc
     3181 aacaactgag aaggtatggt tatagactac atccataatg actccaatac ccgcatcgtg
     3241 ataagcttga accatcacct tcaaatcacg aatgacctga gctggatcat ctggattagt
     3301 tgaaaaacta gtttctggcg cgttatagtt ttgtggatca taaccccagt tgtaggttac
     3361 atttccatcc tcatcgtatt ctttatgacg gtctgcaatt ggttgcaatt gaacataatt
     3421 gtagcccagc ttcttgatgt aatcaaaagc agttgactgg ccgtattggt taactgttcc
     3481 agcctgagca gcacccaaga aagttcctcg aagatgttca tctacacccg atgtaggtga
     3541 tttagtcaaa tcacgaatat gcatttcaca gataactgcc ttacatggat tttccaagcg
     3601 ccaagtagcc tccgaaccgt gcttaacctc gaagttttca acttgctttt ctacatggct
     3661 cagaatagct gaacgtttgc catcagggct ggtcgcgatt gtataaggat cacgtgtcag
     3721 tgtttggtga tgagggaatt ggacttgata ctgataagcc ttacctacca aatcttcctc
     3781 aacatccaaa ctccagacac cgattgtatt gtccttatga ttataagagt agctattgcc
     3841 tcttttcatc tcaaaagtct tccaaacggg tgcatcatta gcagctgatt cataaacgac
     3901 aacttgcact tctgtcgctg taggtgacca gagggaaaaa tgagcctgat tgtcctctac
     3961 acggcaaccc aattctcctt ggtaacccca atgatggtca aaactagcac tgttaatggc
     4021 cttatcaaag gcaaaaggat tttgattttt atagaaagga ctggcaatag caggattttc
     4081 agagtaataa atcctatcat cgccttccaa aatccagacc tctgttaata ggggatagtg
     4141 attaaaacgg atagaatatt ctttactagt ttgacctgta tgaaccacaa aattcaagct
     4201 ttctataaca tgtgaacttg ggtgttcaaa gctaaataaa gctccaaaat aatcttcttt
     4261 gtaggttagc aaatcaattc gttgatcctg actttttaca aaggagcaag tgtcatattc
     4321 tccattctta cgatggtaat gaatgcgcat agggtagtta tacatttttt atttttcctt
     4381 tttactttgt ttctatttca ctaataaatt tttgtcaatc tcgtctcaat taacagacat
     4441 agtcatattc tctaaactct gtttttaaac gatccattac aaactttcta gccatgcctc
     4501 atctctgacc tggataccaa gttcttgtgc tttttgcagt ttacttccag cgtctgcacc
     4561 taccacgacg aggtcggtct ttttagaaac actacctgtc actttggcac ccagactttc
     4621 gagtttactt ttagcttctg agcgcttgag tcgttccaat tttcctgtca ataccacggt
     4681 caaacctgac aaggccgcat ccgctactac cgtctgtcct ttatagtcca gattgacccc
     4741 agtttctttc aattctctga gcagaatttc agagccttct gtcgcaaaat aagtctgaag
     4801 acttttggca atcacgccac ctagactttc aatactagcc acttcctctg aatctgcctg
     4861 agacagattt tcaattgaat ggaaatattg aagtaaaagc tgactagcct tgcttccgac
     4921 atgacgaatt cccaaaccaa ataagagctt ctcggcagaa ttttcctttg atgcttggat
     4981 agcctgatac agtttagcag cggacttttc cttaaccccc tctaaaagga ggaaatcctc
     5041 ttcttgcaaa cgataaatat ccgccacatc cttgactaaa ttagcagcaa aaagcttctc
     5101 aacaatagat ggaccaaggc ctgtaatatt catagcatca cgagaagcaa agtgaatcaa
     5161 gccttccatg atttgagcag ggcaacgcgg attgatacaa cgtagggcca cttcatcttc
     5221 aaagtgcaac aagtcagagt tacaacttgg acagtttgta gggatatcta gtttttcttc
     5281 agaaacccgt ttggactcta ccacacgtaa aacggcaggg atgatgtcac cagccttata
     5341 tacaatgacc gtatcgtctt ttcggatatc tttttcagca atataatcta cattgtgcag
     5401 ggtcgcacgg ctaacagtcg taccggcaag ttgtactggt gttagattag cagttggagt
     5461 tacaacaccg gtacggccaa ctgtccagtc aactgataag agttgagctt ctttttcttc
     5521 ggcagggaac ttgtaggcta ctgcccactt tggagcctta actgtaaaac caagttcttc
     5581 ttgacttgct aggtcgttga ccttgattac cactccatca atatcgtaag gcagattttc
     5641 ccgttcctgt cctacttctt ggataaaatt ccagatttca tctatgtttt cagccaagat
     5701 tcgcttagga ttgaccacaa aacctagttg ttctaggtac ttcaaaccct tttcttggct
     5761 atcacgagtt gaagggctgg cttcttgata gagaaacgtt gcaagactac gcttggcaac
     5821 tactgctgta tccaactgac gcagagttcc tgctgccgca ttacgaggat tagcaaattc
     5881 aggctctcca ttttcttggc gcacttggtt aacttggtca aaggaagcgc gtggcatgta
     5941 acattcccca cgaactgtga tatctagttc ttctggcaaa gtcaaaggga tgtccttaac
     6001 acgcttgagg ttttctgtga tattttcacc aattgaacca tctccacgtg ttaccccagc
     6061 aaccaaaatc cccttttcat aagtcagcga gatagataag ccatcgattt tcagctcaca
     6121 aatataggtc ggatgagcca cttccttacg aacacgcgca tcaaaagcat ctagctcctc
     6181 acgtgaaaaa gcatcctgca aactataaag aggatactga tgactgtatt tttcaaaacc
     6241 atctaaaacc ttgccaccaa cacgatgagt cggactgtct gctagcactt gctctggata
     6301 agcagtttct aactcgacca actcacggta aaggcggtca tactcactgt ctgaaaccga
     6361 gggattatcg ctggtatagt actcagtcgc atagcgattg agcaaagcga ctaactcatt
     6421 cattctttta ttcataagac cattttacca taaaacaagc cctcctcaca aacgagaagg
     6481 gcggaaaaaa cacttagttt gaaattattt ttgaaactca agcaacctta tatcaatttt
     6541 tcaaaatgag ttcgaacata aataaacgat atacaagaca agatgataac accacttcca
     6601 attatcagga aagaagagag atgtacactt ggcaagactg tcataaatcc ttttgcaata
     6661 ggcataaata gaatagctaa ggtaaaaatt gtactcagta ctctcccaag aaattcgctc
     6721 tcaaccttgg tttgtacttg agtaaaaaag tgaatattaa aaatcgtcat aaacaattca
     6781 caaactaaat ttccagaaag ggaaagaaaa gttggaagtg gtaatcccat cataaaaact
     6841 ccgacacctg tcaaagccag taaaatcaaa agattataaa tattagcttt aattttacta
     6901 gctagaagag ccccaatgat ggaaccaata gcccccatag ttaaaatact tgcataggct
     6961 ccttctgacc cgtaaagctg attcgaaaag ggaagtagaa attcaaaagc tgcaaaaaag
     7021 aaattaacgc tggaagctac cagcaaaagg aagaaaattt cttgctgatg ccagatatag
     7081 tgtaacccat ccttgatatc tacaaaaata tctctcccag taaaagcctt tttctcttga
     7141 acttttgctt cctcttttgg aaagaaagcc actagaacaa aagcaatgaa aaaagtcagc
     7201 gagtctagca gtagcgtcat atggagactt gcaaactgta aaacaaggaa ggaaagaaca
     7261 ggagagctaa cacctacaac ctgcaaaacc agctctaggc gagaattata gatcacaatc
     7321 tcatctttct ccaccacttc agttatgata gctttattgg ctgtgcgaga aaaggcaaaa
     7381 gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa tcatccagct atcattcctt
     7441 atgaaagaaa tagccagaca aagaatccca caaacaagat ctgccgtcat taaaatctta
     7501 cgacgagaaa aacggtctga aataactccg ccaaagggat tgacgagaat agatgtgacg
     7561 agctcagaaa tctgatacat tcctaaaact gtctgtccta tagtccccat agaagccaag
     7621 cagacactat ttccataatc atagagcata tttcccattt tattgatagc cccacggcta
     7681 atcaactgca ctgcatagcg attcatatta aagctcctct caaattttga aactattgta
     7741 tcaaaaccga aaggagcttt ttattttttc ccttatttgg gaaaattaac ttttgacaaa
     7801 tttttcgtag tgttcctgat aataggctac ttgctctgga agacctaaca catcaaaaat
     7861 atgtatggcc tcttgcatct gcttacagcc ttctttacac tgtccttttt gatataaggc
     7921 aaaacctttt aaataatgga aaacattacg ctcataaagc ttaatacctt tgtcaataat
     7981 cttctctgta taagcctcaa aatagttggc attataaaaa gaagaatgct ctaaacaatg
     8041 ctggtaacaa ttgagggcca aaatcaacac taatctctta tggcgactaa tctcttggta
     8101 aaattcctcc ctctccataa cttctctacc aatccgagtg acatagtcta catcgtagaa
     8161 actatagagg ttaccgaaaa gaatcaactc atacatggtc cattcttctg ttttgaagag
     8221 ataatctgct accttatcca aatcatcctg cttcatatca taactcgcat ctctttgaca
     8281 aatcagacct tgtagcaaaa tccagttcag ctcaaaataa agggaagtcg tcgaactctt
     8341 agacttttca agttgttctc tttgaagctt ttgaaaacct gcaatatcgt ttgaatagta
     8401 aagtgggata atctgtgcca tcatagacac atgttcatga ttatgaaaat tccttgcctt
     8461 atccatgaaa ttttcgattg ttacatgaat gttatccaaa atctcaaaga aacgggagac
     8521 tgccaggtca gactccccaa gctcaaagcg agataactga gaggtagagc aggattcgcc
     8581 tgctgcttcc tttaaagaat aatttccact tgttcgaaat tcacgaaata cttttccaag
     8641 atgttccatc tttacacctg atctgataat tcttcccact caagcatagc ttcttcctga
     8701 cgatggctga ttttgtccag ctcagcctgt aattccatga gtttgtcggc atcgtttgtt
     8761 tccaacattt gttcagaaat ggcttggctt tgactttcta gctcttcaat ttcagcttct
     8821 agactttcga tttgtcgcat gagtttgcga acttcttttt gactttcttt ctgggcctga
     8881 tagtcattga ctggacttgc ttcctttgct tgattgctag ttgaagcttc ctcagtctga
     8941 ctcatttctg ctgttgcttt cttctcaaca tagtagtcgt aatctccaag gtagagagtt
     9001 gaaccattct cagacaattc caaaacatga gttgccacac gattgataaa gtaacgatca
     9061 tgactgacaa aaagcaaggt accatcaaag tcaatcaagg cattttctag cacttcctta
     9121 ctatcaatat ccaagtggtt ggtcggctca tccagaatca aaaagttatt gttttccata
     9181 gacaatttag ctaaaagcaa acgagctttt tcgccaccag atagcatgcc gactgatttt
     9241 ttaacatcat ctcctgagaa aaggaaggct ccaagacggt tgcggatttc aacttctggt
     9301 gtcagtttga aatcattcca gagttcatcc agcaccgtat tacttggtgt cagcttgctt
     9361 tgggtttggt catagtaacc aacctcaaca ttagcgccaa agcgcttttc tcccttgata
     9421 aacggaattt gatccacgat tgatttgata aaggttgatt ttccgatacc attgggacca
     9481 acgatagcaa cagcattcat cttacgaagg tctaggttaa tcggttgtga caggacttcc
     9541 ccatcatagc caacagccgc attttcaaca gtcaaaacaa cattgcccga cgttttttca
     9601 gactggaagg tcatgttggc tgctttcttg ccagcttccg gcttgtccaa acgctccatt
     9661 ttttctagtt gtttacggcg agattgagca cgtttggtcg ttgaagcacg aactagattg
     9721 cgattgacaa agtcttccag agcagcgatt tccttctgtt gcttttcata gttttttgcc
     9781 tcagtagcta gcttttgctc cttcaactcg acaaaacgag agtaattccc cacatagcga
     9841 tccaaggaat gcttggtcaa atctagcgta attgtcgcaa ccttgtccaa gaaataacgg
     9901 tcgtggctga cgataatgag ggcaccgcta tagtttacca agtaattctc tagccaggag
     9961 atggtttcaa tatccaagtg gttagttggc tcgtccaaga ccaagagatt gggcttttca
    10021 aggagcattt tagctagagc caaacgagta ttttgaccac ctgaaagttc agctattttc
    10081 atctgccaca tagactcgtc aaacttgaat ccattcaaaa tcgctcgaat atcagcttca
    10141 taggtaaagc cgcctgcttg gcgaaaattc tcagataagt ggtcgtaatc tgacatcagt
    10201 ttatccaatt catcgccaga cttttcaccc atctccaact ccatctgacg aagttgttta
    10261 tctgtccgac gtaagtcatc aaagacatga agcatttcat cgtagatggt attttcagac
    10321 tcaaaacggc tatcttgggc taggtaagac agagaaatat cttttttctt attgatttct
    10381 ccgctagttg gctcctcttc ttcaactaaa atcttcaaaa gagtagactt acctgcacca
    10441 tttttcccaa caagagcaat ccgatctcgt tcatcaacct gcaggttgat attatcgaaa
    10501 agaacctctc ctgcaaaaga acgttcaatt ttattagctt gtaaaataat cataagagta
    10561 gtatagcatg tttccctaag gcattcaaga taatcgtaag tcttttagta caacttttat
    10621 aacataaaat aaactaaatt atgtatattt tatattagat tccttcacta tcttgttgga
    10681 ttttctaacc agctaatctt gtttcaaata gttatcgcac aagtctatta tttaattctt
    10741 ttcatcattt acgtacgtat agcagattga aataagatga gaacaaatcg attgggaaag
    10801 taaaattaat ttctataaat gttttagcaa ttgtttcgta ctattttaga ttcagtctac
    10861 tatatataca atattttcgg aacattcaac tttttaactc tatttattac tagatttcat
    10921 aattaaaaag cctactgacc aagctagaaa gcttgataca ataggctttt taaagactga
    10981 ttatttaaca gcgtctttaa gagctttacc agctttgaat gctggtactt tagaagctgc
    11041 aattgtcatt tctttaccag tttgtgggtt gcgaccttta cgttctgcac gctcacgaac
    11101 ttcaaagtta ccaaaaccga tcaactgaac tttttcacca gctgcaagat agtcagctac
    11161 tgctgcaaat acagcttcaa ctgctgctgc tgagtctttc ttagtcaatt ctgtagcttc
    11221 tgctacttta gcgatcaaat cttgtttgtt tgccatgtta atgattcctc caaataattt
    11281 ctaattaaca aatataatca tatcctaaaa tcccttttag gtcaagttaa aaacgctatt
    11341 tcttcccatt ttatttattt ttttaggagt ggtaacgtat caaaatagcc caagcgttct
    11401 cacccgtgtg agtttgaata atggaacccg tttccaaaac agaaattggc ttttcaacat
    11461 aagcttgtaa gctttctttc atctcttttg cccaatcatc actaccagaa tatgaaattc
    11521 caatctctgc tacagcacgt tcagaaagcg atgttatcaa ctcatctaac cattttttaa
    11581 atgttttagt tccacgacct ttaaccattg gctgcaattc atggtctttc atttgcatga
    11641 caacacggat attgagaaga gagctcaaca agccagttac acggctaatt cgtccacctt
    11701 tgacaagatt ttccaaagtt gaaacaccaa tataaagctc tgtatggttt ttaacctctt
    11761 ctacatgaga taaaattgcc tccatatctt taccttcttg agctaacttc gcagcctcaa
    11821 caacttggaa tttcagggct tggtcagtga aggaactatc aacaacagtc acatctgcag
    11881 tagataggct agcaccttgg cgtgctgctt ctaccgtacc cgaaagagca tgggacatat
    11941 gaatagcaag aatctggcca ccatctttgc ataggtcttc aaaaatctca gcaaagacac
    12001 ctacaggggg ctgacttgtt ttcggaagat tcttactttc ttgcatcaac tgaagaaatt
    12061 taccttcttc tttcaaatcc gcatcagaat aaacaacatt atcaatcatt acagataatg
    12121 gaacaattgt aatatctaat tgctttacta gttcaggttc aatagtaaca gatgaatcgg
    12181 ttacaatctt aatttttgtc atagtatcaa tctttctatt ttaggattca gattggtttc
    12241 cttacttcta attatatcaa aaaaaagatt aaaaatccta atggagtcaa tcaaattttc
    12301 cgtaaaattt gatataatca acttataaga aaagaggtgt cctatgatta aaaaaattta
    12361 ccccattttt accattttac taggtgctgc tatttatgct tttggactga cttattttgt
    12421 agttccccat catctctttg aaggaggggc gacaggcatt accctcatca ccttttatct
    12481 ttttaaaatc cctgtttccc tcatgaacct gctgattaat attccccttt tcatcctagc
    12541 ttggaagatt tttggagcca aatccctcta ttctagttta ctaggaacct tagctttgtc
    12601 cggctggtta gctttttttg agcatattcc ccttcatatt gatcttcaag gtgatttact
    12661 aatcacaacc cttatagcgg gaatcctatt gggaattggc cttggaatta tttttaatgc
    12721 tggaggtaca actggcggaa ctgatattct agctcgtatt ctcaacaaat acactcatat
    12781 atccatagga aaactgctct ttatcttaga tttttgtatt ctcatgttga ttctcctaat
    12841 cttcaaggat ttgagattgg tttcctacac gcttttgttt gattttattg tttctcgtgt
    12901 tattgatttg attggtgaag gaggatatgc cggcaaaggc tttatgatta tcacaaaacg
    12961 tcctgaccaa cttgctaagg cgattaatga tgacctcgga agaggtgtta cttttatttc
    13021 tggtcaaggc tactatagta aagaaaattt gaaaatcatc tactgtattg tcggaagaaa
    13081 tgaaattgtg aaaacgaagg aaatgattca tcgaatcgat cctcaagcct ttataactat
    13141 tacagaagcc catgaaatcc taggagaagg cttcaccttt gaaaaagaat aaaaagaggt
    13201 agtgtcgtga cctcaaaagt tagactaaat catctatctt ttgggttaca gacaacctct
    13261 tttttgtttt atttactcaa gctcttaaga ccaattccga gttacttctt catcagcctt
    13321 taactgttcc actaattggt caactgagtc aaatttggtc atatcacgaa tgcgatcaag
    13381 ccaataaacc atgacggttt ccccataaat atcttgatta aaatcaaaaa tattgacttc
    13441 aaaacgtgct tcttctccat caaaggtcac atttttcccg acactagcca tagcacgata
    13501 cttctgtctt tgaatctcaa catcaacgac ataaacgcca tctgctggca tataagtacg
    13561 gtctaaaagc actaaattcg ctgtcggata accaattgta cgaccacgag cattaccatg
    13621 aaccaccata cctcttgatg gaagcggtgc ccccaaaagt tttcctgctt ctttcacatt
    13681 tccatctaaa atagcttgac ggatacgagt tgaactaatc tttcctttct catcttctac
    13741 aggtggaaca atgataactt ctccatcaaa gtaatccttt aaatcttctg ctgttttttt
    13801 gtcagaacca aatgtataat caaaacctgc aacaataatt ttggcattca tagccttgat
    13861 ataagttgca aagaattctt gtgcagtgag actagcgaat tgactactaa aatcaaggag
    13921 atataattct tctacacctt cgcgctttaa ttttctttca cgttcagcag ggttcaaaat
    13981 atgcaaaaac aaatctggat gataaggctc taaagcgatc tttggagatt cattaaaggt
    14041 cataacgacg ataggtaata aatcctttct cgcagccttg ttggcaacac gaaataattc
    14101 ttgatgcccc ttatgtatgc catcaaaata gccgagaaca acgactgaat cagatggtgt
    14161 gccaatatct ttttggtttt ttataggaat agtaataatc ataaaataat tatatcatag
    14221 cgatagctat ttctggaaca gaaaatctga aatgttgttt ttttcacatg aagtgtacct
    14281 gttttcaaaa agcactttat tctatcgttg cttaactatg aactttgcaa tattcttctc
    14341 aaaaacttgt aggacatctt caaaattttg caaggagtga ttagacttgt tcggtaacca
    14401 taaagtgtca tactatgctt atgtatgaaa aagcaatgca actaactcct gagaacttta
    14461 aattactaat tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa
    14521 atttacaaaa tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt
    14581 gaagcaagtc actttccctg atgacaaaga aaaaagccaa aacagcaaag aaaaactaga
    14641 tgactgcttt ccaacaactc ccatctagtg tgcttcagac taggctattt ttctctccat
    14701 ctgttagctt ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg
    14761 aacggctcaa accattcaga caagtgaagg gacgacaagc caatatttga aaccagatag
    14821 cagttcttat agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat
    14881 ttttaacagt gttctattcc agattcatac tcaatgaaa
//
LOCUS       DBEJZV010000046        14876 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.46, whole genome shotgun sequence.
ACCESSION   DBEJZV010000046 DBEJZV010000000
VERSION     DBEJZV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14876
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.46"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(697..1329)
                     /locus_tag="ACL3S0_001872"
     CDS             complement(697..1329)
                     /locus_tag="ACL3S0_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312737.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(1331..3346)
                     /locus_tag="ACL3S0_001873"
     CDS             complement(1331..3346)
                     /locus_tag="ACL3S0_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGR1312738.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLTTSTEWHDY
                     SPNGNVLIVTPHYLERQNIPVDTTIKQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            complement(3796..3966)
                     /locus_tag="ACL3S0_001874"
     CDS             complement(3796..3966)
                     /locus_tag="ACL3S0_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HGR1312739.1"
                     /translation="MKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVVKAD"
     gene            4155..5018
                     /locus_tag="ACL3S0_001875"
                     /pseudo
     CDS             4155..5018
                     /locus_tag="ACL3S0_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            5401..6021
                     /locus_tag="ACL3S0_001876"
     CDS             5401..6021
                     /locus_tag="ACL3S0_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312740.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            6107..6550
                     /gene="tsaE"
                     /locus_tag="ACL3S0_001877"
     CDS             6107..6550
                     /gene="tsaE"
                     /locus_tag="ACL3S0_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGR1312741.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            6540..7058
                     /locus_tag="ACL3S0_001878"
     CDS             6540..7058
                     /locus_tag="ACL3S0_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR1312742.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVCHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            7066..8082
                     /locus_tag="ACL3S0_001879"
     CDS             7066..8082
                     /locus_tag="ACL3S0_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGR1312743.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            8167..9423
                     /locus_tag="ACL3S0_001880"
     CDS             8167..9423
                     /locus_tag="ACL3S0_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGR1312744.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            9478..10644
                     /gene="recA"
                     /locus_tag="ACL3S0_001881"
     CDS             9478..10644
                     /gene="recA"
                     /locus_tag="ACL3S0_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGR1312745.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            10951..12321
                     /locus_tag="ACL3S0_001882"
     CDS             10951..12321
                     /locus_tag="ACL3S0_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR1312746.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKQPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            12697..13653
                     /gene="lytA"
                     /locus_tag="ACL3S0_001883"
     CDS             12697..13653
                     /gene="lytA"
                     /locus_tag="ACL3S0_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGR1312747.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(14286..14876)
                     /locus_tag="ACL3S0_001884"
                     /pseudo
     CDS             complement(14286..14876)
                     /locus_tag="ACL3S0_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4550 a         2683 c         3030 g         4613 t
ORIGIN      
        1 ggtgttcaag ccaattgtaa agcgaaagga gaaaaatatg gcacaaaagg ttcttttgtc
       61 ctgttcttgt ttcaattgac tatatttcta tactttttct tcctttctct gtgaaaatcg
      121 caagtttttc ccaccttttc tcaatactga aacaacatct ttccagaact tcaataattt
      181 ctttttgtgt taaatcatta tttaactaaa tctttggagg caatacgttt tcaaagcgac
      241 ttttttacca taggttttga gccttcaaca cagattacta agccaaaaat gctctaaatt
      301 tttgaaattc taacaaattc cactcaactt tatcatcatc tttgactttc acaatatctt
      361 cctcaaaata acatggaata aagatagttt tcttttaaaa cggttgtagg aggaaaatct
      421 ctcctacact attattgatt ctgagagaaa attgcaaaat atcatctacc aaactttcaa
      481 ttattaagat tttttgcagt ttatctgaat tagaatcgca aggcttctca ataatataat
      541 tgtcgaattt tttcattcta acttcctctc cattatttct tcctttatca agaaaaagtt
      601 acctcaatat taataaagta caattctaaa ttaactccaa ttattgattc atgataatat
      661 ttcagtaact catcgtgcaa ttaaaaacaa ggatttttat ttcagatgat ccatcgtgaa
      721 cacttcatca gccatctccc aaattgccgg attatgtgtt gcgataatga ttagcctatt
      781 atcatctcga agagatagca aaatctccat aatcaactga gaggttgctg ggtctattga
      841 agctgttggc tcatctgcca gaataaaggg tggattcttt aagataattt ttgccaaggc
      901 aacccgttgc gattctccgc ccgataactc aaagatgcgc ttatctaggt caagataagc
      961 caggccgacc tgttctaaag cctgcttctg cctcaaccgc tgttccgacc gactcaactt
     1021 ttgaccaatg agacctagct taaggttttc ttcaatactt tggttttcaa ttaagccaaa
     1081 gttctggaag aggtagccca attcgtgacg gaaaaaatca ctcgatttat aattggccaa
     1141 gtctttacct cggtaaaaaa tcgtcccatc ataaggttct aatttcccaa tcatgttcat
     1201 caaggttgtt tttccgctac cacttgaacc aattaaggca tagacttttc cagcctcaaa
     1261 tgtcattgaa agattcgaaa ataactctcg ttctccaaaa gatttactca cctgtttaag
     1321 ttcaatcata ttaacctccc ttcaaaacaa gaatggacat cttgttttct ttctgcattt
     1381 ggacatgtaa ctgtaaaaga gatagaccag taaagagtaa caagactaag aaagcaactc
     1441 ctatctctac ctgaagaaat acactcgcaa caaatcccag taaaaacaca cccagttgag
     1501 caaagagata agtgcgatgg atttctaaga acctgagacc tgcaatgcgt ttgataaaaa
     1561 tggcacgtct aaattcttca aagtagagcc tattcatagt gttaaacaac aagattgaag
     1621 ttgcaatccc aagcacagct cctgctagca ttacccaacg ttccctctgg atattatcca
     1681 ataatgtgat gtagttgtgg taacctgttt gcatttctga gacccaattt tcaatgcctt
     1741 gtctctggat aagctcctgg gcatcagaca attgattaaa gagaacgtag ttctgtactg
     1801 cgtctatcca aaacaaaatg gactgtggac cagttgattg gggtgttata acaatgatga
     1861 ttggatcttt caaaaactgc tggtaagaaa taggggtcgt attatacaca aaacgatcct
     1921 gacctgattc taaataacct accgtagcag tcatttgctg tcgttcatct tgactagaca
     1981 tgcgactggt taagtcgtct tcaaaaacag atttataatg ttcttcctct gaacggaggt
     2041 gttcaggcag caataagaca aactccccta cattaaggtg attcatcttt tgcttaatag
     2101 ttgtatctac aggaatgttt tgacgctcca agtaatgcgg tgtgacgata aggacattgc
     2161 cattcgggct gtaatcgtgc cattctgtag aggttgtcaa gtttttggag gaagccatgc
     2221 cattttgcaa agtacggtca attaactggt gtctagataa gaaagccttt tgttctgaaa
     2281 cagccagatc catcaattga taccaagttc tgagtttcct ttgagcttgt tcatcaaaac
     2341 caggactcgt tccttcacgg ctgattgata gggtaatcag ttgtctttcc tgactccaaa
     2401 cctcttgtcc aatccgatgc tgttgccagg cttgggaata ctttaagcta ctccctattc
     2461 ccagcgttac aataataatc gctaacagtt gaccgattaa aatcaaacta atgattcctc
     2521 tgacaggcac ttgccctttt ataatctgca tcaggtgtat cttttttatc ccaactgcga
     2581 agagttgagc gaaaaacagg gagatcgaca acaagatgag attataactg agcaagcctg
     2641 ctcctatggt cattagggat tgcgttggaa gcgacagaat tttttgcata agaatggcga
     2701 gcacgccagc taaactgaaa ccaacagcta tccctttcaa atcctcacca actggtctaa
     2761 ggaaaatgga ccaccgtttc tctcctgaaa tgaggcgaat gcccgatgac cgtaattggc
     2821 taatttgact aattaaagtc agtgctacaa aggttaagat gaaaatcaat agactgatta
     2881 actgaaatcc gttactaaag atagccatta acgtagatag tttagatgga attgtcaggt
     2941 gcatgttagt caagccaagt tgacttagct cttcccttag caagtgaata tctaggtgtc
     3001 catcgaatac aaaatagttt gtttcaacac tactactttg agcatcttct agattttttt
     3061 cctgaagccc atcaggcaac tttccgtccc caaaggtcgt ataagaaaaa actgtagtac
     3121 cttctgagtt aggatcttgg tgttgaatcg caataaagct atctgtttct tctgctagtt
     3181 tttccaagcg tgtagcaaca tgctgaaaag ttgtttcagg ggaagaatca tgtacaacaa
     3241 cgttggggta ataataggag acatatgtat cagtccaaat ggtaaatacc caaacaaaga
     3301 acaaactagc aagcaggttg gatatgagta taaataattt tttcatagtg cattccttat
     3361 tctaaaacag agggcagaaa tacccctgcc ctctataaac taacaagctt actaaactat
     3421 tgataaaaga atcttcttca attattcttt accatcccgc atcaaatcta aattttaaca
     3481 tattattact cctctgaatg aaatattatg aaaatgagcg aaatgcaact acatatttta
     3541 attagaaatc tcagtctgaa ttatagtatc ctattttttc ctcctttcta actgcacgtt
     3601 cctttctaca ggcagagacc taattttata aaccaatctt aaatacttta gattttgtaa
     3661 ctcataattt tcaacagttg gttagctatg aaagcatttt atcaaacatc tccattctta
     3721 tatctatctg gtattgttac aagctctcat cagaatacct ttctctaaat agttgaattt
     3781 taaagtaata cgaaatcaat cagccttcac aacatcaaga ccattggact tcttttgtga
     3841 ttgcactcga atctccaatt gtctattctt ctgaataaac tgttggtaag gaattgtgtt
     3901 actaaacata aaaacaccta gtaatactaa tatagctaat ttttgaattc cacgattttt
     3961 cttcattcgt gaaacccttt tctttttcct tgtttttatt ttaatatata tatattattc
     4021 ggtcaagcat ttttatgtaa tttttgactt tttttagttt attaccataa agaattattt
     4081 atttctttaa cttgctattt tgaactaaaa attttataat gcaattaagc aaataggaag
     4141 gtttattatc tttaatgagt acactcgcag agaaattcag attgaaaaga aaagagttga
     4201 gactctccca acaaactctt gcagaaggaa tttgtgaaca aagccagatt agtaaaattg
     4261 agagagggca tttcattccc tccgcagacc ttttgttcaa actctctcaa cgacttgaag
     4321 taccattaga ttattttttt aatgaacaaa ttgaaattaa atctaacctc tctaatttca
     4381 agcaattgtc tgctcgacta ttagacgata gaaattatga cgatttggaa tatatttata
     4441 gaatagagat tgaacgaagt acttttctaa cactagaaga ccgaacttac cttgaatgga
     4501 ttaaagctat tattgacttc tatcaatatg acagtaagtg tgaggcaatt tcttcattgg
     4561 aaaatatatt attaaaagtc tcttcaaata ctctgattta tttaaaggcg ttgaatactc
     4621 tatctaattt ctattcctta gtgggtcgtg aacaagaata tgaggcaaac tactctcatt
     4681 taatagagtt gtatcagaca aaaaatttgg accatcaaga gtttttattt ggctacatca
     4741 gagttcgtta caactacgct cactacctag tatcaaagga aaaatataat gaagccatct
     4801 aagaagctct tgaaacgatt gaactctgta aacaaagata gacaagctac caattggctc
     4861 ctctacttat tcttgtagga aatgctggag ccaaatttct agacagagaa caagtcaaaa
     4921 attattatat agaagcaaga gagctatgca agatttataa caatccttta atgctgatga
     4981 agatagaaaa ttatttgaag gaactagatg ctgtttagtt tatcttgata ttggagtgtt
     5041 acttaaacat taaatagcct gtaaggctga tagttagatt aatactatca gccttataat
     5101 tatgtgactc tgagtccgtc tcgctccgtg aggtgcgaga caaaacaacc acccgtttga
     5161 cggattttca tgatttcaaa tttatattct tcgaaaatct cttcaaacca cgtcagctct
     5221 atctgcaatc tcaaaacagt gttttgagca acctgtggct agctacctag tttgatcttt
     5281 gattttcatt gagtattagt ctctagtgtt tgtttagcgt cttaaagaga catttgagaa
     5341 gattagaaac agttctctct tttctcctag tataatgatt ggtaggaagg gagagagaag
     5401 atgaaatcaa tgagaatctt atttttgtta gctttaattc aaatcagttt gagtagctgt
     5461 ttcctatgga aggaatgcat cttgtccttt aaacaaagta cagctttttt catcggaagc
     5521 atggttttcg tttcaggaat ctgtgctgga gtaaattatc tttatacccg taagcaagaa
     5581 gtccatagtg tcctagccag taagaagtcg gtgaagcttt tttacagtat gttactctta
     5641 attaatttgt taggagctgt tcttgttttg tcagataact tgttcatcaa aaatacgctg
     5701 cagcaagaat tagttgactt tttattgcca tccttctttt tcctatttgg gctagatttg
     5761 ctgatttttt tacccttgaa aaaatacgtg cgcgattttc ttgctatgct agacagaaaa
     5821 aagacagtgt tggtgactat tttagcaaca cttcttttct taagaaatcc aatgaccatt
     5881 gtctcacttc tgatttatat tggattgggc ttgttttttg cagcctatct tgtcccaaat
     5941 tcggttaaga aggaagtttc cttttatggt catattttcc gagatcttgt attggtcatt
     6001 gttacgctca ttttctttta gagaaagcct gttttttatg gatgttatga tgataagttt
     6061 agtaggaaaa tagacacaaa agaaaagttt ttggtataat aagagtatgt acacaaaaaa
     6121 tgaagaagag ttgcaagcct taggggagcg tttgggccat ctattagcaa agaatgatgt
     6181 tttaatctta actggagaac tgggtgcagg taaaacgacc tttactaaag gacttgcaaa
     6241 aggattacag atttctcaaa tgattaaaag tcctacctat actatcgtga gagagtatga
     6301 aggtcgactt ccactttatc acctagatgt ttatcgtatt gaaggagatg ctgattctat
     6361 cgacttggat gagtttatct ttggtggcgg cgtgactgtt attgagtggg gaaatctctt
     6421 aggagatgcc ttgccagatg cttatttaga attggaaatt ctaaaagaag cagatggacg
     6481 ccgtttaaat tttcaggcaa agggtttgcg tgctgagaaa ttgttagagg agcttcaata
     6541 tggagtatga attgctcatt agggaagcag agcccaaaga tgcagctgaa ttagtggcct
     6601 ttttaaatcg tgtgagtttg gagacagact ttaccagcct agacggagat ggtattctct
     6661 tgactagtga ggagatggaa atattcctca acaagcaagc tagttcggac aatcagataa
     6721 ccttacttgc attcttaaat ggcaaaattg ctggtattgt aaatattaca gctgaccagc
     6781 gtaagagagt ctgtcatatt ggagatctct tcattgtgat tggaaaaaga tattggaata
     6841 atggcttggg aagtttgttg ctagaagaag cgatagagtg ggcacaagca agtggcattc
     6901 tgcgtcgtct ccaactgact gtccaaactc gtaatcaagc agcagtccat ctttatcaaa
     6961 agcatggctt tgtcattgaa ggtagccaag agcgtggggc atatatagaa gaagggaaat
     7021 ttatcgatgt ttacttgatg ggtaaactga tagattagta gaaatatggt taaaaaaatt
     7081 attggaatgg tgctagcttt actttctgta actgtagtag gagtaggtgt ttttgcttat
     7141 actatttatc aacaagggac agaaacctta gctaaaacct ataaaaaaat cggcgaagaa
     7201 accaaggtta ttgaagcgac tgaacctcta accattctgt taatgggagt ggacaccgga
     7261 aatgctgaac gaactgaaac ttgggtcggt agaagtgata gcatgatctt gatgacagtg
     7321 aatcctaaaa cgaaaaaaac aacaatgatg agtttagagc gggatattct gacgcgcatt
     7381 gaatcaggga atggtcaggc tcatgaagcg aaactgaact cagcatatgc agatggtgga
     7441 gcagagcttg ctatagaaac cattcaaaaa atgatgaata tccatattga tcgctatgtg
     7501 atggtcaata tgagagggtt gcaaaaacta gtggatgcag taggaggtat tacagtcaat
     7561 aatatcctag gtttcccaat ttctatcagt gaccaagaag aatttaatac tatttctatc
     7621 ggtgttgggg agcaacatat tgggggagaa gaagccctag tctatgcacg aatgcgttac
     7681 caagatcctg agggggatta tggtcgtcaa aaacgtcaac gtgaagttat tcaaaaagtc
     7741 atggaaaaag ctctcagttt aaatagcgtt ggtcattatc aagagattct aaaagctttg
     7801 agtgacaata tgcagaccaa tattgatttg tctgcaaaaa gtatccctaa cttgctaggc
     7861 tataaagatt catttaaaac cattgaaact cagcagttgc agggtgaagg agagatactt
     7921 caaggtgttt cttaccagat tgtttcgaga gcacatatgt tggaaatgca aaatatactc
     7981 cgacgttctt tgggacaaga agaagttact cagcttgaaa ccaatgcggt tttatttgaa
     8041 gatttatttg gcagagcacc tgttggtgat gaagataatt aacttttgat acaaataaaa
     8101 aaatcaatcg taggaaaatt cctgcgattt tttcaaaaaa atacgaatag ataggtagga
     8161 ggaaacatga aagcagaaat cattgctgtt ggaacagaga ttttgacagg acagattgtc
     8221 aacaccaatg cccagttttt gtcggaaaaa ctagctgaga ttggggtaga tgtatatttt
     8281 cagacggctg taggagacaa tgaagttcgt ctcttgtctt tgcttgagat tgccagtcaa
     8341 cgtagcagtc tggtgatttt gacaggcggt ttggggccaa ctgaggacga cctaaccaaa
     8401 caaaccctag ctaaattttt agggaaagca ttagtctttg atcctcaggc tcaggagaag
     8461 ttggatatct tttttgccct gcgaccagac tatgcccgaa caccgaataa cgaaagacaa
     8521 gctcaaattg tagaaggagc gattccactg ccaaacgaaa caggactggc tgttggagga
     8581 aaattagaag tagacggagt gacctatgtc gtccttccag gtccgccaag tgaattgaaa
     8641 cccatggtct taaaccaact tctacccaag ttgatgacag ggagcaagct gtattcccga
     8701 gttcttcgtt tctttgggat tggcgagagc cagttggtta cgattttggc tgatttaatt
     8761 gataatcaga tcgatcctac cttggcccct tatgccaaga caggagaagt cactctacgt
     8821 ctgtcaacaa aggctagcag tcaagaagag gcgaatcaag cgctggatat cttggaaaat
     8881 caaatcttgg actgccagac tttcgaagga atttctttac gagacttttg ctatggttat
     8941 ggggaagaaa ctagtttagc cagcattgtg gtagaagaac tgaaaaggca agggaaaacc
     9001 atcgcggctg cagagagttt aacggcaggt cttttccaag ctaccgtggc gaatttttct
     9061 ggagcttcaa gtatatttaa gggtggtttt gtgacctata gcttggagga aaaatcaagg
     9121 atgttggata ttcctgccaa gaatttggaa gaacatggtg tggtgtctga atttacagct
     9181 cagaagatgg ctgagcaggc acgaagcaag acccagtctg attttggaat tagtttgacc
     9241 ggagtggcag gaccagatag cctagaagga cacccagttg ggacagtctt cataggcttg
     9301 gcgcaagagc aaggaactga ggttatcaag gttaatattg gaggcagaag ccgagcagat
     9361 gtacgtcata ttgcggttat gcatgccttt aacctagttc gcaaggcttt attaagtgac
     9421 taacttttga tataatagta gataggtctg aggatcatta gaatgtagga gaatagaatg
     9481 gcgaaaaaac caaaaaaatt agaagaaatt tcaaaaaaat ttggggcaga acgtgaaaag
     9541 gccttgaatg atgctcttaa attgattgag aaagactttg gtaaaggatc aatcatgcgt
     9601 ttgggtgaac gtgcggagca aaaggtgcaa gtgatgagct caggttcttt agctcttgac
     9661 attgcccttg gctcaggtgg ttatcctaag ggacgtatca tcgaaatcta tggcccagag
     9721 tcatctggta agacaacggt tgcccttcat gcagttgcac aagcgcaaaa agaaggtggg
     9781 attgctgcct ttatcgatgc ggaacatgcc cttgatccag cttatgctgc ggcccttggt
     9841 gtcaatattg acgaattact cttgtctcaa ccagactcag gagagcaagg tcttgagatt
     9901 gcgggaaaat tgattgactc aggtgcagtt gatcttgtcg tagtcgactc agttgctgcc
     9961 cttgttcctc gtgcggaaat tgatggagat atcggagata gccatgttgg tttgcaggct
    10021 cgtatgatga gccaggccat gcgtaaactt ggcgcctcta tcaataaaac caaaacaatt
    10081 gccattttta tcaaccaatt gcgtgaaaaa gttggagtga tgtttggaaa tccagaaaca
    10141 acaccgggcg gacgtgcttt gaaattctat gcttcagtcc gcttggatgt tcgtggtaat
    10201 acacaaatta agggaactgg tgaccaaaaa gaaaccaatg tcggtaaaga aactaagatt
    10261 aaggttgtaa aaaataaggt agctccaccg tttaaggaag ccgtagttga aattatgtac
    10321 ggagaaggaa tttctaagac tggtgagctt ttgaagattg caagcgattt ggatattatc
    10381 aaaaaagcag gggcttggta ttcttacaaa gatgaaaaaa ttgggcaagg ttctgagaat
    10441 gctaagaaat acttggcaga gcacccagaa atctttgatg aaattgataa gcaagtccgt
    10501 tctaaatttg gcttgattga tggagaagaa gtttcagaac aagatactga aaacaaaaaa
    10561 gatgagccaa agaaagaaga agcagtgaat gaagaagtta cgcttgactt aggcgatgaa
    10621 cttgaaatcg aaattgaaga ataagctgtt aaagcagtgg agaaatccgc tactttttcg
    10681 atttttgatt caagttttta gattatatat agtagcttga aataagatat gaacaactct
    10741 attaggaaag tcaaattaat ttctagaaat gttttagcag ctacagcgta ctattccaaa
    10801 ctcaaccaac tataatagat cgaaactaga atagtacata tctacttcta aaacattgtt
    10861 aaaaatcgat ttgactttcc ttatttcatt ccgctatata taagtttgct gtttcttgtc
    10921 gctcctctgg aaagctgata taatagcttt atgaataaaa aacgaacagt ggacctgata
    10981 catggtccga ttcttccctc gctcttaagc ttcacctttc caattttgct atcaaatatt
    11041 tttcaacagc tctataacac tgctgatgtc ttgattgttg gacgatttct tggtcaagaa
    11101 tccttggctg cagtaggagc gacgacagcg atttttgacc tgattgtagg ttttacactt
    11161 ggtgttggca atggcatggg gattgtcatt gctcgttatt atggggctcg gaatttcact
    11221 aaaatcaagg aagcagtagc agctacttgg attttaggtg ctcttttgag cattctagtt
    11281 atgttgctgg gctttcttgg cttgtatcct ctcttgcaat acttagatac tcctgcagaa
    11341 attcttcctc aatcttatca atatatttct atgattgtga cctgtgtagg tgtcagcttt
    11401 gcttataatc tttttgcagg cttgttgcgg tctattggtg acagtctagc agccctggga
    11461 tttctgattt tctctgcctt ggttaatgtg gttctggatc tctattttat tacgcaattg
    11521 catctgggag ttcaatccgc aggacttgct accattattt cgcaaggttt atcagcggtt
    11581 ctctgctttt attatattcg taaaagtgtg ccagaactct tgccacagtt taaacatttc
    11641 aaatgggaca aaagcttgta cgcagatctc ttggagcaag gtttggctat gggcttgatg
    11701 agttcaattg tatctatcgg cagtgtgatt ttacagtctt ctgttaatac atttggtgca
    11761 gtgattatta gtgcccagac ggcagctcga cgcattatga cctttgccct tcttcctatg
    11821 accgctattt ctgcatcaat gacgaccttt gcttctcaga atctaggagc taagcaacct
    11881 gaccgcattg ttcaaggtct tcgaatcggc agtcgtttaa gtatatcctg ggcagttttt
    11941 gtttgtattt tcctcttttt tgccagtcca gccttggttt ccttcttggc tagttcgaca
    12001 gatggttact tgatagaaaa tggaagtctc tatctgcaaa tcagttcagc cttttatccc
    12061 attttgagcc tcttgttgat ttatcgcaat tgcttgcagg gcttggggca gaagatcctt
    12121 cctctagttt ctagctttat tgaactaatc ggaaaaatcg tttttgtggt tttgattatt
    12181 ccttgggcag gatataaggg tgttatcctt tgtgaacctc ttatctgggt tgccatgaca
    12241 gttcaactgt acttctcact attccgtcat cccttgataa aagaaggaaa ggcaattttg
    12301 gcaaccaaag tgcaatccta gttggattta ctgaataaaa tccatttcct ctagtgaaaa
    12361 tcgaaaaaac ttgtgttctc ttctttagtt tggtgttgaa aatagtttaa cagacttttg
    12421 acttctttta tatgatataa taaagtatag tatttatgaa aaggacatat agagactgta
    12481 aaaatatact tttgaaaagc tttttagttt ggggtgttat tgtagataga atgcagacct
    12541 tgtcagtcct atttacagtg tcaaaatagt gcgttttgaa gttctatcta caagcctaat
    12601 cgtgactaaa attgtcttct ttgtaaggta gaaataaagg agtttctggt tctggattgt
    12661 aaaaaatgag ttgttttaat tgataaggag tagaatatgg aaattaatgt gagtaaatta
    12721 agaacagatt tgcctcaagt cggcgtgcaa ccatataggc aagtacacgc acactcaact
    12781 gggaatccgc attcaaccgt acagaatgaa gcggattatc actggcggaa agacccagaa
    12841 ttaggttttt tctcgcacat tgttgggaac ggttgcatca tgcaggtagg acctgttgat
    12901 aatggtgcct gggacgttgg gggcggttgg aatgctgaga cctatgcagc ggttgaactg
    12961 attgaaagcc attcaactaa agaagagttc atgacggact accgccttta tatcgaactc
    13021 ttacgcaatc tagcagatga agcaggtttg ccgaaaacgc ttgatacagg gagtttagct
    13081 ggaattaaaa cgcacgagta ttgcacgaat aaccaaccaa acaaccactc agaccatgtg
    13141 gatccatacc cttacttggc aaaatggggc attagccgtg agcagtttaa gcatgatatt
    13201 gagaacggct tgacgattga aacaggctgg cagaagaatg acactggcta ctggtacgta
    13261 cactcagacg gctcttatcc aaaagacaag tttgagaaaa tcaatggcac ttggtactac
    13321 tttgacagtt caggctatat gcttgcagac cgctggagga agcacacaga cggcaactgg
    13381 tactggttcg acaactcagg cgaaatggct acaggctgga agaaaatcgc tgataagtgg
    13441 tactatttca acgaagaagg tgccatgaag acaggctggg tcaagtacaa ggacacttgg
    13501 tactacttag acgctaaaga aggcgccatg gtatcaaatg cctttatcca gtcagcggac
    13561 ggaacaggct ggtactacct caaaccagac ggaacactgg cagacaagcc agaattcaca
    13621 gtagagccag atggcttgat tacagtaaaa taataatgga atgtctttca aatcagaaca
    13681 gcgcatatta ttaggtcttg aaaaagctta atagtatgcg tttttatcct ctagtcactt
    13741 gatttgtttc aggtggtttt ttagtatagt agaatgaaac gagaacagga caaattgatc
    13801 aggacagtca aatcgatttc taacaatgtt ttagaagcag aagtgtacta ttctagtttc
    13861 aatctactat agttaaatct gcggtcaagt ctactggtga atctatgatt gtaatactct
    13921 tccaaaatct catcaaccac gtcagtcttg ccttgcagtc tgtatcttac tgaccaagct
    13981 agtgatggat ttagaatagg tgatttggag cgtcctattg gctaggaaat gctgctcata
    14041 gtcctttgct gaggctaggg tgtttcaaca ttcaacactc aactggttga tctagttgat
    14101 aggaagggaa ttactataaa atactcaggc ttccatcata ttttttgaaa cgattgtgta
    14161 atcaaaatgt accaatattg tagtattggt acagaagatg ttgtgaatgg ataaatatat
    14221 cataactgct gtctcaaaaa gatttcatat gtctgtgcat atataataga cttcctgcga
    14281 aaccaaaatc ctagttcatg attgataata ccagcactca aattcattcg taatccgaag
    14341 cgtttacgat gatttcgata ggttgttgaa atcattttaa acgtttttac tttggcaaag
    14401 atgttctcaa ccttgcttct ctccttggat agcgcatggt tacaggcttt atcttcaact
    14461 gttagtggct tgagtttgct ggatttacgt ggagtttgtg cttgaggata tatcttcatg
    14521 agcccttgat aaccactgtc agccaagatt ttaccagctt gtccgatatt tccgcgactc
    14581 attttgaaca acttcatatc atgacaatag ttcacagtga tatccaaaga aataattctt
    14641 ccttgacttg tgacaatcgc ttgagccttc atagcgtagc atttcttttt accagaatca
    14701 ttcgctaatt gtttttttag ggcgattgat ttgtacttcc gtcgcatcaa tcattaccgt
    14761 gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa gagttacttc
    14821 aacccattgg ctccgacgga ttaagttgct ttcgtgaata ccaaaatcag ccgcaa
//
LOCUS       DBEJZV010000047        13682 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.47, whole genome shotgun sequence.
ACCESSION   DBEJZV010000047 DBEJZV010000000
VERSION     DBEJZV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13682
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.47"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            70..1329
                     /locus_tag="ACL3S0_001885"
     CDS             70..1329
                     /locus_tag="ACL3S0_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGR1312748.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1405..1540
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1579..2079
                     /gene="rplJ"
                     /locus_tag="ACL3S0_001886"
     CDS             1579..2079
                     /gene="rplJ"
                     /locus_tag="ACL3S0_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGR1312749.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2155..2523
                     /gene="rplL"
                     /locus_tag="ACL3S0_001887"
     CDS             2155..2523
                     /gene="rplL"
                     /locus_tag="ACL3S0_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGR1312750.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2710..2883
                     /locus_tag="ACL3S0_001888"
     CDS             2710..2883
                     /locus_tag="ACL3S0_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312751.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQS"
     gene            2880..3128
                     /locus_tag="ACL3S0_001889"
                     /pseudo
     CDS             2880..3128
                     /locus_tag="ACL3S0_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3142..3465
                     /locus_tag="ACL3S0_001890"
     CDS             3142..3465
                     /locus_tag="ACL3S0_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312752.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKQPINFANLLDSLIVSEYQMEPNLW
                     EVSHD"
     gene            3458..3838
                     /locus_tag="ACL3S0_001891"
     CDS             3458..3838
                     /locus_tag="ACL3S0_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR1312753.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3851..4045
                     /locus_tag="ACL3S0_001892"
     CDS             3851..4045
                     /locus_tag="ACL3S0_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGR1312754.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIV"
     gene            4087..4674
                     /locus_tag="ACL3S0_001893"
     CDS             4087..4674
                     /locus_tag="ACL3S0_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR1312755.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYCASLIS
                     FLWMYAQRKQAHKVNMKSRIKWIGIGLASLLIISLCFSLIHAQESTNQANLIGLQYQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            4876..5013
                     /locus_tag="ACL3S0_001894"
     CDS             4876..5013
                     /locus_tag="ACL3S0_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR1312756.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5192..7801
                     /locus_tag="ACL3S0_001895"
     CDS             5192..7801
                     /locus_tag="ACL3S0_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR1312757.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSERLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGGIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            7834..9774
                     /locus_tag="ACL3S0_001896"
     CDS             7834..9774
                     /locus_tag="ACL3S0_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HGR1312758.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            9771..11378
                     /locus_tag="ACL3S0_001897"
     CDS             9771..11378
                     /locus_tag="ACL3S0_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1312759.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            11393..12133
                     /locus_tag="ACL3S0_001898"
     CDS             11393..12133
                     /locus_tag="ACL3S0_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312760.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            12136..13455
                     /locus_tag="ACL3S0_001899"
     CDS             12136..13455
                     /locus_tag="ACL3S0_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR1312761.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYCKSY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            13588..>13682
                     /locus_tag="ACL3S0_001900"
     CDS             13588..>13682
                     /locus_tag="ACL3S0_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR1312762.1"
                     /translation="MAAEVLNLQLVSVQVDETDEVDGMRFSTFST"
BASE COUNT         4593 a         1913 c         2689 g         4487 t
ORIGIN      
        1 acctacggca aagtgaatct gaagtggttt gaagagagta caacttgtct tttaaaaaag
       61 gagtctataa tgaaagtctt tcagcatgta aatatcgtga cttgtgatca aaatttccat
      121 gtttatcttg atggaatctt agcagtcaag gattctcaaa tcgtctatgt cggtcaagat
      181 aagccagcgt ttttagaaca agctgagcag attatagact atcagggagc ttggattatg
      241 cctggtttgg tcaattgtca cacccattct gcaatgacag gtctgagagg gatccgagat
      301 gacagcaatc tccatgaatg gctcaatgac tatatctggc cagcagaatc tgagtttact
      361 cccgacatga ctaccaatgc ggtcaaagaa gccctgacag agatgctcca gtcaggaaca
      421 acaaccttta acgatatgta taatcccaat ggtgtggata tccagcaaat ttatcaggtg
      481 gtgaaaactt ccaagatgcg ttgttatttt tctccgactc tcttttcttc agagacagaa
      541 acaactgctg agactataag cagaactcga tccatcatag acgaaatctt aaaatataaa
      601 aatccaaatt tcaaggttat ggtagcacct cattctccgt atagctgcag tagagacttg
      661 ctggaagcga gtttggaaat ggcaaaagag ctaaatattc cgctccatgt ccatgtggcg
      721 gagaccaagg aggagtcagg aattatcctc aaacgatacg gcaaacgccc ccttgctttt
      781 cttgaagaac tgggttattt agatcatccg tccgtatttg ctcacggggt cgaattaaac
      841 gagagagaaa ttgaacgctt ggcatcttct caagtggcta tcgcccacaa tcctatcagt
      901 aacctcaaac tggcatcagg aattgctcca attatccagc tccaaaaagc gggagtagca
      961 gtcggaattg cgactgactc ggttgcttcc aataacaatc tagatatgtt tgaggaagga
     1021 aggactgcag ctcttcttca gaagatgaaa agtggggatg ccagccagtt tccaatcgaa
     1081 acagctctca aggtactgac aatcgaaggg gctaaggtcc ttggaatgga aaatcagata
     1141 ggaagtctgg aagtcggcaa gcaagcagat tttctggtca ttcaaccaca agggaaaatt
     1201 catctccaac ctcaggaaaa tatgctgtct cacctggttt atgcagttaa atctagtgat
     1261 gtagatgatg tttatatcgc cggagaacag gttgttaagc aaggtcaagt cctgacagta
     1321 gaactttaaa agaaaaatca cgaaaaattt taaaaaaagt ttgcaaaaat cttgcattct
     1381 ttttttgact atgctatact tatatacggt ttaaaaaaac tgcctaagac agtaggggag
     1441 ctcgactcat aaatatccta ccgaggacaa gacgtatcat gtaaaaagaa gcgtattgta
     1501 ctttcgtgtc taggtttggg cgcgtttttc tttttgaaaa attccccaag caaaataatt
     1561 acggaggtga acacactaat gagtgaagca attattgcta aaaaagcgga actagttgac
     1621 gtagtagctg aaaaaatgaa agctgctgca tctatcgtcg ttgtagacgc tcgtggtttg
     1681 acagttgagc aagatacagt tcttcgtcgt gagcttcgtg gaagcgaagt tgagtataaa
     1741 gttattaaaa actcaatctt gcgtcgtgca gctgaaaaag ctggtcttga agatcttgca
     1801 tctgtatttg ttggaccatc tgcagtagca ttttctaatg aagatgttat cgcaccagcg
     1861 aaaatcttga acgacttttc taaaaacgct gaagcacttg aaattaaagg tggtgcaatc
     1921 gaaggcgctg tcgcatctaa agaagagatt cttgcacttg caactcttcc aaaccgcgaa
     1981 ggacttcttt ctatgctcct ttctgtactt caagcgccag tgcgcaacgt tgctcttgca
     2041 gtcaaagcgg ttgcagaaag caaagaagac gcggcttaat cttaagctac acagcgtagc
     2101 ctagctacga aaaaaactat tataaaattt aaaacttatt tggaggaaat aacaatggca
     2161 ttgaacattg aaaacattat tgctgaaatt aaagaagctt caatccttga attgaacgac
     2221 cttgtaaaag ctatcgaaga agaatttggt gtaactgcag ctgctcctgt agctgttgct
     2281 gcagctgatg cagctgatgc tggtgctgct aaagattcat tcgacgttga attgacatct
     2341 gcaggcgaca aaaaagttgg cgttatcaaa gttgtacgtg aaatcactgg tcttggtctt
     2401 aaagaagcta aagaacttgt tgacggtgca ccagcacttg ttaaagaagg cgttgcaact
     2461 gcagaagctg aagaaatcaa agctaaattg gaagaagctg gagcttcagt tactcttaaa
     2521 taatagagta tcgcaatttg attgcggaat ccctatttac cagtctttga gagcgataag
     2581 cgattgatag aaactgataa attgatttgc tttcctgcca aaaattcttt ggcaggattt
     2641 ttgttttaat aaactttcgg gggtagacac tagattgtct accccttttt ttgtgtttcg
     2701 gaggtaatta tgcaaaagga aggacagtca tcacgtcaat tcgtgaagag tcatctcatg
     2761 actatcatgg gagttgatat tgtaaaagca actcagttag ttgatgaaat ggaacaagta
     2821 ggtttaatcc gatttgatga atttggaaat gttggaattt tagtcttgga gggacaatca
     2881 tgaagcgtat taccgctagt caatatcaga catcagagcg ttattataag ctccccaaac
     2941 ttttatttga gagtgaacgg tataagaata tgaaactgga ggttaaggtg gtttactcag
     3001 ttttaaaaga tcggttggag ttgtctttga gcaaaggttg gattgatgag gatggggcta
     3061 tttatttgat ttattccaat tcaaatttga tggcactttt aggctgttca aagtcaaaat
     3121 tactctccat gtgagtttga agtgacattt ttagatgatt accataaaaa acataactac
     3181 ccactatttt acgaatccta tcttcaaaac attatggaat tccttgaaag tcaggatata
     3241 aagaacggag ctgatgcctt tgtagatgat catcaaaatc ttgtttttgt tttatatgga
     3301 caaggctatc gagccgaggg aaaagaggga atacttacaa cccaagtaac tgtaaaagct
     3361 tatgatgaag acaagcaacc gattaacttc gcaaatttat tagattcctt aatcgtctca
     3421 gagtatcaaa tggaaccgaa tctttgggag gtctcccatg attgatctct atctaagtaa
     3481 aaatagccaa agaaatcaac ttcttttaga cttcttccaa aactatggca tcgaggtatc
     3541 ttgtcattca gtttctgaaa tgacaaagga taaattaatt gagatgatga gctattcttc
     3601 agattgtttt gagtttttat ctcccaattt attacgattt aagaaccgtg acaatttaag
     3661 attaacggat ttcattgaaa tgatattaaa aaatcctgaa ctaaccatca gacttcctct
     3721 tgcagtttca aataagagag tttatccaaa tctaaatttg gaggaagcta gagctttatt
     3781 gccaagagat acgaaacaat tgatttacat ggcgcaaaca cattatttat ctaactaaag
     3841 gagaagcaat atggctgaac gattttggga gaacttgtcc attattttgg ctgaaagaaa
     3901 tatcagctgg attgagctaa ccagaaaaat gtttgcggga gagtttcact atccaagtga
     3961 attgaatcgt ttgtatcaaa agattcgtca ctacaagatg gaacaacgaa tgcctcaaag
     4021 tccatgggta gaaaggattg tgtaggtatt agatttagat tatgaagatt tatttcggag
     4081 gtaactatga aaagaataat tccagtttat atattccaac aagtaaatgt cctattggta
     4141 tctctatact tactgaaatt tctttgtatc ggtgagttaa ctatactaca gattctatat
     4201 tgtgcgtcac tcatttcttt tttatggatg tatgcccaac gtaaacaagc gcataaggtc
     4261 aatatgaaat caaggataaa atggattggt attggattag ccagtctact gattataagt
     4321 ctatgtttta gtctaatcca tgcgcaagaa agcacgaatc aagcaaactt aattgggctt
     4381 caatatcaag ttccttggtt ttcattttta ttgttcttaa tcaatgcgag tatggttgaa
     4441 gaatttctgt atagagaaat tttatggaac ttggttagaa aattagatat tcgagttgct
     4501 ttgacaagtg ttttatttgc cttagcacat catccaggaa ccattatagc ttggtgtttg
     4561 tatgtatcgc tggggatgtt tttagggctt gtacgctaca aattggactt atggggcagt
     4621 atggggttac atttggtgtg gaacctacta gtttatagtt tgctgctttt ttaaaatagg
     4681 taacctgatt tttaggtaac ttctaaaact aacttccagt tttgggagag agatggaagt
     4741 tactttgaaa agttacggaa acattatttt ctatgtgaca acattgtata attgcttgca
     4801 ttttactggt ggagagagta taatgagggt ggataaagta cttaatccca aaaatttaaa
     4861 taggaggagc tagctatggc agaagaagta ttaaatcttc aattagtatc tgttcaagtt
     4921 gacgaaacag atgaagttga tggaatgcga tttagtacat tcagtacaaa tcgttgcggt
     4981 aactggagtg cttttagttg ggaaaattgt taattcattt aaattgtaaa ctttagagat
     5041 tctctggagt tatggatgtc gttccaatat gtgcacgttg gaatgttagt gcttatatgg
     5101 ggagaatcca aaggattctc cctttttatt taaataagtc tgtctagcta tagatatatt
     5161 aagtttgata aaatttcttg gagattttgt tatggattat aatttcaatt tggagcatcc
     5221 tttctttttc actaataatg attatagtac agatactagc ataaagtacc aagtaagtct
     5281 gccttttaat tggcacgaag taatgaataa tgatgagtgg gtttatcaat accctattgg
     5341 aaaatttgtt gaaagacaag ggtggaaaat acacattagt tcagagtata acagttcaca
     5401 tgaattgtta caagatgtag caaaaatttg ccatgaaatg cgaattccat ttaaacatct
     5461 tagtacagaa gacaaattta tcatgcgaaa cgggaaattg gttagtcgag gattttctgg
     5521 taaatttatt acatgttatc caaatcaaaa tgaattagag tcggttttgc aaaggttaga
     5581 aagtgcttta aagcaatata atgggccata tattttaagc gataaacgtt gggatgaagc
     5641 accaatatat ctgaggtatg gtgtgtttag gccgtcaagg gatgatgaaa agaaggttgc
     5701 tattgatgaa ttaattgttg gcgatgaagt tgttaaagat gaacgtttac cagtatttaa
     5761 aattccaaaa ggtatagtgc cccctgactt tttgaataaa tggcttgaca agaaagataa
     5821 aaaacaggga gactttccct ttattataga taatgcaatt agattttcaa acagtggtgg
     5881 gatatataat gctaggctaa aagaagatgg gaaaaaaata attttaaaag aggctagacc
     5941 gtatacaggt ctaggatttg atggtactta ttcttcagag agattagctt cggagtgcaa
     6001 agcactaaaa attctaaatg aatggagtga gacgcctaaa atatactggc acggtaagat
     6061 ctgggagcac accttcttag gaattgaaca tatgaagggc gttccactaa atagatgggt
     6121 taccaataat tttcctttat atgaagttgt tgataagacc aaagattatc tattgagagt
     6181 ttcaaagata gtagaaaaac tcatcgattt aacgaataag tttcattctg aaaatgtata
     6241 tcatcaagat ttacatttag gaaatatctt ggttaaggat gaagatgaga ttagtataat
     6301 agactgggaa caggctgtct tttcaaatga tgaaaaagtt gtacataaag ttgcagcccc
     6361 tggttttaga gcatggcgag aaacacttcc cagtgagata gattggtatg gtattagaca
     6421 aatagctcat tatttataca tgccactagt aactacatcg gatttgacat acaactatgt
     6481 aagtcaaacc aggatagaag gaaaaaaact atttgagtct ttgggttata caagagaaca
     6541 tatagattat gtagaaagtt tattgtcata tctagattct aaatgtccac agattgagaa
     6601 tatttccagg aaaaaagttt taaaacccat gcatgagatt agaactatcg agagtgagca
     6661 agatatacaa gattttatta taaaattatt gagagggttt acgctaactt atggacagtg
     6721 gcgtaaagaa tttcaatcaa gattcttccc agttcattat tatggtctga attttaatca
     6781 aggaattgcg ttttcagatt tagctatcct ttggagttat caacaactag ctaagaaagt
     6841 aaaaaatttc aagtttgatg actattatga gattcgaaca caggttatta atgaggcagt
     6901 aaataatttt aagaaatcgt ccctttctgg tctttttgat ggtaaaattg gtacaatctg
     6961 gctcatttat gaatttgggg agatagatcg ggcagttgaa ctttttacaa ctcattttat
     7021 agagatattt gagaattcac aaaataaaaa tttatatagt gggcaggctg gaattttact
     7081 ggttggactg tattttctta gtaaaggggg aattgataat aaactaggag aagaaatact
     7141 aattaggctt agagaatata ctttaaatta tatagaaaat ccagaaactt tttgtaaagt
     7201 tggcgctagt gatgttcaga gtaacgatcc ttatgagaat tttggtggat tactatatgg
     7261 tcacgcaggg gtagcttggc tcttcggtga agcttataaa ttaactggtg aaagtatcta
     7321 taaaaatggt ctagaattgg ctgtagataa agaattagtt gcttataaag tagatagtaa
     7381 taattcattg cagtacagcc aaggtcatag attactacca tatctagcaa ctggaagtgc
     7441 tggcctgctt ttacttatta atagaaataa agaaatcttg tcaagcaaat acttaaaata
     7501 tttaacttct ttagagaggg caactgatgt agttttttgt gtattaccag gtttatttaa
     7561 cggattttgt ggtcttgaag ttgctaataa tatatatagt gatatcgatg ataacttttc
     7621 aggacaaaag aaattaattg aacaacttta tagatatttg tgtgtaattg aagaaggatt
     7681 tgttattgcg ggagataatg gtttaaagat aacaacagat attgcttcgg gatttgcggg
     7741 tgttgcaatt ggattggtat caataatgga taataaattg acgattcttc ctcaaatata
     7801 atatttagat accattatta aggggtcata cttgtgaatc agagtaatga aatattttta
     7861 aatacaatac aggaaaaaac acactataag aggtctatct cttcatcatt tcaggaatta
     7921 aaaaaatgga attctttgat atttaggaga gggcgatatt ggtaccaatt tgataattgg
     7981 agtataccca atactggtgt aataaaggaa tggtatgtcg aagataatga ctggattcct
     8041 aaggttagtt cttccagttt agacaattca aattcactta aaattgtctt tgatgtggaa
     8101 aaatatactt tgccagatga tagtatctta caggatgtta ggatttcatc tgatgagagt
     8161 tatatagttt tggttgtatc ctcactgcgt agcactaatt taattggaat aaaaaaatat
     8221 actatggaag agttatttat cattgaagat atttcagtag aaagttcgtt ctatttgggt
     8281 aaattcggtg ttatgtatac tcgctccaaa gagtacggga ggccaagtaa gttattctat
     8341 aaatcttttg atagctttac agaagaggaa ctgtttgaag aaaacgaatg ctcttttcga
     8401 ttaaaaatag tccacattga tagcaataat tgttttgtaa agtcagtaga ctttcagaaa
     8461 ggcaggattt ttctatacag tttcgaccgg acgggttttg ttagacactc ttacacagaa
     8521 acggtagccc caacacctag agatatcgct ctatttagta cagaaaaagc acagtacttt
     8581 cttgggctct cttcaactga agaaaagaaa gatcaactaa ttctaaggga aacttcttcg
     8641 ggagacagag tttctattac tataccatat caagataggg ctagaagagt tcactgtata
     8701 ggacgttata tccttttaga ctgttcaaac gcagcgaatt ccgtctttta tcttgctaca
     8761 tttaaaaata atagtttgag ggagttgagt gttaataaga taacatttga tgaaaagaca
     8821 acactttatg aaaattcatt ttctgatcgt gttcttctgt ttttagagag gagaactttt
     8881 tacgaaaaaa tacttagttt tgatttaata gaaaatacat taaaaactga atttgaaaga
     8941 cccatcataa aatcgaataa tactaaatat ttttctaagg tgatttggac taaaaaagac
     9001 agttatgatg taagcatacc gatttcttta ttttggaaaa gtgaagatac ggatgagctc
     9061 ccaagaagaa aaaaatgtat tctaagtgtc tatggggctt atggtaagaa tgataattct
     9121 gatttagatg aaattatgtt atctataata gatgcaggtt ttatttatgc tatagttcat
     9181 gtaagaggtg gaggctattt gggtggtgaa tggtatcgct caggaaaggc gttaaacaaa
     9241 tggaattcta tcagagattt tattgaggga gtaaattatt taagggaaaa tgatgtaatt
     9301 gacagtaagc gattaggttt aataacttct agtgcaggtg gaataattgc tggtgcggtg
     9361 ttgaacgagg aaaaaaattt attgcaaagc attctcttat tttcgccatt tataaatcct
     9421 tatgatacac ttcagaatcc aaatgatcct ctttctaaga ccgaaatagc agagtgggga
     9481 gatattagag accctgaagt aaaggcttat ataaagtcat attcgcctat gcaaaatatt
     9541 gaaaaggcac gagactcaaa tactgttata gttaatattt tgggtgagaa agacccatat
     9601 attaataata acgaagtgat agagtggtca aagaaattaa attctattgg agttaaaagt
     9661 ttgttgtatt taaacaaagc agctggtcat ggaggtttta ctccatcaga tgttctctta
     9721 atgattgata ctttaaatta tttctttgaa gaagtgggaa ggaataactt atgaattatt
     9781 taaaatttat aaaaaagact aaacttatat taatggggat tttaatattt ctatcttcgt
     9841 ttaatggtgt cttgctctca ggaattattg tatatgcagg tagtttaaat cagacttcct
     9901 cattttctga cgttctaaga tttggtgcta taagtattct gggttggtca gcaatctata
     9961 tatcaaatta ctatttagaa gtaacggaag catcaataac taaagatata aatgtaaaaa
    10021 ttaaacaagg atattttaga gaacagtatc tttcttctga aatggttaaa gattactcat
    10081 ctattatttc agttttgtca aatgatttga gattaatcga agaaaactat tttagacaaa
    10141 tttttgaaat aatttcttca atattgttgt tcatcgtctc tctaagtttt atgctttatt
    10201 taaacttcct agtttcaata atatttattg tattatcagc attgccgatt atagtacctg
    10261 tctttatgaa gaagatgttg tctaattcag ctaatgagta ctctaacagc aatgcagagt
    10321 atactcacat aataaaagaa atttttaatg gttttaagac attaaaatct tattctgtta
    10381 ctaaagaaat aattagtttg tcggataaaa agttggataa actagaagat tctactttta
    10441 atttgaaacg atcagaggtt ctttcaaaat tggttgcagt actaatttca ggtttttgct
    10501 ttctagttcc cttggttgta ggatgttatt ttgtaattta tcataaaagc ctttctttta
    10561 gtgaactgat aggtattttc ttagcaaacg ataaagtttt agggccgata caatcaattg
    10621 cctattcatt aaataagata aatacaacca aagatttaag gaaaccgttt ttaaaatact
    10681 taagtggaga gaagaatttt atagacgctg aacatgataa taacggactg tatacttcat
    10741 caatagatga gatacacatg aaagatgttg tatattctat tacaccagaa aataaattaa
    10801 gtattgactt ctcatttaag tcaccattta gggtattatt aacaggaact tctggtagtg
    10861 ggaaaacaac gattttaaat ttaattaatg gttctttaaa gccacaaaaa ggttatgtaa
    10921 atttgttatc acatgggaaa aagagttcag attcaatacc aacagttgat cagacaccat
    10981 atatttttga cactactatt cgtgagaacg taactttatt tcaaaatgaa tatttttcag
    11041 atgatcagat aattgaggtg ttaaaaaagg taaatctata tgaagaatta gaaaagatag
    11101 atatactaaa ttatcaatgt ggtgaaaatg gtagtaattt gtctggaggt caaaaacaaa
    11161 aaatagcttt agctagagct ctgattagaa ataataaagt gtacttattt gacgaaatat
    11221 cagctaattt agataatgat aattcaaatt ccatacatga tattctgttc aatttaggta
    11281 tttcatttat tgaagtttca catcattatg acttaaatga caagagatac actgatatat
    11341 ataaattgga aaatggaaca cttttcaaaa ttaagtgatt ggaggcaaga atatggataa
    11401 agattatata ttaaaagtga aagggctgta tcatcaattt ttactaggaa ataataaaac
    11461 gttgcaagtg ctgaaaaatg tttctctttc tgcttcgaga ggagaattta taagtattct
    11521 aggaattagt ggttctggaa agtcaacttt attaaaatgt atttctagtt tgcttgaacc
    11581 aacaagtggg gaagtaattt taaatggaat caacccctat aaaatcagaa atgcaaaatt
    11641 gtcaagtata agacgtaacg aagtatcttt tatatttcaa gcatacaatt taataccttc
    11701 cctgccggta atagaaaata tagcacttcc tttgcgatta tcacaaaaaa aattaactat
    11761 taaaaatgta gaaaacttac tcaaaagaat gaagtttaat gctggcttaa acgattttgt
    11821 tggaactctg tctggtggag aacaacagaa ggttgctata gctagagcgg ttattgctga
    11881 tagtgatata atatttgctg atgagccaac tggggcttta gacagcgttt ctcgtgaagt
    11941 aatttttgaa ttattgagag agttagtagg ggcgggtaag tgtgtaatta tggtaacgca
    12001 cgatatagaa ttggcctcga aaactgatcg tgcattaata ttgaaagatg gaaaaatttt
    12061 caaagaactt catagaccta gcggggaaga gttgtataaa atcttagagg tacaatcaac
    12121 tacggaggaa tagagatgct cagattagtt tactatcaat ttttacataa taagaaacaa
    12181 tggttaggcg tttcaccagt aatttttgtt tcgagtttag ttatgggatt ggctgttaat
    12241 ggggtaatta atgttgagaa taattcgcaa gtatttgtcg gacttccaga tcctaaacca
    12301 atttttatgt ttccgatagt attcggagga gtaacattat tctttgtgct ctctaacata
    12361 ataaatatgt tggttgaaat ttttagagat gattacgaac ttctggaggt gttgggagca
    12421 agtcgccttc aactatcatt tcttgtgggg ggacagattt ttatcatttc ctcgattatt
    12481 agttttattg catatctatg ctctatattt gttacgtcaa attattatta ttttttacaa
    12541 tactttttcg gggaaaatat attacctgat atccaatttc aaacgagtgc tgttggatgt
    12601 atcattacag tagtgttgat ttcattttta gcctttctaa gtggttgctt ttatacgttc
    12661 aagaagatta gaaataggaa gagttctaaa ataaggcatg ttctttcaat agtaaaaaga
    12721 atactgctat tggctggttt tagtgttatc tggttgcttt ctttgcaaca aattttccaa
    12781 gatagcacaa ttttagcgaa ggcccagata atattcaata ttgtaatctt agatattgtg
    12841 attatttatc aattatctcc ttttatacag tcatgtttta tcaaactact ttctataatt
    12901 atatttagaa ataattttat gttcattgtt tcgaagtgga atttactata ttgtaagtct
    12961 tatataaaat ctatcagtgc tgcaattaca ggagctatat tactaatttc tagttttcaa
    13021 atgatttctc agaatatact atctcaattt caagatgaca gtgatttaga gctaaaagta
    13081 gcatttattg tctatgtagg agcaccaatt ttgatagtac ttgcaaatat tatttcaatt
    13141 gcatttttgt catcgcatca agaaaggatt gagattcagc aatttgaaat tttaggaact
    13201 tctaattacc agatggttaa gattaaagtt ggtgaggcta tatttttgac atttgttact
    13261 tcattaattg catttttact taacattaaa attatggctt taatatacta ctctttagag
    13321 gatattttaa tagatgatat gaatcttttg gggttaatac ttccaaattt tatagtatct
    13381 attattttat ttattttaat atttattact aaaagttcct attttatctt taagaatgca
    13441 aaaattattt cttaaaaatt tgtaagtttt cgctatataa aatagttaaa tctattttgt
    13501 atcattgctt gcattttact ggtggagaga gtatatgagg gtggataaag tacttaatcc
    13561 caaaaattta aataggagga gctagctatg gcagcagaag tattaaatct tcaattagta
    13621 tctgttcaag ttgacgaaac agatgaagtt gatggaatgc gatttagtac attcagtaca
    13681 aa
//
LOCUS       DBEJZV010000048        12676 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.48, whole genome shotgun sequence.
ACCESSION   DBEJZV010000048 DBEJZV010000000
VERSION     DBEJZV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.48"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(294..2021)
                     /gene="ezrA"
                     /locus_tag="ACL3S0_001901"
     CDS             complement(294..2021)
                     /gene="ezrA"
                     /locus_tag="ACL3S0_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGR1312763.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEEKKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPPQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2103..4049)
                     /gene="gyrB"
                     /locus_tag="ACL3S0_001902"
     CDS             complement(2103..4049)
                     /gene="gyrB"
                     /locus_tag="ACL3S0_001902"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGR1312764.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4064..4627)
                     /locus_tag="ACL3S0_001903"
     CDS             complement(4064..4627)
                     /locus_tag="ACL3S0_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR1312765.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4712..5266)
                     /locus_tag="ACL3S0_001904"
     CDS             complement(4712..5266)
                     /locus_tag="ACL3S0_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGR1312766.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5277..6500)
                     /locus_tag="ACL3S0_001905"
     CDS             complement(5277..6500)
                     /locus_tag="ACL3S0_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR1312767.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFCMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6537..8987)
                     /locus_tag="ACL3S0_001906"
     CDS             complement(6537..8987)
                     /locus_tag="ACL3S0_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGR1312768.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVFLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMVIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9187..10116)
                     /locus_tag="ACL3S0_001907"
     CDS             complement(9187..10116)
                     /locus_tag="ACL3S0_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGR1312769.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKIDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQVFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10256..10543
                     /locus_tag="ACL3S0_001908"
     CDS             10256..10543
                     /locus_tag="ACL3S0_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGR1312770.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10577..11911)
                     /gene="ciaH"
                     /locus_tag="ACL3S0_001909"
     CDS             complement(10577..11911)
                     /gene="ciaH"
                     /locus_tag="ACL3S0_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGR1312771.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEINFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(11901..12575)
                     /gene="ciaR"
                     /locus_tag="ACL3S0_001910"
     CDS             complement(11901..12575)
                     /gene="ciaR"
                     /locus_tag="ACL3S0_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGR1312772.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
BASE COUNT         3853 a         2711 c         2249 g         3863 t
ORIGIN      
        1 aagttactca aagtacagat ttgaagctgc agataagact gacgaaatca ctttaatact
       61 aaatgaaaat caaaaagcaa actaagaagc tagcctcagg ctgtacttga gtacggtaag
      121 gcgacgctga cgtgatttga agagattttc gaagagtata aaacactgtt ttgaggtggt
      181 ggataaatcg gctgggtaaa aactcaatct caggagaaaa tgaagtaaat ctccccacaa
      241 ctatagaaaa agatttgatt ctgctcctca cacaataaaa tctttttctt ttattaaaaa
      301 cgaatcgttt cacgtgtttt ctcatatgag gtaacaaagc gattagttac accaggctct
      361 gccacttcca atgcttgaga aatcttgtca aatgaagcgt gataatcaaa ttctttttca
      421 aaaatatcta aagcttcgtt aaatgcttct tgaatgcgtt catcaaatga gcgatagcgg
      481 ttagaatatt gcaagagttg ctctgtcaaa gttgcatatt gtacaatatt ataagtttcc
      541 gtttctaaag cttccatatc attcgttgca atttcaagaa ctcgggtaac agattcaatg
      601 ttaatcattt tttgttctaa ctcaaccatt aaatcctcgg tattattgct tgccgtaaag
      661 aataacttca agaaagtttg tggaatacct ggcagattgc gtttttccat gtatcgcttg
      721 atagtatgga gacgattgac ataaacattg gccttttgac gtgcattaat atcatctttc
      781 tcaatttgtg tcaggcgctc actaactgaa atttgctcat cttcaatatc ttttagttga
      841 gtttgtaaat cctcaagatt ttcttcaaga actgaataag cttggggtgg ttcttcttga
      901 tttgaagtta cctcaacaat agctgcctca aaactctcta attctgtctg aatacgacga
      961 acatggcttg cagctgtctc aggaagtaaa taggtcttgt tcaaacgtgc aatatcttct
     1021 cccaataaag tattattctc tttcatatgt tgaagataag ttggaagagt tgcaagtaga
     1081 ttttccacta ctttctgagc agcaatttct cgagtaaaaa tatcatacaa ggcattgatt
     1141 tcctcttgtg cctgtccatt ctcatattcg gcattatcca attccaactg acgaatattc
     1201 tcttggtttt tcttgaatgc ttcataaagc aagtggaaac gcgcttcaat atccgtttca
     1261 acaaaatgat aattagcatc aattagttta cgataaccgg cttccaaatc ctgtaattga
     1321 tctggcaatt ctgtagaaag cgtcgtaacc aaggctggaa cacgatccac aatatgactt
     1381 aaggccaaaa tgtgattttc tgtattatcc aaaatcactg cggcttccac agggtcaccc
     1441 gatgaattca aggttacaaa ttgtgaaaat tcagattgga tattttctaa ttgtttttca
     1501 atttcatcca aggcttgacc atactgttct gaattttcag caactctatg ctgaagttcc
     1561 tcaaataaat ccaaagcatg aagaacacga ccactatttt tagattcttg cttctctaag
     1621 tctgccaaag cattgcgaat tgccgcaata tcttcttcaa tcaaagtaat ttgactctca
     1681 atttggtcaa tttgatgact ggccttgaga aaacgaaatg aatggttata accttctgct
     1741 tcaaagagat tattttcaat atcggcaaaa gagttgagag ataaatcgac ccatttttga
     1801 ttccattcac ggaaagccac ttgactttgt ccaatcaagt gcatattttt tacagcttct
     1861 acttcatcat ttactggaag attgtatagt tcttcttttt tttcttctag cgcctctaat
     1921 ctcccctcgt ttcgcttacg tagaaagatt gccactacat aagccagaac taaaatgact
     1981 gcaattgcaa ccattaaata aattagttgt ccattagaca tatcaaactc cttttttact
     2041 tgaaacaatc gtaacgatta tatcatattt tttagaccaa gggaactact tctccctatt
     2101 ttttagacat caagtgtact atagacagca ttttcttcga taaactcacg acgaggctct
     2161 actcgatccc ccatcaacat atcaaagatt ttatctgctt ctgcagcatc atctacagaa
     2221 actctagcca tcaagcgatg ttcgggatcc atggttgttt cccacagctg atgatcgtcc
     2281 atttcaccta gccccttata acgctgaata gtcggtttgg tacgaccttc actataacgg
     2341 gctaaagctt cttggagttt gatttcttga tctgcacccg gctggatata ttctttaatc
     2401 tcgcttccaa ccttgacacc atagattggt ggttgggcaa tataaacata accagcttct
     2461 aggattggtt tcatataacg ataaatcaag gttaaaagaa gggtacgaat atgggctcca
     2521 tcgacatcgg catcggtcat caaaacgagt ttttggtaac gggctttcga aacatcaaat
     2581 tctgcgccaa atcctgttcc catggctgtg aaaagactac gaatttcttc gttagctaga
     2641 atcttatcca tacttgcttt ttcaacgttc aaaatcttac cgcgaattgg aaggatagcc
     2701 tgaaactcac ggttacgacc agatttggct gatccaccag ctgagtctcc ttcgacgatg
     2761 aagagttctg tttcagcagg gttattagaa gaacagtctg ctagtttccc tggaaggttg
     2821 gaaatttcca aaccagattt tttacgtgtg acttcacgcg cacgcttggc agccacacga
     2881 gccttggcag ctaaaatccc tttttccacg atacgtttgg caatctgtgg attttccatg
     2941 aggaaatcgg agaaggcttc actgaagagg cgattggtaa tcttgaccac ttcgctattt
     3001 cccaatttgg tcttggtttg tccttcaaac tgtggatttg ggtgtttaac tgagataact
     3061 gcagttaatc cttcgcgaac atcttcccct gttaaattat cttcattgtc tttcagtaac
     3121 ttattcttac gagcataatc attgataaca cgagtcagtg ccgtacggaa accttgttca
     3181 tgcgttccac cttcatgggt atgaatatta ttggcgaaac tcatgacatt ttcatggtaa
     3241 cctgttgtgt actgcatggc tacctcaact gtaatatcat ccatctcacc gtctgtatag
     3301 attggtgtat caaagattac atccttgttc tcgttgatat attcaacgta actagcaatc
     3361 ccaccttcat aatgataatg cttggtttgt tccaaacctt ggcgcttatc agtgatagaa
     3421 atttgaagac cgcgatttag aaaggccaac tcttgaatcc gtttatttaa tttatcaaaa
     3481 tcaaaggttg ttgtttcagt aaagattttt gggtccggta tgaagtgaac cgttgttcca
     3541 gttctatctg tatccccaac cacctcaagg tctgcaacaa catgaccacg acggtattct
     3601 tggtaatgaa tcttaccgtt tttatggaca tgaacgtcta attgagtgga aagggcatta
     3661 actactgacg accccacccc gtgaagacca cctgaaacct tgtatccacc accgccgaac
     3721 tttcctccag catgaaggac tgtaaagacg gtctcaacag caggacggcc tgttttttcc
     3781 tgaatatcga ctgggatacc acgcccatca tccacaacag taatcgaatc atctggctca
     3841 ataaaaactt gaatatggct ggcaaatcct gccaaggcct cgtcaattga gttatcaaca
     3901 atttcccaga ctagatggtg aagaccttct tttgaggttg atccaatgta catccctgga
     3961 cgcatacgaa cagcctctaa accctctaaa acttgaattt gactggcatc ataatcctgt
     4021 gcctgcagat ttttgatttc ttctgtcatc ttattccttt ttcttatatg tctaatactt
     4081 gtcttaaatt cacgatactg gtaaacaagt gggtatcaag tcctgcagct tgacctgctt
     4141 cgatatcaat cggccgatca ccaatgacaa gaccagagct aatctgatac ttttctctta
     4201 aataaagcat ggattcggga tttggctttc tcttaaagcc tgagctagaa gtcaccactt
     4261 ctgtaaaata agctgctata gaggtttttt ctaaaatttc caaaacctga tcatttcgat
     4321 gagagaccaa aaaatgacgg ccaccttgat ttaaaatgtc ttccaatagg tcagaaactc
     4381 cttcaaataa aatcgggtgt tcaagctctc tggcttcatt ttccttgtac ttttctaaaa
     4441 aattctctaa attgggagcg aatgtctcaa tcgcaaaagg agtagaaacc tttaaagctt
     4501 gatagacact gtcatggtct tgtgtgatac catacagtgc caatgtttca acaaatgcag
     4561 ctgttgaagt ttcataatta tccagtaaag ttccacctaa atcccagatg taatcgtgat
     4621 atttcatacc cttcattata gcattttttt atgaaaaaag cgatgatttc cctgagtttt
     4681 ccacataaaa aacgagagaa taactcccgt tttactgatt tttaccaaag acatctcgat
     4741 agagcattcc tgttcgtaaa ctctctgcgt cccctcctag ttgctccacc aactcgtagg
     4801 caaaggcaag ggctgttgaa ggaccccgac tggttgtcaa ctgaccatct accactactg
     4861 tttccttgac gtagtgacca tcaaggattt gctcttgaac gccgtcataa caagtgtatc
     4921 gcttattttt caatatctct gcttgattga gggcaattgg tgccgcacaa atggctgcta
     4981 gtttcttccc ttcttgctcg aagctttgca attcttgaat caaggtctga ttatcacgta
     5041 aatgtgcaga accaggcata cctccaggaa gaacaatcat atcatagtct gataaatttc
     5101 catcaaagac atgatctgct cttacttgga ttgcatgcga acccgttact tgctcttcaa
     5161 aaccaaccat atcacatgtg atattggctc gacgcaagac atctacaact gtcaaggctt
     5221 caatttcttc aaagccctga gctaacataa ctgctacttt taccatgatt ttctccttat
     5281 ttaatttgtt ttaatacaac ctttttccgt ttgaatggga cttttccgct cttttcttca
     5341 gctagattag tctggtaact catcgataaa agcaaaccaa caccaatcag attactgata
     5401 atagctgatc ccccttgcga aatgaaaggc aagggaatcc ccgtcaaagg aagtagtcca
     5461 gtcacagcac cgatattctc aaagatgtgg aagagcaaca tcataatcaa acctgtggaa
     5521 atataagtgt agaactggtt atttgattta agagtaatct tcaacatacg gtaaatcaac
     5581 atgagataga gggcaataac caggacagag ccaataaagc caaaatcttc tgcaataacc
     5641 gtaaaaatca tatctgactc tcgaactggg ataagcagat tcgaagcatt aaatccctga
     5701 ccaaataagc caccactccc aatggcaatc tgcccttgag cctgctggta agtcgttgtt
     5761 tgggcaaact caaagggatt gagccaagcc aaaatccgat taatttggta ggtcggcatt
     5821 ccaatctggt gaagaaaagc tcgtccgtcc ttgctaataa agatagctaa gaaaccagca
     5881 actcctgtta cagcagtcac aaatactggg ataataattt tccaagaaac ccctgataat
     5941 aaaacgattc ctgagaaaat ggctacaaaa accaaagccg tccccaagtc actttgaagt
     6001 gctaaaagaa ctaggactgg aatggtaaag agaatcatac agaaaattaa caaaaagtcc
     6061 agcggaaccg tgcgtctcca ttccttatgt ttctttgtaa attggacaat gacacgagcc
     6121 aacatgagga tataggatat cttcataaat tctgacggtt ggaatagggt aattccattt
     6181 attgataccc agtttttggc acccgttgat gcaactaagc ttggattata aaatacaatc
     6241 ggcaagatca taagtcccaa gcctaaaata tatagaaagg gggtcacctt ccaaagaaat
     6301 tctgtattaa agagcatgac cacaaaacca atcacaagcc ccaaggcaat ccaggcgacc
     6361 tgctgcccta aaatgggcag aatattattg gggtaatcat gactaacggc tatatagata
     6421 gccaccacac cgatgaccag tagaaaaaat actggcaaga gcaaactgta atcgactctt
     6481 gagtcgagag aacgtttcat atatactaac cttatacttt catacaatac tatttatcaa
     6541 agttcattaa aaaatctatc aatagcctcg tcaacttcgg atcgagagat ggttttaaca
     6601 gtcgcttctt ctgctagaga tgctactatt tgtttgccgt atcgttttcc gacgattctc
     6661 ctatccaaaa taagagttaa ggaacgttgg tattcacgtc tcatacttct tcccaaagcc
     6721 tgttttaaac gaataatgac cattggcaat tgataatcat aaaaggcatt tttcccttct
     6781 tgattcagtt cttgattaat ctttttcgtc aagggttctt gaggattttg gaaaggaagc
     6841 ctcggtacaa cttgaatcac aaaaggatgg cttgaaaaat caactccctc ccagaaactt
     6901 gctgcaccaa gcaagatttg ttgttcacct ttttcaaagc gtttctttag ctgatgaaca
     6961 tccccatttt tatactgggc caagtggcta actgtaagta aatccgatac tgctagaagc
     7021 atgtctttag cggtaaagag aaccaaaatc ggttgctgga aagcttgaat ttccactagt
     7081 aaagcagcta cctctctggc atagacttct aaggaggttt ctgttaccag agggaaatct
     7141 ttgaccatga ccacttcttg ttcctgtttt ccccgagatt caatcttgac aaatttagct
     7201 tcaggatagc ctaaaaggtc tgccaaagaa accctctgac taatctcaag agtagccgat
     7261 actcccagga cttggcaact ctcaggaagt aaagaggaca gaagagtacg gcctgatttt
     7321 gtagaagaaa tctgaatttt cttttgactc gtttcagtta cttcaagcca gtaatcacct
     7381 tcagctgtaa aatagcgaac cagctcatca aagccttcta cttctaattc tgaaaaatac
     7441 tgatggagat tgtccagaga atctaagata tttttcctag atttaccaga ctgaaattgt
     7501 tctatcaagt agagacactc aaagcgaata ctttctagta tccgttgttg aaccctgttt
     7561 tcttctccta ctaaagcctt atcaattaaa tcgataatag attgtatatc gtaggtctct
     7621 tgaagcagat tttctagagc taacaaaatc ttttggactt catcaataat cagtaaacgg
     7681 tcactgacaa attcaggatt atcttcaagt ctggtcacga gataggcatg attagtcact
     7741 aaaagcttgc aagtctctgc cctttcttga ctacgtttcc aaaaatcttc cgtcacaaat
     7801 aagctctggg atgataaatt cccatcatga cgaaggtctg ctagaaaatg ttggtaacgg
     7861 tagagttgcc cgatttcatc caaatctcct gtctctgtct cagtaagcca gaccaagact
     7921 tgcattttaa agcgtctaaa taagcgattt tcatcatttt cctgcaagga atgataaaag
     7981 gcatccaact tcagataatt ttgtggtccc tttaagctat gaatatctgt atggaacact
     8041 tccttgagac gtttaccttc ttcttccatg atttgatttt gaagaatctt tgtcggaaca
     8101 ctaagaacaa tttgtcgctc tttggattga gataaagcgg gtaagagata gccataggtt
     8161 ttcccaatcc ctgtcggcgc ttgaatcaga aagacaggtt catctttcaa tagcaagcca
     8221 acctctttag caaaactttc ttgttcctcc ctcacttcaa ggttcaacag agaaatattt
     8281 ttagaaaagt cttgagatag ttttcgtagc tccagagaag ctgccgtttt cttaaaatac
     8341 agaccttgaa cttggaccaa gtctggagaa ctcaggatag attggttgcg ataagtttcc
     8401 tcaataacca ggtaggactc atataggaga gcgtcagcca tttccagcaa gcgttccaag
     8461 agacctttag gaagctgggt catcttttcc cgtaaaaaaa gaagtaattc tgctgtagct
     8521 tgggcatctg aaagggctgt gtgtgcgtgt ttaagaggaa ttcctaattc tcgacacaaa
     8581 atcggcaagc tatatttttc cagttcaggg aaaaagacct gggccaattc gaccgtatca
     8641 acacgagggt ttcttagctc atagccttca aaaaataaat tttccgccaa gagattagca
     8701 tcaaactgaa cattatgggc tacaaaaatc ccatcctcca ccaagtcaaa tatttttctg
     8761 gcaacttgcg aaaaatcagg tgcttgcgcc agacgttggt ctgtcaatcc tgtcagttct
     8821 ttgatatgag catccaaggg ttcatgtgga ttgacatccg tcgtatagtg atcgacgatt
     8881 tctccgtcct caatcacgac aattcccact tggataattt tagccttact acctgtgcta
     8941 gttgcctcta aatccaccac aacatagcga ttaccaatcg ttttcattat aaaaaattat
     9001 accaaaaaaa gggccatttg gcacctgcaa acataggata attttcaaac tcaagaacac
     9061 tacttttctt aaaaatccca tcgaatagag cattctagcc tgctgatttt tgtaaaatag
     9121 tgaagaaata cgaaaaattg agagaagaaa tgtttgcatc ttccttctct caacgaatca
     9181 tgtattttat ctaaccatgt caggatcgta gtcataaaat cctgtatcaa ggaaacggtt
     9241 tttagggtga agtttacgaa cttcttcatc cagcaagaag acttgatcat ggctaaagtt
     9301 gccctcttga atcaagttac gcgcttggat aaagagtttt gcaatctcaa caaagttctg
     9361 accaggagtg tagagccctt ctagtttcca gcgagtaaag ccatgctcca ccaattctgt
     9421 taatttgatc atcaaatcaa ggtcattgtt ggcaaagata tgggtcccat gattatcttc
     9481 aaaaatggaa tagtggctct ctggatcact tggctcagcc aagaagaggt cacgtttatg
     9541 cgtcttttca tcatcgatat gtgtaaagtt atagtagttt tgcaagagtg gacgtttaga
     9601 atgatggatg acgctagcac cgtaaaccaa aacttcagca ggaatttcca aaatctctgg
     9661 cattttgaaa agttcagctg atggaatttc acgcgccaaa acagcctcag atgcgccagc
     9721 cttttgtccc cagaagttaa tctgacgact gctagttacc atggttgaag catcgtagat
     9781 ggtcttaaat gaataaccat cgcggttaac tacgtaaaag acgcctgcat ccccaatcgt
     9841 aatatagtct atcttgattt cttccaagaa gtctaagaaa ggcttgatac ggtccatcat
     9901 atcttggtgc ataagagcat tgaccgcaac gatcaattcc ttaccagcat catgaaccaa
     9961 cttagcgatt tcacgtaatt ggtcataact aaaggtcgtt ggcagacgaa ggccaaaatc
    10021 tttctcaccg acatagatac ggtctacgcc agcttcgagt agttgttcaa cttgttcaat
    10081 actttcagca gttgctgtaa tgacaatctt ttccataaga aaaattatac cacatttctc
    10141 caaaatcatc catgctttga aaatgaaaag ggactttatt ctttttgtaa cctttctgta
    10201 ataattctct gccgaaaaaa tgataaaata ggtatgtact gttaaggaga gaattatgcc
    10261 cgtaagaaaa ttacaatcct atgaggtaga ctatcaagaa gaattaaacc agcagcttcc
    10321 tcattaccaa gcttatacac ctgaagcgca atctgatgcc aatctcaagg aaatcctatt
    10381 ttttattaat atcgctgttt tttgtatctg cattgctatc tttagtttta tctttttagc
    10441 attaaaatta tcaactgctc ttgcctttgc cgcagcaatc ggattcagct tacttgtttt
    10501 aaaagttcaa cggtctatta tcaaacgaaa acgtagaaga taaatccaaa atatcgcccc
    10561 agttggagcg atatttttat tttttctttt tagatggtgt ctgaatggca atcttcactt
    10621 caaaaattgt tcccttgggt ttattatctt tgacagtaac agttcctttt agagcatcta
    10681 caatttgctt ggctagggat aatcctaaac caaaaccacc tttttgccgg gttctagctt
    10741 tgtctactcg ataaaaacgg tcaaaaattt tctttttatc ttctgtcgaa ataccgattc
    10801 cattatcaga aacaagtaaa taaagattgc gatcggtcgc cgagataaga aaattaattt
    10861 caccatcctc ctcagtatac ttgacggcat tatcgaaaag aatggtcatc agttgtttca
    10921 gaagaagctg atctgtgaca attgttcgat ggatacgatt ttcaaaacgg aagacacgat
    10981 tattttccga agcaatcatc tcgtagtttg tgaaagttgt attaaaaaag ctagttggaa
    11041 cttctgcaag ctccggctta atcccatcat ctctccgagc taagttcagc aagcttgtcg
    11101 ttaaaaaacg catatttcgg acttcttcca aactcgatgc aatgctttcg ctcacatcca
    11161 taatggtagc ttctggctta cgaaaaaggg tctctaagcg attttgcaaa actgcgagtg
    11221 gagttcgtaa ctcatgactg gcattttcca caaaagactg ttgcttctgc atactctcaa
    11281 gcaggggcct aacactgacc ctagctagat agagactggc aagtaaagac aaaatccaga
    11341 aactagccat cacgaccaca atcaattgct catgcttttg actagcctgc tccaactgac
    11401 tggtattaat caagacagca gcatacttga tattggttga aaccgaacta atattggtct
    11461 ccatcaaaat cacacgatag atttcttcct gcccatagct attaaaaacc tgaatctggt
    11521 agatatgtcc tagttctttc ttttctaact taatcttatc caagcccaaa aatcgatttc
    11581 cagaaagaag ttgagtaaag tctttatcaa agagaatgac ttccgtattg gaactgacat
    11641 taggttttat ttctacttta ctagcgtccg ccctagcatt ttctaaatct ttaatctctt
    11701 ctgttgccct atttatagcc agctgaataa ctgcttgagg attttcactc agtccatgaa
    11761 gcttatcgtc caccgaagta taaagactcg aatgcatgac ttgtaaaata atcagagtca
    11821 ttgtagaaaa aatcagggtg aagacaccga agttgcggat aaaataacta aagtcatccg
    11881 cataccatgt ttttttaagt ttactgaaca tcttttaaaa gatacccaac actacgcaag
    11941 gtttgcaaat tctctgcaaa agtggttccc tttaatttct tacggacttt tgaaacatag
    12001 acttcgacaa ccgaaatcgt tgtatcacta tcaaatcccc atagacggtc aaaaatctgc
    12061 gtcttaggca aaatcacatt ttgattttga aggaaataaa ctagtaaatc gaactctttc
    12121 cccagcaatt cgacaggagt atcttcaact ttaacggtat tggttgataa attaaccacg
    12181 atattcccat aagtcaaggt gttttcatta aacttccctg aacgtttgag aagggcctga
    12241 atccgcattt taagttcttc taggtagaaa ggtttggtca gataatcatc cgctcccagt
    12301 tcaaatccat gtcccttgtc atccaaactt tccttggcag tcataatcag aactggtgtc
    12361 gtaattccct tttcacgcaa ttcttttaag acttggaaac catttttttc tggcaacatc
    12421 aaatccagca aaatcaagtc atagacacca ctctcagctt cgtagagacc ttcttctcca
    12481 tcaaatacct gcataacatc cgcaaaatcg tctaaaaagt caaatactga atttgacaga
    12541 cctaggtcat cctcaaccaa taagattttt atcatgagaa actcctcctt attaaaacta
    12601 ttataccaaa tttgccttaa aaaaaactca actctctgca ttttacggct ctataatatt
    12661 tgtagtgggt aaatcc
//
LOCUS       DBEJZV010000049        12432 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.49, whole genome shotgun sequence.
ACCESSION   DBEJZV010000049 DBEJZV010000000
VERSION     DBEJZV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12432
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.49"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..619
                     /locus_tag="ACL3S0_001911"
                     /pseudo
     CDS             1..619
                     /locus_tag="ACL3S0_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            811..3102
                     /gene="pcrA"
                     /locus_tag="ACL3S0_001912"
     CDS             811..3102
                     /gene="pcrA"
                     /locus_tag="ACL3S0_001912"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGR1312773.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYCADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVAEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASIEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            3145..3825
                     /gene="radC"
                     /locus_tag="ACL3S0_001913"
     CDS             3145..3825
                     /gene="radC"
                     /locus_tag="ACL3S0_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGR1312774.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3822..4511)
                     /locus_tag="ACL3S0_001914"
     CDS             complement(3822..4511)
                     /locus_tag="ACL3S0_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR1312775.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4529..5170)
                     /locus_tag="ACL3S0_001915"
     CDS             complement(4529..5170)
                     /locus_tag="ACL3S0_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGR1312776.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(5253..5468)
                     /locus_tag="ACL3S0_001916"
     CDS             complement(5253..5468)
                     /locus_tag="ACL3S0_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR1312777.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5476..5823)
                     /locus_tag="ACL3S0_001917"
     CDS             complement(5476..5823)
                     /locus_tag="ACL3S0_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGR1312778.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5828..6943)
                     /locus_tag="ACL3S0_001918"
     CDS             complement(5828..6943)
                     /locus_tag="ACL3S0_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR1312779.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6953..7912)
                     /locus_tag="ACL3S0_001919"
     CDS             complement(6953..7912)
                     /locus_tag="ACL3S0_001919"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR1312780.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(8025..8594)
                     /locus_tag="ACL3S0_001920"
     CDS             complement(8025..8594)
                     /locus_tag="ACL3S0_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGR1312781.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8722..9393
                     /locus_tag="ACL3S0_001921"
     CDS             8722..9393
                     /locus_tag="ACL3S0_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGR1312782.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            9377..10195
                     /locus_tag="ACL3S0_001922"
     CDS             9377..10195
                     /locus_tag="ACL3S0_001922"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGR1312783.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            10192..11088
                     /locus_tag="ACL3S0_001923"
     CDS             10192..11088
                     /locus_tag="ACL3S0_001923"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR1312784.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            11132..12106
                     /gene="pta"
                     /locus_tag="ACL3S0_001924"
     CDS             11132..12106
                     /gene="pta"
                     /locus_tag="ACL3S0_001924"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGR1312785.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3653 a         2383 c         2667 g         3729 t
ORIGIN      
        1 gagaataccg cacttatgaa gaaattgcgg ctgatcttgg tattcacgaa agcaacttac
       61 tccgtcggag ccaatgggtt gaagtaactc ttgttcaaag tggtgttacg atttcaaaaa
      121 ctcatcttag tgctgaggat acggtgattg tggatgcaac agaggtaaaa ataaatcgtc
      181 ctaaaaaaat caactagcca atcattctgg taaaaagaaa tttcacgcta tgaaggctca
      241 agcgattgtc acaagtcaag ggagaattgt ttctttggat atcactgtga actattgcca
      301 cgatatgaag ttgttcaaaa tgagtcgcag aaatatcgga caaactggta aaaccttggc
      361 tgacagtaat tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc
      421 cagcaaactc aaaccgctaa cagttaaaga taaagcctat aaccatgcgt tatctaagga
      481 gagaagcaag gttgagagca tccttgccaa agtaaaaacg tttaaaatgt tttcaacaac
      541 ctatcgaaat catcgtaaac gcttcggatt acgaacgaat ttgattgctg gcattatcaa
      601 tcatgaacta ggattctagt tttgcaggaa gtctattgag gtattgagct agtttatgaa
      661 aaaattgggt gaaaaagtcg agtgttttag aaacccacag tgtagtattc tagtttcaat
      721 ccactatatt ttgctactcc ccgtaaagtt tctattttcc ctgatttctg atataataga
      781 aatattgact tcaagagtaa ggaagagaag atgaacgcat tattaaatgg aatgaatgac
      841 cgtcaggctg aggcggtgca aacgacagaa ggtcccttgc taatcatggc aggagctggt
      901 tctggaaaga ctcgtgtttt aacccaccgt atcgcttatt tgattgatga aaagctggtc
      961 aatccttgga atatcttggc cattaccttt accaacaagg ctgcgcgtga gatgaaagag
     1021 cgtgcttata gcctcaatcc agctactcag gactgtctga ttgcgacctt ccactccatg
     1081 tgtgtgcgta ttttgcgtcg cgatgcggac catattggct acaatcgtaa ttttacaatt
     1141 gtggatcctg gtgaacagcg aacgctcatg aaacgtattc tcaaacagtt gaacttggat
     1201 cctaaaaaat ggaatgaacg aactattttg gggaccattt ccaatgctaa gaatgatttg
     1261 attgatgatg ttgcttatgc tgcccaagct ggcgatatgt atacgcaaat tgtggcccag
     1321 tgttatacaa cctatcaaaa agaacttcgt cagtctgaat ccgttgactt tgatgatttg
     1381 attatgctga ccttgcgtct ctttgatcaa aatcctgatg ttttgaccta ctaccagcaa
     1441 aaattccaat acatccacgt tgatgagtac caagatacca accacgctca gtaccaattg
     1501 gtcaaactct tggcttcccg ttttaaaaat atctgtgtgg ttggggatgc ggaccagtct
     1561 atctacggtt ggcgtggtgc tgatatgcag aatatcttgg actttgaaaa ggattacccc
     1621 aaagccaagg ttgttttgtt ggaagaaaat tatcgctcaa ccaaaaccat tctccaagcg
     1681 gccaacgagg ttattaaaaa caataaaaat cgccgtccta aaaatctctg gactcaaaac
     1741 gctgatgggg agcaaatcgt ttactattgt gccgatgatg agctggatga ggctgtattt
     1801 gtagccagaa ccatcgatga acttagtcgc agtcaaaact tccttcataa ggattttgca
     1861 gttctctatc ggactaatgc ccagtcccgt acaattgagg aagccctgct caagtctaac
     1921 attccttata ccatggttgg cggaaccaaa ttctacagcc gtaaggaaat tcgcgatatt
     1981 attgcttatc tcaaccttat tgctaatttg agtgacaata ttagttttga gcgtattatc
     2041 aacgagccta aacgtggaat tggtccaggt acagttgaga aaatccgtga ttttgcaaat
     2101 ttgcaaaata tgtctatgct ggatgcttct gctaatatta tgttgtctgg tatcaagggt
     2161 aaggcagccc aatctatctg ggattttgcc aatatgatgc ttgatttgcg ggagcagcta
     2221 gaccacttaa gcattacaga gttggttgag tccgtcctag aaaaaacagg ttatgtcgat
     2281 attcttaacg cccaagcgac tctagaaagc aaggctcggg ttgaaaatat cgaagagttt
     2341 ctttctgtta cgaagaactt tgatgacacc actgatgtgg cagaagagga aactggtctg
     2401 gacaaactga gtcgtttctt aaatgacttg gctttgattg ccgacacaga ttcaggtagt
     2461 caggagacat cagaagtgac cttgatgacc ctgcatgctg ctaaaggtct cgaatttcca
     2521 gttgtctttt tgattgggat ggaagaaaat gtctttccac ttagtcgtgc gactgaagat
     2581 ccagatgaat tagaagaaga gcgccgtcta gcctatgtag gtatcacgcg tgcagagaaa
     2641 attctctatc tgaccaatgc caactcacgc ttgctttttg gtcgtaccaa ttataaccgt
     2701 ccgactcgtt ttattaacga aatcagttca gacttgcttg agtatcaagg tctggctcgt
     2761 cctgcaaata caagctttaa ggcatcatat agcagtggta gtatttcctt tggtcaaggt
     2821 atgagtttgg ctcaggctct tcaagaccgt aaacgcggtg ctgccccaaa atcaatccag
     2881 tcaagcggtc ttccatttgg tcaatttaca gctggcgcaa aatcagcatc tatcgaggca
     2941 aattggtcca ttggtgacat tgctctccac aagaaatggg gagagggaac cgttctggaa
     3001 gtttcaggta gcggtgctag gcaggaattg aaaatcaatt tcccagaagt aggtttgaaa
     3061 aaacttttag ccagtgtggc tccaattgag aaaaaaatct aattttccat ccttctcacg
     3121 aataataaag tgaggaggat ttttatgtac agtatttcat tccaagaaga ttcactatta
     3181 ccaagagaaa ggctggccaa ggaaggagtt gaagcgctta gtaaccaaga gttgctagct
     3241 attttactca ggacaggaac acgtcaagct agcgtttttg aaattgccca aaaagtcttg
     3301 aacaatcttt caagcctaac ggatttgaaa aaaatgaccc tgcaggaatt gcagagtttg
     3361 tctggtattg ggcgtgttaa ggccatagaa ttacaagcta tgattgaact ggggcatcgt
     3421 attcacaaac acgagactct tgaaatggaa agtattctca gcagtcaaaa gttggccaag
     3481 aagatgcagc aggaattagg ggataaaaaa caagagcacc tggtggcact ctatctcaat
     3541 actcaaaatc aaatcatcca tcagcagacc atttttatcg gttctgtaac tcgtagtatc
     3601 gctgaaccgc gagagattct tcactatgca atcaagcaca tggcgacttc tcttatcttg
     3661 gtccacaatc atccttcagg agcggtagcg cctagccaaa atgatgatca tgtcactaaa
     3721 cttgttaaag aagcctgcga actgatgggg attgttctct tggaccattt gattgtctct
     3781 cattctaatt actttagtta tcgtgaaaag acagatttaa tctaaagttc attaacgaca
     3841 tagtcaaaga gtttcttatc tttgggacga ttttcaaaaa gaagttctgg atgccattgg
     3901 acaccgagaa aggcgacatc atccgtactc atgacagcct caatgatacc atctttagga
     3961 tcatgagcca caacttttaa atttggtgct aagtccttga tgctctggtg gtggaaggag
     4021 ttgatatgag agatttctcc atagatttct tggagaacgg tatctggttc tgtcaccaag
     4081 cgttgagttg tgtactcaac agaagaatcc tgccaatggt cttcgatatc ttggtacaaa
     4141 gttccaccca tggcaacgtt aaagagttgg gtaccacggc agacagagaa aatgggcttt
     4201 ttctgtttaa tagcttcctt gatgagggcc agttcgaaga tatctctttg aaggtgataa
     4261 tcatcgctat caatggtttt gggttcgcca tagaattttg gatcgacatt ttgcccacct
     4321 gtcaagatga gcttgtcaat caaactgata tagtggcagg ccatttcttg atcaccaatc
     4381 ggtaggatga taggaatccc tccagcatct ttaacgcctt caacaaagcc ttttgctgcg
     4441 tagctcatca tgatgtcatc atctggatga gttttttcgt ttcctgtaat cccaataact
     4501 ggttttttca taaaatgatt ttcgctttct aatcctcttt tcgcatgaag tagaggaggg
     4561 tttggagttc acttgtcaaa tcgacatact gaacgaccac gtcttttggt aaatgcagat
     4621 ggactggtga aaaactgaga attcctttca caccagcatc aaccaagaga ttagcaacct
     4681 cttgtgactt gacgctggga acagttagga tagcagtctt cacatcagca tccttgattt
     4741 tatccttgat ctgagaaatc ccgtaaatgg gaatcccgtc aggagtttgg gtaccgactt
     4801 caggatggtc gtctaggtca aaggccatga taatcttcat cttgttacgt tcgtggaagc
     4861 ggtagtggag aagggcatgg cccatatttc caataccaac cagcatgaca ttggtaatag
     4921 agttgtcatt gagcaaatcg gcaaaaaatg tcattagttt tttgacatca tagccaaaac
     4981 cacgacgacc aagttcacca aaataggaaa aatcacgacg tacggtcgct gaatcaatcc
     5041 caatggcctc tgcaatttgc ttagagttgg cacgttcaat cttttctgca tgaaatctct
     5101 taaaaattcg atagtagaga gagagtcttt ttgctgtagc ttttggaata gcaaactgtt
     5161 tatctttcac aaaatcacaa cctttctatt cttctatttt atagaaacat tgtgaaaaaa
     5221 tcaacaaaaa taagaaaaaa ctaagaaaaa tcttagtttt gatgtaaaaa atctgcatga
     5281 gatagaaaac ggtagaggtc tccgaccagc ccctgataaa cttttttgcc cctaaaagtc
     5341 agagaagtca cataaagtgt atctggtaag gttacacatc ctgacaaagt caacatgaga
     5401 gcctcatgat cctcatactt gagagtacgc tctacatgat agcagtcctt ataggtcagt
     5461 tcaaacattt tggctctatc tttccgattt tgtaaagaca ccacgttcta ccaagctatc
     5521 catgaggaag tagaattttt cctgatgaat atggtggtct tctgatttga aaatatcaac
     5581 tagacgaagg ccaaacttgt cagtgatatt gattttagcc cctgtaagtt ccttgttaat
     5641 gatgattttg agttggaagc cttcaccgct gtttggcact ttttccaaaa ggcgagtcag
     5701 ttcatagtta ccaaccttag tttcaaaaaa ggtgttatct ttgagggtga attttttaac
     5761 agaagggcta agagtgtaat cgtaacgaca attttttaac tgaatgattt tttcaaatgc
     5821 catatggcta acctccgata atttctttta aggtttttgc gagggtttgt aggtcttcaa
     5881 cggtattttg tggcgacaaa ctgatgcgaa gggattcctt caagcgttct gaatttgcgc
     5941 catacatggc ttcaagaaca tggctggatt ggacaacgcc tgcagtacag gctgagccag
     6001 tagagattga aattccagct aaatctagcc gaaggagtaa gaggtcattt ttctgaccag
     6061 gaaatccaat attgagaaca taagggagat gatgttttcc tctattcaag taatactgaa
     6121 tgccctccag ctctgccaga aaggcagttt ctagattttg tacatgttga aaatgttctt
     6181 cttgtttttc taggtcttct tttagggctg caaccatgcc tacgatagca ggcagatttt
     6241 cagttcctgc acgttttttc tgttcctggt ctccgccatg tagataggaa tcaaagtcca
     6301 tgctagatgc gtagagaaaa ccgattccct taggaccatg gaatttgtgg gcagaagcag
     6361 tgagaaaatc aatgcccaat tcttctgaat gaattgggat tttaccaata gcctgaactg
     6421 catcaacatg ataggcagca gggtgttgct tgagtatttg gccaatttca gcgatgggca
     6481 gtaggtttcc tgtctcatta ttggcaaaca tggtagaaac caaaatcgta tcgtcacgta
     6541 aagccttttg aatttgctgg gctgtgattt cttgattttc tggctggata atggttgctt
     6601 caaacccaaa gtgttgaacc aagtaatcaa ttgtttcaag gacagcatgg tgctcgatgg
     6661 cagttgtgat gatatgtttt ccttgttctt ggtgacgaag acagtagcca atgatggtag
     6721 tattattgcc ttcagtccca ccagaagtga aaaagatatg ttgaggtttt gtccttagta
     6781 actgggctag ttcctgacgg gcttctcgca agagtttgcc agcttgacga ccatgaccat
     6841 gaatactaga aggatttccg tgggtttctt gcataacctt ggtcatagct gaaatagcaa
     6901 ctgctgacat aggagtcgtt gcagcattgt ccaaataaat caaagaatca ccttatttct
     6961 ttttattgta ggcaaagagt gggctgactg gttttctttc gtgaatacgg acgatagcat
     7021 caccaattaa ctcactagca gtgatgtagc atacattttt aggagttttt tcttttgttg
     7081 ctactgaatc agtcacaaga atttctttaa tattagtatt gtcaagaagc tcagcagctc
     7141 cctcgacgaa gagaccgtgg ctagaaacag cataaatttc tgtagctcct tcacgttcaa
     7201 cgattttaga agcttcagag aaggtacgtc ctgtatttaa aatatcatca atcaagatag
     7261 ctttcttacc ttcaacatca ccaataatat aaccttcgtt acgagttgca tcgtcttgag
     7321 ggtagtcgat aatggcgata ggagcatcaa gatattcagc caggctacgc gcacgtttga
     7381 cacctgaatt tttagggcta acgacaacaa catctgaacc aagcaatcct ttatcgcagt
     7441 aatgttttgc gaatagggga acagtgaaaa gattatccac tggaatatca aagaaacctt
     7501 gaacctgaac ggcatgcaaa tcaagagtca ggatacgatc aactccagcc ttaaccagca
     7561 tattggcaac tagttttgct gtaagtggct cacgaggaca agcaatgcgg tcttgacgtg
     7621 catagccaaa atatggaagg acaacgttga tactgtgggc acttgcacgc acacaagcat
     7681 cgaccatgat taacaattcc attaggtggt tgttgacagg gaaacttgtt gattggatga
     7741 tgtaaacatc ataaccacgg acactttctt cgatatttac ttggatttct ccgtctgaaa
     7801 attgacgtga tgatagtttt ccaagtggga caccaacagc ttgggcaatt ttttgtgcaa
     7861 tctcttggtt agagttgagt gcgaaaagtt tcatgttttt tctatctgac attatagacc
     7921 gtcctctgta aactttataa atcctagtta tatttacctt acatatatga actgggattt
     7981 gtgtattttt atcttttcta ttttaccaaa aaatggagat tatttcagct atttttcata
     8041 cttttgacaa atcgaaccaa ttttgaagga gctttttggt aggaaatctg atttttctct
     8101 aaaaattgtc ggaaatcctg tttgccttgc tcatgatttt ccacttcaag ctccaattcg
     8161 taatctgtta tatcaaagta tcggctctga tccagtgcca tgagaccaat agctgttttc
     8221 atttcatagc gaagcgttgt tagacaacca agaacctgcc agttcttact ttggatacca
     8281 tgtttcgcca attcatccag tactagccct tgaggaagtt cttccttact cagatagttc
     8341 tcagcatctt ttagttgtaa tttttggttg tattccatgt ttccaacact ctgcgggact
     8401 ttgagtgtca attcagccca gtcttcaaag gttcgaatgc gcatagcgac tttcttttct
     8461 cgcagttcaa aatcaggcgt gtcgatgtag taatttgttt gaagaacagg agtgacacct
     8521 gtgaactggt cttttagacg attgtattca tcttttttca atagtgtttt caattcaatt
     8581 tctaaatgtt tcatttttct tacctttttt tatcgttgaa agcggattta tggtataata
     8641 agcattgtat ttattgtata tgaatctgga gaaaaaatca aagatatttt tgacggataa
     8701 tatgagaaca agggagaata tatgacctta gaatgggaag aatttctaga tccttacatt
     8761 caagctgttg gtgagttaaa gattaaactt cgtggtattc gtaagcaata tcgtaagcaa
     8821 aataagcatt ctccaattga gtttgtgacc ggtcgagtta agccaattga gagcatcaaa
     8881 gaaaaaatgg ctcgtcgtgg cattacttat gcgaccttgg aacacgattt gcaggatatt
     8941 gctggcttac gtgtgatggt tcagtttgta gatgacgtca aggaagtagt ggatattttg
     9001 cacaagcgtc aggatatgcg aatcatacag gagcgagatt acattactca tagaaaagca
     9061 tcaggctatc gttcctatca tgtggtagta gaatatacgg ttgataccat caatggagct
     9121 aagactattt tggcagaaat tcaaattcgt actttggcca tgaatttctg ggcaacgata
     9181 gaacattctc tcaactacaa gtaccaaggg gatttcccag atgagattaa gaagcgactg
     9241 gaaattacag ctagaatcgc ccatcagttg gatgaagaaa tgggtgaaat tcgtgatgat
     9301 atccaagaag cccaggcact ttttgatcct ttgagtagaa aattaaatga cggtgtagga
     9361 aacagtgacg atacagatga agaatacagg taaacgaatt gatctgatag ccaatagaaa
     9421 accgcagagt caaagggttt tgtatgaatt gcgagatcgt ttgaagagaa atcagtttat
     9481 actcaatgat accaatccgg atattgtcat ttccattggc ggggatggta tgctcttgtc
     9541 ggcctttcat aagtacgaaa atcagcttga caaggtccgc tttatcggtc ttcatactgg
     9601 acatttgggc ttctatacag attatcgtga ttttgagttg gacaagctag tgactaattt
     9661 gcagctagat actggggcaa gggtttctta ccctgttctg aatgtgaagg tctttcttga
     9721 aaatggtgaa gttaagattt tcagagcact caacgaagcc agcatccgca ggtctgatcg
     9781 aaccatggtg gcagatattg taataaatgg tgttcccttt gaacgttttc gtggagacgg
     9841 gctaacagtt tcgacaccga ctggtagtac tgcctataac aagtctcttg gcggtgctgt
     9901 tttacaccct accattgaag ctttgcaatt aacggaaatt gccagcctta ataatcgtgt
     9961 ttatcgaaca ctgggctctt ccattattgt gcctaagaag gataagattg aacttattcc
    10021 aacaagaaac gattatcata ctatttcggt tgacaatagc gtttattctt tccgtaatat
    10081 tgagcgtatt gagtatcaaa tcgaccatca taagattcac tttgtcgcga ctcctagcca
    10141 taccagtttc tggaaccgtg ttaaggatgc ctttatcggt gaggtggatg aatgaggttt
    10201 gaatttatcg cagatgaaca tgtcaaggtt aagaccttct taaaaaagca cgaggtttct
    10261 aagggattgc tggctaagat taagtttcga ggtggagcta ttctggtcaa taatcaaccg
    10321 caaaatgcaa cgtatctatt ggacgttgga gactacgtta ccatttacat tcccgctgag
    10381 gaaggctttg aaaccttgga ggctattgag cttccattag atattctcta tgaggatgac
    10441 cactttctag tcttgaataa accctatgga gtggcttcta ttcctagtgt caatcactct
    10501 aataccattg ccaattttat caagggttac tatgtcaagc aaaattatga aaatcagcag
    10561 gttcacattg ttaccagact agatagggac acttctggct tgatgctctt tgccaagcac
    10621 ggttatgccc atgcacgatt agacaagcag ttgcagaaga aatctatcga gaaacgctac
    10681 tttgctttgg ttaagggaga tggacatttg gagccagaag gggaaattat tgctccgatt
    10741 gcgcgtgatg aagattccat tattaccaga cgagtggcta aaggcgggaa gtatgcccat
    10801 acttcataca agattgtagc ttcttatgga aatattcact tggtctatat tcacctgcac
    10861 actggtcgaa cccatcaaat ccgagtccat ttttctcata tcggttttcc tttgctggga
    10921 gatgatttgt atggtggtag tctggaagat ggtattcaac gtcaggctct gcattgccat
    10981 tacctatcct tttatcatcc atttttagag caagacttgc agttagaaag tcccttgccg
    11041 gatgatttca gtaaccttat tacccagtta tcaactaata ctctataaaa actgtctcag
    11101 agtataatta ttatcttaaa ggagaaaact catggaagtt tttgaaagtc tcaaagccaa
    11161 ccttgttggt aaaaatgctc gtatcgttct ccctgaaggg gaagagcctc gtattcttca
    11221 agcaacaaaa cgcttagtaa aagaaacaga agtgattcct gttttgcttg gaaatcctga
    11281 aaaaattaaa atttatcttg aaattgaagg aatcatggat ggttatgagg tcatcgaccc
    11341 tcaacattat cctcaatttg aagaaatggt ttctgccttg gtggagcgtc gcaagggcaa
    11401 aatgactgaa gaagatgtac gcaaggtttt ggttgaagat gtcaactact ttggtgtgat
    11461 gttggtttac ttgggcttgg ttgatggaat ggtgtcagga gcgattcact caacagcttc
    11521 aacagttcgc ccagctctac aaatcatcaa aactcgtcca aatgtaactc gtacttcagg
    11581 agccttcctc atggttcgtg gtacggaacg ttacctattt ggagactgtg ccattaatat
    11641 caatccagat gcagaagcct tggctgaaat tgccatcaac tcagcaatca cagctaagat
    11701 gtttggcatc gaacctaaaa ttgccatgtt gagctattct actaaaggtt cagggtttgg
    11761 tgaaagcgtt gataaggtcg ttgaagcaac taaaattgct cacgacttgc gtcctgacct
    11821 tgaaatcgat ggtgagttgc aatttgatgc ggcctttgtt cccgaaactg cagctctgaa
    11881 agctccggga agtacagtag ctggtcaagc aaatgtcttc atcttcccag gtatcgaggc
    11941 aggaaatatc ggttacaaga tggctgaacg cctgggtggc tttgcggctg taggacctgt
    12001 tttgcaaggt ttaaacaagc cagttaatga tctttctcgt ggatgtaatg cagatgatgt
    12061 ttacaagttg accctcatca cagcagctca agcagttcat caatagtgaa aactataaag
    12121 tgatatacta tgctatactg tagttatgaa actatgtacg aaaagcactg ccattaattc
    12181 ctgagaacta aattactgat tggtgtcaaa aaggaaaact tccaagcgat gatatcctgt
    12241 ctatacacga cctatagaaa tctgtaatat acatatccgt aaaacgataa attccctttt
    12301 tgattttaaa tgagtatgaa aagagaattt tttggctctt tgtcaactgt agtgggttga
    12361 agaaaagcta agctcgagaa aggacaaatt tcgtcctttc ttttttgatg ttcaaagcga
    12421 taaaaatctg tt
//
LOCUS       DBEJZV010000050        12027 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.50, whole genome shotgun sequence.
ACCESSION   DBEJZV010000050 DBEJZV010000000
VERSION     DBEJZV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12027
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.50"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(156..1358)
                     /gene="rpsA"
                     /locus_tag="ACL3S0_001925"
     CDS             complement(156..1358)
                     /gene="rpsA"
                     /locus_tag="ACL3S0_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGR1312786.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1520..1591)
                     /locus_tag="ACL3S0_001926"
     tRNA            complement(1520..1591)
                     /locus_tag="ACL3S0_001926"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1557..1559),aa:Gln,seq:ttg)
     gene            complement(1601..1681)
                     /locus_tag="ACL3S0_001927"
     tRNA            complement(1601..1681)
                     /locus_tag="ACL3S0_001927"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1645..1647),aa:Tyr,seq:gta)
     gene            complement(1731..1961)
                     /locus_tag="ACL3S0_001928"
     CDS             complement(1731..1961)
                     /locus_tag="ACL3S0_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGR1312787.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2129..2773)
                     /gene="pcp"
                     /locus_tag="ACL3S0_001929"
     CDS             complement(2129..2773)
                     /gene="pcp"
                     /locus_tag="ACL3S0_001929"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR1312788.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2788..3711)
                     /locus_tag="ACL3S0_001930"
     CDS             complement(2788..3711)
                     /locus_tag="ACL3S0_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGR1312789.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3708..4397)
                     /locus_tag="ACL3S0_001931"
     CDS             complement(3708..4397)
                     /locus_tag="ACL3S0_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGR1312790.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4462..5166)
                     /locus_tag="ACL3S0_001932"
     CDS             complement(4462..5166)
                     /locus_tag="ACL3S0_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1312791.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKCGNVAPSQKDYDLNSTGWAPSYQDPASYLNIIDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDILTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(5222..6244)
                     /locus_tag="ACL3S0_001933"
     CDS             complement(5222..6244)
                     /locus_tag="ACL3S0_001933"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGR1312792.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6376..8847)
                     /gene="parC"
                     /locus_tag="ACL3S0_001934"
     CDS             complement(6376..8847)
                     /gene="parC"
                     /locus_tag="ACL3S0_001934"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGR1312793.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9048..9252)
                     /locus_tag="ACL3S0_001935"
                     /pseudo
     CDS             complement(9048..9252)
                     /locus_tag="ACL3S0_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(9267..11210)
                     /gene="parE"
                     /locus_tag="ACL3S0_001936"
     CDS             complement(9267..11210)
                     /gene="parE"
                     /locus_tag="ACL3S0_001936"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGR1312794.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11346..11987
                     /gene="plsY"
                     /locus_tag="ACL3S0_001937"
     CDS             11346..11987
                     /gene="plsY"
                     /locus_tag="ACL3S0_001937"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGR1312795.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3463 a         2721 c         2123 g         3720 t
ORIGIN      
        1 ttcaaaaaac ggatttttat cgctttgaac atcaaaaaag aaaggacgaa atttgtcctt
       61 tctcgagctt agcttttttc aacccactac agttgacaaa gagccgaaaa atcccttgtt
      121 tagtaaacaa aggattttgt gaattttcaa tttgattaaa gttcgatatc accaaacaaa
      181 tcagccattg aaaatcctgt ttgtgtttct ggaagttcga aatcacgctt ttcttgacgt
      241 cttggacgac gtggacgagc agcacgtttt tcttcttttt gtccttcttc ttgggctgga
      301 cgttcttcaa gagctttaat agaaagtgat acgcgttctg catctgcgtt aacttcaaga
      361 actttaactt gaacttcttg accaacttta agagcttctt ttggattttc aatccgtttg
      421 tgtgaaattt gtgatacgtg aacaagtcca tcgatacctg gcaatacttc aacaaatgca
      481 ccgaagtcag tcaaacgttt aactgttcct tctactacat cacctttagc caatttttgc
      541 tcaacgccat cccatggtcc tggtactgtt gctttaagtg aaagtgatac acgtccttct
      601 tcttcgttaa gatcaaggat tttcacttca atttcttcac caacagttac aactgatttt
      661 ggtgatacgt tacgttcatg tgacaattca gtcaagtgaa ccaatccgtc aacaccacca
      721 aggtcgatga aagcgccgaa gcttgtgata cgagcaactt taccagttac aacatcacca
      781 acagccaatt taccgaatac ttcagcgcga gctgctgcag tagctgcttc aacaacttca
      841 cgacgtgaaa ggatgaagcg gttttcttta gcgttaactt ctttgatttt agtatcaaat
      901 tcttgaccta caaaacgctc agcgttacgt acgaaacgag tatccaacat tgaagctggg
      961 ataaatccac gaacaccttc aaattctact gaaagtccac ctttaacggc acgcgttcct
     1021 ttaacagtaa caacttcttc ttcgcgacca acaagtttgt cccatgcttt gcgagcttca
     1081 aggcgttttt tagatacaag gtatgtaact gtatcagtat ctttaccaac tacttgacga
     1141 agtacaagaa catccaatac ttctcctact ttaacaaagt cattgatatc tgcatcacga
     1201 tcgtttgtca attcgcgaag agtcaagaca ccttcaacac cagttccaga gattgcaacg
     1261 ttagcttgag ttgcatcaac tgtcaatact tcagcactaa caacatcacc agtctcaact
     1321 tgactaacgc tatttagcaa atcttcaaat tcgttcatct aaaaaatcct ccaacaatca
     1381 agtttttctt aaacttgaca tacttataat ttttttccta agcacccgca aggacatgtt
     1441 catatcattc acgtctttca attataaaaa taaaataccc taagatattt tgctttttat
     1501 cttgattatt acctaagaac tggggtagct ggattcgaac caacgcatga gggagtcaaa
     1561 gtcccttgcc ttaccgcttg gctatacccc attaatgaaa tggagagaga gggattcgaa
     1621 cccccgaacc cgaaggagcg gatttacagt ccgccgcgtt tagcctcttc gctatctctc
     1681 ctacaatcaa catggactat tatatcatga aaatttcaaa aaaacaagac ttattttgct
     1741 aaattataat tttcaatcaa aatttccaca gctttttcca attttttata aaaactatcg
     1801 acattcccat tctttataat ggcaaattgt ccgtctaatt cggcaatttc tccgataact
     1861 tttttaccga tagtcaatgt ataaccttca aaactgtctt taccaacatt aactttggca
     1921 tccgctactt gaatttcgat ttttttatct ttcttgctca tttcatacct ctcttcactt
     1981 tttctatttt acaagaaaat cctaaaacta gcaagaaaaa actctatatc aggcttctct
     2041 gatatagagt tttatgtaaa caacctcaat cgatttagca tagctaatag ttagtaaaca
     2101 agcataattg actatccttt ctaggttatc agtgagtctc accgcctact aactgcaaat
     2161 ccttatcttt gtagtctaca atagcttcaa tagctacctc tatgcctctt acaatatcac
     2221 atagactcat tcctgcagta ttcggcttat ttactacttg ttccatcata tatggaatat
     2281 gcatgaaacc tgctctcata ttagggaatt ttttatccac taaataaaga gcttggtaca
     2341 tcaaatgatt gcaaacaaag gttcctgcac tattggatac aactgccgga agtccctgtt
     2401 ttttgatagc ttgtaccatc gctttgatag gtaaactact aaaataggcc gatgctccat
     2461 caatacgaat cggtgtatca attggttgat tgccttcgtt atcaggtatg cgagcatcat
     2521 cttgattaat agccactcgt tcaggtgtta agccggtcct gccgcctgct tgtccaatac
     2581 aaagtacagc atctggttga tatcgtaata tttctgcctc taaaacttct gacgacttat
     2641 aaaaaaccgt tggaatttct acccagcgaa cttcagcccc attaatctca gatggtaata
     2701 attttacagc ctccaaagct ggattaatct tttcacctcc aaaaggatta aaacctgtaa
     2761 ccaatatttt cattttattt tcctttacta aaatgcgaga aagtacatta agaatatgtg
     2821 aataacaatc attactagag caacacctgc ttgagccttt ataacgccat tctgatcttt
     2881 catatccatc aatgctgctg gtagagcgtt aaaattagca gccattgggg tcaataaggt
     2941 cccacaataa cctgctgtca tggcaagagc accagccaca attggattag ctcccagagc
     3001 aaatacaaag ggaactccaa cacctgctgt aataacggtg aatgctgcaa aagcatttcc
     3061 cataatcatt gtgaatagaa ccattccaag aacataggcc aaaactccta taaagcgact
     3121 atctgaagga acaataccgc taatcagatg agagataaca tcaccaacac ctgctacagt
     3181 aaaaatagcc cccaaagccc ctaataattg aggaacaata ccacttgttg aaacttgctg
     3241 agtcattcga ttattttctg ataacagact cttagggtga ctattggtaa tcacaagaac
     3301 agaaattgta gcaaacaagg cggcaaggct aatcgaaatc ttgctaaatt ctggaatcat
     3361 ttgcgctaag accaacgcaa gtattgccat cagcataact ggaataaaaa ttttattttt
     3421 caacctgtta gattcaatat tggctttcat ttcatctaag gatggcaagg ttccgatacg
     3481 gacttgctta aacaatgtta acagcgataa taggattaca ataataccaa tactcatatt
     3541 tggcatatag gaaccaccta taaacgtaat agacaataga gtccaaaatg cagatgtccc
     3601 aagtcgaact gggtttgttt tatctttata actacaatag gctgtatgga gaaattgaca
     3661 accaatcaca atataggtca actctaatag ttgctttgcc aactctgtca tttttgttct
     3721 cctcccctag tcttttttga tatcaatttt ttatcaaata aataattgta aatccccact
     3781 acaataagtg ttataacagc aacaataata gatgtagaag caatccctgc ataattgctt
     3841 tcatagccta actgatctaa tgttccccct atcaagagga ctcccccagc acctacaaac
     3901 gtattttgag caaagaaatt tccaaaattt tcattcgcag ccgcacgcgc ttttattgtc
     3961 tcatcttcaa cctctgttaa ctttctacct aattgagact ctgcagctgc ttctcccata
     4021 ggttgaacca aaggtctgac aaactgaggg tgtcctccta gacgaattga aaagaaacca
     4081 gctaactctc gaataaagaa ataaactgta tagaagtttc caactgtcag acctttaatc
     4141 tttcgaatca aatcgattga tcgttgcttg agtccaaagg tttctgacag ccccacaaga
     4201 ggcaaggtaa ccataaaaat cgtgagcact cgctgattgc taaattcttt tcccaaaatc
     4261 tccaaaaatt caacgagaga aacacctgaa actaaagctg taaccaaacc agctaagact
     4321 actgttgcaa ttgtatcaaa ttttaaaata aaacccacaa caatgattgc tattcctatt
     4381 aatctaatcc actccatatc aaactccttt atattcaaaa tgacagtatt tttaaaattt
     4441 tatcaagatc aataccattc cttatttaat gtgtttttct agttcttttt ggtatttgct
     4501 attggattcc aatttttctt tttgccattt tttaaaaacc tcgttatatt cttttgttgt
     4561 aagaatatct ttttgcaatt tcattccttt aaagatatat ggatccccct taataccaac
     4621 ttgtgagtat ggttttgaga atggtactac gttacttaca actggagaac caccagatga
     4681 agctgttggc atcaataatg aactatctgt cgaccaagct tgagctttgg catatttttc
     4741 atatcttttc tctaggtcag tggtctcaga aacagcatct tctaacaatt tcttatattt
     4801 atccaaacca ggtttagcta caacatcctt atcttttcct ttcgtaatac caaggtgttt
     4861 catggcagaa ccagattttg gatctataat attcaagtaa gacgctggat cttgatagct
     4921 tggagcccat cctgtactat tcaaatcata gtctttttga gaaggagcaa cattgccgca
     4981 tttatcattt tccatcaaac catcaataac atttccaata acgtctgtcg tcgatgttcg
     5041 agtcgctata ctgtagccca atgatgctgg atctactgca tagacataag aaaatgttgt
     5101 cggtgcatct gcttctttat cagtttttcc acaagccact aaaatagctg acgtgctcag
     5161 gaccactcct gctgttaaga gccacttttt ctatttcata aaaaatctcc tttggtttat
     5221 tttaatctac ttttacaatc caaccttctg gcgcttcaat atcgccaaac tgaatacccg
     5281 tcaattcatt atataattta cgcgtcacag gacctacttc tgtttcacta tagaatacat
     5341 ggaaatcatc accatgttga atacctccaa ttggagaaat aaccgctgct gtaccacagg
     5401 cacctgcctc tacaaaacgg tcaagattat caattggaac atcaccctca ataggagtta
     5461 atcccaagcg atgttctgcc aaataaagca aggaatactt ggtaatagat ggcaagatag
     5521 atggactcaa tggtgttaca aattcattat cagctgtaat tccaaagaag ttagctgatc
     5581 cgacttcttc aatctttgta tgagttgatg ggtccagata gataacatct gagaaatgac
     5641 gtgacttggc catttttcct ggtaagagac ttgcagcata gtttccacca accttagccg
     5701 cacctgtacc atttggtgct gcacggtcgt actcatcctg aatcaagaag ttggttggga
     5761 ccaaaccacc tttaaagtaa tttccaactg gcatagcaaa gatggtgaaa atgtattctt
     5821 ctgccggttt taccccgata atatctccga caccaatcaa aagagggcga agatataagg
     5881 ttccacctat tccgtatggt ggtacgtatt cttcattcgc acggacaact gctttacaag
     5941 cttctacaaa catgtctgtc ggaacttgtg gcatcaagag acggtcacat gtacgttgca
     6001 ggcgtttagc attttcatca ggacggaaca gttgaacact gccatcctta gtacgataag
     6061 ctttcaaacc ttcaaatgct tgttgtccat agtgaagact tggagaagac tctgaaatat
     6121 gcaaagttgc atcctctgta agctctcctt gatcccattg tccatttttg aaatgagcaa
     6181 gatagcgata aggtaatttc atataggaaa aaccgaggtt ttcccaatca atcgttactg
     6241 tcatattcca ctccttattc taaaaaccta tttcttatat tctacactat ttttctaaaa
     6301 tagcaagtat attttgtaat tttcagaaaa tttctccaat aaaaaccagc tcttagaact
     6361 gattcttcat ttcacttatt tatcttcagt aactacttcc tgaagataag cgtcaaaaac
     6421 ttcttcatct gaaatcgtgt cagaaatgaa gcttccattg ctagtgcgtt ctgacaagtt
     6481 caagtcttgc aatcggcttt catagattgt tcctttattg gattggacaa gcagagtttg
     6541 gtcgttcaca tccacttccg tactgaagaa atcgccaaca aatccttgct ctgcaactgc
     6601 tcctgccaag aagacacgat gcggtttgtt tttcaactca cgcaagactt gtaatcctcg
     6661 tttggcacgg ctggttgcta gaatttcctc aatggaaaca cgtttcaagc ttccacgctg
     6721 ggtcaagagg tagaaggacg aagtattaca gataaagcca gattggagga catcatcttc
     6781 tttcaaattc atagccttga cacctgctgc cttagcaccg acaaccggaa cctcttcgat
     6841 attgaaacgc agggcataac cattttgact aaccaagaca acatcatcta gtttaatcgg
     6901 agccactgct acaatctgat ctgtatcgtc tttgagctta gcatacttga cagacttaga
     6961 tctataggtc cgccatggag taaattcttt tcgctctacc cgtttgattt gaccaaggcg
     7021 agtcgctgca aagtaggttg tcgcatcgtc aaactgatcc agtacttcca cataaagaat
     7081 ttcttcattc gtttcaaagt ttgtgatggt ttggctcaga tgctctccga tgtccttcca
     7141 acgaatatct gccaactcat ggattggtct gtagatgaca tttccaagac ttgtgaacat
     7201 caagaggtgc tgggttgtct tggcagattg aacaaaaatc aaacggtcat catcacgctt
     7261 gccaatttct tccaaggtgg aagccgcaaa ggaacgtgga ctggtacgct tgatgtaacc
     7321 tgccttggtc acgctgacgt aggtatcttc ctcagcgata agactagctg tatcaatctc
     7381 aattgctttc gcagtatctt ctaaagaact caaacgagga gttgcaaatt tcttcttgac
     7441 ctcacgaagt tctttcttca tgagattgta catagtcctt tcatcaccga taatagccgc
     7501 cagcatagca atcttctcac gaagctctgc ttcttcttcc tgcaagacaa ccacatcggt
     7561 attggtcaaa cggtacagtt gcaaagttac gatagcctca gcctgttctt ccgtaaaatc
     7621 atagctaact ttgaggtttt ccttggcgtc cgccttattc tcagaagcac ggataagagc
     7681 aatgacttca tccaaaatcg aaatcacacg aatcaaacct tcgacgatat ggagacgttt
     7741 ctcagccttt tctttgtcaa agcgtgaacg cgccaaaatc acttctcgac ggtgagcgat
     7801 gtagctagac aggattggaa caatcccaac ctgacgaggt gtgaaattgt caatcgccac
     7861 catattaaag ttgtagttga tttgtaggtc ggtgtactta aataagtagt tgagaacaag
     7921 ctcagtatta gcgtctttct taagttcgat agcgatacga agaccatcac ggtcagactc
     7981 atcacgaacc tcagcaatcc cagctacctt gttattaaca cgaacatcat cgattttctt
     8041 gactagattg gccttattga tttcataagg aatctcagta ataacgattt gttccttacc
     8101 accttttagc ttttcaattt cagtcttgga acgaacaacc acgcgccctt tcccagtctc
     8161 ataagctttc ttgatttcat cacgaccctg aataatagcc cctgtaggga agtctggtcc
     8221 aggcaagaat tccatgagtt tatcaatctt tgcagttggg tggtcaatca tgtaaactgc
     8281 agcatctatg acctcagcta aattatgggg aggaatgtct gtggcataac cagccgaaat
     8341 cccagtcgaa ccattgacca agaggtttgg aaaggctgct ggcaagaccg ttggttcttt
     8401 ctccgtatcg tcaaagttcc atgcaaaagg aactgtattt ttctcgatat cctgaagaag
     8461 gtagcctgca atttcagaca aacgtgcctc agtataacgc atagccgcag gaggatctcc
     8521 gtccatagaa ccgttattac cgtgcatttc aactagaatc tcacgatttt tccagttctg
     8581 tgacatacga accatggcat catagataga agaatccccg tgtgggtgga aattccccat
     8641 gatgttcccg actgacttgg ccgacttacg gtagctcttg tcaaaagtat tgctatcctt
     8701 attcatagaa taaagaatac ggcgctgaac cggcttcaac ccatcacgaa tatctggcaa
     8761 agcccggtct tgaataatgt acttggagta gcgaccaaag cgctctccca tgatgtcctc
     8821 cagggacatg ttttgaatgt tagacataag atacaaagcc cataaaatac caagtgaaaa
     8881 tagaaaattc ttgaagtaag caaactcaca agagaattta tctttttcac acagtatcta
     8941 gggcgtgttc aactcctttc aaagaatgta gagtaggttt ttatgcagta aaagatattt
     9001 tacgggaatt cgtcccgtgt tcagttacga taagtaacca aactatcctg tttgtatttt
     9061 tcaatatgaa aatctggttt tccaaaatta gtcttagttt gtgtcttagc cgctccctta
     9121 aacgcctctt tgagataagc actcatagaa gattcttcat taataatcct gcaatttttt
     9181 caaaccaaga ttttcaaact gcttttttac atagtcattc acatccgact ctaatttcca
     9241 gtttactaac atattatttt ctttcattaa aacactgtcg cttcttctag cgtaaacttg
     9301 acattatctt caatccattt acggcgtggt tctaccttat ctcccatgag aacattgacg
     9361 cggcgttcgg cgcgcgctaa atcttcaatt gtgacacgga tgagggtacg tgtttctggg
     9421 ttcatggttg tttcccagag ctggtccgca ttcatctcac caagtccttt gtatcgttgg
     9481 agggtagcgc ctttaccgaa ctgtttacgg agttcttcta gttctccgtc cgtccaagcg
     9541 taggccactt cttctttctt gcctttacct ttggacatct tgtaaagagg tgggagggca
     9601 atatagacat gacctgcctc gactagcgga cgcatgtaac ggtagaaaaa tgtcaagagc
     9661 aaggtctgga tatgggcacc gtcggtatcc gcatcggtca tgataatgat cttatcatag
     9721 ttggcatctt caatagagaa gtctgctcca acacccgcac caatggtata aatcatggta
     9781 ttgatctctt catttttgag gatatccgcc atcttggcct tggctgtatt gacaacctta
     9841 ccacgaagag gtagaatagc ctggaacttg cggtcacgac cttgtttggc agaaccaccg
     9901 gcagagtccc cctcaactag atagagttca ttcttagcag gattcttaga ttgggctggg
     9961 gtcaatttcc cagacaacaa gcccttatct ttcttgtttt tcttcccatt tcggctctca
    10021 tcacgcgcct tacgtgctgc ttcacgagca tcacgggcct tgatagcctt gcggatgagg
    10081 ttagaagcta attccccatt ttccataagg aaaaaggtca acttatcagc cactattcca
    10141 tccacaactg ggcgagctag ggggcttcct agtttatcct tggtctgtcc ttcaaactgc
    10201 aagtgttctt caggaactaa gatagaaaga acggccgcta gtccctcacg atagtctgaa
    10261 ccttcaaggt ttttatcttt ttccttgaga agacctgttt tacgtgcata gtcattcatg
    10321 accttggtaa tggcagactt gagtcctgtc tcgtgcgttc caccgtcctt ggtgcgaacg
    10381 ttattgacaa aggatagaat gttatctgag aatccgtcat tgtactggag ggctacttcc
    10441 acttgaaaac cattgtcttc cccttcaaag taaagaactg gcgtcaagat ttccttatct
    10501 tcgttgagat aagaaacaaa atcttgtact ccattctcat agtggaactc aatcgcttca
    10561 tctgttcgct tgtccgttaa agacaaggtc acatttttca agagaaaggc tgattcatta
    10621 aggcgctctg aaatggtatt gtacttgaaa tctgtcgtag aaaagatagt cgcgtcaggc
    10681 ataaaagtaa ctttggtgcc tgttttagac ttgggtgctg taccgatttt cttcaaagtc
    10741 gtgacaggtt ttccaccatt ttcgaaacgt tgcttgtaaa ctgcgccatc acgggtaatt
    10801 tcaacttcta accagctaga aagggcgtta acaacggaag aacccactcc gtgaagtcca
    10861 cctgatgtct tatagccacc ttgaccgaat ttccctccgg catgaagaat ggtaaagata
    10921 acctcaacag ttggaattcc catagcgtgc atacctgtcg gcatcccacg tccatggtct
    10981 tgaaccgtta gactaccgtc tttattgata gttacatcga tacgatcacc aaacccagac
    11041 aaggcttcat cgactgcatt atcaacgatt tcccaaacta ggtgatgaag accagcgcca
    11101 tcggtcgatc caatatacat ccccggacgt tttcggaccg catccaaccc ttctagcacc
    11161 tgaatagcat catcattata attgttaata ttgatttcct tttttgacac aaggaacctc
    11221 ctattcgttc atctttacta ttctacaggt tttccaagga ttttgcaaaa tttttctttc
    11281 tccgatgtga caatttcagc agagattctc tgcttttctt tcccaattca tgatataata
    11341 ggagtatgat tacaatagtt ttattaatcc tagcctatct gctgggttcg attccatctg
    11401 gtctctggat tggacaagta ttctttcaaa tcaatctacg cgagcatggt tctggtaaca
    11461 ctggaacgac caataccttc cgcattttag gtaagaaagc tggtatggca acctttgtga
    11521 ttgacttttt caaaggaacc ctagcaacgc tgcttccgat tatttttcat ctacaaggcg
    11581 tttctcctct catctttgga cttttggctg ttatcggcca taccttccct atctttgcag
    11641 gatttaaagg tggtaaggct gtcgcaacca gtgctggagt gattttcgga tttgcgccta
    11701 tcttctgtct ctaccttgcg attatcttct ttggagctct ctatcttggc agtatgattt
    11761 cactgtctag tgtcacagca tcgatcgcgg ctgttatcgg ggttctgctc tttccacttt
    11821 ttggttttat cctgagtaac tatgactctc tcttcatcgc tattatctta gcacttgcta
    11881 gtttgattat cattcgtcat aaggacaata tagctcgtat caaaaataaa actgaaaatt
    11941 tggtcccttg gggattgaac ctaactcatc aagatcctaa aaaataggct ctttgtcaac
    12001 tgtagtgggt tgaaaaaaag ctaagct
//
LOCUS       DBEJZV010000051         9963 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.51, whole genome shotgun sequence.
ACCESSION   DBEJZV010000051 DBEJZV010000000
VERSION     DBEJZV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.51"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="ACL3S0_001938"
     CDS             complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="ACL3S0_001938"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGR1312796.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1995..2927)
                     /locus_tag="ACL3S0_001939"
     CDS             complement(1995..2927)
                     /locus_tag="ACL3S0_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGR1312797.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2924..3781)
                     /locus_tag="ACL3S0_001940"
     CDS             complement(2924..3781)
                     /locus_tag="ACL3S0_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR1312798.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDENKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3785..5131)
                     /locus_tag="ACL3S0_001941"
     CDS             complement(3785..5131)
                     /locus_tag="ACL3S0_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR1312799.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5144..5428)
                     /locus_tag="ACL3S0_001942"
     CDS             complement(5144..5428)
                     /locus_tag="ACL3S0_001942"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1312800.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5432..7462)
                     /locus_tag="ACL3S0_001943"
     CDS             complement(5432..7462)
                     /locus_tag="ACL3S0_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR1312801.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            7653..8660
                     /locus_tag="ACL3S0_001944"
     CDS             7653..8660
                     /locus_tag="ACL3S0_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR1312802.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALKRLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8663..8863
                     /locus_tag="ACL3S0_001945"
     CDS             8663..8863
                     /locus_tag="ACL3S0_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR1312803.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9015..9197
                     /gene="rpmF"
                     /locus_tag="ACL3S0_001946"
     CDS             9015..9197
                     /gene="rpmF"
                     /locus_tag="ACL3S0_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGR1312804.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            9213..9362
                     /gene="rpmG"
                     /locus_tag="ACL3S0_001947"
     CDS             9213..9362
                     /gene="rpmG"
                     /locus_tag="ACL3S0_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR1312805.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9854..>9963)
                     /locus_tag="ACL3S0_001948"
     CDS             complement(9854..>9963)
                     /locus_tag="ACL3S0_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR1312806.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         3230 a         2112 c         1609 g         3012 t
ORIGIN      
        1 aaccatacct acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt
       61 attttttacc tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg
      121 atacgatgtg ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt
      181 ctgccttgcg tttttcaagt tcttcttcgg atacggccat ggaaatttct ttggtatctt
      241 ggtcaaccgt aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt
      301 caggagcgat atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca
      361 agagggccac cttatctccc tgacctttac caacaatcat tgaagaaagt gacagcatct
      421 caggcatacc aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa
      481 cgatttcatc tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg
      541 gcccaacgtg acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa
      601 ggttcccgtt caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga
      661 taactttttg gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac
      721 cagtacatgt gatgcgatct ccgtgaagga aaccatttgc caacaaatac ttcataaccg
      781 cagggacacc accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt
      841 cggccaagtg aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat
      901 ttgcggcatg ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca
      961 tcgttacagt gatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac
     1021 caagttccaa catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag
     1081 ctgattcagc tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag
     1141 ttgccatggt attagcagta tacataccac cacaaccacc agggccaggg caggcattac
     1201 attcaagacg tttcacgtcc tcagctgtca tatcaccgtg gttccatttt ccgatacctt
     1261 caaagacaga aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac
     1321 cataggcgaa aatggctggg atatccatat tagcaatagc aatcatagat ccaggcatgt
     1381 tcttgtcaca gccaccgata gcgacgaagg catccacgtt gtgaccactc atagccgcct
     1441 cgatggagtc cgcgatgatg tcacgagatg ttagagagaa acgcatacca ggtgttccca
     1501 tagcgatccc gtccgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt
     1561 tgacaccttc tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt
     1621 ccgcccaagt cgaaatcact cccacaatcg gtgtttcaaa gtccttatct gtcataccag
     1681 tcgcacgaag catagcacgg ttaggtgatt taaccatgct gtcatagatg ctactgcggt
     1741 gacgtttatc taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca
     1801 atttaaaggc aatgaacaga ataaaattct tgaattttca gaaaattcta tacgcatgtg
     1861 aaatatttaa aattaaaaac aacaaagcgg attagtgcac tttctgatga ccagaatatg
     1921 ctttttaatc cgctttcttt aaataacgta atgtaatttt tacagaaatt ctttcagata
     1981 agtgtattta acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat
     2041 tcactcaaac catactcatt aagaagataa tccattttcc ctacttgacc gaatctttct
     2101 tgaaccccca tccgatgaat ttttgttatt ccatcatcag agaataattc acataaagca
     2161 ctgccaattc cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac
     2221 attgttttta tctgttctgg tatcggtttg attctaaata aatctatcac acctactgag
     2281 taacctaatt tagacagttc atctgcaact cgaatacttg gagcaaccat tataccagaa
     2341 gcaacgatta caagatcttc cccgtgtctt aactcaatgt agcctttaga aaaatcttct
     2401 ccaccttgat acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt
     2461 aagtctaatg tctggttcaa tatttcacga aattgaatat catcagttgc ttcaaaaatg
     2521 atcgatttag gaattaaacg taacaatcca atttcttcaa atggcatatg tgtcccacca
     2581 ttcatttctg cagttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat
     2641 ccaagagaaa taaataattg atcaaatact cttcgtgaag caaaaggacc aaatgtatga
     2701 agataaggtc taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc
     2761 ataatcccaa cattcacata acggtctcca aagtcctttt caagattatg agtagccatc
     2821 gaacttgaca aatcggcttc taagactact atatcagaat cactttgatt agcctctaaa
     2881 aggaagtctc tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca
     2941 attcctgact taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc
     3001 gaagatgatg attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat
     3061 ctaatacaat gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat
     3121 aaatttctct aatatctgaa cccttgaccc taatggattc aaatccaaat gctgaaaatt
     3181 tttctacgaa atcacctgga ttacaaatat cctttgtaaa accatctaat tgttttttgt
     3241 tctcatcaac aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct
     3301 cccaacattg tccttcattt aactcaccat ctccaacaat agcataagta taaaagggac
     3361 tctttcttat tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag
     3421 agcccgttgt catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg
     3481 ttccatttgt atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg
     3541 tactgtatag agctggtcct ccatgacctt ttgataatat gaaataatct ctatctcgtg
     3601 ctgcaaatat ttctggagtc attggcatta tttcaccata aagcactgct aaaacttcta
     3661 cgatagacag acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat
     3721 ttaatcggat gttagtcgca aattttctta actcatcttc tctattttta cttaaaatca
     3781 tcccttattc ctcctttgca gatggctttt taataaagga tactccaaac ataactgcta
     3841 aaataagaac aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta
     3901 aaataattcc tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccgagtc
     3961 ctcccaaaac tggcattaaa aagactggga gaaaactgat taaaatacct tgtaaaaatg
     4021 ctccaatagt ggctccacga acaccaccag atgcattccc aataacacct gcagtcgctc
     4081 cacagaagaa atgaggcaca acgcctggta agataacaac cgttcctgaa gcaatcataa
     4141 ttgccatact tactaaacca ccaataaaac tagagataaa tccaattaga actgcattag
     4201 gtgcataagt ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct
     4261 ctgaaatacc tttaaaggct ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa
     4321 taacaaatac ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg
     4381 taccactact gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt
     4441 aaataactgc catagataaa gtgatactaa cagtactatc acgtaaaaaa gctaaactct
     4501 ttggaaattt aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac
     4561 cactcaacca atatcccaaa gaactgaaat gacctaaagc caccttgtca tttccagtta
     4621 attgaaccat atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta
     4681 atcctcctag taagatgaga ggcaagctag taaagccagc aactgataaa atgaccgcaa
     4741 tcatacatgc catatataga gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa
     4801 aacgagcgat taagatattg aacaccattc ctgcaaacat aatcattgca gtagctgagc
     4861 catatgttgt taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat
     4921 gaaaagcatg ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac
     4981 caccagatac aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta
     5041 atttcttctt ctgaagaact aatcctaaaa ttgcaattaa agctactaaa atagctggtg
     5101 tactaacaat atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt
     5161 cttcacaaag tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga
     5221 tacgaacatc tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat
     5281 cagctgcatt tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat
     5341 tcaaatcact caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg
     5401 aaccacaagc tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa
     5461 tatcattata gttttttgat gatattaaag tttgaacatg atttttatct cttaaaattg
     5521 ttgttaaatg tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca
     5581 acaatcttac ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca
     5641 ttgacattcc tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct
     5701 tccctaaatt aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt
     5761 tctcagttat cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc
     5821 atcctaattt ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg
     5881 gtacaatttc ctttctatca tttttttggt aaagataatt ctttaacgcc aatcttaatt
     5941 ccaattcttg tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa
     6001 aatctccata ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt
     6061 gctcttcagt catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg
     6121 tagaaaaaac catatcatag tcactactag ctttcacctg taaatcatca atctttgagg
     6181 ttcctataaa ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag
     6241 aactaacacc attaggacaa atgattgctg ctttatacca tttttgaggc aaagtatctg
     6301 ctttctttaa ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg
     6361 gattgtcaat agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag
     6421 gataatgttc tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc
     6481 tatagtaagc cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa
     6541 aatgtaacaa agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt
     6601 aaaccggagc aacatctact tcaccttcaa agcaacttga taataaaacg gtgatatagc
     6661 gataatcatc ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata
     6721 aaatagtggt tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt
     6781 caacatccct ttgataccta cacagaatga atactaaacc gaaaaggtaa acttttaatt
     6841 gattaacaat aggtactagc tgtagcttct cataataatc tttaactacc tgatcaatca
     6901 aatcataagt taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta
     6961 tggaggattc cagcaactca ctaaccattt gaaaagctaa gcggtgctta ttccactctg
     7021 aaccgtgtaa agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca
     7081 taatctttct taatgattga atatcagata aggttgtatt cttacttact ttcaaaaagt
     7141 cttggtaatg actattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag
     7201 ctaagcgagt cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact
     7261 gcttcgtacg atttgataaa ctatagcgac cttgcttttt atccagcact atccctttat
     7321 tagctagata aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca
     7381 ccttaacaga taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa
     7441 ctagtgctct ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaaatt
     7501 ataagaataa aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg
     7561 ctgaaacttt ttagtgatta ttttcaactt tctattgact tttaaaaaca aagtgatatc
     7621 atttagatat caaataatgg gaggtcattc ttatgactga aaaactaatc aattcaaaac
     7681 caaatggtgt attcgcattg attctcattg agttgacaat cgtacttggt atctttatat
     7741 ttataatggg ggttggttcg gaaaacattt ttggaattat tatcggacct ttactaatcg
     7801 taattgcagg tctagctcat gctggtttaa aagttgtcaa acctcaggaa gctctggttc
     7861 tgacactctt tggtaattat acaggtacca tcaaagaacc tggtttttac tttgtcaatc
     7921 ccttcagcgt agcagtcaac cctgcaaacc acactcgact tggacaaagt ggtgatgtta
     7981 gcacaaaatc tcctttttta ggagctaaat catcaaatga caatgatgta aatcttgaaa
     8041 ttggcaagaa acacatttcc ctcaaagtca tgaccttgag caattctcgt caaaaaatca
     8101 atgattgctt aggaaaccct gtagaaatcg gtatcgcggt aacttggaga gttgtcgata
     8161 ccgctaaggc agtcttcaac gttgataact acaaagaata tctttcactg caatgtgata
     8221 gcgccctccg taatattgtc cgcatctatc cttacgatgt gtctcctaat gtggatacta
     8281 cgggtgacgg gcaagcagat gaaggtagtc tccgtggctc tagcgaaatt gttgctaacc
     8341 gtattcgtga agaaatccaa agtcgtgttg aggatgctgg cttggaaatc cttgaagcac
     8401 gtatcactta cctagcttat gctccagaaa ttgctgccgt tatgcttcaa cgccaacaag
     8461 catctgccat tattgatgca cggaagatga ttgtagatgg tgctgtagga atggttgaaa
     8521 tggcactaaa acggctcaat gaaggggaat tggtagaact tgacgaagaa cgaaaagctg
     8581 ccatggtttc aaatctcctt gtcgttcttt gtggcaatca tgatgcacaa ccaattgtca
     8641 acacaggaag tctttactaa agatggctga agctaaaaaa aagcagatcc cccttcgact
     8701 ctcaacaaag ttatacgctg cactcgcatc atgggcagaa gacgactttc gttcagtcaa
     8761 tgggcaaatc gaatatctcc tcacagagtg tgtcaagcaa cggaagaaag acggaaaata
     8821 cgtatcagaa accattgacg aaccatttga gattgatatt taacaccttc tcctgtctgc
     8881 cgtgtcggat aggagaattt tttcatcttt ttttgtcaag taactttact ttacaaaaaa
     8941 aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt gaatcgaata taaataccta
     9001 aaggagaaat caaaatggca gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac
     9061 gtcgtacaca ctacaaagta acagctccat ctgtaaactt tgacgaaact actggagatt
     9121 actcacgttc tcaccgtgta tcacttaaag gatactacaa aggacgtaaa atcactaaag
     9181 ctgcatcagc tgaataatag aagggagata ccatgcgcgt aaatattaca cttgaacaca
     9241 aagaatctgg tgaacgcttg taccttactt ctaaaaacaa acgtaacact ccagaccgcc
     9301 ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt tgtgtttaca gaagttaagt
     9361 aagcattcaa tacgaatcaa tacagaagaa aaacgcttga tcagcgtttt ttctttttgt
     9421 taatttcact atattgcaag ggaaatcatt cgaatgacta catttttcac tacctttttt
     9481 gaaataagaa tacggattcg gacgattaaa agtaagagaa actcaaatgt aagttggggt
     9541 tccttttttg tatatttttc aaataacgcc tctacactat ttgtagcaaa ttcaccaact
     9601 acagttgtat cttagttaaa ataagttaga atatgtaagt gagtaccaga tataccaaga
     9661 catcgtcacc atctaaggta tattcaaaat acaaaagttg accaactaga tttctgaata
     9721 tccttatata tccattctta aaattggttt aaatagcgta gtcttttaaa ctagttttga
     9781 gaatccaaaa aatcttccta catatgtaag aagatttttt agttcagaat gattagattt
     9841 agctaatgga tacctatcct acccactcac cgttagcatt gactcgatag ccatcgggtg
     9901 tagtcgtgtt tactaataaa tctcctgaat tataggtata gtaccattta ccagaaactg
     9961 taa
//
LOCUS       DBEJZV010000052         9807 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.52, whole genome shotgun sequence.
ACCESSION   DBEJZV010000052 DBEJZV010000000
VERSION     DBEJZV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.52"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..496
                     /locus_tag="ACL3S0_001949"
     CDS             <1..496
                     /locus_tag="ACL3S0_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HGR1312807.1"
                     /translation="KETSKVRPYFIGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPR
                     PFPETGMLDFQDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKV
                     HFAEFPNLIIWSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFE
                     IEVL"
     gene            653..1078
                     /gene="lacA"
                     /locus_tag="ACL3S0_001950"
     CDS             653..1078
                     /gene="lacA"
                     /locus_tag="ACL3S0_001950"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGR1312808.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1109..1624
                     /gene="lacB"
                     /locus_tag="ACL3S0_001951"
     CDS             1109..1624
                     /gene="lacB"
                     /locus_tag="ACL3S0_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGR1312809.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1635..2564
                     /locus_tag="ACL3S0_001952"
     CDS             1635..2564
                     /locus_tag="ACL3S0_001952"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGR1312810.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            2566..3546
                     /gene="lacD"
                     /locus_tag="ACL3S0_001953"
     CDS             2566..3546
                     /gene="lacD"
                     /locus_tag="ACL3S0_001953"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGR1312811.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3780..4616
                     /locus_tag="ACL3S0_001954"
     CDS             3780..4616
                     /locus_tag="ACL3S0_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGR1312812.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLITENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4652..4969
                     /locus_tag="ACL3S0_001955"
     CDS             4652..4969
                     /locus_tag="ACL3S0_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR1312813.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            4971..6665
                     /locus_tag="ACL3S0_001956"
     CDS             4971..6665
                     /locus_tag="ACL3S0_001956"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR1312814.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFNLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            6880..8286
                     /gene="lacG"
                     /locus_tag="ACL3S0_001957"
     CDS             6880..8286
                     /gene="lacG"
                     /locus_tag="ACL3S0_001957"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR1312815.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGHYSEKTLAGVEAILAANGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDVIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8329..8586
                     /locus_tag="ACL3S0_001958"
     CDS             8329..8586
                     /locus_tag="ACL3S0_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGR1312816.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(8864..9625)
                     /locus_tag="ACL3S0_001959"
     CDS             complement(8864..9625)
                     /locus_tag="ACL3S0_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR1312817.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
BASE COUNT         3133 a         1661 c         1980 g         3033 t
ORIGIN      
        1 taaagaaact agcaaggtca ggccttactt tattggtgga catccaggat ttaattgtcc
       61 tctacttgat gatgaagtct atgaagatta ttatctagag tttgagaaag aagagacttg
      121 ctctgttcca cgtcctttcc cagaaacagg tatgttggat ttccaagata gaagtccatg
      181 gctagaggga caaaaagaaa tagatcttag ttatgatctt ttcagcaaag atgcagtgac
      241 tttggatgaa ttgcaatctc gaacaattgc ccttcgttct cttaaacatg ataggggatt
      301 gaaagtgcat tttgcagaat ttccaaacct catcatctgg tcaactttga acaagggacc
      361 tttcattacc tttgaaccat ggtctggctt gtcaacattc cttgaagaag gagatcattt
      421 agaagataag aagaatgttt gtctcttaga agccaatcag gttgaagaat tagggtttga
      481 gatagaagtt ttataaaaaa gtaaaaaata aataacaaaa acaaacacaa actgttgact
      541 tcttcaaaca atagtagtat attatgtttg tgaggactaa ttgactgttt tttaaagaca
      601 gccaatacac tgctggaatc cagcatagaa aaaataaaaa ggagtataca atatgtctat
      661 tgttatcggt gcagatgctg caggtttgag attgaaagaa gttgtgaaag acttcttaga
      721 aaaagaaaac ttccaccttg tggatgttac agctgaaggt caagactttg ttgatgtgac
      781 tctcgctgtt gctgcagaag taaacaaaga agaacaaaac cttggtatcg tgattgatgc
      841 ttatggagct ggtccattta tggttgcaac taagatcaaa ggaatggttg ctgcagaagt
      901 ttctgatgaa cgttcagctt atatgactcg tggccacaac aactcacgta tgatcactat
      961 gggtgcacaa cttgttggtg atgaattggc taaaaacatc gctaaaggat ttgttaatgg
     1021 taaatacgac ggtggtcgtc accaaatccg ggttgacatg ttgaacaaaa tgggctaatt
     1081 agattatagt aagaaaggta agttaaaaat gagaattgca attggatgtg accacatcgt
     1141 aacagatgaa aaaatggcgg tttcagaatt tttgaaatca aaaggatatg aagtcattga
     1201 ctttggtaca tatgaccata cacggactca ctacccaatc tttggtaaaa aagtagggga
     1261 agctgtaact agcggtcaag ctgatcttgg agtatgtatc tgtggtactg gtgttggtat
     1321 caacaacgct gtaaataaag ttccaggtgt tcgttctgcc ttggttcgtg atatgacaac
     1381 agccctttat gctaaagaac aattgaacgc taacgttatt ggttttggtg gtaaaattac
     1441 tggtgaattg cttatgtgtg atatcatcga agctttcatc catgctgaat acaaaccaac
     1501 tgaagaaaac aaaaaattga ttgcgaaaat tgaacatgtt gaaagtcaca atgctcaaca
     1561 aacagacgca aacttcttta cagaattcct tgagaaatgg gatcgtggag aataccacga
     1621 ctaagaggtg acctatgatt ttaacagtca caatgaaccc atccatcgat atttcctatc
     1681 ccttggatga gttgaagatt gatactgtca atcgtgtggt ggatgtaacc aaaacggctg
     1741 gtggtaaggg actcaatgtt acccgagtac tttcagaatt tggcgattct gttcttgcta
     1801 ctggtttagt gggtggcaaa cttggtgagt ttttggttga acatatcgat aatcaagtaa
     1861 agaaagattt cttctcaatt aagggagaaa ctcgtaactg tatcgctatt ctccacggag
     1921 acaaccaaac agaagttctt gaaaaaggtc ctgaagtatt ggaacaggaa ggtcaagagt
     1981 ttttggaaca tttcaaaaaa ctcttggagt cagttgaagt agtggccatc tcaggtagtc
     2041 tgccagctgg ccttccagtt gattactatg cgagcttggt agaacttgct aatcaagctg
     2101 gcaagcctgt agtcttggac tgctcaggtg cagcacttca ggctgttctt gaatcacccc
     2161 ataaaccaac agtcatcaaa ccaaataatg aagaattgtc tcagcttctt ggaagagaag
     2221 tttctgagga tttggatgaa ttaaaagaag tacttcaaga acctttgttt gcagggattg
     2281 aatggattat cgtttcactt ggtgccaacg gtacttttgc caaacatggt gacactttct
     2341 acaaggtaga tattcctaga attcaggtgg taaatcctgt tggatctgga gactctactg
     2401 tggcaggaat ttcttcagga cttcttcaca aagaatcgga tgcagaatta ctcatcaagg
     2461 caaatgtcct tggtatgctc aatgctcaag aaaaaatgac tggtcatgtc aacatggcca
     2521 actatcaagt tctatatgat caattaatag taaaagaggt ataaaatggc tttaacagaa
     2581 caaaaacgtg tacgcttaga aaaactttct gatgaaaatg gtatcatctc agctcttgca
     2641 tttgaccaac gtggtgcttt gaaacgcctc atggctcaac accaaacaga agaaccaact
     2701 gtggcccaaa tggaagaact taaagtcttg gtagcagatg aattgactaa atacgcttca
     2761 tctatgcttc ttgaccctga gtatggactt ccagcaacta aagctcttga tgaaaaagct
     2821 ggccttctcc ttgcttatga aaaaacaggt tatgacacaa caagcacaaa acgcttgcca
     2881 gactgcttgg atgtctggtc tgcaaaacgt attaaagaag aaggtgcaga tgcagttaaa
     2941 ttcttgcttt actatgatgt agatagctca gacgaactca atcaagaaaa acaagcctac
     3001 atcgaacgca tcggttctga gtgtgtggct gaagatatcc cattcttcct tgaaattctt
     3061 gcttacgatg aaaaaattgc ggatgcaggt tctgtagaat acgcgaaagt aaaaccacac
     3121 aaagttatcg gcgctatgaa agtcttttca gacccacgct ttaacattga tgtcttgaaa
     3181 gttgaagttc ctgttaacat taaatatgtt gaaggcttcg ctgaaggtga agtagtttat
     3241 acacgtgaag aagcagcagc cttcttcaaa gcgcaagatg aagcaacgaa cttgccatac
     3301 atctacttga gtgctggtgt atcagctaaa ctcttccaag atactcttgt atttgctcat
     3361 gaatcaggtg caaactttaa cggagttctt tgtggccgtg ctacatgggc aggatcagtt
     3421 gaagcttaca tcaaagatgg tgaagcagca gctcgcgaat ggcttcgcac aactggattt
     3481 gaaaacattg atgagctcaa taaagttctt caaacaacag cgacttcatg gaaagaacgt
     3541 gtgtaagaaa gtcctcctag tttaggaaca tgaatctaaa aaaatttaaa aaaagttgta
     3601 tgtaaaggtt tacaaaataa cttacttgtg ctatacttaa atcacaagtt aatacaaggt
     3661 gagtgttact aagtaatatt aggcatgatc acaggtgaat tagaaatcag ctgattttct
     3721 agttcatttg tggtcatttt ttgtactcat atacctttaa gatataaaag gaggttgaca
     3781 tgtatcgaat tctaaatcca atgaatcaca atgtctcgct tgtcagaaat gataagggag
     3841 aagaggtgat tgtaattggt aaggggattg cattcggaaa gaagaagggg gatttgatta
     3901 ctgaaaatca ggttgagaaa atctttcgga tgaagaccga agagtccaga gaaaacttta
     3961 tggctcttct caaagatgtt ccgcttgatt ttatcacagt gacctatgaa atcattgata
     4021 agctatcaaa gaaatatcat tatccgattc aagagtatct ctatgtaacc ttgacagatc
     4081 atatttactg ttcttatcaa gctctaactc aaggaaggta caaggatagt aatctgccag
     4141 atatttccgc taagtatcct gtcgcttttc aaatcgcaaa tgaagctttt gaaatttacc
     4201 gtcagaagct agcagatcat tttcctgagg acgaaattat tcggattgct tatcatttca
     4261 ttaatgctga aggtgaaaat gaagtggaac ttgtggagtc gattgataag aggaaagaaa
     4321 ttctcaggaa tgttgaagaa gttttaacgg actatgcaat tcaacgaact aaaaagaata
     4381 accatttcta tgatcgcttt atgatccatt tgaattattt cttggattat ttagacagat
     4441 ctagagatga taaccaatca cttctggata tggaagatca tattaaacaa tcctatccaa
     4501 aagccttcga gattggttcc aagatctatg atgtgattac gcaacatacg ggtcttgatt
     4561 tgtataaaag tgaacgagtt tatctagttc tacatatcca acgtttattg tcataaaaat
     4621 ttatttaaaa ctatataagg agaattctat catgaataga gaagaagtaa cattgttagg
     4681 ttttgaaatc gtagcctatg ctggcgatgc tcgttcaaaa ctattggaag ccttgaaggc
     4741 tgctgaagct ggtgattttg aaaaagcgga cgctctggta gaggaagctg gtagctgtat
     4801 tgcagaggct caccacgcgc aaacaagtct attgactaag gaagcttctg gtgaggactt
     4861 agcgtatagt gtgaccatga tgcatggtca agatcacttg atgacaacta tcttgttaaa
     4921 agacctaatg caccatttaa ttgaacttta caagagagga gttaaataaa atggataagt
     4981 taataatttt tattgagaaa ggaaagcctt tctttgaaaa attatcgaga aatatatact
     5041 taagagcgat aaaagatggt tttatttcca gtatgccagc agtattattc tcaagtattt
     5101 ttatactaat agctgctgtg cccaatattt ttgggtttaa atggtctgat gaacagttag
     5161 cttttatttt gaaaccttac aactactcaa tgggaatttt agctctctta gtagctggga
     5221 caactgcaaa atcgttaaca gattcagtta atacacgtag tatggagaaa accaaccaaa
     5281 tcaactacat gtcaactttt ttagcagctg ttgttggatt gttaatactg gcagctgatc
     5341 caattgaagg tggatttgct aatggtcttt taggtactag aggattactt actgcatttt
     5401 tggcagcttt tattacagta aatatctata aagtatgtat taaaaataat gtaaccatta
     5461 gacttcctga agaggttcca ccaaatattg cacaagtttt taaagatgtt attccgtttg
     5521 ccttatctgt tctttcaata tatggattgg atttaattgt tagaaatatt tttggtacaa
     5581 atgtagcaga atctgttggt aaaatattag cccctctatt ttcagctact gatggttata
     5641 tcggtttagc tattgtattt ggtgcttatg ctttcttttg gtttgttgga attcatgggc
     5701 catctgttgt agaaccttta attgtagcta tcagttatgc aaatatagaa gctaatgttc
     5761 agcttgtgca agctggtatg cacgcagata aaattttaaa tccagttact caaacttttg
     5821 ttgtaacaat gggtggtact ggtgcaacac tagtagttcc atttatgttt atgtggttat
     5881 gtaaatcaaa aagaaataga attgtcggac gtgcgtctgt agttcctact ttctttggcg
     5941 taaatgaacc aatcctattt ggtgctccaa ttgttttaaa tcctatcttc tttattccgt
     6001 ttgttactgc tcctattatc aatgtttgga ttatgaaatt ttttgtagat gttctacaaa
     6061 tgaatagttt cagtattatt ttaccttgga caacacctgc tccaattggt attgttatgg
     6121 gaacggcgct ggctccattg tcattcgtct tggctataac tttaatcatt atcgacactt
     6181 taatctatta tccatttgtt aaagtttatg accatcaaat tttagaagaa gaacggaaag
     6241 gaaactcttc atctgaattg aaagaaaaag ttgctgcaaa cttcaacact gcaaaagcgg
     6301 atgctattct tgaaaaagcg ggtgtcgatg cagcacaaaa taccatcact gaagaaacaa
     6361 atgtcctcgt tctctgtgct ggtggaggta caagtggact ccttgcaaat gctttgaata
     6421 aggcagcagc agaatacaat gtccctgtga aagcagcagc aggcggctat ggtgctcacc
     6481 gtgaaatgtt accagagttt aatctagtta tccttgcccc tcaagttgct tcaaactttg
     6541 aagatatgaa ggcagaaaca gataagctcg gtattaaact tgctaagaca gaaggcgctc
     6601 aatacatcaa attaactcgt gatggaaaag gtgccctagc attcgtacaa gagcaattcg
     6661 attaaggcta ggaactgtga aacagtctcc catcgttacg gaaatcgcta tggcgaattt
     6721 cctaatcgcc ttattaattc gtcggtaaaa agatatcgtt tttacctcct catgtcacaa
     6781 ttcagtgact tggtacaaga agtgagatgg agaagcatgg ctcactgact cctctcctct
     6841 cacttttact ttatttaaat caagaaatag gtgaaaaaaa tgacaaaaac acttccaaaa
     6901 gactttattt tcggtggcgc aacagctgct tatcaagcag aaggtgctac acatactgat
     6961 ggaaaaggac cagttgcttg ggataaatat cttgaggata actactggta cactgccgaa
     7021 ccagctagtg atttttacaa tcgatatcca gttgacctca agctagcaga agagtatggt
     7081 gtcaatggta ttcgaatttc tattgcttgg tcacgtattt tcccgactgg ttacggccaa
     7141 gtaaatgcta aaggtgttga gttttatcat aatttatttg cagagtgtca caaacgtcat
     7201 gttgagcctt ttgtaactct tcatcacttt gacacgccag aagctctcca ctcaaatgga
     7261 gacttcttaa accgtgaaaa tatcgaacat tttgtagact acgctgcttt ctgttttgaa
     7321 gaatttccag aagtaaacta ttggacaacc tttaatgaaa ttggaccaat cggtgatggt
     7381 caatatttgg ttgggaaatt ccctccaggt atccagtacg accttgccaa agtctttcaa
     7441 tcacaccaca atatgatggt gtctcatgca cgcgcggtaa aattgtacaa agagaaaggc
     7501 tataaagggg aaattggtgt tgttcacgcc ctgcctacta aatatcctct agatcatgaa
     7561 aatccagcag atgttcgtgc agctgagttg gaagatatta ttcacaacaa atttattttg
     7621 gatgcaacct atctgggtca ctactctgaa aagactctgg caggggtaga ggctatcttg
     7681 gctgccaatg gtggtagctt ggatcttcgt gaagaagatt ttacagcatt agaagctgca
     7741 aaagacttga atgatttcct aggaatcaac tactatatga gtgactggat ggaagccttt
     7801 gatggagaaa ctgaaattat ccataatggt aaaggtgaaa aaggaagctc taagtatcaa
     7861 atcaaaggtg ttggtcgtcg tgtagctcct gactatgtac cacgcacgga ttgggattgg
     7921 attatctacc ctcaaggttt gtatgaccaa atcatgcgcg tgaagaaaga ttatcctaac
     7981 tacaagaaga tttacatcac tgaaaatggt ctcggctata aagatgagtt cgttgataac
     8041 actgtttacg atgatggtcg tattgattac gtgaaacaac acttggagat cttgtctgat
     8101 gtgattgcag atggagctaa tgtaaaaggt tacttcattt ggtcattaat ggatgtcttc
     8161 tcatggtcaa acggttatga gaaacgttat ggtctcttct acgtagattt tgaaactcaa
     8221 gaacgttatc ctaagaaatc agctcactgg tacaagaaag tagcggaaac tcagattata
     8281 gactagtaga attagtcatt agatatagaa ttttagtgag tcaaaaagat gttcaaagat
     8341 tttatccaat ctatttatga aaaagtttat attataaatt tcgaaaaatg ctctcaaata
     8401 ccgtgtttga cgagtgaaga attgaaaagt cttggaaaat ggtatgtctc gactggtaaa
     8461 gaatggattt gtcattcaga tgatgagctg gaagaattta aaaatctatt tttaaatttt
     8521 atcaatcctg aagaatggga tactatctcc tttgattcag attttatgcc gtttcaacaa
     8581 tcgtaaccaa tttctcaaaa aagttaaatc ttatatttag tactctgtaa aactcttatc
     8641 taatcacgtt gcttatactc aatgaaaatc aaagagcaac tttaaactag gaagcgagtc
     8701 gcagatttct caatgcatag ctttgaggaa ttgggcaaaa agtctttgat atagaaaaac
     8761 gcatagtatc aggtgtttca acacctgata ctatgcgttt tattgtggga agatttactt
     8821 ttttcttctg aaattgagtt gttacccagg ctctttcagt ttattaaggc ttgatgactt
     8881 taatgtgttt agatagctta aaaaggattg aatcacttag tttagaatct gaaacaatag
     8941 tatcaagatt tgatacatta taaaaagtat aaaaatcaaa cttattgaac ttgctatgat
     9001 ctgcgagtaa atatttttta ttagaattat ttaaagcgat gcgttgagcc tctccctctt
     9061 cctcgctaaa agtagctaga gctccgtttt gaataccatt acagctaacg aaagctttag
     9121 aaaattggag attagagaga ttttgtaggg tcaatgtacc aacaaaagca cctgtaatat
     9181 cgcgataatt tccacctatt aaaatcaaat ctgttaattt tcgttcgctt aaaatcagaa
     9241 aaacaggtag actgttggtt acgacgcgga tattgtcaat aggcaactca cgcgcaaaaa
     9301 actctaatgt tgttcctggt ccaatgaaaa tagtttctct ttcttctact agactgcctg
     9361 caaaatgggc tatttcttgt ttttctgccg tttggagggc ttgtttttca atatttgatc
     9421 gctcattagt caaaagggag ttggttcgaa gtttttcagc tccaccatgc acacgaatca
     9481 gcaaatcttt atcagctaat tcctgtaaat agcgccttgc agtcatatct gaaacggcta
     9541 tttcgtccat aatctgttta actgttatgg ttcctttact atttactatc tctaaaattt
     9601 tggctaattt ttcttgtttg agcatattat cacctcgttt cctactacta tcttaccata
     9661 aacaaactca tcattcaaat acaaaaacaa caaaataaaa caaaaacaaa aatatcgagg
     9721 tttattttca aaactttcga tatttttatt aagttattat tttgttgttt ctagtttact
     9781 ttttgatggt taagagtggt ggagaat
//
LOCUS       DBEJZV010000053         9793 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.53, whole genome shotgun sequence.
ACCESSION   DBEJZV010000053 DBEJZV010000000
VERSION     DBEJZV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9793
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.53"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            68..741
                     /locus_tag="ACL3S0_001960"
                     /pseudo
     CDS             68..741
                     /locus_tag="ACL3S0_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
     gene            complement(783..2771)
                     /locus_tag="ACL3S0_001961"
     CDS             complement(783..2771)
                     /locus_tag="ACL3S0_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312818.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVIAVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKRGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSDIYNQFYGGMNVSISEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2773..3531)
                     /locus_tag="ACL3S0_001962"
     CDS             complement(2773..3531)
                     /locus_tag="ACL3S0_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312819.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3959..4150
                     /locus_tag="ACL3S0_001963"
     CDS             3959..4150
                     /locus_tag="ACL3S0_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312820.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4504..4776)
                     /locus_tag="ACL3S0_001964"
     CDS             complement(4504..4776)
                     /locus_tag="ACL3S0_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR1312821.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(4835..5284)
                     /locus_tag="ACL3S0_001965"
     CDS             complement(4835..5284)
                     /locus_tag="ACL3S0_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGR1312822.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTKRYRCGLCRGKLLLVNQPED"
     gene            complement(5271..7400)
                     /locus_tag="ACL3S0_001966"
     CDS             complement(5271..7400)
                     /locus_tag="ACL3S0_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGR1312823.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFVTRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            7453..7611
                     /locus_tag="ACL3S0_001967"
     CDS             7453..7611
                     /locus_tag="ACL3S0_001967"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312824.1"
                     /translation="MKIKKQTRKLAAGCSKYCFEVVDKTDEVSSKHCFEVVDRTDEVS
                     NRTTVRRS"
     gene            7725..7856
                     /locus_tag="ACL3S0_001968"
     CDS             7725..7856
                     /locus_tag="ACL3S0_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGR1312825.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
     gene            7857..8762
                     /locus_tag="ACL3S0_001969"
     CDS             7857..8762
                     /locus_tag="ACL3S0_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGR1312826.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            8759..9574
                     /locus_tag="ACL3S0_001970"
     CDS             8759..9574
                     /locus_tag="ACL3S0_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGR1312827.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
BASE COUNT         2893 a         2069 c         1880 g         2951 t
ORIGIN      
        1 tcacccagag aagacttctg gatggctaac ttgaacttga aatttagcgt cagaaacaaa
       61 tcacgaaatt gattcaaatt ttgcaggtcg tttaaatatc ctgcgtgcgg gtgttcttga
      121 tgctaacgat ggaattattt ccattgctgg tgtggttatc ggagttgcca gtgccacgag
      181 caatatctgg attatctttt tatcaggttt tgcggctatc ttagctggtg ccttttcaat
      241 ggctggtgga gaatatgtat ccgtttcaac tccaaaagat accgaggaag ctgccgtttc
      301 gcgagaaaaa ctcttgctag accaagatag ggaactagcc aaaaaatccc tctatgctgc
      361 ttatatccaa aatggagaat gcaaaacttc tgcccaactc ttgaccaata agatctttct
      421 taaaaatcca ctcaaggctc tggtagagga aaaatatggg attgagtatg aagaatttac
      481 caatccttgg cacgctgcca tttctagctt cgttgccttt ttccttagaa gtttgcctcc
      541 aatgctgtca gtgaccatat tcccaagtga atatcgcatc cctgctactg tccttattgt
      601 cggtgtggcc cttcttctca ctggttacac tagtgccaga cttggaaagg atccgactag
      661 aacagctatg attcggaacc tagctatggt ctcttgacta tgggagttac cttcctgctc
      721 gaacaacttt tcagcattta gaatacaaga aatacctcga ttttgaagtc gaggtatctt
      781 ttttacattt gcacaatctt acgataactt cttgaagtaa tcatgaaaat cagcacatag
      841 gcgatgagga agatagcgca gatagacaag gtcacgatca acatcatagt cgtatccagt
      901 acaccaatca cttttaaaat caggctaagc atatggtagg caaaggctag atgtatgaag
      961 gcaaaaagca aaggaaggaa gaaaacagtt aaaacctgtt tgttgatggt ttgcttgatt
     1021 tgcttttgat ctaaaccgac tttctgcaag ataataaagc gttcacggtc ttcatagcct
     1081 tcagaaattt gtttgtagta gatgaccaga acggttccga ccataaagat aatggatagg
     1141 aaaataccaa taaagaagac accgccaaag aggacactca tttgagcact agcatctgct
     1201 agagtgctac catacacata gttaccttca gtgtttaatt gagcattaaa cttttgtaag
     1261 tatttttcat attcttcagc gaccttgagt tgctcttctt cactgatact tacattcata
     1321 ccaccgtaaa actgattata gatatccgaa tctgggaatt gatccaaaaa ggcttgtaaa
     1381 tcaggaacaa caaggtaatt gtaatcagta gtcaagatat taaacttatt tggaacatgg
     1441 ttcacaatga aatctttatt aaattcttct ttgacagaaa attgatgatc atttagagtt
     1501 agagctttct gtcctttcag tccgtcattt ttggcaaaga gaccgacctc atttcctgat
     1561 agagacagtt tttgaccagt catattttca taatcttttt ggtcaaatac catgaaaact
     1621 gttttgggtt ggacacggtt ttgtcctttt tcaaaaatag ttaacttggt tccttcttga
     1681 tttgcaatac caaagttact gtaacgaagt acttctttct ctttgacact ataacctttg
     1741 tcacttgcaa actggctcaa gagtttgtcc aaatcttctt tttcaacatt ttgccctgaa
     1801 accccaaaat catgaggatt tagaactttt ttaaagcttt ctgcggaatt gaaaatgctt
     1861 gtcgctgctg acatggttac caaaaccatt gttgacaaaa tagcgatggt tgctagtcca
     1921 accgcatttt tcttcatacg gaaaatcaag ttggaaacag atatgaggtt attaggttgg
     1981 taatagtatt tcttgttttt ctttaagatt tgtaggaaga ctgtaatccc tgcattaaac
     2041 aagagatagg tcccaaagat aaccagtaaa acagctatga agaaggttgt taaggctgta
     2101 agaggatctt ttaccgtaag ggcaagataa tagccaatcc ctaaacttat ggaaccaaga
     2161 atagtttgga gaggtaggaa acgacctctt ttctctccgc ttgctttctc acgcgagagc
     2221 tggagggcat tcatacgggc gattcgaagg gcattcagga acatgaggcc taggaaaatc
     2281 aatccaaaga caagaagtac tgcaatgaca actttcatct ggaaggtagc aaccagctca
     2341 accttcaatt tcattagttt gagcaggaaa gcgaaaatta acttgtcaaa caaggctcca
     2401 ataccgatac ccgctccaac agttagaatc ccaaatacca ctaactcctt aaaggtcata
     2461 ctgataagat gacgcttctc caagcccaac atgccataaa ttcctagttc cttggaacgg
     2521 ttcttcatga caaaactatt ggcatagaga acgataatgg ctgacgcaag ggtgacgaca
     2581 aacataccaa atccaagtgt agcctgaatg gttgttcctc cacgaatttc agcaatcttg
     2641 ggattgaagg ttagagagta aaagagatag gtgacagtga ctgccaagag aacagctagc
     2701 gcaaaaggat agtagagttt gcggttttta atcaagttcg ataccgctaa cttattagtt
     2761 aatcgaaaca tactaattca cctcgcttgc catgacagtc aaggtatcag agatttcttg
     2821 gaacatctga cgttctgtct tctctccacg gtagatttgg ttgtaaagaa tgccgtcttt
     2881 gataaagaga acacgcttgg ccctgctagc agctgctgtt gagtgggtta ccatgaggat
     2941 ggtttggccg cgctcattga tttcatcaaa gacatcaagt aaggctgcag atgacttgga
     3001 gtcaagagct cctgtcggtt cgtccgcaag gagaatttca ggttcagtga tgatggcgcg
     3061 tgctactgct acacgctgtt tctggccacc agaaatctcg taagggtact tctcttgtaa
     3121 ttggtttatt cccagattct cagctgtcac caccaatttc ttcatcatct ctgtaatagg
     3181 tcttcttgac aagacaagcg gaagcaagat attgtccttt acagatagag tatctagcaa
     3241 gttaaagtct tggaagacaa agcccaactt ttcacgacgg aagctagagg cctgtgaatt
     3301 tttaatggtt gcggtgtcag ttccattcaa gtaaacctga ccacgacttg gtttatccag
     3361 catagctaga atattgagaa gagttgattt accagaacca gactcaccca tgatggcaac
     3421 gtagtcaccc ttttcgacgg taaagtgaat atccttgagg gcctctactt ggttgccctg
     3481 aaaacgagtt ttataaattt tttgaacgtg ttttacatct aaaagtgtca tgagaatctc
     3541 ctttcttaat atcccatcaa atgaaatgtc gcttgcatca tagcgcatcc cagctgaacg
     3601 cgctcgattt ctttgtgact tggttttctt gttttcttat gtaagatttg tttcatgatg
     3661 ttactccttt gttctttatg agtctagttt acatcaaaaa aagacctctt gccataacct
     3721 aaccttacaa aagagacttt aatcttacat ttttgtaaga ttgggggaaa tgtaagcaaa
     3781 attacttaga aaatgatttg atttcctatt tttaaaattg taaaatataa atatgaaaag
     3841 gcttactttg gaaaggagga agcgggaact aacattttag taagcttacc tagataacat
     3901 accattcaat ttaacacttg caagtcgttc aacctataag gaaagaaggt gcgccttaat
     3961 gaaacacaaa gaacatatac tcatcggact tctctatctg ctctctccat tcatcggtca
     4021 gctcttagtt gaacacacac actttatcag tacagaattt accggcactg cttatgttat
     4081 ttgctggtta tcagttgtta tcagcatcca ccatttttcc aaaaatgtat tgtctcaaca
     4141 gcaaaaatag attaaaaaac tgcgtttaaa ttactgcttt tatagtaaaa tgaaataaga
     4201 acaggacaaa tcgatcagga cagtcaaatc gatttctaac aattttttag aagtataggt
     4261 gtcctattct agttccaatc cactatagtt tgtggatgaa gctggcgaaa tattattaat
     4321 actattcaaa aatcaaagtg caaactatat caacttcaca ttgccgacta aattacagcc
     4381 tgcggctggc ttcctagttt gcactttgat ttttattgag tataaaagta aaaaagcttt
     4441 aaatcaagca gtttagacta ttgatttaaa gctttttgcg tattccaaat cttttgtaaa
     4501 acctcaccaa aaccagcctt cattatcgtc aatggcttga gcttctttgc gtttacgtgg
     4561 gcctgttccg tacatttctg cttcgatttc ttccttggtt ggcatgatag aagctaggat
     4621 gatatagata atcaccccaa gtccaaagtt tgcgactgta aaaatggcaa acagaaaacg
     4681 tacaagggta acatcaaagt tccacttgtc tgacagacct gctaaaactc ctgaaatcat
     4741 gcgatttcgt ctcattttat aaaacttact gttcatgata tttcctcttt ctgctaggtt
     4801 agacatagta tatcacggat aggctcggct ttcatcagtc ctcaggctga tttactaata
     4861 gcaactttcc tcgacaaagt ccacagcgat agcgtttggt atcaatccta cgcttacgct
     4921 gataagtttg ctggcaggat tggcaacgat agagcttgat tggcttggag ttactattgg
     4981 gcaaggatgg tacaaaccgt aatccatcca ctgctttcaa cagttcctta aaatcccgat
     5041 ccttgtgttg atagcctttc ccttgaaaat agaggtgata atgacagagt tcatgtcgga
     5101 caattttcct aaaaacgtcc aaccccagtt cctgataaac cttgggatta aaatccaaat
     5161 gcccatcttt ggggaaaaat cgcccacctg tcgaacgtag acgcctattc cactggacat
     5221 gatggataaa aggtctgccg aagtcttcta gtgaaacctg cttgacgtaa tcagtcagtt
     5281 tcatttggag ctaggagaga cagattaact ttttcacgtt cagtatcaat tttcttaacc
     5341 caaacgctca ccaaatctcc aactgccacc acttgactag ggtgtttgat aaacttgcga
     5401 ctcatatggg aaatatggat gagaccgtcc tcatgaattc cgatatcaac aaaagcaccg
     5461 aaatcaacaa cgttacgcac cactccttct agcttttgtc caaccactaa gtccttgata
     5521 tctaggacat cttgacggag aactggagca tcaaaggaat cacggaaatc tcgacctggt
     5581 ttgagaagat ctgcaatgat atctttaaga gtttctggac caaggtctaa ctcttgcgcc
     5641 atttccttga ctgaaagcga cttgagtttg ctttgggcct cttcattcag atccttaatg
     5701 tccaagcatt tgaagagttc cttaacggca gcgtaatttt ctgggtgaac tcctgtatta
     5761 tcaaggatat tgctactttc agggatacgg aggaaaccag cagcctgttc aaaagccttg
     5821 gcccccaaac gaggaacttt cttgatttgg gagcgtgaag tgatttttcc ctcttcctca
     5881 cggtatttga cgatattttc agaaatggtt ttattgagtc cagctacgtg tgaaagaaga
     5941 gctgggctag ctgtattgac attgacacca acttggttaa ccactgtatc gacaacaaag
     6001 tccagactct cagatagttt cttctgactg acatcgtgtt ggtattgacc gacaccaatt
     6061 gacttaggat cgattttgac caattccgca agaggatctt gcaaacgacg ggcgatagaa
     6121 atggcagagc gtttttcaac ggtcaagtct ggaaactcct gacgagcaag ttcgctggca
     6181 gaatagacag aagcaccact ttcattaacg ataacatagc tgacttcagg gaaatctttc
     6241 agaacttccg ctacaaaagc ttcactttca cgactggccg ttccatttcc aatggcaata
     6301 atctctacac cgtattgacc aattaaatct gctaaatctt tcttggcttc ttcgatttga
     6361 cgagctgatg ctggtttaac aggataaata acctgagttg tcagcatttt tcctgttgca
     6421 tccacgacag ctagcttggc acctgtacga aaggctgggt caaacccaag aaccacgcgc
     6481 cctttcagtg gagcaaccaa gaggagattg cgcagattgt cagaaaaaag ttggatagct
     6541 ccctcttcag ctttctcagt taattctgtc cgaatacgac gctcaatagc aggcaagacc
     6601 tttttcttaa cggattgctg aacaacttca tcaatataag catttttcac cttgaaacga
     6661 gtaacaaaga aggcaagaat acggtccgtc gcatgttcaa aaccgatctt caagacacca
     6721 agtttctccc cacgattgag agccaaggta cgatagcctt gcatagttcc aactgtctct
     6781 gaaaaatcat aataaatctg aaaaacctgc ttttcatcaa gactttcatc cttggcttga
     6841 gaagtgagtt tagagtgtct cagcacttcc tgataagtca tagaacgcaa ggtcacatct
     6901 tccgataagg cttcgaccaa aatatcaact gcaccggtca aggcttcctt gccagtcgca
     6961 aatccttcac agacgaactt ttcagcttct ttctctaagt caactatatt ctgcaaaatc
     7021 aagcgagcaa gaggaaagag tccagcttca cgggcaatgg ttgccttggt acgacgcttt
     7081 tccttataag gaagatagag ttcttcaacg tctgctaatt tttcggcaac taagatagct
     7141 tcttccaatt ccttggtcaa cttgccttgc tcttgaatct tagctaagac agcttcctta
     7201 cggtcattga gatttgtcag acttttatcc aaatcaataa tagccttaat cgccacctca
     7261 tccagactac cagtcatgtc cttacgataa cgcgcgataa agggaatagt cgccccttca
     7321 gctgtcaaac ttagaacggt atcaatttgc tttaacgtca ctcccaaatc ctgagagatt
     7381 ttttcatatt ttttatccat aaatctatta taccacaagc tggaaggctt tctccaatcc
     7441 ttttcatact caatgaaaat caaaaagcaa actaggaagc tagccgcagg ctgctcaaaa
     7501 tactgttttg aggttgtgga taagactgac gaagtcagct caaaacactg ttttgaggtt
     7561 gtggatagaa ctgacgaagt cagtaaccgt actacggtaa ggcgaagctg acgtggtttg
     7621 aagagatttt cgaagtgtat caactatcga aaacaaatta aaaaactccc ttttccgcaa
     7681 aataatagta taatagaggt agaatttaga atcgaggtac acctatggct gtcaaattta
     7741 caaaacgaga cgacttggac aagatgtttg aagagtttgc taaactccct gatttgaaac
     7801 aagttacttt ccctgatgac aaagagaaaa aagtcaaagc agaaaagaaa aactagatga
     7861 ctgcttttca acaactccca tctagtgtac ttcaaactgg agccattttt ctctccatta
     7921 tcattgaagc ccttcccttc gttctgatag gaagcattgt ctcagggctg attgaagttt
     7981 atatcacacc tgacaaggtt tatcattttc tccctcgaaa tcgttggggg agaatctttt
     8041 ttgggacctt tgtcggtata cttttccctt cttgtgaatg tggaatcgtc cccatcatca
     8101 atcgttttct ggaaaaaaag gttccaagtt acacggccgt tccttttctt gtgacagcac
     8161 ctgttatcaa tcccattgtt ctttttgcga cctattctgc ctttggcaac tccttccatg
     8221 tcgccctatt acgagctctg ggttccattc ttgtggctgt aatactagga atttttctag
     8281 gatttttctg gcaagaaccg attcagaaag aaaatcgtct ggcttgtcat gagcatgatt
     8341 tttcttactt gagttctgca aaaaaagttt ttcaagtctt tgtgcaggcc attgatgaat
     8401 tttttgatac ggggcgttat ttggtatttg gctgcctctt tgcttctata atacaggtct
     8461 acgttccgac tcggattctg acctctatca gtgcgactcc tctttttgcc atcctgctct
     8521 tgatgctttt ggcctttctt ctttcgctct gtagtgaggc ggatgccttt ataggtgctt
     8581 ctctactctc gagtttcggt ttggctccag ttctggcctt tctcgtcatt ggcccaatgc
     8641 tggatatcaa aaatattctc atgatgaaaa attacttgaa agcacgattt attagtcact
     8701 tcattacgat tgtgactctg gtcgttttag cctattctct cttgattgga gtcatcctat
     8761 gattcgattt ttagttttag ctggctattt tgaactgact atttacctcc atctgtcggg
     8821 caaactaaac cagtacatca acatgcacta ttcctatctg gcctatattt ccatggtgct
     8881 ttcctttatc ttggcaattg ttcaattgta tatctggatg aagcaagtca aaacccacag
     8941 tcatctgaac agccgattgg ccaagatgac gagtatttct cttctggcta ttccacttgt
     9001 catcggctta actttcccaa ctgttagctt ggattctcag actgtttctg ctaaaggtta
     9061 tcatttcccc ctatcggaag gaacggatct agccattcag acaagcgaag ggacgacaag
     9121 ccaatatttg aaaccagata ccagttctta tttttcaaaa tcagcctatg aaaaggaaat
     9181 gcgaacggcg gcggataaat acttatccca agatagtatt cagatcacta atgaaaacta
     9241 tatggaagtc atggaggcta tctacgacta tccagatgag tttgagggca agacaatcca
     9301 gtttacaggc tttgtctata acgaccccag tcatgccaat agtcaatttc tgttccgatt
     9361 cggcattatc cactgtatcg cagattctgg tgtctatgga ttgctgacca agggcaatac
     9421 ccggcagtat gaaaacaaca cttggatttc agccaaagga aaactggtca atcactacca
     9481 taaagaactc aaacaaaacc ttccaacctt ggaaatcgac agctttacca aagtcgataa
     9541 accagaaaat ccctatgtat atagagcttt ttaagaaaat caaaataaaa acgaacaagt
     9601 tctcttctga ataacagaaa aaggctctat aatatttgta gtgggtaaat cccctataga
     9661 tattatggag cttatttttg tgtagaaaaa aagtcccata tgacctataa tgaaaagcga
     9721 tcaaacaact cattagaaag attcatatgg gacaattaca ttttatcaca aaactactcg
     9781 atatcaaaga cac
//
LOCUS       DBEJZV010000054         9559 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.54, whole genome shotgun sequence.
ACCESSION   DBEJZV010000054 DBEJZV010000000
VERSION     DBEJZV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9559
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.54"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..4116
                     /locus_tag="ACL3S0_001971"
     CDS             <1..4116
                     /locus_tag="ACL3S0_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR1312828.1"
                     /translation="KQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGSIVEPEKVE
                     APKEYTGKIEQPSAEDTKPENEASSTNGESERPKDKIKEEKQVDKKLELRNVSNVELY
                     TVENNKYRHITAVDGALDSSLKYFMKVKSENFKDIMLPVTKIESTTKNNKEVYKIVAH
                     AENLIQHENNVISNDYTYYLPKTQQSETGVYTSFKNLVDAMNSDPNGTFHLGATMDAR
                     EVELPDDQESYVKNEFYGKLIGENNGKYYAIYNLKKPLFKTLNTATIQNLSIKEANVS
                     SKEDAATISKEAKYNTLIDNVHSDGIIAGERGIGGLVSKVDNSRISNSSFTGRITNTY
                     DTTVGYEIGGLVGKLSGSLASIEKSIASIDIASNAKSGDQIVGGIAGVVEKSATIKYS
                     YVEGNVNNVRHFGKVGGVAGNLWDRDSQDVSKSGKLSYVLSDVNVTNGNAISGDNFDN
                     MKEDHAYSSKGNKVVNVVQVDDELVTKDSDVQRGTVLDADKVKEKKAELVSKHSTKVE
                     DFDFTSRYTTIYNEVTGYQKSREQVYKNIEKLLPFYNRETIVKYGNLVDESSELFTKE
                     LLSVVPMKNNEVITDINKNKQEINKLLLHFEGNKSQVLNIAYKNDFSKVAEYSIEYQG
                     LLYTPNTLLHDYSNIVDNVLTDLNSVQYDSNAIKKILDISDKVKNTELYLDEQFVKTK
                     ANIKDTLSKLLSADAAIAENSNSIIDNYVIQKIKQNKEALLLGLTYLERWYNFKYGET
                     KAKDLVMYHLDFFGKSNSSALDNVIQLGKSGFNNLLAKNNVITYNVLLSKNYGTESLF
                     KALEGYRKVFLPTTSNNEWFKAQTKAYIVEEKSSIPEVSKKQSEQGTKYSIGIYDRLT
                     SPSWKYQSMVLPLLTLPEEKTVFMIANISTIGFGAYDRYRSKVHPKGDNLNKFVEDNV
                     REAAKRFRDHYDYWYKILEPENREKLYRSLLVYDAFKFGRDNTEDKVTYQADFETDHP
                     AIKYFFGPAGNNVVHNGHGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLG
                     GYGRRSGLGPEFYAKGLLQAPDHPYDPTITINSVLKYDDSENSTRLQVADPTQRFNSA
                     EDLHNYMHNMFDLIYTLEILEGRAVAKLDYNAKNDLLRKIENKYKQDPDGNSVYATNV
                     VRRLTMDEVNKLNSFDSLIENDIITSRGYKDQEYKRNGYYTIDLFSPIYSALSGEKGT
                     PGDLMGRRIAFELLAAKGYKEGMVPYISNQYEKDAKAAGSKIKSYGKEVGLVTDKLVL
                     EKVFNNRYSSWVEFKKAMYNERIAKFNNLISVSFNNPNVSWGRTNRITITSIANLQNM
                     INTAVNEDAEDFRAQLYPDTNSRVLKLKKAIYKAYLDQTNDFRRSIFENKK"
     gene            4160..9559
                     /gene="zmpD"
                     /locus_tag="ACL3S0_001972"
                     /pseudo
     CDS             4160..9559
                     /gene="zmpD"
                     /locus_tag="ACL3S0_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease D"
BASE COUNT         3554 a         1360 c         1906 g         2739 t
ORIGIN      
        1 aaacaggtag caccgcttcc agaatataca ggaccacaag ccagcgctat tgttgaacca
       61 gagcaagtag caccactacc agaatacaca ggggtacaag ccggatcgat agtcgagcca
      121 gagaaagtag aagcaccgaa agaatatact ggtaaaatcg aacaacctag tgcagaagat
      181 actaaacctg aaaatgaggc aagctctaca aatggggaat cggaacgtcc taaagataaa
      241 attaaagaag aaaaacaagt cgacaagaaa ctagaactta gaaatgtttc aaacgtggaa
      301 ttatatacgg tagaaaataa taaatatcga catattacgg ctgtagatgg tgctttagat
      361 agttcattga agtatttcat gaaggtaaaa tcagaaaatt ttaaagatat aatgttgcct
      421 gttactaaaa ttgaaagtac aacaaaaaac aataaagaag tatacaaaat tgtggctcat
      481 gcagaaaatc taattcaaca cgaaaacaat gttatttcga atgactatac atattattta
      541 ccaaaaactc agcaaagtga aactggcgtc tatacatcat ttaaaaattt agttgatgca
      601 atgaatagtg accctaatgg aacattccat ttaggtgcaa ctatggatgc tcgtgaagtt
      661 gaacttccgg atgatcaaga aagttatgta aaaaatgaat tttacggaaa attaataggt
      721 gaaaataatg gtaagtatta tgctatttat aacttgaaaa aacctttatt taaaactcta
      781 aacaccgcta ctattcagaa tctttcaata aaagaagcga atgtttcttc taaagaagat
      841 gctgctacaa tatcgaaaga agcaaaatac aatactctta tagataatgt tcattctgat
      901 ggtattatag ctggtgaacg tggaattggt ggattggttt caaaagtaga taactcgaga
      961 atttctaata gtagttttac aggcagaata actaacacat atgatacaac tgtagggtat
     1021 gaaattggtg gtttagtagg taaactttct ggttcgcttg cttctataga gaaatcaata
     1081 gcatcgattg acatagcctc taatgcaaaa tcaggagatc aaattgttgg tggtatagcc
     1141 ggagttgttg agaaaagtgc gacaattaag tatagctatg ttgaaggaaa tgttaacaat
     1201 gtgcgacact ttggtaaagt tgggggagtt gcaggtaatc tttgggatag agattcacaa
     1261 gatgtaagta aatcaggtaa actatcatat gttttaagtg atgttaatgt aacaaatggt
     1321 aatgctatat cgggtgataa ttttgataat atgaaagaag atcatgctta tagtagtaaa
     1381 ggcaataaag tagtaaatgt agtccaagta gatgatgaac ttgtgactaa agattcagat
     1441 gtacaaagag gtacggtatt agatgctgat aaagtaaaag agaaaaaggc agaattggtt
     1501 tccaaacaca gcactaaagt agaagatttt gattttactt caagatacac tactatttac
     1561 aatgaagtaa caggttatca aaagtcgaga gaacaagtat ataaaaatat tgaaaaacta
     1621 ttaccgttct ataatcgaga gacaattgtt aaatatggta atttagtaga tgaaagcagc
     1681 gagctattta ctaaagaact tctatcagtt gttcctatga agaataatga agtaataact
     1741 gatattaata aaaataaaca agaaataaac aaattgttat tacattttga aggtaataaa
     1801 tcacaagtat taaatattgc atataagaat gatttctcta aagttgctga gtatagtata
     1861 gagtatcaag gattattata tactcccaat actctattgc atgactacag taatattgta
     1921 gataatgttt taactgactt gaattctgta caatatgatt caaatgcaat taagaaaata
     1981 ttagatatct cagataaagt taaaaatacg gaattatact tagatgagca atttgttaaa
     2041 acaaaagcaa atataaaaga tactttatca aaacttctgt cagcggatgc agcaatcgct
     2101 gagaatagta attcgataat tgataattat gttattcaga aaatcaaaca gaataaagaa
     2161 gctttattgt taggattaac atacttagag cgttggtaca attttaaata tggtgaaacg
     2221 aaagcaaaag atttagttat gtatcacttg gatttcttcg gtaaatctaa tagttctgca
     2281 ttagataatg ttattcaatt aggtaaatct ggatttaaca atttactagc aaaaaataat
     2341 gtaattactt acaatgtatt attatctaaa aattatggaa ctgaaagttt atttaaagca
     2401 ttagaaggat atagaaaagt attcttacca acaacttcta acaatgagtg gtttaaagct
     2461 caaactaaag catatattgt tgaagaaaaa tcttctattc cagaagtaag taaaaaacaa
     2521 tcagaacaag gaactaagta ttctatagga atttatgata gattaactag tccgtcatgg
     2581 aaatatcaaa gtatggtctt accactatta actttacctg aagaaaaaac agtatttatg
     2641 atagcgaata tttcaacaat aggatttggt gcttatgata gatatagaag taaagtccat
     2701 cctaaaggag ataacttaaa taaatttgta gaagacaatg taagagaagc tgcaaaaaga
     2761 tttagagatc attatgatta ttggtataaa atattagagc ctgagaatag agagaaactt
     2821 tatagaagtt tattagtata cgatgcattt aaatttggtc gagataatac tgaagataaa
     2881 gtaacttatc aagctgattt tgaaactgat catccagcta taaaatactt ctttggacct
     2941 gcggggaata atgttgttca taatggacac ggagcatatg ctaccggaga tgcattctat
     3001 tatatggcat atcgtatgtt ggataaagat ggagctgtaa catatactca tgaaatgaca
     3061 cataactctg atagagaaat ttatcttgga ggatatggaa gaagaagcgg attagggcct
     3121 gagttttatg ctaagggctt attacaagca cctgaccacc catatgatcc aacaataaca
     3181 attaactctg tgttgaaata tgatgattca gaaaattcaa caagacttca agtagctgat
     3241 ccaactcaac gatttaatag tgcagaagac ctacataatt atatgcataa tatgtttgat
     3301 ttaatatata ctcttgaaat attagaaggt cgtgctgtag ctaaattaga ttataatgcg
     3361 aaaaatgatt tattaagaaa aattgagaat aaatataagc aagatccaga tggtaattct
     3421 gtttatgcga caaatgttgt tcgcagatta acgatggatg aagttaataa attaaattct
     3481 tttgatagtt taattgaaaa tgatattatt actagcagag ggtacaaaga ccaagaatat
     3541 aagagaaatg gttattatac aattgattta ttttcaccga tttattcagc tcttagtgga
     3601 gagaaaggga ctcctggtga tttaatggga cgtcgtatag cattcgaatt attagctgca
     3661 aaaggatata aagagggcat ggtaccttat atctcaaatc aatatgaaaa agatgcaaaa
     3721 gctgcgggaa gtaagattaa atcttatggt aaagaagtag gtttagttac agataaatta
     3781 gtacttgaaa aggtatttaa taatcgttac tcatcttggg tagaatttaa aaaagcaatg
     3841 tataatgagc gaatagctaa atttaataat ctaataagtg ttagctttaa taatccaaat
     3901 gtaagttggg gaagaactaa tagaataaca ataactagca tagccaacct tcaaaatatg
     3961 ataaatacgg ctgtcaatga agatgctgaa gattttagag cacaattata ccctgataca
     4021 aatagtagag ttcttaaact gaaaaaagca atatataaag cctatcttga ccaaacaaat
     4081 gattttagaa gatcaatttt tgagaataaa aaatagtgtt tactattagg aaataaaaag
     4141 tgaatgtgga ggattagaat tgtcattatt aaaaaaagat aaattttcca ttaggaaaat
     4201 aaagggtatt gttggttcga tattcttggg gagtttttta tttgcactgt cagttgttgg
     4261 tgtatcgact tatcattact tagattatag tactttgaca caaactgaac gtgatcaact
     4321 caaacaaggt agacctgatg aatcaaaaga gtcatatgct ttggtttatg aaaaagacgc
     4381 attaccaaac acaggaagtt ctcaatctat tatgactgta ttgggtttgt tagctatcgg
     4441 gagtcttatt gtgattatca caaaagataa aaagaggaaa aaaatagcta catttttgat
     4501 tgtaggggcg acaggtttag ttacactatc aactgcttca gcacttaatt tgaatgctaa
     4561 catccatgag tctggacgtg atggtgtgtt gcaaatttct ggttacagat atgttggtta
     4621 cttggagctt gatgatagaa ctgtttcgtc ggtttctcca gcatcaactg tttctccagt
     4681 tgagcaaccc aaagttgtga ctgacaaagg cgaaccagaa gttcagccag cgttaccaga
     4741 agctgttgta actggaaaag ggaaaactga agtacaaccg acattaccag aagctgttgt
     4801 gactgaaaaa ggggaaccgg aagtacaacc agtgttacca gaagctgttg tggctgaaaa
     4861 aggggaaccg gaagtacaac cagtgttacc agaagctgtt gtgactgaaa aaggggaacc
     4921 agaagtacaa ccagccttac ccgaagcagt tgtaactgaa aaaggcgaac cagaagttca
     4981 tgagaagcct gactatacgc aaccaatagg tgcaaacctt gttgagtctg aagttcatga
     5041 gaaactagca tacactgaac ctgtaggtac aacaggagta gatgaaaatg gaaacttgat
     5101 tgagccacct gttaacgata ttccagagta tactgaacca atatctacag tttcagaagt
     5161 tgcatcagaa agagaagagt tgccttcttt acataccgat attcgtacag agactattcc
     5221 taaaaccact atagaagaat ctgatcctag caaatttata ggcgataatt ctgttaaaca
     5281 agttggtgag gatggcgaac gtcaaattgt tactagctat gaagagttac atggcaaaaa
     5341 aatcagcgag tcagttgaaa cagtaacaat tttgaaagaa atgaagcctg aaattattgt
     5401 aaaaggtaca aaagaaagac caaaagaaaa aacggctcct gttttaacct tgaccaaagt
     5461 aacagaagat gctatgaatc gttctgccaa cttaaattat gagcttgata ataaagataa
     5521 tgctgaaata tcaagtattg tagctgaaat taaagatggt gatacagtag ttaaaagggt
     5581 tgatttatct aaagaaaaat taactgacgc tgtacaaaat ttggatttgt ttaaagatta
     5641 taagattgca acaacaatga tttatgatcg tggtcaaggt tctgaaacgt ctaaactgga
     5701 tgaaagacct ctgcgtttgg agttgaaaaa ggtcgaaatt aaaaatatcg catctactaa
     5761 tttagtgaag gtaaatgatg atggtactga aacacctagt gattttatga atgaaaaacc
     5821 ttcagaagaa gatgttaaaa aatgtactta aaaatcacta gtcgcgataa taaggtaact
     5881 cgtttaactg tagactctat tgaagaagtg actgaagaag gtcaaaaact ttacaaaata
     5941 actgctgaag cacaagattt gattcaacac acagacccaa cgaaggttcg taataagtat
     6001 gtttattata tagaaaaacc ccatcctaaa gaagataatg tctactataa ctttaaagat
     6061 ttagtagatg ctatgaatac tgataaaaat ggtacattta aacttggtgc agatttgaat
     6121 gccactggtg ttccaacacc taagaaatgg tatgttgacg gcgactttag aggtacattg
     6181 aagagtgtag aggggaaaca ttatactatc cacaacacgg agcgtccgtt attccagaat
     6241 attattggtg gtacagtaac caaagtaaat ctgggaaatg taaatatcaa tatgccatgg
     6301 gcagaccgca tcgcaccgat tgctgacact attaaaggtg gcgctaaaat tgaagatgtc
     6361 aaagtgactg gtaacgtatt aggtagaaac tgggtatctg gatttattga taagattgac
     6421 aaccaaggta cactcagaaa tgtagccttt atcggaaatg tgacatctgt aggtgatggt
     6481 ggtcaattct tgaccggtat cgttggtgag aactggaaag gactagtcga acgtgcgtat
     6541 gttgacgcaa atcttattgg caagaaagcc aaggctgctg gtattgctta ttggacacaa
     6601 aacagtggtg acaatcataa agttggtgtc gaaggtgcag tcaagaaagg aattgtgaag
     6661 ggtaccattc aggtagaaag tcctgttgaa gtcggcggtg ctgttggacg tttgagtcat
     6721 catggttata tcggggaagt cgtatctatg atgaaagtta agaagggtga aattttttat
     6781 ggttctagtg atatgaatga tgacccatat tgggtggcga ataatgtacg aggaaattat
     6841 gtagttaatg gtgtgagtga aggtacgata tcttatgctc gtgctaaaga acaccatcgt
     6901 atcaaaccaa tttcacagtc agaagcagat actaaaatta tgatgttagg tattacagca
     6961 caagattttg ctgtcaacga acctgtggtc aatcgcttaa accgtttaac cagaaaagaa
     7021 gatgaatata agtcaaccca agactataaa gtagatcgag atctggctta tcgtaatatt
     7081 gagaaacttc aaccatttta taacaaagaa tggattgtca accaaggtaa caaacttgca
     7141 gaagattcaa acttagctaa gaaagaagtc ctttctgtta cgggtatgaa ggatggacag
     7201 tttgtaactg acttatcaga tattgataag attatggttc actatgctga tggtactaaa
     7261 gaagaaatgg acgtcactaa gaatgctgat tctaaagtga aacaagttcg tgaatatacc
     7321 atcgctggac aaaacgttgt ttatacacca aatatggttg agaaagaccg taaccaattg
     7381 attcaagata tcaaagataa gttggcgtca gttcaattga tttctcctga agtacgtgct
     7441 ttgatggatg cacgtaagaa accagaagaa aatactgatg aacgtaagaa tggttatatt
     7501 aaagaccttt acttagaaga aagctttgct gaaacgaaag ctaatcttga taaattggtt
     7561 aaatccttag ttgaaaatgc agatcatcaa ttaaatagtg acgaagcggc tatgaaagca
     7621 cttgttaaga aggtggatga aaataaagct aaaatcatga tggctctgac ttatctcaat
     7681 cgttactatg atatcaagta tggggatatg actatcaaga acttgatgat gtttaaacct
     7741 gatttctatg gtaaatcagt tgaccttctt gatttcttga ttcgaattgg atcaagtgag
     7801 agaaatatca aaggtgacag aactttggat gcttatcgtg atatgattgg tggaactatt
     7861 ggtaagtctg aattacatgg attcttagat tacaatatgc gtctcttcac taacgatact
     7921 gatttaaatg attggttcat ccatgcagct aagaatgtat atgtatcaga acctcaaaca
     7981 acgaacccag attttgttaa taaacgacat cgtgcatttg atggtttgaa caacggtgtt
     8041 cataatcgta tgattctacc tctattaact cttaagaatg cacatatgtt cttgatttca
     8101 acttacaata caatggctta tagttctttt gagaaatatg gtaagtatac agaagaagct
     8161 agaaatgaat tcaaaaaaga aattgataag gttgcacatg ctcaacaaac atacttagac
     8221 ttctggtcac gtttagcatt gccaagcgta cgtgaccaat tactcaagag tgagaatagg
     8281 gtaccaactc ctgtgtggga taaccaaaac tatagtggta ttaaaggaat aaaccgtatg
     8341 ggttatgatg agaagaaagt accaattgcg ccaattcgtg agttatatgg tccaacttgg
     8401 aaattccata ataccaactg gaatatggga gctatggcat ctattttccc aaatcctaat
     8461 aacaatgacc aagtttattt catgggaaca aatatgatta gtccgtttgg tatttcagcc
     8521 tttactcatg aaactacaca cgttaatgat agaatgcttt acttcggtgg tcatagacac
     8581 cgtcaaggta cagacgtcga agcctatgct caaggtatgc tacaaactcc gtcaagtatt
     8641 ggtcaccaag gtgaatatgg tgctttaggt ttgaacatgg cttatcatcg tgaaaatgat
     8701 ggtgaccaat ggtataacta tgaccctgat aagcttcaaa ctcgtgaaga tatcgatcga
     8761 tatatgaaaa actataatga agcactgatg atgctagatc atgtagaagc agacgccgta
     8821 cttccacaat tgaatggtga taatagcaag tggttcaaga aaattgatag agaaatgcgc
     8881 agaaatcttg gggatggttt gaataactta gtagcaccgc accaatggga caacgttcgt
     8941 gacttaaatc aagaagagag ttctaagaaa ttatcaagta ttaacgattt gattgataat
     9001 aatttcatga ccaaacacgg aaatccaggt aacggacgtt atagaccaga ggattttaga
     9061 ccaaactcag cttacgtaaa tgtcaatatg atggcaggaa tttacggtgg gaatacgagt
     9121 caaggtgctc ctggttcatt atcgttcaaa cataatgcct tccgtatgtg gggttattat
     9181 ggatatgaca aaggtttcac tagttatgta tctagcaaat atcaaggtga agctgataaa
     9241 caaaaccagg gtagattagg tgatgatttc attatcaaaa aagtttcaaa caaccaattc
     9301 tcaaatcttg aagattggaa gaaatattgg tatcatgatg tgaaatccag agctgaaaaa
     9361 ggattcacag agattacaat tgatggacaa accattcaca actataatga actgaaagac
     9421 ttattcgaca aagctgtcac agaagacctc aagaaagctg gaaactactc aaatactgag
     9481 aatttgaaat ccaaagtctt caaagctctt cttaaaaaca cagacggttt ctttaatcca
     9541 ttgttcaaaa aagacattt
//
LOCUS       DBEJZV010000055         9530 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.55, whole genome shotgun sequence.
ACCESSION   DBEJZV010000055 DBEJZV010000000
VERSION     DBEJZV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9530
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.55"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            36..317
                     /locus_tag="ACL3S0_001973"
                     /pseudo
     CDS             36..317
                     /locus_tag="ACL3S0_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(451..1419)
                     /locus_tag="ACL3S0_001974"
     CDS             complement(451..1419)
                     /locus_tag="ACL3S0_001974"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR1312829.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1564..2379)
                     /locus_tag="ACL3S0_001975"
     CDS             complement(1564..2379)
                     /locus_tag="ACL3S0_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HGR1312830.1"
                     /translation="MKKSSILFIFILLLCIDLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2404..2901)
                     /locus_tag="ACL3S0_001976"
     CDS             complement(2404..2901)
                     /locus_tag="ACL3S0_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGR1312831.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2974..4335)
                     /gene="radA"
                     /locus_tag="ACL3S0_001977"
     CDS             complement(2974..4335)
                     /gene="radA"
                     /locus_tag="ACL3S0_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGR1312832.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSTNVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4349..4864)
                     /locus_tag="ACL3S0_001978"
     CDS             complement(4349..4864)
                     /locus_tag="ACL3S0_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR1312833.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4866..5309)
                     /locus_tag="ACL3S0_001979"
     CDS             complement(4866..5309)
                     /locus_tag="ACL3S0_001979"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGR1312834.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5366..5463)
                     /gene="ffs"
                     /locus_tag="ACL3S0_001980"
     ncRNA           complement(5366..5463)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL3S0_001980"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5496..5963)
                     /gene="tadA"
                     /locus_tag="ACL3S0_001981"
     CDS             complement(5496..5963)
                     /gene="tadA"
                     /locus_tag="ACL3S0_001981"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGR1312835.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(6164..7450)
                     /locus_tag="ACL3S0_001982"
     CDS             complement(6164..7450)
                     /locus_tag="ACL3S0_001982"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGR1312836.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7681..7917)
                     /gene="comW"
                     /locus_tag="ACL3S0_001983"
     CDS             complement(7681..7917)
                     /gene="comW"
                     /locus_tag="ACL3S0_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGR1312837.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            8183..9044
                     /locus_tag="ACL3S0_001984"
                     /pseudo
     CDS             8183..9044
                     /locus_tag="ACL3S0_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9079..9288)
                     /locus_tag="ACL3S0_001985"
                     /pseudo
     CDS             complement(9079..9288)
                     /locus_tag="ACL3S0_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9454..9527)
                     /locus_tag="ACL3S0_001986"
     tRNA            complement(9454..9527)
                     /locus_tag="ACL3S0_001986"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9491..9493),aa:Asn,seq:gtt)
BASE COUNT         3081 a         2255 c         1520 g         2674 t
ORIGIN      
        1 gaaaagcgac aaaacaactc attagaaaga atcatatgga acaattacat tttatcacaa
       61 aattactaga cattaaagac cctaatgtcc agattttaaa catcatcaat aaggatacac
      121 acaaggaaat catcgccaaa ctggactacg acgccccatc ttgccctgag tgcggaaacc
      181 aattgaagaa atatgacttt caaaaacctt ctaaaattcc ttatcttgaa acgactggta
      241 tacctactag aattctcctt agaaagcgtc gattcaagtg ctatcactgt tcaaaaatga
      301 tggtcgctga aacttctgat gacgtacagt catatttctt ttctttttat tatatcacag
      361 ttttaaatct agctttacta gattcaccgc tactatctat ttattcggaa aaaagacgaa
      421 aaaacctgag aatcatctca ggcttggtca ttaaattttt ttctcaatat cgaaaagtgg
      481 agaaagtggt cgtttttcat gaatacgtac gatagcatcc cctaggagat gagcgattga
      541 aatctgctca atcttatcaa tcaaacgctc ttctggcaga tagatggtat ccaaaacaac
      601 caatttctta atagctgatt tttggatatt gtccgtagca ggaccagaaa gaactgggtg
      661 cgtacagctt gcatagactt caacagcacc agcttccgca agagcatctg ccgcatgaca
      721 aatcgttcca gcggtatcaa tcatatcatc aatcaagata caagtcttgc cttcaacctt
      781 accgatgatg ttcataactt cactagtatt catcttatca acgctgcgac gtttatcaat
      841 aatagcgata gatgttttca aaaattctgc caacttacga gcacgagtca cccctccatg
      901 gtccgggctg acaaccacat agtcagaacc aaccatacca cgacgctcaa aataatctgc
      961 aatcagagga gcacccatca aatgatccac aggaatatca aagaatcctt gaatttgcgc
     1021 agcatgcaag tcgatggtca ataaacgatc cactccagct acttcaagca tatttgcgac
     1081 aagttttgaa gtgattggct cacgcgctct cgcctttcta tcctgacgtg catacccata
     1141 gtaaggcatg acaacattga cagattctgc actcgcacgc ttcaaagcat ctaccataat
     1201 caaaatttca agcagattgt catttacagg cgaactagtt gattgtagga taaagacgtg
     1261 tttcccacgg attgattctt caatgttgac ctgaatctct ccatctgaaa attggcgaac
     1321 acttgatttc cccaactcta tcccaatctc ctgcgctaca cgttctgcca attctttatt
     1381 agaagaaagg gcaaacagct ttaaatcaga aaaagacatg atttcctccg gtatatatgt
     1441 ataacttgtg cttttcacaa gattttccat ctaccattgt agcgcttttt gcactatttt
     1501 tcaatcaaaa ataaaagaag ggcaccatat ttgtaccctt gcatcattct tttgaaaaat
     1561 attctaggtc atcaactcat tgtgtttctc aacaaagcaa taagcatgat aaaaaccata
     1621 gagagcaata gccgtaacca ctggaatcgc taaaggcaac tctgtttcca actccacaaa
     1681 aggagagtta aacaagaagt gagttcccaa ggctaaacct agaaaaataa ggccctgttt
     1741 cttgccaacc ttctgtcctt tataggctct gtaaagcaag taaacaccta ctacagctag
     1801 acctgaaaaa gtccagtgag aggcaattcc tgagatgata cgctctaaaa ttcgcgaaat
     1861 agtaaagtca aagccctctg gcaaatccgt acgaatataa ccaatatcct caatcatttg
     1921 gaatcccaaa ccggaagcaa ttccaagtaa aaacaaagat tttaattttc gcacaggaat
     1981 caaagccaaa acaaaaacaa gtggcaataa tttcaagggt tcttctacca aaggagccac
     2041 aatagcactt tcaaaggcat ttaaaaatgg actatctggg aaaagaaccc ccagtaaatc
     2101 atgtatataa gtattagcaa aactagacaa ccagcctgaa aggaacatcc ctcccaataa
     2161 agacagaatc aaaaccttct ttggcaattc ccattttttc ccaatacgga agagaaaata
     2221 aagagccgga atcatgtaaa agagagctag aaagatagaa actcccatta gtccatattc
     2281 cgcacctgac ctcgaaccgt ccgtatagta gatggtttca tactgtaaat caatacatag
     2341 caataaaata aaaataaata aaatactgct tttcttcata cactttcttt ctaaatgaag
     2401 tatttataat tctacgactg tcatacttcc tgtatcaaca ttgtaaatag caccagagat
     2461 aatgacatcg tctggtatta ggggagactc gataagcagt tgcatatcct cgcgtacact
     2521 ctcttctata tcttggaagg gcaagaagtc ctggtctgac acatctacac ctaattcctc
     2581 ttttaaatac tcctgaaaag gttcattttc aaaggtctga gcaccacagt ctgtatggtg
     2641 caataccaca atctctcttg tccccatttg ttgctgggaa ataactagcg aacgaatcat
     2701 gtcttcagtc actcgaccac ctgcattccg caagatatga gcatccccaa gtgccaagcc
     2761 cagagcttgc gcaacgtgca gacgagagtc catacaggtc acaatagcta ctcttgtttt
     2821 gggtttaagt ggcagattta actgcccatg tagggcaaca taagcctgat tagcttgcat
     2881 aaactgttca aaatacgaca cgattccctc cttgaaaatt tgatagtcaa atatttctcc
     2941 tatcttatca tttttaagag aatttgtcac ggattatgca aagacctttt tcaaaacttc
     3001 ctgaatcgtt gtcacgccaa tgacctgaat ttccttaggc agagtgattc ctgtcaagga
     3061 attcttaggt acataaatct tagtaaagcc cagtttagca gcttcgttga tgcgttgctc
     3121 aatacgattc acgcgccgaa tctctcctgt caagcccagt tctccgacaa aacattcctg
     3181 aggattagtt ggcttgtctt tgtagctcga agcaatagca actgcaacag ccaagtcaat
     3241 cgcaggttca tccaatttaa caccaccagc agatttgaga taggcatcct gattttgcaa
     3301 gagaagccct gcccgttttt ccaaaacagc cataatcaag ctagcacggt taaaatcaag
     3361 tcctgtcgta gtacgcttgg catttccaaa catggtcggt gttaccaaag cctgaacctc
     3421 cgccaaaatc ggacgcgtcc cttccatggt tacaacgatg gaggaaccag tcgccccatc
     3481 caaacgctct tctaggaaaa cttgactcgg attgagtacc tcaaccaagc cgcccgactg
     3541 catctcaaaa atcccaatct cattagtgga accaaaacga tttttgaccg ctctcaaaat
     3601 acgaaaggtg tggtgacgct ccccttcaaa gtaaagcacc gtatccacca tatgctccaa
     3661 catacgaggc ccagccaagg ttccttcttt ggtcacatga cctacgataa agatggcaat
     3721 gttattggtc ttggccaact gcatgagttc agcggtcact tcacgcacct gagaaacaga
     3781 cccctgcacc cctgaaatct caggagacat gatggtctgg atggaatcaa taatgagaaa
     3841 gtctggctgg atacgctcca cttctgcacg aacactctgc atattggtct ctgcatagag
     3901 ataaaactca ctatcaatat cacctaagcg ctctgcacgt agtttaatct gctgggcaga
     3961 ctcctcccca ctgacataga gaactgtccc cacttgggac aactgggttg agacttgtag
     4021 gagaagagtt gatttcccaa tcccaggatc cccaccgata aggacgagac ttcctggtac
     4081 cactccgcct ccaagcacac ggttgaattc ctccatctcc gtcttggttc gattgacatt
     4141 ggtggaagtc acctcagcta gtttcatggg cttggttttc tcacctgtca aggacacacg
     4201 cgcattctta acttcggcaa cctcaacctc ttccacaaaa gaagaccaag acccacagtt
     4261 ggggcaacgt cccagatatt taggggaatt atacccacaa ttttgacata caaatgtcgc
     4321 ttttttcttt gcgatgacaa acctctttct atatctctaa ctcacactca atcacttggc
     4381 aaaaatcaat cttctcattt ggcacaaact ggcgcatgag cattcgatga gcaacaacta
     4441 ccacagtctg atgttctcga tacttagaca tacattctag aaaccgagac ttcatttccg
     4501 tagctgtctc atattgaata ggactattag gaagcaactc ccccttgttt tctaaaaaca
     4561 gtcttctagc tgtttcaaag ttttctattc ctgttttata gacctgccat tcatgtaata
     4621 aaggctctac tcttaaagga agacccgtag cacagaccac atacgaagcc gtttctaaag
     4681 ctcttgtgac tgcagaagat acgattattt cagctgacga gagtaaagga tttttgctca
     4741 atttctggac ttgctgccgt cccatctcag acaagggtgc caaatctatc ccaaatccta
     4801 tataagaacg ctcctctaac tcacggtaat ctggctcccc atgacgtaca aagataatct
     4861 tcattctagt gccctgtcga tccaaatcca ccagttcgaa cgccatcagc tgcatctcca
     4921 tctgcaatta agaaagtagc aaaaacagcc tggacaatac gctccccaac ttcaagaaca
     4981 acctcttggt ctgtgatatt cttcatctgc gcaaaaatat gcccttcatt tccaggattt
     5041 ccataataat ccccatcaat gaccccaact gagttaatta aaaccaagcc cttcttacga
     5101 ggatttgaag aacgatcata gaggtagaga acctcagtcg gctgcatata agccttaacc
     5161 cctgtcggaa ccaagacaat ctctcctggc gcaacaactg tacgcacagc aacctttaag
     5221 tcgtaaccag ccgcatgcgc tgtctcacgc ttgggcaata aattttcatc tgtaaaactc
     5281 gaaaccaatt caaaaccacg aattttcata attttctctt ttctattatc atttattcta
     5341 gattattcta tcttatttat tcggaaaaag cacgaaaaaa agagcacaca attcaaatcg
     5401 cttagggctg ctggattcct cccctgaccc gcttcacgca gaactgttgc tccactattt
     5461 attatatcac attcctattc attttaaaag caaaattatt ttttccgtct atttctaaaa
     5521 aaatcctgca tgatagctgc gcattcatct tccaaaattc ctatttcaac ctccacacga
     5581 tgattgagac gctcatctgt caagatatcg tacaaactcc cagcagcgcc aaatttctgg
     5641 tttttagccc catagaccac atttggaatg cgggcaagcc caatcgcccc actacacatg
     5701 acacaaggtt caatggtcac aaaaagtgtg caatccagca agcgccagct ctcctcactc
     5761 aagttcgcat cctctatagc cataatttcc gcatgcataa ccgctcgctg taattcctca
     5821 cgcgcattat gcccacgacc aatgatttcc ccatctttga caatcacaca accaattgga
     5881 atttcatcgt gttcaagagc aatctcagcc tctctcaaag cctccctcat aaagacttct
     5941 ttttcttcaa gcgtataata catctctttt ctcttttcct acttatcgat tttattatta
     6001 tatcatgaat cccaacacaa aaaaagccac cgaatgcggt gactctatag ggagattatt
     6061 atgaaaaaga aaagtttagg atatttgtta caacaagtta ggaggtcttc ttgtaaccgt
     6121 ctatagtata cccgacctat cttaaacaaa tcttaaaaat ctcttaggac caaacacttt
     6181 ctaaaatatt tgtttgttca cgaccaggac ctactgagaa agtagaaata cgaacgccaa
     6241 ccaattcact cacacgacga acatagttac gcgcattctc aggaagatct tccaaattgc
     6301 gaactccggt aatatcttct gaccaacctg gtaactcttc atagataggc ttgcaacgtt
     6361 tcaattgctc aagactagct ggatagtagt caatacgttg accgtcaaga tcataggcca
     6421 cacagatttt cacagtatcc aaaccgctca aaacatcaat agagttcaaa gaaaggttag
     6481 taataccaga aacacgacgg ctatgacgca tcacaactga gtcaaaccaa cctacacgac
     6541 gtggacgacc agttgttgta ccatactcat gacccacttc acggatacgt tctcccactt
     6601 catcaaacaa ctcagttggg aaaggaccat ctcctacacg actcgtataa gctttacata
     6661 cacctacaac cttgtcaatc ttgcttggac cgacaccaga accaattgtc acaccaccag
     6721 ctacagggtt tgatgacgta acaaatggat aagtaccttg gtcgatatct agcataacac
     6781 cttgtgcacc ttcaaaaagc acacgtttgc cattatcaag cgcatcattc aagataacag
     6841 atgtatctat cacgtatttc ttgatttgtt gaccatattc gtaatattct tcaaaaatat
     6901 catcgaaaac aatcgcttta ctgtcataca atttttcaaa aagacgattc ttttcagcaa
     6961 ggttacgttc taaacgctca cggaaaatat ctttatctaa aagatctgca atacgaattc
     7021 caacacgagc agccttgtcc atataagctg gaccaattcc cttaattgtc gtaccaatct
     7081 tattgtcgcc cttagcttct tcttgcaagc gatccaactc gatatgataa ggcaaaataa
     7141 catgcgcacg atcagaaata cgcaagttat cagttgttac accttcctca tgaagatagc
     7201 tcaactcttt tacaagagat ttaggattta caaccatacc attcccaatg acagatattt
     7261 tttcagggaa gaaaatccca gatggaatca agtgcaactt aaatttctta ccgtcaatca
     7321 caatcgtgtg accagcatta tcaccacctt ggtaacgtgc aatcacttct gcattcgctg
     7381 aaaggaagtc tgtaatcttc cctttacctt catcacccca ttgggtacct acaacaacaa
     7441 ctgaagtcat aattttgtct gagccctcag gctcttcctt tctcacatac atggcaggac
     7501 tctcacctgc aattatatct tacaatttat tataataaaa aatcgccttt ttatcaagaa
     7561 gaaacaatag aaagatttgc tatttccaac tattaaaaaa tgatttagaa aaattactag
     7621 ctatttacta ttatctttcc ataaaagagt aaattagttc ggaaatttac taaaattacc
     7681 tcaacaagaa ataaaacccc gattcattac caatttttca agatacaaac gataagcaac
     7741 acgataatgg taaacaataa aatccttacg acaaccaatg ccatatctca ctaaataata
     7801 aattaaaaat ttaaaatgaa catgttccca gtcaaaatta tcaccaaatg taggaccata
     7861 ctcttcttca atactatcat agaaattagc catctgctca taaatttttt gtaacataat
     7921 caaatactcc ttttcttttt tataaactta ttctaacaaa aaattttaca cattcactat
     7981 caattcctga attgttaaaa taccagcctc aacaagataa aaataggaaa agttgacaaa
     8041 atagaaacaa atttgctacc taaatttcaa acaattaaag ttctaaaaag accgccttaa
     8101 aacttttggg taaatcctat tagaactata atatttttat ataggtatta tggttctgat
     8161 tttctagtat aaaaaaattc aaactagaat tcttcttaga aaaggccgtt ttaagtgcta
     8221 tcattgctca aaaatggagc tcgctgagac ttctatcgtc aagaagaatc atcaaattcc
     8281 ttgtatcatc aaccaaaaga ttgctcagaa gctaattgaa aagacttcta tgaccgacat
     8341 tgatcatcag ttgtctattt caacttcaac tgtcattcgc aagatcaatg attttcactt
     8401 tgagcatgat ttttcgcgtc ttcctgagat tatgtcctag tacgttgaaa cagtccaggg
     8461 agtgactatt tcaatcggga gatggagatg agctttattg ctcaggactt tgataagctc
     8521 aatatcataa ctgttcttga gagcagaaca caagccatca tccgaaatcc catggataca
     8581 aggctatcaa gcgctactgg aaactcattc aacaggatag tcgtaaactg agtgataaac
     8641 atttttatcg tcctactttt cgtatgcact taaccaataa agagatttta aacaagcttt
     8701 tgagttattc ggaagacttg aaacaccact atcaactcta tcagctcttg ctttttcact
     8761 tccagaataa ggaaccagag aaatttttcg gacttattga ggacaatctt aagcaggttc
     8821 atcctatttt tcagactgtc tttaaaacct tcctcaaaga taaagaaaag attgtcaacg
     8881 cccttcaatt accttattcc aacgccaaac tggaagccac caataatctc atcaaactta
     8941 tcaagcacaa tgcctttggt tttaggaact ttgaaaactt caaaaaagaa aggacgaaat
     9001 ttgtcctttc taaatcttcg ctttcttcaa cccactacag ttgacaaaga accgaaaaat
     9061 gtctcgcctc taatatagtc aattgaaaca agaacaagac aaaagagcct cgtaaaaggt
     9121 attgcaactt ggtaatacct ttttgaggtg ctttttgata tgagcccatg ttttcttaat
     9181 aggattgtac tcaggtgagt agggaggaag aggtaaaagt tcatgcccaa actcctcgca
     9241 taaaagttct agcttaccca ttctatggaa tcttgcattg tccataatat agtagattga
     9301 aactagaata gtacacctct acttctaaaa cattgttaga attcgatttt actgtcctga
     9361 tcgatttgtc ctattcttat ttcattttac tataacacga aatagattat tattacataa
     9421 caaaaaagag gtctaaacct cttaactaaa ttactccgcc agtaggactc gaacctacga
     9481 catcatgatt aacagtcatg cgctactacc aactgagcta tggcggatta
//
LOCUS       DBEJZV010000056         9082 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.56, whole genome shotgun sequence.
ACCESSION   DBEJZV010000056 DBEJZV010000000
VERSION     DBEJZV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.56"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..134)
                     /locus_tag="ACL3S0_001987"
     CDS             complement(<1..134)
                     /locus_tag="ACL3S0_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HGR1312838.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     "
     gene            complement(146..580)
                     /locus_tag="ACL3S0_001988"
     CDS             complement(146..580)
                     /locus_tag="ACL3S0_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR1312839.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            851..1666
                     /locus_tag="ACL3S0_001989"
     CDS             851..1666
                     /locus_tag="ACL3S0_001989"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGR1312840.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            1685..2326
                     /locus_tag="ACL3S0_001990"
     CDS             1685..2326
                     /locus_tag="ACL3S0_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGR1312841.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFDRLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            2357..3358
                     /locus_tag="ACL3S0_001991"
     CDS             2357..3358
                     /locus_tag="ACL3S0_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGR1312842.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            3368..3997
                     /locus_tag="ACL3S0_001992"
     CDS             3368..3997
                     /locus_tag="ACL3S0_001992"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HGR1312843.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(4385..4761)
                     /gene="tnpA"
                     /locus_tag="ACL3S0_001993"
                     /pseudo
     CDS             complement(4385..4761)
                     /gene="tnpA"
                     /locus_tag="ACL3S0_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(5109..8312)
                     /locus_tag="ACL3S0_001994"
                     /pseudo
     CDS             complement(5109..8312)
                     /locus_tag="ACL3S0_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            8535..9011
                     /locus_tag="ACL3S0_001995"
     CDS             8535..9011
                     /locus_tag="ACL3S0_001995"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGR1312844.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFSKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
BASE COUNT         2605 a         1982 c         1641 g         2854 t
ORIGIN      
        1 aaatagtcaa ggttgagttc taactgccga ataaccttat cgattgcctg gccgacttct
       61 tctttcgtca gaagtggtac ttctaagaag cgctcaggcg attttatttt ttcaatcgta
      121 acctttttta tcattctttt accctttaaa tacccgattc gaaatcttct tcctcttcct
      181 ctgcatccgt tgaaaacaat tctttaccat ttacgactcc gccctgggcc gccactactg
      241 atttattaac aacctcatca aagctatgag ccattctagc aaagactgct tccattaaca
      301 tggctaagtt caaacccgaa agaacattca ttgttttggc tggattttct cccattatgg
      361 tagaagaaac cttgaatggc gatcctccca agagatcact taggattaaa acttcttctt
      421 catttgaaat tgcaagtaag attttttgct tgagttcatc tgctgacatt ccttccacaa
      481 agtcaattgc ctccacattt tcttgattgc ctgcaatcaa ttgtaaagaa ctataaatcc
      541 ctgtagcaaa atgtccatgc cctacaagta caattttcat cttttctcct ttcttgttta
      601 ggtttaccgg tttactttat attccccatt gtaatccttt atttttatct tgtcaatagt
      661 ttttttaaaa aaatattagc gctttcatta tatttttaat cattctaata gacagaaatt
      721 tcaaaatatt ccatttttaa ggaaaataaa tctttttata aataaaaata tttatttatt
      781 gacaaaaccg gtttactaga atataatttg gttatagaga agtcttaaca aatttgaaag
      841 gaagtatcaa atgacaaata catcattctc aattgagcag ttttctttaa aaggaaaaat
      901 tgctctcatc accggcgctt cttatggaat tggatttgct attgccaaat cctacgctga
      961 agccggcgct actattgtct ttaacgatat caatcaagat ctggtcaata aagggattga
     1021 agcttatcgt gaagttggca tcgaagccca tggatatgtc tgtgacgtga cagacgagga
     1081 cggtatccaa gccatggtca agcaaatcga acaagaggtt ggtgtcattg acatcctcgt
     1141 taataacgct ggtattatcc gccgagttcc aatgtgcgaa atgagcgccg ctgatttccg
     1201 taaggtcatc gatattgact taaacgcacc atttatcgtt tcaaaggcag ttattccttc
     1261 tatgataaag aaagggcatg gaaaaattat caatatttgt tcgatgatga gcgaactggg
     1321 acgtgaaaca gttagcgctt atgctgctgc taaagggggc ttgaaaatgt tgacccgcaa
     1381 cattgcgtct gaatacggtg gagccaatat ccaatgtaac ggaattggac cgggttatat
     1441 tgccactcct caaacagcac ctcttcgtga gttgcaagaa gatggttctc gccacccatt
     1501 tgaccagttc atcattgcaa aaacacctgc tgcacgttgg ggaaatcctg aagatttgat
     1561 gggccctgct gtctttctcg ctagtgatgc cagcaatttt gtcaacggcc acatcctata
     1621 tgtagatggc ggtatcttag cctacatcgg aaaacaacct gagtaaaaat agaaagaaga
     1681 tcttatgaaa atcgcattaa tcaatgaaaa tagtcaagct agcaagaatc acattattta
     1741 cgatagtcta aaagaagcga cagataaaaa agactaccaa ttatttaact atggtatgcg
     1801 tggagaagaa ggagaaagtc aattaactta tgtgcagaac ggactaatgg ctgccatcct
     1861 tttaaataca aaggcagttg actttgttgt taccggctgt ggtacgggtg taggggctat
     1921 gcttgcttta aacagcttcc ctggtgttgt ctgtggtcta gcagtggacc caactgacgc
     1981 ttacctttat tctcaaatca atggtggtaa cgccttgtct atcccttatg ccaaaggatt
     2041 tggctggggg gcagaactga ccctcaaatt gatgtttgat cgcttatttg ctgaagaaat
     2101 gggcggtggc tacccaagag aacgtgtaat ccctgaacaa cgcaacgctc gtatcttaaa
     2161 cgaggtgaaa caaatcaccc acaatgattt gatgaccatc cttaaaacaa tcgaccaaga
     2221 cttcctcaaa gacaccatct ctggcaaata tttccaagaa tacttctttg aaaactgcca
     2281 agatgatgaa gtcgctgctt atttgaaaga agtattagcc aagtaaagct attctaaacc
     2341 agaaaggaac taatggatga cgaaaatatt actgtttggc gaaccattaa ttcgaatctc
     2401 accattagat gccaccagta tcggcgatca tgttgccagt tcgacttatt ttggcggatc
     2461 agaaattaac atcgcttgta atttgcaagc cctgggtatc tcaacgaaag tctttaccgc
     2521 actccctgcc aacgagattg gagatcgttt tctcacattc ttgaaacagc accaaatcga
     2581 taccagttca atctgtcggc ttggcgatcg aatcggcctc tactatttgg agaacggctt
     2641 tggttgtcgt caaagtgaag ttttctacga tcgtaagcat acgagtatca gccagattcg
     2701 gccaaacatg ctagatatgg attctctctt tcaggggatt agccattttc attttagtgg
     2761 aatcaccgta gctatcggtc aagaggtccg tgcgatcctt ctcctactct tggaagaagc
     2821 caagcgccga ggaattgtcg tttcaatgga tctcaatctg agaacaaaga tgatttcagt
     2881 cctagaagcc aagtatgaat tttctaagtt tgcacgtttt actgactatt gcttcggtat
     2941 tgatcctctc atgattgatg accaaaatct agagatgttt ccaagagaca gtgctagcct
     3001 agaagaggtg gaaaatcgca tgcgactttt aaaagaagcc tatggtttca aggccatttt
     3061 ccataccctc cgctctagtg atgagcaaga caaaaatgtc tatcaagcct atgctctgga
     3121 agaacgattt gaagagtctg tccaactaaa aactgcagtc tatcaacgaa ttggtagcgg
     3181 ggatgccttt atatctggtg ccctttacca actactccat cattcctccc taaaaactac
     3241 cattgacttt gcagttgcga gcgcaactct caaatgcact cttccaggag accatctctc
     3301 cacttccgca actagtattg aaaatttact ggcaaatgca caagatatca ttcgttagga
     3361 gaattacatg accaaatcag atacgattat tgaactaaaa aaacagaaaa ttgtcgctgt
     3421 cattcgagga aatacaaagg aagaaggact acaagcctcg attgcttgta tcaagggcgg
     3481 tatcaaagct attgaaatcg cctataccaa tcagtatgca ggacaaatca tcaaggaact
     3541 tgtagacttg tatcaggacg atcagagtgt ttgtatcggt gcaggtactg tgcttgatgc
     3601 cgtaactgct agagatgcca ttctagctgg agcaaattac gttgtttctc catctttcca
     3661 tgctgaaact gcgaaaatgt gcaatctcta cagcacaccg tacattccag gctgtattac
     3721 cctcacagag atcacgactg cacttgaagc cggtagtgaa atcatcaaac tcttcccagg
     3781 tagtactctc agtccagcat atatctctgc agtcaaggca ccgatcccac aagtttccgt
     3841 aatggtaacc ggaggagtcg gcctaaacaa catccctcaa tggttcgctg ctggtgcaga
     3901 tgccgttgga attggtggcg aactcaataa actcgcttcc caaggcaact ttgaccgcat
     3961 cagcgagatt gcccaacagt atattacact cagataaaat cataactacc cgtctaacgg
     4021 gtggtttatc tcagagctat aagcccaaat catcagccag cgcctaaaga cgctggcttt
     4081 cacgttgttc aagccttatt gctcttgact cgtcacttgc ctctttaaga gactttggta
     4141 ttacttacca ctatccctaa agggatcctc atattctttt acactcaatt tatctagtgt
     4201 tatagtagat tgaaactgga atagtacacc tctgcttcta aaacattgtt agaaatcgat
     4261 ttgactgtcc tgatagattt tgtcctgttc ttatttcatt ttactatata tcatgcttta
     4321 ctcgttctca aattttcata ctcgtgaaga aatcatccac tcgataattt ctttaatctt
     4381 gactatattt cttaattgtg gcttcattaa gccctactgg acttacataa taaccttccg
     4441 cccagaaatg ccgattccca aacttgtact tgagattggc gtgtttgtca aacatcatga
     4501 gtgcactttt gccttttaaa taccccataa aacttgaaac acttagcctc gacggaatac
     4561 tgactaacat gtgtacatgg tctggcatta agtgaccctc gatcatttca acacctttat
     4621 aactacacaa gcgatgaaat atttcgccta aactacttct atattgatta tagatgactt
     4681 ttcgtctata cttaggggtg aacacaatgt gatagaacac ctccactttg tgtgagataa
     4741 actatgagcc ttttgtgcca tattttttct cctttcgctt tacaattgga ttgaacacct
     4801 ttattgtatc gcgtttggag tttttttggt ataaccttcg acgcgcacct cacggagcga
     4861 gacggactaa tatagtggag tgaaatagga tacgaacaaa ttgattagga aaatcaaatg
     4921 aatttataga aatcttttag cagttatgac gtcctattct agtttcaaaa cgctatagtc
     4981 acataatgaa gtaaaaaaga taagtatcaa cttatctttt ttaaaagaaa aatccgaaga
     5041 tatttggcct tcttcggatt ttttctattt tccacagttt catgtaattc atctagatga
     5101 tgaacaaatt agttgttctt tcctctacgg aataaataaa acgccccaag tagcaagaac
     5161 cctagacttg ccaagattga ctgaccttct cctgtctgag ggagattctt ttgatccgaa
     5221 tggttctttt cctcttcaga tttttccttt tcttttgaat tctgtacttg tggctgagct
     5281 gcttgctcta gctttttaaa gacttcctga tctggagctg attcctgggt ttcaggatta
     5341 tagtaggcaa tcttatattc atccccttct tttcgaatgg tatagactcc acgtttcaaa
     5401 acttggaatt ggttggaaat agtagagaca gaatcatcat atttcacaat gccccaaact
     5461 ccttgtttgg catcataaac agactgaagg gtttcgttat tttcgatgag gctactttct
     5521 aactctttta tcatttgatt gaaggtggca cgacccacgt tagggatgag catatagcca
     5581 taagaatctc cattttgctt atgagcctga ctaatcgtaa gaaattcatt ttcaacttcc
     5641 ttgtctgact gtccttcatt gatatccttc caggctccct tttgcaaagc cttactcata
     5701 ctgattgaac tcttcttaaa gaaaaagtaa ccaatattct ttttcgaatc ggacgattct
     5761 aaaaagacac tttgggtttc aggataatcc ttttcttgtt ctgtaaggga ggcttcttta
     5821 tcattgacat agactttata tggattactt gattccagtt ttctctggtc aattgtagtt
     5881 gcagcagtat ctgttgaagt gttttggata ttgcttccta aaaaggcgat cttatccttc
     5941 agcataaacc agctcttatg agcagtcaat gtttgattcc agttggtgaa atccatggtt
     6001 gctgtcgcat tggcatcatc tagtttgctc gttccaacga aagcagacgg tagaacttta
     6061 cctgtatcgc tatccgctct cttagcatcc gtctctgttg taccaggcat cttatatgga
     6121 ttaactgttg gccagtagcc atcgctatag tgactcaaat cgccattgta aagatagaac
     6181 atcccatcac tcgtatacca accatgttta ttttccttgt tcatgtgttc gtaattcaag
     6241 gtacgactgg aaaagagtga caagccaaat ccaaaccctt tctctgcatt gtacatggct
     6301 gttttatcca tcttgttaaa ggcagatagg taacttgttc ttggaacact tgcgactcct
     6361 gcatcactta acaaggattg catcaaactg atatccttat aagtcttcaa attcttaaag
     6421 acatcataat aactatccga ttgaacaatg gtcttcacaa gactctgcaa acgttgtttg
     6481 gtttctcctt cagacatatc cgctattcgg tgaatccctc ttagtacttc tactgcggcc
     6541 acgtgcccct cgctatttgc acgactgatc gagcgtccac gactcatatc catcagctct
     6601 ccattcacca gcaaaggagc aaacgattta tcaatccagt ggtacatggt ttgcatttta
     6661 tctttatcga ttggattctt ggtcttttga atgactggca acagttgaga caggccatca
     6721 atcaaaacat tcccataagc acccgtatag gcaacattgg tatggtcgat ataggatcca
     6781 tcttgataaa aaccttcacc ttggtctacc aacttgaaca cttgctcaat cgagcgaatg
     6841 gtagaagaaa tttcttgatc atccttacgc agtaaaccag ctattacttt tactcttccc
     6901 atatcaacta agtttccacc tagagcctta aatgggttat cagtcgtctt tcggaaatgt
     6961 tcgggatctg gtacaaattt ttcaatcaca tctgtatatt ttttaatttc ctcatcagag
     7021 aagtattctt tcatcagaga caaggtattg ttgatggcac gaggtgtacc gatttcataa
     7081 tcccaccagt tcccaacaat gctcttttca ctattgtaga catgtttatg catccattcc
     7141 atggaatccc tgactgttcg aacgacagtt tcatcttgat aataacgaga agaaggattg
     7201 gtcacttgct tggccatctc ctccaatttc cgataagtgg cagtcagatt tgcagacatt
     7261 ttataatttg aaaatttttc ccacaaatag gtgcggtccg cctaacttga aatactagat
     7321 aggctatcag ctacctttcc ttccaattcc tggtttaatt tggccatctg ttcattttta
     7381 gaatcatagt attgattccc agcgatgatg ccattccagt catccaaacg gtctgtgtat
     7441 gcatccttaa cagaggctag aatcttcaaa ggaatctttt tcacttcctt gccatcttta
     7501 ctgacaatga cattggttgt cccttcctta agaggttcta aaattccatt tttgactgaa
     7561 gcaacgtcag gattttctac cttataagta tagtccgcaa gagaaaaaac atattttttt
     7621 ccaattggta aatcaatctt ttcctcaagc tgtttatctg tttgagaatc ctcagaaagc
     7681 tggtctgcta cctctaccag ctcaatatcc ttaaaggaaa cagtcccagt tcctgtttca
     7741 tagaataact ccagcttgat tttatcaaca tctaaagtcg ggctatagtc tgcttcaatg
     7801 gtctgccagt cctttgttcc tgacgtcgtt gcagaattcc acaatcgctt gtccttacca
     7861 ctttcctcaa tgatacgaac tttggcaatc ccgactttat tatctgtttt aatcttgaaa
     7921 cgcagtttat actttttctt agcttcaata ggaaccatac ggtgaaccac tgcccttaat
     7981 ttctcatggc ttgagatagt gatagcccca tccttagcct caatgactcg agttgaggca
     8041 tctgcagaac tattcttctg gtctacccaa gctgaccacc cctgagcttt gctccctgtc
     8101 cacggactgc ttccgtcctc cgtctgacta aaatcaccat tttcaactaa attttttgta
     8161 tccctttgct gatactgaac ttccttctgg ctttgctgaa tggtattcgt agtcgtttct
     8221 tccgctccaa ctgtcatata atggtttaat aaaaatcctg ataaaacaag tgaagacaaa
     8281 ctcacaatga gcttctttgt ttttgtttgc atgtatacac tccaataaac atattgtaaa
     8341 atcaatagga actaaatctc aaattagaga tttatagcaa ctaagtaaac cggtttaatt
     8401 aaatcatacc atttttaaag ttatttgtaa acggtttcta tcatattgag ggcttattct
     8461 tcaacaatat cttccatccg actcgacgaa aaaagtaaaa actgttacaa tgtagaaaaa
     8521 gaaaagaggc cctcatgact tcactttatg atttttccgt tttgaaccaa aataaccaag
     8581 caactccctt ggatagctat cgtggcaaag ttctcttgat tgtcaacact gctactggat
     8641 gtggtttaac gccccagtac cagggacttc aagaactcta tgaacgctat caagatcagg
     8701 gcttcgaaat attggatttc ccttgcaatc agtttatggg acaagcaccc ggcagcgcag
     8761 aggaaatcaa cgccttctgt agcctacatt ttcaaaccac cttcccacgt tttgccaaga
     8821 ttaaggtcaa cggtaaggaa gcagaccctc tctatgtctg gttaaaagac cagaaatctg
     8881 gcccactagg aaaacgaatc gaatggaatt tctctaagtt tctcatcggt cgagatgggc
     8941 aagtctttga acgcttttct tcaaaaacag acccaaaaca aattgaagag gcgatacaaa
     9001 ctctactata attcacaatc tcactatgat taggtttcct ttaacctgat gaatagtgag
     9061 attttttgat gggctttgac tt
//
LOCUS       DBEJZV010000057         8098 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.57, whole genome shotgun sequence.
ACCESSION   DBEJZV010000057 DBEJZV010000000
VERSION     DBEJZV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8098
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.57"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(10..714)
                     /locus_tag="ACL3S0_001996"
     CDS             complement(10..714)
                     /locus_tag="ACL3S0_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR1312845.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(784..2610)
                     /gene="glpO"
                     /locus_tag="ACL3S0_001997"
     CDS             complement(784..2610)
                     /gene="glpO"
                     /locus_tag="ACL3S0_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGR1312846.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(2652..4160)
                     /gene="glpK"
                     /locus_tag="ACL3S0_001998"
     CDS             complement(2652..4160)
                     /gene="glpK"
                     /locus_tag="ACL3S0_001998"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGR1312847.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMIKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(4319..5746)
                     /locus_tag="ACL3S0_001999"
     CDS             complement(4319..5746)
                     /locus_tag="ACL3S0_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1312848.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            5911..6783
                     /gene="hslO"
                     /locus_tag="ACL3S0_002000"
     CDS             5911..6783
                     /gene="hslO"
                     /locus_tag="ACL3S0_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGR1312849.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            6770..7750
                     /gene="dusB"
                     /locus_tag="ACL3S0_002001"
     CDS             6770..7750
                     /gene="dusB"
                     /locus_tag="ACL3S0_002001"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGR1312850.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(7980..>8098)
                     /locus_tag="ACL3S0_002002"
     CDS             complement(7980..>8098)
                     /locus_tag="ACL3S0_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312851.1"
                     /translation="SQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
BASE COUNT         2306 a         1927 c         1615 g         2250 t
ORIGIN      
        1 gagtataaac tagaaaagtg agaatacaag cactgccaag gctgctccga taacagggcc
       61 tacaacagga atccaagcgt aagaccagtc tccgtctccc ttgtttggaa ttggcaagat
      121 gctgtgcatg atacgaggtc caaggtcacg agctgggttc aaggcataac ctgttgtccc
      181 acctagtgat agaccgatac cgacaatcaa agttcccact gcaaaggttc cgatacctgc
      241 ctgaaaatcg taaagaccca aagcaaagat tgtcaacacc aaaacaaagg ttccaaggat
      301 ttcgctaatc aagtttgata cagtatcctt gatggctggt ccagtactga aggttgccag
      361 gatattgcct gcattttctt ctgcctcata gtgaggtttg aattgcaacc aaaccaaaat
      421 ctgacccagc atggcccctg cgaactgggc taagatataa ggcaaaacgg aagcccaagg
      481 caaaccacct tttaaggcca caccgatggt cacagctggg tttaaatgag ctggactgag
      541 cttgccagat acaaagactg caaccgcaac tgcaatcccc caacccatag taatcacaat
      601 ccaacctgag ctattgctct tggttttagg aagaaccaca cctgcaacaa caccatttcc
      661 tagaagaatc aggattaaag tccctagaaa ttctccaaat aattcattca tcatctttct
      721 gtctccatta aaaagaaggg gcgggcgaca aggaatgctg ccctccacct cttttatttt
      781 ttcttaattt tttaattctg ctaaatcgtt gttagcgaga gctgcttcga catcagcacg
      841 gtaagttgct ttttcttctt ctgtccagtc atagaatcgt cccatttcat ccaaaactgg
      901 ctcaacgatg ctatccaagc tatcacgcat aaagagcata tggttggtac gacgaagaag
      961 gaagtcaact gggctaagag ccaactcgtt gcgcattgca tagtgaaggg acaaagtatc
     1021 tgccaagctg agtcctggcg cttgttccaa gctgtgagca agtgcaaaga ctttcggtgc
     1081 atttgaaccg taaagatttg ccagatagtg agcttccttg ctatccaaac cacgtgatac
     1141 tccaagttgc gcaaaggctt cgatttctga atccacattt gctgggttca attctccacc
     1201 tgaaacaggg taagttttag aattgatcaa tttaaagcta cggtcaaatt ctgctttgag
     1261 gatgtcaacc acgcgctcca tagctccttc agccatctta cggtagtctg tgattttacc
     1321 gccagcaaga gtcaaaagac cattgtcatc acggtccaag ctagacccac gagaaactgc
     1381 agatggatcc aaatatttct cagatgtgct actttcaagc ttgctgacag cagactcaac
     1441 atcttcacgt gttttttctt tggagagata agattcaaca gtcgcaatca agttgtcaaa
     1501 gctttcatca ctgatggtac cgttatttcc accattatag tcagaggcac tgttccctgc
     1561 aatcaatgga cgaagacctg cccagctgct ttcgatatca tcaatggtga tgttggattc
     1621 tggaaagcgg ttgttgacaa tgccaagtag ataatctaca tcttcttgag ttacttttgg
     1681 atgctccaaa tcacctgtgt agtctgtatc agttgtacca aagtaagtct tgttttcacg
     1741 tgggagaaca aagaccatac gaccgtcacc caaacctgtg tcgaagtaaa ctggctgtga
     1801 aaccttgatt ttgcttgaat ccactaccaa gtgaactccc ttagttgggc gcatttgtga
     1861 gaattgcgtt cccttattag acaaattacg tactttatca ctccaaggac ctgttgtatt
     1921 aataaccaga cgggccttga tttcaaatac ttggtctgtc aagagatcac gagctacaac
     1981 acctgtaatc ttgccacttt cgtcaaagag gaagccttct gccttcacgt ggttggcaat
     2041 gagggcaccg tcttggttgg cacgtttgat gttttcaatc acgagacgcg catcgttgtt
     2101 acggaagtca agatacactc cacctcctac caagccttcc ttcttcaagt ttggctggcg
     2161 ttccaagact tctttcttgc tcaaaacctt gttcgcagtt ggtgtgttgc taacacctgc
     2221 caagaggtcg tacaagtcca tggctacttt aagacggaag aggctaaagg ttgctccatc
     2281 ttcatcgtaa actggtaaga gcattggatc tggttttgga atgtgtggag cgatttgttg
     2341 aaccactgca cgttcagaaa ccgtatctga gaccacttct acgtcaaatt gtttgaggta
     2401 acgaagtcct ccgtgaacca attttgttga acgactagat gttccttctg caaagtcttg
     2461 catttcaatc aaaccagtct caagaccgct agctgccgcc tgcaaggcta caccagctcc
     2521 tgtgattcct ccaccgataa tcaagaggtc cagggtgcgt tcctgcattt ttttaattga
     2581 caattcacgt gttttctttg aaaattccat atttacacac tttctaaata aatcgcttta
     2641 ttctgccagt attagtcgtc tacttccgca aagacttgag ttgctttcac agccttcttc
     2701 cagcccttgt agagttgttc cttgcgagat tcgttcatag atggctcaaa gagttctcct
     2761 gtctcgttca agagtttcaa ctcgtccaag tctttccagt accctactga caaacctgct
     2821 aggaaggccg ctcctagagc tgttgtttcc aagtttttag cacgtgcaat atcaatgcct
     2881 aaaatatccg cctggaactg catgaggaag ttgttcatgg ctgcaccacc atccaccttc
     2941 aatacttgaa tggcggtctg agtatccact tgcatggtgt cgatgatgtc acgcacttga
     3001 taagcaatag attgcaaagt cgccttgata aagtcttctt tgcttgttcc acgagtcaaa
     3061 ccaaagacgg aaccacgagc attttggttc cagtatggag cgcctagacc tgtaaaggct
     3121 ggaacgacat aaacttcatc gttgttgtga gaatcacgag cgtatttttc agattctggt
     3181 gaattttcaa ccatgcgaag accgtcacga agccactgaa tagcacttcc tgcgatgaag
     3241 atagaacctt ccaaggcata ataaacctta ccgttgattc cgtaaccaat ggttgtcaag
     3301 aggttgtttt cagacaactg catctcttcc ccagtattca tgatgatgaa agagcctgtt
     3361 ccataagtat tcttaatcat acctggctca aaagccaact gtccaaagag ggctgcttgt
     3421 tggtccccag ccatacctga gattggcacc tctccaccgt agaaatggaa tggagctgtc
     3481 ttgccgtaga tttcggagtt agaacgaact tctggaagta tagccttcgg aatgttaagg
     3541 atttccaaaa tctcatcatc ccatttgagt tctttaatgt tataaagcat ggtacgagct
     3601 gcatttgagt agtcagtcac gtgagccgca ccgtcagtca atttccaaac caaccaagta
     3661 tcgatagtac caaagagcaa ttcccctttt tctgctcgct cttgagcacc ttctacatga
     3721 tccaaaatcc aacgaacctt ggtagcagag aagtaagcat caataatcaa accagtcttt
     3781 tcatggaatt tttccacata accttggctt tttagttgct cagccaaagg tgctgtctgg
     3841 cgtgactgcc aaacgatagc attgtagata ggaagtcctg ttttcttatc ccagacaacc
     3901 gttgtttcac gttggttggt aatcccgatt gcctcgattt gatttggctt gacaccactt
     3961 tcgatgaaag cacccgcaat aactgactga acagagttcc aaatttcatt ggcattgtgc
     4021 tcaacccaac ctgcctgagg gaaaatctgg gtaaactctt tttgactcga gctaaccttt
     4081 tccccttttt tgttgaaaat gatggcacga gaacttgtag ttccctggtc aatggccatg
     4141 atgtattttt cttgtgacat gtactgtcct cctgataaag atcttgaggt gtttcctctt
     4201 tacacttact agtatacaaa ataaagcgct ttcttgttta tcaacttttt ttaattttta
     4261 aaaaaatgtg aggagattgt gtgaatttca caaaaaagac ctggattaac caagcctttt
     4321 aagtgaataa taactgacga atccctgcca aatcttccat atccaagtca ttttttaaat
     4381 aatagactgg tgtctgttcc ttcttatgaa tagggttatt ggtaaccagc aaatcataat
     4441 gccgactagg gtcataggct tcaatggtaa taaaacgatt gtattccaaa taccgtttca
     4501 aaatggctgc catccttgaa aagacaagaa aaccagatgt caaatccaga ccaatccgca
     4561 tatgctggcc accgttttca gccatatatt cgattaactg gagccattcc cagagaatct
     4621 tcttatctaa atctgtcccc tgttgaaaag taggtagagc atgaaaaatc tcctctgctg
     4681 tctctttaaa atcatgttcc atcagtaaat atggatgacg attctctaac tggtacttgt
     4741 agcgatcctg taaaatatag cccttataga gatagacttg agcacaaagc tgactgagtt
     4801 cataggtgac atggtcctct gtataatccc ccaatagttc ctccttcttc atttcttgaa
     4861 tcaattgcgt cagtaaatct gccaactgcc ctccaaaacc aagaatatac tccatagtat
     4921 gaagaggaag aatgcgatga gataggagaa aagagaagaa tatcatcatc tcaccatcct
     4981 caactcctag tggaatatgt tgcccagcaa aaaaggacgg aacctttctc agcaaacgaa
     5041 gataaaagat attgtcaaaa taccctcgca ttttctcttc tatgacttga aactgacaag
     5101 cattgacccg aagacgttgt tgactgatgt gagcccagag aaccaagtcc aatttctgcc
     5161 ccacagacaa acttgcaccg cagatttcct ctaaattggc aatctcctgt tttctctctg
     5221 gtttctgcat gtgaccttcc cattcctgac tcgaccagac ctttcggaaa agacagaaat
     5281 agaaatagcg aatctgatgc tctggacctc gccaacgtcc attttggatg gataaatcaa
     5341 attctgacaa aatctgattt aaaccagcca agtgacgacc aagcgtagcc tcgctaatca
     5401 ccaattcttg agccagctga tgggctaaaa actgttggtg gtagagaaga taaaccaaaa
     5461 tctggtattt aacagcactc tccaaaaaca agctccgaat atctctcccc ttggtagctg
     5521 caccgataga cagacgcaga ttttcatctt ctgagtgaat agccagctct aagccactat
     5581 ccaaagcctt gtcattgagc agggtgacat atttggttag ggttgctttt gaaaatcctg
     5641 tttcttccat tacagccttg acggtcgtct gagactcttg taatagaaag gaaaggattg
     5701 aaaattgacc acactcggct ttctccatca aatctcctaa atacatttgt tacccctttc
     5761 attttctacc ttaagcatag cataaatctt acaaatgcta aaataatctg tttctctttt
     5821 tattttcatg ctgatttcct ggtccattat cctgaaaatc agtaaacaca cggctccccc
     5881 tttgggcatt tttatgctaa aatagtagct atggataaaa ttattaaaac tatatcagaa
     5941 agcggagcct ttcgtgcttt tgtccttgat agcactgaaa ccgtccgcac tgctcaagaa
     6001 aaacatcaaa cccaagctag ctcaactgta gcgcttggtc gaactcttat cgccagccag
     6061 attctcgcag ccaatgaaaa aggaaatacc aaacttacag ttaaggtgtt gggatctagc
     6121 tctctaggtg ctattatcac cgtcgctgat accaagggga acgtcaaagg ctacgttcaa
     6181 aatcctggtg ttgacatcaa aaagactgcg actggtgaag tcctagtcgg accttttgtt
     6241 ggaaatggtc aattcctcgt tatcacagac tacggtactg gaaatcctta caactctata
     6301 actcccctca tctctggaga aatcggtgaa gaccttgcct tttaccttac tgaaagccaa
     6361 caaacgcctt cagcggtcgg cctcaatgtc cttttggacg aggaagacaa ggtcaagatt
     6421 gcaggtggtt tcctagttca agtcttgcca ggagccaaga aagaagagat tgctcgcttt
     6481 gaaaaacgca tccaagaaat gccagctatc tctactcttc tcgaaagcga cgaccatatc
     6541 gaagccctcc tcaaggctat ctacggggac gaagcctaca agcgtctttc tgaagaagaa
     6601 atccgtttcc aatgtgactg tagccatgaa cgctttatga acgctcttgc cagccttcca
     6661 agctcagact tacaggaaat gaaagaggaa gaccacgggg tagaaatcac ttgtcaattc
     6721 tgccaaacta cttacaactt tgatgaaaag gacctggagg aactcattcg tgacaaatct
     6781 taatacacct tttatgattg gcaatgttga gattcccaat cgtaccgttt tagcgcctat
     6841 ggctggcgtg accaactcag cctttcgtac catcgcaaaa gagctcggag ctggactcgt
     6901 tgtaatggaa atggtctctg acaagggaat ccaatacaac aacgaaaaaa ccctgcacat
     6961 gcttcatatc gatgagggcg aaaaccctgt ctctatccaa ctttttggta gcgatgaaga
     7021 cagcctagca cgcgcagcag aatttatcca agaaaacact aagaccgata tcgtcgatat
     7081 caacatgggc tgccctgtca acaaaatcgt gaagaacgaa gctggagcta tgtggctcaa
     7141 ggatcctgac aagatctact ctatcatcaa caaggtccag tctgtccttg atatcccact
     7201 tactgtcaaa atgcgtaccg gctgggcgga cccatctctt gcagtagaaa atgccctcgc
     7261 tgctgaggct gcaggtgttt ctgccctcgc catgcatggc cgtacccgtg aacaaatgta
     7321 tactggccac gcagaccttg agacccttta caaggttgcc caagctctaa ccaagattcc
     7381 attcatcgcc aacggtgata tccgtactgt ccaagaagcc aagcaacgca tcgaagaagt
     7441 tggtgctgac gcagtcatga ttggccgagc tgccatggga aatccttacc tcttcaacca
     7501 aatcaaccat tactttgaaa caggagaaat cctacctgat ttgacctttg aagacaagat
     7561 gaagatcgcc tacgaacact tgaaacgatt gattaacctc aaaggagaaa acgtcgcagt
     7621 tcgtgaattc cgtggcctcg ctcctcacta cctccgtgga acatctggcg ctgccaaact
     7681 ccgtggagcc atttcgcaag ctagcaccct ggcagagatt gaagctctct tgcaattgga
     7741 gaaggcttaa tagtttaaaa cccgtaactc tcttaaagag tctcttgagt gccgccattc
     7801 tttcctcatc aaaaaaactc cgtagtctct agcgctataa atccggctag agattacaga
     7861 gttatttttt aatctaaact tcctacaagg gtatattatc tactgaaagg atatggtatt
     7921 tgtagggaat actttaaaaa gttcttacag gaagtcagta ttaactagtt atattaggtt
     7981 tagtttaccc attcaccatt ggcattgact ccatagccat ctacagttgt gttgactgca
     8041 agggcacctg agccattgac atagtaccat ttatctgata ctttgaacca ttggcttg
//
LOCUS       DBEJZV010000058         7946 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.58, whole genome shotgun sequence.
ACCESSION   DBEJZV010000058 DBEJZV010000000
VERSION     DBEJZV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.58"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            209..2191
                     /locus_tag="ACL3S0_002003"
     CDS             209..2191
                     /locus_tag="ACL3S0_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1312852.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2492..7795
                     /locus_tag="ACL3S0_002004"
     CDS             2492..7795
                     /locus_tag="ACL3S0_002004"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGR1312853.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTASTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRIIPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMEALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQSSMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKMPDYKQEIA
                     RPETPKQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
BASE COUNT         2618 a         1505 c         1733 g         2090 t
ORIGIN      
        1 ataatatcta tagtggattt acccactaca aatattatag aacctaaaaa ttccttgact
       61 atgtgatata gttgagggat ttttaaatga tattcatatt ttttgcaaag atgttgtttg
      121 aaaaataatt ttcaaaaatt ctgaaaattc tgttgacaac tttctgaaaa gagtctataa
      181 tggagagaaa gttttaaagg agaaaatgat gaaaagttca aaactacttg cccttgcggg
      241 cgtgacatta ttggcggcga ctactttagc tgcatgctct ggatcaggtt caagcgctaa
      301 aggtgagaag acattctcat acatttatga gacagaccct gataacctca actatttgac
      361 aactgctaag gctgcgacag caaatattac cagtaacgtg gttgatggtt tgctagaaaa
      421 tgatcgctac gggaactttg tgccgtctat ggctgaggat tggtctgtat ccaaggatgg
      481 attgacttac acttatacta tccgtaagga tgcaaaatgg tatacttctg aaggtgaaga
      541 atacgcggca gtcaaagctc aagactttgt aacaggacta aaatatgctg ctgataaaaa
      601 atcagatgct ctttaccttg ttcaagaatc aatcaaaggg ttggatgcct atgtaaaagg
      661 ggaaatcaaa gatttctcac aagtaggaat taaggctctg gatgaacaga cagttcagta
      721 cactttgaac aaaccagaaa gcttctggaa ttctaagaca accatgggtg tgcttgcgcc
      781 agttaatgaa gagtttttga attcaaaagg agatgatttt gccaaagcta cggatccaag
      841 tagtctcttg tataacggtc cttatttgtt gaaatccatt gtgaccaaat cctctgttga
      901 atttgcgaaa aatccgaact actgggataa ggacaatgtg catattgaca aagttaaatt
      961 gtcattctgg gatggtcaag ataccagcaa acctgcagaa aactttaaag atggtagcct
     1021 tacagcagct cgtctctatc caacaagtgc aagtttcgca gagcttgaga agagtatgaa
     1081 ggacaatatt gtctatactc aacaagactc tattacgtat ctagttggta caaatattga
     1141 ccgtcagtcc tataaataca catctaagac cagcgacgaa caaaaggcat cgactaaaaa
     1201 ggctctctta aacaaggatt tccgtcaggc tattgcattt ggatttgacc gtacagccta
     1261 tgcctctcag ttgaatggac aaactggagc aagtaaaatc ttgcgtaatc tctttgtgcc
     1321 accaacattt gttcaagcag atggtaaaaa ctttggcgat atggtcaaag agaaattggt
     1381 cacttatggg gatgaatgga aggatgttaa tcttgcagat tctcaggatg gtctttacaa
     1441 tccagaaaaa gccaaggctg aatttgctaa agctaaatca gccttacaag cagaaggtgt
     1501 gacattccca attcatttgg atatgccagt tgaccaaaca gcaactacaa aagttcagcg
     1561 cgtccaatct atgaaacaat ccttggaagc aactttagga gctgataatg tcattattga
     1621 tattcaacaa ctacaaaaag acgaagtaaa caatattaca tattttgctg aaaatgctgc
     1681 tggcgaagac tgggatttat cagataatgt cggttggggt ccagactttg ccgatccatc
     1741 aacctacctt gatattatca aaccttctgt aggagaaagt actaaaacat atttagggtt
     1801 tgactcaggg gaagataatg tagctgctaa aaaagtaggt ctatatgact acgaaaaatt
     1861 ggttactgag gctggtgatg aggctacaga tgttgctaaa cgctatgata aatacgctgc
     1921 agcccaagct tggttgacag atagtgcttt gattattcca actacatctc gtacagggcg
     1981 tccaatcttg tctaagatgg taccatttac aataccattt gcattgtcag gaaataaagg
     2041 tacaagtgaa ccagtcttat ataaatactt ggaacttcaa gacaaggcag tcactgtaga
     2101 tgaataccaa aaagctcagg aaaaatggat gaaagaaaaa gaagagtcta ataaaaaggc
     2161 tcaagaagat ctcgcaaaac atgtgaaata actgttgcaa aatataagaa aggatttagt
     2221 atttctcttg aatgctgaat ccttttttac atttgtaaag aaagattcta aatgtattga
     2281 cccccaaaag ttggagcctc tttttgtcag aatagagaaa atttttgtta attttacttg
     2341 tttcctattg ctttctcagc tattatttgt tatattaaaa gtataattat tttttattta
     2401 tcagggttaa gcattgcact ttcagaggaa ggagtatttt ttaaaaagga aatgtaaacg
     2461 cttgctcaaa aatgaaagga tttagaagtt tatgaataaa ggattatttg aaaaacgttg
     2521 taaatatagt attcggaaat tttcattagg tgttgcttct gttatgattg gagctgcatt
     2581 ctttgggaca agtccggttc ttgcagatag cgtgcagtct ggttccacgg cgaacttacc
     2641 agctgattta gctactgctc ttgcaacagc aaaagagaat gatgggcgtg attttgaagc
     2701 gcctaaggtg ggagaagacc aaggttctcc agaagttaca gatggaccta agacagaaga
     2761 agaactatta gcacttgaaa aagaaaaacc ggctgaagaa aaaccaaaag aggataaacc
     2821 tgcagctgct aaacctgaaa cacctaagac ggtaacccct gaatggcaaa cggtagagaa
     2881 aaaagaacaa cagggaacag tcactatccg agaagaaaaa ggtgtccgct acaaccaatt
     2941 atcctcaact gctcaaaatg ataacgcagg taaaccagcc ctgtttgaaa agaagggctt
     3001 gaccgttgat gccaatggaa atgcaactgt tgatttaacc ttcaaagatg attctgaaaa
     3061 gggcaaatca cgctttggtg tcttcttgaa atttaaagat accaataata atgtttttgt
     3121 cggttatgac aaggatggct ggttctggga gtataaatct ccaacagcta gcacttggta
     3181 tagaggtagt cgtgttgctg ctcctgaaac aggatcaaca aaccgtctct ctatcactct
     3241 caagtcagac ggtcagctaa atgccagcaa taacgatgtc aatctctttg acacagtgac
     3301 tctaccagct gcggtcaatg accatcttaa aaatgagaag aagattcttc tcaaggcggg
     3361 ctcttatgac gatgagcgaa cagttgttag cgttaaaacg gataaccaag agggggtaaa
     3421 aacagaggat acccctgctg aaaaagaaac aggtcctgaa gttgatgata gcaaggtgac
     3481 ttatgacacg attcagtcta aggttctcaa agcagtgatt gaccaagcct tccctcgtgt
     3541 caaggaatac agcttgaatg gacatacttt gccaggacag gttcaacagt tcaaccaagt
     3601 ctttatcaat aaccaccgaa tcatccctga agtcacttat aagaaaatca atgagacaac
     3661 agcagagtac ttgatgaagc ttcgcgatga tgctcactta atcaatgcgg aaatgacagt
     3721 acgcttgcaa gttgtggaca atcaattgca ctttgatgtg accaagattg tcaaccacaa
     3781 tcaagtcact ccaggtcaaa agattgatga cgaaagaaaa ctactttctt ctattagttt
     3841 cctcggcaat gctttagtct ctgtttctag tgatcaaact ggtgctaagt ttgatggggc
     3901 aaccatgtca aacaatacgc atgtcagcgg agatgatcat atcgatgtaa ccaatccaat
     3961 gaaagaccta gccaagggtt acatgtatgg atttgtttct acagataagc ttgctgctgg
     4021 tgtttggagt aactctcaaa acagctatgg tggtggttcg aatgactgga ctcgtttgac
     4081 agcctataaa gaaacagtcg gaaatgccaa ctatgtagga atccacagct ctgaatggca
     4141 atgggaaaaa gcttataagg gcattgtttt cccagaatac acgaaggaac ttccaagtgc
     4201 taaggttgtt atcactgaag atgccaatgc agacaagaaa gtcgattggc aggatggtgc
     4261 cattgcttat cgtagcatta tgaacaatcc tcaaggttgg gaaaaagtta aggatatcac
     4321 agcttaccgt atcgcgatga actttggttc tcaagcacaa aacccattcc ttatgacctt
     4381 ggatggtatc aagaaaatca atctccacac agatggtctt gggcaaggtg ttctccttaa
     4441 aggatatggt agcgaaggcc atgactctgg tcacttgaac tatgctgata ttggtaagcg
     4501 tatcggtggt gtcgaagact tcaagaccct aattgagaag gctaagaaat atggagctca
     4561 tctaggtatc cacgttaacg cttcagaaac ttatcctgag tctaaatact tcaatgaaaa
     4621 aattctccgt aagaatccag atggaagcta tagctatggt tggaactggc tagatcaagg
     4681 tatcaacatt gatgctgcct atgacctagc tcatggtcgt ttggcacgtt gggaagattt
     4741 gaagaaaaaa cttggtgacg gtctcgactt tatctatgtg gacgtttggg gtaatggtca
     4801 atcaggtgat aacggtgcct gggctaccca cgttcttgct aaagaaatta acaaacaagg
     4861 ctggcgcttt gcgatcgagt ggggccatgg tggtgagtac gactctacct tccatcactg
     4921 ggcagctgac ttgacctacg gtggctacac caataaaggt atcaacagtg ccatcacccg
     4981 ctttatacgt aaccaccaaa aagatgcttg ggtaggggac tacagaagtt atggtggtgc
     5041 agccaactat ccactgctag gtggctacag catgaaagac tttgaaggct ggcaaggaag
     5101 aagtgactac aatggctatg taactaactt atttgcccat gacgtcatga ccaagtactt
     5161 ccaacacttc actgtaagta aatgggaaaa tggtacaccg gtgactatga ccgataacgg
     5221 tagcacctat aaatggactc cagaaatgcg agtggaattg gtagatgctg acaataataa
     5281 agtagttgta actcgtaagt caaatgatgt caatagtcca caatatcgcg aacgtacagt
     5341 aactctcaac ggacgtgtca tccaagatgg ttcagcttac ttgactcctt ggaactggga
     5401 tgcaaatggt aagaaacttt ctactgataa ggaaaagatg tactacttca atacgcaggc
     5461 cggtgcaaca acttggaccc ttccaagcga ttgggcaaag agcaaggttt acctttacaa
     5521 gctaactgac caaggtaaga cagaagagca agaactaact gtaaaagatg gtaaaattac
     5581 cctagatctt ctagcaaatc aaccatacgt tctctatcgt tcgaaacaaa ccaatcctga
     5641 aatgtcatgg agtgaaggca tgcacatcta tgaccaagga tttaacagtg gtaccttgaa
     5701 acattggacc atttcaggcg atgcttctaa ggcagaaatt gtcaagtctc aaggggcaaa
     5761 cgatatgctt cgtattcaag gaaacaaaga aaaagttagt ctcactcaga aattaactgg
     5821 cttgaaacca aataccaagt atgccgttta tgtcggtgtc gataaccgta gtaatgccaa
     5881 ggcgagcatc actgtaaata ctggtgaaaa agaagtgact acttatacca ataagtctct
     5941 cgccctcaac tatgtaaaag cctatgccca caatacacgt cgtaacaatg ctacagttga
     6001 cgatacaagt tacttccaaa acatgtacgc cttctttaca actggatcgg acgtatcaaa
     6061 tgttactctg acattgagtc gtgaagctgg tgatgaagca acttactttg atgaaattcg
     6121 tacctttgaa aacaattcaa gcatgtacgg agacaagcat gatacaggta aaggcacctt
     6181 caagcaagac tttgaaaatg ttgctcaggg tatcttccca tttgtagtgg gtggtgtcga
     6241 aggtgtcgaa gacaaccgca ctcacttgtc tgaaaaacac gatccatata cacaacgtgg
     6301 ttggaatggt aagaaagtcg atgatgttat cgaaggaaat tggtcactca agacaaatgg
     6361 actagtgagc cgtcgtaact tggtttacca aaccatccca caaaacttcc gttttgaagc
     6421 aggtaagacc taccgtgtaa cctttgaata cgaagcaggt tcagacaata cctatgcttt
     6481 tgtagtcggt aagggagaat tccagtcagg tcgtcgtggt actcaagcaa gcaacttgga
     6541 aatgcatgaa ttgccaaata cttggacaga ttctaagaaa gccaagaagg caaccttcct
     6601 cgtgacaggt gcagaaacag gggatacttg ggtaggtatc tactcaactg gaaatgcaag
     6661 taatactcgt ggtgattctg gtggaaatgc caacttccgt ggttataacg acttcatgat
     6721 ggataatctt caaatcgaag aaattaccct aacaggtaag atgttgacag aaaatgctct
     6781 gaagaactac ttgccaacgg ttgccatgac taactacacc aaagagtcta tggaggcttt
     6841 gaaagaggcg gtctttaacc tcagtcaggc cgatgatgat atcagtgtgg aagaagcgcg
     6901 tgcagagatt gccaagattg aagccttgaa gaatgctttg gttcagaaga aaacggcttt
     6961 ggtagcagat gactttgcaa gtcttacagc tcctgctcag gctcaagaag gtcttgcaaa
     7021 tgcctttgat ggaaacttat ctagtttatg gcatacatca tggggcggag gagatgtagg
     7081 caagcctgca accatggtct tgaaagaacc aactgaaata actggacttc gttatgttcc
     7141 acgtggatca ggttcaaatg gtaacttgcg tgatgtgaaa cttgttgtga cagatgagtc
     7201 tggcaaggag cataccttta ctgcaactga ttggccagat aacaataagc caaaagacat
     7261 tgactttggt aagacaatta aggctaagaa aattgtcctt acaggtacta agacttacgg
     7321 agatggtggc gataaatacc aatctgcagc ggaacttatc tttactcgtc cacaggtagc
     7381 agaaacacct cttgacttgt caggctatga agcagctttg gctaaggctc agaaattaac
     7441 agacaaagac aatcaagagg aagtagctag cgttcagtca agcatgaaat atgcgacgga
     7501 taaccatctc ttgacggaaa gaatggtgga atactttgca gattatctca accaattaaa
     7561 agattctgct acgaaaccag atgctccaac tgtagagaaa cctgagttta aacttagctc
     7621 tttagcttcc gatcaaggta agatgccaga ttataagcaa gaaatagcta gaccagaaac
     7681 acctaaacaa atcttgccag caacaggtga gagtcaatct gacacagccc tcttcctagc
     7741 aggtgttagc ctagccctat ctgctctctt tgtagtaaaa acgaagaaag actagtattt
     7801 agtaaaacat cttaacaaga ttacggaagc agtctctatc ttttccaatg aggtttatag
     7861 tacagaaaaa gcctgagaag atgtcttctc aggcttttgt taagcacata aatacaatag
     7921 tgctatgaaa aaatcaccca gaaaaa
//
LOCUS       DBEJZV010000059         7906 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.59, whole genome shotgun sequence.
ACCESSION   DBEJZV010000059 DBEJZV010000000
VERSION     DBEJZV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.59"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(43..2589)
                     /locus_tag="ACL3S0_002005"
     CDS             complement(43..2589)
                     /locus_tag="ACL3S0_002005"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGR1312854.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLAAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(2712..3152)
                     /locus_tag="ACL3S0_002006"
     CDS             complement(2712..3152)
                     /locus_tag="ACL3S0_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGR1312855.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQIHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(3127..3996)
                     /locus_tag="ACL3S0_002007"
     CDS             complement(3127..3996)
                     /locus_tag="ACL3S0_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGR1312856.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYCFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGINDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(3974..4474)
                     /locus_tag="ACL3S0_002008"
     CDS             complement(3974..4474)
                     /locus_tag="ACL3S0_002008"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR1312857.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(4485..5183)
                     /locus_tag="ACL3S0_002009"
     CDS             complement(4485..5183)
                     /locus_tag="ACL3S0_002009"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGR1312858.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(5176..5412)
                     /locus_tag="ACL3S0_002010"
     CDS             complement(5176..5412)
                     /locus_tag="ACL3S0_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGR1312859.1"
                     /translation="MTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTIEQNGLALEMT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(5510..6436)
                     /locus_tag="ACL3S0_002011"
     CDS             complement(5510..6436)
                     /locus_tag="ACL3S0_002011"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGR1312860.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(6511..7326)
                     /locus_tag="ACL3S0_002012"
     CDS             complement(6511..7326)
                     /locus_tag="ACL3S0_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312861.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLVGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVVTILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(7330..7650)
                     /locus_tag="ACL3S0_002013"
     CDS             complement(7330..7650)
                     /locus_tag="ACL3S0_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR1312862.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         2340 a         1810 c         1390 g         2366 t
ORIGIN      
        1 tttacatgag atagctgagt tttcttttta ttttaggctt atttatgcat ttccgtattg
       61 aagaacaact gcttcgactg cagctttttc acggctaatc aagtcaacac gcgctgcaat
      121 ttccttgatt cccataccga tgttacggct aagagcaagg tcagaaagtt gcggttcaaa
      181 gaactccttg tattccgcca agcgttgctg agtcttaaat acatgagcag gaaggataac
      241 aaagctatca aagctcatat ctcctccaag ggctgcctta atccaagccc agttttcacg
      301 cgcccaagac caagctgttt tctgagttgc ttgatgagct aggaattggt aataccaagc
      361 agacaagtcc tgtggtttga ccacaaattt gtccttccaa gaagtaatca agttttggat
      421 attatccgca tctgtactgt atgcaagagc tgctgccaac tggcgtttaa agacagcatc
      481 tgttgcgtga gtataagtat caagataaag tgctaacaag tctttagtct catgatgttt
      541 catctcatta atcagaactt gtgaacgaat agctgctggg agtcctgcaa gattctcctt
      601 gtgtgttgcg aagatttggc tagcgacttg actagcttct gcatcatttg agcgaatcat
      661 catcgaaaca gccagctgac gaaccaattc atcctcatct gattctccgt ctttagcttc
      721 aaaaccaaga cggtcatagt tatgacgagc caatttagca accagtcctt tgaaggctgt
      781 ttcagcatcc gttccttcat caataaagcg ctcaagggct gaaatcactt gagaaacagc
      841 tgaaaccacc agataagact cttccttagc aagtttatca agaactggaa gcaagtctgc
      901 ataagaaatg tgccctgcct cagccaacaa acgacgttct tgaacaattt gcagtttgct
      961 tgtgttatca agtgtctcta gctcagcaag aacagctgct aacaagtctc cttgatagtc
     1021 ggtaatatag tgggcagtat tttcagtgtt gagacgaaga gctccttcat tttcagcaag
     1081 aagagctgcg tagccaggga tttcgatact ttcagtttcg agtgtatcag gcaagccttt
     1141 ccagttgcta ttgaggggca ccacccagag acggttcttg tcttcgttct caccgatgaa
     1201 gaattgtttt tgtgaaatct tcaagacatc attttcaact ttgacagtaa gaactgggta
     1261 accaggctgt tccaaccaag aatccatgaa ggctgcgaca tcacgtcctg acgcttgacc
     1321 aagggcatcc caaagatcac taccaatggt gttgctgtat tggtgttttt caaagtaggc
     1381 atgcaaacct ttagcaaaat cagcatctcc tagccaacgg cgaagcatgt gcatgagacg
     1441 gcttcctttg gcatagacga tagcgccgtc aaagagtgta ttgatttcat ctggatgttt
     1501 aacttcgacg tggacagact gaacgccatc agtagcgtca cgttcaagag caagaggtac
     1561 tccacctgtt tggaaatctt caaagatatt ccagcttggt tcgatggtat ccacacagac
     1621 gtattccatc atattagcga aactttcatt gagccaaagg tcatcccacc atttcatagt
     1681 cacgaggttc ccaaaccatt ggtgagccaa ttcatgggcc acaacaaggg caacttgttg
     1741 acggctagca aatgtagagt tctcatcgac aaccaagtaa acttcacggt aagtcacaag
     1801 accccagttt tccatagcac cagctgagaa gtcaggaagg gcgatgtgga gagattgagg
     1861 aattgggtac ttaactccat agtaatcttc gtaaaactcg atagagcgaa cagcgatatc
     1921 cagtgagaaa tcaagatttg aaagtggatg tgctttggtt gagtagacac ctaccagggt
     1981 accattttta gttttagcgg tcaccccttg caaatcacca gcaacaaagg ccaacaagta
     2041 agaagacatg cgaggtgttg tctcaaactt ccagatacct gtttccttac ggttttcaac
     2101 atcgatttct ggcatgtttg acaaggccaa ttcaccttct gcttggtcaa agcgaagaga
     2161 gaggtcaaaa gttgctttgg cttcaggctc atccacacat gggaaagctt cgcgcgcaaa
     2221 atggctctcg aactgagtag acaagacctc cttcttgact ccatcaactg tataataaga
     2281 agggtaaatc cctgtcatgt tgtctgtaat tttaccagaa aaggcaagaa ccaattcaac
     2341 ttgaccagcc tcagccaatt cgatatgaag ggcttcattg tcatggtcaa ctgtaaatgg
     2401 acgagcttga cctgcaactt ctacagaggt gatttccaag tctttttggt ggagggagat
     2461 gcggtcactc tgtgcttgac cagtgatggt cactttccca gaaaaagtct tggtctcacg
     2521 actcaaatct aaaaataaat cataatgttc aggaacaaat tgcttaataa aatgttcaac
     2581 tgcttgcata gttttctcct attctaagtt taagagctgc tgctcttctt caaacaaact
     2641 tattatatca tattttgctt gagaaaaaag gattggacag cgatttccaa aactttcttc
     2701 cttctaatag tctacagtgg gtagaccttg cgaaattctt ctaaaacaac cttgctttca
     2761 ggtgtaaaag tcagccctac ttcacccaaa cagtctgtga aaaagtcctc atgaatctgg
     2821 cgccaatagg caagtgattt gtctccctca ccttccttaa aggcatgttg cgcagaaact
     2881 tgattgaaga gttcaacaga aacctttgta atttcgacaa tgcagacaga ctgattttga
     2941 ctatctaaaa tgacatcgaa ggtccctact tggggaagtg gttcgtcttc tagtacatag
     3001 aggtcatagg ctgatgctgt tgctgtcttt tctcctttaa acaccaaatc cgctaaaagg
     3061 tctggttcaa ctccaaaagc ccaagcatcg atttcatctc cgatcaaagg attgatttgc
     3121 ttgtatttat tccacatttc ttgcggtatc atgggtactc ctttgtaatt ttttactttc
     3181 ttcttttatg tgtttaagat gatctggatg gtcaatctct aaatcaaaaa tctctggaat
     3241 agaactgtag tggataatgc acttgatacc caactgattc attttttgta tgaaagaagt
     3301 attcagatag cctgctacag caaaattaat cttgttcttt cttgctttat cctgcatatc
     3361 tcttagcata tctaacatta ttggactttc cagatcatgc cattgactgt ttctcatagt
     3421 cgcaaaaaca aaggaagtca aatcatttat tccaactaca atctttgaaa tgcccgtttc
     3481 cagtatacta gataagtcaa aatacgctga cggtaattca atcatcgttc cgactttccc
     3541 agtaaagcca tactgacgca atactgtaat agcttgtttt aattggtcgg catcattgac
     3601 aaaaggaaag ataagagaca gattggggtt ggtttgataa acttctgtaa cgacatgtgc
     3661 ttcagcctga aattcatcca aacacgccag taaacgcctg gttcctctat agccaaacaa
     3721 gggatgccct tcgtcaaaaa actctttagt ccccactaaa caattggctt ctgtattcgt
     3781 taattcagta aaacaatacc aaacttcttc atctgagtac agggagcaga tagtctctag
     3841 ataatctttt acaaattgct gacaacttgc taatatgatg ttttgattaa gctctctcaa
     3901 caaatattcc ccacgaatca tgccgacgtg gtgaaatagt tgaggataaa ttttttcaag
     3961 aattttttcg ccactaaggg caagttgatt tctcatcatt caccttccaa ttcatgtaag
     4021 aagtcttgtc cagttctgga aatcctaata attcagactt aaccttcaag actaatggcg
     4081 atgcattttc ttctgtaatc tcttgaatat ccatccaaat atatccaagt gaatcattcg
     4141 caccatcaga cacagcttcc gaagtcgtaa cttgaggtgc actctcattc atttcaacat
     4201 catacaaggc catgacatgg tgaaccataa aatttgttaa ctcttctctg acgaaaacat
     4261 cgtagattcg aggattagag tagcttctaa cagtaaatcc cgtctcttcc ataacttctc
     4321 tagtcagcgt ttccgtcagt ccttcaccaa gttgctgact gcctccaggt agatcatacc
     4381 gatgttgata agggcctctc gctttttcaa tgcagagtaa cttcccattt tctaagcaaa
     4441 cagcgtagac tccaaagtgt tttttgattt ccatccaact cctcctactt caaagaccag
     4501 ccaccatcta ttgtcaagat ttgtccttgc atggcgctcg cttttccact tgctaaaaaa
     4561 agactaagct ctgctatttc ctctggctca atccagcgct tgattggggt ttcactagcc
     4621 acccagtcag ccaaaccacc tggttcaaaa tccgcagcgg tcatagctgt cttgactgct
     4681 cctggagcga tcccaaagac ctgaatccca gcttcagcat agtctagagc caactgcttg
     4741 gtgaagccag ccaaggcatg cttggatgaa gtataggcgt gaccacctcc acctgctagg
     4801 ctagaagcaa tggaacacat attgatgatg attccctttt tattttccag catttgtgtc
     4861 aaataatacc gagtcaactc tactggaata atgtagttga tttcaaaaat ctcttgaatg
     4921 tcctgcgccg tttgttccaa cagtggtttg taatcatcca aaactccggc agtattacac
     4981 aaaacatcca cctgagggca ccagtcaaaa ataggttcca agtccaaggt caaatctctc
     5041 tgtaaaaagt gaaaatcacc ctctaagagt ggcttttcac cttggtcaac tccataaact
     5101 tgatagccct tctctaaaaa gaggcgagct tgagccaatc cgatccctga actcactcct
     5161 gtaatgagta cacgtttagt catgcacttc tacccaatcc gttgccaaaa catcacaagc
     5221 tgtcgggctc cacatggaaa aaccttctcc ttctccagac acgttgatta ggaaataagg
     5281 tgtcatttca agtgcaagcc cattttgctc gatggtatca aagagttgga catagttttc
     5341 cgcacctccc caaccagttc gtacatattt tctcttagcc tttaacccag gcaggatctc
     5401 ttcaaatgtc atgtttttct cctttaattc tacattcttc atttaattat aacaaaaaaa
     5461 ccgctttaaa acggcttttt gactgtgatt tatttacatc ttcttctact tacggcaaat
     5521 tattccctgc agcaagataa atttcatacc attcttttct tgttaagcta aagtttgccg
     5581 cttggctaac ttctctcaag tgcttaggat ttgtggtacc tacaactgcc tgcatttttg
     5641 ctggataacg caatatccaa gaaatggcaa tagttgaaga ggttactcca tatttaatag
     5701 ctaaacgatc aagtacttga tttaaagctt gaaatttctc atttccaaca aaattccctt
     5761 taaaataccc gaattgtaag acagaccatg cttgaatgac cacatcgtgt aatttgcaat
     5821 attcaaaaat gctgccatct cgcatagctg cttgactatc ttccatatta acatgaaaag
     5881 ctgattcaaa tcctggagta aaagccgcac tcaattgtag ctgattaaca gctaacggct
     5941 gcttgacatc ttttttaagc aactccatca tcataggatt ttgattagaa actccaaaat
     6001 ctcgaacttt accttgttta taaaggagat caaaggcttc tgctacttgg tcagattcca
     6061 tcaaagcatc tggtcgatga aggagcaagc tatctagatg atcaatcttc aatctttgca
     6121 aaataccgtc tactgatttt ataatatagt ccttagaaaa atcaaaatag gtaaattctt
     6181 caatgcgaat gccacatttg gactgaatcc acatcttttc tcttaaatct ggacgatttt
     6241 ttaggacaag acctaacagt tcttcacaac gaccacgacc ataaatatca gccaagtcga
     6301 aggcattgat tccaacagaa agtgctgttt ctacaagctc ttcaacttct tttacagact
     6361 tatcttttat tctcatcatt ccgagaacaa tttctgataa ttctttgtca tcttgaccaa
     6421 gagttatgta tctcatcaaa tttttctcct ttaatttcta acattcttcc cttcattata
     6481 acaaaaaacc gctttgcaac ggctttttga ctatacttca ctccatttta tcttcttaaa
     6541 cccacggaac aagacaaaga ttccaataaa gaggacagct aaaggaataa cttttgtaag
     6601 gaaaacattt gaaattccca tccactcata ataacggagc agagaaccca ccacaagatg
     6661 ggcaataatc atactgacaa atggacgaaa gaccgcttct ttccaattcc aaataccgat
     6721 aactagcgaa atcgtaaaga cagacaaact atcccaggga gccggaatat aaaaggctcc
     6781 ttcttgtatg aagcttgcca ttcctacata tcctaaaaca actagaagaa ctatagtccc
     6841 aacaacaatg taagtgccaa ttttcatttt aggagaatct tggactaaac ttcttcgtaa
     6901 aattgtgacc acaagtccaa atccaatcag aaaaataaga agttgcccta aaaatgtgag
     6961 caaattgact gttaagagag gacctttaga aaaatcactt agtagttgat aataacgtaa
     7021 taccgccagg acaagaattg gcgtcaaaag ggactctttg atagaactgc gaggtgctcc
     7081 cttgagaatc tctttcatta tttttttagg attcttacct agataatcct ctgcactcat
     7141 gccatctcgt tctgcttctg agaaatctag catcatcaaa tagatctgct ctctgagata
     7201 gtcttcatca tagagaaatc caacaagatt aaaactttcc cacaactcct caaaatactt
     7261 ttgattctcc tcagaaaact catgtagcaa agcgcttgtt tcttcgtaat acttcatttt
     7321 cttcatggtt taacccccat tcttaatccc ttctactttt tgactcaaat cgtcccattg
     7381 ttgccaaaag actgagacac gctcttctcc ttctttcatt aatgaaaaat acttccgatc
     7441 tggaccatct ggcgacgggc gcatgtcgcc tcttatccat tgattttttt ctaacttttg
     7501 caacaaagga taaatagttc ctggaacgat agtatcaaat ccagcctctc gcaaagtctg
     7561 aaccaactca taaccatacc gctctttttg accaatcata tccaagacac aaccttcaag
     7621 aacacctttt aatagctgag tttctttcat cacttctccc ttctaatcta ttttgtaata
     7681 cctactagta acttcaccta tagtatatca cttctacact agtttgtaaa gcataatagt
     7741 taatactctt cgaaaatctc ttcaaaccac gtcatcgtcg ccctaccgta tgtatggtta
     7801 ctgacttcgt cagtttcatc tacaacctca aaaacatgtt ttgagctgac ttcgtcagtt
     7861 tcatctacaa cctcaaaaac atgttttgag ctgacttcgt cagttt
//
LOCUS       DBEJZV010000060         7777 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.60, whole genome shotgun sequence.
ACCESSION   DBEJZV010000060 DBEJZV010000000
VERSION     DBEJZV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.60"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(52..3894)
                     /gene="spuA"
                     /locus_tag="ACL3S0_002014"
     CDS             complement(52..3894)
                     /gene="spuA"
                     /locus_tag="ACL3S0_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGR1312863.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATSPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDETGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLREEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRKESVENSSKENISATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            4311..4724
                     /gene="rpsL"
                     /locus_tag="ACL3S0_002015"
     CDS             4311..4724
                     /gene="rpsL"
                     /locus_tag="ACL3S0_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGR1312864.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            4744..5214
                     /gene="rpsG"
                     /locus_tag="ACL3S0_002016"
     CDS             4744..5214
                     /gene="rpsG"
                     /locus_tag="ACL3S0_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGR1312865.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            5639..7720
                     /gene="fusA"
                     /locus_tag="ACL3S0_002017"
     CDS             5639..7720
                     /gene="fusA"
                     /locus_tag="ACL3S0_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGR1312866.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
BASE COUNT         2130 a         1561 c         1737 g         2349 t
ORIGIN      
        1 ttaatccccc gagctataat gcttggggga tttttctata ggagggctag cttagttctc
       61 ttttttattt tttagtaaga aaccgagacc aaggagcgca aggaggctga ttcctgcaaa
      121 taggagtttg ttttcgtttt tgattcctgt atttggaagt tcagcttgtc tatctggggt
      181 tgcagatata ttttccttgc tagagttttc taccgattct tttcgaaccg cttcttttac
      241 agatgatgct tgtgcttctt gtgctggttg ttcagcttgt gaatcagctg tagcttggct
      301 aggtttattt tccgcatcag ctactttggc atctggttta gtagaatcag gtctagcttc
      361 tggagctggg tcttgatgtg cagggtgaga agcttcattt tgatgttcag gcttggaagg
      421 ggttgagtct ggtttctctt ctgcagttga ctcatggcta gttccatttt gagagactcg
      481 aagaacagta gctgtaaggg cattcaattt caagcctttt tcagtccatt caagtccttt
      541 cgggttggca attccgactg atcctgcttg gttttcatct gccaaaactt ccgcatttct
      601 tagatgtgca aaggcagttc ccaaattaaa ttcgcgagct ttttcatccg cattgacaaa
      661 gactgcgtag atatcgccgt ttggagcagt gatttggtag ccaatcacta catcctcttt
      721 ttccacacca ttttggcctg ggacagtgat gaggtggaca cggtctttga tatcttggag
      781 actcttaagt cggaaggcat ctgtagattg acgaagggca atcaaacctt tcatatagtc
      841 acggctcttg acattttcag gataagcttt accatctgta gccttagtcc agtcaaactt
      901 gttgactgcg tcgctagaat cgtaagaatc atggatgaag taaggatagt caaatgggtt
      961 gccgtcctta tcacgcaaca agtgagattt gtttggaacc ttatcctctg ctactggagt
     1021 cttgtaggct gggtcacgga attgtttagt acgtccatat tcctgaccgg agtggataaa
     1081 tggagttcct tgagctgtca agaccatgag atttccaagt cgtaaacgac ggtggatttc
     1141 agcatagttc tcagccttgc ttgggtcttt tttgatagac tgggcaatga tgtcaaagag
     1201 ggtcaagtta tcatgggctg cgatgtattg gatgacatct ccagggctgt cagcttcaaa
     1261 gttagttggt tgagcaatga gatttttaaa gatggtgttg acatcacgct tgccacctgt
     1321 gataaaggca ggttgacctt cgtttggata accagatttg aggttgttac ggatgtcatc
     1381 tgaaaagaca gcgacagtat cggtatgttt catccaatct tggtcagcag ctttagtagg
     1441 catgttttca tcaccggcat aggttctcca accttcgcct aacatgatta gatttggatt
     1501 gagggcgcgt gcagccttgt aagcttcttc gatagaagcg gcgtcatggt ctcccatcat
     1561 atcgaagcgg aagccatcca ctttgtaggt atcaactagg tatttgatag agtcaactag
     1621 gagccgtttg gtcatatggt gggttgtccc caagcgtcca ccaccaaagc tagttcgagg
     1681 tgtgccatcg gcatccataa agtggtagta gtttggctct aggtcttcaa agatatcgac
     1741 tttggctgtg tggttataaa cgacatctag gatagctccc ataccacgtt tgtggatttc
     1801 gttgatgagg tttttaaatt ctgcgattcg tttttctgga ttcttaggat cgcttgagta
     1861 cataccagtc aaggagaagt agttttgagg gtcatatccc cagttgtagt tgctgttgct
     1921 tgaagcatag tcagacaagc gttcatggtt tttcaattca ttgacaaagt agtaagacaa
     1981 gactggaagg agctggatat gggttacacc caagtctttg agatagtcta gtttttcaat
     2041 gaaggcttca aaagtcccaa atggtttggt caagtctttt gcaatggcag gatctgaagt
     2101 gaagtcacgc acatgagctt cgtagataac ggcgtcttca cgagtcttga aattgtgaat
     2161 cttaccataa gtcaagtctt gaggtccgag tttagctgga tctacaaagg cggctttagc
     2221 cactttatgg gcatcgtcaa tcttggcatc gtcgctattc caagcagcaa gagatttagc
     2281 gtaaggatcg agtgcaagaa cagttttacc ttgacgctcg atttggtatt gataatagta
     2341 gccagtgaaa tctgtgattc cgagtttgtt tgtgctgtct agagtttgtt tccaagttcc
     2401 tctttcccct ttttcgagag cgacagttcc aactactttg tcagggtcat tcttgtcgta
     2461 gacaacaaca gaaaccttat cagcacttgg tgaccaaagg gtcaaatcaa cttgttttcc
     2521 ttcttctctt aggtcagctc ccagtttgcc atcatagctg tatgtctcat ctttcaggcg
     2581 ccagcttgtt ttggtagtga attgatcgga attgtagcta acagtataag gatgttttgt
     2641 gtcagagaaa tctccgctgt aggtcacttt cttaccagtt tcatcgattg caacatcggt
     2701 aatagttacc ttgtttccta ggtgattagt gatgttggag tgtttgagga tatcttcttt
     2761 tttagcaccg acaagtgttg aaaagctact ttcaatgcta gaagtgccta cgtgttgggc
     2821 tcctgtcata cggatatcat ggacatagta tggatttgtg taaatcgatt catcatcgtc
     2881 ttttaggaaa atttggctat gatttttcaa atctgtgaac ttataatttt ctttacggat
     2941 tttcacgtcg tctccttgtt tgctctcatc tagtaataaa aatccaaatt ctcttgcggc
     3001 ttcattaaga ggaatgtcga tatagcggcc atatttgcct gtagccgtaa agtctgttcc
     3061 gtcaggccat tgagcgctac ttggattttt tacatctccc cagtaccaga gagatttctt
     3121 gtcatagttg ccatctgtgc ggtagtagtt gacgcgaaca gttcctgcag gctgtggctc
     3181 gtaagagaaa accttgtaat cttggtctaa ccaagcttcg ttcatttttg gaactagttt
     3241 ttctacagat ttatcgccgg ttagattttt tccagctgta ttgttgatga ggaagctaat
     3301 tttcttggct tgttctccct ttaatttgac atctaggtaa tagccgtagt catctttctt
     3361 ggcatccttg aaggacaaag ctccgtttgg ccagttttca gatggttttt caacatcgtc
     3421 ccaagtccat agtccttgag catccttgtt ttcttcagga agttttttga catggatacg
     3481 gaagtagtta tcttcgatgg gctcttctgc cttagtttca gttgttactg gactagtaga
     3541 agtagttggc tcacttgaac gatcttgtcc agtttgtggt gctggatcgg ctgggcttgt
     3601 agcaggtttt tcttctgttt tctctaggga agcgtttgca tttctaggtg aagaaatatc
     3661 actttcgttc ttaccagagc cagctgctgt atcagtaaga ggttgagcaa gggtggttgt
     3721 atttctgttg ttgggttcgt tagtggttgg tgtactttcg tcggatgaga tagttggtgt
     3781 agccatggca agcaagacaa ggcttgcgcc gataaggaca gaaccagttc catttttgag
     3841 ggaacggatg ctgtagacca tttttttctc agtgtgagat ggtgtttttc tcataatgat
     3901 tctccaatca ataaatttct atatcagtat agcatgtagt aaaacaatat gcaagcgttt
     3961 tctttgattt gtgaaaaaaa ttcctacttt tgagaagttt tctgtactat tttatatatc
     4021 agtataaatg acggagataa aaatgtcaca taagccaagc cgtattatta ggaagatgat
     4081 gtgttcccag ctatttttat tcagaaattg atctctaaca ttaccaataa aaatgaaaaa
     4141 tatcttgaca agcaagggaa aattttgtta caataataga cggtactttt tacttttggt
     4201 ctctcaagag tgtacaggga cgtgctgaca aatgttgcaa aagtacacac agatgatatc
     4261 tgtcaccaag tgtatcatca ccaaaaataa aaaaacacag gagaatgtag atgcctacaa
     4321 ttaaccaatt ggttcgcaaa ccgcgtaaat caaaagtaga aaaatctaaa tcaccagctt
     4381 tgaacgttgg ttacaatagt cataaaaaag ttcaaacaaa cgtttcttca ccacaaaaac
     4441 gtggtgttgc aactcgtgtt ggaacaatga cacctaaaaa acctaactca gcccttcgta
     4501 aattcgctcg tgtacgtttg agcaacctta tcgaagttac tgcctacatc ccaggtatcg
     4561 gacacaactt gcaagagcac agcgtggtgc ttcttcgcgg tggacgtgta aaagaccttc
     4621 caggggtacg ttaccatatc gtccgtggtg cacttgatac tgcaggtgtt aacgatcgta
     4681 aacaaggccg ttctaaatac ggtactaaac gtccaaaagc ataaggaaag gggataaaga
     4741 gaaatgagtc gtaaaaatag agctccaaaa cgtgacgtat tgccagatcc gctatacaat
     4801 tcacaactag ttactcgtct tatcaaccgc gttatgcttg atggtaaacg tggtactgct
     4861 gcttcaatcg tttacggtgc ttttgagcaa atcaaagaag ctactggcaa cgatgcactt
     4921 gaagtatttg aaacagctat ggaaaacatc atgcctgtac ttgaagtacg tgcacgtcgt
     4981 gttggtggtt ctaactacca agtcccagtt gaagttcgtc cagaacgtcg tacaacactt
     5041 ggacttcgtt ggttggtaac aatcgctcgt cttcgtggtg aacacacaat gcaagaccgt
     5101 cttgcaaaag aaatcttgga tgctgctaac aacactggtg cagcagttaa gaaacgtgaa
     5161 gatactcacc gtatggctga agctaaccgt gcattcgcac acttccgttg gtaagatagg
     5221 atgcgaaagc gttaagaaag tcccagagaa aatagggaat cgaagcaggt tgcggttgca
     5281 accaatgaga ttcatctttt tctccagact tttagcttga gctcaactaa atcatgatgc
     5341 taggcacggt aaggatgcaa ggtgaaaata ggaaactgac gcagtattca acgaatacaa
     5401 ggagttttat ctttttcacg cagcatcccg ttccagctca catcggctaa ctaactttag
     5461 cctgggttca aattagctaa atcgattagt attagctata actcagctta ccatctcgta
     5521 agttgaaacc aacaatagca tgaaaacatt gagaacgggt aggtcctgcc tatccgtttt
     5581 tattaaaatc gtgttataat agaatagaaa tcaaaaataa ataggagaaa caaacctcat
     5641 ggcacgcgaa ttttcacttg aaaaaactcg taatatcggt atcatggctc acgtcgatgc
     5701 cggtaaaaca acaactactg agcgtattct ttactacact ggtaaaatcc acaaaatcgg
     5761 tgaaactcac gaaggtgcgt cacaaatgga ctggatggag caagagcaag aacgtggtat
     5821 cacgatcaca tctgctgcga caacagctca atggaacaac caccgcgtaa acatcatcga
     5881 cacaccagga cacgtggact tcacaatcga agtacaacgt tctcttcgtg tattggatgg
     5941 tgcggttacc gttcttgact cacaatcagg tgttgaacct caaactgaaa cagtttggcg
     6001 tcaagcaact gagtacggag ttccacgtat cgtatttgcc aacaaaatgg acaaaatcgg
     6061 tgctgacttc ctttactctg taagcacact tcacgatcgt cttcaagcaa atgcacaccc
     6121 aatccaattg ccaatcggtt ctgaagatga cttccgtggt atcattgact tgatcaagat
     6181 gaaagctgaa atctatacta acgaccttgg tacggatatc cttgaagaag acatcccagc
     6241 tgaatacctt gaccaagctc aagaataccg tgaaaaattg attgaagcag ttgctgaaac
     6301 tgacgaagaa ttgatgatga aatacctcga aggtgaagaa atcactaacg aagaattgaa
     6361 agctggtatc cgtaaagcga ctatcaacgt tgaattcttc ccagtattgt gtggttcagc
     6421 cttcaaaaac aaaggtgttc aattgatgct tgatgcggtt atcgactacc ttccaagtcc
     6481 acttgacatc ccagcaatca aaggtattaa cccagataca gacgctgaag aaactcgtcc
     6541 agcatctgac gaagagccat ttgcagctct tgccttcaag atcatgactg acccattcgt
     6601 aggtcgtttg acattcttcc gtgtttactc aggtgttctt caatcaggtt catacgtatt
     6661 gaatacttct aaaggtaaac gtgaacgtat cggacgtatc cttcaaatgc acgctaacag
     6721 ccgtcaagaa atcgacactg tttactcagg tgatatcgct gctgccgttg gtttgaaaga
     6781 tactacaact ggtgactcat tgacagatga aaaatctaaa atcatccttg agtcaatcaa
     6841 cgttccagaa ccagttatcc aattgatggt tgagccaaaa tctaaagctg accaagacaa
     6901 gatgggtatc gcccttcaaa aattggctga agaagatcca acattccgcg ttgaaacaaa
     6961 cgttgaaact ggtgaaacag ttatctcagg tatgggtgaa cttcaccttg acgtccttgt
     7021 tgatcgtatg cgtcgtgagt tcaaagttga agcgaacgta ggtgctcctc aagtatctta
     7081 ccgtgaaaca ttccgcgctt ctactcaagc acgtggattc ttcaaacgtc agtctggtgg
     7141 taaaggtcaa ttcggtgatg tgtggattga atttactcca aacgaagaag gtaaaggatt
     7201 cgaattcgaa aacgcaatcg tcggtggtgt ggttcctcgt gaatttatcc cagcggttga
     7261 aaaaggtttg gtagaatcta tggctaacgg tgttcttgca ggttacccaa tggttgacgt
     7321 taaagctaag ctttatgatg gttcatatca cgatgtcgac tcatctgaaa ctgccttcaa
     7381 gattgcggct tcactttccc ttaaagaagc tgctaaatca gcacaaccag ctatccttga
     7441 accaatgatg cttgtaacaa tcactgttcc agaagaaaac cttggtgatg ttatgggtca
     7501 cgtaactgct cgtcgtggac gtgtagatgg tatggaagca cacggtaaca gccaaatcgt
     7561 tcgtgcttac gttccacttg ctgaaatgtt cggttacgca acagttcttc gttctgcatc
     7621 tcaaggacgt ggtacattca tgatggtatt tgaccactac gaagatgtac ctaagtcagt
     7681 acaagaagaa attattaaga aaaataaagg tgaagactaa tccgtcctca ctctagaagg
     7741 aagtcactta gtggcttcct tttgtcttta gaaaata
//
LOCUS       DBEJZV010000061         7771 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.61, whole genome shotgun sequence.
ACCESSION   DBEJZV010000061 DBEJZV010000000
VERSION     DBEJZV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7771
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.61"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..1086
                     /gene="ald"
                     /locus_tag="ACL3S0_002018"
                     /pseudo
     CDS             1..1086
                     /gene="ald"
                     /locus_tag="ACL3S0_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(1387..1713)
                     /locus_tag="ACL3S0_002019"
                     /pseudo
     CDS             complement(1387..1713)
                     /locus_tag="ACL3S0_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(1716..2216)
                     /locus_tag="ACL3S0_002020"
     CDS             complement(1716..2216)
                     /locus_tag="ACL3S0_002020"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1312867.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYAVVIA
                     EQSLED"
     gene            complement(2396..3364)
                     /locus_tag="ACL3S0_002021"
     CDS             complement(2396..3364)
                     /locus_tag="ACL3S0_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGR1312868.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(3450..3665)
                     /locus_tag="ACL3S0_002022"
     CDS             complement(3450..3665)
                     /locus_tag="ACL3S0_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGR1312869.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDAIWQEYLEH"
     gene            complement(3674..4528)
                     /gene="cvfB"
                     /locus_tag="ACL3S0_002023"
     CDS             complement(3674..4528)
                     /gene="cvfB"
                     /locus_tag="ACL3S0_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGR1312870.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(4588..5145)
                     /gene="frr"
                     /locus_tag="ACL3S0_002024"
     CDS             complement(4588..5145)
                     /gene="frr"
                     /locus_tag="ACL3S0_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGR1312871.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKREKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(5154..5891)
                     /gene="pyrH"
                     /locus_tag="ACL3S0_002025"
     CDS             complement(5154..5891)
                     /gene="pyrH"
                     /locus_tag="ACL3S0_002025"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGR1312872.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(5975..7309)
                     /gene="trmFO"
                     /locus_tag="ACL3S0_002026"
     CDS             complement(5975..7309)
                     /gene="trmFO"
                     /locus_tag="ACL3S0_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGR1312873.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGAGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(7554..7721)
                     /locus_tag="ACL3S0_002027"
     CDS             complement(7554..7721)
                     /locus_tag="ACL3S0_002027"
                     /inference="COORDINATES: protein motif:HMM:NF036719.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR1312874.1"
                     /translation="MSVVLFFQVKIKYHEDSQFKGDHYVECYAVLDNTVIARDRITVP
                     IDPLCGKDFIE"
BASE COUNT         2171 a         1795 c         1518 g         2287 t
ORIGIN      
        1 taaaaataac gaaaaccgtg tcgccctcac acctgcaggt gttcatagct tagttagtcg
       61 tggtcatcgt gtccttatcg aaacaaatgc tggtctcggt tctggcttta ctgatgctga
      121 ctatcaaaag caaggagctg agattgtcgc tactgctggt gaagcttggg cagcagagtt
      181 ggttgtgaaa gtaaaagaac ctttaagttc tgaatacggt tacttgcgcg acgatcttct
      241 tctcttcacc tacttgcaca tggccgctgc tccagaatta gcagatgcta tgttagcagc
      301 aaaaacaaca ggaattgcct atgaaactgt tcgtgacaat caaggacaac taccgctcct
      361 cgttcctatg agtgaggttg caggtcgtat ggctgtttaa atcggagctc acttccttac
      421 taagcaagct ggtggctctg gtgttctact tggtggtgta ccaggtgttc caaaaggaaa
      481 agtaactatc atcggtgatg gtgtcgtcgg tacacatgct gcccgcatcg cccttggtct
      541 tggtgctcaa gtgactattt tagatattag tgccaagcgt ctctcagttc tagaagaagt
      601 ctttggaagt caaattcaaa ctcttatgtc taattcattc aacattgaag caagtgtgag
      661 agatgctgat gtggtgattg gagccattct catccctggt gcaaaagcac cggaattggt
      721 gacagatgag atggtcaaac aaatgcgtcc aggctctgta tcgttgacat tgctgttgac
      781 caaggtggcc ttatcgaaac agctgaccgt gtgacaacgc acgatgaacc cgtctatgaa
      841 aaacacggtg ttctccacta tgccgttgcc aatatccctg gtgcggttgc ccgcacttca
      901 accatcgccc taaccaatgt cactcttcct tatatcgaag ctttggctgg caaaggattc
      961 gcacaagcaa tctctgaaga tgaaggcttg cgtcaaggtg tgaccactta tcaaggttac
     1021 ttgactagcc taccagttgc tcaaggactt aatcgtgact acactgatat caatgattta
     1081 gtataaattt tgaaaagaaa agggtgactt cgcaagtcct acccactgtg ctttgtgtca
     1141 tcagctatta catcgttggt ttattgtact gtatactttg caactggaga ctttcgttcc
     1201 agactcaatt gtgcataaga aactctaaat tgaataaagt caacagagtt tcgcccaacc
     1261 acttcgtctt gtaatgacaa ttatataaac caaaggaagc tgagctcttt agtcccagct
     1321 tctttttata tataaaattt tacccgtgca aagacagggc cttagcagac ttctttttta
     1381 cttcgttcac ccttgctttt tctttttagg tttgggcgtt ggcagttggt tatacatagc
     1441 taaaatcagg tcttatagaa acatcttatt atcaagttct tccactcaaa tcatttcttt
     1501 ggcacctttg tatggaaact caaaagaaga ttggtcaatc ttatctaaga ctgcttgcac
     1561 gggtttaact aaaaagcgat cgtcataaat gccgccaata atcttgccgc ggaagtaaag
     1621 aatatactcc ccaatcatgg aacggtaagt cacatcatct aatcctgata attgttccaa
     1681 aacaaattcc aaatagttct tacttgatgc catttctaat cttctaggct ctgttcagcg
     1741 ataacaaccg catagagttc ttgcttaacc tcgcatccaa ttgatttaaa gccctgcttt
     1801 tcccaaaaat gctgagattg cggatttccc ttaacataag ccaaacgtgc ctttcgaaag
     1861 ttcttagcaa aataagctag tgcttctgtc acaatatgac taccaatccc tttcctctga
     1921 taggcttgat caaccataaa caaaccaata aaaacagtct cctcatcagg atatgcatag
     1981 acaaaatcca taacagccac aaggtcagat ccattccaaa atccaacaaa aaacttatca
     2041 gccttagctt taccttcagg tagacaaagc atgtcctctt ttacagttgc aaaatttggc
     2101 tctggtggac aatgctgaaa atacagagga ttactttcat ataaagataa aatacttgga
     2161 atatcctttt cagttagtat cctacaactg taatacttag atagttggtc aatcatcttt
     2221 tcaaattcct actttcttgt gccctgtgat tatgacacag gaagatgcac tgatcgtcat
     2281 cagccacata aaagttcttt ccatcgtgcc taatcgttgt ctcaaacctt tagcctatac
     2341 aactggattt tcctctctca aaagtatatt cttttgcagg cgaacttcct caaaatcagt
     2401 cgtgtgcaac ttcagtagaa tattcatagg ctcggataat ctgagcgaca actggatggc
     2461 gaaccacatc cttggctgaa aaatgaacaa agtcaatctg atggatgttc ttgagtttct
     2521 cttgagcatc aatcaaaccg gacttgacat tacgtggcag gtcaatctga ctgatatctc
     2581 cattgacaat catcttagaa tgaaagccta aacgcgtcaa gaacatcttc atctgcatga
     2641 tggtcgtgtt ttgcgcctca tcgagaatga caaaggcatc atccaaggtc cggccacgca
     2701 tataggcaag gggcgcaatt tcgataattt cacgctccat gagacgagtc gtttggtctt
     2761 tcccaagaat ttgatacaag gcatcgtaaa caggacgaag gtaaggatcc accttctcct
     2821 taagatcacc cggaagaaat ccaagactct ctcccgcttc caccgctgga cgagttagga
     2881 taattcgctt gacttgccca cgtttaaggg cagtcactgc caaggtcact gcaaggaagg
     2941 tcttccctgt acctgcaggc ccaattccaa aggtcacatc atgctgtttg acactgtcca
     3001 cataaagttt ttgacctaag gttttgacgc ggataggctt cccagtatta tccttgatga
     3061 tttcttcttc gtaaagggcg acaaacttat caatttcatc gtttttgacc atgctaattg
     3121 cagtcaccac atctggcgta ccaacggtca tcccacgatt taccaagacc atcaaagcct
     3181 gaataacttg acgggcttcc tcacaggcag actcttctcc caaaacctgg acaatctccg
     3241 tacgagcatg aatcacaaca tcaagctctt cttccatcaa acgaagatgg cgttcattgg
     3301 aaccaaaaag atgaaacagg tcatctggat gactcagttg aatgtctatt gaatgttcct
     3361 tcaaataaag aacctctcta atccttttat ttctttttat tatagcagag ggatggagaa
     3421 attactagcc caaacctagt gaataaatgc tagtgttcta agtattcttg ccagatagcg
     3481 tcaaagtctc ctaggttaaa agagaaactg gcatgctcct ccaaaaagcg actgacctca
     3541 tcaaaatcat ctgtgtgttt tggaaaagct gcctcttcaa aagcgaggtc tgccaaaatt
     3601 gctttgggac tgttactttt aggattgcgc tcggtcatga gccaagtgta aaatgatttt
     3661 ctcataagcc tccctaaatc aactctgtcc caaactggtc ctgcttgatt ttaccagcct
     3721 tcataagacc acctaaagct ttcttgaact gacctttaga aatgccaaag gttgccttga
     3781 tgtcgtctgg agatgactta tcatttaagg tcatgaaacc gccattactt tccaaataag
     3841 tcaaaatcat ctgagcatcg ttttccaaca tttcaaagga gcgtggtttg agggagaggt
     3901 tcagagtgcg gtccacttca cggaaaccaa taacgcgcgc atctaatact tgccccaaac
     3961 gtggctctgc gtaacgctcg ctaggatgaa taaaaccaag catattattt tctggtaggt
     4021 aaacaaaagt tcctgacagc ttgagacggt aaacaatggc tggccagttt tggttctgca
     4081 tgttgttgta ggcaggacga gcaagacgtt ggaagtcttc ttgataagcc aagaggcccc
     4141 agatacggtc tttcttatcc acttcaagac ggatgtagag ttggtcgccc ttcttaggcc
     4201 agagttcctt gagctcaggg agaatatcga gtgacacaac gatttccttg tcaggaaggc
     4261 ctgtatccac aaagacaccc aagtccttac gaacctctgt gacacgtccc caaccaaatt
     4321 ggtcctgagt ggcagtcact tctaaggttg tcaggcggag tttttgcttc atatccgtgt
     4381 atgcaaaacc tttgaccgta tcccctactg tatgttggcc ttcttcctta gcaagagcat
     4441 aggtttgacc atccttttgc acaaagtaaa aacggtcgtt ttcatcgatg atcagtccaa
     4501 cgataaaact tgcaagattt gtattcatat ttccttcttt cgaataaaac tcagccagca
     4561 atgccaactg agtttttctg tttattttta gacttccaaa agttctttct ctttgttagc
     4621 agtcatgtcg tcgatgtgtt taacagcatc gtctgttact ttttgaatgt ctttttcaag
     4681 agtcttcaat tcgtcttcag tgatttcttt tgctttttct cgtttcttag cttcgtccat
     4741 agcatcgcga cggatattgc ggacagccac tttagcattt tcgccgacct tcttcacttc
     4801 tttagcaagg tcacgacgag tttcttctgt aagagctggg ataaccaagc gaatcacaga
     4861 accgtcatta gccggtgtga taccaagatc agaagcgttc aaggcacgtt cgatgtcttt
     4921 caatgaagac ttgtcaaatg gtgttaccaa caaaacacgc gcttctggaa tcgtaattga
     4981 agcgatttgg ttaagaggag tttcgactcc atagtattct acatgtacac ggtcaagcaa
     5041 gcttgcattg gcacgaccag cacggatacc accaaattca cgagcaagtg attggtgaga
     5101 ctgggtcatt ctctctttag ctttttcaat aattgcgtta gccatattct ttcttattcc
     5161 ttttcttcga tattatttga aactgttgtt ccgatatttt caccaaatac gacacgtttg
     5221 atgtttcctg gttggttcat gttgaagaca accaagtcaa tgtcgttgtc cattgagagg
     5281 gttgaggctg ttgagtccat gatacgaaga cctttgttga taacatcacg gtgggtcaat
     5341 tcttcaaact taacggctgt cttgtccttc ttaggatcgg cattgtacac accatcgacg
     5401 ccatttttag ccatgaggat ggcatctgct tcgatttcag ctgcgcgaag agccgctgtt
     5461 gtatctgtcg agaagtatgg tgaaccaatt ccagcaccaa agataacgat acggcctttt
     5521 tcaaggtgac gaagggcacg tccacggaca taaggctctg ccacttgttg catggcaata
     5581 gctgtttgta cacgcgtatc aaccccaact tgttgcaatg aatctgccat cacaagagca
     5641 ttcataacag tcccaagcat tccagtgtaa tctgcctgaa cacggtccat acctgcttct
     5701 gctgcaggtt ctccacgcca gagatttcct ccaccaataa caagggcaat ttcgatacct
     5761 aagctatgaa cttcttgaat ctcttttgcg attgtttgaa ctgtttggat atcaatccct
     5821 acgccacgtt caccggcaag ggcttcacct gataacttga ttaaaatacg tttatacttg
     5881 ggattcgcca ttttcactct ccttctttca tcctacctat tttatcacaa tttctaagat
     5941 ttttatagta tcatgagcaa ttctttcaaa aaaattagac agtcaaaaat tcctctaagt
     6001 cggcaagggc acgctctgca attttttcat aacgagcctt cttatcacgg atacgctcgc
     6061 cttccaactc cttgatgatc ccaaaattga cattcattgg ttggaaatgt ttgctgtcgg
     6121 catgggtaat gtaatgagct aagcttccaa tcgctgtcgt ctcggggaaa ataacctcgc
     6181 tttcttcctt gaagagacga gctgcgttaa ttcccgcaac taagcccgaa gccgccgact
     6241 caacatagcc ttccaccccc gtcatctgac cagcaaagaa gagatttggt tgtttcttag
     6301 aacggtaagt ctgctcaaga agatttggtg aatccatgta agaattgcga tgcatcacac
     6361 cataacggac aaactccgca ttttcaagac ccggaatcat ttggaagaca cgcttttgtt
     6421 ctccccattt gaggtgggtc tggaaaccaa caatattgta gaggctacca gctgcattat
     6481 cctgacgaag ttgcacaacc gcataaggtg ttttaaattc tccatcacga ggtcctgtat
     6541 agtcgtctgg gtactcaaga ccgactggct tcatagggcc ataaagcata gttttaatgc
     6601 cacgtttggc catgacttcg ataggcatac atccttcaaa gtacttttct ttttcaaaag
     6661 aattaagcgg tgcttcttct gcattgacca aagcttcatg gaaatccata aattcttgct
     6721 tggtcatagg ggcattgagg taggccgctt ctcccttatc ataacgtgat ttgaggtaga
     6781 ccttgctcat atcgatagtg ttgacatcga taataggcgc tgccgcatcg tagaaataaa
     6841 aaccagcacc gtcattaaga gcatgaatct tttcagctaa ggcatcactt gtcaaaggac
     6901 cagtagcgat aaccgtaata acatctgtcg gcaattctgt aatttcatca cgaaccactt
     6961 caatcaaggg gtggttggca actttttcgg tcaccatttg agagaaacca tcacggtcca
     7021 ctgcaagggc accacctgca ggaacacgtg tagcctcagc agattccaag ataacagaac
     7081 ccaagcgacg catttcttcc ttgagaagac caactgcatt tgtcaaagca tccccacgca
     7141 aagaattgga acaaaccaac tcagcaaaat tgtctgtttt atgctggggt gtagacttga
     7201 caccacgcat ttcatatagt ttaactggaa taccacgctc tgcgatttgg taagctgctt
     7261 cagaacctgc caaaccagca ccgataacat tgatataaga ttgagacacg acactaatac
     7321 ctctttggga gtgtgaagtt aagattcaca ttgaaaaagc caatcagact tacgagcttt
     7381 cgagtttctt ggctcaggct gaaaaagtcc acaggacttt ttcactccca caaatctttc
     7441 tattttttct tctactagta taacaaaaaa agggaagaag gcaaacttcc ctgtttagtc
     7501 attttcttga tgtaaagaga tagtgagtat tccagttaag aatcaattat atgctactct
     7561 ataaaatctt ttccacataa cggatcgata gggactgtta ttctatctct tgctataacc
     7621 gtattatcta aaacagcata acattcaaca tagtgatctc ctttaaactg tgaatcttcg
     7681 tgatatttta tttttacctg aaaaaatagc accacgctca caatttcttc taatagcctc
     7741 agcttcaata tttcttactt tccaatagac t
//
LOCUS       DBEJZV010000062         7596 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.62, whole genome shotgun sequence.
ACCESSION   DBEJZV010000062 DBEJZV010000000
VERSION     DBEJZV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7596
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.62"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..565
                     /locus_tag="ACL3S0_002028"
                     /pseudo
     CDS             1..565
                     /locus_tag="ACL3S0_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            626..1588
                     /locus_tag="ACL3S0_002029"
     CDS             626..1588
                     /locus_tag="ACL3S0_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR1312875.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFMKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1765..2772
                     /gene="gap"
                     /locus_tag="ACL3S0_002030"
     CDS             1765..2772
                     /gene="gap"
                     /locus_tag="ACL3S0_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGR1312876.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHNVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2839..3714)
                     /locus_tag="ACL3S0_002031"
     CDS             complement(2839..3714)
                     /locus_tag="ACL3S0_002031"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR1312877.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVHWKEIVNPGDVCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLA
                     RCKLKTGRTHQIRVHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTF
                     TTLSNTFEKELKKNG"
     gene            3801..5996
                     /gene="pbp2a"
                     /locus_tag="ACL3S0_002032"
     CDS             3801..5996
                     /gene="pbp2a"
                     /locus_tag="ACL3S0_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGR1312878.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEASWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            6049..6201
                     /gene="rpmG"
                     /locus_tag="ACL3S0_002033"
     CDS             6049..6201
                     /gene="rpmG"
                     /locus_tag="ACL3S0_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR1312879.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6211..6387
                     /gene="secE"
                     /locus_tag="ACL3S0_002034"
     CDS             6211..6387
                     /gene="secE"
                     /locus_tag="ACL3S0_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGR1312880.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6442..6978
                     /gene="nusG"
                     /locus_tag="ACL3S0_002035"
     CDS             6442..6978
                     /gene="nusG"
                     /locus_tag="ACL3S0_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGR1312881.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            7101..7580
                     /locus_tag="ACL3S0_002036"
     CDS             7101..7580
                     /locus_tag="ACL3S0_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGR1312882.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT         2406 a         1305 c         1647 g         2238 t
ORIGIN      
        1 gttcaaagct atgggctaca ctcgaaaaaa agaaccacac ctactatgaa caagacccag
       61 aaaagtagcc ttatttctta agaattttaa tagtttaaag cacctagcac ctgtttagat
      121 tgatgaaaca ggattcgata cttattttta tcgagaatat ggtcgctcat taaaaggtca
      181 gttaagaaga ggcaaagtat ctggaagaag atatcagagg atttctttgg ttgcaggtct
      241 aacaaatggt gaattaatcg ctccaatgac ttacgaagag atgatgacga gcgacttttt
      301 tgaagtatgg tttcagaagt ttctcttacc aacattaacc acaccatcgg ttattattat
      361 ggataatgca agattccata gaatgggtaa gctagaactc ttgtgtgaag agtttgggca
      421 taaactttta cctcttcctc cctactcacc tgagtacaat cctattgaga aaacatgggc
      481 tcatatcaaa aagcacctca aaaaggtatt accaagttgc aatacctttt atgaggctct
      541 tttgtcctgc tcttgtttca attgactata gttcacggat acagttggga aagaagctat
      601 taaatatttg gagagtcctt ttgggatgaa catgtcaaat attactatag atgggcaaga
      661 aatggatctg agtcaaacga tgccttctta tgctcaagta gtgagtcttt atgatgatac
      721 aagtatctct gttagtaata atgagacgga caaagtgttg gctggatccc tctatactga
      781 tacaaatgaa cagggattaa cgattccaag cagtttacta aaaaattgga atgaacagac
      841 aggaaaaaat ttgacagcta atgatcttat tggcaaatca gtctcagcca gcattgtaga
      901 aagtgctgcc gaagctagta agattgctca atttcaaacg aagattgtac gtgtaatcaa
      961 tgatgaagat gacatggagg acagcaacag tttcatgctg tctcatcaaa tggaaacgat
     1021 tttgaaagag gctggattta tgaaagctgt atcttatttt atcttggaac tcaaagatcc
     1081 atcacagaca aaagtagtaa cagaagaatt acagaaaaat aagaagtata ctgtgctttc
     1141 tcaacagaga gttcttgata ttgtgattac ctttattcgt gttattcagg gattattgat
     1201 tgtgctttca tcacaagcta ttgtggtagc agcggttatg attggtatta ttatttacat
     1261 caatatcatg caacgttcca aggaaatagg tgtcatgaaa gcagttggtt atcagaatcg
     1321 tgatgtcaaa ggaattttta tttacgaggc tatctggatt gtaggcatcg ccttgttgct
     1381 ggcatttttg gttgcacaag gggtgggaag tttggcgaat gcgattgtaa gtcactttta
     1441 cccatccatc actaaggttt ttgaattaaa tcttttatct gttttaggaa ctctagtttt
     1501 cgctctatta cttggttatg tctcagccta cttcccggcg cgtaagatta gtaaaatgga
     1561 tcctgtagaa ccgttacgct atgaatagta agggattcct tgatttacag tcttaaaaag
     1621 aaactaacat agaaaaacaa tggccatact tgcaattcaa ctcaaatagt tgtataatag
     1681 gtttgttgaa aggtgatttg tagtgattca agttactctt ttcacaataa aaatttcatg
     1741 attttcataa ggaggaaatc actaatggta gttaaagttg gtattaacgg tttcggacgt
     1801 atcggtcgtc ttgctttccg tcgtatccaa aacgtagaag gtgttgaagt tacacgcatc
     1861 aacgacctta cagatccagt tatgcttgca cacttgttga aatacgacac aactcaaggt
     1921 cgtttcgacg gtactgttga agttaaagaa ggtggatttg aagttaacgg taaattcatc
     1981 aaagtttctg ctgaacgtga tccagaacaa atcgactggg ctactgacgg tgtagaaatc
     2041 gttcttgaag ctactggttt ctttgctaag aaagaagcag ctgaaaaaca ccttaaaggt
     2101 ggagctaaaa aagttgttat cactgctcct ggtggaaacg acgttaaaac agttgtattc
     2161 aacactaacc acaacgttct tgacggtact gaaacagtta tctcaggtgc ttcatgtact
     2221 acaaactgct tggctccaat ggctaaagct cttcaagaca actttggtgt tgttgaagga
     2281 ttgatgacta ctatccacgc ttacactggt gaccaaatga tccttgacgg accacaccgt
     2341 ggtggtgacc ttcgccgtgc tcgcgctggt gctgcaaaca tcgttcctaa ctcaactggt
     2401 gctgcaaaag ctatcggtct tgtaattcca gaattgaatg gtaaacttga cggatctgca
     2461 caacgcgttc caactccaac tggatcagtt actgaattgg tagcagttct tgaaaagaac
     2521 gttactgttg atgaagtgaa cgcagctatg aaagcagctt caaacgaatc atacggttac
     2581 acagaagatc caatcgtatc ttcagatatc gtaggtatgt cttacggttc attgtttgac
     2641 gcaactcaaa ctaaagttct tgacgttgac ggtaaacaat tggttaaagt tgtatcatgg
     2701 tacgacaacg aaatgtcata cactgcacaa cttgttcgta ctcttgaata cttcgcaaaa
     2761 attgctaaat aattcttgag ttgatagaaa gcaaggcttt gtggtcttgc tttttatatg
     2821 gaaaaatgga tgacacgatc atccattctt ttttaattct ttttcaaatg tatttgaaag
     2881 ggtagtgaaa gttagcttct ctaaagtaag tgggtgggta aaggaaagtc ggaaggcatg
     2941 aagcataagc cgacttgtct ttgatttact attatagaga gggtcgccca ggataggaag
     3001 attatgatgc gaaaggtgca cacgaatctg atgggttcgc cctgtcttta gcttgcaacg
     3061 agccaaggaa gtcttgtttg agaattgctt taatctgctt acatacgttt cagcatattg
     3121 cccatttttt gcatcaacta ttctttttct acgatcatgg cgatcacgtc caattttgtc
     3181 tctgaaaaca agttcttttc tgttgatatt tccatcaact agagcccaat attctctaga
     3241 aatctctttt ttctccaata agcgattgag aatgggcagg ataaaaggat ttttggcaaa
     3301 gagaactaag ccactggttt ccatgtccag acgatgaacg acatagcagg tttggccaac
     3361 ataggtactg acatggttaa gaagggcaat ttcgtttggt tgattaccat gcgttttcat
     3421 cccctctggt ttgtttacaa taatcaagtg ttgatcttga taaacttcct gcactaagtc
     3481 tgggttgccc caagggatcg tcttttggga ataatcttcc tcgtcaaaag tcaactggca
     3541 aacatctcca ggatttacga tttccttcca gtggacttct tcttgattta tcaaaatatg
     3601 tttcttgatt ctcaaaaaat gacggatttt tctagggatg aggagttgtt cctcaagtaa
     3661 ttgctttact gtcatttgag gtagagaggc gggtaatgta aatgtgaatt gcatacagat
     3721 attgtaacaa aaaaagccct atttggatag gaaatagcta aattcttgtc ttcctatgat
     3781 gaagatgata aaataaacgc atgaaattag ataaattatt tgagaaattt ctttctcttt
     3841 ttaaaaaaga aacaagtgaa ctagaggact ctgattctac tatcttacgt cgctctcgta
     3901 gtgatcgaaa aaaattagcc caagtaggtc cgattcgaaa attctggcgt cgttatcatc
     3961 taacaaagat tatccttata ctaggtttga gtgcaggctt gctagttgga atctatttgt
     4021 ttgctgtagc caagtcgacc aatgtcaatg atttgcaaaa tgccttgaaa actcggactc
     4081 ttatttttga ccgtgaagaa aaagaggctg gtgccttgtc tggtcaaaag ggaacctatg
     4141 ttgagctgac tgacatcagt aaaaacttgc agaatgctgt tattgcgaca gaagaccgtt
     4201 ctttctataa aaatgacggg attaactatg gccgtttttt cttggctatt gtcactgctg
     4261 gacgttcagg tggtggctct accattaccc aacagctggc taaaaacgcc tatttatcgc
     4321 aggatcaaac tgttgagaga aaagcgaaag aatttttcct tgccttagaa ttaagcaaaa
     4381 aatatagtaa ggagcaaatt ctaaccatgt accttaacaa cgcttatttt ggaaatggtg
     4441 tgtggggtgt agaagatgcg agtaagaaat actttggagt ttctgcatca gaagtgagtc
     4501 tggatcaagc tgcgactctg gcagggatgc tcaaggggcc ggaactgtat aatcccttga
     4561 attccgtaga agattctact aatcggcgcg atactgtctt gcagaatatg gttgcagcag
     4621 gatatattga taaaaaccaa gaaaccgaag ctgctgaagt tgatatgact tcgcaattgc
     4681 acgataagta tgaaggaaaa atctcagatt accgttaccc ctcttatttt gatgcggtgg
     4741 ttaatgaagc tgtttccaag tataatctaa cagaggaaga gattgtcaat aatggctacc
     4801 gcatttacac agagctggac caaaactacc aagcaaatat gcagattgtt tatgaaaaca
     4861 catcgctatt tccgagggca gaggatggaa cgtttgctca atcaggaagt gtagccctcg
     4921 aaccgaaaac agggggagtt cgtggagttg tcggtcaagt tgctgacaat gataaaactg
     4981 gattccggaa tttcaactat gcaacccaat caaagcgtag tcctggttct acaattaagc
     5041 ctttagttgt ttatacgcca gcagttgaag caagctgggc tttgaataag cagttggata
     5101 accataccat gcagtatgac agctataagg ttgataacta tgcagggatc aaaacgagtc
     5161 gagaagttcc tatgtatcaa gccttggcag aatcgcttaa tctacctgct gttgccactg
     5221 ttaatgattt gggtgtcgac aaggcttttg aggcaggcga aaaattcgga ctcaacatgg
     5281 aaaaggtcga ccgtgttctt ggtgtcgcct tgggaagcgg tgttgaaacc aaccctcttc
     5341 aaatggctca agcatacgct gcctttgcaa atgaaggttt aatgcctgaa gctcatttta
     5401 ttagtagaat tgaaaatgct agtggacaag ttattgcgag tcataaaaat tcacaaaaac
     5461 gggtgattga taagtctgta gctgacaaga tgaccagtat gatgttgggg actttcacca
     5521 acggtaccgg tattagttca tcgcctgcag actatgtcat ggcagggaaa actggaacaa
     5581 ctgaagcagt tttcaatccg gagtacacaa gtgaccagtg ggtaattggt tatactccgg
     5641 atgtagtgat tagccactgg cttggctttc cgaccactga tgaaaatcac tatctagctg
     5701 gctctacttc aaacggtgca gctcatgtct ttagaaacat tgccaatacc attttacctt
     5761 atacgccagg aagtaccttt acggttgaaa atgcttataa gcaaaatgga attgcaccag
     5821 ccaatacaaa aagacaagta caaaccaatg ataatagcca gacagatgat aatttgtctg
     5881 atattcgagg gcgtgcgcaa agtctagtag atgaggctag ccgggctatc tcagatgcga
     5941 agattaagga aaaggctcaa acaatatggg attcgatagt caatctattt cgctaagatg
     6001 cttgtcaaag cctagctttc ttgttataat ggataagatg gaggcgttat ggcactaaaa
     6061 aaagcaagcc tagcttgtgc ggtttgtggt tcgagaaact attcaatcaa gatcagcgga
     6121 aaccccaagc ctacacgact agaagtaaat aaattttgta agcattgtgg caagtacact
     6181 acacacagag aaacgagata ggagagagcg atgcgtttta ttggagatat ttttagactt
     6241 cttaaagaca caacatggcc aactcgcaag gaaagctgga gagattttcg ttctatcatg
     6301 gaatacacag ctttctttgt agtaattatt tacatttttg accagttgat tgtttcaggt
     6361 ttgattcgat ttattaacat tttttagaag attagtggag ttaattacac tagaaatctt
     6421 ctatttatga aaggaaatat catggatagt tttgataaag gatggtttgt tttacaaact
     6481 tattctggtt atgaaaataa ggtgaaagaa aatctattac aacgtgcaca aacctacaat
     6541 atgttggata atattctacg cgttgaaatt ccaacacaaa cagtgcaagt tgaaaaaaat
     6601 ggaaagagaa aagaagtaga agaaaatcgc tttccaggtt atgttcttgt agaaatggtc
     6661 atgacagatg aagcttggtt tgttgttcga aacacaccaa atgttacagg atttgtcgga
     6721 tcacacggga acagatcaaa accaactcca ttattggaac aagaaattcg tgacattttg
     6781 gtatctatgg gacaaactgt tcaagaattt gatttcgatg ttgagattgg tcaaactgta
     6841 cgtattattg atggtgcttt tgcagactac actggtaaga ttacagaaat tgataataac
     6901 aaagtgaaaa tgattatctc tatgtttggt aatgacacag ttgcagaagt aaacctaaac
     6961 caaatcgcag aattataacc ctgagagagg ctggagcctc tctttttttg tgcagtttag
     7021 gagctaaagg gaacagaatg gagaaaatgg aacaaatgtg ttttctaatc tgttagactg
     7081 tatctagaaa ggggaaaatt atgattaaag aattgtatga agaagtccaa gggactgtgt
     7141 ataagtgtag aaatgaatat taccttcatt tatgggaatt gtcggattgg gagcaagaag
     7201 gcatgctctg cttacatgaa ttgattagta gagaagaagg actggtagac gatattccac
     7261 gtttaaggaa atatttcaaa accaagtttc gaaatcgaat tttagactat atccgtaagc
     7321 aggaaagtca gaagcgtaga tacgataaag aaccctatga agaagtgggt gagatcagtc
     7381 atcgtataag tgaggggggt ctctggctag atgattatta tctctttcat gaaacactaa
     7441 gagattatag aaacaaacaa agtaaagaga aacaagaaga actagaacgc gtcttaagca
     7501 atgaacgatt tcgagggcgt caaagagtat taagagactt acgcattgtg tttaaggagt
     7561 ttactatccg tacccactag taagtcatgc aaaaaa
//
LOCUS       DBEJZV010000063         7237 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.63, whole genome shotgun sequence.
ACCESSION   DBEJZV010000063 DBEJZV010000000
VERSION     DBEJZV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.63"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(32..262)
                     /locus_tag="ACL3S0_002037"
     CDS             complement(32..262)
                     /locus_tag="ACL3S0_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312883.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(280..921)
                     /locus_tag="ACL3S0_002038"
     CDS             complement(280..921)
                     /locus_tag="ACL3S0_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR1312884.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(933..1667)
                     /locus_tag="ACL3S0_002039"
     CDS             complement(933..1667)
                     /locus_tag="ACL3S0_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGR1312885.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1670..1867)
                     /locus_tag="ACL3S0_002040"
     CDS             complement(1670..1867)
                     /locus_tag="ACL3S0_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312886.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(1867..2073)
                     /locus_tag="ACL3S0_002041"
     CDS             complement(1867..2073)
                     /locus_tag="ACL3S0_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1312887.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2083..2397)
                     /locus_tag="ACL3S0_002042"
     CDS             complement(2083..2397)
                     /locus_tag="ACL3S0_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312888.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2551..2679)
                     /locus_tag="ACL3S0_002043"
     CDS             complement(2551..2679)
                     /locus_tag="ACL3S0_002043"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312889.1"
                     /translation="MDRTDEVSSKHGFEVVDETDEVSNHTYGKVKLTWFEEILEEY"
     gene            complement(2739..4028)
                     /gene="hisS"
                     /locus_tag="ACL3S0_002044"
     CDS             complement(2739..4028)
                     /gene="hisS"
                     /locus_tag="ACL3S0_002044"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGR1312890.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKEA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFATKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4106..5353)
                     /locus_tag="ACL3S0_002045"
     CDS             complement(4106..5353)
                     /locus_tag="ACL3S0_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGR1312891.1"
                     /translation="MKLLFRNPAYRILILSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(5546..6397)
                     /gene="rgg"
                     /locus_tag="ACL3S0_002046"
     CDS             complement(5546..6397)
                     /gene="rgg"
                     /locus_tag="ACL3S0_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGR1312892.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6521..6862
                     /locus_tag="ACL3S0_002047"
     CDS             6521..6862
                     /locus_tag="ACL3S0_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR1312893.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            6926..>7237
                     /locus_tag="ACL3S0_002048"
     CDS             6926..>7237
                     /locus_tag="ACL3S0_002048"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312894.1"
                     /translation="MKIKGQTRKLAAGCSKHCFEVMDRTDEVSSKHCFEVMDRTDEVS
                     PKHCFEVVDRTDEVSPKHCFEVVDRTDEVSSKHCFEVMDRTDEVSSKHCFEVVDRTDE
                     VS"
BASE COUNT         2348 a         1497 c         1345 g         2047 t
ORIGIN      
        1 acaaaaatcc gatgaacttc accggactct tttattttga atttttgcct gctttacgct
       61 tttcagcgat ttcggctgcc tttcgaggca agacaatttc cgttatgtaa gccgtcccaa
      121 aacgcagtac acctgcaata ggagcaaaga caactgctag atagttatag aagaaatcgc
      181 ctttgaaggc ataagctagc gctccaatga tgaaaaatag aacgactgcc tgaatcactg
      241 ctaataaaat tactcgtttc atgtgacctc ctgactctat tatagcatga gaatcatcaa
      301 aaagccgact aaattattca aagcgtgaag agaaatactg tagaccagac cttttctgct
      361 aacgtaagcc aaacccaaac taaaaccaag gctaaaatag acaaaaaatt gttgcacatc
      421 acctggaaaa tgaatcaagg caaatagaag actagatacc agaagaaaaa tcagggttcg
      481 tttactattg tcctgcttag gaaagagata gcgtgctaac atccctctaa aaacaatctc
      541 ttccgtcaaa ggagcaaaaa taaccacagc aaagaatgag aaaagtggtt gagacaaggt
      601 caagtctgtc gctatttgct gatttactga aggatcatct ggcaagaaga attgaacgac
      661 cagagataag aaccaaacca agacaggaag ccaaataaat cggttaaagc cgctcttctc
      721 aatatgaaca ggagccttct gataccattt gtaaatgccg tacacatata ctccagccaa
      781 ggccacatag agtagagtaa cagcataggg tgaagcgcct aaagcaagcg acgcagtcgc
      841 gagcccctga ataaagccat agataaataa aaaggataga agggctagaa gaatccagcc
      901 aaggttttta agtaatttca tagataactc ctttatttga aataacgttt taccataggt
      961 aactgcatca cattgatata aacatggatg gctcctacaa gcaagaaagc tagtaactga
     1021 atctctcctg tcaagaaaga aatgataata agaaaaatat ataaggctgg taagacatat
     1081 tggtgtaatt ggaataaaat tcgaaaactc tgttccaaat tagcctgacg ctccccttca
     1141 tcataagaat ttatatagtt caagacatcc tttggtgtag cgaaaaattc caaatcaaac
     1201 tgacgaacaa tcgcaatggt tttaaaaaga gatttttgag cgactaagaa taccacaaag
     1261 agtaagaaag aaaggaaaaa tgtttgaggg tttgtatgca atataatcac ctcacttaat
     1321 gaaataaaaa tagccaatgg aatcgctaca cctgtaatat taaaagcaat ggttccaaac
     1381 tcaagattcc gatacatttg cacataatag gtttcattca gatcgtcatc catttcctct
     1441 tgatacaagg aatgaaattt tctgcttttc tttaagaaat tgaaagtcaa aaacatacta
     1501 atgaaaccta tcagtaaaca aatagctgat atccatggca tcaaggcttt tacatctaaa
     1561 ataatttcgt gggattcgac acgtgcctta aacatcccta caaacatgcc caagaacccc
     1621 cccaagacaa tagacatcaa aaataacaat ctacgtttct ttttcatatt cattctcctt
     1681 tttcacttgc tagatttttg gatttctttt caatccattc agttactggg atgagagcaa
     1741 agtagaccca aacaaattgg tcgctttgat agggattaaa ccagcttagg tccatcccaa
     1801 tcagtagaaa tacgctgact aataaagcta tgaccactac ataataaatc actttatact
     1861 tgttcatcac tcgtcctcct ccaaacgaaa taccgattcg actgtttcgt tgaaaatttg
     1921 agatattttc agggcaatga taatggatgg ggtgtactca tcccgttcta gtaggctaat
     1981 ggtctgtctg gaaacccctg ccagtttggc taggtcggtt tgattgagac catcgcgagc
     2041 tcgaagctct tttagacgat tttttagttg cacgttacac acctactctc cgtcaaattc
     2101 aacggtttgg atatcttcaa tacgttgcaa cttgaatttt tcttttcccg tattatcaac
     2161 actacgtagt ttgacccatt cctcatcaac atccacaact tcccagttat ctggcccaat
     2221 atacactccc gttataattg gttcctttcc aatcatttct tgtaataatc tcgacatttc
     2281 tgcgtttcct ttctcttttc gctcaagttt tttgatttta ttctctagtt tcttgatttt
     2341 tttagaatta ttagaataaa agaaaatcat aaatagtata aatcctagta cccacattat
     2401 aactcctttc tgcttcctat ttcttaactt gaattcattg taacatatct ttttcttttt
     2461 tgacaattat agttgtcaaa aagtttatga tttttgtcat tttgcaaaag aaaaaggtca
     2521 ggagtaagtt cctgaccact ttatctatca ttaatactct tctaaaatct cttcaaacca
     2581 cgtcagcttc accttgccgt aggtatggtt actgacttcg tcagtttcat ctacaacctc
     2641 aaaaccatgt tttgagctga cttcgtcagt tctatccata acttcaaaac agtgttttga
     2701 gcaatctgcg gctagcttcc tagtttgctc tttgattttt attgagtata aaatcctagt
     2761 ttttcaaaga tttctgaaaa gttttggctg attgtctcaa gtgacacttg cacttcttct
     2821 cgggtttggt tgttcttgac cgtcacttgt ccgctttcga cttcgctctc tcccagggtg
     2881 atgagggtct tagtcgcaaa gacatcggct gacttgaact gagctttgag cttacggttg
     2941 aggtaatcac gctctgcttt gaaaccttgt tggcgaaggg cttggactag ttctagggct
     3001 ttgatatttg ccccttcgcc caagactgcg atatagacat ctagggcgtt ttcgataggg
     3061 agggtcacac cttgcttttc aagaatgaga agcaggcgct ctacaccaag tccaaaacca
     3121 aatccagcag tttcagggcc tccaaagtaa gcaaccaaac catcgtaacg accacccgca
     3181 cagacggtca ggtcattgcc ctcaatctct gtgataaact cgaaaatggt gtggttgtag
     3241 tagtccagac cacgcaccat attggtatcg atgatgtaat ctactccaag attttccaac
     3301 atctgacgca cagcatcaaa atgagcttgg ctttcttcat caagaaagtc caagatagac
     3361 ggcgcattct ctactgcctc cttgtcttct ttttccttag agtccaagac acgaagagga
     3421 ttttcctcca agcgacgttg gctatcctta gacaaggtct ccttgagcgg tgtcaaatag
     3481 tcaatcaagg cttggcggta ggctgcacgg ctctcaggat ttccaagagt gttgaggtgc
     3541 aatttgacac cttgaatacc gatttccttc aaaaaatggg ctgccataac gattgtttcc
     3601 acatcggtag ctggattgct agagccaaaa cactcaacac caatctggtg gaattggcgc
     3661 aagcgccctg cctgtggacg ctcataacgg aacataggtc ccatatagta gaacttgctt
     3721 ggcttttgca cttctggggc gaagagttta ttttccacat aggaacggac aacgggcgca
     3781 gttccttctg gacggagggt aatatgacgg tcacccttgt cataaaaatc gtacatttcc
     3841 ttggttacga tatccgttgt atctccgaca gagcggctga taacctcgta atgctcaaaa
     3901 ataggcgtgc gcacttctgc atagttatag cgcttgaaaa tctcacgggc aaagccctca
     3961 acgtactgcc acttagcaga ctcagcaggt aaaatatcct gcgttccttt tggtttttgt
     4021 aatttcatag ggaatcctct ttaaacttaa tagtcttatt ttaccataaa tagagggatt
     4081 aaaacagtaa gaaaaaaatt aggatttaga tatcattttt gagattaaga attgttaaaa
     4141 aaatagctag caaggaaaga ccaacaaata gcatccaagt caactgcatg ttccatacgg
     4201 ctactagtga aaaacaagct gttcccacag gtatggataa ggtaaacaat agacctaaaa
     4261 aattactagt acgagctaga acctctggag ctagattttt catgagcatg gcactaatct
     4321 ttggttgaac tttaccagac acatacagag taaagaagag aaatagcaaa ccaagcacga
     4381 cttgattgaa taaattagcc aaaccaacta gactaagtcc tacggtcgcc cacatcatca
     4441 atctaggcaa ggactgcttc ccaaaataag cattgcccgt aaggctactg atgatgattg
     4501 ctactaaaac acagaattga ttgataaata gtgcctctgt ataagaaaaa ttcaagagag
     4561 aatggctcaa aaagaagata ttataaattc cacccaaagc gccacccaag gaattaataa
     4621 gcaagacagc aaagagcata aaaccaaagt ttttctgtcc acttttaaga aaaacgagac
     4681 gtaaatttcg gtaaattgtt aggaactggt ctttgataga aagcttctca ttttttaagt
     4741 tttcaccatc agcagatgac attgacaggc tcaatttgct ttttcctaaa aagaggatag
     4801 tggctgatac taggaaaaag caggcattga ttcccgcaac gagagaaaaa ttgttgaccg
     4861 atagagctaa gagccagact ccgaaagctt gaccaccaat agctgaaata taggtgatga
     4921 actgtgaaaa agaataagcc tccatcaaat catcttcagc tactttttcc ttaataagag
     4981 gcatacgcag gccacctgca aaatcactga tgatatcact aatgacattg atcaaacaca
     5041 ggctagaaaa ggcaaagaga ctagcttgct gaacaactag ggctgctaga aaaaatagaa
     5101 ccgcctgaaa caaaccgcta tagaccatcc atttgacctt gtccctcgtg taatctgccc
     5161 gaatccctac aaaaactgta aagagggtcg gaagaatcat gacaatattc gccatagcaa
     5221 cagcaaaaga tgcttgtgac aaggtcgatg catagacgat aaagaccagg ttgaaaatcg
     5281 aagcaccaaa agcattgaag aagcgtgata aaatcaaaat tctataagct ggatttctaa
     5341 acaatagttt catagataat ctcccttctt gttcgaacct ctatatgaag tatgactata
     5401 gtatagcact tagaaatttg agagggagaa ctcttgaata tatgcaacaa ataaaatgag
     5461 caaaaagaaa cgatagaact tttgtaatga cctgagagag ggcaatagtt ctatcgcttc
     5521 aaattttttc ttggtttgca gatattcaac attcagtcgt atttctatag tattcggcag
     5581 atttattaca gccaagcatc tcaaaaatac ggacagcatc ctccatcttt ttctggcctt
     5641 ccttgactct accttgcttg ctatcaagga gaccttctgc ccacagataa acaattcgga
     5701 aataggtctc attttccttg tagaaatgct cttcgataac acgtttaaaa taataggcat
     5761 tggtaaattc ttcacactca atactagcta aaaagccatt caatagtata gtatgaaaaa
     5821 ggtttcgatt gccagacatt tccattagaa aatcagattt acgtaccatt tctcgtacat
     5881 atctagtaaa aagagaaaca gataaaaatg gagaactgac tgaaaataaa ttgagttcat
     5941 agattcccca gatctcggta gaaaacaaat aatcatgaag gacttttcct tcctctgctg
     6001 ttaactctac cctttcatcc atgctcttca tataagactt gataataatg gcatttagaa
     6061 tatgtttctg tttgttgtga gaatgggcat gcttttgata ctccctgcga tataagtcct
     6121 caagaggtgc tatattcttt ggttccaaga catctgtaat ttcttttctc aactcagaat
     6181 ctgtatcata ctggaaacct ctcgccagaa agaggatctc ctccacactg gcagatatat
     6241 tttccagagc aaatagaaac ttttccaccg aaagctcact ctgacctgtt tcaaaacggg
     6301 acaacataga cggcgaaaat tgtcctccgg ttgcttgtct cagtgagata tttcttgact
     6361 ctcgtaattg tctaaagact tttccaatct gctccataga cttccccttg attccgtatt
     6421 ttcttcattt tatcatattt ttcagaaaat tcatcaaaaa cttgccaaat tgtcagaatt
     6481 atgagaaaat agaggatatt tatcacgtgg agggactgct atgagagacg atatcaaaat
     6541 caatgaccgt gctttggcct tgcaagacca aattatcgaa aaactagaga aagtttttga
     6601 tacagatgtg gaattggatg tttacaatct aggtctgatt tatgaaatca atctggatga
     6661 aacggggctc tgcaagattg tcatgacctt caccgatact gcctgtgatt gcgccgaaag
     6721 cctgcctatt gaaattgtgg caggtctgaa acaaatcgag ggtatcaaag atatcaaggt
     6781 tgaagttacc tggtcgcctg cttggaaaat cacacgaatc agtcgctatg gccgtattgc
     6841 ccttggacta ccacctcgtt aagcaggcca atcactttta aagatgaaaa aagcaagccg
     6901 aaaatggctt gctttttgat actcaatgaa aatcaaaggg caaactagaa aactagccgc
     6961 aggttgctca aaacactgtt ttgaagttat ggatagaact gacgaagtca gctcaaaaca
     7021 ctgttttgag gttatggata gaactgacga agtcagccca aaacactgtt ttgaggttgt
     7081 ggatagaact gacgaagtca gcccaaaaca ctgttttgag gttgtagata gaactgacga
     7141 agtcagctca aaacactgtt ttgaagttat ggatagaact gacgaagtca gctcaaaaca
     7201 ctgttttgag gttgtagata gaactgacga agtcagc
//
LOCUS       DBEJZV010000064         7113 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.64, whole genome shotgun sequence.
ACCESSION   DBEJZV010000064 DBEJZV010000000
VERSION     DBEJZV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7113
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.64"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..900)
                     /gene="phtA"
                     /locus_tag="ACL3S0_002049"
     CDS             complement(<1..900)
                     /gene="phtA"
                     /locus_tag="ACL3S0_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HGR1312895.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QYREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLS"
     gene            complement(1154..2887)
                     /gene="ptsP"
                     /locus_tag="ACL3S0_002050"
     CDS             complement(1154..2887)
                     /gene="ptsP"
                     /locus_tag="ACL3S0_002050"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGR1312896.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(2893..3156)
                     /locus_tag="ACL3S0_002051"
     CDS             complement(2893..3156)
                     /locus_tag="ACL3S0_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGR1312897.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            3507..3725
                     /gene="nrdH"
                     /locus_tag="ACL3S0_002052"
     CDS             3507..3725
                     /gene="nrdH"
                     /locus_tag="ACL3S0_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGR1312898.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            3806..5965
                     /gene="nrdE"
                     /locus_tag="ACL3S0_002053"
     CDS             3806..5965
                     /gene="nrdE"
                     /locus_tag="ACL3S0_002053"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGR1312899.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            6153..>7113
                     /gene="nrdF"
                     /locus_tag="ACL3S0_002054"
     CDS             6153..>7113
                     /gene="nrdF"
                     /locus_tag="ACL3S0_002054"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGR1312900.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNCGLD"
BASE COUNT         2062 a         1522 c         1329 g         2200 t
ORIGIN      
        1 actcaaaggc agtttgtaga gctgtttcaa gagactatca atgtcattac tttgacttgc
       61 ttgactgtta gtgttgctgt tgttgcttgt gttagtattt gtagttcctg gattgcttac
      121 agaaggtacc cagtttgttc ttgaagtgtt atcgctattt tgtcggcgat aggttcttga
      181 atttgacaga tttccccgac cagataggaa ggcttctgca gcagctaact cgctagctga
      241 taactcattc ttaggaatgt aatggtaatg gtcgccgtga ggaacgatat aagcatcacc
      301 agtatcctct atgatatcag aagcattaaa gatataacca tcatctgtag tatagcgtcc
      361 ttgcgaacgt gccaaggcaa cagctccatc gtttcttgga gtccctcctt cacgatactg
      421 actatgttct tgtttttgtc gattgatttc ctcttttgta cggacgttat ccgcgtgggc
      481 agcatcctta aggtaaacat agtattttcc atctaccttg ataacatatc cacccttgac
      541 ctcattaaca atatcctcat cttttagctt atagtttgga tctttcatga gtaattcttc
      601 actgaaaatc gcatcataag gaaccttacc attgtaataa tgatagtggt cgccatgtga
      661 agtgacatag ccttggtctg ttatcttgat gacgatttgc tcagcattga ttccttcacg
      721 cttgctaacc tcatcaggag tcaaattctc cgttttttgc gtcgcttgtt ttccatctat
      781 ataggaaaca cgattatttt ccttaaccgt tctagcttga tacagtccca actcgtaaga
      841 acaaacactt aaaatcaaag ctgccgcaga accaacaagg tatttcttat taattttcat
      901 cgaaactctc tttctatttg atatttctag ttgcaattca tttctaaatt gcagaaactc
      961 ctctctatta cttaactggt taatagttta ctcctaaatc tccaacttgt caagaatttt
     1021 atgaaccatt taagtatttt ttgttctgac cactactttt tcaaggttgg actttctata
     1081 aaaaagattt tcttgaaaat tctttttaaa atatcaaaaa aatccctgta actgagttgc
     1141 agggacttgt cgattaatca aaattaacgt attctttttg aagttcaaga acttcttcca
     1201 ttgttgagca ttctgtaagg gcacggtttg cgtactcttc catcttagct gtgtcgagtt
     1261 tcttcatcaa gctgcgtgta cgaagtacag atgttgctga catagagaac tcatccaagc
     1321 ccattccgac aagaagtgga acagcttgtt ggtcaccagc catctcacca cacataccag
     1381 cccatttacc ttcagcgtga gctgctttga tcacattgtt aatcaagcgt aggattgatg
     1441 ggttgtatgg ttggtaaagg tatgaaactt gttcgttcat acggtctgct gccattgtat
     1501 attggatcaa gtcgtttgta ccaattgaga agaagtcaac ttctttagca aattggtctg
     1561 caagcatagc cgctgcagga atctcaatca tgataccaac ttggatgtta tccgcaactg
     1621 caacaccttc agcaagaagg tttgcttttt cttcatcaaa gactgctttc gctgcacgga
     1681 attctttcaa gagcgcaacc attgggaaca tgatacgcaa ttgaccgtga acagacgcac
     1741 gaagaagagc acggatttgt gtgcggaaca tagcatctcc agtctcagag atagagatac
     1801 gaagagcacg gaatccaagg aatgggttca tttcgtgagg catatcgaag taaggaagtt
     1861 ccttatctcc accgatatcc attgtacgaa cgacaacagg tttaccgttc attccttcaa
     1921 gaacagcctt gtatgcttca tactgctcat cttcagttgg gaagtcttga gaatccatgt
     1981 acaagaactc tgtacggtaa agtccaacag cttctgcacc gttgttgtta acaccttcaa
     2041 cgtcttttgg agtaccaata ttggcagcca actcgaagtg tttaccgtca gcagtcactg
     2101 tttgagcatc tttcaaaagt gcccattcag ctttttgttt cgcataggct tcaccagctg
     2161 ctttaaattc tgccgcttgt tcatctgttg ggttgataat cacttctcca gtgatcccgt
     2221 taacagcaag gatgtcaccg tctttaacga tttcagtgat gttatttgta cctaatacag
     2281 cagcaatttc aagtgtacgt gccatgatag ctgagtggct tgtacgtcca ccaatgttgg
     2341 ttacaaaagc ttttacaaag tttttgtcca attgagctgt atctgaagga gtcaagtcat
     2401 gcgcaatcac aatcacttct tcattgatag aagctgggtt tggcaatttt ttaccaagaa
     2461 ggtttgccaa tacacgtttt gtcacgtcgc ggatatccgc tgcgcgttct tgcatgtatg
     2521 ggttgtcttc catgccttca aagatagtga taaacatatc tgtaacttct ttcagacctg
     2581 cttctgcatt cactttcttc gcacggatag tttccttgat ttggctgatc atttctgggt
     2641 cagcaagaac cattaagtga gcatcaaaaa cttgagctgc ttcttcaccg agcgtaccta
     2701 ctgctttctc gcgaataaca gaaagctcgt cttgtgatgc ctgtagagcg gcatcaaggc
     2761 gagcttcttc tgcgtttgta tcttcgactg taatagtctc aaatgacaaa tccggctgaa
     2821 cgagtagata tgcttttgca actgcaacac cgtcagatgc tgcgattcct ttaagcattt
     2881 ctgtcatttc ccttatgcca atccttcttt ttccattgtt tctgagattg cagcgatagc
     2941 gtcatctgca tctgcacctt cagctgagat agttacgtca gcaccttgac caacaccaag
     3001 actcataaca cccataattg atttaaggtt aactgattta cctttgtact caagagtgat
     3061 atctgaagca aatttgctag cagtttgtac caacaatgtt gctggacgtg cgtgaatacc
     3121 tgtttctgcc actacgtgga aatctttaga agccatagtt tgactctcct tttgttcttt
     3181 ctttttttga gttatatgtg ataaccctta caatttagta ttataccatc ttctaggatt
     3241 tttttcaagc attttctgga ttttccttca atttcctttc agataacttg ctgaaaatct
     3301 tctatcctag ataacaaaac acaggatata gtttcttcaa aaacaattta taggataatc
     3361 attgctattt cacaatacaa acactatata ttgtgtttat atataaaaac aacaaaagaa
     3421 caccactata tttagtttaa atcattgaca aaattttatt ttctgatata ctaagatagt
     3481 attaaatttt gaagaggagt tacacaatgg taaccgttta ttctaaaaac aattgtgtcc
     3541 aatgtaaaat gaccaagcgt ttcttggaca gtaataatgt ctcttatcgt gaaatcaatc
     3601 ttgatgagca acctgagtac gtcgatcaag ttaaagagct cggttttagc gcagctcctg
     3661 ttatccaaac accaactgaa gtcttttcag gtttccaacc aggaaaactg aaacaattag
     3721 cataatctta gtacatcatc cagaagaaac tgcttttagg gctaacttag aagcctttct
     3781 tttgtaatta gataagggaa attttatggg attaaaacat cttgaagacg tgacttactt
     3841 ccgtcttaat aacgaaatta accgtcctgt taatggacaa atcatgcttc ataaagataa
     3901 ggaagccttg gatgctttct ttaaagaaaa tgtagttcca aacactatgg tttttgattc
     3961 aatcaaagac aaaatcaatt acctcattga acacaactac atcgaaacag cctttatcaa
     4021 gaaataccgt ccagagttct tggaagaatt ggctcaattt atcaaagacc aaaacttcca
     4081 attcaagtca ttcatggcag cttataaatt ttacaatcaa tatgccttaa agactaatga
     4141 cggtgaatac tatcttgaaa atatggaaga ccgtgtcttc ttcaacgccc tttatttcgc
     4201 tgatgggaat gaagctgttg caatcgatat tgccaatgaa atcatccacc aacgctacca
     4261 acctgctact ccttccttct tgaatgctgg acgtgctcgt cgtggggagt tggtatcttg
     4321 tttcctaatc caagtgacgg atgatatgaa ctctatcggg cgttctatca actcagctct
     4381 tcaactttca cgtattggtg gtggtgtggg aattaccctc agcaaccttc gtgaagctgg
     4441 tgcacctatc aaaggctatg aaggagctgc ttcaggtgtc gttcctgtta tgaagctttt
     4501 tgaagacagc ttctcttact ccaaccaatt ggggcaacgt caaggtgccg gcgttgtcta
     4561 cctcaacgtc tttcacccag atatcatcgc tttcctttca actaagaaag aaaacgctga
     4621 tgaaaaagta cgtgtcaaga ctctatcact tggtgttgta gtacctgata aattctacga
     4681 attggctcgt aaaaatgaag aaatgtacct cttcagccct tactctgtag aaaaagaata
     4741 cggtgtgcca ttcaattaca tcgacattac tgaaaaatac gatgaattgg tcgcaaatcc
     4801 aaatattcgc aagacaaaaa tcaaggcgcg ggatttggaa actgaaatct ctaaattgca
     4861 acaagagtct ggctatcctt atgtagtcaa catcgatacg gctaaccgtg caaatcctgt
     4921 tgatggaaag attatcatga gtaacttgtg ttctgagatt cttcaagttc aagaaccaag
     4981 cttgatcaac gatgctcaag aattccttca aatgggaaca gatgtttcat gtaacctggg
     5041 ttcaaccaac gtggttaaca tgatgacttc acctgatttt ggtcgttcta tccgtgctat
     5101 ggttcgtgcc cttactttcg ttacagatag ttcacatatc gtagctgtac caacgattga
     5161 ccatggaaat agccaagccc acacctttgg tctcggtgcc atgggactgc acagctacct
     5221 tgcccaacaa ctcattgaat atggttcacc tgagtctgtt gaatttacaa gcatctactt
     5281 tatgcttatg aactactgga ccttggtaga gtcaaacaat attgcacgtg aacgtggtat
     5341 taccttccac aactttgaaa aatcagacta tgctaacgga agttactttg acaagtatgt
     5401 aactggtgaa tttgttccaa catcagaccg tgttaaagaa ctcttcaaaa atgtttttat
     5461 ccctggtgtt gctgattggg ctgaacttcg cgacaaggtt caagaagatg gtctttacca
     5521 ccaaaatcgc cttgctgtag cgccaaatgg ttctatcagc tatatcaacg acgtttctgc
     5581 ttctatccac ccgattacgc aacgtatcga agaacgccaa gagaagaaaa ttggtaaaat
     5641 ctactaccct gctgctggct tgtctacaga aaccattcct tactacactt ctgcctacga
     5701 tatggatatg cgtaaagtca tcgatgttta cgctgctgcg actgaacacg tggatcaagg
     5761 actttcactc accctcttca tgcgcagtga cattccaaaa ggcctttacg aatggaagag
     5821 ggaaaataaa caaacgacac gtgatttgtc catccttcgt aactatgcct ttaacaaggg
     5881 aatcaagtct atctactacg tccgtacctt tacagatgac ggtggagaag tcggcgccaa
     5941 ccaatgtgaa agctgtgtga tttagtttct agcatagaaa cattattttt ccctaagcag
     6001 cactgataaa atcaaatcta ctatgtcata atataattta tgtaacattt taaaagtcgg
     6061 gcttccgact ttttgtgcga tactcctata gaattatggt aaagtagaaa taattgtgag
     6121 ttcgcaatac taaacacaga aagagatttt aaatggaaac ttactacaaa gccattaact
     6181 ggaatgccat cgaagatgtc atcgacaaat caacttggga aaaactgacg gagcaatttt
     6241 ggctcgatac acgtattccc ttatcaaacg acttggatga ctggagaaag ctatctaaca
     6301 aagagaaaga cttggtcgga aaagtttttg gtggtttaac ccttcttgac actatgcaat
     6361 ctgaaactgg ggttcaagcc cttcgcgcag acatccgtac accacatgag gaagctgttt
     6421 tcaataacat ccaatttatg gaatctgtcc acgctaaatc ttactcatca atcttttcta
     6481 ccttgaatac taaggctgag attgaagaaa ttttcgaatg gaccaatacc aatccttacc
     6541 tacaaaagaa ggctgagatt gtcaacgaaa tctacctaaa cggcagccca cttgaaaaga
     6601 aagttgccag cgtcttcctc gaaaccttcc tcttctactc tggtttcttc actcccctct
     6661 actatctcgg taacaacaaa ctagccaacg ttgcagaaat cattaaattg attattcgtg
     6721 acgagtctgt tcacggaacc tacattggtt acaaattcca acttggtttc aatgaattgc
     6781 ctgaagaaga gcaagaaaaa ctcaaagaat ggatgtacga cctactctat actctttatg
     6841 aaaatgaaga aggctacaca gagagtcttt atgacggtgt tggttggact gaagaggtta
     6901 aaaccttcct tcgctacaat gccaataaag ctctcatgaa catgggacaa gatccacttt
     6961 tcccagattc agctgaagat gtcaacccaa tcgttatgaa cggtatttca acaggaactt
     7021 ccaaccatga cttcttctct caagtcggaa atggttacct tcttggcgaa gttgaagcca
     7081 tgcaagatga tgactacaac tgcggtttgg act
//
LOCUS       DBEJZV010000065         7089 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.65, whole genome shotgun sequence.
ACCESSION   DBEJZV010000065 DBEJZV010000000
VERSION     DBEJZV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7089
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.65"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            394..6822
                     /locus_tag="ACL3S0_002055"
     CDS             394..6822
                     /locus_tag="ACL3S0_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR1312901.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANRADENG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTEVENHQGNEEATEEK
                     SSFTIDRNISTIREFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAYE
                     DESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEIK
                     ATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAEIKIRMPEKNKETK
                     AEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYA
                     LKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQA
                     VLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSN
                     VEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWEL
                     RVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGN
                     VYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNN
                     GFDGEIQEQHIYINGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGE
                     VSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDA
                     GYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQR
                     EDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGI
                     FLGLKKKNQD"
BASE COUNT         2791 a          971 c         1360 g         1967 t
ORIGIN      
        1 ccatctacaa cctcaaaaca gtgttttgag ctgactacgt cagttccatc cacaacctca
       61 aaacagtgtt ttgagctgac tacgtcagtt ccatctacaa cctcaaaaca gtgttttgag
      121 caacctgcgg ctagtttcct agtttgctct ttgattttca ttgagtacta atcttacttt
      181 ttaacgtgtg ctaaaaaata aattaatgca tgttaatttt tcttgaatta aattttttta
      241 aatgatatac tgtttttata gagagataac aattatatat aaatgtacta ctctatttcc
      301 tagataatac ttagtaaaac tttttataac aaaggctagc aaagttaaag tttattatct
      361 attggaagtt aaataaatat gtaaggaatt aaaatgaaaa aaagtacagt attgtcatta
      421 accacagctg cagttatttt agcagcctat gcccctaatg aggtagtctt agcagacaca
      481 tctagctctg aagatgcttt aaacatctct gataaagaaa aagtagtatt agataaggaa
      541 acagaaaata aagagaaaca tgaagatatt cataatgcta tagaaacttc acaggatttt
      601 aaagagaaga aaacagcagt cattgaggga aaagaagttg ttagtaaaaa tcctgtgaca
      661 gacaataaca ctagcaatga agaagcaaga atcaaagaag attccaatca atcccaagga
      721 gatcatacgg actcatttgt gaataaaaac acagaaaatc ccaaaaaaga agataaagtt
      781 gtctatattg ctgaatttaa agataaagaa tctggagaaa aagcaatcaa gcaactatcc
      841 aatcttaaga atacaaaagt tttatatact tatgatagaa tttttaacgg tagtgccata
      901 gaaacaactc cagataactt ggacaaaatt aaacaaatag aaggtatttc atcggttgaa
      961 agggcacaaa aagtccaacc catgatgaat catgccagaa aggaaattgg agttgaggaa
     1021 gctattgatt acctaaagtc tatcaatgct ccgtttggga aaaattttga tggtagaggt
     1081 atggtcattt caaatatcga tactggaaca gattatagac ataaggctat gagaatcgat
     1141 gatgatgcca aagcctcaat gagatttaaa aaagaagact taaaaggaac tgataaaaat
     1201 tattggttga gtgataaaat ccctcatgcg ttcaattatt ataatggtgg caaaatcact
     1261 gtagaaaaat atgatgatgg aagggattat tttgacccac atgggatgca tattgcaggg
     1321 attcttgctg gaaatgatac tgaacaagat atcaaaaact ttaacggcat agatggaatt
     1381 gcacctaatg cacaaatttt ctcttacaaa atgtattctg acgcaggatc tgggtttgcg
     1441 ggtgatgaaa caatgtttca tgctattgaa gattctatca aacacaacgt tgatgttgtt
     1501 tcggtatcat ctggttttac aggaacaggt cttgtaggtg agaaatattg gcaagctatt
     1561 cgggcattaa gaaaagcagg cattccaatg gttgtcgcta cgggtaacta tgcgacttct
     1621 gcttcaagtt cttcatggga tttagtagca aataatcatc tgaaaatgac cgacactgga
     1681 aatgtaacac gaactgcagc acatgaagat gcgatagcgg tcgcttctgc taaaaatcaa
     1741 acagttgagt ttgataaagt taacataggt ggagaaagtt ttaaatacag aaatataggg
     1801 gcctttttcg ataagaataa aatcacaaca aatgaagatg gaacaaaagc tcctagtaaa
     1861 ttaaaatttg tatatatagg caaggggcaa gaccaagatt tgataggttt ggatcttagg
     1921 ggcaaaattg cagtaatgga tagaatttat acaaaggatt taaaaaatgc ttttaaaaaa
     1981 gctatggata agggtgcacg cgccattatg gttgtaaata ctgtaaatta ctacaataga
     2041 gataattgga cagagcttcc agctatggga tatgaagcgg atgaaggtac taaaagtcaa
     2101 gtgttttcaa tttcaggaga tgatggtgta aagctatgga acatgattaa tcctgataaa
     2161 aaaactgaag tcaaaagaaa taataaagaa gattttaaag ataaattgga gcaatactat
     2221 ccaattgata tggaaagttt taattccaac aaaccgaatg taggtgacga aaaagagatt
     2281 gactttaagt ttgcacctga cacagacaaa gaactctata aagaagatat catcgttcca
     2341 gcaggatcta catcttgggg gccaagaata gatttacttt taaaacccga tgtttcagca
     2401 cctggtaaaa atattaaatc cacgcttaat gttattaatg gcaaatcaac ttatggctat
     2461 atgtcaggaa ctagtatggc gactccaatc gtggcagctt ctactgtttt gattagaccg
     2521 aaattaaagg aaatgcttga aagacctgta ttgaaaaatc ttaagggaga tgacaaaata
     2581 gatcttacaa gtcttacaaa aattgctcta caaaatactg cgcgacctat gatggatgca
     2641 acttcttgga aagaaaaaag tcaatacttt gcatcaccta gacaacaggg agcaggccta
     2701 attaatgtgg ccaatgcttt gagaaatgaa gttgtagcaa ctttcaaaaa cacggattct
     2761 aaaggtttgg taaactcata tggttccatt tctcttaaag aaataaaagg tgataaaaaa
     2821 tactttacaa tcaagcttca caatacatca aacagacctt tgacttttaa agtttcagca
     2881 tcagcgataa ctacagattc tttaactgac agattaaaac ttgatgaaac atataaagat
     2941 gaaaaatctc cagatggtaa gcaaattgtt ccagaaattc acccagaaaa agtcaaagga
     3001 gcaaatatca catttgagca tgatactttc actataggcg caaattctag ctttgatttg
     3061 aatgcggtta taaatgttgg agaggccaaa aacaaaaata aatttgtaga atcatttatt
     3121 cattttgagt cagtggaaga aatggaagct ctaaactcca acgggaagaa aataaacttc
     3181 caaccttctt tgtcgatgcc tctaatggga tttgctggga attggaacca cgaaccaatc
     3241 cttgataaat gggcttggga agaagggtca agatcaaaaa cactgggagg ttatgatgat
     3301 gatggtaaac cgaaaattcc aggaacctta aataagggaa ttggtggaga acatggtata
     3361 gataaattta atccagcagg agttatacaa aatagaaaag ataaaaatac aacatccctg
     3421 gatcaaaatc cagaattatt tgctttcaat aaccaaggga tcaacgctcc atcatcaagt
     3481 ggttctaaga ttgctaacat ttatccttta gattcaaatg gaaatcctca agatgctcaa
     3541 cttgaaagag gattaacacc ttctccactt gtattaagaa gtgcagaaga aggattgatt
     3601 tcaatagtaa atacaaataa agagggagaa aatcaaagag acttaaaagt catttcgaga
     3661 gaacacttta ttagaggaat tttaaattct aaaagcaatg atgcaaaggg aatcaaatca
     3721 tctaaactaa aagtttgggg tgacttgaag tgggatggac tcatctataa tcctagaggt
     3781 agagaagaaa atgcaccaga aagtaaggat aatcaagatc ctgctactaa gataagaggt
     3841 caatttgaac cgattgcgga aggtcaatat ttctataaat ttaaatatag attaactaaa
     3901 gattacccat ggcaggtttc ctatattcct gtaaaaattg ataacaccgc ccctaagatt
     3961 gtttcggttg atttttcaaa tcctgaaaaa attaagttga ttacaaagga tacttatcat
     4021 aaggtaaaag atcagtataa gaatgaaacg ctatttgcga gagaccaaaa agaacatcct
     4081 gaaaaatttg acgagattgc gaacgaagtt tggtatgctg gcgccgctct tgttaatgaa
     4141 gatggagagg ttgaaaaaaa tcttgaagta acttacgcag gtgagggtca aggaagaaat
     4201 agaaaacttg acaaagacgg aaataccatt tatgaaatta aaggtgcggg agatttaagg
     4261 ggaaaaatca ttgaagtcat tgcattagat ggttctagca atttcacaaa gattcataga
     4321 attaaatttg ctaatcgggc tgatgaaaat gggatgattt cctattatct agtagatcct
     4381 gatcaagatt catcaaaata tcaaaagctt ggcgagattg cagaatctaa atttaaaaat
     4441 ttaggaaatg gaaaagaggg tagtctaaaa aaagatacaa ctgaggtaga aaatcatcaa
     4501 ggaaatgaag aggctaccga agaaaaatct agttttacta ttgatagaaa tatttcaaca
     4561 attagagagt ttgaaaataa agacctaaag aaactcatta aaaagaaata taaggaagaa
     4621 gacgactttg taactggtgg aaaaagaaca gtagaacttg attataaata tgacgataaa
     4681 ggaaatataa ctgcctatga agatgaaagt gctctagaat atgaaactga aaaatttgac
     4741 gaaataaaat caaaaattta tggcgttcta agcccatcta aagatggaca ctttgaaatt
     4801 cttggaaaga taagcaatgt ttctaaaaat gccaaggtat attatggaaa tagctataaa
     4861 tcgatagaaa tcaaagcgac taagtatgac tcacattcaa aaacgatgac atttgattta
     4921 tacgctaata ttaatgatat tgtggatgga ttagcttttg ctggagatat gcgttttttt
     4981 gttaaagatg atgatcgaat aaaagctgaa attaaaatta gaatgcctga aaaaaataag
     5041 gaaactaaag cagaatatcc ctatgtatca agttatggga atgtaatcga attaggagaa
     5101 ggagatcttt caaagaacaa accagacaat ttaactaaaa tggaatctgg taaaatctat
     5161 tctgattcag aaaaacaaca atatctgtta aaggataaca tcattctaag aaaaggctat
     5221 gcactaaaag tgactaccta taatcctgga aaaacggata tgttagaagg aaatggagtc
     5281 tatagcaagg aagatatagc aaaaatacaa aaggccaatc ctaatctaag agtcctttca
     5341 gaaacaacaa tttatgctga tagtagaaat gttgaagatg gaagaagtac ccaagctgta
     5401 ttaatgtcgg ctttggacgg ctttaacatt ataaggtatc aagtgtttac atttaaaatg
     5461 aacgataaag gggaagctat cgataaagac ggaaatcttg tgacagattc ttctaaactt
     5521 gtattatttg gtaaggatga taaagaatac actggagagg ataagtccaa tgtagaagct
     5581 ataaaagaag atggttccat gttatttatt gataccaaac cagtaaacct ttcaatggat
     5641 aagaactact ttaatccatc taaatctaat aaaatttatg tacgaaatcc agaattttat
     5701 ttaagaggta agatttctga taagggtggt tttaactggg aattgagagt taatgaatcg
     5761 gttgtagata attatttaat ctacggagat ttacacattg ataacactag agattttaat
     5821 attaagctga atgttaaaga cggtgacatc atggactggg gaatgaaaga ctataaagca
     5881 aacggatttc cagataaggt aacagatatg gatggaaatg tttatcttca aactggctat
     5941 agtgatttga atgctaaagc agttggagtc cactatcagt ttttatatga taatgttaaa
     6001 cccgaagtaa acattgatcc taagggaaat actagtatcg aatatgctga tggaaaatct
     6061 gtagtcttta acatcaatga taaaagaaat aatggattcg atggtgagat tcaagaacaa
     6121 catatttata taaatggaaa agaatataca tcatttgatg atattaaaca aataacagac
     6181 aagacactaa acattaagat tgttgtaaaa gattttgcaa gaaatacaac cgtaaaagaa
     6241 ttcattttaa ataaagatac gggagaggta agtgaattaa aacctcatag ggtgactgtg
     6301 accattcaaa atggaaaaga aatgagttca acgatagtgt cggaagaaga ttttatttta
     6361 cctgtttata agggtgaatt agaaaaagga taccaatttg atggttggga aatttctggt
     6421 ttcgaaggta aaaaagacgc tggctatgtt attaatctat caaaagatac ctttataaaa
     6481 cctgtattca agaaaataga ggagaaaaag gaggaagaaa ataaacctac ttttgatgta
     6541 tcgaaaaaga aagataaccc acaagtaaac catagtcaat taaatgaaag tcacagaaaa
     6601 gaggatttac aaagagaaga tcattcacaa aaatctgatt caactaagga tgttacagct
     6661 acagttcttg ataaaaacaa tatcagtagt aaatcaacta ctaacaatcc taataagttg
     6721 ccaaaaactg gaacagcaag cggagcccag acactattag ctgccggaat aatgtttata
     6781 gtaggaattt ttcttggatt gaagaaaaaa aatcaagatt aagataaaag ctatagaaaa
     6841 aaatggttta tgtactgaga ttagatagtg aggtgatgac atagttttgt gaaaacagcc
     6901 atttataact caattattta gtttacttca ctattgatac tatttggagt tattaatgaa
     6961 cttagtttag ataactaatg aattgattga aagggttagt attgacaata ttggtcatat
     7021 tgattagaaa ataaagtcta tcaaaattta aaggctaata gaggtgatga gacaatttca
     7081 aggaattaa
//
LOCUS       DBEJZV010000066         6416 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.66, whole genome shotgun sequence.
ACCESSION   DBEJZV010000066 DBEJZV010000000
VERSION     DBEJZV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.66"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(93..389)
                     /locus_tag="ACL3S0_002056"
     CDS             complement(93..389)
                     /locus_tag="ACL3S0_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR1312902.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(379..561)
                     /locus_tag="ACL3S0_002057"
                     /pseudo
     CDS             complement(379..561)
                     /locus_tag="ACL3S0_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
     gene            610..1374
                     /locus_tag="ACL3S0_002058"
     CDS             610..1374
                     /locus_tag="ACL3S0_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGR1312903.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1576..1815
                     /locus_tag="ACL3S0_002059"
     CDS             1576..1815
                     /locus_tag="ACL3S0_002059"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312904.1"
                     /translation="MILFENLFKPGQLHLAVDMLLTSSVLSATSKQCFELTSSVLSTT
                     SKQCFEQPVTSFLIDALIFIAYNQKEKFSPEKHIE"
     gene            1984..3363
                     /locus_tag="ACL3S0_002060"
     CDS             1984..3363
                     /locus_tag="ACL3S0_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR1312905.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3377..4042
                     /locus_tag="ACL3S0_002061"
     CDS             3377..4042
                     /locus_tag="ACL3S0_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGR1312906.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4177..4335
                     /locus_tag="ACL3S0_002062"
     CDS             4177..4335
                     /locus_tag="ACL3S0_002062"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312907.1"
                     /translation="MKIKDQTRKLATGCSKQCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            4397..4936
                     /locus_tag="ACL3S0_002063"
     CDS             4397..4936
                     /locus_tag="ACL3S0_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR1312908.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            5036..5413
                     /locus_tag="ACL3S0_002064"
     CDS             5036..5413
                     /locus_tag="ACL3S0_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGR1312909.1"
                     /translation="MIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLDLSQVSHPKMRE
                     YLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQENPKVFQAIRKTMLSRLTKH
                     SVLPDRKLSNVVYQITKSVYGFN"
     gene            5529..>6416
                     /gene="pavB"
                     /locus_tag="ACL3S0_002065"
     CDS             5529..>6416
                     /gene="pavB"
                     /locus_tag="ACL3S0_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGR1312910.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLV"
BASE COUNT         1733 a         1223 c         1485 g         1975 t
ORIGIN      
        1 gcctgcggct aacttcctag tttgcacttt aattttcatt gagtattact tcatcttctc
       61 atgaaattga gtttttgccc agctcctctt gattattcta cttgaccggg ccaagcattc
      121 ataccacctt ctacgttggt aacggtgagg ccttgggagc tgagaaattg gcaggtagat
      181 gcagagcgga ctcctccttg acaaatgaca tagtattcat ggtcaggttt gagttctttg
      241 tagccttgct ctaaggtact taatggaaga tttttggcac ctggtgcatg tcctgcttgg
      301 aattcatgtg cttcacggac atcgataagt tctagatttt cattttggta ttttccataa
      361 aagtcagcca tgctgatact agtttccata ttctactcct tctgggttaa ccattttgta
      421 tagtgaataa gcgccgtcaa ggttttgggc ggtaaatcct gcttgcttga ggataggctc
      481 tgcgatatag ctgcgcaaac cactgtggca gctgacgatg taggcttgtt ttttgtccag
      541 ttcatcagct tcctccttga cactttgtca gtttttgata caatagtaca aaattagagg
      601 aggcaggcta tgattcagaa acatgcgatt cctattttag agtttgatga caatcctcag
      661 gcggttatca tgcccaatca cgaggggctg gacttgcagt tgccaaagaa gtgtgtttat
      721 gcatttttag gtgaggagat tgaccgctat gcaagggaag taggggcgga ttgtgtcggc
      781 gaattcgttt ctgctaccaa gacctatcca gtctatgtca tcaactacaa gggtgaggag
      841 gtctgtctgg ctcaggctcc tgttggctcc gctccagcag cccagtttat ggattggttg
      901 attggctatg gtgtggagca gattatctct actgggacct gtggtgtcct agctgatata
      961 gaggaaaatg cctttctagt ccctgttcgc gctttgcgag atgagggagc cagttaccac
     1021 tatgtggcac cttgtcgtta tatggaaatg cagccagagg ctattgctgc tattgaggaa
     1081 gttttggaag acagagggat tccttatgaa gaagtcatga cctggacgac agacggtttt
     1141 taccgagaaa cggctgaaaa ggtggcttat cgtaaggaag aaggctgtgc tgttgtggag
     1201 atggagtgtt ctgctcttgc ggcagtagct caattgcgtg gggttctctg gggtgaattg
     1261 ttgttcacag cagattctct agcggacttg gaccagtacg acagtcgtga ctggggctcg
     1321 gaagctttta ataaggcgct agaactgagt ttagcaagtg ttcaccacct ttagttgtac
     1381 tggcaaagga tttgttttat cataaaatgt ctagctcata cttttcaaaa atatgtttaa
     1441 acgaggtcac cttcctcttg tcctaggcat gttgaggttg ggaaaaatct ttaaaatcag
     1501 aaaaacgtat catatcaggt gatgaaaact ttgatactat gcgttttatg ttggtaagat
     1561 ttagagtgag atgaaatgat actcttcgaa aatcttttca aaccaggtca gcttcacctt
     1621 gccgtagata tgttactgac ttcgtcagtt ctatctgcaa cctcaaaaca gtgttttgag
     1681 ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagcaacc tgtgactagc
     1741 tttctaatcg atgccttgat tttcattgcc tataatcaaa aagagaaatt ttctcctgaa
     1801 aagcatatag agtagctggc gttaaaagct cctgtcttgc ttttttgacc tatagtcaca
     1861 tctatcaagt attgttcttg cctaagctat caataaaaag gtggcatttt ttaggcttgg
     1921 tgttagtgaa ttttgcctta tcctatctaa gtcatttcga gctttttatg gtacaatgga
     1981 aacatgttat tcaaattatc taaggaaaaa atagagctag gcttatctcg tttatcgcca
     2041 gcccgtcgta tttttttgag ttttgccttg gtcattttac taggctctct tcttttgagc
     2101 ttgccctttg tccaagttga aagctcacga gcgacttatt ttgatcatct tttcactgct
     2161 gtctctgcag tctgtgtgac aggtctctca acccttccag tagctcacac ctataatatc
     2221 tggggccaaa taatctgttt gctcttgatt cagatcggtg gtctagggct catgactttt
     2281 attggggttt tctatatcca gagcaagcaa aagcttagtc ttcgtagccg tgcaactatt
     2341 caggatagtt ttagttatgg agaaactcga tctttgagaa agtttgtcta ttctattttt
     2401 ctcacgacct ttttggttga gagcttggga gctattttgc ttagttttcg ccttattcct
     2461 caacttggct ggggacgtgg tctttttagt tccatttttc tagcgatctc agccttctgt
     2521 aatgccggtt ttgataattt agggagcacc agtttatttg cttttcagac cgatttactg
     2581 gtcaatctgg tgattgcagg cttgattatt acaggcggcc ttggttttat ggtctggttt
     2641 gatttggctg gtcatgtagg aagaaagaaa aaaggacgtc tgcactttca tacgaagctt
     2701 gtactattat tgactatagg tttgttgtta tttggaacag caactactct ctttcttgag
     2761 tggaacaatg ctggaacgat tggcaatctc cctgttgccg ataaggtttt agttagcttt
     2821 tttcaaacag tgacgatgcg aacagctggc ttttctacga tagattatac tcaggctcat
     2881 cctgtgactc ttttgattta tatcttacag atgtttctag gtggggcacc tggaggaaca
     2941 gctgggggac tcaagattac gacatttttt gtcctcttgg tctttgcacg aagtgagctt
     3001 ctaggcttgc ctcatgccaa tgttgcgaga cgaacgatcg cgccgcgaac ggttcaaaaa
     3061 tcctttagtg tctttattat ctttttgatg agcttcttga taggattgat tctgctaggg
     3121 ataacagcca aaggcaatcc tccctttatc cacctcgtat ttgaaaccat ttcagctctt
     3181 agtacagttg gtgtaacggc aaatctgact cctgaccttg ggaaattggc tctcagtgtt
     3241 atcatgccac ttatgtttat gggacgaatt ggtcccttga ccttgtttgt tagcttggca
     3301 gattaccatc cagaaaagaa agatatgatt cactatatga aagcagatat tagtattggt
     3361 taagaaagga aagagcatgt cagatcgtac gattggaatt ttgggcttgg gaatttttgg
     3421 gagcagtgtc ctagctgccc tagccaagca ggatatgaat attatcgcta ttgatgacca
     3481 cgcagagcgc atcaatcagt ttgagccagt tttggcgcgt ggagtgattg gtgacatcac
     3541 agatgaagaa ttattgagat cagcagggat tgatacctgc gataccgttg tagtcgcgac
     3601 aggtgaaaat ctggagtcga gtgtgcttgc ggttatgcac tgtaagagtt tgggggtacc
     3661 gactgttatt gctaaggtca aaagtcagac cgctaagaaa gtgctagaaa agattggagc
     3721 tgactcggtt atctcgccag agtatgaaat ggggcagtct ctagcacaga ccattctttt
     3781 ccataatagt gttgatgtct ttcagttgga taaaaatgtg tctatcgtgg agatgaaaat
     3841 tcctcagtct tgggcaggtc aaagtctgag taaattagac ctccgtggca aatacaatct
     3901 gaatattttg ggtttccgag agcaggaaaa ttccccattg gatgttgaat ttggaccaga
     3961 tgacctcttg aaagcagata cctatatttt ggcagtcatc aacaaccagt atttggatac
     4021 cctagtagca ttgaattcgt aaagagggat gacccctctt ttttgatgcc caagatggca
     4081 aatagagaca gaagcccctt gtcttctagt aaaagttctt caaaggctgg actttatggt
     4141 aaaatagaaa gaagtgacaa gagagagtaa tactcaatga aaatcaaaga tcaaactagg
     4201 aaactagcta cgggctgctc aaaacagtgt tttgaggttg tggatagaac tgacgaagtc
     4261 agctcaaaac actgttttga ggttgcagat agaactgacg aagtcagtaa catctatacg
     4321 gcaaggcgac gttgacgcgg tttgaagaga ttttcgaaga gtataagaaa aaatcagtcc
     4381 cctaaaggag cagattatga agttattgtc tatcgccatt tctagctata atgcagcagc
     4441 ctatcttcat tactgtgtgg agtcgctagt gattggtggt gagcaagttg ggattttgat
     4501 tatcaatgac gggtctcagg atcagactca ggaaatcgct gagtgtttag ctagcaagta
     4561 tcctaatatc gttagagcca tctatcagga aaataaaggc catggtggtg cggtcaatcg
     4621 tggcttggca gaggcttctg ggcgctattt taaagtagtt gacagtgatg actgggtgga
     4681 tcctcgtgcc tacttgaaaa ttcttgaaac cttgcaggaa cttgagagca aaggtcaaga
     4741 ggtggatgtc tttgtgacca attttgtcta tgaaaaggaa gggcagtctc gtaagaagag
     4801 tatgagttac gattcagtct tgcctgttcg gcagattttt ggctgggacc aggtcggaaa
     4861 tttctccaaa ggccagtata tcatgatgca ctcgctgatt tatcggacag atttgttgcg
     4921 tgctagccag ttctaactgc ctgaacatac tttttatgtc gataatctct ttgtctttac
     4981 gccccttcag caggtcaaga ccaggtacta tctgcctgtc gatttctatc gttatttgat
     5041 tgggcgtgag gaccagtctg tcaatgagca agtgatgatt aagtgcattg accagcaact
     5101 caaggtcaat cgactcttgg tagaccagct tgatttgtcc caagtgagtc atcctaaaat
     5161 gcgagaatat ctgctgaatc atattgaaat cacgacggtg atttccagta ccctgctcaa
     5221 ccgatctgaa acagcggagc atctggcaaa aaaacgccaa ttgtggacct atattcagca
     5281 ggaaaatcca aaagtctttc aggctattcg taagaccatg ttgagccgtt tgaccaaaca
     5341 ttctgtcttg ccagatcgca aactgtccaa tgtcgtctat caaatcacca aatctgttta
     5401 tggatttaat taatataagt gttttataag agggatttaa gaaaaatttt aactttttct
     5461 tagtcctttt taatttcagg agattatact agagtcatca aataaagaaa gactctaagg
     5521 agaatcctat gaaattcaat ccaaatcaaa gatatactcg ttggtctatt cgccgtctca
     5581 gtgtcggtgt tgcctcagtt gttgtggcta gtggcttctt tgtcctagtt ggtcagccaa
     5641 gttctgtacg tgccgatggg ctcaatccga ccccaggtca agtcttacct gaagagacat
     5701 cgggaacgaa agagggtgac ttatcagaaa aaccaggaga caccgttctc actcaagcga
     5761 aacctgaggg cgttactgga aatacgaatt cacttccgac acctacagaa agaactgaag
     5821 tgagcgagga aacaaactct tctagtctgg atacactttt tgaaaaagat gaagaagctc
     5881 aagaaaatcc agagctaaca gatgccttaa aagaaactgt agatacagct gatgtggatg
     5941 ggacacaagc aagtccagca gaaactactc ctgaacaagt aaaaggtgga gtgaaagaaa
     6001 atacaaaaga cagcatcgat gttcctgctg cttatcttga aaaagctgaa gggaaaggtc
     6061 ctttcactgc cggtgtaaac caagtaattc cttatgaact attcgctggt gatggtatgt
     6121 taactcgtct attactaaaa gcttcggata atgctccttg gtctgacaat ggtactgcta
     6181 aaaatcctgc tttacctcct cttgaaggat taacaaaagg gaaatacttc tatgaagtag
     6241 acttaaatgg caatactgtt ggtaaacaag gtcaagcttt aattgatcaa cttcgcgcta
     6301 atggtactca aacttataaa gctactgtta aagtttacgg aaataaagac ggtaaagctg
     6361 acttgactaa tctagttgct actaaaaatg tagacatcaa catcaatgga ttagtt
//
LOCUS       DBEJZV010000067         6222 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.67, whole genome shotgun sequence.
ACCESSION   DBEJZV010000067 DBEJZV010000000
VERSION     DBEJZV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6222
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.67"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            188..400
                     /locus_tag="ACL3S0_002066"
     CDS             188..400
                     /locus_tag="ACL3S0_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312911.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            773..898
                     /locus_tag="ACL3S0_002067"
     CDS             773..898
                     /locus_tag="ACL3S0_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312912.1"
                     /translation="MATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDGYLWA"
     gene            879..1124
                     /locus_tag="ACL3S0_002068"
     CDS             879..1124
                     /locus_tag="ACL3S0_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312913.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            1281..2339
                     /locus_tag="ACL3S0_002069"
     CDS             1281..2339
                     /locus_tag="ACL3S0_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312914.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFMFSYILLFVQ
                     SYLGSNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            2654..3631
                     /locus_tag="ACL3S0_002070"
     CDS             2654..3631
                     /locus_tag="ACL3S0_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312915.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLILFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            4008..4382
                     /locus_tag="ACL3S0_002071"
     CDS             4008..4382
                     /locus_tag="ACL3S0_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGR1312916.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALPAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            4389..4571
                     /locus_tag="ACL3S0_002072"
     CDS             4389..4571
                     /locus_tag="ACL3S0_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312917.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWINVV
                     FLILIIAMMIYPKLRK"
     gene            4590..5492
                     /locus_tag="ACL3S0_002073"
     CDS             4590..5492
                     /locus_tag="ACL3S0_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312918.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            5548..5901
                     /locus_tag="ACL3S0_002074"
     CDS             5548..5901
                     /locus_tag="ACL3S0_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR1312919.1"
                     /translation="MDLVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            5898..>6222
                     /locus_tag="ACL3S0_002075"
     CDS             5898..>6222
                     /locus_tag="ACL3S0_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312920.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFA"
BASE COUNT         2064 a          779 c         1096 g         2283 t
ORIGIN      
        1 aaaggaattc gaattattta aaaataagaa atgagataga tatggtagct ttattaaaac
       61 tgagaataaa gtttgggaga tatttttatt tattttaggt gtgttgttaa ttgtaatttc
      121 attactaagt cccccaaaaa ttaaattttg gaaatagagt tagtgagaag gataggataa
      181 tagtattatg atggttgttt taatttcagt tattgttgca ttcctgtatc ataaaattac
      241 agagtatgtc aacaacagga aaattgatat tgttattttt ctatcattgc tgatttctca
      301 ttttatttgg aattactatt ttttaccaat tgaaatattg atagcaatca gtggagcaaa
      361 tttactatta agttttttaa aaaaattaca gactaaataa tattaatctg tgtaatacag
      421 tagctcggtc attagattct attgaagata taaattaaaa atgaggctgg gaaaaaactc
      481 aatttgaaaa tgaaattgag taaatttttc tattatataa cgcatattat caagattttt
      541 gaacacctga taatatgcac ttttcttatt ttaaagattt tttgcctttc ttcatttctt
      601 ggatgaattg gagagatgac ttgatttagg tgtttgacat tactatagat aggatttagc
      661 agtactaata tgaactcata ttataggtgt agacttaaat tttggaagca agctaaagga
      721 tatcttatct aggtaactaa gtgctataac aagatatatt ggtggagtta gtatggcaac
      781 tattactaat gctcttaata ttgcggctac tgttgctgaa gtcttctcat taggaggagc
      841 cattgcatat ggtttagata tcgtagacgg taaatttgat gggtatttat gggcgtaaaa
      901 ctatagctat gaaacatttt tttgcaggaa ttggtgaaat tcattttttg ttatttttat
      961 tatatctaag catgtctgct agtccaatta ttggactagt gattggatat actaaaataa
     1021 atctaataaa ttctattatt atagctcttg gtatgatatt ggcattaatt ttggtattat
     1081 caagagtgta tagaaaatat ttttatagag acgatgatga ctaaagtttt tatcaataat
     1141 ttgggctcct tgtcaactgt agtgggttga ataaaagcta acgtctgggg aagggtttaa
     1201 agctttgctt tatcaaatat tgacttacag agttgctcta ttgtattgat gtattcttag
     1261 taaataatat ggtgttttga atgaaagatg atcagaaata tttattagcg ggactttatt
     1321 cgcttctagt tgcaatattt tattttccat tgattgattc caaggggatt tttgtaagta
     1381 tattgatggc ggttttactt ttatatttaa tatacttcat tgcaacagtc attcatattg
     1441 tgataattaa gtttataaga aaaaaatctt ttaagtattt ggttctatat ccatttactt
     1501 acgatgggag ctggagattt cagcctataa acttactcta ctttccagaa atggtgagag
     1561 atgtcattcc gattaattta gttcaagaat attgccaagg acaaccttac ggactgttaa
     1621 aaaagatgct gaaaagaatt cgattgtcac gagagatatc tttactcctg gctaccatta
     1681 tcgtctattt ttttacgcat agaattctac ctctttcagt atttacgttc atgttctctt
     1741 acatattgct atttgtacaa tcttatttgg gtagcaatac cgcttggatt ggaaatagaa
     1801 gattaataat agatgatgaa tttgaaaaaa tcttgctttc aaaaagttat gtaaaagaaa
     1861 tatcatctgc acgatactca gaatacttga catgtgaata caaaaacctt acaccaatca
     1921 tattgatagc tatttttgaa aatttgcttg actcctactt gcttcagaat cagagtgagg
     1981 ttgacttaga tattttttat aaagttttac ctttgcttta taaagaaaaa tatactatgg
     2041 gattcaatta ctttgtaagt ttaaattatt tactatataa ggttggattt ttgggaatca
     2101 tttacgataa tgaagcatta agagatttgt caaaacaata tttaaacaaa aatatttcgg
     2161 aattacaaga tggttctttc gagggcggta tacaagatgc tgttgcctct aaacaaatag
     2221 tagttataaa tgaatttata gcttgtttaa attccagatg cgtgccatcc caatatgata
     2281 gattttttta taaagataga ccttatattt tttccagaaa gagtcctatt aaggggtgaa
     2341 aatttgttac atttggatta acaagtgtcc tagggattag aaataactct agtatagcta
     2401 gatatttttg agtaactaga aatatcatta ggctacccat atgattgcca gaaaagatgg
     2461 ctgatgaatc ttatttatac tgttgcagta ggcattgtct aggataaata agctatcttg
     2521 atgggggaga ttggaataat tttagtagaa acattaaagg attatggaca agtagcgtag
     2581 gattaggtga tgcaatgtgc taagttggct tggtgttagc agtagtatta tttaacaatg
     2641 gaaagtagac taaatgaaaa ataagcgtta tttttttgac acaattttaa taattttact
     2701 gcttataagc acgatatttt gtgtcagccc agtatttata aaattggaca tcttaggaac
     2761 tccctctcat gccatcttaa cctttgtatt ggcgataccg ttattctata ttttgtctca
     2821 atgcttacat actttgctat tactagtttc ctcaatcttt tgtaaattaa gaccaattta
     2881 tttttatttt atatttgtga tcattatagg agctaggaaa tactatcgaa ttctctttca
     2941 ccaactaatg ggatttagtc caggaatagc agtgttttat aaggagagtc aaacaactaa
     3001 gaatctgttt aaattttact acttcttgta ctttacaaca ctaatttcat actatttttt
     3061 ctttactttt gtgtatgaca aaccgttgct tttgcctctt attttatttt ctattatcat
     3121 agcattagta caaaaacttt atagaattga gaatcaacaa ttatttctgt taaaatcaaa
     3181 ggtactaaca atactggaat ctaagaagaa ttgtgagttt aatcttcagg attatcatga
     3241 aatttggaaa ttgcaatcaa aatctgagtt gccatgcgtg gctttatctt atatcagttt
     3301 aatcaagcca tatctttcag agagtgtgcg tgaacaaatt gatttattag aagttaagcg
     3361 atttaaaaaa ataaatcatc caatatcact ttatggtatg ttggatgtta taaaattaaa
     3421 tctatattta cggcattata atgaaaaaaa taaatatgaa tcaatgttaa agaaaatttt
     3481 agaggtaaga ccagactttg ttttaatcga gcagaatatt gatgatagtt taaatagctc
     3541 gcaaccatta tctttatctt tagccatttc agaaatccaa cttttgcttg aagtgtatat
     3601 agggatcaaa catgtttcaa ttaggagata aaactagaat aatatttgcc attatagggg
     3661 caagttgcat attagtcagt atgtatctta ttccacttat taaaactgag aataaatttt
     3721 gggaaatact tttatttata ttaggtgtat tgctaattgg aattgcgtta ctaagtcaaa
     3781 aaaaataaat tttgaaatag tattagtgag ttcgcaatca tttattgcta gtggtttaga
     3841 actgttaagt ttcaaacaat aattgatttt aaaccttagg taacctataa aaacaaataa
     3901 ggtagagaaa ggatatctta tctaggtagc taagtgataa aaacacagtc gtctatcact
     3961 tgttaggaaa ctatcctaac tatgcttaat aaaaaaggag aaaataaatg gaactcgtat
     4021 taccaaataa ttatgttgtt cttgagcaag aagagatgat gtatcttgat gggggatttt
     4081 ctattccgag atggcctgtt gcaacagcca ttaatatagc ttttaatggt gttttaggtg
     4141 gaggagcaat cagtctagtt agaaattata ttcgtaatta tggtttgcgg cgagttacaa
     4201 gcgcaattgc tggagcagct gcaagatatg ttggggtacg agttgcaaat agagtggcag
     4261 gatttgcact gcctgctatt aatggatttg cagcttggat gtcaattggc gatgctatta
     4321 caacaatctg ggccaataat gatgtaaata ggagagaccc aaatttaaac gccttgtggt
     4381 aactagatat gggtattaaa atggaaaaaa tttttgttat tatttttttt gtatgtctat
     4441 ttatatcatc cataactttt ttagcctatg attttgttag cgaagaaata aaaaagttga
     4501 ttatttggat taatgtcgtt tttttgattt taatcatagc aatgatgatt tatccaaaat
     4561 taagaaaatg ataaggacac tgtaaaatta tgatacgtaa actaattgtt ttcttactaa
     4621 tgctccctct ttttgtcttg tggctagagt tgcatgtcct agtgaataac ttactattga
     4681 atctagaatc tccccttgat tttgtgatta gtatgagtct tgctttctgt agtttgattt
     4741 tatcaaaaat agttttagac atactatacg cattgaaaga tttatacaag aaagaaggtc
     4801 ttattaagat ttttcccttt atttttataa gaaggaaaaa agtgaatgtg agattctcgc
     4861 cctatttttc attccatcgt aaaagtttgt cgcctgatga tttaagatct aggattatat
     4921 ggagttttat tcttgaaatt gctattatcc tagtatttat tttaaaaatt ccttttgcaa
     4981 tcatcatgct tactacaata tttttctgga ctataatgga tatcaatcat ctcgttttta
     5041 ataagacgga atttcttttc aatcaaaata aatgggaaaa agaagattcg tttgaaagtg
     5101 atttgacaaa tacgttaaag gataaaatac aaaaatcaga tctcagttat tctgacttaa
     5161 tgtctcttca gctgtatgat gcgatgaacc aatccacctt tttaacggat agtgaactct
     5221 ttgaggatat tctgagtaaa attgaagatt ctcataacac ccttctgtgt acaggtcttg
     5281 tcgagttact gctgtatgag atttctatta gtaacaataa caactggcaa gaaaaggttg
     5341 ataaaattag aatacagctc atcagaataa atcaattaga ttttttctat tatacaagtt
     5401 ggttaaggca aaattttgat ttctgtatga atagagagta tcataaaatg aaatctcgga
     5461 aattattact gagtaataaa aagatagttt aagttcgtcc tatttgtaaa acaaatgaaa
     5521 caatttcaac taaggaggag aaaacttatg gacttagtat taccaaataa ttatgttgtg
     5581 attgatgaag aagaaatgat gtatcttgat gggggagctt atttaagcaa gcgtgcttgt
     5641 caaggaattt gcgcagcttt agctatgagt tcaggaactt ttatagcatt agctggagct
     5701 gcagttttaa ccaaaaaact aataaactat attaaggttg gaggtcttgg aggctggctt
     5761 attggtgcag cagcaggtgt attggctaca gcagcaggga aaatagctta ctgtattgga
     5821 tatggtgttc ttaatagagg ttgtgatatt aacgggaacc cttatccttg ggatggattc
     5881 atatctgcaa cagtaagatg agtaatgtag ataagattcg aaaaatacac atcatcgtgt
     5941 gttgggtgta tatattttta tcattcaggg cgattataaa tgatacggag tattttttgc
     6001 ttattttttt agcttttatc tactcaatag tatcactacc tctatattct gtgaaaaata
     6061 aaatagtatc tatctgtcta gccataaatt cgattctgtt aatgagtttc cccattttaa
     6121 tcaataagtt tttcccagaa agttttttga cttataccgt attaataagt gtttttatcc
     6181 tagagttagc aatctttcat ttaattgggg aagattttgc ta
//
LOCUS       DBEJZV010000068         6094 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.68, whole genome shotgun sequence.
ACCESSION   DBEJZV010000068 DBEJZV010000000
VERSION     DBEJZV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.68"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            257..457
                     /locus_tag="ACL3S0_002076"
     CDS             257..457
                     /locus_tag="ACL3S0_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312921.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            482..898
                     /locus_tag="ACL3S0_002077"
     CDS             482..898
                     /locus_tag="ACL3S0_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
                     /protein_id="HGR1312922.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGMEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1129..1836
                     /gene="ccdA2"
                     /locus_tag="ACL3S0_002078"
     CDS             1129..1836
                     /gene="ccdA2"
                     /locus_tag="ACL3S0_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR1312923.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1847..2404
                     /gene="sdbB"
                     /locus_tag="ACL3S0_002079"
     CDS             1847..2404
                     /gene="sdbB"
                     /locus_tag="ACL3S0_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGR1312924.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGQEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2778..4169
                     /locus_tag="ACL3S0_002080"
     CDS             2778..4169
                     /locus_tag="ACL3S0_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGR1312925.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4312..5229
                     /gene="adcAII"
                     /locus_tag="ACL3S0_002081"
     CDS             4312..5229
                     /gene="adcAII"
                     /locus_tag="ACL3S0_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGR1312926.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5237..>6094
                     /gene="phtD"
                     /locus_tag="ACL3S0_002082"
     CDS             5237..>6094
                     /gene="phtD"
                     /locus_tag="ACL3S0_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HGR1312927.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVLKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLS"
BASE COUNT         1859 a         1106 c         1291 g         1838 t
ORIGIN      
        1 tacgaagaga cgatgacgag cgactttttt gaagcttggt ttcagaagtt tctcttacca
       61 acattaacca caccatcggt tattagagta aaatgaaata agaacaggac aaatcgatca
      121 ggacagtaaa atcgaattct aacaatgttt tagaagtcta tatgtactat tctagtttca
      181 atataccata actgctccta gtcaacctgc aagtcctgtc ccagctccaa gctcagctcc
      241 gactcaagat cctagagtgg tagcaagcgc ttcggctagc tcaacgagca cacaagctca
      301 agagcaagtt gacaagtctg aacttcgtgc cttgagtcaa gagttagacc aacgcttgaa
      361 agctttggca acagtatctg atccaaaaat cgatgcaacc aaggctgtcc tcctagatgc
      421 tcaaaaagct ccggaagata gtgccttgac agagtaaggt ctgcatactg cagtagagtc
      481 tgtgaaggct gccttggact ctctcaaaga tgtgaaagca aatgctagcg acagcaagcc
      541 tgcacaggac aagaaggatg caaaacaagg aatggaagat agtaaggatt cagataagat
      601 gactgaaaca aactcagttc cggcaggagt gattgtggtc agtctacttg ccctcctagg
      661 cgtgattgcc ttctggctga ttcgccgtaa gaaagagtca gaaatccagc aattaagcac
      721 ggaattgatc aaggttctag gacagctaga tgcagaaaaa gcggataaaa aagtccttgc
      781 caaagcccaa aaccttctcc aagaaaccct tgatttcgtg aaagaagaaa atggctcagc
      841 agagacagaa actaaactag tagaggagct taaagcaatc cttgacaaac tcaagtaaaa
      901 catgatttat gaaatgtcag acctaaaaga cattttcgtt cacaaaagca gtgacgagta
      961 atccttgtcg ttgctttttg gctattttgg gggataagat ccgccttgac tagcaaaaga
     1021 aaagattggt ccaatagtgc ccgatacgat tttgcgtagc agaaagctta caaataaaat
     1081 tgaatatagt aaaataggat tagaattatt aagaaagttg gttctttatt ggaaacgata
     1141 gtatttttaa tctctgtttt tctagcaggt gttttatcct ttttttctcc ttgtattttt
     1201 cctcttctgc cagtctatgc tgggatttta ttggatgatc aagaaagtgc aaaaagcttt
     1261 tctttgtttg ggagaaaggt tctctggtca ggcttgattc gaacactttg ctttatcgct
     1321 ggtatctctc tcattttctt tattctaggc tttggtgctg gttactttgg tcatattctc
     1381 tatgcaaatt ggtttcgata tgtcatggga gctattatta tcattttggg tcttcaccag
     1441 atggaaattt ttcatttgaa gaaattagaa gttcaaaaaa gttttacctt taaaaaatca
     1501 gattctaatc gttattggtc agctttttta cttggtatta cctttagctt tggttggaca
     1561 ccttgtattg gtccagtttt aagttctgtt ttagcacttg cggcttctgg aggcaatggt
     1621 gcttggcaag gagcgattta tactctcatt tacactctgg gcatggccct tcctttcttg
     1681 gtcttggcac tagcttcagg tctagtcatg ccatatttta gtaaaatcaa gcgtcatatg
     1741 atgctactaa agaaaattgg tggtttcctc attgttttaa tgggaatttt gttactatta
     1801 ggacaagtaa atgttctagc tggaattttt gaataaagga ggacaaatga aaaaagtaat
     1861 gtttgctggc ttaagtctct tgtcattagt tgtattgatg gcctgtggtc aggaagaaac
     1921 taaaaagact caagcagcac aacagccaaa acaacaaacg actgtacaac aaattgctgt
     1981 tggaaaagat gctccagact ttacattgca atccatggat ggcaaagaag ttaagttatc
     2041 tgattttaag ggtaaaaagg tttacttgaa gttttgggct tcatggtgtg gtccatgcaa
     2101 gaaaagtatg ccagagttga tggaactagc ggcgaaacca gatcgtgatt tcgaaattct
     2161 tactgtcatt gcaccaggaa ttcaaggtga aaaaactgtt gagcaattcc cacaatggtt
     2221 ccaggaacaa ggatataagg atatcccagt tctttatgat accaaagcaa ccaccttcca
     2281 agcttatcaa attcgaagca ttcctacaga atatttaatt gatagccaag gaaagattgg
     2341 aaagattcaa tttggtgcta tcagtaatgc ggatgcagaa gcagcattta aagaaatgaa
     2401 ctagaatcga taaaatctga ttacaagatg tagtcagatt ttggtaactt ctaaaactaa
     2461 cttccagttt cccacaactt agcttttagt atgagaaaaa cgcgtgacat cagtggaaat
     2521 ccgtcttaga ctaactttca ctggttttct ttttcttgat atataagggt tcaaaagcga
     2581 aaagactcag aaaaagtgca cgacaaatag ccctaaaaca gagtcgtctt agagtaactt
     2641 ccagttttgg gagagagatg gaagttactt tgagaagtta cggtagtcag atttttttag
     2701 aaaaacattt tataaatatt cacatatctc ctatatttat ggtaaaatag aattatcagt
     2761 ttattttgga gtcaaagatg aatatattta gaacaaagaa tgttagttta gataaaacag
     2821 agatgcatag gcatttgaag ttatgggatt tgattttgct gggtatcgga gccatggtag
     2881 ggacaggcgt ctttacaatc acaggtactg cagctgcaac acttgctggc ccagccctag
     2941 tgatttcaat cgttatttct gccttgtgtg tgggattatc agccctcttt tttgcagaat
     3001 ttgcctcgcg agtacccgct acaggaggtg cctatagtta cctctatgct atcttaggag
     3061 aattccctgc ctggttggct ggttggttaa ccatgatgga gttcatgaca gccatatcag
     3121 gcgtagcttc gggttgggca gcttatttta aaggcttgct ctctcaatac gggatagccc
     3181 ttcctcaggc tttaaatggt acctttaatc ctcaagcagg gacatttgtt gatttattgc
     3241 ctattcttgt cttggtcttg gtgacttcgc ttgttttact aaatgccaag gcagccttac
     3301 gctttaattc gattctagtt attttgaaat tttccgcttt agctctcttt gttttagtag
     3361 gaatttggaa tattaagttt gataattgga gcaattttgc tccttacggt tttggacaaa
     3421 tctatggagc tagcactggt attatggctg gtgcgtcctt gatgttcttc ggttttttgg
     3481 gatttgaatc catctctatg gctgtagatg aagtcaagac tcctcaaaaa aatattccta
     3541 gagggattgt cttatcgctt tctatcgtaa ccattctcta tgccttggtg acccttgttt
     3601 tgactggtgt ggttcactat agtcatttaa atgtcgatga tgccgttgcc tttgcccttc
     3661 gtagtgttgg gattagttgg gcagccaact atgtgtcatt agtggctatc ttgaccttga
     3721 ttacagtttg tatttcgatg acctatgccc tatcgcgtat gatttacagt ttagcacgtg
     3781 acggcttagt gcctgctgcc tttaaggaac tgacgaagac tagcaagata ccaaagaatg
     3841 ctactatctt gacaggtcta gcttcagcag tagcagcagg aatgttccca ctagccagta
     3901 ttgcagcctt tttaaatatt tgtaccttag cctacttgat catgttggct tatggtctga
     3961 ttcgcttacg gaaagaaaaa ggaatgccca aagctgggga atttaaaaca ccattggtac
     4021 ctctgttacc aattttatcg atcatcattt gtttatcctt catgttacag tataatatga
     4081 atacctggat tgctttccta gttgcgttgt tagtaggaag tattatttac ttcacttatg
     4141 gctataagca ttctaccata gaagaataaa gtgaaagtct attgagttgt tgacactcag
     4201 cagattttta tatgtgaaag aaatttcaaa ttttttctaa aaatatcttg acagattaaa
     4261 ttttcaggag tagaatattt actagttaat taaatggtta aggagttgtt catgaagaaa
     4321 caaaatttat ttttagtcct gttaagtgtc tttcttttgt gcttgggggc ttgtggtcaa
     4381 aaggaaagtc agacaggaaa ggggatgaaa attgtgacca gtttttatcc tatctacgct
     4441 atggttaagg aagtatctgg tgacttgaat gatgttcgga tgattcagtc aagtagtggt
     4501 attcactcct ttgaaccttc ggcaaatgat atcgcagcca tctatgatgc agatgtcttt
     4561 gtttaccatt ctcatacact cgaatcttgg gcaggaagtc tggatccaaa tctaaaaaaa
     4621 tccaaagtga aggtcttaga ggcttctgag ggaatgacct tggaacgtgt ccctggacta
     4681 gaggatgtgg aagcagggga tggagttgat gaaaaaacgc tctatgaccc tcacacatgg
     4741 ctagatcctg aaaaagctgg agaagaagcc caaattatcg ctgataaact ttcagaggtg
     4801 gatagtgagc ataaagagac ttatcaaaaa aatgcgcaag cctttatcaa aaaagctcag
     4861 gaattgacta agaaattcca accaaaattt gaaaaagcga ctcagaaaac atttgtaaca
     4921 caacatacag ccttttctta tctagcgaag agatttgggc ttaatcaact tggtattgca
     4981 ggtatctctc ctgaacaaga accaagtcca cgacaactaa cagaaattca ggaatttgtt
     5041 aagacctata aggttaaaac gatttttaca gaaagtaacg cttcttcaaa agtagctgaa
     5101 actcttgtca aatcaacagg tgtgggtctt aaaactctga atcctttaga gtcagaccca
     5161 caaaatgaca agacctattt agaaaatctg gaagaaaata tgagtattct agcagaagaa
     5221 ttaaagtgag gaaagaatga aaatcaataa aaaatatcta gcaggttcag tggcagtcct
     5281 tgccctaagt gtttgttcct atgaacttgg tcgtcaccaa gctggtcagg ttaagaaaga
     5341 gtctaatcga gtttcttata tagatggtga tcaggctggt caaaaggcag aaaatttgac
     5401 accagatgaa gtcagtaaga gggaggggat caacgccgaa caaatcgtca tcaagattac
     5461 ggatcaaggt tatgtgacct ctcatggaga ccattatcat tactataatg gcaaggtccc
     5521 ttatgatgcc atcatcagtg aagagctcct catgaaagat ccgaattatc agttgaagga
     5581 ttcagacatt gtcaatgaaa tcaagggtgg ttatgtcctt aaggtaaacg gtaaatacta
     5641 tgtttacctt aaggatgcgg cccatgcgga caatattcgg acaaaagaag agattaaacg
     5701 tcagaagcag gaacgcagtc ataatcacaa ctcaagagca gataatgctg ttgctgcagc
     5761 cagagcccaa ggacgttata caacggatga tgggtatatc ttcaatgcat ctgatatcat
     5821 tgaagatacg ggcgatgcct atatcgttcc tcacggcgac cattaccatt acattcctaa
     5881 gaatgagtta tcagctagcg agttagctgc tgcccaagcc tattggaatg ggaagcaggg
     5941 atctcgtcct tcttcaagtt ctagttataa tgcaaatcca gctcaaccaa gattgtcaga
     6001 gaaccacaat ctgactgtca ctccaactta tcatcaaaat caaggggaaa acatttcaag
     6061 ccttttacgt gaattgtatg ctaaaccctt atca
//
LOCUS       DBEJZV010000069         5062 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.69, whole genome shotgun sequence.
ACCESSION   DBEJZV010000069 DBEJZV010000000
VERSION     DBEJZV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.69"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            138..500
                     /locus_tag="ACL3S0_002083"
     CDS             138..500
                     /locus_tag="ACL3S0_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGR1312928.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            899..1144
                     /locus_tag="ACL3S0_002084"
     CDS             899..1144
                     /locus_tag="ACL3S0_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312929.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFIKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            1545..2537
                     /locus_tag="ACL3S0_002085"
     CDS             1545..2537
                     /locus_tag="ACL3S0_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1312930.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2539..3357
                     /locus_tag="ACL3S0_002086"
     CDS             2539..3357
                     /locus_tag="ACL3S0_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312931.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3359..4144
                     /locus_tag="ACL3S0_002087"
     CDS             3359..4144
                     /locus_tag="ACL3S0_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1312932.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4242..4460
                     /locus_tag="ACL3S0_002088"
     CDS             4242..4460
                     /locus_tag="ACL3S0_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGR1312933.1"
                     /translation="MKDLPEWFGIPESTQTYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4445..4642
                     /locus_tag="ACL3S0_002089"
     CDS             4445..4642
                     /locus_tag="ACL3S0_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1312934.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1453 a          847 c         1049 g         1713 t
ORIGIN      
        1 cgtcagttct atccacaacc tcaaaacagt gttttgagct gactacgtca gttccatcta
       61 caacctcaaa acagtgtttt gagcaacctg aggctagttt cctagtttgc tctttggttt
      121 tcattgagta taacagattg ttagaagttg gtttaaattt cctaatcagt ttgttcacat
      181 ttaccttcga tatattatat cccatagtta aggttggtca tacagatgat tatagtcatg
      241 gagccgtaaa acttagtgtt tctttagttg acaaagatgc catgaaaaaa atatctgtaa
      301 ctgtaatagg atattttgaa ataaatatag atgaaaatat caccgatatt ctatacgtaa
      361 atggtactgc tattctttat cattatttac gttctattgt ttcaatagtt tcggcaattg
      421 atagcagtga agcaatgttg ctacctacca ttaatgtttt agagttacta gataaatctc
      481 aaccttttga agaagaataa tttattagct cactaaattg agggtaagga aaagtaaaat
      541 cagtaagaaa aatgtcttgc attatacagc aaccttttgg gaatgagtag atggattgaa
      601 taaaatttta ttaagagtgg atgatttatc tgtagattat tattggacag ttagtcttga
      661 agtagtctaa gaattaggtt ataatcagta gaatccttgc taataatgag gaggttagtt
      721 tatgtatagt agactgaatc taaaatagta cgaaacaatt gctaaaacat ttatagaaat
      781 taattttact ttcccaatcg atttgttctc atcttatttc aatccgctat atattatggt
      841 atcgaatctt catcagaatg ataaaattaa tcaattgata tctgattaca aacagaatat
      901 gaaagctttt tatatcacta ttgaaaaatt tatacgagat gatgaaagcc ttaagtgtta
      961 ttttataaag gttatttcaa gtcgttccaa ggtaacaagt ctagatcaga ttgaagctga
     1021 taaaacgata caaagaaaat attcaagtga gctaaaaaaa tttattggat tttataatga
     1081 gattatttgt gaggaaaata gtttcctaca tgtacgaaag aggtggtcga gttggtttag
     1141 gtagtcgatg cgtgagttga taattctcag ggtatggact tctttttcat gaatgaggta
     1201 aaagagcagg tattgtttag agacaatcat tctgagcata ttttctggat agagggagta
     1261 tccgatttta tgatcaaagt taataccgcc ctctggtgag aagatgagta ggttggtaat
     1321 ttaaactatt aaacagaatt tttgattaaa agtattattt tatgagagaa atcctaattt
     1381 cacaatccat aggcaaactc ttgcatttcg ttttttattg gactataata ggttggtata
     1441 aagccttttg tagtaataaa atgtagaagg tgtagaaagc aaggatttag aatatttgta
     1501 gttaaaaaca caatgttgct attccttacg atagggagat agatatggca atgatagaag
     1561 tggaacatct tcagaaaaat tttgtgaaga ctgttaagga accgggcttg aagggggctt
     1621 tgcgctcctt tattcatcct gaaaagcaga cctttgaagc ggtcaaggat ttgacctttg
     1681 aggttccaaa agggcagatt ttaggattta tcggggcaaa tggtgctggg aagtcgacaa
     1741 ccattaaaat gctgacagga attttgaaac caacatctgg tttttgtcgg attaacggca
     1801 agattcccca ggacaatcgg caagattatg tcaaagatat tggcgtagtc tttggacaac
     1861 gcacccagct atggtgggat ttggctctgc aagagaccta cactgtctta aaagagattt
     1921 atgatgtgcc aaactcgctc tttcataagc gcatggactt tttgaatgaa gtcttggatt
     1981 tgaaggactt tatcaaggat cccgtgcgga ctctttcact gggacaacgg atgcgggcgg
     2041 atattgcggc ctccttgctc cacaatccca aggttctttt tttagatgag ccgaccattg
     2101 gtttggacgt ttcggttaag gataatattc gtcgggcaat tactcagatc aatcaagagg
     2161 aagaaactac cattcttttg accactcacg atttgagtga tattgagcaa ctttgtgatc
     2221 ggattttcat gattgacaag gggcaagaga tttttgatgg aacggtgagc caactcaagg
     2281 agacctttgg taagatgaag actctctctt ttgaactgct accaggtcaa agtcatctcg
     2341 tctctcacta tgaaggtctg tctgatatga ccattgatag acaaggaaac agcctcaaca
     2401 ttgaatttga tagttctcgc taccagtcag ctgacattat caagcaaacc ctgtctgatt
     2461 ttgaaatccg cgatttgaag atggtggata cggatattga ggatattatc cgtcgcttct
     2521 accgaaagga gctctaggat gatcaaattg tggagacgtt ataaaccctt tatcaatgca
     2581 ggggttcagg agttgattac ttaccgagtc aactttattc tctatcggat tggcgatgtc
     2641 atgggggctt ttgtggcctt ttatctctgg aaggctgtct ttgattcttc gcaagagtct
     2701 ttgattcagg gcttcagtat ggcggatatc accctctaca tcatcatgag ttttgtgacc
     2761 aatcttctga ctagatccga ttcgtccttt atgattgggg aggaggtcaa ggatggctcc
     2821 attatcatgc gtttgttgcg accagtgcat tttgcggcct cctatctttt caccgagctt
     2881 ggttccaagt ggttgatttt tatcagcgtt ggccttccat ttttaagtgt cattgtcttg
     2941 atgaaaatca tatcgggtca aggtattgta gaggtgctag gattaactgt cctttatctt
     3001 tttagcttaa cgctcgccta tctgattaac tttttcttta atatttgctt tggattttca
     3061 gcctttgtgt ttaaaaatct ttggggttcc aacctactta agacttccat agtggctttt
     3121 atgtcgggga gtttgattcc cttggcattc tttccaaagg ttgtttcaga tattctttcc
     3181 tttttgcctt tttcatcctt gatttatact ccagttatga tcattgttgg aaaatacgat
     3241 gccagtcaga ttcttcaggc actccttttg cagttcttct ggctcttagt gatggtggga
     3301 ttgtctcagt tgatttggaa acgggtccag tcctttatca ccattcaagg aggttagtat
     3361 gaaaaaatat caacgaatgc atctgatttt tatcagacaa tacatcaaac aaatcatgga
     3421 atataaggtg gattttgtgg ttggtgtctt gggagtcttt ctggctcaag gcttgaatct
     3481 cttgtttctc aatgtcatct ttcaacatat tccattccta gaaggttgga cctttcaaga
     3541 gatagctttc atttatggat tttccttgat tcccaaggga atggaccatc tcttttttga
     3601 caatctctgg gcactagggc aacgcctagt ccgaaaagga gagtttgaca agtatctgac
     3661 tcgtcccatc aatcctctct ttcacatcct agttgaaacc tttcagattg atgccttggg
     3721 tgaactctta gtcggtggta ttttattggg aacaacagtg accagcattg tttggactct
     3781 tccaaaattt ctgcttttcc tagtttgtat tccttttgcg accttgattt atacttctct
     3841 taaaatcgca acagccagta tcgccttttg gactaagcag tcaggcgcca tgatttacat
     3901 cttctatatg ttcaatgact ttgctaagta tccgatttct atttacaatt ctcttcttcg
     3961 ttggttgatt agctttatcg tgcctttcgc ctttacagcc tactatccag ctagctattt
     4021 cttacaggaa aaggatgtgt tctttaacgt aggaggtttg atgttgattt ctctggtttt
     4081 ctttgttatt tcccttaaac tttgggataa gggcttagat tcctacgaaa gtgcgggttc
     4141 gtaaaagcta aagtaagact aaaatcaaga aaggaactta tgatgtttgt aattgaagaa
     4201 gtcaaggatg aaaatcaaaa aaggcagttg tcgctgagat tttgaaggat ttgccagaat
     4261 ggtttggaat cccagaaagc acacaaacct atatagaagg aaccacgaca ctgcaagttt
     4321 ggaccgccta tcaggagagt gatttgactg gatttgtaag cttatcctat tcgagtgaag
     4381 attgtgcaga gattgattgt ctcggcgtaa aaaagcttat caaggtagaa aaattgggag
     4441 ccaattgctt gctactttag agagtgaagc tcgtaaaaaa gttggttatc tgcaggtcaa
     4501 aacagtggca gaagcttcta ataaagatta tgatcgaaca aatgactttt atcgaggtct
     4561 tggctttaaa aagttagaga tttttcctca actatggaat ccgcaaaatc cttgtcagat
     4621 tttgattaaa aagcttgaat aatattactt gacatctatt ttttattctc agagtgctat
     4681 actgtaagtg taatcgccga tttagctcag ttggtagagc aaggcactcg taaagcctag
     4741 gttataggta gataaacgac tgaggagttg aaaaaataga taggtagaag ataaccgtta
     4801 agccttattc ttagcggtta tttatattgt ttaatagcgc tgatatttca tcaattatgc
     4861 ctgttttcgt gtttccggta gttgttcaag tttattgcta ctatttttga tggtatgaat
     4921 gtgcttataa tgtatcccgg ttaacgaaag ttttggactt atactcttag aaaatctctt
     4981 caaaccacgt caacgccgcc ttgccgtgcg tatggttact gacttcgtca gttctatcca
     5041 caaccttaaa acagtgtttt ga
//
LOCUS       DBEJZV010000070         4663 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.70, whole genome shotgun sequence.
ACCESSION   DBEJZV010000070 DBEJZV010000000
VERSION     DBEJZV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.70"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..1341
                     /locus_tag="ACL3S0_002090"
     rRNA            <1..1341
                     /locus_tag="ACL3S0_002090"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1393..1465
                     /locus_tag="ACL3S0_002091"
     tRNA            1393..1465
                     /locus_tag="ACL3S0_002091"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1426..1428,aa:Ala,seq:tgc)
     gene            1590..4491
                     /locus_tag="ACL3S0_002092"
     rRNA            1590..4491
                     /locus_tag="ACL3S0_002092"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4568..>4663
                     /gene="rrf"
                     /locus_tag="ACL3S0_002093"
     rRNA            4568..>4663
                     /gene="rrf"
                     /locus_tag="ACL3S0_002093"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1291 a          961 c         1383 g         1028 t
ORIGIN      
        1 aaaaggtgca cttgcatcac taccagatgg acctgcgttg tattagctag ttggtggggt
       61 aacggctcac caaggcgacg atacatagcc gacctgagag ggtgatcggc cacactggga
      121 ctgagacacg gcccagactc ctacgggagg cagcagtagg gaatcttcgg caatggacgg
      181 aagtctgacc gagcaacgcc gcgtgagtga agaaggtttt cggatcgtaa agctctgttg
      241 taagagaaga atgagtgtga gagtggaaag ttcacactgt gacggtatct taccagaaag
      301 ggacggctaa ctacgtgcca gcagccgcgg taatacgtag gtcccgagcg ttgtccggat
      361 ttattgggcg taaagcgagc gcaggcggtt agataagtct gaagttaaag gctgtggctt
      421 aaccatagta ggctttggaa actgtttaac ttgagtgcaa gaggggagag tggaattcca
      481 tgtgtagcgg tgaaatgcgt agatatatgg aggaacaccg gtggcgaaag cggctctctg
      541 gcttgtaact gacgctgagg ctcgaaagcg tggggagcaa acaggattag ataccctggt
      601 agtccacgct gtaaacgatg agtgctaggt gttagaccct ttccggggtt tagtgccgta
      661 gctaacgcat taagcactcc gcctggggag tacgaccgca aggttgaaac tcaaaggaat
      721 tgacgggggc ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc
      781 ttaccaggtc ttgacatccc tctgaccgct ctagagatag agctttcctt cgggacagag
      841 gtgacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc
      901 aacgagcgca acccctattg ttagttgcca tcatttagtt gggcactcta gcgagactgc
      961 cggtaataaa ccggaggaag gtggggatga cgtcaaatca tcatgcccct tatgacctgg
     1021 gctacacacg tgctacaatg gctggtacaa cgagtcgcaa gccggtgacg gcaagctaat
     1081 ctcttaaagc cagtctcagt tcggattgta ggctgcaact cgcctacatg aagtcggaat
     1141 cgctagtaat cgcggatcag cacgccgcgg tgaatacgtt cccgggcctt gtacacaccg
     1201 cccgtcacac cacgagagtt tgtaacaccc gaagtcggtg aggtaaccgt aaggagccag
     1261 ccgcctaagg tgggatagat gattggggtg aagtcgtaac aaggtagccg tatcggaagg
     1321 tgcggctgga tcacctcctt tctaaggata aggaactgcg cattggtctt gtttagtctt
     1381 gagaggtctt gtggggcctt agctcagctg ggagagcgcc tgctttgcac gcaggaggtc
     1441 agcggttcga tcccgctagg ctccattggt gagagatcac caagtaatgc acattgaaaa
     1501 ttgaatatct atatcaaata gtaacaagaa aataaaccga aaacgctgta gtattaataa
     1561 gagtttatga ctgaaaggtc agaaaataag gttaagttaa taagggcgca cggtggatgc
     1621 cttggcacta ggagccgacg aaggacgtga caaacgacga tatgccttgg gtagctgtaa
     1681 gtaagcgatg atccagggat ttccgaatgg gggaacccaa caggtagtac ctgttaccca
     1741 catctgttaa ggatgtgagg aggaagacgc agtgaactga aacatctaag tagctgcagg
     1801 aagagaaagc aaaagcgatt gccttagtag cggcgagcga aacggcagga gggcaaaccg
     1861 aagagtttac tcttcggggt tgtaggactg caatgtggac tcaaagatta tagaagaatg
     1921 atttgggaag atcagccaaa gagagtaata gcctcgtatt taaaatagtc tttgtactta
     1981 gcagtatcct gagtacggcg ggacacgtga aatcccgtcg gaatctggga ggaccatctc
     2041 ccaaccctaa atactcccta gtgaccgata gtgaaccagt accgtgaggg aaaggtgaaa
     2101 agcaccccgg gaggggagtg aaatagaacc tgaaaccgtg tgcctacaac aagttcgagc
     2161 ccgttaatgg gtgagagcgt gccttttgta gaatgaaccg gcgagttacg ttatgatgcg
     2221 aggttaagtt gaagagacgg agccgtaggg aaaccgagtc tgaatagggc gccttagtat
     2281 catgacgtag acccgaaacc atgtgaccta cccatgagca ggttgaaggt gcggtaagac
     2341 gcactggagg accgaaccag ggcacgttga aaagtgcttg gatgacttgt gggtagcgga
     2401 gaaattccaa acgaacttgg agatagctgg ttctctccga aatagcttta gggctagcgt
     2461 cgacattaga gattcttgga ggtagagcac tgtttgggtg aggggtccat cccggattac
     2521 caatctcaga taaactccga atgccaatga attatggtcg gcagtcagac tgcgagtgct
     2581 aagatccgta gtcgaaaggg aaacagccca gaccaccagc taaggtccca aaataattgt
     2641 taagtggaaa aggatgtggg gttgcacaga caactaggat gttagcttag aagcagctat
     2701 tcattcaaag agtgcgtaat agctcactag tcgagtgacc ctgcgccgaa aatgtaccgg
     2761 ggctaaaaca atttaccgaa gctgtggata cctttatagg tatggtagga gagcgttcta
     2821 tgtgtgatga aggtataccg tgaggagtgc tggaacgcat agaagtgaga atgccggtat
     2881 gagtagcgaa agacaggtga gaatcctgtc caccgtaaga ctaaggtttc caggggaagg
     2941 ctcgtccgcc ctgggttagt cgggacctaa ggagagaccg aaaggtgtat ccgatggaca
     3001 acaggttgat attcctgtac tagagtatgt agtgatggag ggacgcagta ggctaactaa
     3061 agcagacgat tggaagagtc tgtctaagca gtgaggtgtg aattgagtca aatgcttaat
     3121 tctataacat tgagctgtga tggggagcga agtttagtag cgaagttagt gacgtcacac
     3181 tgccaagaaa agcttctagc gtttaaacat actctacccg taccgcaaac cgacacaggt
     3241 agtcgaggcg agtagcctca ggtgagcgag agaactctcg ttaaggaact cggcaaaatg
     3301 accccgtaac ttcgggagaa ggggtgctga cttaaagtca gccgcagtga ataggcccaa
     3361 gcaactgttt atcaaaaaca cagctctctg ctaaatcgta agatgatgta tagggggtga
     3421 cgcctgcccg gtgctggaag gttaagagga gtgcttagcg taagcgaagg tatgaattga
     3481 agccccagta aacggcggcc gtaactataa cggtcctaag gtagcgaaat tccttgtcgg
     3541 gtaagttccg acccgcacga aaggcgtaat gatttgggca ctgtctcaac gagagactcg
     3601 gtgaaatttt agtacctgtg aagatgcagg ttacccgcga caggacggaa agaccccatg
     3661 gagctttact gcagtttgat attgagtgtc tgtaccacat gtacaggata ggtaggagtc
     3721 taagagatcg ggacgccagt ttcgaaggag acgctgttgg gatactaccc ttgtgttatg
     3781 gccactctaa cccagatagg tgatccctat cggagacagt gtctgacggg cagtttgact
     3841 ggggcggtcg cctcctaaaa ggtaacggag gcgcccaaag gttccctcag aatggttgga
     3901 aatcattcgc agagtgtaaa ggtataaggg agcttgactg cgagagctac aactcgagca
     3961 gggacgaaag tcgggcttag tgatccggtg gttccgtatg gaagggccat cgctcaacgg
     4021 ataaaagcta ccctggggat aacaggctta tctcccccaa gagttcacat cgacggggag
     4081 gtttggcacc tcgatgtcgg ctcgtcgcat cctggggctg tagtcggtcc caagggttgg
     4141 gctgttcgcc cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag acagttcggt
     4201 ccctatccgt cgcgggcgta ggaaatttga gaggatctgc tcctagtacg agaggaccag
     4261 agtggactta ccgctggtgt accagttgtc ttgccaaagg catcgctggg tagctatgta
     4321 gggaagggat aaacgctgaa agcatctaag tgtgaaaccc acctcaagat gagatttccc
     4381 atgattatat atcagtaaga gccctgagag atgatcaggt agataggtta gaagtggaag
     4441 tgtggcgaca catgtagcgg actaatacta atagctcgag gacttatcca aagtaactga
     4501 gaatatgaaa gcgaacggtt ttcttgattt gaatagatat tcaattttga gtaggtatta
     4561 ctcagagtta agtgacgata gcctaggaga tacacctgta cccatgccga acacagaagt
     4621 taagccctag aacgccggaa gtagttgggg gttgccccct gtg
//
LOCUS       DBEJZV010000071         4511 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.71, whole genome shotgun sequence.
ACCESSION   DBEJZV010000071 DBEJZV010000000
VERSION     DBEJZV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.71"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(105..542)
                     /locus_tag="ACL3S0_002094"
     CDS             complement(105..542)
                     /locus_tag="ACL3S0_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGR1312935.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(627..3260)
                     /gene="polA"
                     /locus_tag="ACL3S0_002095"
     CDS             complement(627..3260)
                     /gene="polA"
                     /locus_tag="ACL3S0_002095"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGR1312936.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPVLLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3516..4423
                     /locus_tag="ACL3S0_002096"
                     /pseudo
     CDS             3516..4423
                     /locus_tag="ACL3S0_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
BASE COUNT         1362 a         1091 c          835 g         1223 t
ORIGIN      
        1 caacctcaaa acagtgtttt gagcagcccg cggctagttt cctagtttgc tctttgattt
       61 tcattgagta taacacaaaa ggtagcccat cagctacctt tttcttatgc ttcctcaatc
      121 aagcgagtat gttctctctt gatacagcga ttcatcacga tatcatcaca tccaccatca
      181 cgcaaaatct ctttcgcttc taaactttca agtcctagct gtgcccaaaa aatcttggca
      241 tcagctttga gaaaatcacg cgccacatcg ggcagaaatt cactgcgacg ataaacattg
      301 acaatatcta caggaaaagg aatttcagcg aggctagcat aagccttttc acccaagatt
      361 tcgccacctg ccgccttggg attgactggg atgattttat agccccgagc ctgcatttcc
      421 tttgtcactc gattgctggt tgtttcttca cggtcagaca aacccaccac agcaagggtt
      481 ttactcgttg cgagatactg acgaatcacg ccatcacttg gattgataaa ttcttgactc
      541 atagaaaacc tcctttttca tcagtatagc acattttgaa aaggtttgca gaattctact
      601 acaaaaaagg aggactagcc ccctttttat ttagcctcgt accaggttgc cccttcattc
      661 tcatctgcga taagaggaac actgagttga atggcttctt ccatggtttg tttcaccaat
      721 tttttcatct ctaccaattc agatttaggc acttcaagga cgatttcatc gtgcacttgt
      781 aacagcatct tagtctgata accacctgca accaaggctt tatccagctg aatcatggca
      841 atcttgagaa tatctgctgc cgaaccctgg ataggtgagt tgatagcagt tcgctccgca
      901 aaaccacgaa tattgaagtt gcgcgaattg atatctggca actcacggcg acgcttaaag
      961 agggtctcta catagccctt atcacgcgcc tcccgcacca cttcatccat gtagttttta
     1021 atacctggaa aacgttcaaa gtaggtatca atgtaggctt tggcttcctt acgactaatt
     1081 cccaaattat tagacaagcc aaagtctgaa atcccataaa ccactccaaa gttaactgcc
     1141 ttggcattgc gacggtcatt tgcagtcaca ttatcaggac gctcaatgcc aaagacccgc
     1201 atggctgtcg aagtatggat atctgccccc tcttggaagg ccttaatcaa gtgctcatcc
     1261 ttagaaatat gcgccaaaac gcgcaattca atctgtgaat agtcagagct gagtagcaca
     1321 ctatcctccc actctggcac aaaagccttc cgaatcaagc gcccctgttc caatcgggca
     1381 ggaatatttt gcaagtttgg atccacacta gacaaacgcc cggtctgggt caaatcctgc
     1441 acatagcgag tatgaatctt tccatcagcc aaaatccagt cctgcaagcc aattacataa
     1501 gtagattgaa tcttagcaat ttgacggtaa tccaggattt tcttaacaat cggagcaata
     1561 ggagcgagac gctccaacac atccactgct gtcgaataac ctgtcttggt tttcttagtg
     1621 tattctagag gaagtcccaa tttctcaaag agaagcacgc ccaactgctt aggcgagttg
     1681 acattaaact cctcaccagc cagctcgtaa atctcttgag tcagtttttc aatgacaagc
     1741 tcattttcag cctgcatctc aagcaaggtc tctttcttga ccacaatccc agcaatttcc
     1801 atcttggcaa gaacaaaagc cagaggttgc tccatatcat aaagaagctc taattgccca
     1861 ttttcgctga gtttttcaag tagaacaggc tctgtttcta ccaaaacagc aagtttacaa
     1921 gctaagtgtt ccaagaattt ctcacgttca ggaatggcct ttttaacacc cttaccgtag
     1981 aaagtttcat catcaaccaa gtaagtctga ccataaagac tagcgatggt cgcaatttca
     2041 ttgtcctcca cagtcgaaag gaggtattta gccaaacgga tgtcaaaagc aggcgcctgc
     2101 aaatccacac caaaacgttg caaaagaact ttaaccttct taaagtcata aactctcaga
     2161 gatgtttttt ctaagaaatc cttgaaaatc gggtcttgca acagctcaag cttgtctgtg
     2221 gcatagagct tatccccaca agaccaggca aatccaacca aattatccgt atggtaattc
     2281 tcaccaaaaa gctcaaagtg gaagatagac tcttcactca gcatatcttg actgatttgg
     2341 tcaacaatag taaaatccaa accctcagcc acatcagctg acgacacatt taaagcctgc
     2401 ttgagctgtt tgaatcccat ctcatcgtaa aatttcccaa gattttcaac atctggacca
     2461 ctatagacca agtcctctaa accaatcgca atcggtgcct tggtatcaat ggtcgctagt
     2521 gttttagaca aaaaggcctg ttccttgtca ttgatgagat tttccttcat cttagaagtc
     2581 ttcattccat caatattttc ataaatcccc tcaagcgaac catgctccag caagagctta
     2641 atacccgtct tttcaccgac tttggtcacc ccagggatat tatccgactt atcacccatg
     2701 agcgccttga gatcgataaa ctgagctggt gtgaggccca tttcttccat gaggtaatct
     2761 ggcgtaaagg cctcaaactc agccacacct ttcttggaaa tttcaaccac cgtatgctca
     2821 tccgtcagct gaatcaaatc cttgtcccca ctgacaatgg taatatcaaa accatcctgc
     2881 tctgctagct tatccagcgt cccaatgatg tcatccgcct catactgagc cagctcatag
     2941 tgacgaatcc ccatatgatc cagcaactca cgaatgaaag gaaattgctc acgaaactca
     3001 tcaggagtct tggcccgacc acccttatag tccgcataca tctctgtccg gaaggtcgtc
     3061 tttcccgcat caaaagccac caaaatatga ctcggctcaa cccgctccaa caaatgactc
     3121 aacatcaact gaaaaccata aatcgcattg gtatgcaaac cagccgcatt cttaaaacgg
     3181 tccaactgct gatacagcgc aaaaaacgcc cgaaaagcta cagaagaccc atcaatcaat
     3241 aataattttt tcttatccat acacccatta taaaggaaag aatcaaaaaa taccattggg
     3301 aagagctaga gctagtattt ttcaaacttt ttccgaataa atagatagag ccagagaatt
     3361 tagtaaacct agatttaaaa atgtgctata atatagtata ttgaatctat aatagtacac
     3421 cttgactgct aaaatatttc tataaattaa tttgactttc ctgatagagt tattcacatc
     3481 ttatttcaac tcactataga aggaggaata ggaggattct cagacatccg ggcatcagcc
     3541 caactaatga tttgattgct aagaaaatat tcagcaatcc agaaatcact tgtcaattta
     3601 ttcgcgatat gctggacttg ccagcaaaaa atgtgaccat tttggaggga agcgatattc
     3661 acgtattact ctccatgcct tactcggtgc aggattttta taccagtata gacgtcttgg
     3721 cggagttgga taacggtact caagtaatta ttgagattca agtccatcat cagaattttt
     3781 tcatcaatca cttgtgggct tacctgtgca gtcaggttaa tcaaaatctt gaaaaaattc
     3841 gtcagcgaga aggtgatact cactagagct acaaacacat cgctcctgtt tacgccattg
     3901 ctatcgtgga tagtaattat ttctcagatg acctggcttt tcatagcttt agtatgcgcg
     3961 aagacacaac aggtgaggta ttggcgatta ccaacaatgg acaggaaaac catctggtta
     4021 agatggcatt cttggaatta aaaaatacag agaaaccagc aaagacaagg ttcgcaagcc
     4081 atggttggag tttttcggca acaagccctt tacccagcaa ccgcaacgag ccattaccca
     4141 agcaaatcaa ctgctggact acaagagctg gtccgaggag gacaggaaaa tgtttaatca
     4201 actacatatg cgagaagaac aagtcttgtt agcacaggac tatgccttgg aaactgctag
     4261 ggctgaaggc cttgaacaag gattagagcg tgggaaagtt gaaggaaggg cagaaaggaa
     4321 actttttacc ttcctagaca tagtacgcca aggtcttctg acttctgagg ttgccagcca
     4381 gcaattaggt atgtcagtat ctgaatttga ggcactgttg taaaatggct ccataatatc
     4441 catagtgggt aaatccccta tggatattat ggagcctatt ttgtgtagaa aaaaagtccc
     4501 atatgaccta t
//
LOCUS       DBEJZV010000072         4298 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.72, whole genome shotgun sequence.
ACCESSION   DBEJZV010000072 DBEJZV010000000
VERSION     DBEJZV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4298
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.72"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(68..316)
                     /locus_tag="ACL3S0_002097"
     CDS             complement(68..316)
                     /locus_tag="ACL3S0_002097"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR1312937.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDK"
     gene            complement(493..708)
                     /locus_tag="ACL3S0_002098"
     CDS             complement(493..708)
                     /locus_tag="ACL3S0_002098"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HGR1312938.1"
                     /translation="MEPKIRNSDYLFIKNTPQIDYNTIGIFQVDGANYVKKLRQGYLK
                     KTQSRIPRHPPRRKQPYSYHRESCQAI"
     gene            1556..2428
                     /locus_tag="ACL3S0_002099"
     CDS             1556..2428
                     /locus_tag="ACL3S0_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGR1312939.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHVTSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2574..2918)
                     /locus_tag="ACL3S0_002100"
                     /pseudo
     CDS             complement(2574..2918)
                     /locus_tag="ACL3S0_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3061..3372
                     /locus_tag="ACL3S0_002101"
     CDS             3061..3372
                     /locus_tag="ACL3S0_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312940.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIERPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            3376..4092
                     /locus_tag="ACL3S0_002102"
     CDS             3376..4092
                     /locus_tag="ACL3S0_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR1312941.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
BASE COUNT         1356 a          717 c          826 g         1399 t
ORIGIN      
        1 aaataagata tgcacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atcttaaatg cctttctcta aatttacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccctt
      481 ttttaattct ccctatatag cctgacaact ttcccgatgg tacgaatatg gttgctttcg
      541 tctaggtgga tgtcggggta ttcgggattg agtttttttg aggtagcctt ggcggagttt
      601 cttgacatag ttagcgccgt ctacttggaa gatgccgatg gtattatagt caatctgtgg
      661 ggtattcttg ataaataggt agtcgctgtt tcttatcttt ggctccatgg acttgctgac
      721 gacataagcg attgggtcgt agtcgtctgg gataatggaa actccataac taaatcgtcg
      781 tcctgcatcg agcggctacc tgcagagata aactacctaa cacgagagta agtagtctgt
      841 ctgtagtcgt ccagtctgat gatttttacg atacttcgtt tttctgatca tacagttgcc
      901 tctcggcata ggtcagaact ttaccttgtc tgggtggtgc ccgttggtcg tagatagatt
      961 ggatatcgct aggagaatcc ttttgaactg gagaaaagag ggcatcaatc aagctactga
     1021 atactttaac taagtcaaat atagtatttt tcttagtaga cctaaccctt ttttcataat
     1081 ttctaatggt gtttttactt atacctatct tagtacccaa ttcttattga gtccaaccat
     1141 tactagtcta tattgtttta tagttgattt agtttggaat agtacgctgt agctgctaaa
     1201 acatttctag gaattaattt gcctttccta atagagttgt tcatatctta tttcaatcta
     1261 ctatattttt cacctctaac aatcgcaatc tcttctttat ccatgaataa aaacgatttc
     1321 tatttttgta agtaaagcat cacacgaaat ccacgaaaat gaaaaccttt gttgtgtttt
     1381 cgtaaaaaat ttgttgacag agcacgaaac gcctactata attaaatcaa gtttaaggaa
     1441 ataacaaaaa aacaaatcgg agggaaagac gatgaacaca ttaaatgaga aagtaatcaa
     1501 tatctgtaaa gcagtagtta aagaaacttt aatccaagac atttaggaga aagaaatgaa
     1561 gaaatcaaga aaattagcca cattaggaat ctgttcagct ttgtttttag gcttggctgc
     1621 ttgtcaacaa caacatgtta cttctgaggg gacgaatcaa aggcaaagca gttcagcgaa
     1681 agttccatgg aaagcttcat acaccaacct aaacaaccag gtaagtacag aagaggtcaa
     1741 atctctctta tcagctcact tggatccaaa tagtgttgat gcatttttta atctcgttaa
     1801 tgactataat accattgtcg gctcaactgg cttatcagga gatttcactt cctttactca
     1861 caccgaatac gatgttgaga aaatcagtca tctctggaat caaaagaagg gcgatttcgt
     1921 tgggaccaac tgccgtatca atagttattg tcttttgaaa aattcagtca ccattccaaa
     1981 gcttgaaaag aatgaccaat tgcttttcct agataacgat gcgattgata aaggaaaggt
     2041 ctttgattca caagataagg aagagtttga tattctattt tcgagagttc caactgaggc
     2101 aactacagat gtcaaggttc acgctgaaaa gatggaaaca ttcttctcac aatttcaatt
     2161 caatgaaaaa gctcgaatgc tgtctgtagt cttgcacgac aatctggatg gcgagtatct
     2221 gtttgtaggc cacgttgggg tcttagtacc tgctgatgac ggtttcttat ttgtagagaa
     2281 attgactttc gaagagccct accaagcgat taaatttgct agtaaggaag attgctacaa
     2341 gtatttgggc accaagtatg cggattatac aggcgaggga ctggctaagc cttttatcat
     2401 ggataatgat aagtgggtta aactttaata gtgttatgat atgacagtaa tcttaggatt
     2461 tttatttcta tttttgatga cttggtgggt tatttcaatc gttaatagcc agaaaccacg
     2521 caaaaatgaa acatttattg gctatatcca aagatacgat attgatggga atggctatca
     2581 atcattaccg tgtcctcaga actgagagga gttcttgaaa tcgtaaaact actttgaaca
     2641 agagttactt caacccattg gctccgacgg attaagttgc tttcgtgaac accaaaatca
     2701 gccgcaattt cttcataagt gcggtattct cgcacatatt gaagagtggc cataagaagg
     2761 tcttctaggc ttaatttagg ttttcgtccc ccttttgtgt gtttaagttg ataagcagtt
     2821 tttaatacag ctaacatctc ttcaaaagtg gtgcgctgaa caccaacaag acatttaaat
     2881 cgtgcatcag ttagttgctt acttgcttca taattcatag aactactata ccatattttg
     2941 tttcgcagga agtctaatgc taaaatctta tcagtgagaa gatttcttaa agtttattct
     3001 ttgtagtttc atctgtatta gtatataatt taacttagag aaaataggag gactaatcga
     3061 atggaattaa aagattttac agaaaaagaa caggaaatga ttaagaaaag gcttacaatg
     3121 tctaatatta gtgacaaaga aactactgag aagattctgg cgctagtacc acaagacttg
     3181 attaagcgaa tcccgttttt tgtcagaaaa catgctacaa cacgtacgat taaacgcatt
     3241 tcaattgaac gccctgaact ctacgctgta gctcaaacaa gtggtgagat tccagaaaaa
     3301 gaacgcgaag aattgcgtca gattatcaca actatctttg aacaaaagat gaataagcat
     3361 agtattaagt agagaatgaa aaaatatttt attggcggtt tgggaagcaa tgcctatcat
     3421 agcaaggatt ttcttcaaga actagattcg caggtctatt ttctaaatcc atatgaaaag
     3481 catcttcgag atgaaacaga attgaaatca tggtttaaaa atgagattgt agaggaagaa
     3541 tctatctgtc tgataggtca ttctattgga ggcgatttag ctcgttattt cgcatcggaa
     3601 tttgaagaag taaagaaact gattcttttg gatggtggct atctagattt agataagatt
     3661 ttacctttgg atacagagtt agaggaaact aaaaattata tcaaatctca aattatttcg
     3721 gacttagatg ttcttacttc taaagaaaaa tctgaagcaa agcattggtc agaaaatatg
     3781 gagaaagctg taagacagtc ctatcactgg aatgttgagt ataatagata tgagttggct
     3841 ataaattatg aaaatataga agcgatactc cgcctacgga gaaaaataca agcttttaag
     3901 agagaagtgg gagatacctt gtttattagt cctcgctatc ctaatgaagc tacatggaga
     3961 gaggaagccc taaaagaatt gccagactat tttgatacta tttttttaga aaactttggc
     4021 catgagcttt atactcaagc acctaaagaa atcgctagtc taatgaatga gtggctcgct
     4081 tattttctat gagctacttg tattgctgga aatggtataa gatgaaaatc tacaagtcac
     4141 taattttcat ataaccaaaa aacgaacagg ctctttttct gggctctttg tcaactgtag
     4201 tgggttgaag tcagctaagc tcgagaaagg acaaattttg tcctttcttt tttgatattc
     4261 agagcgatga aaatccgttt tttgaagttt tcaaagtt
//
LOCUS       DBEJZV010000073         3808 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.73, whole genome shotgun sequence.
ACCESSION   DBEJZV010000073 DBEJZV010000000
VERSION     DBEJZV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3808
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.73"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..290
                     /locus_tag="ACL3S0_002103"
     CDS             <1..290
                     /locus_tag="ACL3S0_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312942.1"
                     /translation="YNIYRGFTHYKYYRAENSHLIYADYFEMKLQKLLKDDTKVFEKS
                     TFKFVEGYKIYLTESKESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(645..1178)
                     /locus_tag="ACL3S0_002104"
     CDS             complement(645..1178)
                     /locus_tag="ACL3S0_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGR1312943.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1267..2043)
                     /gene="recX"
                     /locus_tag="ACL3S0_002105"
     CDS             complement(1267..2043)
                     /gene="recX"
                     /locus_tag="ACL3S0_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGR1312944.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2081..3436
                     /gene="rlmD"
                     /locus_tag="ACL3S0_002106"
     CDS             2081..3436
                     /gene="rlmD"
                     /locus_tag="ACL3S0_002106"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR1312945.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            3498..3569
                     /locus_tag="ACL3S0_002107"
     tRNA            3498..3569
                     /locus_tag="ACL3S0_002107"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3531..3533,aa:Glu,seq:ttc)
BASE COUNT         1271 a          640 c          684 g         1213 t
ORIGIN      
        1 tctataatat ctatagggga tttacccact acaaatatta tagagccgaa aattcacatc
       61 taatatatgc agactacttt gaaatgaaat tacaaaaatt attaaaagat gacacaaaag
      121 tttttgaaaa atctacattc aaatttgtag aaggatataa aatatacctg acagaatcta
      181 aagaatctgg aattaaacaa atggacaatg tcataaaata ttttgagttt attgaatcta
      241 aaagtattgc tttatatttt caaaaacgat taaatgagct gatagattaa atatcatttt
      301 ctctgttaag atattgtttt taaaatattg tactaaatga ttgatgctat gtggaaatac
      361 aaaaaaatgt ttttgatacg aagttgacct gtatttttta tactaatcat tttcgtattt
      421 tttgtattaa acgatataag tttgttgtaa acttacaagg aataaagaca ttaaaaaata
      481 acagtatatc tatttgtttt atatatttta cgaattttgc ataaatctct ttctagtaat
      541 gtgttgtaac tctgctataa tagatttatt cctttttgtg tttacacaat ttattttata
      601 ctaccaaaaa aaggtcagga ttttgttcct gacctttgac aactttaccg attctttagt
      661 tctacatagc gcttgtacca aatgtttaca taggcttctg agaaaggacc acgtccattg
      721 ttaatccaat caacaagaat tttgacatgt tcttttaaaa tatagtccaa gtcatcagaa
      781 taattcattt tgcgtttgtg acgctcgtac tcttcaacgt ccaagagacg tttttcccca
      841 tctgtaaaaa ttttaacatc caaatcgtaa tcaatatact tcagtgcttc ttcatccaga
      901 tagtaggggc tagccatatt gcaatagtaa gaagttccat tatcacgaat catggcaatg
      961 atattaaacc aatatttctt gtgaaagtaa acaatagccg gttctcgagt gacccaacga
     1021 cgaccatcac tttcggtaac aagtgtatga tcgttgacac caataatggc gttttctgtt
     1081 gtttttagta ccatggtgtc ccgccaagtt cggtggagac tcccatcatg cttataactt
     1141 tgaattgtaa taaagtcgcc ttcttttgga agcttcataa ctaaccaact ttctacaatt
     1201 tataagttta tcatttacta ttgtaccata aaattaccta aaatctgtga atttcacttg
     1261 gaaatattaa agatattctc taagagcgct tgctatatcc gaaaaatcgt agccctttcg
     1321 tgctaaaact tgagttaaac gctgcttcag ttcgtatcct tcatactttc gagcatactt
     1381 agtatattgc ttatcaagtt ccttgaagat gagttcttga gtcgtttctt ggtcaacttg
     1441 gctatctaag tcgtcaaagg caattttagc atcagaataa gagaagccct tgttagtcaa
     1501 gttctggata atcttatctt gcagggcacg agctggaagt tttccctcat attttttcaa
     1561 tagtttattg gctacacgtt gagcaacttc cgaaaaatca aaatcattca agatttcttc
     1621 tatagtagat tttgaaattc ctttttgtgc taatttctga gtcagtacat aaggtccctt
     1681 gtctcctgaa agttgattgg cattgatgat agcataagcg tactgaccat cattaatcca
     1741 cttatcttct ttaagattag caataacttg agaaacgatg tttttatcaa tatcgtattt
     1801 tttcagatat tctctgactt ctttttcagt gcgtgcttta aaggataagt ggtagagggc
     1861 cagattctta ccataagaaa attgagcaaa gtcttgaatc tctttcaatt cctcttcgct
     1921 tatcacctta tctctcgata acataaaacg aacaattgta tcttcggtga tatagcattt
     1981 gtcgccatta tcaagctcca tcagatagag tctttttttc ttttcaagtt ttgtgatttt
     2041 catagctcta ttataactca aaatgtgata agataggggt atgaatctga aagtgaaaca
     2101 aaaaatacca ttaaaaatca agcgcatggg aattaacggt gagggaatcg gcttttacca
     2161 aaaaacatta gtctttgtac caggagctct caaaggcgaa gatatctatt gtcagattac
     2221 ttctattaga cgcaactttg ttgaagcaaa attactgaag gtcaacaaga agtctaaatt
     2281 tcgaattgtg ccatcttgta ctatttataa tgaatgcgga ggctgccaaa tcatgcacct
     2341 gcattatgat aagcagctgg agttcaagac ggacttactt catcaagcgc tgaaaaaatt
     2401 tgctcctgca ggatatgaaa attatgaaat tcgtccaact attggaatgc aggaaccaaa
     2461 atattacaga gctaagttac aatttcagac ccgaaaattt aaaaatcagg tcaaggcggg
     2521 cttatatgca caaaactctc actatttagt agagttgaaa gactgcctgg tacaagataa
     2581 ggaaacccaa gtgattgcta atcgcttagc agaattactt acttatcacc agattccaat
     2641 cacggatgag agaaaagttc taggtgtccg tactattatg gtccgacgcg cgagaaagac
     2701 cggacaggtt cagattatta ttgttacaaa ccgccagctt aatttaactc aattggtaaa
     2761 agagttggtt aaagatttcc cagaagttgt gacagtagct gttaatacaa atacagctaa
     2821 aaccagtgag atatatggtg aaaagacaga gattatctgg gggcaagaga gtattcaaga
     2881 aggtgtactc aattatgaat tttcactatc ccctcgagct ttttatcaac taaatcctga
     2941 gcaaacagaa gtcctctata gcgaagcagt aaaagcgctg gatgttgata aagaagacca
     3001 tttgattgac gcttattgtg gagttggaac gattggattt gcctttgcaa agaaagtaaa
     3061 aacactcaga ggtatggata ttattccaga agctattgaa gatgccaagc gaaatgctaa
     3121 aagaatggga tttgacaata ctcattatga agctggaacg gcagaagaga ttattcctcg
     3181 ttggtacaag gaaggctacc gagcagatgc tttgattgtt gacccaccac gtacaggtct
     3241 ggatgataag ttattagata ctattcttac ttatgtacca gaaaaaatgg tttatatttc
     3301 ttgtaatgtt tcgaccttgg ctcgtgattt ggtacgctta gtagaagtct atgatcttca
     3361 ttatatccag tcggtcgata tgttcccaca tacagctcga actgaagctg ttgtaaaatt
     3421 aataaaaaaa gtttaaaaaa ggtgttgaca aaacataaaa aggctgtata atagtaagag
     3481 ttgaaaataa caactcaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
     3541 taacacgggt tcgaatcccg tacggactat ggtatgttgc gtcaggagca cttgatgaaa
     3601 aaaagtttaa aaaaacttaa aaatcttcaa aaaagtgttg acaagtgaaa gtggctgtga
     3661 tatactaata tagttgtcgc ttgagagaag caagtgacaa agacctttga aaactgaaca
     3721 agacgaacca atgtgcaggg cgctacaacg taagttgtag tactgaacaa tgaaaaaaac
     3781 aataaatctg tcagtgacag aaatgagt
//
LOCUS       DBEJZV010000074         3554 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.74, whole genome shotgun sequence.
ACCESSION   DBEJZV010000074 DBEJZV010000000
VERSION     DBEJZV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3554
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.74"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(301..594)
                     /gene="rpmA"
                     /locus_tag="ACL3S0_002108"
     CDS             complement(301..594)
                     /gene="rpmA"
                     /locus_tag="ACL3S0_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGR1312946.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(611..955)
                     /locus_tag="ACL3S0_002109"
     CDS             complement(611..955)
                     /locus_tag="ACL3S0_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGR1312947.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(971..1285)
                     /gene="rplU"
                     /locus_tag="ACL3S0_002110"
     CDS             complement(971..1285)
                     /gene="rplU"
                     /locus_tag="ACL3S0_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGR1312948.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(1321..1408)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(1467..2170)
                     /locus_tag="ACL3S0_002111"
                     /pseudo
     CDS             complement(1467..2170)
                     /locus_tag="ACL3S0_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
     gene            2573..2872
                     /locus_tag="ACL3S0_002112"
     CDS             2573..2872
                     /locus_tag="ACL3S0_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGR1312949.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            3091..>3554
                     /locus_tag="ACL3S0_002113"
     CDS             3091..>3554
                     /locus_tag="ACL3S0_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGR1312950.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYEAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKNSMTDIAHQLAISTSTVIRKLNDFHFKHDFSRLPEIMS"
BASE COUNT         1162 a          720 c          610 g         1062 t
ORIGIN      
        1 ccatccagga tctaagctaa ggcaaggatt ctggatggtt tttagattag gggtgaataa
       61 ttggggttaa agtgcaaact aggaagttag ccgcaggctg tacttgagta cggcaaggtg
      121 aaactgacgt ggtttgaatt tgattttcga agagtatcaa tccactatac atattaaaag
      181 tatggatatc aaaacaaaaa aacaggctct ccgaaaactc ggaaagcctt attttaagct
      241 gtttctagct tcctcacctt tacatttcaa ggttcgggat aaaaggttca atggaccttt
      301 ttatttagcg attgggtaaa cagaaacttg ttttttatcg cgtcctttac gttcaaagcg
      361 tactacgcct tcaactttag cgaacaaagt atcgtctcca ccacgaccaa cgtttacacc
      421 tggatagatg tgtgtaccac gttgacggta aaggattgat ccacctgtta cagtttgtcc
      481 gtcagctgct ttagctccaa gacgtttcgc ttgtgaatca cgtccgtttg atgtagaacc
      541 tccacctttt ttgtgggcga aaagttgcaa gttgttaaga gtcattttta acataatgtt
      601 ttcctccgtg ttagttttct gtgataactc tggtttggac gaactcagaa gagttctccg
      661 ataagtttgc catacctaag aaaaatgatt caaagaataa ctgggtcatt tctctctggt
      721 gtgaaggaag atcttttggt atttcaacca tcagatagcc accttcatct tcgtttaatt
      781 ctaggattgg ttcatagcct gcaaatttct caatagaatt gataaagtta atggcaagcg
      841 tagaaaccga tgcacacacg acatctaagc cgtattcgcc actctcggcg tgtccagtaa
      901 tttccgcact cctcagctcg ccatcttcgg ctctctcaaa gactgcctgt atcatgtgtt
      961 ctccttaaaa ttaagcgttg attgcgttga tgacaacttt tgtatatggt tgacggtgac
     1021 cttgtttacg gtggctacct tttttaggtt tgtacttgta agtaaccact ttcttttgtt
     1081 ttccttgttt ttcaacagtt ccaactacag tagctccagc aacaagtgga gttccgacaa
     1141 cagtgttttc accaccaaca agaacaactt cgttaaaagt aacttcttga ccagcttcaa
     1201 cgttcaattt ttcaacgtaa actgcttgac caacttcaac tttaacttgt tttccgccag
     1261 ttttgataat tgcgtatgtg ctcattatgc acctcctatg atttttatgg gtttccccga
     1321 ttttttgtga agactcgcct agcatcgtgg gacgaaccac ttaaacttga ataatcaagc
     1381 aacgatgttc gtgcggttgc acaggatcgt gcatagtcaa ctcttcaagt atagcatatc
     1441 tcctattttc ttacaagtaa taacacctaa aatgaagctt tttcttttac ttttttctgc
     1501 caagaggcaa aaagcatgct gaggtaaaaa acgctcatca taataggaac accaagaatg
     1561 gtcttttcat gatagaaaat cgtcaaatag gctgaaaaga caacgccaag gacaaaacta
     1621 ctaagcaggc taacaaatat gaatccttca cgcaaaaaag gagtgtgctt ggttcggaaa
     1681 taatctccaa aagccagcat ggtccgtttg atattccctg tcataaaagc gttattatag
     1741 gcaatacccg acacttctcc aaaagcagtt gtcaccagtc ccatacagaa ggccaagggc
     1801 ggcactagat agatattatc tacagtttgt ggcacaaaac caataattat tgataggatt
     1861 gctaaaggaa tcaaggacag aatagatttt ttcacaattc tcaatttttc cttataaatc
     1921 gttaataaaa agactcccat cataaacgct attaaggtta aaagcttatc cctaatatcc
     1981 gaaacattat tttgtatgag ctctaccgaa agaaagacaa catttccagc ttgtccagct
     2041 acaaggatat tcccgcgaac aataaaagtg taagcatcca catatccagc acaaaacgtc
     2101 aaaaaagtgc taacctttta gactgacgtg atatttttct tataggtaat aacctcattt
     2161 tccctcccat tgtattttct cttagaaata ttgtaccatt ttctttctaa aaaatcgtag
     2221 gctaccattt agattttact attagcataa aaataataat agacaactat ttatccaaaa
     2281 atagatagag gtaacatgtt tgcaaacaaa gcatacgaac ctttagtaaa atcatttcca
     2341 tgaaactaga atagagcccc tcttagcaaa aatcattatt ttaatttatt tctaatcact
     2401 ccttgacata aataactctc accaataaaa gactatgtct taaaaaaatg gtataataaa
     2461 atcaatactt gggcttgatg gctatgctac taataacaat taggagagaa aatcaggcac
     2521 ttgttaacaa caaggattat ccccttgaga tgaaaggaac tttagaaatc ttatgatgaa
     2581 catgcaaaac atgatgcgtc aagcacaaaa acttcaaaaa caaatggaac aaagccaagc
     2641 tgaacttgct gctatgcaat ttgttggcaa atctgctcaa gatcttgtcc aagcaacctt
     2701 aactggcgat aagaaagttg tcagcattga tttcaatcca gctgtcgttg acccagaaga
     2761 ccttgagact ctttctgata tgaccgttca agccatcaac tctgctcttg aacaaatcga
     2821 tgaaactact aagaaaaaac tgggtgcttt cgctgggaaa ttgccattct aaaaacaagg
     2881 agctagaaca atgcttgtcg ataacaaagg ctaagaaagg tgcaaaaatt ataaaaaacg
     2941 catagtatca agcaacctaa aactttgggc tctataatat ttgtagtggg taaatcccct
     3001 atagatatta tggagcctat tttgtgtaga aaaaaagtcc catatgacct ataatgaaaa
     3061 gcgacaaaac aactcattag aaagaatcat atggaacaat tacattttat cacaaaatta
     3121 ctagacatta aagaccctaa tatccagatt ttagacatca tcaataagga tacacacaag
     3181 gaaatcatcg ccaaactgga ctatgaagct ccatcttgcc ctgagtgcgg aagtcaaatg
     3241 aagaaatatg actttcaaaa accttctaaa attccttatc ttgaaacaac tggtatgcct
     3301 actagaattc tccttagaaa gcgtcgtttc aagtgctatc attgttctaa aatgatggtt
     3361 gctgaaactt ctatcgtcaa gaagaatcat caaatccctc gtatcatcaa ccaaaagatt
     3421 gctcaaaagt taattgaaaa gaattctatg accgatattg cccatcagct ggccatctca
     3481 acttcaactg ttattcgtaa gctcaatgat tttcacttta aacatgattt ttcgcgtctt
     3541 cctgagatta tgtc
//
LOCUS       DBEJZV010000075         3355 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.75, whole genome shotgun sequence.
ACCESSION   DBEJZV010000075 DBEJZV010000000
VERSION     DBEJZV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.75"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            538..1884
                     /gene="gdhA"
                     /locus_tag="ACL3S0_002114"
     CDS             538..1884
                     /gene="gdhA"
                     /locus_tag="ACL3S0_002114"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGR1312951.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2390..2560)
                     /locus_tag="ACL3S0_002115"
     CDS             complement(2390..2560)
                     /locus_tag="ACL3S0_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312952.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2573..3145)
                     /locus_tag="ACL3S0_002116"
                     /pseudo
     CDS             complement(2573..3145)
                     /locus_tag="ACL3S0_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(3168..3355)
                     /locus_tag="ACL3S0_002117"
                     /pseudo
     CDS             complement(3168..3355)
                     /locus_tag="ACL3S0_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         1052 a          611 c          560 g         1132 t
ORIGIN      
        1 agatttgccc atcagacgaa atatagtaga ttgaaactag aatagtacac ctctacttct
       61 aaaacattgt tagaaatcga tttgtcctgt tctagtttca ttttactata gaacgatttg
      121 aaggcgttta taatatttag ctgtacgaga gtcttttaaa agtgttttga tggtttggat
      181 ttcttcttta gttgatttca tattactatt atataatgct ttttgatttt agtctggtat
      241 aaatattgct ttcctccaaa atggtcatag ttttactggc aaatctaaca tatcacggat
      301 aaattaacaa gtgatttctg aattgctaaa cattttcttt tcttatagca tactttaaga
      361 ttttgtcttt gagaaagata tttccaagaa aaacgttcgt ttttttatct attttcaaaa
      421 aaaccaaaaa actgaattga aagaattttt agaaaatttc tgttttttct ttacagtgaa
      481 aaaaaattct gctataatgt cttatgtaat aaaatatgac aataaaagga gaacgatatg
      541 acatctgcta aagaatatat ccaaagcgtg tttgaaactg tgaaagctcg taacgggcac
      601 gaggctgaat tcctccaagc tgttgaagaa tttttcaaca ctttagaacc tgtatttgaa
      661 aaacaccctg agtatatcga agaaaatatc ttggcacgta ttactgagcc tgagcgcgtg
      721 gtttctttcc gtgttccttg ggttgaccgt gatggaaaaa ttcaagtaaa ccgtggttac
      781 cgtgttcaat tcaactcagc tgttggacca tacaaaggtg gacttcgttt ccacccaact
      841 gtaaaccaag ggatcttgaa attcctcgga tttgaacaaa tctttaaaaa tgtcttgact
      901 ggacttccta tcggtggagg taaaggtgga tcagacttcg atcctaaagg taaaacagat
      961 gctgaagtga tgcgcttctg ccaaagcttc atgactgaat tgcaaaaaca catcggacca
     1021 tcacttgacg tacctgctgg tgatatcggt gttggtggac gtgaaattgg ttacctttac
     1081 ggtcaataca aacgtcttaa ccaatttgat gctggtgtct tgactggtaa acctcttgga
     1141 tttggtggta gcttgattcg tccagaagca actggttacg gtttggttta ctatactgaa
     1201 gaaatgctca aagctaacgg taacagcttt gctggtaaga aagtcgttat ttcaggttct
     1261 ggtaacgttg ctcaatatgc tcttcaaaaa gcaactgaac tcggtgcaac tgttatttct
     1321 gtttctgact caaatggtta tgtcatcgat gaaaatggta tcgacttcga tcttttggtt
     1381 gatgttaaag aaaaacgtcg tgctcgtttg actgagtatg cagctgaaaa agcaactgca
     1441 acctaccacg aaggtactgt atggacttac gctggaaact atgacattgc tcttccatgt
     1501 gccactcaaa acgaaatcaa cggtgaagca gctaaacgtt tggttgctca aggcgttatc
     1561 tgtgtatctg aaggtgccaa catgccgagc gaccttgatg ccatcaaagt ttacaaagaa
     1621 aatggtatct tctacggacc tgcaaaagct gccaacgctg gtggtgtagc cgtttcagct
     1681 cttgaaatga gccaaaacag tcttcgcctc tcatggactc gtgaagaagt tgatggccgt
     1741 ctcaaagaca tcatgacaaa catcttcaac acagctaaaa cgacttcaga aacatacggt
     1801 cttgataaag actaccttgc aggagctaac attgctgcct ttgaaaatgt agcaaatgcc
     1861 atgattgcac aaggtattgt ttaagattta tttactcaat cctcaatcac tacgattggg
     1921 gatttttagc ttgaattaaa aaattggaaa atctaattaa ataaaatgaa atgaaataaa
     1981 aactgaacaa attgattgcg gaattcaaac caatttctaa catatttcta gaaattaatt
     2041 tgacttttct aatcgatttg ttcatatctt atttcaattt actatactta cttgaccctt
     2101 tttatactca atgaaaatca aagagcaaac taggaagcga gccgcaggct gtacttgagt
     2161 acggtaaagc aaagctgacg tggtttgaag agattttcaa agagtattaa acaaaaagaa
     2221 aaaccgctac tcctaagaat agcgatttaa tcatgttttt aagctactac tgtagttgct
     2281 ctattattta agtgttatga ataacttcaa tatctttaaa gctttttgtt agatttataa
     2341 tttcaactat agccatctct actccttagt ttacagcaaa aaattatgct taattcttat
     2401 tgtttttgta aacaatcagc gaacccaata ctattccatt caacaagcct aaagaaatac
     2461 catattcaac tggaaaatct aaaaaaattg caaacactat tccaatcatc acccctagtg
     2521 aggctgttgt taaaattaca tattcatttt ctttcttcat tttctttaca cctcatttcc
     2581 tttttgtata taagctgtag tactctccac caagatccat taagtactta tgatttcctg
     2641 actcaacaat cttaccacct ttcattacaa aaataacatc cgcatcctta atcgttgaca
     2701 atctatgagc tacaattatt tgagtacagc cctgactttg tatatacttt gttattcttt
     2761 cctcattaat agtgtctaat gcactagttg cttcatctaa aattacaata ctaggattat
     2821 ttattaatgc acgtgccagt gctatccgtt gcctttgccc acctgaaata tttgacccca
     2881 tctctgagat gatagtatta aatttcatcg gcatagccat gatttcatca tagatttgaa
     2941 ctgctttaca aacttcctct atcttttgtg aagtaacttc gtgctttaaa gttatattat
     3001 caagaatact tcggttcaat aaaaatgaat cctgtggaac tactcctaaa ttttgactta
     3061 atattttttt atctatttga ttaatattta caccatcaaa taaaactttt cctgtatcaa
     3121 tcttatataa tcttgatggt atttttgata atagacttcc tgcaaaacta gaatcctagt
     3181 tcatgattga taataccagc aatcaaattc attcgtaatc cgaagcgttt agatgatttc
     3241 gataggttgt tgaaatcatt ttaaacgttt ttactttggc aaagatgttc tcaaccttgc
     3301 ttctctcctt agatagcgca tggttataga ctttatcttc aattgttagc ggttt
//
LOCUS       DBEJZV010000076         3300 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.76, whole genome shotgun sequence.
ACCESSION   DBEJZV010000076 DBEJZV010000000
VERSION     DBEJZV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3300
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.76"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            513..710
                     /locus_tag="ACL3S0_002118"
     CDS             513..710
                     /locus_tag="ACL3S0_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312953.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            1167..1406
                     /locus_tag="ACL3S0_002119"
     CDS             1167..1406
                     /locus_tag="ACL3S0_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312954.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            1391..1669
                     /locus_tag="ACL3S0_002120"
     CDS             1391..1669
                     /locus_tag="ACL3S0_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1312955.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            1955..>3300
                     /locus_tag="ACL3S0_002121"
     CDS             1955..>3300
                     /locus_tag="ACL3S0_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate hydrolase"
                     /protein_id="HGR1312956.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKSEAAKKHYEEVKKKAEDAQKKYDEGQKKTVEKAKREKEASEKIAEATKEV
                     QQAYLAYQQASNESQRKEADKKIKEATQRKDEAEAAFATIRTTIVVPEPSELAETKKK
                     AEEAKAEEKVAKRKYDYATLKVALAKKEVEAKELEIEKLQYEISTLEQEVATAQHQVD
                     NLKKLLAGADPDDGTEVIEAKLNKGEAELNAKQAELAKKQTELEKLLDSLDPEGKTQD
                     ELDKEAEEAELDKKADELQNKVADLEKEISNLEILLGGADSEDDTAALQNKLATKKAE
                     LEKTQKELDAALNELGPDGDEEETPAPAPQPEQPAPAPKPEQPTPAPKPEQPTPAPKP
                     EQPAPAPKPEQPAPAPKPEQPAPAPKPEQPTPAPKTGWKQENGMWYFYNTDGSMATG"
BASE COUNT         1221 a          496 c          658 g          925 t
ORIGIN      
        1 aaaggaatac gaattattta aaaatagcaa gtaatagaaa cataggttaa atcttagaac
       61 ggcttaaaat cagatatgat aaagggaaat agtcttatct aggtaactaa gtgctacaaa
      121 cacagtcgag gatcacttgt taggattaca ttttaatcat gcttaataag aatggagaat
      181 tcctatgggg attgtattac tctgaagttt cgaatacctt agttctcgtg attttgagct
      241 gttctagctt tagaatcctt cagaatgtaa aattttaagc agtcaaagac ttagaatagc
      301 ctggaaacat ttattttata gcaattctag gcttagaatt gctcatatat atgtatttga
      361 gctgctcgat agttaggaca gctctattct gagaaatctg agctatcaat gcttcagaat
      421 agtatttcgc aaatggtttt tattgaagag gtgattgttt tatgatagtc taaaataaaa
      481 ctgatttaat ggagtaaatg gagaatcgtc acatgaaaca tttttttgca ggaattggtg
      541 agataaaact tgttggctac ttattgtata tatgtgtagg actagcccct ctttttcata
      601 tatatgtcat aggttcggaa ctgagttttg tgaaaatagt gttatctatt ttgggagtta
      661 tatttgtaag tatgttaact attgctcgaa tttatcggac ttttctataa agaatagttt
      721 ggacttgaac tgtatctaaa aacagaggtt ggtcgattat cagcctcttt cttgtcgttg
      781 aaaagagtga gatatattga cttttgaaaa aaatgtcata attgagttgg gataaaccta
      841 aaagtaatat agtagattga atctggaata gtccgttatg actgttaaaa tatttctaga
      901 aattaatttg actttcctaa tcgatttgtt cacatcttgt ttcaatctac tatactttct
      961 cgttaaaccg ttcggcaatt catggtgaca tggacacata gtagtaagca cactatgtgg
     1021 cttggcagag ctaaaaactg ttcccttgcg ataagcctaa taagcacaac atagggagtt
     1081 agagaagccg actctaatca accactttgg gcagtagtga gaactgcccc gtgctttttt
     1141 attttgagaa aatatggagt ttgtcgttga aattacttga ttgtattttg gactatcaag
     1201 aaagattcaa tggaaaaaca tgtcaagtat caacgaatta taagtattta gagattttca
     1261 aagtgaattt ttgcttgact gatttacatc atttatttga cttatacaaa atcacacgag
     1321 attatgctag tcaaacaaaa cctgctattc aagctggtgt ttttatttta gaagatttta
     1381 gaaatatcct atgtacaatg atgtaatcga aaggatatct ttatatgagt ttatcggtga
     1441 tattttctat tctaaaataa taagttgttg catcgtagct agggatttat ctaaaaatac
     1501 tatgaaattg gacgtcatat tttttgagga taaaaataaa agatccgcag ttttaggttt
     1561 acgaagagac aaaagcggag tatttaaatc agttactcta cattttacaa gcgctaagaa
     1621 atatgctaaa gttcgtaaaa cagatgtgaa agaaatgaaa tggctataaa gattgtccgc
     1681 aggcttaagc ttgcgttttt tgttgtttaa cgaaattaaa aaataagctc tctcattgga
     1741 aatgttttta taggaatgaa ggaagatgat gctatgttta aaaagagaat cgaaaagggc
     1801 aaaagtagtg tctttatctt tttggagtag aagcttatga tatagaaatt tgtaataaaa
     1861 atgtaatata aaacatttga caaatattta cggggggagt atacttaata taagtatagt
     1921 ctaaaaatga ctatcagaaa agaggtaaat ttagatgaat aagaaaaaaa tgattttaac
     1981 aagtctagcc agcgtcgcta tcttaggggc tggttttgtt acgtctcagc ctacttttgt
     2041 aagagcagaa gaagctcccg tagctagtca gtctaaagct gagaaagact atgatgcagc
     2101 agtgaaaaaa tctgaagctg ctaagaaaca ttatgaagaa gttaaaaaga aagcagaaga
     2161 cgctcagaag aaatatgacg agggtcagaa gaaaacggta gaaaaagcaa agcgagaaaa
     2221 agaagcttct gaaaagatag ctgaggcaac aaaagaagtt caacaagcgt acctagctta
     2281 tcaacaagct agcaacgaaa gtcagagaaa agaggcagat aagaagataa aagaagctac
     2341 gcaacgcaaa gatgaggcgg aagctgcatt tgctactatt cgaacaacaa ttgtagttcc
     2401 tgaaccaagt gagttagctg agactaagaa aaaagcagaa gaagctaaag cagaagaaaa
     2461 agtagctaag agaaaatatg attatgcaac tctaaaggta gcactagcga agaaagaagt
     2521 agaggctaag gaacttgaaa ttgaaaaact tcaatatgaa atttctactt tggaacaaga
     2581 agttgctact gctcaacatc aagtagataa tttgaaaaaa cttcttgctg gtgcggatcc
     2641 tgatgatggc acagaagtta tagaagctaa attaaacaaa ggagaagctg agctaaacgc
     2701 taaacaagct gagttagcaa aaaaacaaac agaacttgaa aaacttcttg acagccttga
     2761 tcctgaaggt aagactcagg atgaattaga taaagaagca gaagaagctg agttggataa
     2821 aaaagctgat gaacttcaaa ataaagttgc tgatttagaa aaagaaatta gtaaccttga
     2881 aatattactt ggaggggctg attctgaaga tgatactgct gctcttcaaa ataaattagc
     2941 tactaaaaaa gctgaattgg aaaaaactca aaaagaatta gatgcagctc ttaatgagtt
     3001 aggccctgat ggagatgaag aagaaactcc agcgccggct cctcaaccag agcaaccagc
     3061 tcctgcacca aaaccagagc aaccaactcc tgcaccaaaa ccagagcaac caactcctgc
     3121 accaaaacca gagcaaccag ctcctgcacc aaaaccagag caaccagctc ctgcaccaaa
     3181 accagagcaa ccagctcctg caccaaaacc agagcaacca actcctgcac caaaaacagg
     3241 ctggaaacaa gaaaacggta tgtggtactt ctacaatact gatggttcaa tggctacagg
//
LOCUS       DBEJZV010000077         3047 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.77, whole genome shotgun sequence.
ACCESSION   DBEJZV010000077 DBEJZV010000000
VERSION     DBEJZV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3047
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.77"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            30..155
                     /locus_tag="ACL3S0_002122"
                     /pseudo
     CDS             30..155
                     /locus_tag="ACL3S0_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(127..1602)
                     /locus_tag="ACL3S0_002123"
     CDS             complement(127..1602)
                     /locus_tag="ACL3S0_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGR1312957.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2309..>3047
                     /locus_tag="ACL3S0_002124"
     CDS             2309..>3047
                     /locus_tag="ACL3S0_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR1312958.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFD"
BASE COUNT          943 a          647 c          579 g          878 t
ORIGIN      
        1 ttgaggcagg atttgataag ctgatagaaa ttaagcgatt gaccgcttct aattcaaggg
       61 ctttttgccg tgctctaaaa tcatcgccaa atcatcaaat tgaaataaga aatagtttag
      121 ataaaactat tgacttttct tatagtttgt ctttctctta atgacgttga tatgattgac
      181 ctctggatct tccgtccctt ggagggagca accacgttcc ttggcgaatt ggatatagtc
      241 gacaatttct cgtgtaatgc gttcaccagg agccaagata ggaatacctg gagggtaaca
      301 cataacaaat tctccacaga cctgtccaac agaatcatcc aaagttaaac tttttctttc
      361 tgaatagaag gcttcttgcg gagacagcac taactcgggc tgaatatatt ctcctgctat
      421 caaatctttt ccatctcttg aatagagtct cttaatatca gccagagcac caaccaagcg
      481 ctcgatgtct tggatgcggt cgccgatgga aatataggcc aagatattgc cgatatcacc
      541 aaactcgatc tgaatgtcgt attcgtctcg caagaggtca taaacctcga tacctgttaa
      601 gccaataccc tgagtgtaaa ctgacaactt agttacgtca aaatcgcaaa ccgaaacacc
      661 gtctattaac tcttttgagt aggcatagta gccaccgata gcattgattt cacggcgggc
      721 atactcagat agctcaatga ctttctcaaa cgactcttta ccacgaaggg ccaagttgcg
      781 acgtgaaata tccaaactag ccatcaacaa gtaagaggca gatgtagact gggtcaggtt
      841 aattatctga cgaacgtatt cagaattcat ctgctccccg ataagtaaaa tggagctttg
      901 ggtcaaactc ccaccagact tatgcatgga aactgctgcc atatcagccc ctgcatccat
      961 agcagaaatt ggaagtttat cagtgaaatg caaatgcgct ccgtgggctt catctactaa
     1021 aaccatcatg ccagcttcat gagccatttc tgtcaacccc tttaggtctg aacagatgcc
     1081 gtagtaagta ggattgttga ttaggatagc cttagcatct ggatggtcct ttatggcctg
     1141 tgctactcgg tcattttcaa gacctaaagc gataccaatc ttaggatcta cactcatctc
     1201 gatatagatg ggaatagcac cacatagaac caacgcattg atagcagatt tatggacatt
     1261 tcgtggcaga ataatcttat ctcctgcctt gcaggttgcc agaatcatag tctgcaccga
     1321 tgaagttgtt ccaccaatca ttagaaaggc atggctagct ccaaaagcat ctgcagccag
     1381 ctcctctgca tcacgaataa tcgaaatagg atggcctaaa ttatccaagg gtttcatcga
     1441 attgacatca atgcctacac atttttctcc taagagttcg acaagttctg gatttccccg
     1501 tccacgcttg tgacctggaa catcaaaggg aacaatcctt ttcttgcgta acttcaccaa
     1561 ggcctcataa attggggctt ggttttgatc taactctttc aaaacatact cctttcaata
     1621 tttttaggac cttatgaaaa ctaaggaact aaaggttgac tcatgaaaaa agagcaggtt
     1681 ttcacctgct ctgcaatctt ctgacgtgtt tattttggtt tctgttgagt atgtctgttc
     1741 ccgatgtttc ctaactctct agtagcaaat attacgtact ttattgatcg tttcacaaga
     1801 tgacgtgtgc tttcaccaca ctaaaaattt atgaattagg acaagtgtcc taacatcaac
     1861 ttataaaagt aggcttttaa ccctatcaat aatgtggctt ttcaaccacg cttcggcatt
     1921 caaccctgcc tgtccgtagg cattttttac tcgggtttat atttgctaga aaacatcatc
     1981 tcattttcta agctttatta ctatatcatg tttttaagaa cttgtaaagt attttttgat
     2041 aaaaaacaaa aatatagtag attgaaacta gaatagtaca cttctgcttc taaaacatta
     2101 ttagaaatag attttactgt cctgatcgat ttgttctgtt cttgtttcat tttactatat
     2161 gttcgtaaat gaaagttcta taatgaagtt agccacccag ccctcctaaa aattagatgg
     2221 ttcaactagc tgatagctct tgtaggcata agaaaacacc tctgtgttat acttgttgtt
     2281 caaccacaaa cacaagaaag gcacagagat gcaagacaat tatactacaa aagccaaaca
     2341 tttgacaatc gatagccgtc gcttaatcga aagatggaaa aaagaaggga aatcaaatag
     2401 agaaattgcc tctctgcttg gaaaagttcc tcaaactatc cacactgaaa tcaagcgtgg
     2461 gacagtccga caatgtcttg gaaaagggcg cttcaaagag gtttattctg ccgactatgc
     2521 tcaacagtct tatgaaaaca atcgcaagcg ctcggtcagg aaatcaagcg tgaccaagga
     2581 actaaaggaa aagattctcc actatcataa ccaaaaattt tcgcctgaaa tgatggtgat
     2641 ggttaaaggg gttaacgtgg gaatttcaac catttactat tggattcatc atggaaaatt
     2701 ggggttaagc aaacaggatc tgctttaccc tagaaaagga aaagcgctta agaaacaggc
     2761 tagcaccaac tttaaacctg ctggtcaatc catcgaacag cggtctgaag ctatcaatct
     2821 tcgcttggag aatgggcatt atgagattga tacggttcta cttacgagag cgaaaaacta
     2881 ctgtttgctt gtcttgactg atcgaaagag tagacatcag atcatccgat tgattccaaa
     2941 taaaagtgct gatgtggtca atcaggctct aaaactcatc ttaaaacaac acaagattct
     3001 ttccatcacg gcagataatg gaacggaatt caatcgcttg tttgatg
//
LOCUS       DBEJZV010000078         2916 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.78, whole genome shotgun sequence.
ACCESSION   DBEJZV010000078 DBEJZV010000000
VERSION     DBEJZV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2916
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.78"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..550
                     /locus_tag="ACL3S0_002125"
                     /pseudo
     CDS             1..550
                     /locus_tag="ACL3S0_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            625..1020
                     /locus_tag="ACL3S0_002126"
                     /pseudo
     CDS             625..1020
                     /locus_tag="ACL3S0_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621054.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(1232..1624)
                     /gene="rpsI"
                     /locus_tag="ACL3S0_002127"
     CDS             complement(1232..1624)
                     /gene="rpsI"
                     /locus_tag="ACL3S0_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGR1312959.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(1643..2089)
                     /gene="rplM"
                     /locus_tag="ACL3S0_002128"
     CDS             complement(1643..2089)
                     /gene="rplM"
                     /locus_tag="ACL3S0_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGR1312960.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            2446..2763
                     /locus_tag="ACL3S0_002129"
     CDS             2446..2763
                     /locus_tag="ACL3S0_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGR1312961.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
BASE COUNT          913 a          569 c          538 g          896 t
ORIGIN      
        1 tcttctcata aaggagacgt tggtaagaaa gcagagaatc tcattcaagg ccaatttgaa
       61 ggctctaaaa caatggaaaa gtgctacaca gatgtgacag aatttgccat tccagccagt
      121 actcaaaagc tttacttatc accagtttta gatggcttta acagtgaaat tatcgcctat
      181 aatctttcaa cttcacccaa cttagaacaa gtacaaacaa tgttggaaca ggcattcaaa
      241 gagaagcact atgagaatac gattctccat agtgaccaag gctggcaata ccaacacgat
      301 tcttatcatc ggttcctaga gagtaaggga attcaagcat ccatgtcacg taagggcaac
      361 agcccagaca acggtatgat ggagtccttc tttgggattc tgaaatcgga aatgttttaa
      421 gtcgtttcag tcgcttaagc aattggaaca agctattgta gactatattg attactacaa
      481 caataagaaa attaagataa aactaaaagg acttagtcct gtgcaataca gaactaaatc
      541 cttcggataa attaattgtc taactttttg ggggcagtac ataagaacct tggtaatatg
      601 cgttttatta tggcaacatt tcccattttc tctatttcta atgacttact tcaactcctt
      661 acctcttgga aagaacaaca aagatatgaa ctagcaaagt ttggcatcct cagtaatcca
      721 gaacaatttg tttttacata tatcgacaca aaaggaaaca tcaacaagcc tttacatgcc
      781 gactatctga acaataaaat gaaaagcatt agaaagcgac ataaagaact gacacacgct
      841 acacctcaca aattacgcca tacaggcgca actctagcta aataagcagg aatgagctta
      901 gaagccattt ctgaagcact aacgcatagc gatacaggca caactcaaat ttatgtcaac
      961 acctctaatg tagttcctat gacagtaggt gaatttgctt taaagtctct aaaacaataa
     1021 ggtatagtag attgaaacta gaatagtaca cctctacttc taaaacattg ttagaattcg
     1081 atttgactgt cctgatcgat ttgtcctatt cttatttcat ttcgctataa aaataaggta
     1141 aactttgaga taaacttttc aaaaaaacac gaaaaaagca cccataaggt aaacttttga
     1201 gtgctttgaa acgttgatat aatcgtattg attaacgttt actaaattgt gatgctttac
     1261 gagctttctt aagacctggt ttcttacgtt caactttacg tgagtcacgt gtaagaagtc
     1321 ctgcgcgttt caatgaatcg cggaagtctg ggtctacttg aagaagggca cgagcgatac
     1381 cgtgacggat agctcctgat tgaccagcgt atccaccacc tacaacgtta acgaaaacgt
     1441 cgtatgaacc tacagttgaa gtaactgcga atggttggtt gatgacaaga cgaaggtcag
     1501 cgtgtgggat gtactcttca acatcttttt tgttaacagt gattttacca gttcctggaa
     1561 caaggcgaac gcgtgcaaca gcgtttttac gacgtccagt acctgcatat tgtgcttgtg
     1621 acatacttta ttgttccttt ccttagataa gtcctgaaat gtcaagaact tctggttgtt
     1681 gtgcagcgtg agtgtgctca gctccaacaa atactttcaa cttcatacct tgagcgcgtc
     1741 caagtgtatt gtgtggaagc atacctttaa ctgatttctc aatcaaacgt actgcatttt
     1801 tagaacgaag ttcacctgca gagatttgtt tcaatccacc tgggtggttt gagtgagtgt
     1861 agtagatttt atcagttgct tttttaccag tcaatttaac tttttcagca ttgataacaa
     1921 tcacgaagtc acctgtatca gtgtgtggtg taaatgttgg tttgtttttt ccgcgaagta
     1981 cgctagcaac tactgcagaa agacgtccaa gtggtacatc agttgcgtca actacgtacc
     2041 atttacgttc aacttggcct ggtttagcca taaatgttgt tttgttcatg atttctccta
     2101 tatatagttc gatttttgtt tacggtgatg ggtgttcctt cccatcgaaa agtatttgga
     2161 aggttccggg gcctttcaaa tggggtaaac aataccgcct actatcatac caaatttcac
     2221 ccctaaaagt caatagatat gaaaaatatt tttcggtaac ttctcaaagt aactgaaagt
     2281 tatataatca agttaatttg ggaatttacc tattaacttc ggtagatttt tgagaatttt
     2341 tttccttctt tttccttgta gttaaaatcc ttttcaaaaa atcacctttt cttgattttt
     2401 aatcctattt gctgtatgat aagggaaaag aaaggggaca gagatatggc ttttaccaat
     2461 acccacatgc gatctgctag ttttggcatt gttaccagct tgcctgatga catcattgac
     2521 tctttttggt atattatcga ccatttctta aaaaatgtct ttgaattgga agaagaactc
     2581 gagtttcaat tgcttaataa ccaaggaaag attaccttcc acttttcaag tcaacacctc
     2641 cctacagcca ttgattttga ctttaaccat cctttcgacc ctcgttatcc cccaagagta
     2701 ctggttttag acatggacgg tagagaaact atcctcctcc cagaagaaaa tgacctattt
     2761 taatacttaa tgaaaatcaa agagcaaact aggaagctag ccgcaagctg tacttgagta
     2821 cggtaaggcg acgctgacgt ggtttgaaga gattttcgaa gagtataaaa actctagcct
     2881 tcagttgcaa gtaactgaaa actagagttt ttctat
//
LOCUS       DBEJZV010000079         1951 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.79, whole genome shotgun sequence.
ACCESSION   DBEJZV010000079 DBEJZV010000000
VERSION     DBEJZV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1951
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.79"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..1409)
                     /gene="pcpA"
                     /locus_tag="ACL3S0_002130"
     CDS             complement(<1..1409)
                     /gene="pcpA"
                     /locus_tag="ACL3S0_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGR1312962.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNDGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKG"
     gene            1744..1950
                     /locus_tag="ACL3S0_002131"
     CDS             1744..1950
                     /locus_tag="ACL3S0_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1312963.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KKTLTPTKESIDFLRNKIMKQVNN"
BASE COUNT          661 a          311 c          268 g          711 t
ORIGIN      
        1 cctttgtctt taacccaacc aactactccc tgattagaat tctttttagg tttagctaca
       61 tcagtttctt gttttatatt atctactttt tcaacaatga tatcattact agtagataaa
      121 tttgatttaa gaacatcttt tatatgttct gatgttacat agaacttaac agtttcagga
      181 attgcaaatg tatctttttt cacagaaaac tctgtacttt tattcttaat atgaatttcc
      241 tttaatgaat ctaagacgcc acttaggaag aaggacggca atgagttgat attattacca
      301 attgttaaac tttttaattt tggtaaaccg ttcataacgt gtttaccaaa atttttaaca
      361 ttatctggta atataagttc ttttaattct aaattaccgt aaaaggctaa acgttcaata
      421 gtttctaaac tatttggtaa gctaatttct tcaagtttaa tcgcatctgc aaatgcaaaa
      481 gtaccgattt tttctaaacc atcattcaat tcgagttttt tcaagtaaga atttttatta
      541 aacgaatatg atgcaagttc ttttgtctcc ttaggcgttt tataactttc gtcatttttt
      601 tgacttggat aataaattaa ttgagtttta tcttttgaaa acaaaacacc atcaactgag
      661 gcaaacgatt catttccttc ttcaacatca acatgtttta agctagtagt gagtctaaat
      721 agattacttc ctaatgtttt aaccgatttt ggtaatgtta gtttctctaa atttgataaa
      781 ttagcaaaag cctcatgtga tattaattct aattttgaac ttgaggaaaa ggttagcttt
      841 ttcaattttt gactaaaaga aaatgcactt gttccaatat attctagaga tgcaggcaat
      901 tcaatctctt ctaattcaga aaaatcaaaa gctctatctt caattttctc cagctgactg
      961 cctttgtcaa aaataatagt tttagcttta cttccatgga agcctttttt ttgtattttt
     1021 tttatgcttg atgggatagt aatagagcta ggatagtaga caattctacc tgtttcatct
     1081 ggataataac taaaagcttg actagctact tcagtaacgg taaatacttt atcacctact
     1141 gtgatttttg taggaatcgt gaatggtttt ccatcttgac cagcttcaaa ctctacagga
     1201 gtaactccat tacccacttg aacagttcct atgttacctt ctacagttag aaccttatat
     1261 ttgatattat tttgttgaat aatacttcca actttagtct ctttgattac ttccgaacta
     1321 ggagtatctg ctaggattgg ttcattaggg acatatgctg ctaaaataac cgcagctgta
     1381 gttaatgata atattgtagt ttttttcatt taaatttcct tacatattta ttttctaata
     1441 gatataaaat tataactttg ctagccgttg ttataaaaag ttttattcaa tcattatcta
     1501 gtagaataga gtagtacatt ttataaattg tcatctctct ataaacacag tatatcattt
     1561 ttaaatttta agtcaaggaa aattaaccca ctttaatttc ttttttaacc cgggttaaaa
     1621 aagaaattaa agtgggttaa aaaagaaatt aactgagtaa aaactctcga aattcaatta
     1681 gctatattat cactcaactt gaacaaatac cagaaccaca aaaaacagat gtaaaggaaa
     1741 aatatggact taaaatttga aggggttgat ttagaataca aaaaagctaa aaacaatctt
     1801 ccagagtctt tctgggaaac ctactcagca tttgcaaata caaatggcgg gaaaataatt
     1861 ctcgggatag atgaaaaaaa aacattgacc cctaccaagg agtcaataga cttcctgcga
     1921 aacaaaatta tgaagcaagt aaacaactaa c
//
LOCUS       DBEJZV010000080         1484 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.80, whole genome shotgun sequence.
ACCESSION   DBEJZV010000080 DBEJZV010000000
VERSION     DBEJZV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.80"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            40..476
                     /locus_tag="ACL3S0_002132"
                     /pseudo
     CDS             40..476
                     /locus_tag="ACL3S0_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            641..940
                     /locus_tag="ACL3S0_002133"
     CDS             641..940
                     /locus_tag="ACL3S0_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGR1312964.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1201..1437
                     /gene="tnpB"
                     /locus_tag="ACL3S0_002134"
     CDS             1201..1437
                     /gene="tnpB"
                     /locus_tag="ACL3S0_002134"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR1312965.1"
                     /translation="MMIRLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGKLT"
BASE COUNT          513 a          293 c          265 g          413 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaagcg aatacagact atattgctcg ctatggcgta tatgcagtta tccctaatcc
      121 tgaacaaaaa caaattgttc ttgttcaaga accaaatggt gcttggttcc taccatgtgg
      181 agaaattgaa gcaggtgaaa atcatcagga agccctaaag cgtgagttga ttgaagagct
      241 tggtttcaca gcagaaattg gtacctatta cggacaagct gacgaatatt tctattctcg
      301 tcatcgtgat acctactact ccaatcctgc ctacctctat gaagcaactc ctaaagccac
      361 tagaaaactt taatcatatt gcctggttcc ctattgacga ggctatcaaa aaccttaaac
      421 gtggtagcca taaatgggcc attgaatctt ggaaaaaaca gcataagatt gactaatact
      481 cttcgaaaat aaaattcaaa ccacgtcagc gtcgccttac cgtactcaag tatagcctgc
      541 ggctagcttc ctagtttgct cttttatttt cattgagtat aaatcaagcg actttattca
      601 aaaagtgcta taatagaatt agaaaatcgg aggaaatatt atgaagctta tcaatacgac
      661 aaactcacac tcgcaacttg taaaaagtca gctagaaagt accgatgcaa cccttgttga
      721 ggtttattct gcagggaata cagatgttat ttttacccaa gctccgcttc actatgaaat
      781 cctcatctca aacaaacacc gtgctattcg tgagcctgaa atcgaaacca ttcaagaatt
      841 tttcttgaaa cgtaaaattg ataagacctc tgttgatgaa gccaatatca agacactcta
      901 ctcagagaaa ttaattggaa tttcaatccc aatcaagtaa gaaaattgag taaaaactcg
      961 atttgagaga aagtccaata agtctttcca taacaaaacg catagtaaca agagtttcta
     1021 cacccactat tatacgtttt tatcattttg aaatctgctg ctaatcaatg aagaagcaaa
     1081 gatcaaacta ggcagctagt tacaagttac gtaagcgcgt cataacaagg tatctatcct
     1141 aattccccaa cttccagtat actagataaa aaataattat cagaggaaaa gtattgtact
     1201 atgatgattc gactaagtga tttaggtcaa gttcaccttg tttgtggcaa gacagatatg
     1261 aggcagggaa tagactcatt agcctatgta gttaaaaccc actttgaatt ggatcctttc
     1321 tcaggtcaag tttttctctt ttgtggtgga cgtaaagacc gctttaaagc cctttactgg
     1381 gatggtcaag gattttggct actatataaa cgctttgaga acggaaaact gacttgacca
     1441 agtacagaaa aggatgtcaa agctctcgca cctgaacaag taga
//
LOCUS       DBEJZV010000081         1448 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.81, whole genome shotgun sequence.
ACCESSION   DBEJZV010000081 DBEJZV010000000
VERSION     DBEJZV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1448
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.81"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            103..1299
                     /locus_tag="ACL3S0_002135"
                     /pseudo
     CDS             103..1299
                     /locus_tag="ACL3S0_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
BASE COUNT          481 a          213 c          283 g          471 t
ORIGIN      
        1 tttctaagtt catagatctg aactttatca tcataagtta atttcataat aaaaacaccc
       61 caaaagttag attttttctg tctaactttt ggggtcagta cactttggct tttaaaccat
      121 tatcactatc aagatagttg taaaaatgca gaaggtggtt tgattttatc aagatatgca
      181 ggtcctggta gtcaccgcta ccctgttggt ttttcagggg atactattat tagttggaat
      241 tccttaagat ttcaacccta ttttacagcg acagcatcta atatcggtta tagttggtgg
      301 agtcatgata tcggtggaca tatgttgggg gattatgacg aagagctaca aactagatgg
      361 ctacagtttg gtgtttttag tccgattact cgattacata gttctagaag tccttttaat
      421 agtaaagaac cttggttctt ttcagaaaca acatctaaga ttatgaagaa ataccttcgt
      481 ttgagacatc agatgattcc ctatctatat accatgaatg taaagacaca tgaggaaggt
      541 gccccattaa tcagtccaat ctattatttc tatccagaga ataatgagag ctataatgtt
      601 ccaaaccaat acttttttgg aacagaactg atggtggctc ccattgtaga aaagatggat
      661 ttgacattcc aatctgcaaa agtagatgta tggttccctg aaggtgaatg gtatgacttc
      721 ttttcagaga aaaaatacac aggtggtgtg aagttaagtg tttataggga catctcgact
      781 acgcctgtgt ttgcaaaaag tggtgcaatc attcccttgg ttggttctga gataggtatg
      841 ggtgttgatt tacctgaagt tgtagattgg tatgtattcc cagggaaaca acattctttt
      901 gaaatgcttg aagatcaaaa tggtcaaaga tataaaacaa gattatcaat cgattgggaa
      961 atgggaatgg tagagttagc attacaagga gattctagta tcgttccaag caatagaaaa
     1021 catagaattc attttaaagg aacgaatgtg tctataattg aattgccaaa taagaatgat
     1081 acagctaaat ttgaatggaa agataataaa aggacatctt taaatgacga agtttttaga
     1141 ctactaaaga cagcttctct tccatatgaa ttaaaagata gattgttaaa tcaattcatc
     1201 aatgcgaaaa actctcatga cttaatgaat atcttgcatc atcaggataa ggaattgaga
     1261 gggagtttgt tggaaatgat atttactagc caaaactaat tgaaataatt agaaagtcat
     1321 ttgtttagtg tatatgaaga ttctgtatgg tattcgttat cactggtcac attgaaaatg
     1381 tgaaataagc acctacaaca tagactttac aacacttcat gtttcatatc atggggtgtt
     1441 tttctatt
//
LOCUS       DBEJZV010000082         1014 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.82, whole genome shotgun sequence.
ACCESSION   DBEJZV010000082 DBEJZV010000000
VERSION     DBEJZV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.82"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..107)
                     /locus_tag="ACL3S0_002136"
                     /pseudo
     CDS             complement(1..107)
                     /locus_tag="ACL3S0_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(195..716)
                     /locus_tag="ACL3S0_002137"
                     /pseudo
     CDS             complement(195..716)
                     /locus_tag="ACL3S0_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(736..831)
                     /locus_tag="ACL3S0_002138"
                     /pseudo
     CDS             complement(736..831)
                     /locus_tag="ACL3S0_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608003.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          282 a          224 c          194 g          314 t
ORIGIN      
        1 gcttgcttgg ggggcacttc aaaaaacttc cttctcacat gcgcccaaca tccaacaagt
       61 gcagcttctt ccagttgacg ataagcttct agctgttcgc agtttaccaa gcttagcgtc
      121 gccttactcc taaactttgg actgctatcg cataggcaga actagaggac taaagtccta
      181 agttactgcc gcaacatgtc acaatgaaca tagccagaat aatctcctag gaattcttgt
      241 actactaaac cactccgacg ctgatcatgg tggtacagcg tgattgcttg attctcagct
      301 ttcccagaca aaaaagtcca atagtaagtc aactgactat cactctctag aacccgataa
      361 gaggtttcat ccgcatgaag taagggcttg agtcaatagt ctcgttataa aggggcttta
      421 ggaataggag ctttcacgat tttatcactc ggatttttat cactgcatgc ttggcatttg
      481 taagcgtgtt ggatatgatc tatgcgtttt aattgcgcag gaataaagac caattcttgt
      541 ccttgaagac tccctccaat ctcttttaga tctccctgac aatcagggca aatcctctct
      601 tctacttgat gatgaacttc ttctgaatca aattgggcaa gaagagcttg gcgtttccct
      661 ttagatttct tacgtttgta ggtaatttcc tctgtttcaa ctgggaacat ctccatcttc
      721 ctcagatgga gactcttcct caaaaaggtt gagttgtcca gaggggcaaa cacttttctc
      781 agaggatttt ccatagagct tttgagtcag ataagccact tgttcacgaa gaagggcaag
      841 ttcattggtg agactatcaa ttgtagcact ctgttgttga atgattttca atcttcttcc
      901 atgagcttcc ctctctgttt tctaacttta ttatactaaa aagaaagtcc tcatttcaat
      961 agaaatcacg actttctgat ggatttatag taaaatgaaa taagaacagg acaa
//
LOCUS       DBEJZV010000083         1006 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.83, whole genome shotgun sequence.
ACCESSION   DBEJZV010000083 DBEJZV010000000
VERSION     DBEJZV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.83"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..217
                     /locus_tag="ACL3S0_002139"
                     /pseudo
     CDS             1..217
                     /locus_tag="ACL3S0_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
     gene            320..1006
                     /locus_tag="ACL3S0_002140"
                     /pseudo
     CDS             320..1006
                     /locus_tag="ACL3S0_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          344 a          170 c          194 g          298 t
ORIGIN      
        1 aactaaagaa gaaatccaaa ccatcaaaac acttttaaaa gactctcgta cagctaaata
       61 ttataaacgc cttcaaatcg ttctatagta aaatgaaaca agaacaggac aaatcgattt
      121 ctaacaatgt tttagaagta gaggtgtact attctagttt caatctatta tatttcgcct
      181 gatgggcaaa tcttataaag agattataga acttttatag tggtttgaaa taagatgtga
      241 acaactctat caggaaagtc aaattaattt atagaaatat tttagcagcc aaggtgtact
      301 gtcatagatt caatacacta tagactgtaa tcaaacaacg atttggcgaa atgtaaaaaa
      361 atatgaggag ttcggactcg actctctcct tcaagaaaca cgtggtggtc gtaaccatca
      421 tatatgacag ttgaggaaga aaaagccttt cttgcccgcc atttgaaggc tgcagaggca
      481 ggagaatttg ttacaattga tgccttattt caggcttata aaaaggagtt aggtcgttcc
      541 tacacacgtg atgccttcta tcaactgttg aagcgccatg attggcgaaa tattatgcca
      601 cgtccagaac atcctaagaa agcagacgct caaaccattg tcgtgtctaa aaataaaatc
      661 tcaattaaag aagacaagaa agcgctttaa aaccagtaga cgttttcgta aggttcgctt
      721 gatgtaccaa gatgaagctg gtttcggtag aatcagtaaa ctgggatctt gttggtctca
      781 aataggagta ggtccacatg ttcatagtca ctatatacga gaatttcgct attgttatgg
      841 agctgttgat gcctatacag gcgaatcatt tttcttaaga gctggtggat gtaatactga
      901 gtggatgaac gtctttttag aagagctttc acaagcttat ccatatgatt attttttact
      961 cgttatggac aatgctatat ggcataaatc aagtacctta aagatt
//
LOCUS       DBEJZV010000084          909 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.84, whole genome shotgun sequence.
ACCESSION   DBEJZV010000084 DBEJZV010000000
VERSION     DBEJZV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.84"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..327)
                     /locus_tag="ACL3S0_002141"
                     /pseudo
     CDS             complement(1..327)
                     /locus_tag="ACL3S0_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(434..871)
                     /locus_tag="ACL3S0_002142"
                     /pseudo
     CDS             complement(434..871)
                     /locus_tag="ACL3S0_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
BASE COUNT          259 a          206 c          186 g          258 t
ORIGIN      
        1 aaaatggtct taaaggtttc ttcatacttg aggctgtatt caattgccct tcctagtttt
       61 gaacccgata aaactgactg acgacggcac caagcaaaga agtcttccag taggggttgg
      121 agatgttctt gacgtttctg tagtcgttca tcagctggca aagcctccca gtctctttcc
      181 aaggaaaata actgatcaca ataagctaaa cctttagctc ctaaggatga tttatccgct
      241 tgcttggggg ggcgcttcaa aaaacttcct tctcacatgc gcccaacatc caacaagttc
      301 agcttcttcc agttgacgat aagcagacga gcggttcgaa gtttaccaag cttagcgtcg
      361 ccttgctcct aaaccttgga ctgctatcgc ataggcagaa ctagaggact aaagtcctaa
      421 gttactgccg caaaatatca caatgcacat agccagaata atctcctagg aattcttgta
      481 ctactgaacc acttcgacac tgatcatggt ggtaaagcgt aatcccttgt ttctctgctt
      541 tacctgacaa aaaagtccaa tagtaagtca gctgactatc actctctagc accctataag
      601 aagtttcatc cgcatgaagt aagggctgag tcaatagtct ctctcgcaag aggttataaa
      661 ggggctccaa atagtattga ctcgccttga tatgccaatt agagatttcc ttacgtgtga
      721 ttggtaaacc catcctagcc caatcttctt cttggcgata attgggtacc ttcagattaa
      781 acttctgatg gatggtgtga gcgataatag aagctgagcc aaagttatgc gctaaagggg
      841 ctttaggaat aggagatttc acaagcttat ccagatgatt atcttttact cgttatggac
      901 aatgctata
//
LOCUS       DBEJZV010000085          906 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.85, whole genome shotgun sequence.
ACCESSION   DBEJZV010000085 DBEJZV010000000
VERSION     DBEJZV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.85"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..>906
                     /locus_tag="ACL3S0_002143"
     CDS             <1..>906
                     /locus_tag="ACL3S0_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGR1312966.1"
                     /translation="KLKERISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYAC
                     KELSADAYFPKLLEGGQLASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQ
                     LIVDIDSTHFTTYGKQEGVAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEE
                     ADSFITPVLERFNQLLFRMDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLP
                     CPQDEDLTILPHSAYSETLYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTS
                     QDQFQLYRGRGQAENFIKEMKEGFF"
BASE COUNT          250 a          207 c          181 g          268 t
ORIGIN      
        1 tgaaactaaa agagcggatt tctaagtatt tagtaacgaa tgaccaacgc cgctactgtc
       61 gttattcgga ttcagatatc cttgtccagt tcctctttca actgttaaca ggttatggaa
      121 cggactatgc ttgtaaagaa ttgtcagctg atgcctactt tccaaaatta ttggaaggag
      181 ggcagcttgc ttcacagcca accttatccc gttttctttc cagaactgac gaggaaacag
      241 tccatagttt gcgatgcctc aaccttgaat tggtcgaatt ctttttacag tttcaccagc
      301 taaaccaact cattgtagat atcgattcta cccatttcac aacttatggc aagcaagaag
      361 gtgttgctta taacgcccac tatcgtgctc atggctatca tcctctttat gctttcgagg
      421 ggaagacagg ttattgtttc aatgcccagc ttcgtcctgg taatcgttat tgttctgaag
      481 aggcagacag ctttatcaca cctgttttag aacggtttaa tcaacttctc tttcgaatgg
      541 atagtggctt tgcgacccca aaattatacg atttaattga aaaaacaggg caatactacc
      601 tcataaaact caagaaaaat actgttctga gccgtcttgg agacctttcc ctcccttgcc
      661 cacaggatga ggacttaacc atcttgcccc actccgccta ctcagaaact ctctatcaag
      721 caggatcttg gtcgcacaag cgtcgtgtct gccagttctc tgaacgaaaa gaaggaaact
      781 tgttctacga tgttatttct ctcgttacaa atatgacgag tggaacaagc caagaccagt
      841 ttcagcttta tcgtggacgt ggtcaagccg agaatttcat caaggagatg aaggagggat
      901 tttttg
//
LOCUS       DBEJZV010000086          829 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.86, whole genome shotgun sequence.
ACCESSION   DBEJZV010000086 DBEJZV010000000
VERSION     DBEJZV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..829
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.86"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..>829
                     /locus_tag="ACL3S0_002144"
     CDS             <1..>829
                     /locus_tag="ACL3S0_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HGR1312967.1"
                     /translation="CSKMMVAETPLVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLA
                     ISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDNLNIITVLEGRT
                     QAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDRFHIIQHLSRAM
                     SRFRVQIMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKI
                     LSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEK"
BASE COUNT          263 a          171 c          135 g          260 t
ORIGIN      
        1 actgttcaaa aatgatggtt gctgagactc ccctggtaaa gaaaaatcac caaatccctc
       61 gtatcatcaa ccaaaaaatt gctcaaaagt taattgaaaa aatttctatg actgatattg
      121 cccatcagct ggccatttca acttcaactg tcattcgcaa gctcaatgac tttcactttg
      181 agcatgattt ttctcggctt ccaaagatta tgtcttggga tgagtatgcc ttcactaagg
      241 gaaagatgag tttcattgcg caagattttg ataatcttaa tattatcact gttcttgaag
      301 gcagaacaca agctgtcatc cgaaatcact ttcttcgcta cgatagagcc gttcgttgtc
      361 aagtgaaaat cattacgatg gatatgttta gtccttacta tgacttggct aaacagcttt
      421 ttccgtgtgc taaaatcgtt ctagatcgtt tccatattat ccaacatctc agccgtgcca
      481 tgagtcgttt tcgtgttcaa attatgaatc agtttgaacg aaaatctcat gaatacaagg
      541 ctatcaagcg ttactggaaa ctcatccaac aggatagtcg taaattgagc gataaacgtt
      601 tttatcgccc tacttttcgc atgcacttaa caaataaaga aattcttgac aagattttaa
      661 gctattcaga agacttgaaa caccactatc agatctatca actcttactt tttcactttc
      721 agaacaaaga ccctgagaaa tttttcggac tcattgagga caatctgaag caggttcatc
      781 ctatttttca gactgtcttt aaaacctttc taaagaacaa agagaaaat
//
LOCUS       DBEJZV010000087          692 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.87, whole genome shotgun sequence.
ACCESSION   DBEJZV010000087 DBEJZV010000000
VERSION     DBEJZV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.87"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(74..147)
                     /locus_tag="ACL3S0_002145"
     tRNA            complement(74..147)
                     /locus_tag="ACL3S0_002145"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="ACL3S0_002146"
     tRNA            complement(157..242)
                     /locus_tag="ACL3S0_002146"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="ACL3S0_002147"
     tRNA            complement(250..321)
                     /locus_tag="ACL3S0_002147"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="ACL3S0_002148"
     tRNA            complement(344..416)
                     /locus_tag="ACL3S0_002148"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="ACL3S0_002149"
     tRNA            complement(435..516)
                     /locus_tag="ACL3S0_002149"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="ACL3S0_002150"
     tRNA            complement(522..594)
                     /locus_tag="ACL3S0_002150"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="ACL3S0_002151"
     tRNA            complement(619..691)
                     /locus_tag="ACL3S0_002151"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DBEJZV010000088          687 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.88, whole genome shotgun sequence.
ACCESSION   DBEJZV010000088 DBEJZV010000000
VERSION     DBEJZV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..687
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.88"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..687
                     /locus_tag="ACL3S0_002152"
                     /pseudo
     CDS             1..687
                     /locus_tag="ACL3S0_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          200 a          149 c          129 g          209 t
ORIGIN      
        1 tctaagatcc cttacctcga aacaactggt atgcctacta gaattctcct tagaaaacgc
       61 cgtttcaagt gctatcactg ttcaaaaatg atggtcgctg aaacttctat cgtcaagaag
      121 aatcatcaaa ttcctcgtat tatcaaccaa aaaattgcgc aaaagttgat tgagaagatt
      181 tctatgaccg atattgctca tcagctggcc atttcaactt caactgtcat tcgcaagctc
      241 aatgattctc actttgagca tgatttttcg cgtcttcctg agattatgtc ctgggacgtt
      301 gaaacagtcc ggggagtgac tgtttcaatc gggagatgga gatgagcttt attgcgcaag
      361 attttaacaa tctcaatatc atcactgttc ttgaaggtag aacacaagct gtcatccgag
      421 atcactttct taaatatgat agagccgtcc gatgtcgcgt caaaatcatt actatggata
      481 tgtttagtcc ttactatgac ttagctagac aacttttccc gtgtgctaaa atcgttcttg
      541 atcgctttca cattgtacaa catcttagcc gtgctatgag tcgtgtgcgt gttcaaatca
      601 tgaatcagtt tcatcgaaaa tcccatgaat acaaggctat caagcgctac tggaaactca
      661 ttcaacagga tagccgtaaa ctgagtg
//
LOCUS       DBEJZV010000089          659 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.89, whole genome shotgun sequence.
ACCESSION   DBEJZV010000089 DBEJZV010000000
VERSION     DBEJZV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.89"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..366)
                     /locus_tag="ACL3S0_002153"
     CDS             complement(<1..366)
                     /locus_tag="ACL3S0_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGR1312968.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAAVFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINR"
     gene            complement(459..>659)
                     /locus_tag="ACL3S0_002154"
     CDS             complement(459..>659)
                     /locus_tag="ACL3S0_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HGR1312969.1"
                     /translation="FSQSFEGAKARAIIMSLLETAKRHQLNSEKYLSYLLECLPNEET
                     LVNKEVLEAYLPWTKVVQEKCK"
BASE COUNT          188 a          132 c          114 g          225 t
ORIGIN      
        1 gcgattgatt tttacttccg tcgcatcaat cattaccgtg tcctcagaac tgagaggagt
       61 tcttgaaatc gtaacaccac tttgaacaag agttacttca acccattggc tccgacggat
      121 taagttgctt tcgtgaatac caaaaacagc cgcaatttgt tcataagttc gatattctcg
      181 cacatattga agagtggcca taagaaggtc ttctagactt aatttaggtt ttcgtccacc
      241 ttttgcgtgt ttaagttgat aagctgtttt taatacagct aacatctctt caaaagtcgt
      301 gcgttgaaca ccaacaagac gcttaaatcg tgcatcggtt agttgtttac ttgcttcatc
      361 attcatagaa ctattatacc atattttgtt tcgcaggaag tctattgaaa aatctccaga
      421 ctggagaact cacggatagt tcctaatctg gagatttctt atttgcactt ttcttgtaca
      481 actttagtcc atggtaaata agcctctaaa acctctttgt ttacgagagt ttcctcgttt
      541 ggaagacatt ctagaagata ggatagatat ttctcgctat ttaattgatg acgtttagct
      601 gtttccaaca aactcataat aatagctctt gctttagctc cttcaaaact ttgagaaaa
//
LOCUS       DBEJZV010000090          488 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.90, whole genome shotgun sequence.
ACCESSION   DBEJZV010000090 DBEJZV010000000
VERSION     DBEJZV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.90"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..439
                     /locus_tag="ACL3S0_002155"
                     /pseudo
     CDS             1..439
                     /locus_tag="ACL3S0_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          168 a           79 c           92 g          149 t
ORIGIN      
        1 tattcttctc ataaaggaga cgttggtaag aaggcagaga atctcattca aggccaattt
       61 gaaggctcta aaacaatgga aaagtgctac acagatgtga ctgaatttgc cattccagca
      121 agtactcaaa agctttactt atcaccagtt ttagatggct ttaacagcga aattattgct
      181 tttaatcttt cttgttcgtc taatttagaa caagtacaaa caatgttgga acaggcattc
      241 acagagaagc actatggtgg agtccttctt tgggattctg aaatcggaaa tgttttatgg
      301 ctatgagaaa acatttaaat cacttaatca attggaacaa gctattatag actatattga
      361 ttattacaac aacaagagaa ttaaggtaaa actaaaagga cttagccctg tgcaatacag
      421 aactaaatcc ttcggataaa ttaattgtct aactgtttgg ggtgcagtac agaactggcg
      481 ttttattt
//
LOCUS       DBEJZV010000091          413 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.91, whole genome shotgun sequence.
ACCESSION   DBEJZV010000091 DBEJZV010000000
VERSION     DBEJZV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.91"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..243
                     /locus_tag="ACL3S0_002156"
     CDS             <1..243
                     /locus_tag="ACL3S0_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HGR1312970.1"
                     /translation="FLKHLAGGDFQTLTIKRFRHLFLHVVGKCVRTGRKQLLKLSSLY
                     AYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT          130 a           82 c           91 g          110 t
ORIGIN      
        1 tttctcaaac atctagctgg aggtgacttc caaactttaa caatcaaacg cttccgccat
       61 ctttttcttc acgtggtagg aaaatgtgtt cgaacaggac gcaagcagct cctcaaattg
      121 tctagtctct atgcctattc cgaattgttt tcagcacttt attctaggat tagaaaagtc
      181 aacctgaatc ttcctgttcc ttatgaacca cctagaagaa aagcgtcgtt aatgatgcat
      241 taaagaacag tcgagatgaa aaaatcgtgt gacgcaccaa gggaggagtc tgcccttttg
      301 aggaaatcta gcgaggaaaa acgatactgg aacagcagaa agtaaaactg acctcatgag
      361 gaggaagaaa gtggctcatg aggtcagggg ttttgtaagt tacatctagt tga
//
LOCUS       DBEJZV010000092          360 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC6 isolate 639553
            SAMN38240105-rid24841123.denovo.92, whole genome shotgun sequence.
ACCESSION   DBEJZV010000092 DBEJZV010000000
VERSION     DBEJZV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240105
            Sequence Read Archive: SRR26818450
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575647.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575647.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 07:58:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,156
            CDSs (total)                      :: 2,117
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 154
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 154
            Pseudo Genes (frameshifted)       :: 69 of 154
            Pseudo Genes (incomplete)         :: 69 of 154
            Pseudo Genes (internal stop)      :: 58 of 154
            Pseudo Genes (multiple problems)  :: 40 of 154
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240105-rid24841123.denovo.92"
                     /strain="GPSC6"
                     /isolate="639553"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
BASE COUNT          104 a           45 c           77 g          134 t
ORIGIN      
        1 gaacagaatc ctctcttgat tgaagacaag ctagtcatta ggctggtttg tctttttgtc
       61 aactgtagtg ggttgatata atagtattag tgagtgggat aaaagtttca tttagtttat
      121 tcagtacaaa tttaacgggt caagatttat atactagtgg tgtttttggg gctgagagaa
      181 gtatcttgat tttatgtgtg gtttttatac ttacagttgt tctgctccaa agagcttgta
      241 gagaagaatt agctcataaa ggagattgat tattttgata tcaaaaaaat gcacaggata
      301 acctgatgca tttttttagc gacaatgctt gctacttcct tctgtcgaat ttagacaatt
//
